WO2015149392A1

WO2015149392A1 - Preparation of traditional chinese medicine for treating chronic colitis and preparation method therefor

Info

Publication number: WO2015149392A1
Application number: PCT/CN2014/075339
Authority: WO
Inventors: 袁志贤
Original assignee: 袁志贤
Priority date: 2014-03-31
Filing date: 2014-04-15
Publication date: 2015-10-08
Also published as: CN103860844A; CN103860844B

Abstract

Preparation of traditional Chinese medicine for treating chronic colitis and preparation method therefor, comprising Magnolia officinalis, Wolfiporia extensa, Tetradium ruticarpum, Astragalus propinquus, licorice, Panax notoginseng, Rheum rhabarbarum, Paeonia lactiflora, Citrus medica sarcodactylis, Dioscorea opposita, Melia toosendan, Dalbergia odorifera, Rhizoma Anemones Altaicae, Asparagus cochinchinensis, cuttlebone, Pinellia ternata, Corydalis yanhusuo, Radix Rehmanniae, and jujube, said ingredients being subjected to processes of powdering, decoction, ethanol extraction and mixing into a composition for liquid preparations.

Description

Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof

The invention relates to a traditional Chinese medicine preparation for treating colitis, in particular to a traditional Chinese medicine preparation for treating chronic colitis and a preparation method thereof. Background technique

The intestine refers to the digestive tract from the pylorus of the stomach to the anus. The intestine is the longest part of the digestive tract and the most important part of the function. The intestine is the largest digestive organ of the human body and the largest detoxification organ in the human body. From the perspective of physiology, anatomy, and cytology, large intestine detoxification accounts for more than 85 % of human detoxification; 80% of the human body's immune structure is around the intestine, and endotoxin accumulation is the killer of autoimmune immunity.

Chronic colitis is a common disease. Clinical manifestations include increased frequency of stools, no grain, or watery or sticky, accompanied by bowel, abdominal pain, and even spleen and kidney. The general disease is in the intestine, but it involves the spleen, stomach, liver, kidney and other organs. It will be thin and burnout for a long time. This card is one of the common spleen and stomach diseases in the clinic. It has a high incidence rate, easy recurrence, and lingering, which seriously affects people's normal life, and the cancer rate is about 5%. Although the drugs currently used to treat colitis are not small, the Western medicine is not a cure for the symptoms, it is easy to produce drug resistance for a long time, the side effects are relatively large, the liver, kidney and blood cells are damaged, and the drug effect is unstable, and it is easy to recur. Summary of the invention The object of the present invention is to provide a traditional Chinese medicine preparation for treating chronic colitis based on the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and in particular to provide such a traditional Chinese medicine preparation and a preparation method thereof, the present invention The treatment of colitis is obvious, and it is non-toxic, has no side effects, and has stable effects. The preparation process is simple and easy.

The technical solution of the present invention is as follows:

The preparation of the invention is from Magnolia officinalis, Poria, Evodia, Radix Astragali, Radix Glycyrrhizae, Radix Notoginseng, Rhubarb, Radix Paeoniae Alba, Bergamot, Yam, Chuanxiongzi, Jiangxiang, Jatropha, Asparagus, Skull, Pinellia, Yanhusuo, Shengdi And a preparation of a composition prepared from red dates, wherein the mass ratio of each component is: Magnolia 12-20g 苓10-22g Wu Wei

8-18g

Astragalus 10-18g Licorice 8-15g Sanqi 10-20g Rhubarb 8-16g White Pelican 12-20g Bergamot 8-16g Yam 10-18g Chuanxiong l()-18g Fragrance

10- 18g

Iris calyx 8-15g asparagus 6-15g thief bone 8-15g pinellia 10-18g yanhusuo 8-16g raw land 8-15g red dates 10-20g.

