CN111297428A - 用于栓塞植入物分离的系统和方法 - Google Patents

用于栓塞植入物分离的系统和方法 Download PDF

Info

Publication number
CN111297428A
CN111297428A CN201911274761.5A CN201911274761A CN111297428A CN 111297428 A CN111297428 A CN 111297428A CN 201911274761 A CN201911274761 A CN 201911274761A CN 111297428 A CN111297428 A CN 111297428A
Authority
CN
China
Prior art keywords
delivery tube
introducer sheath
length
proximal end
distal end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201911274761.5A
Other languages
English (en)
Other versions
CN111297428B (zh
Inventor
D.布卢门斯蒂克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Synthes Products Inc
Original Assignee
DePuy Synthes Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy Synthes Products Inc filed Critical DePuy Synthes Products Inc
Publication of CN111297428A publication Critical patent/CN111297428A/zh
Application granted granted Critical
Publication of CN111297428B publication Critical patent/CN111297428B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00778—Operations on blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/011—Instruments for their placement or removal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M2025/0079—Separate user-activated means, e.g. guidewires, guide tubes, balloon catheters or sheaths, for sealing off an orifice, e.g. a lumen or side holes, of a catheter

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

本发明题为“用于栓塞植入物分离的系统和方法”。提供了一种动脉瘤治疗系统，其包括栓塞植入物、递送系统和导引器护套，该导引器护套被共同设计成使得导引器护套和递送系统的组合可用作栓塞植入物的部署设备。递送系统可具有拉线、递送管和干预特征部，该干预特征部附接到拉线并定位在递送管的近端附近。导引器护套可在递送管之上朝近侧移动，直到其接合干预特征部，而不是被丢弃。为了部署植入物，可将导引器护套抵靠干预特征部按压，从而使干预特征部相对于递送管朝近侧移动，从而朝近侧牵拉干预特征部附接到其上的拉线并部署植入物。

