CN101785847A - Traditional Chinese medicine combination for intestinal caner treatment and preparation method thereof - Google Patents
Traditional Chinese medicine combination for intestinal caner treatment and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a new traditional Chinese medicine combination for intestinal cancer treatment and a preparation method thereof; the traditional Chinese medicine combination consists of the following raw medicines: semen coicis, natural indigo, andrographis paniculata, sunburn corydalis yanhusuo, sunburn frankincense, sunburn myrrh, sunburn common burreed rhizome, curcuma, cyperus rotundus, peach kernel, safflower, sunburn pangolins, poria, citrus aurantium, dalbergia, szechuan lovage rhizome, eupolyphaga, root of Chinese trichosanthes, dragon's blood, radix sophorae flavescentis, angelica, rubiaceae, amomum and the like. The traditional Chinese medicine combination can be prepared into any type of common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can significantly improve the symptoms of hematochezia, anemia, borborygmus, abdominal pain, abdominal distension, constipation, diarrhea, intestinal obstruction, diffuse peritonitis, internal hemorrhoids, transverse colon cancer penetration stomach, weight loss, neoplastics fever and other symptoms; the traditional Chinese medicine combination has remarkable clinical curative effect, significant and quick effect. As the traditional Chinese medicine combination basically combines medicinal and edible medicine sources specified in the National Formulary, the traditional Chinese medicine combination has low cost and basically has no toxic and side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of intestinal cancer.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment intestinal cancer of crude drug with the Chinese herbal medicine.
Background technology
Intestinal cancer is common malignancy in the gastrointestinal tract, and sickness rate is only second to the gastric cancer and the esophageal carcinoma, is the most common part (accounting for about 60%) of colorectal cancer.Most humans is more than 40 years old, and person below 30 years old accounts for 15%.Clinically have blood in stool, symptom such as anemia, borborygmus, stomachache, abdominal distention, constipation, diarrhoea, intestinal obstruction, diffuse peritonitis, internal hemorrhoid, horizontal colon cancer penetrating into the stomach, weight loss, neoplastic fevers, descend opposite year by year with most of cancer morbidity, the sickness rate of intestinal cancer just rises with average annual 2% speed in the world, and the speedup of China's intestinal cancer sickness rate is the twice of world average level, reaches average annual 4%.
The cause of disease of intestinal cancer is unclear so far, modern medicine affects the state of an illness adversely, in order to overcome above-mentioned defective lacking effective measures and way aspect prevention and the treatment intestinal cancer, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment intestinal cancer, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out the natural plant of the body resistance strengthening and constitution consolidating, softening the hard mass knot, diffusing swollen toxin expelling, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment intestinal cancer that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
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Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment disease of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of intestinal cancer of the present invention, the component of main following weight portion is formed:
1～300 part of Semen Coicis, 1～120 part of Indigo Naturalis, 1～120 part of Rhizoma Polygoni Cuspidati, 1～100 part of Herba Andrographis, process 1～100 part of rhizoma corydalis, 1～60 part of Olibanum (processed), 1～60 part of Myrrha (processed), 1～60 part of rhizoma sparganic, 1～60 part of Rhizoma Curcumae, 1～150 part of Pericarpium Citri Reticulatae, 1～120 part of Radix Aucklandiae (Radix Vladimiriae), 1～150 part of Rhizoma Cyperi, 1～100 part of Radix Curcumae, 1～50 part in Semen Persicae, 1～50 part on Flos Carthami, 1～50 part of Squama Manis (processed), 1～50 part of Hirudo, 1～100 part of Radix Et Rhizoma Rhei, 1～150 part of Massa Medicata Fermentata, 1～300 part in Poria, 1～150 part of Radix Trichosanthis, 1～200 part of the Radix Paeoniae Alba, 1～100 part of Radix Paeoniae Rubra, 1～50 part of Radix Ginseng, 1～30 part of Sanguis Draxonis, 1～120 part of Radix Sophorae Flavescentis, 1～60 part of Semen Pruni, 1～120 part of Cortex Magnoliae Officinalis, 1～150 part of Fructus Aurantii Immaturus, 1～120 part of Fructus Toosendan, 1～120 part of the Radix Linderae, 1～120 part in Fructus Hordei Germinatus, 1～120 part of Semen Raphani, 1～100 part of Radix Notoginseng, 1～120 part in Radix Rubiae, 1～120 part of Lignum Dalbergiae Odoriferae, 1～100 part of Styrax, 1～120 part of Rhizoma Chuanxiong, 1～100 part of Radix Salviae Miltiorrhizae, 1～60 part of Eupolyphaga Seu Steleophaga.