In order to obtain better results: The preferred raw materials of the present invention: The ratio is: Magnolia 12-18g 茯苓10-18g Wujing 8-12g Astragalus 12-18g Licorice 8-12g Sanqi 10-15g Rhubarb 8-12g White peony 12-16g bergamot 8-12g yam 10-15g medlar 10-14g 10-15g

Iris sinensis 8-12g Asparagus 6- thief bone 8-12g Pinellia 10-15g Yanhusuo habitat 8-12g red dates 12-18g.

Of course, in order to obtain a good effect, the present invention is also preferable to the raw material of Magnolia 15g 茯苓12g Wujing 9g Astragalus 15g Licorice 10g Sanqi 12g Rhubarb 12g White peony 10g Bergamot 8g Yam 12g Chuanxiong 14g Fragrance 12g Iris 8g asparagus 8g thief bone 12g pinellia 10g yanhusuo 8g habitat 10g jujube 15g _c

The above preparation method for treating a chronic colitis traditional Chinese medicine preparation comprises the following steps:

1), put the cockroach into a small pot and stir fry until the surface is slightly coke, then crush it through the pulverizer and pass through the 80 mesh sieve, and set aside;

2), the Magnolia, Wujing, Astragalus, Licorice, Rhubarb, Angelica, Bergamot, Jujube, Pinellia, and Corydalis are proportioned well, crushed into powder by a pulverizer and passed through a 90 mesh sieve, and dried naturally for use;

3), mix the powders of each component in step 1) and 2), add boiling water twice, add 10 times pure water for 1 hour, extract the filtrate for use; 6 times pure water decoction for half an hour, then combine the decoction and filter, spare; 4), the remaining Sanqi, Yam, Chuanxiongzi, Jiangxiang, Iris, asparagus, ribs, and raw land are proportioned well, crushed into powder by a pulverizer and passed through a 80 mesh sieve, and dried naturally. spare;

5), mixing the powders of each component in step 4), adding 4 to 6 times 70%~80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;

6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to 3) the combined decoction in the step, and the mixture is shaken to obtain.