Description

用于栓塞植入物分离的系统和方法
技术领域
本发明整体涉及动脉瘤治疗装置，并且更具体地涉及用于栓塞植入物的递送系统。
背景技术
许多血管内植入物装置是本领域已知的。许多经由将一个或多个导管和线材组合用于递送的系统来机械地部署。可被机械地递送的植入物的示例包括栓塞元件、支架、移植物、药物递送植入物、流动转向器、过滤器、刺激引线、感测引线或通过微导管递送的其他可植入结构。一些产科和胃肠道植入物也可经由将一根或多根导管和线材组合的类似系统植入。可通过机械装置释放或部署的装置在设计上差别很大，但可采用类似的递送导管和线材系统。许多此类基于导管的递送系统包括用于将植入物保持在导管中直到释放装置的时间的线材。然后，通过将线材相对于导管回缩或牵拉来致动这些系统。此类线材在本文中被称为“拉线”。
为了朝近侧牵拉该拉线以部署植入物，医师可使用许多已知部署设备中的一个。此类机械部署设备通常与递送系统分开并且具有用于夹持拉线并且用于朝近侧移动拉线的移动部件。不需要辅助部件和/或复杂移动零件的部署方法和设备可简化治疗规程并降低成本。因此，需要简化的机械植入物部署设备。
发明内容
本文公开了可解决上述需要的本发明的各种示例性系统、装置和方法。示例通常可包括栓塞植入系统，其包括栓塞植入物、递送系统和导引器护套，该导引器护套被共同设计成使得导引器护套和递送系统的组合可用作栓塞植入物的部署设备。递送系统可具有拉线、递送管和干预特征部，该干预特征部附接到拉线并定位在递送管的近端处。导引器护套可在递送管之上朝近侧移动，直到其接合干预特征部。为了部署植入物，可将导引器护套抵靠干预特征部按压，从而使干预特征部相对于递送管朝近侧移动，从而朝近侧牵拉干预特征部附接到其上的拉线并部署植入物。
示例性植入系统可包括递送管、栓塞线圈、导引器护套、干预特征部和细长构件。栓塞线圈可以可分离地附接到递送管的远端。干预特征部可定位在递送管的近端处并且可相对于递送管移动。细长构件可定位在递送管的管腔内并附接到干预特征部。导引器护套可具有尺寸被设定成可滑动地接纳递送管和栓塞线圈的管腔，导引器护套可在递送管之上从递送管的远端平移到递送管的近端，并且导引器护套的尺寸可被设定成接合干预特征部。干预特征部可响应于由导引器护套抵靠干预特征部施加的力而相对于递送管移动。细长构件可响应于干预特征部的近侧移动而相对于递送管移动。
干预特征部可与递送管分离。细长构件可响应于所分离的干预特征部的近侧移动而移动以离开递送管的近端。
递送管可在递送管的远端附近具有软节段。如从未植入的栓塞线圈的远端至软节段的近端测量的栓塞线圈和软节段的长度可短于导引器护套的端部至端部长度，使得导引器护套的尺寸被设定成完全包围未植入的栓塞线圈和软节段。导引器护套可比栓塞线圈和软节段的长度长约5cm。
系统可包括微导管，并且递送管可具有比导引器护套的端部至端部长度和微导管的端部至端部长度之和长的端部至端部长度。
导引器护套的端部至端部长度可介于约46cm至约105cm之间。
导引器护套可从封装构型移动到部署构型，在封装构型中，导引器护套被定位成完全包围软节段和栓塞线圈，在部署构型中，导引器护套与干预特征部接合。
栓塞线圈可通过使细长构件相对于递送管朝近侧移动而与递送管分离。
干预特征部可具有被定位成接合导引器护套的近端的基本上圆形的表面。
导引器护套的远端的尺寸可被设定成接合微导管以形成封闭接口，栓塞线圈和递送管的至少一部分可穿过该封闭接口。
示例性植入组件可包括递送管、栓塞植入物、拉线、接合隆起部和管状护套。栓塞植入物可附接到递送管的远端。拉线可设置在递送管的管腔内并且可移动以将栓塞植入物与递送管分离。接合隆起部可设置在拉线的近端上并且定位在递送管的近端附近。管状护套可在栓塞植入物和递送管之上从栓塞植入物的远端传输到递送管的近端，并且管状护套的尺寸可被设定成接合该接合隆起部。接合隆起部和拉线可响应于由管状护套施加到接合隆起部的力而相对于递送管移动。
递送管可具有从递送管的远端朝近侧延伸的软节段，并且当栓塞植入物附接到递送管并且以未植入构型延伸时，管状护套可将端部至端部长度测量为比从栓塞植入物的远端至软节段的近端测量的长度长约5cm。
组件可包括微导管，并且递送管可具有大于导引器护套和微导管的长度之和的端部至端部长度。
管状护套可从封装构型移动到部署构型，在封装构型中，管状护套被定位成完全包围软节段和栓塞线圈，在部署构型中，管状护套与接合隆起部接合。
接合隆起部可响应于由管状护套施加到接合隆起部的力而与递送管分离。拉线可响应由管状护套施加到接合隆起部的力而移动以将栓塞植入物与递送管分离。
一种用于治疗动脉瘤的示例性方法可包括提供植入系统的步骤，该植入系统包括栓塞植入物、导引器护套、递送管、干预特征部和拉线；将拉线附连到干预特征部；将拉线定位在递送管的管腔内；将干预特征部附接到递送管的近端；将栓塞植入物附接在递送管的远端处；将导引器护套定位成包围栓塞植入物和递送管的第一部分；将导引器护套在递送管之上朝近侧滑动；朝近侧牵拉导引器护套以将力从导引器护套施加到干预特征部；以及使干预特征部和拉线响应于该力而相对于递送管朝近侧移动。
在示例性方法中，导引器护套定位在其之上的递送管的第一部分可具有软节段。该方法可包括对导引器护套设定尺寸以具有比栓塞植入物和软节段的长度大约5cm的长度。该方法可包括对导引器护套设定尺寸以具有介于约46cm至约105cm之间的长度，该长度可从导引器护套的远端至近端测量。
该方法可包括响应于使干预特征部和拉线相对于递送管朝近侧移动而将栓塞植入物与递送管分离。该方法可包括将干预特征部与递送管分离。干预特征部可响应于使干预特征部和拉线相对于递送管朝近侧移动而分离。
该方法可包括提供微导管；将导引器护套定位成与微导管接合，同时将栓塞植入物和递送管的第一部分保持在导引器护套内；以及将栓塞植入物和递送管朝远侧平移，以将栓塞植入物和递送管的第一部分定位在微导管内。
附图说明
将参考下面的描述并结合附图进一步讨论本发明的上述及其它方面，
在这些附图中，相同的编号指示各种图中相同的结构元件和特征。附图未必按比例绘制，相反，将重点放在示出本发明的原理。附图仅以举例方式而非限制方式描绘了本发明装置的一种或多种具体实施。
图1是根据本发明的方面的示例性植入系统的图示；
图2A和图2B是根据本发明的方面的诸如图1所示的示例性植入系统与微导管相接的图示；
图3A至图3C是根据本发明的方面的可利用诸如图1所示的示例性植入系统执行的植入步骤的图示；
图4A示出了根据本发明的方面的具有可断裂的断开特征部的示例性植入系统；
图4B示出了如图4A所示且根据本发明的方面的图4A的示例性植入系统的近端附近的剖视图；
图5A示出了根据本发明的方面的具有旋锁式断开特征部的示例性植入系统；
图5B示出了如图5A所示且根据本发明的方面的图5A的示例性植入系统的近端附近的剖视图；
图6A示出了根据本发明的方面的具有滑动轨道的示例性植入系统；
图6B示出了如图6A所示且根据本发明的方面的图6A的示例性植入系统的近端附近的剖视图；
图7A示出了根据本发明的方面的具有可拉伸区段的示例性植入系统；
图7B示出了如图7A所示且根据本发明的方面的图7A的示例性植入系统的近端附近的剖视图；
图8A至图8C示出了根据本发明的方面的具有可拉伸区段和断开特征部的示例性植入系统的剖开视图；并且
图9示出了本领域已知的递送系统、微导管和导引器护套的相对尺寸。
具体实施方式
本文所呈现的示例利用导引器护套以有利于植入物的机械部署。可被机械地递送的植入物的示例包括栓塞元件、支架、移植物、药物递送植入物、流动转向器、过滤器、刺激引线、感测引线或可通过微导管递送的其他可植入结构。一些植入物当前被封装有导引器护套，该导引器护套在植入规程即将开始时从装置移除并丢弃。例如，在现有系统中，栓塞线圈和其他栓塞植入物在多种医疗应用中可用于闭塞血管。在许多情况下，在植入之前和在患者体外的栓塞植入物的处理期间，栓塞植入物被容纳在导引器护套中。在本发明的治疗实践中，一旦将栓塞植入物转移到微导管，就将导引器护套在栓塞植入物到达治疗部位之前从递送系统移除并丢弃。在本文所呈现的示例中，根据本发明，导引器护套可朝近侧滑动，并且可有利于栓塞植入物的部署，即栓塞植入物与递送系统的分离，而不是被丢弃。为了使用导引器护套以有利于部署，递送系统可具有定位在递送管的近端处并附接到拉线的干预特征部，并且导引器护套、递送管、拉线和干预特征部的组合可被构造成使得导引器护套可与干预特征部接合并且使干预特征部相对于递送管朝近侧移动，从而朝近侧牵拉拉线并且部署栓塞植入物。递送管、微导管和导引器护套可各自具有相应的长度，其尺寸被设定成使得导引器护套可足够长以覆盖递送系统的栓塞植入物和敏感部分，并且递送管可足够长以延伸穿过微导管的整个长度和导引器护套的整个长度。
图1为示例性植入系统100的图示。植入系统100可具有栓塞植入物140，诸如栓塞线圈、栓塞编织物或用于填充动脉瘤囊的其他此类植入物；递送管110，该递送管用于将栓塞植入物140递送到治疗部位；拉线130，该拉线设置在递送管内，可朝近侧牵拉该拉线以部署栓塞植入物140；干预特征部120，该干预特征部定位递送管110的近端112处，附接到拉线130，可朝近侧牵该干预特征部以朝近侧牵拉拉线130；和导引器护套180，该导引器护套可朝近侧移动以接合干预特征部120并朝近侧牵拉干预特征部120。
导引器护套180可具有穿过其的管腔，该管腔的尺寸被设定成可滑动地接纳递送管110和栓塞植入物140。导引器护套180的尺寸可被设定成使得其可在递送管110的长度之上从图1所示的位置朝近侧平移，以接合定位在递送管110的近端112处的干预特征部120。
干预特征部120可相对于递送管110移动。例如，干预特征部120可以可分离地附接到递送管110的近端112，并且系统100可包括断开特征部122，该断开特征部可被解钩、撕裂、断裂、扭转或以其他方式操纵以将干预特征部120与递送管110断开连接。
递送管110可具有定位在递送管110的远端114附近的软节段116，该软节段具有比递送管110的其余部分(近侧部分)118更大的柔韧性。栓塞植入物140可以可分离地附接到递送管114的远端114。软节段116可被设计成允许在植入和部署栓塞植入物140期间对递送管110的远端114进行更大的控制和稳定。软节段116可具有激光切割凹口或凹槽，和/或软节段116可由与递送管110的其余部分118相比更具柔性的材料制成。
当系统100在患者治疗规程之前和开始时被处理时，导引器护套180可用于保护(封装)栓塞植入物140和递送管110的软节段116的目的。为此目的，因此期望导引器护套180足够长以在治疗规程之前完全包围栓塞植入物140和软节段116。栓塞植入物140和软节段116的组合长度可从栓塞植入物140的远端144至软节段116的近端117测量。导引器护套180可具有可从导引器护套的远端184至近端182测量的长度，该长度的尺寸可被设定成比栓塞植入物140和软节段116的组合长度长几厘米，以确保栓塞植入物140和软节段116在治疗规程之前的处理期间在系统100的部分移位的情况下仍受保护。导引器护套180可具有比栓塞植入物140和软节段116的组合长度长约5cm的长度。例如，栓塞植入物140可具有介于约1cm和约60cm之间的长度，软节段116可具有约40cm的长度，并且导引器护套可具有比栓塞植入物140长度和软节段116长度之和长约5cm(即介于约46cm和约105cm之间)的长度。
图2A和图2B是诸如图1所示的示例性植入系统与微导管200相接的图示。图2A示出了在治疗规程即将开始时的治疗规程的某一时刻，其中导引器护套180被定位成以封装构型覆盖栓塞植入物140和递送管110的软节段116，并且导引器护套180的远端184与微导管200的近端配合或接合。如图2A所示，导引器护套180的远端184的尺寸可被设定成接合微导管200以形成封闭接口，栓塞植入物140和递送管110的软节段116可穿过该封闭接口。栓塞植入物140和递送管110可朝远侧平移以将栓塞植入物140和递送管110的一部分推入微导管200中。