Be preferably:
150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, 30 parts of Rhizoma Polygoni Cuspidati, 30 parts of Herba Andrographis, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 15 parts of Hirudos, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 15 parts of Radix Ginsengs, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of the Radixs Linderae, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 30 parts of Styrax, 30 parts of Rhizoma Chuanxiongs, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Eupolyphaga Seu Steleophagas.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1～100 part of Fructus Gardeniae, 1～120 part of Radix Scutellariae, 1～100 part of Rhizoma Atractylodis, 1～120 part of Radix Sophorae Tonkinensis, 1～60 part of Radix Stephaniae Tetrandrae, 1～120 part of Flos Lonicerae, 1～120 part of Herba Taraxaci, 1～100 part of Radix Rehmanniae, 1～100 part of Radix Arnebiae (Radix Lithospermi), 1～50 part of Pseudobulbus Bletillae (Rhizoma Bletillae), 1～150 part of Radix Puerariae, 1～50 part of Flos Caryophylli, 1～50 part of Fructus Amomi, 1～50 part of Semen Alpiniae Katsumadai, 1～100 part of Endothelium Corneum Gigeriae Galli, 1～150 part of Radix Astragali, 1～120 part of the Rhizoma Atractylodis Macrocephalae, 1～150 part of Rhizoma Dioscoreae, 1～120 part of Radix Codonopsis, 1～60 part of Fructus Cannabis.
Be preferably:
20 parts of Fructus Gardeniaes, 30 parts of Radix Scutellariaes, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 15 parts of Radixs Stephaniae Tetrandrae, 20 parts of Flos Loniceraes, 20 parts of Herba Taraxaci, 30 parts of Radix Rehmanniae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 100 parts of Radix Puerariaes, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 20 parts of Semen Alpiniae Katsumadai, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis, 15 parts of Fructus Cannabiss.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 3～5 grams, warm water takes.4) granule: every day three times.Each 3～5 grams, warm water takes.5) powder: every day three times, each 2～4 grams, warm water takes.
The treatment that the present invention is directed to the intestinal cancer patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: 150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: 150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: 150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating intestinal cancer of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 139 routine patients altogether, wherein male 71 examples, women 68 examples; The oldest person 78 years old, the age reckling has only 26 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 3～5 grams, warm water takes.4) granule: every day three times.Each 3～5 grams, warm water takes.5) powder: every day three times, each 2～4 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 18 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: the tumor body disappears, and diet, rest and stool are normal.The patient does not have any bad sensation, and is happy, in high spirits.
Produce effects: the tumor body significantly dwindles, and diet, rest and stool are normal substantially.The patient feels better, and is happy, in high spirits.
Effectively: the disappearance that diminishes of tumor body, diet, rest and stool are improved.Patient's mood is comparatively happy, and spirit better.
Invalid: sign does not have any change, symptom such as preceding.
Four, model case:
1, Wu so-and-so, woman, 37 years old, office worker.
Medical history: the patient suffered from carcinomaofsigmoid at the beginning of 4 months nineteen nineties, ectomed and carried out chemotherapy through certain tumour hospital.Behind the first quarter moon, obviously weak because of muscle power, to feel sick, vomiting is to stop chemotherapy, the request Chinese traditional treatment.When examining, patient's poor appetite abdominal distention, stomachache, diarrhoea, dizzy and heavy, cardiopalmus, limb paralysis, blood pressure 170/100mmHg; Fasting glucose 6.8mmol/L, 2 hours after the meal blood glucose 9.9mmol/L, tongue is dim red, yellow and greasy fur, stringy and rolling pulse.
Took Chinese medicine composition of the present invention 7, stomachache alleviates, diarrhoea number of times minimizing Summer Solstice or the Winter Solstice 7-10 time, continue and obeyed Chinese medicine composition of the present invention 15, blood pressure is reduced to 130/80mmHg, and oneself ends cardiopalmus, it is normal substantially to defecate, and day 1-2 time, is shaped, the stomachache sill disappears, dizzy, empty weary the improvement felt sick and removed, and spirit is gradually bright, diet is cumulative, the slightly good commentaries on classics of complexion.Continue and obeyed Chinese medicine composition of the present invention 3 months, transference cure, two is just normal, and antisecosis is very fast, and hemogram and B ultrasonic, CT etc. check all normal.Continue and obeyed Chinese medicine composition of the present invention 1 year, fasting glucose is reduced to 6.2mmol/L, blood pressure 120/80mmHg, and non-evident sympton, movable as usual, follow up a case by regular visits to so far, as usual substantially, adhere to working work.