The prepared Chinese medicine composition solution preparation can be used for oral administration, and if it can be consumed once in the morning and evening, and it is used for a long time, the effect is better. The theoretical basis of the present invention is: Magnolia, a medicinal plant belonging to the family Magnoliaceae, and the growth region is mainly in Sichuan, Hubei and the like. Indications of food stagnation, abdominal distension constipation, wet resistance in the coke, vomiting and diarrhea, suffocating, chest full of asthma and cough and other symptoms. It has the effects of stagnation of phlegm and blood stasis, qi and asthma, phlegm and phlegm, and dispelling wind and analgesia. The reflection of saliva, gastric juice, gastrointestinal motility is accelerated, and there is a stomach to help digestion; Decoction has a broad-spectrum antibacterial effect, inhibiting Staphylococcus aureus, hemolytic streptococcus, diphtheria bacilli in vitro; in addition, Magnolia also regulates smooth muscle, anti-ulcer, central inhibition, blood pressure lowering, anti-pathogenic microorganisms , anti-tumor and other effects. 茯苓, sweet, light, flat, medicine has the benefit of water and moisture, spleen and stomach, Ningxin and soothe the nerves, attending urinary unfavorable, edema full, sputum cough, vomiting, modern medical research: 茯苓 can enhance the body The immune function, 茯苓 polysaccharide has obvious anti-tumor and liver-preserving effects. Wu Hao, hot taste, bitter taste, Xin, "The Scriptures" records Wu Hao: "Main temperature in the air, pain, cough, cold, heat, dehumidification, blood stasis, wind and evil, Kai Lili.""Compendium of Materia Medica" records Wu Hao: "Open stagnation, cure phlegm, phlegm and phlegm, headache, yin and stomach pain, phlegm and blood stasis, mouth sore mouth. "There are cold and pain relief, lowering vomiting, used to treat liver and stomach deficiency, yin Headache or stomach cramps caused by turbidity. Astragalus membranaceus, has the benefits of qi and sun, solid table antiperspirant, diuretic swelling, detoxification and myogenic effects. Indications for all qi deficiency and blood loss, such as spleen deficiency diarrhea, lung deficiency cough, rectal prolapse, uterine ptosis, spontaneous sweating, night sweats, edema, blood stasis, sputum is difficult to collapse or long-term collapse. Licorice, a kind of tonic Chinese herbal medicine, the medicinal parts are roots and rhizomes. The roots of the medicinal properties are cylindrical, with spleen and qi, clearing away heat and detoxification, relieving cough, relieving pain, reconciling the effects of various medicines; Weary fatigue, palpitations, shortness of breath, coughing, abdominal pain, sudden pain in the limbs, swollen sores, relieve drug toxicity, potency and so on. Sanqi, used to stop bleeding and dilated blood, reduce swelling and pain. Indications of vomiting blood, hemoptysis, hematuria, blood in the stool, blood stasis, uterine bleeding, postpartum hemorrhage, traumatic bleeding, falling and damaging, chest pain, heartache, chronic pain, syndrome, blood stasis, dysmenorrhea, postpartum stagnation Abdominal pain, sore throat and swelling; combined with other Chinese medicines of the invention, the effect of treating colitis is obvious. Rhubarb, bitter taste, cold, return to the stomach, spleen, large intestine, liver, pericardium, can diarrhea heat the intestines, pass through the phlegm, cool blood detoxification. For blood stasis, bruises, damp heat jaundice, blood heat spitting, real heat constipation, stagnation of abdominal pain, intestinal cramps, abdominal pain, diarrhea, redness, pharyngeal swelling, hemorrhoids, external hemorrhoids Upper gastrointestinal bleeding. For patients with blood stasis and bleeding, attending acute stomach, duodenal ulcer combined with bleeding. White peony, bitter taste, sour, slightly cold, return to the liver. Nourishing blood and camp, relieve pain and relieve pain, and calm the liver. Indications of blood deficiency and cold, abdominal pain, hypochondriac pain, limb pain, menstruation, irregular menstruation, uterine bleeding, spontaneous sweating, night sweats, diarrhea, headache, dizziness. Bergamot, bitter, spicy, sweet, warm, non-toxic, into the liver, spleen, stomach three, with liver and qi, and gastrointestinal pain relief, for liver and stomach qi stagnation, stomach full, less food Vomiting, has obvious inhibitory effect on intestinal smooth muscle, has antispasmodic effect on intestinal fistula; expands coronary vessels and increases coronary flow; high concentration can weaken myocardial contractility, slow heart rate, lower blood pressure, protect heart muscle Ischemia; has a certain sputum effect. Yam, sweet, cool, into the lungs, spleen, kidney, contains amylase, polyphenol oxidase and other substances, is conducive to the digestion and absorption of the spleen and stomach, is a flat-bodied spleen and stomach for food and food. Whether it is spleen yang deficiency or stomach yin deficiency, it can be eaten. Clinically, it is often used together