图2B示出了其中栓塞植入物140和软节段116定位在微导管200内的治疗规程的某一时刻。在图2B所示的时刻下，栓塞植入物140和软节段116被微导管200保护，并且当将递送管110和栓塞植入物140进一步朝远侧平移时，导引器护套180现在可朝近侧牵拉或留在适当位置。
图3A至图3C是在一系列示例性植入步骤期间的示例性植入系统的图示。图3A示出了定位在微导管200内部的栓塞植入物140和递送管110的软节段116以及在递送管110的近侧部分118之上朝近侧平移的导引器护套180。如图3A所示，一旦栓塞植入物140和软节段116被保护在微导管200内，但在栓塞植入物140定位在治疗部位处或动脉瘤内之前，导引器护套180就可与微导管200脱离接合并朝近侧牵拉。另选地，导引器护套180可保持接合到微导管，直到栓塞植入物140定位在治疗部位或准备由递送管110部署，然后在栓塞植入物140定位在治疗部位之后朝近侧牵拉。
图3B示出了处于部署构型的导引器护套180，其中导引器护套180与定位在递送管110的近端112附近的干预特征部120接合。导引器护套180被示出为提供抵靠干预特征部120的力F。该力可足以使干预特征部120相对于递送管110朝近侧移动。在施加力F之前，干预特征部120可以可分离地附接到递送管110的近端112，并且干预特征部120可响应于力F而与递送管110的近端112分离。另选地，干预特征部120可保持附接到递送管110，并且力F可足以使干预特征部120相对于递送管110移动。
导引器护套180的尺寸可被设定成接合干预特征部120。如图所示，导引器护套180可为管状的并且可具有圆形近端182，并且干预特征部120可径向突起超过递送管110的圆周。干预特征部120可为圆形的，其具有的圆周大于导引器护套180的近端182的圆周。干预特征部120可提供平坦表面，导引器护套180的近端182可抵靠该平坦表面按压。除此之外或另选地，干预特征部可具有非平坦表面，该非平坦表面可具有用于接纳导引器护套180的斜坡或凹槽。干预特征部120可为定位在递送管的远端附近的隆起部，该隆起部延伸超过递送管的圆周并延伸成使得导引器护套180当在递送管110之上朝近侧滑动时必须在完全滑过和离开递送管110的近端112之前接合干预特征部120。
图3C示出了响应于来自导引器护套180的力F而相对于递送管110朝近侧移动之后的干预特征部120。干预特征部120可附接到拉线130，并且当干预特征部180朝近侧移动时，拉线130可朝近侧牵拉。干预特征部120可在干预特征部120的近侧移动之前可分离地附接到递送管110，并且可操纵分离特征部122以有利于干预特征部120的分离。一旦分离，就可将干预特征部120朝近侧牵拉远离递送管110，并且拉线130可响应于干预特征部120的牵拉而移动以离开递送管110的近端112。拉线130可为细长构件，其穿过递送管110的管腔朝栓塞植入物140延伸。拉线130可构成用于在递送管110的远端114处释放栓塞植入物140的部署系统的部件。当将拉线130朝近侧牵拉时，拉线130可启动栓塞植入物140的部署。栓塞植入物140可响应于拉线130相对于递送管110的近侧移动而与递送管110分离。
图4A示出了具有可断裂的断开特征部122a的示例性植入系统。该植入系统可具有由可断裂的断开特征部122a可分离地附接到递送管110的干预特征部120。递送管110可包括凹口115，该凹口为其中材料从递送管110移除的区域。凹口115可定位在递送管110的近端112处。递送管110的近端112可通过胶粘、焊接或其他方式附接到干预特征部120。凹口115可为递送管110的可断裂节段122a。当导引器护套180抵靠干预特征部120按压时，来自干预特征部120的力可导致可断裂节段122a断裂，并且随后可使干预特征部120相对于递送管110朝近侧移动。干预特征部120可具有圆形表面124，导引器护套180可抵靠该圆形表面按压。图4B为如图4A所示的示例性植入系统的近端附近的剖视图。
图5A示出了具有旋锁式断开特征部122a的示例性植入系统。该植入系统可具有递送管110，该递送管具有在近端112处割成的凹槽113和具有隆起部123或可接合凹槽113的另一特征部的干预特征部120。干预特征部120可通过旋锁式断开特征部(和/或卡口连接器)122b可分离地附接到递送管110。干预特征部120可在递送管110的近端112处延伸到递送管110的管腔内，并且具有隆起部或突起部123，所述隆起部或突起部可定位在递送管110中的凹槽113中以保持干预特征部120和递送管110之间的附接。隆起部或突起部123可滑动穿过凹槽113以将干预特征部120与递送管110分离。凹槽113可为L形，并且干预特征部120可相对于递送管110扭转，然后相对于递送管110朝近侧牵拉以断开旋锁式断开特征部122b。图5B示出了如图5A所示的示例性植入系统的近端附近的剖视图。
虽然图4A至图5B示出了在与递送管110分离之后可相对于递送管110移动的干预特征部120的示例，该干预特征部无需分离，并且可相对于递送管110移动而不分离。图6A至图8C示出了其中干预特征部120保持至少部分地附接到递送管110的示例性系统。
图6A示出了具有滑动轨道113a和隆起部或突起部123a的示例性植入系统。滑动轨道113a可在递送管110的近端112附近从递送管110的一部分割成。干预特征部120可具有定位成在轨道113a内滑动的接合隆起部或突起部123a。轨道113a可沿递送管110的长度的一部分延伸，并且隆起部123a可在轨道113a内滑动，从而允许干预特征部120相对于递送管110在近侧方向上移动。轨道113a可为L形，并且干预特征部120可相对于递送管110扭转，然后相对于递送管110朝近侧牵拉，以使干预特征部120相对于递送管110移动。干预特征部120可附接到拉线130，并且干预特征部120的移动可使拉线130移动以部署栓塞植入物140。图6B示出了如图6A所示的示例性植入系统的近端附近的剖视图。
图7A示出了具有可拉伸区段126的示例性植入系统。该植入系统可具有递送管110，该递送管具有定位在递送管110的近端112附近的可拉伸区段126。可拉伸区段126可为递送管110的区域，所述区域具有响应于沿递送管110的包括可拉伸区段126的长度产生张力的力而拉伸的倾向。可拉伸区段126可包括在初始状态下被压缩的线圈，如图7A所示，管的激光切割部分和/或具有较大弹性的管材的一部分。可拉伸区段126可响应于由导引器护套180提供的抵靠干预特征部120的力而延伸。可拉伸区段126可允许拉线和干预特征部120相对于递送管110朝近侧移动，而不会使干预特征部120与递送管110断开连接。可拉伸区段126可具有由可拉伸区段126的材料特性和/或构造确定的完全延伸长度。完全延伸长度可限制干预特征部120可相对于递送管110朝近侧移动的距离。图7B示出了如图7A所示的示例性植入系统的近端附近的剖视图。
图8A至图8C示出了具有可拉伸元件126a和分离特征部122c的示例性植入系统。图8A至图8C示出了断开特征部122c可包括递送管110中的凹口115B，类似于图4和图4B所示的凹口。可以设想，其他断开特征部(包括图1、3A-3C、5或5B所示和相对于其所述的断开特征部)可与如本文所述的那些或换句话讲已知的那些可拉伸区段组合。当与可拉伸区段126a结合地使用时，断开特征部122c可沿递送管110的长度定位在可拉伸区段126a处或附近。可拉伸区段126a和断开特征部122c两者均可定位在递送管110的近端112附近。
图8A示出了可拉伸元件126a，该可拉伸元件在递送管110的近端112附近定位在递送管110的管腔内。在图8A中，递送管110被示出为剖开的以示出其内可拉伸元件126a的线圈。在图8A所示的构型中，干预特征部120可经由可拉伸元件126a和分离特征部122c附接到递送管110。
图8B示出了朝近侧移动以接合干预特征部120，断裂分离特征部122c并开始拉伸可拉伸元件126a的导引器护套180。递送管110和导引器护套180被示出为剖开的。拉线130可定位在递送管110内。当干预特征部130朝近侧移动时，拉线120可朝近侧牵拉。可拉伸元件126a可利用焊接、粘合剂或其他连接125附接到干预特征部120。可拉伸元件126a可利用焊接、粘合剂或其他连接127附接到递送管110。在分离特征部122c分离之后，可拉伸元件126a可保持干预特征部120和递送管110之间的附接。
图8C示出了导引器护套180进一步朝近侧移动以使干预特征部120和拉线130进一步朝近侧移动，并且进一步拉伸可拉伸元件126a。可拉伸元件126a可具有由可拉伸元件126a的材料特性和/或构造确定的完全延伸长度。完全延伸长度可限制干预特征部120可相对于递送管110朝近侧移动的距离。
图9示出了本领域已知的递送系统、微导管和导引器护套的相对尺寸。已知的递送系统通常为200cm长，已知的微导管通常为165cm长，并且已知的导引器护套通常为130cm长。在已知的实践中，导引器护套通常在栓塞植入物和递送系统的任何敏感部分插入微导管之后被移除。根据已知的实践，在栓塞植入物的部署步骤期间，导引器护套不能保持围绕递送系统，因为已知微导管和导引器的组合长度比已知递送系统长几厘米。本发明的一个方面是设定递送系统和导引器护套的尺寸，使得导引器护套可通过栓塞植入物部署步骤保持在递送系统上。在本文提供的示例性系统中，植入系统可包括递送系统、微导管和导引器护套，其中递送系统比微导管和导引器护套的组合长度长。
动脉瘤可用植入系统(诸如本文关于本发明所公开的植入系统中的任一种)通过以下方式进行治疗：执行以下步骤中的一些或全部步骤，不一定按顺序。可提供植入系统100，该植入系统具有栓塞植入物140、导引器护套180、递送管110、干预特征部120和拉线130。拉线130可附连到干预特征部120。拉线130可定位在递送管110的管腔内。干预特征部120可附接到递送管110的近端112。栓塞植入物140可附接在递送管110的远端114处。导引器护套180可被定位成包围栓塞植入物140和递送管110的第一部分。递送管110的第一部分可包括软节段116。导引器护套的尺寸可被设定成具有比可从栓塞植入物140的远端144至软节段116的近端117测量的长度长约5cm的端部至端部长度。导引器护套180的尺寸可被设定成使得端部至端部长度介于约46cm和约105cm之间。可提供微导管200。导引器护套180可被定位成与微导管200接合，同时将栓塞植入物140和递送管110的第一部分保持在导引器护套180内。栓塞植入物140和递送管110可朝远侧平移，以将栓塞植入物140和递送管110的第一部分定位在微导管200内。导引器护套180可在递送管110之上朝近侧滑动。导引器护套180可朝近侧牵拉以将力从导引器护套180施加到干预特征部120。干预特征部120和拉线130可响应于力而相对于递送管110朝近侧移动。干预特征部120可与递送管110分离。栓塞植入物140可响应于使干预特征部120和拉线130相对于递送管110朝近侧移动而与递送管110分离。
本文所包含的描述是本发明的实施方案的示例，并且不旨在以任何方式限制本发明的范围。如本文所述，本发明设想了植入系统和相关方法的许多变型和修改，包括系统部件的另选几何形状、另选材料、附加的或另选的方法步骤等。这些修改对于本发明所属领域的普通技术人员将是显而易见的，并且旨在处于以下权利要求书的范围内。