2, Wang, man, 59 years old, cadre.
Medical history: the patient was admitted to hospital because of the difficult defecation of having blood in stool in 1 year, was diagnosed as: carcinomaofsigmoid.The carcinomaofsigmoid radical correction that moves ahead April, the postoperative pathological replacement: differentiation adenocarcinoma companion lymphocytic transformation cancer is invaded and placenta percreta in the sigmoid colon ulcer type.Postoperative is vomitted because of the paroxysmal abdominal pain companion February, and private prosecution still has abdominal distention, and dyschesia comes here to require Chinese traditional treatment.Symptom: fever of the body is thirsty, uncomfortable in chest breathing with cough, dysphoria, gastral cavity abdominal distention painful abdominal mass, lower abdomen pain with tenderness, constipation with dry stool, delegation on the 5th, 6, oliguria with reddish urine, xerostomia halitosis, red tongue with yellowish and greasy fur, slippery and rapid pulse.
Take 1 first quarter moon of Chinese medicine composition of the present invention, the light gas of body is refreshing, and spirit is happy, and stomachache is removed, and free movement of the bowels continues and obeyed Chinese medicine composition of the present invention 3 months, and malaise symptoms disappears substantially, and symptom is greatly taken on a new look.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, during situation stable, not different from discomfort, body colour are all good, and be energetic, just diet two is all normal, conscious body is strong as ordinary person.
3, Zhang, man, 56 years old, driver.
The patient feels uncomfortable October calendar year 2001, and times of defecation increases, and feces attenuates, the sticking blood of band, have defecation to feel not to the utmost, November 4 went to see a doctor, by rectal touch, and endorectal ultrasound scanning, do pathological changes tissue pathology checking, be diagnosed as rectal cancer, 7.6 * 6.5cm.Begin to accept radiotherapy November 15 calendar year 2001, reacts too strong in the radiotherapy process, once once ended.
Took Chinese medicine composition of the present invention 1 month, focus size 6.1 * 4.9cm, times of defecation reduces, remission.Obeyed Chinese medicine composition of the present invention 3 months, focus size 4.6 * 3.2cm, the accidental band of defecating glues blood, and symptom is greatly taken on a new look.Continue and obeyed Chinese medicine composition of the present invention nearly 1 year, the focus complete obiteration, the patient gets well, and does not have uncomfortable symptom, follows up a case by regular visits to and does not see recurrence so far.
4, Zhang, man, 62 years old, retired worker.
Medical history: go to a doctor in certain hospital because of 2 weeks of having blood in stool in November, 1999, and per rectum refers to inspections such as inspection, romanoscope, CT, and colonoscope sees that there is 2cm * 3cm at the rectum place, big or small obscure boundary ulcer, and the surface is visible rotten to the corn hemorrhage; The histocytology inspection is a tubular adenocarcinoma; CT does not see regional glandular enlargement, is diagnosed as rectal cancer, and the row rectal cancer surgery is also made paralysis and left over otch, and postoperative pathology is tubular adenocarcinoma.The capable local radiotherapy of postoperative and 3 courses of treatment of systemic chemotherapy.Disease is seen: dizzy and heavy, idol has the left hand numbness, moving then cardiopalmus, and the poor appetite gastral cavity is bloated.Tongue is dim red, yellow and greasy fur, stringy and rolling pulse.
Took Chinese medicine composition of the present invention 1 month, cardiopalmus is fixed, and surplus disease is gradually slow.Continue and obeyed Chinese medicine composition of the present invention 4 months, band blood during idol has just, diet increases, and malaise symptoms disappears substantially, and symptom is greatly taken on a new look.Continue and obeyed Chinese medicine composition of the present invention 11 months, every inspection is all normal, follows up a case by regular visits to so far, and situation is stable.
5, Yu, woman, 68 years old, peasant.
Lose the sight of both eyes since the childhood, diarrhoea companion had blood in stool 1 year half, was diagnosed as rectal cancer through the doctor trained in Western medicine inspection, and family members do not give operative treatment for some reason, examine upon somebody's introduction.Patient diarrhoea as water with small amounts of blood, surplus day row 20 time, stomachache not very, anus weighs down and rises, the poor appetite bitter taste is weak, oliguria, the red tongue tongue is bored with in vain, thready and rolling pulse.