with gastrointestinal drink to treat spleen and stomach weakness, eating less body fatigue, diarrhea and other diseases. Invigorating the spleen, nourishing the lungs, solidifying the kidney, benefiting the essence; attending spleen deficiency and diarrhea, eating less edema, lung deficiency and cough, thirst, nocturnal emission, taking down, kidney deficiency and frequent urination. Chuanxiongzi, bitter taste, cold; small poison, liver, small intestine, bladder. Shugan qi and pain, deworming. For chest flank, abdominal pain, pain, abdominal pain. Decline, sexual, warm, return to the liver, spleen. Exercise qi and blood, relieve pain, stop bleeding. For abdominal pain, liver depression, hypochondriac pain, chest pain, puncture injury, traumatic bleeding; and vomiting and abdominal pain caused by cold pain or turbid internal resistance. Iris, sweet, mild, non-toxic; heart, liver, spleen, with phlegm and phlegm, soothe the nerves, Xuan spleen, detoxification; main fever, dizziness, epilepsy, air-closed deafness, dreams, forgetful, Chest tightness, bloating, loss of appetite, rheumatism, phlegm, phlegm and other symptoms. Asparagus, taste: sweet, bitter, cold; return to the lungs, kidney. For yin deficiency fever, dry lung cough, fatigue cough, Tianjin wound thirst, upset insomnia, internal heat and thirst, intestinal dry constipation, lung sputum, lung sputum, diphtheria and other symptoms; inhibition of a variety of bacteria, anti- Tumor activity, can nourish yin and spleen, moisten the lungs and clear the heart, remove dryness and reduce fire. Cuttlefish bone, containing calcium carbonate, can neutralize stomach acid, relieve symptoms of vomiting and heartburn, promote inflammation of the ulcer surface, prevent bleeding, relieve local pain. It can be used as an antacid. Experiment shows: its compound preparation Wubei San It has obvious adsorption of pepsin and neutralizes gastric acid, which can reduce the stimulation of gastric ulcer on gastric ulcer surface and reduce the digestion of protease on the ulcer surface, which is beneficial to the stomach. Pinellia, spicy, warm, poisonous. Return to the spleen, stomach, lungs. It has the functions of dampness and phlegm, lowering vomiting, eliminating phlegm and dissipating sputum; attending cough and phlegm, vomiting and nausea, chest fullness, headache, dizziness, night restlessness, sputum nucleus, carbuncle swollen poison embolism. Corydalis, temperature, taste, bitterness, liver, spleen, stomach, is a wonderful product of promoting blood circulation, relieving pain and relieving pain, especially known for its anti-pain effect. Indications for chest flank, abdominal pain, menstrual dysmenorrhea, postpartum stagnation, swelling and swelling. Birthplace, sweet, bitter, cold; heart, liver, lung. Cool serum heat, nourishing yin and tonifying kidney, Shengjin quenching thirst, often used to treat bone steaming heat, sore throat, bloody sputum. In combination with other traditional Chinese medicines of the invention, the curative effect is remarkable. Jujube, jujube is warm and sweet, contains protein, fat, sugar, calcium, phosphorus, iron, magnesium and rich vitamins. It also contains carotene, etc. It is very rich in nutrients. It has the functions of tonifying the spleen, nourishing the blood, calming the nerves, and regulating the blood. It has the functions of moistening the lungs and relieving pain, and relaxing the bowels and laxatives. It has the functions of moistening the lungs and strengthening the spleen, relieving cough, supplementing the five internal organs, and treating the deficiency. From the perspective of traditional Chinese medicine, the traditional Chinese medicine for chronic colitis is classified as "diarrhea" and "white peony". The clinical symptoms are chronic diarrhea, abdominal pain, mucus and bloody stools, chronic recurrent or persistent seizures. The course of the disease is longer, mostly due to long-term unhealthy diet, fatigue and internal injuries, resulting in weakness of the spleen and stomach. The combination of the above traditional Chinese medicine and the preparation method can effectively achieve the effect of regulating the intestinal tract and the internal organs by using a dialectical method, has no toxic and side effects, and has stable effects, and achieves twice the result with half the effort with western medicine. Clinical Experiment 1:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the six months from April 2011 to September 2011 are selected. 2), observation object: 10 cases of chronic colitis were selected in the Department of Gastroenterology, Shenzhen Hospital of Guangdong Province: 5 males and 5 females; age: 5 cases of 41-55 years old, 5 cases of 62-75 years old; occupation: ordinary There are 5 office workers and 5 retirees. Symptoms: recurrent abdominal pain, bloating, diarrhea, diarrhea mucus or pus and bloody stools, 3 times per day of bowel movements, with poor bowel movements or urgency; the tongue is yellowy or greasy; all diseases are treated with fiberoptic colonoscopy Check the diagnosis.