Claims (20)

1.一种植入系统，包括：
递送管，所述递送管包括穿过其的管腔、近端和远端；
栓塞线圈，所述栓塞线圈可分离地附接到所述递送管的所述远端；
导引器护套，所述导引器护套包括穿过其的管腔，所述管腔的尺寸被设定成可滑动地接纳所述递送管和所述栓塞线圈；
干预特征部，所述干预特征部接近所述递送管的所述近端定位；和
细长构件，所述细长构件设置在所述递送管的所述管腔内并且附接到所述干预特征部，
其中所述导引器护套能够在所述递送管之上从所述递送管的所述远端平移到所述递送管的所述近端，并且其尺寸被设定成接合所述干预特征部，
其中所述干预特征部能够响应于由所述导引器护套抵靠所述干预特征部施加的力而相对于所述递送管移动，并且
其中所述细长构件能够响应于所述干预特征部的近侧移动而相对于所述递送管移动。
2.根据权利要求1所述的系统，其中所述干预特征部能够与所述递送管分离，并且其中所述细长构件能够响应于所分离的干预特征部的近侧移动而移动以离开所述递送管的所述近端。
3.根据权利要求1所述的系统，
其中所述递送管包括接近所述递送管的所述远端设置的软节段，
其中第一长度能够从所述栓塞线圈的远端至所述软节段的近端测量，并且
其中所述导引器护套包括能够从所述导引器护套的远端至近端测量的第二长度，所述第二长度测量为比所述第一长度大约5cm。
4.根据权利要求3所述的系统，还包括微导管，所述微导管包括能够从所述微导管的远端至近端测量的第三长度，并且其中所述递送管包括能够从所述递送管的所述远端至所述近端测量的第四长度，所述第四长度测量为大于所述第三长度和所述第二长度之和。
5.根据权利要求1所述的系统，其中所述导引器护套包括介于约46cm至约105cm之间的长度，所述长度能够从所述导引器护套的远端至近端测量。
6. 根据权利要求1所述的系统，
其中所述递送管包括接近所述递送管的所述远端设置的软节段，并且
其中所述导引器护套能够从封装构型移动到部署构型，在所述封装构型中，所述导引器护套被定位成完全包围所述软节段和所述栓塞线圈，在所述部署构型中，所述导引器护套与所述干预特征部接合。
7.根据权利要求1所述的系统，其中所述栓塞线圈能够响应于所述细长构件相对于所述递送管的近侧移动而与所述递送管分离。
8.根据权利要求1所述的系统，其中所述干预特征部包括被定位成接合所述导引器护套的所述近端的基本上圆形的表面。
9.一种植入组件，包括：
递送管，所述递送管包括穿过其的管腔、近端和远端；
栓塞植入物，所述栓塞植入物附接到所述递送管的所述远端；
拉线，所述拉线设置在所述递送管的所述管腔内并且能够移动以将所述栓塞植入物与所述递送管分离；
接合隆起部，所述接合隆起部设置在所述拉线的近端上并且接近所述递送管的所述近端定位；和
管状护套，所述管状护套能够在所述栓塞植入物和所述递送管之上从所述栓塞植入物的远端传输到所述递送管的所述近端，所述管状护套的尺寸被设定成接合所述接合隆起部，
其中所述接合隆起部和所述拉线能够响应于由所述管状护套施加到所述接合隆起部的力而相对于所述递送管移动。
10.根据权利要求9所述的组件，
其中所述递送管包括从所述递送管的所述远端朝近侧延伸的软节段，
其中第一长度能够从所述栓塞植入物的所述远端至所述软节段的近端测量，并且
其中所述管状护套包括能够从所述管状护套的远端至近端测量的第二长度，所述第二长度测量为比所述第一长度大约5cm。
11.根据权利要求10所述的组件，还包括微导管，所述微导管包括能够从所述微导管的远端至近端测量的第三长度，并且其中所述递送管包括能够从所述递送管的所述远端至所述递送管的所述近端测量的第四长度，所述第四长度测量为大于所述第三长度和所述第二长度之和。
12. 根据权利要求9所述的组件，
其中所述递送管包括从所述递送管的所述远端朝近侧延伸的软节段，并且
其中所述管状护套能够从封装构型移动到部署构型，在所述封装构型中，所述管状护套被定位成完全包围所述软节段和所述栓塞线圈，在所述部署构型中，所述管状护套与所述接合隆起部接合。
13.根据权利要求9所述的组件，其中所述接合隆起部能够响应于由所述管状护套施加的所述力而与所述递送管分离。
14.根据权利要求9所述的组件，其中所述拉线能够响应于由所述管状护套施加的所述力而移动以将所述栓塞植入物与所述递送管分离。
15.一种用于治疗动脉瘤的方法，包括：
提供植入系统，所述植入系统包括栓塞植入物、导引器护套、递送管、干预特征部和拉线；
将所述拉线附连到所述干预特征部；
将所述拉线定位在所述递送管的管腔内；
将所述干预特征部附接到所述递送管的近端；
将所述栓塞植入物附接在所述递送管的远端处；
将所述导引器护套定位成包围所述栓塞植入物和所述递送管的第一部分；
将所述导引器护套在所述递送管之上朝近侧滑动；
朝近侧牵拉所述导引器护套以将力从所述导引器护套施加到所述干预特征部；以及
使所述干预特征部和所述拉线响应于所述力而相对于所述递送管朝近侧移动。
16. 根据权利要求15所述的方法，
其中所述递送管的所述第一部分包括软节段，并且
其中第一长度能够从所述栓塞植入物的远端至所述软节段的近端测量，
所述方法还包括对所述导引器护套设定尺寸以包括能够从所述导引器护套的远端至近端测量的第二长度，所述第二长度测量为比所述第一长度大约5cm。
17.根据权利要求15所述的方法，还包括对所述导引器护套设定尺寸以包括介于约46cm至约105cm之间的长度，所述长度能够从所述导引器护套的远端至近端测量。
18.根据权利要求15所述的方法，还包括响应于使所述干预特征部和所述拉线相对于所述递送管朝近侧移动而将所述栓塞植入物与所述递送管分离。
19.根据权利要求15所述的方法，还包括将所述干预特征部与所述递送管分离。
20.根据权利要求15所述的方法，还包括：
提供微导管；
将所述导引器护套定位成与所述微导管接合，同时将所述栓塞植入物和所述递送管的所述第一部分保持在所述导引器护套内；以及
将所述栓塞植入物和所述递送管朝远侧平移，以将所述栓塞植入物和所述递送管的所述第一部分定位在所述微导管内。
CN201911274761.5A 2018-12-12 2019-12-12 用于栓塞植入物分离的系统和方法 Active CN111297428B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/218,342 US11147562B2 (en) 2018-12-12 2018-12-12 Systems and methods for embolic implant detachment
US16/218342 2018-12-12

Publications (2)

Publication Number Publication Date
CN111297428A true CN111297428A (zh) 2020-06-19
CN111297428B CN111297428B (zh) 2024-06-18

Family

ID=68886885

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911274761.5A Active CN111297428B (zh) 2018-12-12 2019-12-12 用于栓塞植入物分离的系统和方法

Country Status (6)

Country Link
US (1) US11147562B2 (zh)
EP (1) EP3666202B1 (zh)
JP (1) JP7412997B2 (zh)
KR (1) KR20200072433A (zh)
CN (1) CN111297428B (zh)
ES (1) ES2901928T3 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114081568A (zh) * 2021-11-19 2022-02-25 心凯诺医疗科技(上海)有限公司 一种栓塞材料及其输送系统