Took Chinese medicine composition of the present invention 7, just reduce to 10 surplus time, it is rare slightly to defecate.Continue and obeyed Chinese medicine composition of the present invention 3 months, stool is clearly better, and anus still has to weigh down and rises, and it is accidental a small amount of to have blood in stool, receive to increase, and the more preceding increase of muscle power, symptom is greatly taken on a new look.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and patient's situation is stable, and sign is normal, just diet two is all normal in 3 years as ordinary person.
6, Ni, woman, 49 years old, workman.
Found before January that abdominal part has lump, stool attenuates, and is diagnosed as colon cancer on inspection, row colon cancer excision.Because chemotherapy for several times behind the corrective surgery has a delicate constitution, adding has the cholelithiasis medical history originally, so the upper right abdomen pain of normal appearance is received not fragrantly, emotion is fidgety, greasy fur, thready and stringy pulse.
Took Chinese medicine composition of the present invention 7, right hypochondrial region slightly alleviates, and appetite strengthens, and surplus card is the same, continues and obeys Chinese medicine composition of the present invention 15, and upper right abdominal distention and pain disappears, and spirit also takes a turn for the better, and self-induction muscle power strengthens, and is convenient to both as usual.Continue and obeyed Chinese medicine composition of the present invention 15, the patient is energetic, and it is flourish that complexion is changeed, weight increase, Na Guxiang, the peace of getting into bed night.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, all diseases by and all remove, the examination in hospital cancerous protuberance is not seen recurrence, outpatient service is followed up a case by regular visits to so far, the life of daily life at present is as usual, and is happy comfortable.
7, military certain, man, 67 years old, engineer.
Stool hematochezia 7 years increases the weight of January, is diagnosed as rectal cancer in hospital.Hospital advises its operation of being in hospital, and family members and he or she consider: the one, and the age is bigger, moreover fears that waist hangs colostomy bag, and the three considers not necessarily success of operation.More repeatedly, operation is abandoned in decision.Examine quarter: spirit can, often feel weak, the equal hematochezia of at every turn defecating does not have stomachache.Thin fur, the stringy and rolling pulse number.
Took Chinese medicine composition of the present invention 7, times of defecation reduces, and hemafecia disappears.Continue and obeyed Chinese medicine composition of the present invention 3 months, malaise symptoms is significantly alleviated, the more preceding recovery of muscle power, and symptom is greatly taken on a new look.Continue and obeyed Chinese medicine composition of the present invention nearly 1 year, non-evident sympton, situation is stable, and it is as usual to live.
8, Liu, man, 52 years old, cadre.
1999 are undesired because of defecation, are diagnosed as rectal cancer through pathology, do γ cutter treatment in March, 2000 after, adhesion, edema, difficult defecation appear in intestinal.In July, 2000, surgical radical treatment continuously through 5 chemotherapy, dizzy, cardiopalmus occurred, symptoms such as easy catching a cold, and hemogram reduces; Once took treatment by Chinese herbs in the locality.On December 19th, 2000, the CT examination prompting: the rectal cancer recurrence, and go to a doctor August 18 calendar year 2001.
Took Chinese medicine composition of the present invention 1 month, dizzy, cardiopalmus sx, the frequent micturition of Lianping day, dysurea phenomenon also take a favorable turn, and require to continue to take medicine.Obeyed Chinese medicine composition of the present invention 3 months, rectal cancer recurrence place is controlled effectively, does not continue development, has platelet, leukocyte only and still is lower than normal value, and symptom is greatly taken on a new look.The clothes Chinese medicine composition of the present invention 1 year that continues, situation is stable, does not have uncomfortable symptom, and several organs abnormalities such as liver,spleen,kidney that do not occur are on inspection now lived very happyly.
Five, therapeutic outcome:
In the 139 routine cases of being accepted for medical treatment,, wherein cure 27 examples through treatment in 18 months, produce effects 45 examples, effective 49 examples, invalid 18 examples, total effective rate reaches 87%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment intestinal cancer patient.