3), How to use: The oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses of treatment as therapeutic effects.

4), observation effect:

After taking 3 courses of treatment continuously, the clinical symptoms and signs disappeared, the fiber colonoscopy was normal, and 4 cases of intestinal mucosal lesions returned to normal. The clinical symptoms were alleviated, the signs disappeared, the fiber colonoscopy was improved, and the intestinal mucosal lesions were obvious. In the 4 cases improved, there were no improvement in clinical symptoms and signs before and after treatment, and 2 cases with no improvement in fiber colonoscopy, the total effective rate was 80%.

Clinical trial 2:

1) Observation time: In the case that the technical solution of the present invention has not been disclosed, the time from February 2011 to July 2011 is selected.

2), Observed subjects: 20 cases were selected in the Department of Gastroenterology, Futian District Hospital, Shenzhen, Guangdong Province: 10 males and 10 females; Age: 10 cases of 33-55 years old, 10 cases of 58-75 years old; Occupation: There were 10 civil servants in leadership positions and 10 in general. Symptoms: recurrent abdominal pain, bloating, diarrhea, diarrhea mucus or pus and bloody stools, 3 times per day of bowel movements, with poor bowel movements or heavy urgency; thick yellow tongue or greasy tongue; all diseases are treated with fiber enteroscopy Check the diagnosis. 3), How to use: The oral liquid of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for 1 course of treatment, and 3 courses of treatment as therapeutic effects.

4), observation effect:

After taking 3 courses of treatment, the clinical symptoms and signs disappeared, the fiber colonoscopy was normal, and 10 cases of intestinal mucosal lesions returned to normal. The clinical symptoms were obviously relieved, the signs disappeared, the fiber colonoscopy was improved, and the intestinal mucosal lesions were obvious. In 5 cases improved, there were no improvement in clinical symptoms and signs before and after treatment. There were 5 cases of no improvement in fiber colonoscopy, and the total effective rate was 75%.

Clinical Trial 3:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the six months from June 2013 to November 2013 are selected.

2), Observed subjects: 30 cases were selected in the Department of Gastroenterology, Songgang People's Hospital, Shenzhen, Guangdong Province: 14 males and 16 females; Age: 16 cases of 35-55 years old, 14 cases of 60-75 years old; Occupation: Ordinary private enterprise There are 14 main cases and 16 ordinary retired teachers. Symptoms: recurrent abdominal pain, bloating, diarrhea, diarrhea mucus or pus and bloody stools, 3 times/day of bowel movements during episodes, with poor bowel movements or heavy urgency; thick yellow tongue or greasy tongue; all diseases are treated with fiber enteroscopy Check the diagnosis.

3), How to use: The oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.

4), observation effect:

After taking 3 courses of treatment continuously, the clinical symptoms and signs disappeared, the fiber colonoscopy was normal, and 20 cases of intestinal mucosal lesions returned to normal. The clinical symptoms were alleviated, the signs disappeared, the fiber colonoscopy was improved, and the intestinal mucosal lesions were obvious. 5 cases improved, clinical before and after treatment No improvement in symptoms and signs, 5 cases of no improvement in fiber colonoscopy, total effective rate 84% _t combined with the above clinical data and the theoretical basis of the present invention, it can be seen that the beneficial effects of the present invention are that the preparation prepared by the present invention is for treatment Chronic colitis has good effects, and it is non-toxic, has no side effects, and has a stable effect. The preparation process is simple and easy. Concrete real

The present invention will be described in detail below with reference to the embodiments:

Example 1:

The preparation of the invention is from Magnolia officinalis, Poria, Evodia, Radix Astragali, Radix Glycyrrhizae, Radix Notoginseng, Rhubarb, Radix Paeoniae Alba, Bergamot, Yam, Chuanxiongzi, Jiangxiang, Jatropha, Asparagus, Skull, Pinellia, Yanhusuo, Shengdi And the preparation of the composition prepared by the red jujube, wherein the mass ratio of each component is: Magnolia 12g 茯苓10g Wujing 10g Astragalus 12g Licorice 12g Sanqi 15g Rhubarb 10g White Pelican 12g Bergamot 8g Yam 15g Chuanxiong 15g Fragrance 13g Festival Iris 12g asparagus 8g thief bone 10g Pinellia 12g Yanhusuo 13g soil 10g jujube 16g.