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9918718B2 (en) 2014-08-08 2018-03-20 DePuy Synthes Products, Inc. Embolic coil delivery system with retractable mechanical release mechanism
US10806462B2 (en) 2017-12-21 2020-10-20 DePuy Synthes Products, Inc. Implantable medical device detachment system with split tube and cylindrical coupling
US11147562B2 (en) 2018-12-12 2021-10-19 DePuy Synthes Products, Inc. Systems and methods for embolic implant detachment
US11253265B2 (en) 2019-06-18 2022-02-22 DePuy Synthes Products, Inc. Pull wire detachment for intravascular devices
US11207494B2 (en) 2019-07-03 2021-12-28 DePuy Synthes Products, Inc. Medical device delivery member with flexible stretch resistant distal portion
US11426174B2 (en) 2019-10-03 2022-08-30 DePuy Synthes Products, Inc. Medical device delivery member with flexible stretch resistant mechanical release
US11672946B2 (en) * 2019-09-24 2023-06-13 Boston Scientific Scimed, Inc. Protection and actuation mechanism for controlled release of implantable embolic devices
US11376013B2 (en) 2019-11-18 2022-07-05 DePuy Synthes Products, Inc. Implant delivery system with braid cup formation
US11457922B2 (en) 2020-01-22 2022-10-04 DePuy Synthes Products, Inc. Medical device delivery member with flexible stretch resistant distal portion
US11432822B2 (en) * 2020-02-14 2022-09-06 DePuy Synthes Products, Inc. Intravascular implant deployment system
US11951026B2 (en) 2020-06-30 2024-04-09 DePuy Synthes Products, Inc. Implantable medical device detachment system with flexible braid section
US11701123B2 (en) 2020-08-21 2023-07-18 Shape Memory Medical, Inc. Mechanical detachment system for transcatheter devices
KR20220130605A (ko) * 2021-03-18 2022-09-27 디퍼이 신테스 프로덕츠, 인코포레이티드 색전 이식체 분리를 위한 시스템 및 방법
US11844490B2 (en) 2021-12-30 2023-12-19 DePuy Synthes Products, Inc. Suture linkage for inhibiting premature embolic implant deployment
US11937824B2 (en) 2021-12-30 2024-03-26 DePuy Synthes Products, Inc. Implant detachment systems with a modified pull wire
US12011171B2 (en) 2022-01-06 2024-06-18 DePuy Synthes Products, Inc. Systems and methods for inhibiting premature embolic implant deployment
US11937825B2 (en) 2022-03-02 2024-03-26 DePuy Synthes Products, Inc. Hook wire for preventing premature embolic implant detachment
US11937826B2 (en) 2022-03-14 2024-03-26 DePuy Synthes Products, Inc. Proximal link wire for preventing premature implant detachment
US20230293184A1 (en) * 2022-03-15 2023-09-21 DePuy Synthes Products, Inc. Interference feature for inhibiting premature embolic implant detachment
TW202400089A (zh) * 2022-03-16 2024-01-01 美商西瑞维斯克公司 用於腦積水和顱內高壓的血管內治療的系統和方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060276829A1 (en) * 2005-06-02 2006-12-07 Keith Balgobin Stretch resistant embolic coil delivery system with mechanical release mechanism
US20080228215A1 (en) * 2007-03-13 2008-09-18 Micro Therapeutics, Inc. Implant including a coil and a stretch-resistant member
CN103099692A (zh) * 2011-09-27 2013-05-15 科德曼及舒特莱夫公司 用于血管装置的远端分离机构
US20140277093A1 (en) * 2013-03-14 2014-09-18 Stryker Nv Operations Limited Vaso-occlusive device delivery system
US20150182227A1 (en) * 2013-12-27 2015-07-02 Blockade Medical, LLC Coil system
US20180325706A1 (en) * 2015-01-20 2018-11-15 Neurogami Medical, Inc. Vascular implant