Claims (7)
1. Chinese medicine composition for the treatment of intestinal cancer is characterized in that: mainly contain following bulk drugs and form:
1～300 part of Semen Coicis, 1～120 part of Indigo Naturalis, 1～120 part of Rhizoma Polygoni Cuspidati, 1～100 part of Herba Andrographis, process 1～100 part of rhizoma corydalis, 1～60 part of Olibanum (processed), 1～60 part of Myrrha (processed), 1～60 part of rhizoma sparganic, 1～60 part of Rhizoma Curcumae, 1～150 part of Pericarpium Citri Reticulatae, 1～120 part of Radix Aucklandiae (Radix Vladimiriae), 1～150 part of Rhizoma Cyperi, 1～100 part of Radix Curcumae, 1～50 part in Semen Persicae, 1～50 part on Flos Carthami, 1～50 part of Squama Manis (processed), 1～50 part of Hirudo, 1～100 part of Radix Et Rhizoma Rhei, 1～150 part of Massa Medicata Fermentata, 1～300 part in Poria, 1～150 part of Radix Trichosanthis, 1～200 part of the Radix Paeoniae Alba, 1～100 part of Radix Paeoniae Rubra, 1～50 part of Radix Ginseng, 1～30 part of Sanguis Draxonis, 1～120 part of Radix Sophorae Flavescentis, 1～60 part of Semen Pruni, 1～120 part of Cortex Magnoliae Officinalis, 1～150 part of Fructus Aurantii Immaturus, 1～120 part of Fructus Toosendan, 1～120 part of the Radix Linderae, 1～120 part in Fructus Hordei Germinatus, 1～120 part of Semen Raphani, 1～100 part of Radix Notoginseng, 1～120 part in Radix Rubiae, 1～120 part of Lignum Dalbergiae Odoriferae, 1～100 part of Styrax, 1～120 part of Rhizoma Chuanxiong, 1～100 part of Radix Salviae Miltiorrhizae, 1～60 part of Eupolyphaga Seu Steleophaga.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:
150 parts of Semen Coiciss, 30 parts of Indigo Naturaliss, 30 parts of Rhizoma Polygoni Cuspidati, 30 parts of Herba Andrographis, process 50 parts of rhizoma corydalis, 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 20 parts of rhizoma sparganic, 20 parts of Rhizoma Curcumae, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 100 parts of Rhizoma Cyperis, 20 parts of Radix Curcumaes, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 20 parts of Squama Manis (processed), 15 parts of Hirudos, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 150 parts in Poria, 30 parts of Radix Trichosanthis, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 15 parts of Radix Ginsengs, 10 parts of Sanguis Draxonis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Semen Prunis, 30 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantii Immaturuss, 30 parts of Fructus Toosendans, 20 parts of the Radixs Linderae, 50 parts in Fructus Hordei Germinatus, 30 parts of Semen Raphanis, 50 parts of Radix Notoginseng, 50 parts in Radix Rubiae, 20 parts of Lignum Dalbergiae Odoriferaes, 30 parts of Styrax, 30 parts of Rhizoma Chuanxiongs, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Eupolyphaga Seu Steleophagas.
3. according to the described Chinese medicine composition of claim 1, wherein crude drug also has:
1～100 part of Fructus Gardeniae, 1～120 part of Radix Scutellariae, 1～100 part of Rhizoma Atractylodis, 1～120 part of Radix Sophorae Tonkinensis, 1～60 part of Radix Stephaniae Tetrandrae, 1～120 part of Flos Lonicerae, 1～120 part of Herba Taraxaci, 1～100 part of Radix Rehmanniae, 1～100 part of Radix Arnebiae (Radix Lithospermi), 1～50 part of Pseudobulbus Bletillae (Rhizoma Bletillae), 1～150 part of Radix Puerariae, 1～50 part of Flos Caryophylli, 1～50 part of Fructus Amomi, 1～50 part of Semen Alpiniae Katsumadai, 1～100 part of Endothelium Corneum Gigeriae Galli, 1～150 part of Radix Astragali, 1～120 part of the Rhizoma Atractylodis Macrocephalae, 1～150 part of Rhizoma Dioscoreae, 1～120 part of Radix Codonopsis, 1～60 part of Fructus Cannabis.
4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:
20 parts of Fructus Gardeniaes, 30 parts of Radix Scutellariaes, 30 parts of Rhizoma Atractylodis, 40 parts of Radix Sophorae Tonkinensiss, 15 parts of Radixs Stephaniae Tetrandrae, 20 parts of Flos Loniceraes, 20 parts of Herba Taraxaci, 30 parts of Radix Rehmanniae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 100 parts of Radix Puerariaes, 15 parts of Flos Caryophyllis, 15 parts of Fructus Amomis, 20 parts of Semen Alpiniae Katsumadai, 30 parts of Endothelium Corneum Gigeriae Galli, 100 parts of Radix Astragali, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Rhizoma Dioscoreaes, 30 parts of Radix Codonopsis, 15 parts of Fructus Cannabiss.
5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
7. the application of the described any Chinese medicine composition of claim 1～6 in preparation treatment bowelcancer medicine.
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