The preparation method of the traditional Chinese medicine preparation for treating chronic colitis includes the following steps: 1) placing the cockroach into a small pot for small frying until the surface is slightly coke, and then pulverizing through a pulverizer and passing through a 80 mesh sieve for use; 2), the magnolia, Wujing, Astragalus, licorice, rhubarb, white peony, bergamot, red dates, pinellia, yanhusuo are proportioned well, pulverized into powder after crushing machine and passed through a 90 mesh sieve, naturally dried, ready for use;

3), mix the powders of each component in steps 1) and 2), add boiling water twice, add 8 times pure water for 1 hour, simmer for 1 hour, and add 4 times for the second time. Decoction in pure water for half an hour, then combine the decoction and filter, set aside;

4), the remaining Sanqi, Yam, Chuanxiongzi, Jiangxiang, Iris, asparagus, ribs, and raw land are proportioned well, crushed into powder by a pulverizer and passed through a 80 mesh sieve, and dried naturally. Standby

6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to the combined decoction in the step 3), and mixed and shaken to obtain.

The preparation of the above-mentioned traditional Chinese medicine composition solution can be used for oral administration, and if it can be consumed once in the morning and evening and long-term drinking, the effect is better.

Example 2:

The preferred raw material quality of the present invention is (g):

Magnolia 12g 茯苓10g Wu Hao 10g Huang Qi 12g Licorice 12g Sanqi 15g Rhubarb 10g White peony 12g Bergamot 8g Yam 15g Chuanxiong 10g Fragrance 13g Iris pupa 12g Asparagus 8g Rib bone 10g Pinellia 12g Corydalis 13g Raw land 10g Red date 16g ₀

The preparation method is as in Example 1.

Example 3:

The preferred raw material quality of the present invention is (g):

Magnolia 15g 茯苓12g Wujing 9g Astragalus 15g Licorice 10g Sanqi 12g Rhubarb 12g White peony 10g Bergamot 8g Yam 12g Chuanxiong 14g Fragrance 12g Jatropha 8g Asparagus 8g Rib bone 12g Pinellia 10g Corydalis 8g Fertile land 10g Jujube 15g _c

The preparation method is as in Example 1.

Example 4:

The preferred raw material quality of the present invention is (g):

Magnolia 18g 茯苓15g Wu Wei 12g Huang Qi 16g Licorice 12g Sanqi 15g Rhubarb 13g White Pelican 15g Bergamot 12g Yam 16g Chuanxiong 14g Fragrance 16g Jatropha 10g Asparagus 12 Rib bone 15g Pinellia 16g Yanhusuoshengdi 12g Jujube 18g.

The preparation method is as in Example 1.

Example 5

The preferred raw material quality of the present invention is (g):

Magnolia 16g 茯苓 18g Wujing 15g Huangqi 14g Licorice 15g Sanqi 18g Rhubarb 15g White peony 18g Bergamot 14g Yam 18g Chuanxiong 16g Fragrance 14g Iris chinensis 12g Asparagus 13 Rib bone 13g Pinellia 18g Yanhusuo 15g Jujube 18g.

The preparation method is as in Example 1.

Example 6:

The preferred raw material quality of the present invention is (g):

Magnolia 15g 茯苓18g Wujing 15g Astragalus 16g Licorice 15g Sanqi 20g Rhubarb 12g White peony 20g Bergamot 16g Yam 16g Chuanxiong 18g Fragrance 15g Jatropha 15g Asparagus 15g Rib bone 12g Pinellia 16g Yanhusuo 16g Biographa 13g Red dates 20g.

The preparation method is as in Example 1.

The above embodiments are only a few of the various embodiments of the present invention. For example, if the formula is increased or decreased according to the ratio in the technical solution, the therapeutic effect of the preparation of the chronic colitis preparation is not affected, and It is within the scope of the protection of the present invention.