Family Cites Families (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429408A (en) 1967-04-25 1969-02-25 Associated Spring Corp Actuator sleeves for spring clutch
US5484409A (en) 1989-08-25 1996-01-16 Scimed Life Systems, Inc. Intravascular catheter and method for use thereof
US5122136A (en) 1990-03-13 1992-06-16 The Regents Of The University Of California Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
US5108407A (en) 1990-06-08 1992-04-28 Rush-Presbyterian St. Luke's Medical Center Method and apparatus for placement of an embolic coil
US5636639A (en) 1992-02-18 1997-06-10 Symbiosis Corporation Endoscopic multiple sample bioptome with enhanced biting action
US5263964A (en) 1992-05-06 1993-11-23 Coil Partners Ltd. Coaxial traction detachment apparatus and method
US5250071A (en) 1992-09-22 1993-10-05 Target Therapeutics, Inc. Detachable embolic coil assembly using interlocking clasps and method of use
US5350397A (en) 1992-11-13 1994-09-27 Target Therapeutics, Inc. Axially detachable embolic coil assembly
US5382259A (en) 1992-10-26 1995-01-17 Target Therapeutics, Inc. Vasoocclusion coil with attached tubular woven or braided fibrous covering
US5334210A (en) 1993-04-09 1994-08-02 Cook Incorporated Vascular occlusion assembly
US5925059A (en) 1993-04-19 1999-07-20 Target Therapeutics, Inc. Detachable embolic coil assembly
US5569221A (en) 1994-07-07 1996-10-29 Ep Technologies, Inc. Catheter component bond and method
US6273404B1 (en) 1995-06-05 2001-08-14 Scimed Life Systems, Inc. Method of making monolithic hub and strain relief
US6168622B1 (en) 1996-01-24 2001-01-02 Microvena Corporation Method and apparatus for occluding aneurysms
US5899935A (en) 1997-08-04 1999-05-04 Schneider (Usa) Inc. Balloon expandable braided stent with restraint
US6203547B1 (en) 1997-12-19 2001-03-20 Target Therapeutics, Inc. Vaso-occlusion apparatus having a manipulable mechanical detachment joint and a method for using the apparatus
US6113622A (en) 1998-03-10 2000-09-05 Cordis Corporation Embolic coil hydraulic deployment system
US6835185B2 (en) 1998-12-21 2004-12-28 Micrus Corporation Intravascular device deployment mechanism incorporating mechanical detachment
US6391037B1 (en) 2000-03-02 2002-05-21 Prodesco, Inc. Bag for use in the intravascular treatment of saccular aneurysms
US6623504B2 (en) 2000-12-08 2003-09-23 Scimed Life Systems, Inc. Balloon catheter with radiopaque distal tip
WO2002054943A2 (en) * 2001-01-10 2002-07-18 Cordis Neurovascular, Inc. Embolic coil introducer system
US6454780B1 (en) 2001-06-21 2002-09-24 Scimed Life Systems, Inc. Aneurysm neck obstruction device
US8715312B2 (en) 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
US8252040B2 (en) 2001-07-20 2012-08-28 Microvention, Inc. Aneurysm treatment device and method of use
US20030195553A1 (en) 2002-04-12 2003-10-16 Scimed Life Systems, Inc. System and method for retaining vaso-occlusive devices within an aneurysm
US7608058B2 (en) 2002-07-23 2009-10-27 Micrus Corporation Stretch resistant therapeutic device
US8425549B2 (en) 2002-07-23 2013-04-23 Reverse Medical Corporation Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US7208003B2 (en) * 2002-09-20 2007-04-24 Cordis Neurovascular, Inc. Reattachable introducer for a medical device deployment system
FR2853521B1 (fr) * 2003-04-10 2005-12-02 Claude Mialhe Dispositif de dilatation d'un vaisseau et introducteur d'implant vasculaire
US7371228B2 (en) 2003-09-19 2008-05-13 Medtronic Vascular, Inc. Delivery of therapeutics to treat aneurysms
US8182544B2 (en) 2003-10-08 2012-05-22 Codman & Shurtleff, Inc. Method for placing a medical agent into a vessel of the body
US9308382B2 (en) 2004-06-10 2016-04-12 Medtronic Urinary Solutions, Inc. Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US20060025801A1 (en) 2004-07-30 2006-02-02 Robert Lulo Embolic device deployment system with filament release
US9655633B2 (en) 2004-09-10 2017-05-23 Penumbra, Inc. System and method for treating ischemic stroke
EP1804719A2 (en) 2004-09-22 2007-07-11 Lee R. Guterman Cranial aneurysm treatment arrangement
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US20060116714A1 (en) 2004-11-26 2006-06-01 Ivan Sepetka Coupling and release devices and methods for their assembly and use
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7608089B2 (en) 2004-12-22 2009-10-27 Boston Scientific Scimed, Inc. Vaso-occlusive device having pivotable coupling
US20060206139A1 (en) 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US20060276826A1 (en) 2005-06-02 2006-12-07 Vladimir Mitelberg Stretch resistant embolic coil delivery system with mechanical release mechanism
US20060276833A1 (en) 2005-06-02 2006-12-07 Keith Balgobin Stretch resistant embolic coil delivery system with spring assisted release mechanism
US7371251B2 (en) 2005-06-02 2008-05-13 Cordis Neurovascular, Inc. Stretch resistant embolic coil delivery system with mechanical release mechanism
US7377932B2 (en) 2005-06-02 2008-05-27 Cordis Neurovascular, Inc. Embolic coil delivery system with mechanical release mechanism
US7819891B2 (en) 2005-06-02 2010-10-26 Codman & Shurtleff, Inc. Stretch resistant embolic coil delivery system with spring release mechanism
US20060276830A1 (en) 2005-06-02 2006-12-07 Keith Balgobin Stretch resistant embolic coil delivery system with mechanical release mechanism
US20060276825A1 (en) 2005-06-02 2006-12-07 Vladimir Mitelberg Stretch resistant embolic coil delivery system with mechanical release mechanism
US7819892B2 (en) 2005-06-02 2010-10-26 Codman & Shurtleff, Inc. Embolic coil delivery system with spring wire release mechanism
US7708754B2 (en) 2005-06-02 2010-05-04 Codman & Shurtleff, Pc Stretch resistant embolic coil delivery system with mechanical release mechanism
US7708755B2 (en) 2005-06-02 2010-05-04 Codman & Shurtleff Inc. Stretch resistant embolic coil delivery system with combined mechanical and pressure release mechanism
US7811305B2 (en) 2005-06-02 2010-10-12 Codman & Shurtleff, Inc. Stretch resistant embolic coil delivery system with spring release mechanism
US7985238B2 (en) 2005-06-02 2011-07-26 Codman & Shurtleff, Inc. Embolic coil delivery system with spring wire release mechanism
US7371252B2 (en) 2005-06-02 2008-05-13 Cordis Neurovascular, Inc. Stretch resistant embolic coil delivery system with mechanical release mechanism
US7799052B2 (en) * 2005-06-02 2010-09-21 Codman & Shurtleff, Inc. Stretch resistant embolic coil delivery system with mechanical release mechanism
US9636115B2 (en) 2005-06-14 2017-05-02 Stryker Corporation Vaso-occlusive delivery device with kink resistant, flexible distal end
EP2759276A1 (en) 2005-06-20 2014-07-30 Medtronic Ablation Frontiers LLC Ablation catheter
US20070083132A1 (en) 2005-10-11 2007-04-12 Sharrow James S Medical device coil
EP1973680B1 (en) 2005-11-17 2018-01-10 Microvention, Inc. Three-dimensional complex coil
US9757260B2 (en) 2006-03-30 2017-09-12 Medtronic Vascular, Inc. Prosthesis with guide lumen
US7766933B2 (en) 2006-03-31 2010-08-03 Codman & Shurtleff, Inc. Stretch resistant design for embolic coils with stabilization bead
US9615832B2 (en) 2006-04-07 2017-04-11 Penumbra, Inc. Aneurysm occlusion system and method
US8777979B2 (en) 2006-04-17 2014-07-15 Covidien Lp System and method for mechanically positioning intravascular implants
CN101500623B (zh) 2006-06-15 2016-08-24 微温森公司 一种由可膨胀聚合物构成的栓塞器械
US8366720B2 (en) 2006-07-31 2013-02-05 Codman & Shurtleff, Inc. Interventional medical device system having an elongation retarding portion and method of using the same
US8062325B2 (en) 2006-07-31 2011-11-22 Codman & Shurtleff, Inc. Implantable medical device detachment system and methods of using the same
US7901444B2 (en) 2006-09-29 2011-03-08 Codman & Shurtleff, Inc. Embolic coil delivery system with mechanical release mechanism
EP2088936A2 (en) 2006-11-20 2009-08-19 Boston Scientific Scimed, Inc. Mechanically detachable vaso-occlusive device
WO2008085606A1 (en) 2006-11-20 2008-07-17 Boston Scientific Scimed, Inc. Mechanically detachable vaso-occlusive device
WO2008074027A1 (en) 2006-12-13 2008-06-19 Biomerix Corporation Aneurysm occlusion devices
US8197442B2 (en) 2007-04-27 2012-06-12 Codman & Shurtleff, Inc. Interventional medical device system having a slotted section and radiopaque marker and method of making the same
EP2444010B1 (en) 2007-05-18 2017-03-01 Stryker European Holdings I, LLC Medical implant detachment systems
DE102007038446A1 (de) 2007-08-14 2009-02-19 pfm Produkte für die Medizin AG Embolisiereinrichtung
CA2709379C (en) 2007-12-21 2016-08-16 Microvention, Inc. Hydrogel filaments for biomedical uses
US8974518B2 (en) 2008-03-25 2015-03-10 Medtronic Vascular, Inc. Eversible branch stent-graft and deployment method
AU2009239424B9 (en) 2008-04-21 2014-10-09 Covidien Lp Braid-ball embolic devices and delivery systems
WO2009135083A1 (en) 2008-04-30 2009-11-05 Medtronic, Inc. Techniques for placing medical leads for electrical stimulation of nerve tissue
US20090312748A1 (en) 2008-06-11 2009-12-17 Johnson Kirk L Rotational detachment mechanism
US8070694B2 (en) 2008-07-14 2011-12-06 Medtronic Vascular, Inc. Fiber based medical devices and aspiration catheters
US8333796B2 (en) 2008-07-15 2012-12-18 Penumbra, Inc. Embolic coil implant system and implantation method
US9232992B2 (en) 2008-07-24 2016-01-12 Aga Medical Corporation Multi-layered medical device for treating a target site and associated method
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
JP5608731B2 (ja) 2009-04-15 2014-10-15 マイクロベンション インコーポレイテッド インプラント送達システム
EP2421482B1 (en) 2009-04-20 2019-11-13 Achieva Medical Limited Delivery assembly for occlusion device using mechanical interlocking coupling mechanism
US8758423B2 (en) 2009-06-18 2014-06-24 Graftcraft I Goteborg Ab Device and method for treating ruptured aneurysms
US8911487B2 (en) 2009-09-22 2014-12-16 Penumbra, Inc. Manual actuation system for deployment of implant
US20110202085A1 (en) 2009-11-09 2011-08-18 Siddharth Loganathan Braid Ball Embolic Device Features
CN102188300B (zh) * 2010-03-02 2014-05-28 上海微创医疗器械（集团）有限公司 一种动脉瘤手术装置
AU2011240927B2 (en) 2010-04-14 2015-07-16 Microvention, Inc. Implant delivery device
US8764811B2 (en) 2010-04-20 2014-07-01 Medtronic Vascular, Inc. Controlled tip release stent graft delivery system and method
US8876878B2 (en) 2010-07-23 2014-11-04 Medtronic, Inc. Attachment mechanism for stent release
US8616040B2 (en) 2010-09-17 2013-12-31 Medtronic Vascular, Inc. Method of forming a drug-eluting medical device
BR112013015437A2 (pt) 2010-12-20 2016-09-20 Microvention Inc stents poliméricos e métodos de fabricação
US20120283768A1 (en) 2011-05-05 2012-11-08 Sequent Medical Inc. Method and apparatus for the treatment of large and giant vascular defects
US9486604B2 (en) 2011-05-12 2016-11-08 Medtronic, Inc. Packaging and preparation tray for a delivery system
JP6026513B2 (ja) 2011-05-13 2016-11-16 スパイレーション インコーポレイテッド ディー ビー エイ オリンパス レスピラトリー アメリカ 展開カテーテル
WO2012158668A1 (en) 2011-05-17 2012-11-22 Stryker Corporation Method of fabricating an implantable medical device that includes one or more thin film polymer support layers
WO2012166467A1 (en) 2011-05-27 2012-12-06 Stryker Corporation Assembly for percutaneously inserting an implantable medical device, steering the device to a target location and deploying the device
US9750565B2 (en) 2011-09-30 2017-09-05 Medtronic Advanced Energy Llc Electrosurgical balloons
AU2013231845B2 (en) 2012-03-16 2017-07-06 Terumo Corporation Stent and stent delivery device
US9833625B2 (en) 2012-03-26 2017-12-05 Medtronic, Inc. Implantable medical device delivery with inner and outer sheaths
US9717421B2 (en) 2012-03-26 2017-08-01 Medtronic, Inc. Implantable medical device delivery catheter with tether
US9155540B2 (en) 2012-03-30 2015-10-13 DePuy Synthes Products, Inc. Embolic coil detachment mechanism with heating element and kicker
US9242290B2 (en) 2012-04-03 2016-01-26 Medtronic Vascular, Inc. Method and apparatus for creating formed elements used to make wound stents
US9549832B2 (en) 2012-04-26 2017-01-24 Medtronic Vascular, Inc. Apparatus and methods for filling a drug eluting medical device via capillary action
US9700399B2 (en) 2012-04-26 2017-07-11 Medtronic Vascular, Inc. Stopper to prevent graft material slippage in a closed web stent-graft
US9149190B2 (en) 2012-07-17 2015-10-06 Stryker Corporation Notification system of deviation from predefined conditions
US9770251B2 (en) 2012-08-13 2017-09-26 Microvention, Inc. Shaped removal device
US20140058435A1 (en) 2012-08-21 2014-02-27 Donald K. Jones Implant delivery and release system
US9504476B2 (en) 2012-10-01 2016-11-29 Microvention, Inc. Catheter markers
BR112015008245B1 (pt) 2012-10-15 2022-09-27 Microvention, Inc Composições poliméricas de tratamento
US20140135810A1 (en) 2012-11-13 2014-05-15 Covidien Lp Occlusive devices
US9539022B2 (en) 2012-11-28 2017-01-10 Microvention, Inc. Matter conveyance system
WO2014089392A1 (en) 2012-12-07 2014-06-12 Medtronic, Inc. Minimally invasive implantable neurostimulation system
US9943313B2 (en) 2013-01-03 2018-04-17 Empirilon Technology Llc Detachable coil release system and handle assembly
US10342546B2 (en) 2013-01-14 2019-07-09 Microvention, Inc. Occlusive device
US9539382B2 (en) 2013-03-12 2017-01-10 Medtronic, Inc. Stepped catheters with flow restrictors and infusion systems using the same
ES2879634T3 (es) 2013-03-14 2021-11-22 Stryker Corp Sistema de administración de dispositivo vasooclusivo
WO2014159584A2 (en) 2013-03-14 2014-10-02 Stryker Corporation Vaso-occlusive device delivery system
KR20150127200A (ko) 2013-03-14 2015-11-16 인큐메덱스, 아이엔씨. 환자의 혈관 질환부로 임플란트를 전달하기 위한 장치
EP2967605B1 (en) 2013-03-15 2019-12-18 Microvention, Inc. Multi-component obstruction removal system
CN110169802B (zh) 2013-03-15 2022-07-08 柯惠有限合伙公司 血管植入物的输送与分离机构
US9398966B2 (en) 2013-03-15 2016-07-26 Medtronic Vascular, Inc. Welded stent and stent delivery system
JP6636908B2 (ja) 2013-03-15 2020-01-29 テルモ株式会社 塞栓防止装置
ES2717678T3 (es) 2013-04-22 2019-06-24 Stryker European Holdings I Llc Procedimiento para la carga de fármacos sobre superficies de implantes recubiertos de hidroxiapatita
US9445928B2 (en) 2013-05-30 2016-09-20 Medtronic Vascular, Inc. Delivery system having a single handed deployment handle for a retractable outer sheath
US11291452B2 (en) 2013-06-26 2022-04-05 W. L. Gore & Associates, Inc. Medical device deployment system
US9662120B2 (en) 2013-08-23 2017-05-30 Cook Medical Technologies Llc Detachable treatment device delivery system utilizing compression at attachment zone
US9675782B2 (en) 2013-10-10 2017-06-13 Medtronic Vascular, Inc. Catheter pull wire actuation mechanism
US9439827B2 (en) 2013-10-25 2016-09-13 Medtronic Vascular, Inc. Tissue compression device with pressure indicator
KR102211335B1 (ko) 2013-12-20 2021-02-03 마이크로벤션, 인코포레이티드 장치 전달 시스템
WO2015095815A1 (en) 2013-12-20 2015-06-25 Microvention, Inc. Delivery adapter
US9788839B2 (en) 2014-02-14 2017-10-17 Cook Medical Technologies Llc Stable screw-type detachment mechanism
JP6154082B2 (ja) 2014-04-08 2017-06-28 ストライカー コーポレイションＳｔｒｙｋｅｒ Ｃｏｒｐｏｒａｔｉｏｎ インプラント送達システム
US20170049596A1 (en) 2014-04-30 2017-02-23 Stryker Corporation Implant delivery system and method of use
US9060777B1 (en) 2014-05-28 2015-06-23 Tw Medical Technologies, Llc Vaso-occlusive devices and methods of use
US9668898B2 (en) 2014-07-24 2017-06-06 Medtronic Vascular, Inc. Stent delivery system having dynamic deployment and methods of manufacturing same
ES2726910T3 (es) 2014-07-25 2019-10-10 Incumedx Inc Bobinas embólicas cubiertas
US9918718B2 (en) 2014-08-08 2018-03-20 DePuy Synthes Products, Inc. Embolic coil delivery system with retractable mechanical release mechanism
US9770577B2 (en) 2014-09-15 2017-09-26 Medtronic Xomed, Inc. Pressure relief for a catheter balloon device
TWI789782B (zh) 2014-09-17 2023-01-11 美商亞提歐醫藥公司 醫療系統
US9579484B2 (en) 2014-09-19 2017-02-28 Medtronic Vascular, Inc. Sterile molded dispenser
GB2533087B (en) 2014-12-08 2018-08-08 Cook Medical Technologies Llc Medical implant detachment mechanism and introducer assembly
US9692557B2 (en) 2015-02-04 2017-06-27 Stryker European Holdings I, Llc Apparatus and methods for administering treatment within a bodily duct of a patient
US10888331B2 (en) * 2015-02-10 2021-01-12 Boston Scientific Scimed, Inc. Active release of embolic coils
US11291798B2 (en) 2015-03-03 2022-04-05 Kaneka Medix Corporation Vascular embolization device and production method therefor
WO2016178171A1 (en) 2015-05-07 2016-11-10 The Medical Research Infrastructure And Health Services Fund Of The Tel-Aviv Medical Center Temporary interatrial shunts
US9717503B2 (en) 2015-05-11 2017-08-01 Covidien Lp Electrolytic detachment for implant delivery systems
US10398874B2 (en) 2015-05-29 2019-09-03 Covidien Lp Catheter distal tip configuration
US10154905B2 (en) 2015-08-07 2018-12-18 Medtronic Vascular, Inc. System and method for deflecting a delivery catheter
US10307168B2 (en) 2015-08-07 2019-06-04 Terumo Corporation Complex coil and manufacturing techniques
WO2017027740A1 (en) 2015-08-11 2017-02-16 Microvention, Inc. System and method for implant delivery
WO2017049314A1 (en) 2015-09-18 2017-03-23 Microvention, Inc. Pushable implant delivery system
US10335299B2 (en) 2015-09-18 2019-07-02 Terumo Corporation Vessel prosthesis
CN108260342B (zh) 2015-09-18 2021-07-30 微仙美国有限公司 可释放递送系统
US10617544B2 (en) 2015-09-18 2020-04-14 Microvention, Inc. Implant retention, detachment, and delivery system
US10292804B2 (en) 2015-09-21 2019-05-21 Stryker Corporation Embolectomy devices
US10441404B2 (en) 2015-09-21 2019-10-15 Stryker Corporation Embolectomy devices
US10172632B2 (en) 2015-09-22 2019-01-08 Medtronic Vascular, Inc. Occlusion bypassing apparatus with a re-entry needle and a stabilization tube
CN108024815B (zh) 2015-10-06 2020-11-27 波士顿科学国际有限公司 用于栓塞线圈的推动器臂和球释放机构
US20170100143A1 (en) 2015-10-07 2017-04-13 Stryker Corporation Multiple barrel clot removal devices
US10327791B2 (en) 2015-10-07 2019-06-25 Medtronic Vascular, Inc. Occlusion bypassing apparatus with a re-entry needle and a distal stabilization balloon
US10786302B2 (en) 2015-10-09 2020-09-29 Medtronic, Inc. Method for closure and ablation of atrial appendage
US20190021737A1 (en) 2015-10-14 2019-01-24 Three Rivers Medical Inc. Mechanical embolization delivery apparatus and methods
US10271873B2 (en) 2015-10-26 2019-04-30 Medtronic Vascular, Inc. Sheathless guide catheter assembly
US11090055B2 (en) 2015-10-30 2021-08-17 Incumedx Inc. Devices and methods for delivering an implant to a vascular disorder
US20170147765A1 (en) 2015-11-19 2017-05-25 Penumbra, Inc. Systems and methods for treatment of stroke
US10631946B2 (en) 2015-11-30 2020-04-28 Penumbra, Inc. System for endoscopic intracranial procedures
EP3386580B1 (en) 2015-12-09 2023-11-01 Medtronic Vascular Inc. Catheter with a lumen shaped as an identification symbol
US10159568B2 (en) 2015-12-14 2018-12-25 Medtronic, Inc. Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis
US10500046B2 (en) 2015-12-14 2019-12-10 Medtronic, Inc. Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis
US10743883B2 (en) 2015-12-30 2020-08-18 Stryker European Holdings I, Llc Embolic devices and methods of manufacturing same
US20170189033A1 (en) 2016-01-06 2017-07-06 Microvention, Inc. Occlusive Embolic Coil
US10070950B2 (en) 2016-02-09 2018-09-11 Medtronic Vascular, Inc. Endoluminal prosthetic assemblies, and associated systems and methods for percutaneous repair of a vascular tissue defect
EP3413963A4 (en) 2016-02-10 2019-09-18 Microvention, Inc. ACCESS TO AN INTRAVASCULAR TREATMENT SITE
US10729447B2 (en) 2016-02-10 2020-08-04 Microvention, Inc. Devices for vascular occlusion
US10188500B2 (en) 2016-02-12 2019-01-29 Medtronic Vascular, Inc. Stent graft with external scaffolding and method
US10485579B2 (en) 2016-02-25 2019-11-26 Indian Wells Medical, Inc. Steerable endoluminal punch
US20170258476A1 (en) 2016-03-08 2017-09-14 Terumo Kabushiki Kaisha Blood vessel treatment method
CN108601647B (zh) 2016-03-31 2020-10-02 美敦力瓦斯科尔勒公司 具有流体吸收性成分的修复脉管组织缺损用腔内假体装置
EP3436124B1 (en) 2016-03-31 2022-08-31 Medtronic Vascular Inc. Expandable introducer sheath having a steering mechanism
US10695542B2 (en) 2016-04-04 2020-06-30 Medtronic Vascular, Inc. Drug coated balloon
US10252024B2 (en) 2016-04-05 2019-04-09 Stryker Corporation Medical devices and methods of manufacturing same
US10441407B2 (en) 2016-04-12 2019-10-15 Medtronic Vascular, Inc. Gutter filling stent-graft and method
US9987122B2 (en) 2016-04-13 2018-06-05 Medtronic Vascular, Inc. Iliac branch device and method
US10010403B2 (en) 2016-04-18 2018-07-03 Medtronic Vascular, Inc. Stent-graft prosthesis and method of manufacture
US20170304097A1 (en) 2016-04-21 2017-10-26 Medtronic Vascular, Inc. Stent-graft delivery system having an inner shaft component with a loading pad or covering on a distal segment thereof for stent retention
US10940294B2 (en) 2016-04-25 2021-03-09 Medtronic Vascular, Inc. Balloon catheter including a drug delivery sheath
WO2017189535A2 (en) 2016-04-25 2017-11-02 Stryker Corporation Anti-jamming and macerating thrombectomy apparatuses and methods
US9962178B2 (en) 2016-04-25 2018-05-08 Stryker Corporation Pre-loaded inverting tractor thrombectomy apparatuses
US10517711B2 (en) 2016-04-25 2019-12-31 Medtronic Vascular, Inc. Dissection prosthesis system and method
WO2017189591A1 (en) 2016-04-25 2017-11-02 Stryker Corporation Inverting mechanical thrombectomy apparatuses and methods of use in the vasculature
US10191615B2 (en) 2016-04-28 2019-01-29 Medtronic Navigation, Inc. Method and apparatus for image-based navigation
US10406011B2 (en) 2016-04-28 2019-09-10 Medtronic Vascular, Inc. Implantable medical device delivery system
US11147952B2 (en) 2016-04-28 2021-10-19 Medtronic Vascular, Inc. Drug coated inflatable balloon having a thermal dependent release layer
FR3050635A1 (fr) 2016-05-02 2017-11-03 Univ Strasbourg Ballonnet gonflable et detachable, destine a etre implante dans une cavite corporelle, necessaire de traitement et procede de vidange associes
US10292844B2 (en) 2016-05-17 2019-05-21 Medtronic Vascular, Inc. Method for compressing a stented prosthesis
CN113648518B (zh) 2016-06-01 2023-10-20 微仙美国有限公司 改进加强的气囊导管
US10285710B2 (en) 2016-06-01 2019-05-14 DePuy Synthes Products, Inc. Endovascular detachment system with flexible distal end and heater activated detachment
US10517624B2 (en) 2016-06-03 2019-12-31 Stryker Corporation Inverting thrombectomy apparatuses and methods
US10646689B2 (en) 2016-07-29 2020-05-12 Cephea Valve Technologies, Inc. Mechanical interlock for catheters
JP7237313B2 (ja) 2016-07-29 2023-03-13 シャンハイ ワラビー メディカル テクノロジーズ カンパニー インコーポレイテッド インプラント送達システムおよび方法
WO2018053314A1 (en) 2016-09-16 2018-03-22 Greg Mirigian Occlusive implants with fiber-based release structures
US10258492B2 (en) * 2017-03-03 2019-04-16 Cook Medical Technologies Llc Prosthesis delivery system with axially collapsible sheath
US10806462B2 (en) 2017-12-21 2020-10-20 DePuy Synthes Products, Inc. Implantable medical device detachment system with split tube and cylindrical coupling
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
US10806461B2 (en) 2018-04-27 2020-10-20 DePuy Synthes Products, Inc. Implantable medical device detachment system with split tube
US10631791B2 (en) 2018-06-25 2020-04-28 Caption Health, Inc. Video clip selector for medical imaging and diagnosis
US11564692B2 (en) 2018-11-01 2023-01-31 Terumo Corporation Occlusion systems
US11147562B2 (en) 2018-12-12 2021-10-19 DePuy Synthes Products, Inc. Systems and methods for embolic implant detachment
US11207494B2 (en) 2019-07-03 2021-12-28 DePuy Synthes Products, Inc. Medical device delivery member with flexible stretch resistant distal portion