Claims

Rights request

1. A traditional Chinese medicine preparation for the treatment of chronic colitis, characterized in that the preparation of the present invention is composed of Magnolia officinalis, Poria cocos, Evodia, Astragalus, licorice, Panax notoginseng, rhubarb, white peony root, bergamot, yam, toodandan, agarwood, A composition preparation prepared from Acorus calamus, Asparagus Asparagus, Cortex Pinellia, Corydalis Corydalis, Rehmannia Rehmanniae and Jujube, in which the mass ratio of each component is:

Magnolia officinalis 12-20g

10-22g

8-18g

Astragalus 10_18g Licorice 8-15g

10-20g

Rhubarb 8-16g, white peony root 12-20g, bergamot 8-16g, yam 10-18g, toodan 10-18g

10-18g

Acorus calamus 8-15g Asparagus 6-15g Thieves bone 8-15g Pinellia ternata 10-18g Corydalis 8-16g Rehmannia 8-15g Red dates 10-20g.

2. The traditional Chinese medicine preparation for treating chronic colitis according to claim 1, further characterized in that the mass ratio of each component is:

Magnolia officinalis 12_18g Ling 10-18g Evodia

8-12g

Astragalus 12-18g, licorice 8-12g, Panax notoginseng 10-15g, rhubarb 8-12g, white peony root 12-16g, bergamot 8-12g, yam 10-15g, neem 10-14g 10-15g

Cortex calamus 8-12g Asparagus Asparagus 6-10g Thieves bone 8-12g Pinellia ternata 10-15g Corydalis 8-12g Rehmannia 8-12g Red dates 12-18g.

3. The traditional Chinese medicine preparation for treating chronic colitis according to claim 1 or 2, further characterized in that the mass ratio of each component is

Magnolia officinalis 15g Poria 12g Evodia 9g Astragalus 15g Licorice 10g Panax notoginseng 12g Rhubarb 12g White peony root 10g Bergamot 8g

12g Chinese yam, 14g Melanium japonica, 12g Acorus calamus 8g Asparagus asparagus 8g, 12g Pinellia ternata 10g, Corydalis 8g, Rehmannia glutinosa 10g, red dates 15g _c

4. A method for preparing a traditional Chinese medicine preparation for treating chronic colitis, which is characterized in that it includes the following steps:

1). Put Poria cocos into a small pot and fry until the surface is slightly charred, then grind it with a grinder and pass it through an 80-mesh sieve, and set aside;

2). Mix magnolia bark, Evodia, astragalus, licorice, rhubarb, white peony root, bergamot, red dates, pinellia, and Corydalis in proportion, crush it into powder through a grinder and pass through a 90-mesh sieve, dry naturally and set aside;

3). Mix the powders of each component in steps 1) and 2) together, add purified water and cook twice. For the first time, add 10 times purified water and cook over low heat for 1 hour. Extract the filtrate and set aside. For the second time, add 6 times purified water and simmer over low heat for half an hour, then combine the decoctions and filter, set aside;

4). Mix the remaining Panax notoginseng, Chinese yam, toodandan, alfalfa, calamus, asparagus, bone, and raw rehmannia in proportion, grind into powder through a grinder and pass through an 80-mesh sieve, and dry naturally. spare; spare

5). Mix the powders of each component in step 4) together, add 4 to 6 times of 70% to 80% ethanol, heat and reflux for 3 to 5 hours, extract and filter to obtain the filtrate; then add the remaining medicinal residue. Add 2 to 4 times of 65% to 75% ethanol again, heat and reflux for 2 to 3 hours, extract and filter to obtain the filtrate; combine the two filtrate obtained together, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste. ;

6). Ultrafinely pulverize the dry paste obtained in the above step 5) into powder and pass it through a 200 mesh sieve. Then add the powder to the combined decoction in step 3), mix and shake well to prepare. The prepared above-mentioned Chinese medicine composition solution preparation can be taken orally. If it can be drunk once in the morning, noon and evening in an appropriate amount and for a long time, the effect will be better.