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060276829A1 (en) * 2005-06-02 2006-12-07 Keith Balgobin Stretch resistant embolic coil delivery system with mechanical release mechanism
US20080228215A1 (en) * 2007-03-13 2008-09-18 Micro Therapeutics, Inc. Implant including a coil and a stretch-resistant member
CN103099692A (zh) * 2011-09-27 2013-05-15 科德曼及舒特莱夫公司 用于血管装置的远端分离机构
US20140277093A1 (en) * 2013-03-14 2014-09-18 Stryker Nv Operations Limited Vaso-occlusive device delivery system
US20150182227A1 (en) * 2013-12-27 2015-07-02 Blockade Medical, LLC Coil system
US20180325706A1 (en) * 2015-01-20 2018-11-15 Neurogami Medical, Inc. Vascular implant

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114081568A (zh) * 2021-11-19 2022-02-25 心凯诺医疗科技(上海)有限公司 一种栓塞材料及其输送系统
CN114081568B (zh) * 2021-11-19 2022-08-30 心凯诺医疗科技(上海)有限公司 一种包含栓塞材料及其输送系统的组合件

Also Published As

Publication number Publication date
US11147562B2 (en) 2021-10-19
JP7412997B2 (ja) 2024-01-15
ES2901928T3 (es) 2022-03-24
EP3666202A1 (en) 2020-06-17
JP2020093099A (ja) 2020-06-18
US20200187951A1 (en) 2020-06-18
KR20200072433A (ko) 2020-06-22
EP3666202B1 (en) 2021-11-03
CN111297428B (zh) 2024-06-18

Similar Documents

Publication Publication Date Title
CN111297428B (zh) 用于栓塞植入物分离的系统和方法
US20210196281A1 (en) Systems and methods for embolic implant detachment
EP3753529B1 (en) Pull wire detachment for intravascular devices
EP3501427B1 (en) Implantable medical device detachment system with split tube and cylindrical coupling
US8795316B2 (en) Implantable medical device delivery system with a frangible portion and methods of making and using the same
US8425537B2 (en) Method of using interventional medical device system having an elongation retarding portion
CN104042299B (zh) 具有机械拆卸的闭塞装置递送系统
US10159489B2 (en) Systems and methods for delivering multiple embolization coils
EP4257062A2 (en) Delivery and detachment systems for vascular implants
EP3865079A1 (en) Intravascular implant deployment system
EP3302303A1 (en) Mechanical embolization delivery apparatus and methods
CN108348258B (zh) 用于将植入物输送到血管病症部位的装置和方法
EP4059446A1 (en) Systems and methods for embolic implant detachment
JP7508283B2 (ja) 血管内装置のためのプルワイヤの取り外し
US20230310005A1 (en) Systems and methods for embolic implant deployment
CN116421248A (zh) 具有扭绞环线的医疗装置递送系统
KR20230104529A (ko) 혈관내 클립 전개를 위한 시스템 및 방법
CN115137430A (zh) 具有柔性抗拉伸远侧部分的医疗装置递送构件

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant