CN111295449B - 腺病毒载体及其用途 - Google Patents

腺病毒载体及其用途 Download PDF

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CN111295449B
CN111295449B CN201880071243.0A CN201880071243A CN111295449B CN 111295449 B CN111295449 B CN 111295449B CN 201880071243 A CN201880071243 A CN 201880071243A CN 111295449 B CN111295449 B CN 111295449B
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adenovirus
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T·G·乌伊尔
S·罗伊
J·维林加
S·卡恩
J·H·H·V·屈斯泰
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Janssen Vaccines and Prevention BV
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Abstract

本文提供了嵌合腺病毒载体。所提供的嵌合腺病毒载体可用于在受试者中诱导保护性免疫应答。

Description

腺病毒载体及其用途
技术领域
本发明涉及生物技术。更具体地说,涉及腺病毒载体诸如复制缺陷型腺病毒载体在宿主中递送抗原并引发免疫应答的领域和用途。
背景技术
重组腺病毒载体广泛应用于基因治疗应用和疫苗。基于AdV-5载体的疫苗已显示出在多种动物模型中引发强有力的和保护性的免疫应答(参见例如WO2001/02607;WO2002/22080;Shiver等人,Nature[自然]415:331(2002);Letvin等人,Ann.Rev.Immunol.[免疫学年鉴]20:73(2002);Shiver和Emini,Ann.Rev.Med.[医学年鉴]55:355(2004))。然而,基于重组AdV-5载体的疫苗的效用将可能受到人群中AdV-5特异性中和抗体(NAb)的高血清阳性率的限制。在小鼠、恒河猴和人的研究中,抗AdV-5免疫的存在已经显示出基本上抑制了基于AdV-5的疫苗的免疫原性。
一种在先前已被最常见的人腺病毒(例如AdV-5)感染或治疗的个体中规避预先存在的免疫性的有前景的策略涉及开发来自腺病毒血清型的重组载体,这些腺病毒血清型未遇到这种预先存在的免疫性。一种这样的策略基于嵌合腺病毒的使用,这些嵌合腺病毒包括用来自具有低(或无)血清阳性率的腺病毒的衣壳蛋白序列(例如,六邻体蛋白序列和/或纤维蛋白序列)替换天然衣壳蛋白序列(例如,六邻体蛋白序列和/或纤维蛋白序列)。
因此,本领域需要可大量生产的、在宿主中不会遇到预先存在的免疫、但仍具有免疫原性并能够诱导针对由插入载体中的异源核酸编码的抗原的强烈免疫应答的替代性腺病毒载体。
发明内容
本文提供了腺病毒载体。该腺病毒载体可以包含编码六邻体多肽的核酸序列,该六邻体多肽包括含有选自SEQ ID NO:1或SEQ ID NO:2的氨基酸序列的含六邻体高变区多肽。在某些实施例中,该腺病毒载体可以包含含有SEQ ID NO:3或SEQ ID NO:4的六邻体多肽序列。
在某些实施例中,该腺病毒载体进一步包含E1缺失。在某些实施例中,该腺病毒载体进一步包含E3缺失。该腺病毒载体可以进一步包含人腺病毒-5(HAdV-5)E4 orf6。该腺病毒载体可以例如包含选自SEQ ID NO:5或SEQ ID NO:6的核酸序列。
在某些实施例中,该腺病毒载体进一步包含至少一个转基因。在某些实施例中,该至少一个转基因位于E1缺失处、E3缺失处、和/或右反向末端重复序列(rITR)附近。
在某些实施例中,该腺病毒载体包含来自人腺病毒-26(Ad26)的一种或多种核酸序列。
还提供了包含本文所述的腺病毒载体的重组细胞。还提供了产生这些腺病毒载体的方法。这些方法包括(a)使本文所述的重组细胞在用于生产该腺病毒载体的条件下生长;以及(b)从该重组细胞中分离该腺病毒载体。
还提供了包含本文所述的腺病毒载体和药学上可接受的载剂的免疫原性组合物。还提供了在有需要的受试者中诱导免疫应答的方法。这些方法包括向该受试者施用本文所述的免疫原性组合物。还提供了生产免疫原性组合物的方法,这些方法包括将本文所述的腺病毒载体与药学上可接受的载剂组合。
附图说明
当结合附图阅读时,将更好地理解前述发明内容以及本申请的优选实施例的以下详细描述。然而,应当理解,本申请不限于附图中所示的精确实施例。
图1显示了本文所述的六邻体嵌合载体的六邻体序列替换的示意图。图1A显示示意图,示出了五个六邻体基因区段(灰色条)和七个短高变区(HVR)(黑色条)在全长HAdV-26六邻体基因(空白条)中的位置,这些HVR之前在HAdV-5与HAdV-48六邻体之间交换以生成六邻体嵌合HAdV-5载体Ad5HVR48(1-7)(Roberts等人,Nature[自然]441:239-43(2006))。图1B显示HAdV-26、PtroAdV-1、PtroAdV-12和PtroAdV-13的六邻体多肽序列的部分比对。灰色条对应于在HAdV-26与PtroAdV-1、PtroAdV-12或PtroAdV-13之间交换的五个六邻体基因区段。黑色条表示与在HAdV-5与HAdV-48之间交换的上述先前指定的HVR对应的序列。
图2显示嵌合pAd26载体的示意图。图2A显示pAd26.HVRPtr12.luc(SEQ ID NO:21)的一般特征的示意图。图2B显示pAd26.HVRPtr13.luc(SEQ ID NO:22)的一般特征的示意图。
图3显示pAd26.ApoA1.RSVF-2A-GLuc(SEQ ID NO:29)的一般特征的示意图。
图4显示用于生成腺病毒载体Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc(在补充E1的细胞中)的同源重组策略的示意图。
图5显示由Ad26HVRPtr12.FLuc和Ad26HVRPtr13.FLuc诱导的细胞和体液免疫应答。图5A显示了实验设置。图5B显示由Ad26.FLuc、Ad26HVRPtr12.FLuc和Ad26HVRPtr13.FLuc诱导的针对载体编码的抗原(即Fluc,萤火虫萤光素酶)的免疫反应的图,如通过干扰素γ(IFN-γ)ELISPOT分析所测定的。y轴显示每106个脾细胞的点形成单位(SFU)的数量,虚线表示培养基刺激的95%百分位数。
图6显示由Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc诱导的细胞和体液免疫应答。图6A显示实验设置。图6B显示在用Ad26.RSVF-2A-GLuc、Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc免疫后八周时进行的RSV A2病毒中和试验(VNA)的结果。图6C显示由Ad26.RSVF-2A-GLuc、Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc诱导的针对载体编码的抗原RSV F的细胞免疫应答,如通过IFN-γELISPOT分析所测定的。y轴显示每106个脾细胞的点形成单位(SFU)的数量,虚线表示培养基刺激的95%百分位数。图6D显示由免疫后8周免疫小鼠血清中的Ad26.RSVF-2A-GLuc、Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc诱导的RSVF特异性IgG结合抗体的图。该图描绘以终点滴度(log10)计算的IgG ELISA滴度。
图7显示在用腺病毒载体Ad35、Ad26、Ad5、Ad4、Ad26HVRPtr12和Ad26HVRPtr13免疫的小鼠中诱导的同源和异源腺病毒中和滴度。
图8显示Ad26、Ad5、Ad26HVRPtr12和Ad26HVRPtr13在200个来自年龄为18-55岁、生活在美国(US)和欧盟(EU)的成人的人类群组血清样品中的血清阳性率。将这些血清中针对每种载体测得的中和滴度分成四个类别(<16(无中和)、16至300、300至1,000、1000至4000和>4000),如在所示的图表中表示的。
图9显示新型衣壳嵌合载体AdHVRPtr12.FLuc和Ad26HVRPtr13.FLuc在生产细胞系sPER.C6中的生产率。
具体实施方式
本披露至少部分地基于包含人骨架且包含嵌合六邻体多肽序列或纤维多肽序列中的至少一者的嵌合腺病毒载体的创建。腺病毒载体能够引起免疫应答,同时保持低血清阳性率。这些腺病毒载体可以被配制成疫苗并用于诱导针对感兴趣的特异性抗原的保护性免疫。
在背景技术和整个说明书中引用或描述了各种出版物、文章和专利;这些参考文献各自通过援引以其全文并入本文。包括在本说明书中的对文件、法案、材料、装置、制品等的讨论用于提供本发明的背景的目的。这种讨论不承认任何或所有这些事项形成关于所披露或要求保护的任何发明的现有技术的一部分。
除非另外定义,否则本文所用的所有科学和技术术语具有如本发明所属领域的普通技术人员通常理解的相同含义。否则,本文所用的某些术语具有说明书中阐述的含义。
必须注意,除非上下文另外明确规定,否则如本文和所附权利要求中所用,单数形式“一个/一种”和“该”包括复数指示物。
除非另有说明,否则任何数值,诸如本文所述的浓度或浓度范围,应被理解为在所有情况下都被术语“约”修饰。因此,数值典型地包括列举值±10%。例如,1mg/mL的浓度包括0.9mg/mL至1.1mg/mL。同样地,1%至10%(w/v)的浓度范围包括0.9%(w/v)至11%(w/v)。如本文所用,数值范围的使用明确地包括所有可能的子范围,该范围内的所有单个数值,包括值的这些范围内的整数和分数,除非上下文另有明确指示。
除非另外指明,否则在一系列要素前面的术语“至少”应被理解为指该系列中的每一个要素。本领域技术人员将认识到或能够仅使用常规实验便确定本文所述的本发明的具体实施例的许多等同方案。这些等同方案也旨在包括在本发明中。
如本文所用,术语“包括”、“包含”、“具有”、“含有”或它们的任何其他变化,将被理解为意味着包括所述整数或整数组,而不排除任何其他整数或整数组,并且旨在是非排他性的或开放性的。例如,包含元件的清单的组合物、混合物、工艺、方法、物品或设备不一定限制于仅那些元件,而可以包括不是此类组合物、混合物、工艺、方法、物品或设备明确列出的或固有的其他元件。此外,除非明确地说明是相反的,否则“或”是指包括在内的或,而不是指排他性的或。例如,以下项中的任一者满足条件A或B:A是真(或存在)并且B是假(或不存在),A是假(或不存在)并且B是真(或存在),以及A和B二者都是真(或存在)。
如本文所用,多个引用的要素之间的连接术语“和/或”应被理解为涵盖单独的和组合的选项两者。例如,当两种要素由和/或连接时,第一选项是指在不具有第二要素的情况下第一要素的应用。第二选项是指在不具有第一要素的情况下第二要素的应用。第三选项是指第一要素和第二要素一起的应用。这些选项中的任一个应被理解为属于该含义之内,并且因此满足如本文所用的术语“和/或”的要求。这些选项中的多于一个的同时应用也应被理解为属于该含义之内,并且因此满足术语“和/或”的要求。
如本文所用,贯穿说明书和权利要求书所用的术语“由……组成”指示包括任何列举的整数或整数组,但不能将另外的整数或整数组添加至指定的方法、结构或组合物。
如本文所用,贯穿说明书和权利要求书所用的术语“基本上由……组成”指示包括任何列举的整数或整数组,并且任选地包括不实质性改变所指定的方法、结构或组合物的基本或新颖特性的任何列举的整数或整数组。参见M.P.E.P.§2111.03。
如本文所用,“受试者”是指任何动物,优选哺乳动物,最优选人,其将或已经通过根据本发明实施例的方法接种。如本文所用的术语“哺乳动物”涵盖任何哺乳动物。哺乳动物的实例包括但不限于牛、马、羊、猪、猫、狗、小鼠、大鼠、兔、豚鼠、猴、人等,更优选地是人。
词语“右”、“左”、“下”和“上”表示所参考的附图中的方向。
应当理解的是,当提及优选的发明的组分的规格或特征时,在此使用的术语“约”、“大约”、“总体上”、“基本上”、以及类似术语,指示描述的规格/特征不具有严格的界限或参数,并且并不从其排除功能上相同或相似的微小变化,如本领域普通技术人员将理解的那样。在最低程度上,包括数值参数的此类引用将包括将不改变最低有效位数的变化,使用本领域接受的数学的和产业的原理(例如化整误差、测量误差或其他系统误差、制造公差等)。
在两个或更多个核酸或多肽序列(例如六邻体和纤维多肽以及编码它们的多核苷酸)的上下文中,术语“相同的”或“同一性”百分比是指当进行比较和比对以获得最大对应性时,两个或更多个序列或子序列是相同的或具有指定百分比的相同氨基酸残基或核苷酸,如使用以下序列比较算法之一或通过目视检查所测量的。
对于序列比较,典型地,一个序列作为参考序列,测试序列与其进行比较。当使用序列比较算法时,将测试序列和参考序列输入计算机;如果需要,指定子序列坐标;以及指定序列算法程序参数。然后,序列比较算法基于指定的程序参数计算测试序列相对于参考序列的序列同一性百分比。
用于比较的序列的最佳比对可以例如通过Smith&Waterman,Adv.Appl.Math.[应用数学进展]2:482(1981)的局部同源性算法、通过Needleman&Wunsch,J.Mol.Biol.[分子生物学杂志]48:443(1970)的同源性比对算法、通过Pearson&Lipman,Proc.Nat’l.Acad.Sci.USA[美国国家科学院院刊]85:2444(1988)的类似性搜索方法、通过这些算法的计算机化实现形式(GAP、BESTFIT、FASTA和TFASTA,威斯康星遗传学软件包(WisconsinGenetics Software Package),遗传学计算机课题组(Genetics Computer Group),威斯康星州麦迪逊科学大道575号(575Science Dr.,Madison,WI))、或通过目视检查(一般参见Current Protocols in Molecular Biology[分子生物学实验室指南],F.M.Ausubel等人编,Current Protocols[实验室指南],格林出版联合公司(Greene PublishingAssociates,Inc.)和约翰威利父子公司(John Wiley&Sons,Inc.)的合资公司,(1995年增刊)(Ausubel))来进行。
适于确定序列同一性百分比和序列相似性百分比的算法的实例是BLAST和BLAST2.0算法,这些算法描述于Altschul等人(1990)J.Mol.Biol.[分子生物学杂志]215:403-410和Altschul等人(1977)Nucleic Acids Res.[核酸研究]25:3389-3402。用于进行BLAST分析的软件可通过国家生物技术信息中心(National Center for BiotechnologyInformation)公开获得。该算法涉及首先通过鉴定查询序列中长度为W的短字来鉴定高得分序列对(HSP),当与数据库序列中相同长度的字进行比对时,这些序列对匹配或满足一些正值阈值得分T。T被称为邻近字分值阈值(Altschul等人,同上)。这些初始的邻近字命中将作为种子,以用于启动搜索以发现包含它们的更长的HSP。然后,只要累积比对得分可以增加,字命中就沿着每个序列在两个方向上延伸。
对于核苷酸序列,累积得分使用参数M(一对匹配残基的奖励得分;总是>0)和N(错配残基的罚分;总是<0)来计算。对于氨基酸序列,使用评分矩阵来计算累积得分。当存在以下情况时,停止字命中在每个方向上的扩展:累积比对得分从其最大获得值下降数量X;由于一个或多个负得分残基比对的累积,累积得分变为零或更低;或者到达任一序列的末端。BLAST算法参数W、T和X决定比对的灵敏度和速度。BLASTN程序(用于核苷酸序列)使用11的字长(W)、10的期望值(E)、M=5、N=-4以及两条链的比较作为默认值。对于氨基酸序列,BLASTP程序使用3的字长(W)、10的期望值(E)和BLOSUM62评分矩阵作为默认值(参见Henikoff&Henikoff,Proc.Natl.Acad.Sci.USA[美国国家科学院院刊]89:10915(1989))。
除了计算序列同一性百分比之外,BLAST算法还进行两个序列之间相似性的统计学分析(参见例如Karlin&Altschul,Proc.Nat’l.Acad.Sci.USA[美国国家科学院院刊]90:5873-5787(1993))。BLAST算法提供的相似性的一种量度是最小和概率(P(N)),其提供两个核苷酸或氨基酸序列之间偶然发生匹配的概率的指示。例如,如果在测试核酸与参考核酸的比较中最小和概率小于约0.1,更优选小于约0.01,最优选小于约0.001,则认为该核酸与参考序列相似。
两个核酸序列或多肽基本上相同的另一个指示是由第一个核酸编码的多肽与由第二个核酸编码的多肽具有免疫交叉反应性,如下所述。因此,例如,如果某多肽和第二多肽仅因保守取代而不同,则两种肽通常基本上相同。两个核酸序列基本上相同的另一个指示是两个分子在严格条件下彼此杂交,如下所述。
如本文所用,术语“保护性免疫”或“保护性免疫应答”是指该接种疫苗的受试者能够控制对其进行了疫苗接种的致病因子的感染。致病因子可以是例如抗原基因产物或抗原蛋白,或其片段。通常,已经出现了“保护性免疫应答”的受试者仅出现轻度至中度临床症状或根本没有症状。通常,对某种因子具有“保护性免疫应答”或“保护性免疫”的受试者不会由于所述因子的感染而死亡。
术语“佐剂”定义为一种或多种引起免疫系统刺激的物质。在此上下文中,使用佐剂来增强对本发明的腺病毒载体的免疫应答。
如本文所用,术语“抗原基因产物或其片段”或“抗原蛋白”可包括细菌、病毒、寄生虫、或真菌蛋白、或其片段。优选地,抗原性蛋白或抗原性基因产物能够在宿主中产生保护性免疫应答,例如诱导针对疾病或感染(例如细菌、病毒、寄生虫或真菌疾病或感染)的免疫应答,和/或在受试者中产生针对疾病或感染的免疫(即,接种疫苗),其保护受试者抵抗疾病或感染。
如本文所用,术语“嵌合”是指包含两种或更多种通常不关联在一起的基因、核酸、蛋白质、肽或多肽的基因、核酸、蛋白质、肽或多肽。“嵌合”基因、核酸或蛋白质可以是两种或更多种不相关序列(例如,编码两种或更多种不同蛋白质的两种或更多种不同核酸)之间的融合体。“嵌合”基因、核酸或蛋白质可以是两种或更多种相关序列之间的融合体(例如,核酸编码相同的蛋白质,然而,核酸来自不同的来源材料,即,一种核酸是人的,另一种核酸是猿猴的)。
腺病毒载体
暴露于某些腺病毒已经导致针对某些腺病毒血清型的免疫应答,这可以影响腺病毒载体的功效。因为人腺病毒感染在人类中是常见的,所以在人群中抗人腺病毒的中和抗体的流行率高。预计个体中存在这种中和抗体会降低基于人腺病毒骨架的基因转移载体的功效。一种避免功效降低的方法是替换腺病毒衣壳蛋白上的表位,这些表位是中和抗体的靶标。衣壳蛋白上的靶序列可以用来自其他腺病毒(例如,猿猴腺病毒)的蛋白序列替换,这些腺病毒具有低流行性,并因此而言,针对这些腺病毒的中和抗体在人群中很少。
“衣壳蛋白”是指腺病毒衣壳上的蛋白或其功能片段或衍生物,其参与确定特定腺病毒的血清型和/或向性。衣壳蛋白典型地包括纤维蛋白、五邻体蛋白和/或六邻体蛋白。在某些实施例中,衣壳蛋白是腺病毒的完整或全长衣壳蛋白。在其他实施例中,衣壳蛋白是腺病毒的全长衣壳蛋白的片段或衍生物。在某些实施例中,由本发明的腺病毒载体编码的六邻体、五邻体和纤维具有相同或不同的腺病毒背景。
“六邻体多肽”指腺病毒六邻体外壳蛋白、其功能片段和衍生物。
“纤维多肽”指腺病毒纤维蛋白、其功能片段和衍生物。
针对腺病毒的中和抗体的一个靶标是主要外壳蛋白,即六邻体蛋白。用来自人群中罕见的腺病毒的六邻体蛋白或六邻体蛋白内的可变序列,替换六邻体蛋白或六邻体蛋白内的定义血清型并与中和抗体结合的可变序列,可以允许构建对通常在人中发现的抗体的中和不太敏感的腺病毒载体。
六邻体高变区(HVR)是六邻体多肽的表示不同腺病毒血清型中最高的变异性的区域。通常,这些HVR被认为与六邻体蛋白三聚体的溶剂暴露表面相对应(在完整的病毒颗粒的情况下),并且相关地,预期它们是抗体介导的腺病毒中和的重要决定因素(Roberts等人,Nature[自然]441:239-43(2006))。因此,将给定的腺病毒载体的六邻体HVR用在人类中具有低(或无)血清阳性率的腺病毒的六邻体HVR替换是在人类目标群体中规避预先存在的抗载体体液免疫的一种可能手段。因此,已经有许多研究探索六邻体嵌合性的概念,主要涉及基于HAdV-5的载体内的六邻体序列替换(Roy等人,J Virol.[病毒学杂志]72:6875-9(1998);Gall等人,J Virol.[病毒学杂志]72:10260-4(1998);Youil等人,Hum.Gene Ther.[人类基因治疗]13:311-20(2002);Wu等人J Virol.[病毒学杂志]76:12775-82(2002);Roy等人,Virology.[病毒学]333:207-14(2005);Roberts等人,Nature[自然]441:239-43(2006);Bradley等人,J Virol.[病毒学杂志]86:1267-72(2012);Yu等人,BiochemBiophys Res Commun.[生物化学与生物物理研究通讯]421:170-6(2012);Bruder等人,PLoS One.[公共科学图书馆:综合]7(4):e33920(2012))。
针对腺病毒的中和抗体的第二个靶标是纤维蛋白。用来自非人类来源的稀有腺病毒的纤维序列替换纤维蛋白,更优选替换纤维蛋白内的可变序列,还可以允许构建对通常在人中发现的抗体的中和不太敏感的腺病毒载体。上述纤维替换与六邻体替换的组合可赋予对通常在人中发现的抗体的中和的额外抗性。
本披露提供了包含转基因和嵌合六邻体核酸序列的嵌合腺病毒载体。这些腺病毒载体可以例如包含编码六邻体多肽的核酸序列,该六邻体多肽包括含有选自SEQ ID NO:1或SEQ ID NO:2的氨基酸序列的含六邻体高变区多肽。在某些实施例中,六邻体多肽序列包含SEQ ID NO:3或SEQ ID NO:4。腺病毒载体可以例如包含来自人腺病毒-4、人腺病毒-5、人腺病毒-26或人腺病毒-35的一种或多种核酸序列。在某些实施例中,腺病毒载体包含选自SEQ ID NO:5或SEQ ID NO:6的核酸序列。
“腺病毒载体”指衍生自或包含腺病毒基因组的至少一部分的重组载体。
典型地,本发明的腺病毒载体包含在例如质粒、粘粒或杆状病毒载体上的完整重组腺病毒基因组。本发明的核酸分子可以呈RNA形式或呈通过克隆而获得或以合成方式而产生的DNA形式。DNA可以是双链的或单链的。
普通技术人员将认识到,衍生自多种血清型的元件可以组合在单个腺病毒载体中,例如人或猿猴腺病毒。因此,可以产生组合了来自不同血清型的期望性质的嵌合腺病毒载体。因此,在一些实施例中,本发明的嵌合腺病毒载体可以将不存在预先存在的嵌合六邻体和/或纤维多肽序列免疫性与现有腺病毒载诸如rAd4、rAd5、rAd26或rAd35的高水平抗原递送和呈递能力相结合。
用作疫苗的腺病毒载体的优点包括易于操纵、良好的大规模可制造性以及基于多年的研究、开发、制造和临床试验经验的优异安全记录,这些临床试验使用了许多已报道的腺病毒载体。被用作疫苗的腺病毒载体通常提供对转基因编码的蛋白或转基因编码的抗原基因产物的良好免疫应答,包括细胞免疫应答。根据本发明的腺病毒载体可以基于任何类型的腺病毒,并且在某些实施例中是人腺病毒,其可以属于任何组或血清型。在优选的实施例中,重组腺病毒基于来自A、B、C、D、E、F或G组的人腺病毒。在其他优选的实施例中,重组腺病毒基于人腺病毒血清型5、11、26、34、35、48、49或50。在其他实施例中,它是可以为任何血清型的猿猴腺病毒,诸如黑猩猩或大猩猩腺病毒。在某些实施例中,重组腺病毒基于黑猩猩腺病毒1、3、7、8、21、22、23、24、25、26、27.1、28.1、29、30、31.1、32、33、34、35.1、36、37.2、39、40.1、41.1、42.1、43、44、45、46、48、49、50、67型或SA7P。
在更优选的实施例中,第二组合物的黑猩猩腺病毒载体是ChAdV3。重组黑猩猩腺病毒血清型3(ChAd3或cAd3)是亚群C腺病毒,其性质类似于人腺病毒血清型5(Ad5)的性质。ChAd3在评估丙型肝炎病毒(HCV)候选疫苗的人类研究中已显示出是安全的和免疫原性的(Barnes E等人2012Science translational medicine[科学转化医学]4:115ra1)。据报道,基于ChAd3的疫苗能够诱导与人Ad5载体疫苗相当的免疫应答。参见例如Peruzzi D等人2009Vaccine[疫苗]27:1293-300和Quinn KM等人2013J Immunol[免疫学杂志]190:2720-35;WO 2005/071093;WO 2011/0130627等。
腺病毒载体、其构建方法及其繁殖方法是本领域所熟知的,并且描述于例如美国专利号5,559,099、5,837,511、5,846,782、5,851,806、5,994,106、5,994,128、5,965,541、5,981,225、6,040,174、6,020,191和6,113,913,以及Thomas Shenk,“Adenoviridae andtheir Replication”[腺病毒及其复制],M.S.Horwitz,“Adenoviruses”[腺病毒],分别第67和68章,见于Virology[病毒学],B.N.Fields等人编,第3版,纽约雷文出版社有限公司(Raven Press,Ltd.,New York)(1996),以及本文提及的其他参考文献。典型地,腺病毒载体的构建涉及使用标准分子生物学技术,诸如以下文献中所述的那些技术:Sambrook等人,Molecular Cloning,a Laboratory Manual[分子克隆,实验室手册],第2版,纽约冷泉港的冷泉港出版社(Cold Spring Harbor Press,Cold Spring Harbor,N.Y.)(1989);Watson等人,Recombinant DNA[重组DNA],第2版,Scientific American Books[科学美国人](1992);和Ausubel等人,Current Protocols in Molecular Biology[分子生物学实验室指南],纽约威利国际科学出版公司(Wiley Interscience Publishers,NY)(1995);以及本文提及的其他参考文献。
在某些实施例中,腺病毒载体包含E1缺失和/或E3缺失。E1或E3缺失可以例如包括基因的完全缺失或部分缺失,其使得E1或E3基因产物具有功能缺陷。因此,在某些实施例中,腺病毒是复制缺陷型的,例如因为它在基因组的E1区含有缺失。如技术人员已知的,在缺失来自腺病毒基因组的必需区域的情况下,由这些区域编码的功能必须优选的是由生产细胞反式提供,即,当E1、E2和/或E4区域的部分或全部从腺病毒中缺失时,这些区域必须存在于生产细胞中,例如整合到其基因组中,或呈所谓的辅助腺病毒或辅助质粒形式。这些腺病毒还可以具有在E3区域中的缺失,该缺失对于复制是非必要的,因此不必补充这种缺失。E1、E2、E3和E4区域中的一个或多个也可以通过其他方法失活,诸如通过将感兴趣的转基因(通常与启动子连接)插入待失活的区域。
可以使用的生产细胞(有时在本领域中以及在本文还称为‘包装细胞’或‘补充细胞’)可以是可在其中繁殖所希望的腺病毒的任何生产细胞。例如,在生产细胞中完成重组腺病毒载体的繁殖,这些生产细胞补充腺病毒中的缺陷。此类生产细胞优选地在其基因组中至少具有腺病毒E1序列,并因而能够补充在E1区域中具有缺失的重组腺病毒。可以使用任何补充E1的生产细胞,诸如由E1永生化的人类视网膜细胞,例如911或PER.C6细胞(参见美国专利5,994,128)、E1转化的羊水细胞(参见欧洲专利1230354)、E1转化的A549细胞(参见例如WO 98/39411、美国专利5,891,690)、GH329:HeLa(Gao等人,2000,Hum Gene Ther[人类基因治疗]11:213-19)、293等。在某些实施例中,生产细胞是例如HEK293细胞、或PER.C6细胞、或911细胞、或IT293SF细胞等。在(Kovesdi等人,2010,Viruses[病毒]2:1681-703)中对生产细胞中的腺病毒载体的生产进行了综述。
在某些实施例中,腺病毒载体是包含一个或多个人腺病毒核酸序列的嵌合腺病毒载体。人腺病毒核酸可以选自例如人腺病毒-4(Ad-4)、人腺病毒-5(Ad-5)、人腺病毒-26(Ad-26)或人腺病毒-35(Ad-35)。在某些实施例中,E1缺陷型腺病毒载体包含人Ad5的腺病毒的E4-orf6编码序列。这使得此类腺病毒可在表达Ad5的E1基因的熟知的补充细胞系中繁殖,诸如293细胞或PER.C6细胞(参见例如Fallaux等人,1998,Hum Gene Ther[人类基因治疗]9:1909-17;Havenga等人,2006,J Gen Virol[普通病毒学杂志]87:2135-43;WO 03/104467,它们通过援引以其全文并入本文)。
在某些实施例中,腺病毒载体包含转基因。“转基因”是指异源核酸,它是不天然存在于载体中的核酸,并且根据本发明,转基因可编码在受试者中引发免疫应答的抗原性基因产物或抗原性蛋白。转基因可以例如通过标准分子生物学技术引入载体中。例如,可将转基因克隆到腺病毒载体的缺失的E1或E3区域中,或E4区域与rITR之间的区域中。通常,转基因可操作地连接至表达控制序列。在优选的实施例中,转基因在转基因插入位点被插入。
如果需要,可以对根据本发明实施例的六邻体或纤维核酸序列和/或对转基因进行密码子优化,以确保在治疗的宿主(例如人)中的正确表达。密码子优化是广泛应用于本领域的技术。
转基因可以在腺病毒衍生的启动子(例如,主要晚期启动子)的控制下(即,可操作地连接),或者可以在异源启动子的控制下。合适的异源启动子的实例包括CMV启动子和RSV启动子。优选地,启动子位于表达盒内的感兴趣的异源基因的上游。
在优选的实施例中,腺病毒载体包含选自SEQ ID NO:5或SEQ ID NO:6的核酸序列。
免疫原性组合物
免疫原性组合物是用于本发明的包含免疫有效量的纯化的或部分纯化的人腺病毒载体的组合物。所述组合物可以根据本领域熟知的方法被配制成疫苗(也称为“免疫原性组合物”)。此类组合物可以包含佐剂以增强免疫应答。鉴于本披露,可以通过本领域技术人员熟知的技术确定制剂中每种组分的最佳比率。
鉴于本披露,根据本发明的实施例的免疫原性组合物可以使用本领域技术人员已知的方法制备。液体药物组合物通常包含液体载剂,诸如水、石油、动物或植物油、矿物油或合成油。可以包括生理盐水溶液、葡萄糖或其他糖溶液或二醇,诸如乙二醇、丙二醇或聚乙二醇。
可用于本发明的免疫原性组合物可以包含佐剂。适于根据本发明共同施用的佐剂应该是在人中潜在安全、耐受良好且有效的佐剂,包括QS-21、Detox-PC、MPL-SE、MoGM-CSF、TiterMax-G、CRL-1005、GERBU、TERamide、PSC97B、Adjumer、PG-026、GSK-I、AS01、AS03、AS04、AS15、GcMAF、B-alethine、MPC-026、Adjuvax、CpG ODN、Betafectin、Alum和MF59。
其他可以施用的佐剂包括凝集素、生长因子、细胞因子和淋巴因子,诸如α-干扰素、γ-干扰素、血小板衍生生长因子(PDGF)、粒细胞集落刺激因子(gCSF)、粒细胞巨噬细胞集落刺激因子(gMCSF)、肿瘤坏死因子(TNF)、表皮生长因子(EGF)、IL-I、IL-2、IL-4、IL-6、IL-8、IL-10和IL-12或其编码核酸。
本发明的组合物可以包含药学上可接受的赋形剂、载剂、缓冲剂、稳定剂或本领域技术人员熟知的其他材料。此类材料应该是无毒的,并且不应该干扰活性成分的功效。载剂或其他材料的确切性质可以取决于施用途径,例如肌内、皮下、经口、静脉内、皮肤、粘膜内(例如,肠)、鼻内或腹膜内途径。
诱导保护性免疫的方法
本发明的另一个一般方面涉及在需要的受试者中诱导免疫应答的方法。这些方法可以例如包括向受试者施用包含本文所述的腺病毒载体和药学上可接受的载剂的疫苗。本文还提供了生产疫苗的方法。这些方法包括将本文所述的腺病毒载体与药学上可接受的载剂组合。
根据本发明的实施例的任何免疫原性组合物(包括但不限于本文所述的那些)均可在本发明方法中用作疫苗。
包含载体的免疫原性组合物/疫苗的施用典型地是肌内或皮下。然而,也可以设想其他施用方式,诸如静脉内、皮肤、皮内或鼻。免疫原性组合物的肌内施用可以通过使用针注射腺病毒载体的混悬液来实现。一种替代方案是使用无针注射装置来施用组合物(使用例如BiojectorTM)或含有疫苗的冷冻干燥粉末。
对于静脉内、皮肤或皮下注射,或在病痛部位的注射,载体将呈肠胃外可接受的水溶液的形式,它是无热原的并具有合适的pH、等渗性和稳定性。本领域技术人员完全能够使用例如等渗媒介物诸如氯化钠注射液、林格氏注射液、乳酸盐林格氏注射液来制备适合的溶液。根据需要,可以包括防腐剂、稳定剂、缓冲剂、抗氧化剂和/或其他添加剂。还可以使用缓释制剂。
典型地,施用将具有预防性目的,以在感染或发展症状之前产生针对感兴趣的抗原(例如,细菌、病毒、寄生虫和/或真菌病原体)的免疫应答。可根据本发明治疗或预防的疾病和病症包括免疫应答可在其中起到保护或治疗作用的那些。在其他实施例中,腺病毒载体可被施用用于暴露后预防。
将含有嵌合人腺病毒载体的免疫原性组合物施用给受试者,从而在受试者中产生对感兴趣的抗原的免疫应答。足以诱导可检测的免疫应答的组合物的量被定义为组合物的“免疫有效剂量”或“有效量”。本发明的免疫原性组合物可以诱导体液以及细胞介导的免疫应答。在典型的实施例中,免疫应答是保护性免疫应答。
施用的实际量以及施用的速率和时程将取决于正治疗的疾病的性质和严重度。治疗处方(例如剂量等的决定)是在全科医生和其他医师、或在兽医环境中是兽医的职责范围内的,并且典型地考虑了待治疗的病症、个体患者的状况、递送部位、施用方法以及医师已知的其他因素。以上提及的这些技术和方案的实例可以在Remington's PharmaceuticalSciences[雷明顿药学大全],第16版,Osol,A.编,1980中找到。
在产生腺病毒载体和任选将此类颗粒配制成组合物后,可以将这些载体施用给个体,特别是人或其他灵长类动物。可以对人或另一种哺乳动物施用,例如小鼠、大鼠、仓鼠、豚鼠、兔、绵羊、山羊、猪、马、牛、驴、猴、狗或猫。向非人哺乳动物的递送不必是为了治疗目的,而是可以用于实验环境,例如研究对腺病毒载体的免疫应答机制。
在一个示例性方案中,腺病毒载体以约100μl至约10ml范围内的体积施用(例如肌内),该体积的浓度为约104至1012个病毒颗粒/ml。优选地,腺病毒载体以0.1-2.0ml范围内的体积施用。例如,腺病毒载体可以100μl、500μl、1ml、2ml施用。更优选地,腺病毒载体以0.5ml的体积施用。任选地,腺病毒载体以107vp/ml、108vp/ml、109vp/ml、1010vp/ml、5x1010vp/ml、1011vp/ml或1012vp/ml的浓度施用。典型地,在一次施用期间,腺病毒载体以约109至约1012个病毒颗粒(vp)的量,更典型地以约1010至约1012个vp的量施用于人受试者。初始疫苗接种后如上所述进行加强免疫。
初始疫苗接种之后可以是从包含编码感兴趣抗原的相同腺病毒载体的疫苗/组合物或包含编码相同感兴趣抗原的不同腺病毒载体的疫苗/组合物的加强或激发。
如果需要,组合物可以存在于试剂盒、包装或分配器中,该试剂盒、包装或分配器可以包含一个或多个含有活性成分的单位剂型。例如,试剂盒可以包括金属或塑料箔,诸如泡罩包装。试剂盒、包装或分配器可附有施用说明书。
本发明的组合物可以单独施用或与其他治疗联合施用(同时地或按顺序),这取决于待治疗的病状。
实施例
实施例1是一种腺病毒载体,该腺病毒载体包含编码六邻体多肽的核酸序列,该六邻体多肽包括含有选自SEQ ID NO:1或SEQ ID NO:2的氨基酸序列的含六邻体高变区多肽。
实施例2是如实施例1所述的腺病毒载体,其中该六邻体多肽序列包含SEQ ID NO:3或SEQ ID NO:4。
实施例3是如实施例1或2所述的腺病毒载体,其中该腺病毒载体进一步包含E1缺失。
实施例4是如实施例1-3中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含E3缺失。
实施例5是如实施例1-4中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含人腺病毒-5(HAdV-5)E4 orf6。
实施例6是如实施例1-5中任一项所述的腺病毒载体,其中该腺病毒载体包含选自SEQ ID NO:5或SEQ ID NO:6的核酸序列。
实施例7是如实施例1-6中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含至少一个转基因。
实施例8是如实施例1-7中任一项所述的腺病毒载体,其中该转基因位于E1缺失处、E3缺失处、和/或右反向末端重复序列(rITR)附近。
实施例9是如实施例1-8中任一项所述的腺病毒载体,其中该腺病毒载体包含来自人腺病毒-26(Ad26)的一种或多种核酸序列。
实施例10是一种重组细胞,该重组细胞包含如实施例1-9中任一项所述的腺病毒载体。
实施例11是一种生产腺病毒载体的方法,该方法包括:(a)使如实施例10所述的重组细胞在用于生产该腺病毒载体的条件下生长;以及(b)从该重组细胞中分离该腺病毒载体。
实施例12是一种免疫原性组合物,该免疫原性组合物包含如实施例1-9中任一项所述的腺病毒载体和药学上可接受的载剂。
实施例13是一种在有需要的受试者中诱导免疫应答的方法,该方法包括向该受试者施用如实施例12所述的免疫原性组合物。
实施例14是一种生产免疫原性组合物的方法,该方法包括将如实施例1-9中任一项所述的腺病毒载体与药学上可接受的载剂组合。
实例
实例1:六邻体嵌合腺病毒载体Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13的设计。
在此实例中描述的是Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13的设计,它们是携带从黑猩猩腺病毒获得的某些六邻体序列替换的新的基于HAdV-26的载体。设计这些六邻体嵌合腺病毒载体的目的是生成可能的新的基于腺病毒的(疫苗)载体,这些载体是可制造的,在血清学上与HAdV-26不同,并且在人类人群中针对这些载体存在低(或无)预先存在的免疫。
将分别包含腺病毒载体基因组序列SEQ ID NO:4、SEQ ID NO:5和SEQ ID NO:6的Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13设计为先前描述(WO2007104792 A2;Abbink等人,2007)的重组HAdV-26载体的六邻体嵌合形式。因此,这些载体被设计成携带与先前指定的(WO 2007104792 A2;Abbink等人,2007)相同的E1缺失、E3缺失和E4 orf6替换(被HAdV-5中的替换)。
如以下实例所述,本文生成和检查的六邻体嵌合载体的特定变体是Ad26HVRPtr1.Fluc、Ad26HVRPtr12.Fluc、Ad26HVRPtr13.Fluc、Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc,它们分别包含病毒基因组序列SEQ ID NO:7、SEQ IDNO:8、SEQ ID NO:9、SEQ ID NO:10和SEQ ID NO:11。如其载体名称所示,生成这些载体以在其E1缺失的位置处携带CMV启动子驱动的表达盒,该表达盒编码萤火虫萤光素酶(FLuc)或嵌合蛋白“RSV-FA2-2A-GLuc”(RSVF-2A-GLuc),后者是呼吸道合胞病毒株A2融合糖蛋白(RSV-F2A)、口蹄疫病毒2A肽和高斯(Gaussia)萤光素酶(GLuc)的融合体。FLuc表达盒和RSVF-2A-GLuc表达盒均由CMV启动子驱动,并携带SV40聚腺苷酸化信号。RSVF-2A-GLuc的盒进一步在其5’未翻译区内包含一个序列,该序列包含人载脂蛋白A1(ApoA1)基因的内含子2。
腺病毒载体Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13(分别包含SEQ ID NO:4、SEQ ID NO:5和SEQ ID NO:6)在其基于HAdV-26的基因组内的某些六邻体基因区段被其他腺病毒的相应六邻体基因区段替换的意义上被设计为六邻体嵌合的。充当Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13的六邻体序列供体的病毒分别是PtroAdV-1、PtroAdV-12和PtroAdV-13。这些病毒是在野生黑猩猩的粪便样品中鉴定出来的,并且已分配给人类腺病毒E种(HAdV-E)(Wevers等人,J.Virol.[病毒学杂志]85(20):10774-84(2011))。这些病毒的部分六邻体基因序列分别以GenBank登录号JN163971、JN163982和JN163983公开提供。考虑到六邻体序列的受体载体基于HAdV-26,即人腺病毒D种(HAdV-D)的成员,而三种六邻体序列供体病毒属于HAdV-E,本文产生的载体代表交叉腺病毒种六邻体嵌合载体。
HAdV-26六邻体基因区段(在本文被替换以生成六邻体嵌合载体Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13(及其在本文构建的含有转基因表达盒的衍生物))对应于以Genbank登录号EF153474(版本1)保藏的HAdV-26的野生型完整基因组的核苷酸18178至18357、18379至18438、18556至18633、18685至18723和19027至19158。这五个HAdV-26六邻体基因区段以及它们相应的衍生自PtroAdV-1、PtroAdV-12或PtroAdV-13的替换区段在很大程度上但并非完全对应于编码高变区(HVR)的序列。这显示在图1A中,其中在HAdV-26六邻体基因的示意图中指出了这五个区段的位置以及之前指定的HVR的位置。此外,这更详细地通过用HAdV-26、PtroAdV-1、PtroAdV-12和PtroAdV-13的(部分)六邻体多肽序列进行的氨基酸比对来说明,其中在本文进行交换的特定区段在先前指定的HVR的旁边特别突出显示(图1B)。
值得注意的是,HAdV-26的五个六邻体基因区段(在本文被替换以生成Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13)并不完全对应于在描述六邻体嵌合的基于HAdV-5的载体的先前报告中被替换的含六邻体HVR的序列(Roberts等人,Nature[自然]441:239-43(2006);Bradley等人,J Virol.[病毒学杂志]86:1267-72(2012);Yu等人,Biochem Biophys Res Commun.[生物化学与生物物理研究通讯]421:170-6(2012);Bruder等人,PLoS One.[公共科学图书馆:综合]7(4):e33920(2012))。例如,如图1A和图1B所示,五个六邻体基因区段未能完全对应于七个氨基酸段(先前被交换以生成Ad5HVR48(1-7)),Ad5HVR48(1-7)是基于HAdV-5并包含HAdV-48的六邻体HVR的六邻体嵌合载体(Roberts等人,Nature[自然]441:239-43(2006))。
腺病毒载体Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13的完整嵌合六邻体基因核苷酸序列分别在SEQ ID NO:13、SEQ ID NO:14和SEQ ID NO:15中列出。这些载体的完整嵌合六邻体多肽序列分别在SEQ ID NO:12、SEQ ID NO:3和SEQ ID NO:4中列出。
实例2:携带Ad26HVRPtr1.Fluc、Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc的完整腺病毒载体基因组的质粒的分子构建
使用与先前针对生成六邻体嵌合的编码Fluc的载体“Ad26.HVR5C”所述的相同方法和策略(Ma等人,J.Canc.Res.Clin.Oncol.[癌症研究与临床肿瘤学杂志]141(3):419-29(2015),补充图4),构建含有Ad26HVRPtr1、Ad26HVRPtr12和Ad26HVRPtr13载体基因组的质粒,这些质粒在腺病毒E1区域中携带CMV启动子驱动的FLuc表达盒。简而言之,首先在中间“六邻体穿梭”质粒pHex26-Shuttle.BamHI的背景下引入对六邻体基因的所需改变。这通过标准基因合成和亚克隆程序(由利福尼亚州卡尔斯巴德的生命科技公司(LifeTechnologies,Carlsbad,CA)的GeneArt进行)完成,并产生了修饰的六邻体穿梭质粒,这些质粒携带SEQ ID NO:13、SEQ ID NO:14和SEQ ID NO:15所示的上述嵌合六邻体基因序列。然后,通过在大肠杆菌(E.coli)BJ5183(Stratagene/加利福尼亚州圣克拉拉的安捷伦科技公司(Agilent Technologies,Santa Clara,CA))中进行同源重组,将嵌合六邻体基因从六邻体穿梭质粒穿梭到pAd26.luc.dH中,pAd26.luc.dH是一种在两个PacI限制性位点之间携带六邻体基因缺失型重组HAdV-26载体基因组的质粒,该载体基因组在其E1缺失位置处装有CMV启动子驱动的编码Fluc的表达盒。上述分子克隆程序导致生成了质粒pAd26.HVRPtr1.luc(SEQ ID NO:20)、pAd26.HVRPtr12.luc(SEQ ID NO:21;图2A)和pAd26.HVRPtr13.luc(SEQ ID NO:22;图2B)。
还以与如上所述完全相同的方式构建了三个匹配的对比六邻体嵌合腺病毒载体质粒。在这些名为pAd26.HVR5.luc(SEQ ID NO:17)、pAd26.HVR35.luc(SEQ ID NO:18)和pAd26.HVR52.luc(SEQ ID NO:19)的质粒中,分别用相应的HAdV-5、HAdV-35和HAdV-52区段组替换上述五种HAdV-26六邻体基因区段组。这些质粒分别包含SEQ ID NO:23、SEQ ID NO:24和SEQ ID NO:25所示的嵌合六邻体基因核苷酸序列。这些六邻体基因分别编码SEQ IDNO:26、SEQID NO:27和SEQ ID NO:28所示的嵌合六邻体多肽序列。
实例3:初步评估腺病毒载体Ad26HVRPtr1.Fluc、Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc的活力、生长效率和生产率
先前的研究已表明,包含腺病毒物种之间的六邻体序列交换的嵌合腺病毒载体通常是不能存活的,或可能显示出延迟的生长动力学并产生较低的产量(Youil等人,Hum.Gene Ther.[人类基因治疗]13:311-20(2002);Wu等人J Virol.[病毒学杂志]76:12775-82(2002);Bradley等人,J Virol.[病毒学杂志]86:1267-72(2012);Bruder等人,PLoS One.[公共科学图书馆:综合]7(4):e33920(2012))。因此,应测试新的六邻体嵌合腺病毒(疫苗)载体的基本生长特性、产量和颗粒质量。
评估本文设计和构建的六邻体嵌合腺病毒载体的活力、生长效率、生产率和颗粒感染性,将它们与其基于亲本HAdV-26的载体进行比较。为此,通过根据标准程序,使用Lipofectamine转染试剂(加利福利亚州卡尔斯巴德的英杰公司),将实例2中描述的相应腺病毒载体基因组质粒(即,分别为pAd26.HVRPtr1.luc、pAd26.HVRPtr12.luc、pAd26.HVRPtr13.luc、pAd26.HVR5,pAd26.HVR35和pAd26.HVR52)转染到在T25烧瓶中培养的补充E1的PER.55K细胞(Vogels等人,J Virol.[病毒学杂志]77:8263-71(2003))中,生成了腺病毒载体Ad26HVRPtr1.Fluc、Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc以及对比载体Ad26HVR5.Fluc、Ad26HVR35.Fluc和Ad26HVR52.Fluc。在转染之前,将腺病毒载体基因组质粒用PacI消化,以从质粒中释放相应的腺病毒载体基因组。每天监测转染的细胞培养物,以记录第一个病毒斑形成的开始天数以及达到总细胞病变效应(CPE)的天数(表1)。在完全CPE时,收集感染的细胞和培养基,并通过三个冻融循环释放病毒。在收获病毒拯救转染后,通过在补充E1的细胞培养物上的连续几轮感染而进一步扩增病毒。然后从粗病毒收获物中纯化病毒(通过两步氯化铯(CsCl)密度梯度超速离心程序),随后测定病毒颗粒(VP)和感染单位滴度(IU/mL),所有这些均通过前述标准方法进行(Alba R,Baker AH,NicklinSA.Vector systems for prenatal gene therapy:principles of adenovirus designand production.[用于产前基因治疗的载体系统:腺病毒设计和生产原理]Methods MolBiol[分子生物学方法]2012;891:55-84.:55-84)。
表1:六邻体嵌合腺病毒载体所观察到的拯救效率、最终产量和VP/IU比。
n.a.,不适用;p.t.,转染后
在所测试的六个嵌合载体中,只有Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc给出的结果表明它们的衣壳修饰不会损害载体生产率和感染性(表1)。这两个载体的病毒拯救和生长效率,如斑形成的开始时间和达到完全CPE所需的时间(病毒DNA转染到补充E1的细胞中后)所反映的,均在亲本载体Ad26.Fluc所见的范围内。除Ad26HVRPtr1.Fluc外,其他测试的嵌合载体并非如此。此外,在所有测试的载体中,Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc在大规模生产和纯化时产生最高的病毒颗粒(VP)产量。最后,虽然其他嵌合载体都显示出高于亲本Ad26.Fluc的VP:IU比率,但是发现Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc具有不受影响的VP:IU比率。
其他四个嵌合载体即Ad26HVR5.Fluc、Ad26HVR35.Fluc、Ad26HVR52.Fluc和Ad26HVRPtr1.Fluc显示出不同程度的受损的生产率和/或感染性。Ad26HVR52.Fluc根本不能存活(即,在病毒DNA转染后无法检测到病毒斑),而其他三个载体均成功获救。在这三个中,Ad26HVR5.Fluc和Ad26HVR35.Fluc清楚地显示出延迟的拯救和生长动力学,而Ad26HVRPtr1.Fluc似乎像亲本载体一样有效地拯救和生长。纯化的载体批次的表征揭示,Ad26HVR5.Fluc和Ad26HVRPtr1.Fluc的实际病毒颗粒产量尤其受到影响,而对所有这三个载体而言,颗粒感染性似乎都受到很大损害(如这些载体所见的较高VP:IU比率所示)。
总之,作为包含腺病毒物种之间的六邻体序列交换的六邻体嵌合载体的Ad26HVRPtr12和Ad26HVRPtr13显示出良好的生长和生产特性,并因此被认为是用作新的疫苗载体的有希望的候选物(从可制造性的角度来看)。通过使用相同的嵌合六邻体设计但使用其他腺病毒作为六邻体序列供体而生成的其他四个六邻体嵌合载体显示出不太有利的特性。
实例4:腺病毒载体Ad26HVRPtr12.Fluc和Ad26HVRPtr13.Fluc的生成
该实例描述在实例6、8和9中描述的免疫原性、血清阳性率、交叉中和和可制造性实验中使用的六邻体嵌合的编码Fluc的腺病毒载体的生成。
通过将相应的腺病毒载体基因组质粒(即,分别为pAd26.HVRPtr12.luc和pAd26.HVRPtr13.luc)转染到补充E1的PER.C6细胞中,生成了分别包含腺病毒载体基因组序列SEQ ID NO:8和SEQ ID NO:9的腺病毒载体Ad26HVRPtr12.Fluc(也称为Ad26C4NVT005)和Ad26HVRPtr13.Fluc(也称为Ad26C3NVT005)。在转染到PER.C6细胞(这些细胞在补充了10%胎牛血清(FBS)和10mM MgCl2的达尔伯克氏改良伊格尔培养基(DMEM)中作为贴壁细胞培养物生长)中之前,用PacI消化腺病毒载体基因组质粒以从质粒释放相应的腺病毒载体基因组。使用Lipofectamine转染试剂(加利福利亚州卡尔斯巴德的英杰公司(Invitrogen;Carlsbad,CA)),根据标准程序进行转染。在收获病毒拯救转染后,通过在PER.C6细胞培养物上的连续几轮感染而进一步扩增病毒。如前所述(Havenga等人,“Novel replication-incompetent adenoviral B-group vectors:high vector stability and yield inPER.C6 cells,”[新的无复制能力的腺病毒B组载体:在PER.C6细胞中的高载体稳定性和产率]J.Gen.Virol.[普通病毒学杂志]87(8):2135-43(2006)),使用两步氯化铯(CsCl)密度梯度超速离心程序从粗病毒收获物中纯化病毒。病毒颗粒(VP)滴度通过先前描述的基于分光光度法的程序进行测量(Maizel等人,“The polypeptides of adenovirus:I.Evidencefor multiple protein components in the virion and a comparison of types 2,7A,and 12,”[腺病毒的多肽:I.病毒体中多种蛋白组分的证据以及2、7A和12型的比较]Virology[病毒学],36(1):115-25(1968))。
实例5:腺病毒载体Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc的生成
该实例描述在实例7中描述的免疫原性实验中使用的六邻体嵌合的编码RSVF-2A-GLuc的腺病毒载体的生成。
分别包含腺病毒载体基因组序列SEQ ID NO:10和SEQ ID NO:11的腺病毒载体Ad26HVRPtr12.RSVF-2A-GLuc(也称为Ad26C4NVT001)和Ad26HVRPtr13.RSVF-2A-Gluc(也称为Ad26C3NVT001)的生成涉及分别使用前述质粒pAd26.HVRPtr12.luc(SEQ ID NO:21;图2A)和pAd26.HVRPtr13.luc(SEQ ID NO:22;图2b)以及质粒pAdApt26.ApoAI.RSVF-2A-GLuc(SEQ ID NO:29;图3)。
pAdApt26.ApoAI.RSVF-2A-GLuc是带有先前描述(WO 2007104792A2;Abbink等人,2007)的E1缺失型基于HAdV-26的载体的左端基因组片段的质粒,其在腺病毒E1缺失位置处进一步包含上述编码“RSV-FA2-2A-GLuc”的转基因表达盒(RSVF-2A-GLuc)。通过若干标准基因合成和分子克隆步骤构建了pAdApt26.ApoAI.RSVF-2A-GLuc,这些步骤一起产生所述RSVF-2A-GLuc盒并将其插入pAdApt26(先前描述(WO 2007104792A2;Abbink等人,2007)的带有所述左端腺病毒载体基因组片段的质粒)。
如下生成腺病毒载体Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc。通过限制酶PacI和PsiI消化质粒pAd26.HVRPtr12.luc和pAd26.HVRPtr13.luc,以便从这些质粒中释放一定的28kb,即包含嵌合六邻体序列的左端缺失型腺病毒载体基因组片段。将所得的相应消化产物各自分别用经PacI消化的pAdApt26.ApoAI.RSVF-2A-GLuc共转染到补充E1的PER.C6中,以便通过重叠的载体基因组限制片段之间的同源重组来拯救相应的六邻体嵌合的编码RSVF-2A-Gluc的病毒,如图4所示。在这种策略中,同源重组发生在pAdApt26.ApoAI.RSVF-2A-GLuc的6.7-kb PacI-PacI限制性片段(图4,顶部)与pAd26.HVRPtr12.luc或pAd26.HVRPtr13.luc的28-kb PsiI-PacI限制性片段(图4,底部)之间的重叠区域中的2.7-kb区域处。使用Lipofectamine转染试剂(加利福利亚州卡尔斯巴德的英杰公司(Invitrogen;Carlsbad,CA)),根据标准程序进行转染。将两种拯救的病毒Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-Gluc的单个分离斑进一步在PER.C6细胞上繁殖,然后按照本文实例4中针对载体Ad26HVRPtr12.FLuc和Ad26HVRPtr13.Fluc所述进行纯化和滴定。
由新型腺病毒载体诱导的细胞和体液免疫应答
实例6和7描述了为了评估本文生成的新型Ad26HVRPtr12和Ad26HVRPtr13载体的免疫原性而进行的实验。在这些实验中,评估了新型载体在小鼠中肌内免疫后诱导针对载体编码的(模型)抗原的体液和细胞免疫应答的能力。使用两种不同的抗原测试了载体:萤火虫萤光素酶(FLuc)和RSV-FA2-2A-GLuc(RSVF-2A-GLuc)。RSVF-2A-GLuc是一种嵌合蛋白,由呼吸道合胞病毒株A2融合糖蛋白、口蹄疫病毒2A肽和高斯萤光素酶(GLuc)组成。将每个载体与基于携带相同的编码抗原的转基因盒的人26型腺病毒(HAdV-26,在本文中也称为Ad26)的基准载体并排比较。使用众所周知的免疫测定法,诸如酶联免疫斑点测定法(ELISPOT)、酶联免疫吸附测定法(ELISA)以及在RSVF-2A-GLuc抗原的情况下,呼吸道合胞病毒中和测定法(VNA),测量了针对相应抗原的免疫应答。
实例6:由Ad26HVRPtr12.FLuc和Ad26HVRPtr13.FLuc诱导的细胞免疫应答
为了评估新型腺病毒载体Ad26HVRPtr12和Ad26HVRPtr13的细胞免疫原性,用表达FLuc的Ad26.FLuc(阳性对照)、Ad26HVRPtr12和Ad26HVRPtr13载体(即,Ad26HVRPtr12.FLuc和Ad26HVRPtr13.FLuc)或用不编码FLuc的腺病毒载体Ad26空对Balb/C小鼠进行肌内免疫。以每只小鼠109和1010个病毒颗粒(vp)测试表达FLuc的载体,并以1010vp施用Ad26空载体。免疫后两周,处死小鼠并分离脾细胞(图5A)。通过离体ELISPOT试验测定了细胞免疫应答,该试验测量用15mer重叠FLuc肽库过夜刺激脾细胞后IFN-γ分泌细胞的相对数量(图5B)。结果表明,在较高剂量免疫(1010)下,由Ad26HVRPtr12和Ad26HVRPtr13载体诱导的细胞免疫应答与Ad26.Fluc所见的在同一范围内或更高。
总的来说,由本发明的表达FLuc的重组Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体诱导的细胞免疫应答清楚地表明了这些载体在小鼠中的强有力的免疫原性。
实例7:由Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc诱导的细胞和体液免疫应答
使用RSV-FA2-2A-GLuc(RSVF-2A-GLuc)作为载体编码的(模型)疫苗抗原,进一步评估了新型Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体的免疫原性。用Ad26.RSVF-2A-GLuc(阳性对照)、Ad26HVRPtr12.RSVF-2A-GLuc或Ad26HVRPtr13.RSVF-2A-GLuc以三种不同的浓度(各自以每只小鼠108vp、109vp或1010vp)或者用Ad26.FLuc、Ad26HVRPtr12.FLuc或Ad26HVRPtr13.FLuc以每只小鼠1010vp对Balb/C小鼠进行肌内免疫。免疫后八周,处死小鼠并收集血样和脾细胞(图6A)。如下所述评估不同的免疫参数。
为了评估Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc引发呼吸道合胞病毒中和抗体的能力,进行了病毒中和试验(VNA)。图6B描绘了免疫后八周时收集的血清样品所测得的呼吸道合胞病毒株A2(RSV A2)VNA滴度。每个点代表一只小鼠;条代表组平均值,虚线对应于定量下限(LLOQ=6,88;线性样品的平均终点滴度)。结果表明,用Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc以1010vp剂量免疫所产生的RSV A2中和滴度与编码相同抗原的基准Ad26载体所见的中和滴度相似。主要在用于免疫的最高剂量1010vp下检测到由所有三个载体Ad26、编码RSVF-2A-GLuc的Ad26HVRPtr12和Ad26HVRPtr13所诱导的滴度。正如预期的那样,未检测到针对编码萤火虫萤光素酶的相应腺病毒载体的RSV A2特异性应答。
通过RSV-FA2特异性ELISPOT试验评估了针对载体编码的抗原的细胞免疫诱导。为此,在免疫后八周时,分离来自免疫小鼠的脾细胞,用跨越RSV-FA2蛋白的15mer重叠肽刺激过夜,通过离体ELISPOT试验测定细胞免疫应答,该试验测量IFN-γ分泌细胞的相对数量。数据显示,由编码RSVF-2A-GLuc的新型载体Ad26HVRPtr12和Ad26HVRPtr13引发的抗原特异性细胞免疫应答是剂量依赖性的,并且根据剂量,在大小上与基准载体Ad26.RSVF-2A-GLuc诱导的免疫应答分别更高和相似(图6C)。正如预期的那样,从用编码萤火虫萤光素酶的腺病毒载体免疫的小鼠的脾细胞中没有测量到RSVF-FA2特异性应答。
通过ELISA评估了表达RSVF-2A-GLuc的载体引发RSV-FA2特异性IgG抗体的能力。在抗RSV FA2 IgG抗体ELISA中测试了从用表达RSVF-2A-GLuc转基因或萤火虫萤光素酶(对照)的Ad26(阳性对照)、Ad26HVRPtr12、Ad26HVRPtr13免疫的小鼠免疫后8周时收集的血清。具体而言,此ELISA检测能够结合重组稳定的融合前RSV-FA2蛋白(前RSV-F)的IgG抗体。结果表明,Ad26HVRPtr12.RSVF-2A-GLuc和Ad26HVRPtr13.RSVF-2A-GLuc以剂量依赖性方式引发了与Ad26.RSVF-2A-GLuc诱导的相似的前RSV-F特异性IgG抗体滴度(图6D)。正如预期的那样,在仅用编码萤火虫萤光素酶的载体免疫的小鼠的血清中未检测到RSV-FA2特异性抗体滴度。该图描绘以终点滴度(log10)计算的IgG ELISA滴度。每个点代表一只小鼠;条代表组平均值,虚线代表计算为1,36log10的定量下限(LLOQ)。
总体而言,数据显示,新型Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体诱导了针对所编码的抗原的强有力的细胞和体液免疫应答,在大小上与基于HAdV-26的基准载体所诱导的相似或更高。这些免疫应答清楚地表明了Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体在小鼠中的强有力的免疫原性。
实例8:对新型和现有腺病毒载体之间的血清交叉中和的评估
由于它们作为新腺病毒疫苗载体的潜在用途,本文产生的新型Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体优选地在血清学上不同于目前已经开发作为疫苗载体(诸如基于人腺病毒血清型HAdV-5和HAdV-35的载体)的现有腺病毒载体。因此,在新型Ad26HVRPtr12和Ad26HVRPtr13腺病毒载体以及基于HAdV-4、HAdV-5、HAdV-26和HAdV-35的几种现有载体之间进行了交叉中和测试。为此,在腺病毒中和试验中,针对每种不同的载体测试小鼠抗血清,每种抗血清针对这些腺病毒载体之一而产生。在将Balb/C小鼠用每只小鼠1010个载体颗粒免疫后两周或八周时,从这些小鼠收集用于该试验的小鼠抗血清。如先前所述(Spangers等人2003.J.Clin.Microbiol.[临床微生物学杂志]41:5046-5052)进行腺病毒中和试验。简而言之,从1:16稀释开始,将血清进行2倍系列稀释,然后与表达萤火虫萤光素酶(FLuc)的腺病毒载体预混合,然后与A549细胞温育过夜(以每个细胞500个病毒颗粒的感染复数)。感染后24小时测得的被感染细胞裂解物中的萤光素酶活性水平代表载体感染效率。针对给定载体的中和滴度定义为能够使载体感染效率降低90%的最高血清稀释度。中和滴度可任意分为以下几类:<16(无中和)、16至200、200至2,000和>2,000。
结果表明,在所测试的载体之间没有或只有极低水平的交叉中和(图7)。观察到Ad26HVRPtr12对Ad26和Ad26HVRPtr13载体以及Ad26HVRPtr13对Ad26和Ad26HVRPtr12载体的轻微交叉中和作用。对于这些载体观察到的相互交叉中和滴度明显低于对于这些相同载体所获得的相应的同源中和滴度。重要的是,除了Ad26观察到非常低水平的交叉中和外,新型Ad26HVRPtr12和Ad26HVRPtr13载体未显示出与测试组中的人腺病毒载体(即Ad35、Ad5和Ad4)的交叉中和。因此,这些新腺病毒载体Ad26HVRPtr12和Ad26HVRPtr13各自可以潜在地与一种或多种这些或其他不同的腺病毒载体联合用于顺序免疫,例如在异源初免-加强疫苗接种方案的情况下,或者,可替代地或另外,在一系列针对不同疾病或抗原的两个或更多个连续疫苗接种方案的情况下。
实例9:新型腺病毒载体在人群中的血清阳性率
对于它们作为有效疫苗载体的潜在用途而言重要的是,本文所述的新型腺病毒载体不受疫苗目标群体中高水平的预先存在的抗载体体液免疫的妨碍。因此,在200个来自成年人的人群血清样品中评价了Ad26HVRPtr12和Ad26HVRPtr13载体各自的血清阳性率,这些成年人年龄为18-55岁,生活在美国(US)和欧盟(EU)。通过进行如实例7中所开展的且如先前所述的(Spangers等人2003.J.Clin.Microbiol.[临床微生物学杂志]41:5046-5052)标准腺病毒中和试验,测试了这些载体被人血清样品中和的情况。简而言之,从1:16稀释开始,将血清进行2倍系列稀释,然后与表达萤火虫萤光素酶(FLuc)的腺病毒载体预混合,然后与A549细胞温育过夜(以每个细胞500个病毒颗粒的感染复数)。感染后24小时测得的被感染细胞裂解物中的萤光素酶活性水平代表载体感染效率。针对给定载体的中和滴度定义为能够使载体感染效率降低90%的最高血清稀释度。中和滴度可任意分为以下几类:<16(无中和)、16至300、300至1000、1000至4000和>4000。
结果表明,在所研究的人类受试者中,腺病毒载体Ad26HVRPtr12和Ad26HVRPtr13的血清阳性率显著低于对照Ad5载体,并且在这些受试者中的血清阳性率与基准Ad26载体相似(图8)。此外,针对新型Ad26HVRPtr12和Ad26HVRPtr13载体的阳性中和滴度通常很低,大部分不高于300。相比之下,大多数针对Ad26和Ad5两者发现的阳性中和滴度高于300。
总体而言,上述数据表明,可以认为在所评估的疫苗目标群体中,针对Ad26HVRPtr12和Ad26HVRPtr13载体的预先存在的体液抗载体免疫是较低的,这表明这些载体在这些群体中具有作为有效疫苗载体的潜力。
实例10:在悬浮PER.C6细胞中的腺病毒载体生产率
用于临床试验及其他方面的腺病毒载体需要在可扩展的无血清腺病毒生产平台中容易地生产至高滴度。悬浮-适应的PER.细胞(本文也称为悬浮PER.C6细胞或sPER.C6)代表了这样的平台,因为它们已经显示出支持在生物反应器中大规模生产腺病毒载体,获得大量高滴度的临床级载体制备物,例如基于HAdV-26或HAdV-35的E1缺失型载体的制备物(EP 2536829B1、EP 2350268B1)。
作为关于本文所述的新型载体是否适合基于sPER.C6细胞的生产工艺的初步评估,对在摇瓶中培养的sPER.C6细胞进行了小规模载体生产率实验。这些生产率实验使用新型腺病毒载体Ad26HVRPtr12和Ad26HVRPtr13的Fluc编码形式(实例4中所述)进行。基于HAdV-26的载体Ad26.Fluc用作基准对照。将以1×106个细胞/ml的密度接种在摇瓶中的总体积为10ml的补充了4mM L-谷氨酰胺(龙沙集团(Lonza))的培养基(可从龙沙集团获得)中的悬浮PER.C6细胞培养物用不同的载体以不同的病毒颗粒(VP)-细胞比感染,然后温育4天。用于感染的不同VP-细胞比是70、150和900。每天采集被感染的细胞培养物的样品,并通过基于定量PCR(qPCR)的方案测定这些样品中的VP滴度,该方案采用对CMV启动子(其存在于所有测试的载体中)特异的引物和探针。该方案需要在qPCR之前对测试样品进行DNA酶处理,以除去任何游离的载体DNA(即未包装到病毒颗粒中的载体基因组)。
嵌合载体Ad26HVRPtr12.FLuc和Ad26HVRPtr13所得的生产率结果如图9所示。这两个嵌合载体产生的VP滴度等于亲本基准载体Ad26.Fluc获得的VP滴度。因此,这些结果证明了每种新型嵌合载体在基于sPER.C6的无血清悬浮细胞培养模型上的良好生产率。
总之,如上所述,对本发明的新型重组腺病毒载体的体液和细胞免疫应答进行的研究清楚地表明这些载体在小鼠中的强有力的免疫原性。此外,这些载体被证明不诱导或诱导非常低的针对某些现有腺病毒疫苗载体候选物(例如Ad26和Ad35)的交叉中和抗体应答,反之亦然;以及仅诱导非常低的针对彼此的交叉中和抗体应答。此外,这些新载体在人类中显示出低血清阳性率。最后,这些新载体可以容易地以高产率产生。低血清阳性率、强有力的免疫原性和可生产性的组合表明本发明的新型腺病毒载体可用作针对多种病原体的新型疫苗载体候选物,并且可另外用于基因疗法和/或诊断。
本领域技术人员将理解,在不偏离本发明的广泛发明构思的情况下,可以对上述实施例进行改变。因此,应当理解,本发明不限于所披露的特定实施例,而是旨在涵盖由本说明书限定的本发明的精神和范围内的修改。
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<110> 扬森疫苗与预防公司
<120> 腺病毒载体及其用途
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Arg Trp Ser Leu Asp Pro Met Asp Asn Val Asn Pro Phe Asn His His
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Asn Leu Leu Leu Leu Pro Gly Ser Tyr Thr Tyr Glu Trp Asn Phe Arg
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Val Asp Gly Ala Ser Val Arg Phe Asp Ser Val Asn Leu Tyr Ala Thr
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Phe Phe Pro Met Ala His Asn Thr Ala Ser Thr Leu Glu Ala Met Leu
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Arg Asn Asp Thr Asn Asp Gln Ser Phe Asn Asp Tyr Leu Ser Ala Ala
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Arg Ser Val Asp Gly Glu Gly Tyr Asn Val Ala Gln Cys Asn Met Thr
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Lys Asp Trp Phe Leu Val Gln Met Leu Ser His Tyr Asn Ile Gly Tyr
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Phe Arg Asn Phe Gln Pro Met Ser Arg Gln Val Val Asp Glu Ile Asn
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Tyr Lys Asp Tyr Lys Ala Val Thr Leu Pro Phe Gln His Asn Asn Ser
805 810 815
Gly Phe Thr Gly Tyr Leu Ala Pro Thr Met Arg Gln Gly Gln Pro Tyr
820 825 830
Pro Ala Asn Phe Pro Tyr Pro Leu Ile Gly Gln Thr Ala Val Pro Ser
835 840 845
Val Thr Gln Lys Lys Phe Leu Cys Asp Arg Val Met Trp Arg Ile Pro
850 855 860
Phe Ser Ser Asn Phe Met Ser Met Gly Ala Leu Thr Asp Leu Gly Gln
865 870 875 880
Asn Met Leu Tyr Ala Asn Ser Ala His Ala Leu Asp Met Thr Phe Glu
885 890 895
Val Asp Pro Met Asp Glu Pro Thr Leu Leu Tyr Leu Leu Phe Glu Val
900 905 910
Phe Asp Val Val Arg Val His Gln Pro His Arg Gly Val Ile Glu Ala
915 920 925
Val Tyr Leu Arg Thr Pro Phe Ser Ala Gly Asn Ala Thr Thr
930 935 940
<210> 5
<211> 28263
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr12
<400> 5
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg aaggtaggtt 480
tgagtagtgg gcgtggctaa ggtgactata aaggcgggtg tcttacgagg gtctttttgc 540
ttttctgcag acatcatgaa cgggactggc ggggccttcg aaggggggct ttttagccct 600
tatttgacaa cccgcctgcc gggatgggcc ggagttcgtc agaatgtgat gggatcgacg 660
gtggatgggc gcccagtgct tccagcaaat tcctcgacca tgacctacgc gaccgtgggg 720
aactcgtcgc tcgacagcac cgccgcagcc gcggcagccg cagccgccat gacagcgacg 780
agactggcct cgagctacat gcccagcagc ggtagtagcc cctctgtgcc cagttccatc 840
atcgccgagg agaaactgct ggccctgctg gccgagctgg aagccctgag ccgccagctg 900
gccgccctga cccagcaggt gtccgagctc cgcgaacagc agcagcagca aaataaatga 960
ttcaataaac acagattctg attcaaacag caaagcatct ttattattta ttttttcgcg 1020
cgcggtaggc cctggtccac ctctcccgat cattgagagt gcggtggatt ttttccagga 1080
cccggtagag gtgggattgg atgttgaggt acatgggcat gagcccgtcc cgtgggtgga 1140
ggtagcacca ctgcatggcc tcgtgctctg gggtcgtgtt gtagatgatc cagtcatagc 1200
aggggcgctg ggcgtggtgc tggatgatgt ccttgaggag gagactgatg gccacgggga 1260
gccccttggt gtaggtgttg gcaaaacggt tgagctggga gggatgcatg cggggggaga 1320
tgatgtgcag tttggcctgg atcttgaggt tggcgatgtt gccacccaga tcccgccggg 1380
ggttcatgtt gtgcaggacc accagaacgg tgtagcccgt gcacttgggg aacttgtcat 1440
gcaacttgga agggaatgcg tggaagaatt tggagacgcc cttgtgcccg cccaggtttt 1500
ccatgcactc atccatgatg atggcaatgg gcccgtgggc tgcggctttg gcaaagacgt 1560
ttctggggtc agagacatcg taattatgct cctgggtgag atcatcataa gacattttaa 1620
tgaatttggg gcggagggtg ccagattggg ggacgatggt tccctcgggc cccggggcga 1680
agttcccctc gcagatctgc atctcccagg ctttcatctc ggaggggggg atcatgtcca 1740
cctgcggggc gatgaaaaaa acggtttccg gggcgggggt gatgagctgc gaggagagca 1800
ggtttctcaa cagctgggac ttgccgcacc cggtcgggcc gtagatgacc ccgatgacgg 1860
gttgcaggtg gtagttcaag gacatgcagc tgccgtcgtc ccggaggagg ggggccacct 1920
cgttgagctt gtctctgact tggaggtttt cccggacgag ctcgccgagg aggcggtccc 1980
cgcccagcga gagaagctct tgcagggaag caaagttttt caggggcttg agcccgtcgg 2040
ccatgggcat cttggcgagg gtctgcgaga ggagctccag gcggtcccag agctcggtga 2100
cgtgctctac ggcatctcga tccagcagac ttcctcgttt cgggggttgg gacgactgcg 2160
actgtagggc acgagacgat gggcgtccag cgcggccagc gtcatgtcct tccagggtct 2220
cagggtccgc gtgagggtgg tctccgtcac ggtgaagggg tgggccgcgg gctgggcgct 2280
tgcaagggtg cgcttgagac tcatcctgct ggtgctgaaa cgggcacggt cttcgccctg 2340
cgcgtcggcg agatagcagt tgaccatgag ctcgtagttg agggcctcgg cggcgtggcc 2400
cttggcgcgg agcttgccct tggaagagcg cccgcaggcg ggacagagga gggattgcag 2460
ggcgtagagc ttgggcgcga gaaagacgga ctcgggggcg aaggcgtccg ctccgcagtg 2520
ggcgcagacg gtctcgcact cgactagcca ggtgagctcg ggctgctcgg ggtcaaaaac 2580
cagttttccc ccgttctttt tgatgcgctt cttacctcgc gtctccatga gtctgtgtcc 2640
gcgctcggtg acaaacaggc tgtctgtgtc cccgtagacg gacttgatgg gcctgtcctg 2700
caggggcgtc ccgcggtcct cctcgtagag aaactcagac cactctgaga cgaaggcgcg 2760
cgtccacgcc aagacaaagg aggccacgtg cgaggggtag cggtcgttgt ccaccagggg 2820
gtccaccttt tccacggtat gcaggcacat gtccccctcc tccgcatcca agaaggtgat 2880
tggcttgtag gtgtaggcca cgtgacctgg ggttcccgac gggggggtat aaaagggggc 2940
gggtctgtgc tcgtcctcac tctcttccgc gtcgctgtcc acgagcgcca gctgttgggg 3000
taggtattcc ctctcaagag cgggcatgac ctcggcactc aggttgtcag tttctagaaa 3060
cgaggaggat ttgatgtggg cctgccctgc cgcgatgctt tttaggagac tttcatccat 3120
ctggtcagaa aagactattt ttttattgtc aagcttggtg gcgaaggagc catagagggc 3180
gtttgagaga agcttggcga tggatctcat ggtctgattt ttgtcacggt cggcgcgctc 3240
cttggccgcg atgttgagct ggacatattc gcgcgcgaca cacttccatt cggggaagac 3300
ggtggtgcgc tcgtcgggca cgatcctgac gcgccagccg cggttatgca gggtgaccag 3360
gtccacgctg gtggccacct cgccgcgcag gggctcgttg gtccagcaga gtctgccgcc 3420
cttgcgcgag cagaacgggg gcagcacatc aagcagatgc tcgtcagggg ggtccgcatc 3480
gatggtgaag atgcccggac agagttcctt gtcaaaataa tcgatttttg aggatgcatc 3540
gtccaaggcc atctgccact cgcgggcggc cagcgctcgc tcgtaggggt tgaggggcgg 3600
accccaaggc atgggatgcg tgagggcgga ggcgtacatg ccgcagatgt catagacata 3660
gatgggctcc gagaggatgc cgatgtaggt gggatagcag cgccccccgc ggatgcttgc 3720
gcgcacgtag tcatacaact cgtgcgaggg ggccaagaag gcggggccga gattggtgcg 3780
ctggggctgc tcggcgcgga agacgatctg gcgaaagatg gcgtgcgagt tggaggagat 3840
ggtgggccgt tggaagatgt taaagtgggc gtgaggcagg cggaccgagt cgcggatgaa 3900
gtgcgcgtag gagtcttgca gcttggcgac gagctcggcg gtgacgagga cgtccatggc 3960
gcagtagtcc agcgtttcgc ggatgatgtc ataactcgcc tctcctttct tctcccacag 4020
ctcgcggttg agggcgtatt cctcgtcatc cttccagtac tcccggagcg ggaatcctcg 4080
atcgtccgca cggtaagagc ccagcatgta gaaatggttc acggccttgt agggacagca 4140
gcccttctcc acggggaggg cgtaagcttg agcggccttg cggagcgagg tgtgcgtcag 4200
ggcaaaggtg tccctgacca tgactttcaa gaactggtac ttgaagtccg agtcgtcgca 4260
gccgccgtgc tcccagagct cgaaatcggt gcgcttcttc gagagggggt taggcagagc 4320
gaaagtgacg tcattgaaga gaatcttgcc tgcccgcggc atgaaattgc gggtgatgcg 4380
gaaagggccc gggacggagg ctcggttgtt gatgacctgg gcggcgagga cgatctcgtc 4440
aaagccgttg atgttgtgcc cgacgatgta gagttccatg aatcgcgggc ggcctttgat 4500
gtgcggcagc tttttgagct cctcgtaggt gaggtcctcg gggcattgca ggccgtgctg 4560
ctcgagcgcc cactcctgga gatgtgggtt ggcttgcatg aaggaagccc agagctcgcg 4620
ggccatgagg gtctggagct cgtcgcgaaa gaggcggaac tgctggccca cggccatctt 4680
ttctggggtg acgcagtaga aggtgagggg gtcccgctcc cagcgatccc agcgtaaacg 4740
cacggcgaga tcgcgagcga gggcgaccag ctctgggtcc ccggagaatt tcatgaccag 4800
catgaagggg acgagctgct tgccgaagga ccccatccag gtgtaggttt ctacatcgta 4860
ggtgacaaag agccgctccg tgcgaggatg agagccgatt gggaagaact ggatttcctg 4920
ccaccagttg gacgagtggc tgttgatgtg atgaaagtag aaatcccgcc ggcgaaccga 4980
gcactcgtgc tgatgcttgt aaaagcgtcc gcagtactcg cagcgctgca cgggctgtac 5040
ctcatccacg agatacacag cgcgtccctt gaggaggaac ttcaggagtg gcggccctgg 5100
ctggtggttt tcatgttcgc ctgcgtggga ctcaccctgg ggctcctcga ggacggagag 5160
gctgacgagc ccgcgcggga gccaggtcca gatctcggcg cggcgggggc ggagagcgaa 5220
gacgagggcg cgcagttggg agctgtccat ggtgtcgcgg agatccaggt ccgggggcag 5280
ggttctgagg ttgacctcgt agaggcgggt gagggcgtgc ttgagatgca gatggtactt 5340
gatttctacg ggtgagttgg tggtcgtgtc cacgcattgc atgagcccgt agctgcgcgg 5400
ggccacgacc gtgccgcggt gcgcttttag aagcggtgtc gcggacgcgc tcccggcggc 5460
agcggcggtt ccggccccgc gggcaggggc ggcagaggca cgtcggcgtg gcgctcgggc 5520
aggtcccggt gctgcgccct gagagcgctg gcgtgcgcga cgacgcggcg gttgacatcc 5580
tggatctgcc gcctctgcgt gaagaccacg ggccccgtga ctttgaacct gaaagacagt 5640
tcaacagaat caatctctgc gtcattgacg gcggcctgac gcaggatctc ttgcacgtcg 5700
cccgagttgt cctggtaggc gatctcggac atgaactgtt cgatctcctc ctcctggaga 5760
tcgccgcggc ccgcgcgctc cacggtggcg gcgaggtcat tggagatgcg acccatgagc 5820
tgcgagaagg cgcccaggcc gctctcgttc cagacgcggc tgtagaccac gtccccgtcg 5880
gcgtcgcgcg cgcgcatgac cacctgcgcg aggttgagct ccacgtgccg cgcaaagacg 5940
gcgtagttgc gcaggcgctg gaagaggtag ttgagggtgg tggcgatgtg ctcggtgacg 6000
aagaagtaca tgatccagcg gcgcaggggc atctcgctga tgtcgccgat ggcttccagc 6060
ctttccatgg cctcgtagaa gtccacggcg aagttgaaaa actgggcgtt gcgggccgag 6120
accgtgagct cgtcttccag gagccggatg agttcggcga tggtggcgcg cacctcgcgc 6180
tcgaaatccc cgggggcctc ctcctcttcc tcttcttcca tgacgacctc ttcttctatt 6240
tcttcctctg ggggcggtgg tggtggcggg ggccgacgac gacggcgacg caccgggaga 6300
cggtcgacga agcgctcgat catctccccg cggcggcgac gcatggtttc ggtgacggcg 6360
cgaccccgtt cgcgaggacg cagcgtgaag acgccgccgg tcatctcccg gtaatggggc 6420
gggtccccat tgggcagcga tagggcgctg acgatgcatc ttatcaattg cggtgtaggg 6480
gacgtgagcg cgtcgagatc gaccggatcg gagaatcttt cgaggaaagc gtctagccaa 6540
tcgcagtcgc aaggtaagct caaacacgta gcagccctgc ggacgctgtt agaattgcgg 6600
ttgctgatga tgtaattgaa gtaggcgttt ttgaggcggc ggatggtggc gaggaggacc 6660
aggtccttgg gtccagcttg ctggatgcgg agccgctcgg ccatgcccca ggcctggccc 6720
tgacaccggc tcaggttctt gtagtagtca tgcatgagcc tctcaatgtc atcactggct 6780
gaggcggagt cttccatgcg ggtgaccccg acgcccctga gcggctgcac gagcgccagg 6840
tcggcgacga cgcgctcggc gaggatggcc tgttgcacgc gggtgagggt gtcctggaag 6900
tcgtccatgt cgacgaagcg gtgataggcc ccggtgttga tggtgtaggt gcagttggcc 6960
atgagcgacc agttgacggt ctgcaggcct ggctgcacga cctcggagta cctgagccgc 7020
gagaaggcgc gcgagtcgaa gacgtagtcg ttgcaggtgc gcacgaggta ctggtatccg 7080
actaggaagt gcggcggcgg ctggcggtag agcggccagc gctgggtggc cggcgcgccc 7140
ggggccaggt cctcgagcat gaggcggtgg tagccgtaga ggtagcggga catccaggtg 7200
atgccggcgg cggtggtgga ggcgcgcggg aactcgcgga cgcggttcca gatgttgcgc 7260
agcggcagga aatagtccat ggtcggcacg gtctggccgg tgagacgcgc gcagtcattg 7320
acgctctaga ggcaaaaacg aaagcggttg agcgggctct tcctccgtag cctggcggaa 7380
cgcaaacggg ttaggccgcg tgtgtacccc ggttcgagtc ccctcgaatc aggctggagc 7440
cgcgactaac gtggtattgg cactcccgtc tcgacccgag cccgatagcc gccaggatac 7500
ggcggagagc cctttttgcc ggccgagtgg ggtcgctaga cttgaaagcg accgaaaacc 7560
ctgccgggta gtggctcgcg cccgtagtct ggagaagcat cgccagggtt gagtcgcggc 7620
agaacccggt tcgaggacgg ccgcggcgag cgggacttgg tcaccccgcc gatataaaga 7680
cccacagcca gccgacttct ccagttacgg gagcgagccc ccttttttct ttttgccaga 7740
tgcatcccgt cctgcgccaa atgcgtccca cccccccggc gaccaccgcg accgcggccg 7800
tagcaggcgc cggcgctagc cagccaccac agacagagat ggacttggaa gagggcgaag 7860
ggctggcaag actgggggcg ccgtccccgg agcgacatcc ccgcgtgcag ctgcagaagg 7920
acgtgcgccc ggcgtacgtg cctacgcaga acctgttcag ggaccgcagc ggggaggagc 7980
ccgaggagat gcgcgactgc cggtttcggg cgggcaggga gctgcgcgag ggcctggacc 8040
gccagcgcgt gctgcgcgac gaggatttcg agccgaacga gcagacgggg atcagccccg 8100
cacgcgcgca cgtggcggca gccaacctgg tgacggccta cgagcagacg gtgaagcagg 8160
agcgcaactt ccaaaagagt ttcaacaacc acgtgcgcac cctgatcgcg cgcgaggagg 8220
tggccctggg cctgatgcac ctgtgggacc tggcggaggc catcgtgcag aacccggaca 8280
gcaagcctct gacggcgcag ctgttcctgg tggtgcagca cagcagggac aacgaggcgt 8340
tcagggaggc gctgctgaac atcgccgagc ccgagggtcg ctggctgctg gagctgatta 8400
acatcttgca gagcatcgta gtgcaggagc gcagcctgag cctggccgag aaggtggcgg 8460
cgatcaacta ctcggtgctg agcctgggca agttttacgc gcgcaagatt tacaagacgc 8520
cgtacgtgcc catagacaag gaggtgaaga tagacagctt ttacatgcgc atggcgctca 8580
aggtgctgac gctgagcgac gacctgggcg tgtaccgcaa cgaccgcatc cacaaggccg 8640
tgagcacgag ccggcggcgc gagctgagcg accgcgagct gatgctgagt ctgcgccggg 8700
cgctggtagg gggcgccgcc ggcggcgagg agtcctactt cgacatgggt gcggacctgc 8760
attggcagcc gagccggcgc gccttggagg ccgcctacgg ttcagaggac ttggatgagg 8820
aagaggaaga ggaggaggat gcacccgctg cggggtactg acgcctccgt gatgtgtttt 8880
tagatgtccc agcaagcccc ggaccccgcc ataagggcgg cgctgcaaag ccagccgtcc 8940
ggtctagcat cggacgactg ggaggccgcg atgcaacgca tcatggccct gacgacccgc 9000
aaccccgagt cctttagaca acagccgcag gccaacagac tctcggccat tctggaggcg 9060
gtggtcccct ctcggaccaa ccccacgcac gagaaggtgc tggcgatcgt gaacgcgctg 9120
gcggagaaca aggccatccg tcccgacgag gccgggctgg tgtacaacgc cctgctggag 9180
cgcgtgggcc gctacaacag cacgaacgtg cagtccaacc tggatcggct ggtgacggac 9240
gtgcgcgagg ccgtggcgca gcgcgagcgg ttcaagaacg agggcctggg ctcgctggtg 9300
gcgctgaacg ccttcctggc gacgcagccg gcgaacgtgc cgcgcgggca ggacgattac 9360
accaacttta tcagcgcgct gcggctgatg gtgaccgagg tgccccagag cgaggtgtac 9420
cagtctggcc cggactactt tttccagacg agccggcagg gcttgcagac ggtgaacctg 9480
agccaggctt tcaagaatct gcgcgggctg tggggcgtgc aggcgcccgt gggcgaccgg 9540
tcaacggtga gcagcttgct gacgcccaac tcgcggctgc tgctgctgct gatcgcgccc 9600
ttcaccgaca gcggcagcgt gaaccgcaac tcgtacctgg gccatctgct gacgctgtac 9660
cgcgaggcca taggccaggc gcaggtggac gagcagacct tccaggagat cactagcgtg 9720
agccgcgcgc tggggcagaa cgacaccgac agtctgaggg ccaccctgaa ctttttgctg 9780
accaatagac agcagaagat cccggcgcag tacgcactgt cggccgagga ggaaaggatt 9840
ctgagatatg tgcagcagag cgtagggctg ttcctgatgc aggagggtgc cacccccagc 9900
gccgcgctgg acatgaccgc gcgcaacatg gaacctagca tgtacgccgc caaccggccg 9960
ttcatcaata agctgatgga ctacttgcac cgcgcggcgg ccatgaacac ggactacttt 10020
accaacgcca tcctgaaccc gcactggctc ccgccgccgg ggttctacac gggcgagtac 10080
gacatgcccg accccaacga cgggttcctg tgggacgacg tggacagcgc ggtgttctcg 10140
ccgacctttc aaaagcgcca ggaggcgccg ccgagcgagg gcgcggtggg gaggagcccc 10200
tttcctagct tagggagttt gcatagcttg ccgggctcgg tgaacagcgg cagggtgagc 10260
cggccgcgct tgctgggcga ggacgagtac ctgaacgact cgctgctgca gccgccgcgg 10320
gccaagaacg ccatggccaa taacgggata gagagtctgg tggacaaact gaaccgctgg 10380
aagacctacg ctcaggacca tagggacgcg cccgcgccgc ggcgacagcg ccacgaccgg 10440
cagcggggcc tggtgtggga cgacgaggac tcggccgacg atagcagcgt gttggacttg 10500
ggcgggagcg gtggggtcaa cccgttcgcg catctgcagc ccaaactggg gcgacggatg 10560
ttttgaatga aataaaactc accaaggcca tagcgtgcgt tctcttcctt gttagagatg 10620
aggcgcgcgg tggtgtcttc ctctcctcct ccctcgtacg agagcgtgat ggcgcaggcg 10680
accctggagg ttccgtttgt gcctccgcgg tatatggctc ctacggaggg cagaaacagc 10740
attcgttact cggagctggc tccgcagtac gacaccactc gcgtgtactt ggtggacaac 10800
aagtcggcgg acatcgcttc cctgaactac caaaacgacc acagcaactt cctgaccacg 10860
gtggtgcaga acaacgattt cacccccgcc gaggccagca cgcagacgat aaattttgac 10920
gagcggtcgc ggtggggcgg tgatctgaag accattctgc acactaacat gcccaatgtg 10980
aacgagtaca tgttcaccag caagtttaag gcgcgggtga tggtgtctag gaagcatcca 11040
gagggggtag ttgaaacaga tttgagtcag gataagcttg aatatgagtg gtttgagttt 11100
accctgcccg agggaaactt ttccgagacc atgaccatag acctgatgaa caacgccatc 11160
ttggaaaact acttgcaagt ggggcggcag aatggcgtgc tggagagcga tatcggagtc 11220
aagtttgaca gcagaaattt caagctgggc tgggacccgg tgaccaagct ggtgatgcca 11280
ggggtctaca cctacgaggc cttccacccg gacgtggtgc tgctgccggg ctgcggggtg 11340
gacttcaccg agagccgcct gagcaacctc ctgggcattc gcaagaagca acctttccaa 11400
gagggcttca gaatcatgta tgaggatcta gaaggtggca acatccccgc cctccttgat 11460
gtgcccaagt acttggaaag caagaagaaa gttgaagacg aaactaaaaa tgcagctgcg 11520
gccacagccg atacaaccac taggggtgat acatttgcaa ctccagcgca agagacagca 11580
gctgataaga aggtagaagt cttgcccatt gaaaaggatg agagtggtag aagttacaac 11640
ctgatccagg ggacccacga cacgctgtac cgcagttggt acctgtccta tacctacggg 11700
gaccccgaga agggggtgca gtcgtggacg ctgctcacca ccccggacgt tacctgcggc 11760
gcggagcaag tctactggtc actgccggac ctcatgcaag accccgtcac cttccgctcc 11820
acccagcaag tcagcaacta ccccgtggtc ggcgccgagc tcatgccctt ccgcgccaag 11880
agcttttaca acgacctcgc cgtctactcc cagctcatcc gcagctacac ctccctcacc 11940
cacgtcttca accgcttccc cgacaaccag atcctctgcc gcccgcccgc gcccaccatc 12000
accaccgtca gtgaaaacgt gcctgctctc acagatcacg ggacgctacc gctgcgcagc 12060
agtatccgcg gagtccagcg agtgaccgtc actgacgccc gtcgccgcac ctgtccctac 12120
gtctacaagg ccctgggcat agtcgcgccg cgcgtgcttt ccagtcgcac cttctaaaaa 12180
aatgtctatt ctcatctcgc ccagcaataa caccggctgg ggtcttacta gacccagcac 12240
catgtacgga ggagccaaga agcgctccca gcagcacccc gtccgcgtcc gcggccactt 12300
ccgcgctccc tggggcgcat acaagcgcgg gcggacttcc accgccgccg tgcgcaccac 12360
cgtcgacgac gtcatcgact cggtggtcgc cgacgcgcgc aactataccc ccgccccctc 12420
caccgtggac gcggtcatcg acagcgtggt ggccgacgcg cgcgactatg ccagacgcaa 12480
gagccggcgg cgacggatcg ccaggcgcca ccggagcacg cccgccatgc gcgccgcccg 12540
ggctctgctg cgccgcgcca gacgcacggg ccgccgggcc atgatgcgag ccgcgcgccg 12600
cgctgccact gcacccaccc ccgcaggcag gactcgcaga cgagcggccg ccgccgccgc 12660
tgcggccatc tctagcatga ccagacccag gcgcggaaac gtgtactggg tgcgcgactc 12720
cgtcacgggc gtgcgcgtgc ccgtgcgcac ccgtcctcct cgtccctgat ctaatgcttg 12780
tgtcctcccc cgcaagcgac gatgtcaaag cgcaaaatca aggaggagat gctccaggtc 12840
gtcgccccgg agatttacgg accaccccag gcggaccaga aaccccgcaa aatcaagcgg 12900
gttaaaaaaa aggatgaggt ggacgagggg gcagtagagt ttgtgcgcga gttcgctccg 12960
cggcggcgcg taaattggaa ggggcgcagg gtgcagcgcg tgttgcggcc cggcacggcg 13020
gtggtgttca cgcccggcga gcggtcctcg gtcaggagca agcgtagcta tgacgaggtg 13080
tacggcgacg acgacatcct ggaccaggcg gcggagcggg cgggcgagtt cgcctacggg 13140
aagcggtcgc gcgaagagga gctgatctcg ctgccgctgg acgaaagcaa ccccacgccg 13200
agcctgaagc ccgtgaccct gcagcaggtg ctgccccagg cggtgctgct gccgagccgc 13260
ggggtcaagc gcgagggcga gagcatgtac ccgaccatgc agatcatggt gcccaagcgc 13320
cggcgcgtgg aggacgtgct ggacaccgtg aaaatggatg tggagcccga ggtcaaggtg 13380
cgccccatca agcaggtggc gccgggcctg ggcgtgcaaa ccgtggacat tcagatcccc 13440
accgacatgg atgtcgacaa aaaaccctcg accagcatcg aggtgcaaac cgacccctgg 13500
ctcccagcct ccaccgctac cgtctccact tctaccgccg ccacggctac cgagcctccc 13560
aggaggcgaa gatggggcgc cgccagccgg ctgatgccca actacgtgtt gcatccttcc 13620
atcatcccga cgccgggcta ccgcggcacc cggtactacg ccagccgccg gcgcccagcc 13680
agcaaacgcc gccgccgcac cgccacccgc cgccgtctgg cccccgcccg cgtgcgccgc 13740
gtgaccacgc gccggggccg ctcgctcgtt ctgcccaccg tgcgctacca ccccagcatc 13800
ctttaatccg tgtgctgtga tactgttgca gagagatggc tctcacttgc cgcctgcgca 13860
tccccgtccc gaattaccga ggaagatccc gccgcaggag aggcatggca ggcagcggcc 13920
tgaaccgccg ccggcggcgg gccatgcgca ggcgcctgag tggcggcttt ctgcccgcgc 13980
tcatccccat aatcgccgcg gccattggca cgatcccggg catagcttcc gttgcgctgc 14040
aggcgtcgca gcgccgttga tgtgcgaata aagcctcttt agactctgac acacctggtc 14100
ctgtatattt ttagaatgga agacatcaat tttgcgtccc tggctccgcg gcacggcacg 14160
cggccgttca tgggcacctg gaacgagatc ggcaccagcc agctgaacgg gggcgccttc 14220
aattggagca gtgtctggag cgggcttaaa aatttcggct cgacgctccg gacctatggg 14280
aacaaggcct ggaatagtag cacggggcag ttgttgaggg aaaagctcaa agaccagaac 14340
ttccagcaga aggtggtgga cgggctggcc tcgggcatta acggggtggt ggacatcgcg 14400
aaccaggccg tgcagcgcga gataaacagc cgcctggacc cgcgaccgcc cacggtggtg 14460
gagatggaag atgcaactct tccgccgccc aagggcgaga agcggccgcg gcccgacgcg 14520
gaggagacga tcctgcaggt ggacgagccg ccctcgtacg aggaggccgt caaggccggc 14580
atgcccacca cgcgcatcat cgcgccgctg gccacgggtg taatgaaacc cgccaccctt 14640
gacctgcctc caccacccgc gcccgctcca ccgaaggcaa ctccggttgt gcaggccccc 14700
ccggtggcga ccgccgtgcg ccgcgtcccc gcccgccgcc aggcccagaa ctggcagagc 14760
acgctgcaca gtatcgtggg cctgggagtg aaaagtctga agcgccgccg atgctattga 14820
gagagaggaa agaggacact aaagggagag cttaacttgt atgtgcctta ccgccagaga 14880
acgcgcgaag atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg 14940
gcaggacgcc tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac 15000
gtacttcagc ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac 15060
cacggaccgg tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac 15120
gtactcgtac aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc 15180
cagcacttac tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc 15240
gggcacggcc tacaacagcc tggctcccaa gggtgccccc aatcccagcc agtgggagca 15300
aaatgaaacc aatgttaata aaacacacac ctttgggatg gcagccatga aaggagaagc 15360
tattgacaaa aatggtctgc aaattggaac tgacgcggcg gatcaggata aaccaattta 15420
tgcagataaa actttccagc cagaacctca agtaggagag gaagactgga ttgataaagc 15480
agatttctat ggcggaagag ctcttaaaaa agacactaaa atgaaaccat gctatggatc 15540
ttttgctaga cctactaatg agaaaggagg tcaggcaaag ttcaaaccag ttaatgaagg 15600
agaacaacct aaagatctgg atatagatat gaacttcttt gacccaacca ctattaacac 15660
accagatgta gtgctgtaca ctgaaaatgt taatcttgaa acaccagaca ctcatgtggt 15720
ttacaaggca ggaacttcag atgacagttc tgaggtcaat ttggctcagc agtccatgcc 15780
aaacagaccc aactacattg gctttaggga caactttgta ggtctcatgt attacaacag 15840
caccggaaat atgggtgtgc tggctggtca ggcttctcag ttgaacgctg tggtcgactt 15900
gcaagacaga aacaccgagt tatcttacca gctattgcta gattctctgg gtgacagaac 15960
cagatacttt agcatgtgga actctgcggt ggacagttac gatccagatg tcaggatcat 16020
tgaaaatcac ggtgtggaag atgaacttcc aaactattgc ttcccattgg atggtgtggg 16080
cactaatact gcataccaag gcgttaaagt taagacaact aatggaaacg acacgtggga 16140
aaaagatgaa actgtttatg agtttaatca aattggcaag ggggatatct atgccatgga 16200
gatcaacctg caggccaacc tgtggaagag ttttctgtac tcgaacgtgg ccctgtacct 16260
gcccgactcc tacaagtaca cgccggccaa cgtcaagctg cccgccaaca ccaacaccta 16320
cgagtacatg aacggccgcg tggtagcccc ctcgctggtg gacgcctaca tcaacatcgg 16380
cgcccgctgg tcgttggatc ccatggacaa cgtcaacccc ttcaaccacc accgcaatgc 16440
gggcctgcgc taccgctcca tgctgctggg caacggccgc tacgtgccct tccacatcca 16500
agtgccccaa aagttctttg ccatcaagaa cctgctcctg ctcccgggct cctacaccta 16560
cgagtggaac ttccgcaagg acgtcaacat gatcctgcag agttccctcg gcaacgacct 16620
gcgcgtcgac ggcgcctccg tccgcttcga cagcgtcaac ctatacgcca ctttcttccc 16680
catggcgcac aacaccgctt caaccttgga agccatgctg cgcaacgaca ccaacgacca 16740
gtccttcaac gactacctct cggccgccaa catgctctac cccatcccgg ccaaggccac 16800
caacgtgccc atctccatcc catcgcgcaa ctgggccgcc ttccgcggct ggagtttcac 16860
ccggctcaag accaaggaaa ctccttccct cggctcgggt ttcgacccct actttgtcta 16920
ctcgggctcc atcccctacc tcgacgggac cttctacctc aaccacacct tcaagaaggt 16980
ctccatcatg ttcgactcct cggtcagctg gcccggcaac gaccggctgc tcacgccgaa 17040
cgagttcgag atcaagcgca gcgtcgacgg ggagggctac aacgtggccc aatgcaacat 17100
gaccaaggac tggttcctcg tccagatgct ctcccactac aacatcggct accagggctt 17160
ccacgtgccc gagggctaca aggaccgcat gtactccttc ttccgcaact tccagcccat 17220
gagcaggcag gtggtcgatg agatcaacta caaggactac aaggccgtca ccctgccctt 17280
ccagcacaat aactcgggct tcaccggcta cctcgcaccc accatgcgcc aggggcagcc 17340
ctaccccgcc aacttcccct acccgctcat cggtcagaca gccgtgccct ccgtcaccca 17400
gaaaaagttc ctctgcgaca gggtcatgtg gcgcatcccc ttctccagca acttcatgtc 17460
catgggcgcc ctcaccgacc tgggtcagaa catgctctac gccaactcgg cccacgcgct 17520
cgacatgacc ttcgaggtgg accccatgga tgagcccacc ctcctctatc ttctcttcga 17580
agttttcgac gtggtcagag tacaccagcc gcaccgcggc gtcatcgagg ccgtctacct 17640
gcgcacgccc ttctccgccg gcaacgccac cacctaagca tgagcggctc cagcgaacga 17700
gagctcgcgg ccatcgtgcg cgacctgggc tgcgggccct actttttggg cacccacgac 17760
aagcgcttcc cgggctttct cgccggcgac aagctggcct gcgccatcgt caacacggcc 17820
ggccgcgaga ccggaggcgt gcactggctc gccttcggct ggaacccgcg ctcgcgcacc 17880
tgctacatgt tcgacccctt tgggttctcg gaccgccggc tcaagcagat ttacagcttc 17940
gagtacgagg ccatgctgcg ccgcagcgcc ctggcctcct cgcccgaccg ctgtctcagc 18000
ctcgagcagt ccactcagac cgtgcagggg cccgactccg ccgcctgcgg actcttctgt 18060
tgcatgttct tgcatgcctt cgtgcactgg cccgaccgac ccatggacgg aaaccccacc 18120
atgaacttgc tgacgggggt gcccaacggc atgctacaat cgccacaggt gctgcccacc 18180
ctcaggcgca accaggagga actctaccgc ttcctcgcgc gccactcccc ttactttcgc 18240
tcccaccgcg ccgccatcga acacgccacc gcttttgaca aaatgaaaca actgcgtgta 18300
tctcaataaa cagcactttt attttacatg cactggagta tatgcaagtt atttaaaagt 18360
cgaaggggtt ctcgcgctcg tcgttgtgcg ccgcgctggg gagggccacg ttgcggtact 18420
ggtacttggg ctgccacttg aactcgggga tcaccagttt gggcactggg gtctcgggga 18480
aggtctcgct ccacatgcgc cggctcatct gcagggcgcc cagcatgtcc ggggcggaga 18540
tcttgaaatc gcagttgggg ccggtgctct gcgcgcgcga gttgcggtac acggggttgc 18600
agcactggaa caccatcaga ctggggtact tcacactagc cagcacgctc ttgtcgctga 18660
tctgatcctt gtccagatcc tcggcgttgc tcaggccgaa cggggtcatc ttgcacagct 18720
ggcgtcccag gaagggcacg ctctgaggct tgtggttaca ctcgcagtgc acgggcatca 18780
gcatcatccc cgcgccgcgc tgcatattcg ggtagagggc cttgacaaag gccgcgatct 18840
gcttgaaagc ttgctgggcc ttggccccct cgctgaaaaa caggccgcag ctcttcccgc 18900
tgaactggtt attcccacac ccggcatcct gcacgcagca gcgcgcgtca tggctggtca 18960
gttgcaccac gctccgtccc cagcggttct gggtcacctt agccttgctg ggctgctcct 19020
tcaacgcgcg ctgcccgttc tcgctggtca catccatctc caccacgtgg tccttgtgga 19080
tcatcatcgt cccgtgcaga cacttgagct ggccttccac ctcggtgcag ccgtgatccc 19140
acagggcgca accggtgcac tcccagttct tgtgcgcaat cccgctgtgg ctgaagatgt 19200
aaccttgcaa catgcggccc atgatggtgc taaatgcttt ctgggtggtg aaggtcagtt 19260
gcatcccgcg ggcctcctcg ttcatccagg tctggcacat cttctggaag atctcggtct 19320
gctcgggcat gagcttgtaa gcatcgcgca ggccgctgtc gacgcggtag cgttccatca 19380
gcacgttcat ggtatccatg cccttctccc aggacgagac cagaggcaga ctcagagggt 19440
tgcgtacgtt caggacaccg ggggtcgcgg gctcgacgat gcgttttccg tccttgcctt 19500
ccttcaatag aaccggcggc tggctgaatc ccactcccac gatcacggca tcttcctggg 19560
gcatctcttc gtcggggtct accttggtca catgcttggt ctttctggct tgcttctttt 19620
ttggagggct gtccacgggg agcacgtcct cctcggaaga cccggagccc acccgctgat 19680
actttcggcg cttggtgggc agaggaggtg gcggcgaggg gctcctctcc tgctccggcg 19740
gatagcgcgc cgacccgtgg ccccggggcg gagtggcctc tcggcccatg aaccggcgca 19800
cgtcctgact gccgccggcc attgtttcct aggggaagat ggaggagcag ccgcgtaagc 19860
aggagcagga ggaggactta accacccacg agcaacccaa aatcgagcag gacctgggct 19920
tcgaagagcc ggctcgtcta gaacccccac aggatgaaca ggagcacgag caagacgcag 19980
gccaggagga gaccgacgct gggctcgagc atggctacct gggaggagag gaggatgtgc 20040
tgctgaaaca cctgcagcgc cagtccctca tcctccggga cgccctggcc gaccggagcg 20100
aaacccccct cagcgtcgag gagctgtgtc gggcctacga gctcaacctc ttctcgccgc 20160
gcgtaccccc caaacgccag cccaacggca cctgcgagcc caacccgcgt ctcaacttct 20220
atcccgtctt tgcggtcccc gaagccctcg ccacctatca catctttttc aagaaccaaa 20280
agatccccgt ctcctgccgc gccaaccgca ccagcgccga cgcgctcctc gctttggggc 20340
ccggcgcgcg catacctgat atcgcttccc tggaagaggt gcccaagatc ttcgaagggc 20400
tcggtcggga cgagacgcgc gcggcgaacg ctctgaaaga aacagcagag gaagagggtc 20460
acactagcgc cctggtagag ttggaaggcg acaacgccag gctggccgtg ctcaagcgca 20520
gcgtcgagct tacccacttc gcctaccccg ccgtcaacct cccgcccaag gtcatgcgtc 20580
gcatcatgga tcagctcatc atgccccaca tcgaggccct cgatgaaagt caggagcagc 20640
gccccgagga cgcccggccc gtggtcagcg acgagatgct cgcgcgctgg ctcgggaccc 20700
gcgaccccca ggctttggaa cagcggcgca aactcatgct ggccgtggtc ctggtcaccc 20760
ttgagctcga atgcatgcgc cgctttttca gcgaccccga gaccctgcgc aaggtcgagg 20820
agaccctgca ctacactttc aggcacggtt tcgtcaggca ggcctgcaag atctccaacg 20880
tggagctgac caacctggtc tcctgcctgg ggatcctgca cgagaaccgc ctgggccaga 20940
ccgtgctcca ctctaccctg aagggcgagg cgcggcggga ctatgtccgc gactgcgtct 21000
ttctctttct ctgccacaca tggcaagcgg ccatgggcgt gtggcagcag tgtctcgagg 21060
acgagaacct aaaggagctg gacaagcttc ttgctagaaa ccttaaaaag ctgtggacgg 21120
gcttcgacga gcgcaccgtc gcctcggacc tggccgagat cgtcttcccc gagcgcctga 21180
gacagacgct gaaaggcggg ctgcccgact tcatgagcca gagcatgttg caaaactacc 21240
gcactttcat tcttgagcga tcaggcatcc tgcccgccac ctgcaacgcc ttcccctccg 21300
actttgtacc gctgagctac cgcgagtgtc ccccgccgct gtggagccac tgctacctct 21360
tgcagctggc caactacatc gcctaccact cggacgtgat cgaggacgtg agcggcgagg 21420
ggctgctcga gtgccactgt cgctgcaacc tgtgctcccc gcatcgctcc ctggtctgca 21480
acccccagct cctgagcgag acccaggtca tcggtacctt cgagctgcaa ggtccgcagg 21540
agtccaccgc tccgctgaaa ctcacgccgg ggttgtggac ttccgcgtac ctgcgcaaat 21600
ttgtacccga agactaccac gcccatgaga taaagttctt tgaggaccaa tcgcgtccgc 21660
agcacgcgga tctcacggcc tgcgtcatca cccagggcgc gatcctcgcc caattgcacg 21720
ccatccaaaa atcccgccaa gagtttcttc tgaaaaaggg tagaggggtc tacctggacc 21780
cccagacggg cgaggtgctc aacccgggtc tcccccagca tgccgaggaa gaagcaggag 21840
ccgctagtgg aggagatgga agaagaatgg gacagccagg cagaggagga cgaatgggag 21900
gaggagacag aggaggaaga attggaagag gtggaagagg agcaggcaac agagcagccc 21960
gtcgccgcac catccgcgcc ggcagccccg ccggtcacgg atacaacctc cgctccggtc 22020
aagcctcctc gtagatggga tcaagtgaag ggtgacggta agcacgagcg gcagggctac 22080
cgatcatgga gggcccacaa agccgcgatc atcgcctgct tgcaagactg cggggggaac 22140
atcgctttcg cccgccgcta cctgctcttc caccgcgggg tgaacatccc ccgcaacgtg 22200
ttgcattact accgtcacct tcacagctaa gaaaaagcaa gtcaaaggag tcgccggagg 22260
aggaggagga ggcctgagga tcgcggcgaa cgagcccttg accaccaggg agctgaggaa 22320
ccggatcttc cccactcttt atgccatttt tcagcagagt cgaggtcagc agcaagagct 22380
caaagtaaaa aaccggtctc tgcgctcgct cacccgcagt tgcttgtacc acaaaaacga 22440
agatcagctg cagcgcactc tcgaagacgc cgaggctctg ttccacaagt actgcgcgct 22500
cactcttaaa gactaaggcg cgcccacccg gaaaaaaggc gggaattacc tcatcgccac 22560
catgagcaag gagattccca ccccttacat gtggagctat cagccccaaa tgggcctggc 22620
cgcgggcgcc tcccaggact actccacccg catgaactgg ctcagtgccg gcccctcgat 22680
gatctcacgg gtcaacgggg tccgcagtca tcgaaaccag atattgttgg agcaggcggc 22740
ggtcacctcc acgcccaggg caaagctcaa cccgcgtaat tggccctcca ccctggtgta 22800
tcaggaaatc cccgggccga ctaccgtact acttccgcgt gacgcactgg ccgaagtccg 22860
catgactaac tcaggtgtcc agctggccgg cggcgcttcc cggtgcccgc tccgcccaca 22920
atcgggtata aaaaccctgg tgatccgagg cagaggcaca cagctcaacg acgagttggt 22980
gagctcttcg atcggtctgc gaccggacgg agtgttccaa ctagccggag ccgggagatc 23040
ctccttcact cccaaccagg cctacctgac cttgcagagc agctcttcgg agcctcgctc 23100
cggaggcatc ggaaccctcc agtttgtgga ggagtttgtg ccctcggtct acttcaaccc 23160
cttctcggga tcgccaggcc tctacccgga cgagttcata ccgaacttcg acgcagtgag 23220
agaagcggtg gacggctacg actgaatgtc ccatggtgac tcggctgagc tcgctcggtt 23280
gaggcatctg gaccactgcc gccgcctgcg ctgcttcgcc cgggagagct gcggactcat 23340
ctactttgag tttcccgagg agcaccccaa cggccctgca cacggagtgc ggatcaccgt 23400
agagggcacc accgagtctc acctggtcag gttcttcacc cagcaaccct tcctggtcga 23460
gcgggaccgg ggcgccacca cctacaccgt ctactgcatc tgtccaaccc cgaagttgca 23520
tgagaatttt tgttgtactc tttgtggtga gtttaataaa agctaaactc ttgcaatact 23580
ctggaccttg tcgtcgtcaa ctcaacgaga ccgtctacct caccaaccag actgaggtaa 23640
aactcacctg cagaccacac aagacctata tcatctggtt cttcgagaac acctcatttg 23700
cagtctccaa cactcactgc actagtccat gaactgatgt tgattaaaag cccaaaaacc 23760
aatcagcccc ttcccccatt tccccatccc ccaattactc ataaaaaata aatcattgga 23820
attaatcatt caataaagat cacttacttg aaatctgaaa gtatgtctct ggtgtagttg 23880
ttcagcagca cctcggtacc ctcctcccag ctctggtact ccagtccccg gcgggcggcg 23940
aacttcctcc acaccttgaa agggatgtca aattcctggt ccacaatttt cattgtcttc 24000
cctctcagat ggcaaagagg ctccgggtgg aagatgactt caaccccgtc tacccctatg 24060
gctacgcgcg gaatcagaat atccccttcc tcactccccc ctttgtctcc tccgatggat 24120
tcaaaaactt cccccctggg gtcctgtcac ttaaactggc tgatccaatc accatcaaca 24180
atggggatgt ctcacttaag gtgggagggg gacttgctgt agagcaacag actggtaacc 24240
taagcgtaaa ccctgatgca cccttgcaag ttgcaagtga taagctacag cttgctctgg 24300
ctcctccatt cgaggtcaga gatggaaagc ttgctttaaa ggcaggtaat ggattaaaag 24360
tactagataa ttccattact ggattgactg gattattgaa tacacttgtg gtattaactg 24420
gaaggggaat aggaacggag gaattaaaaa atgacgatgg tgtaacaaac aaaggagtcg 24480
gcttgcgtgt aagacttgga gatgacggcg ggctgacatt tgataaaaag ggtgatttag 24540
tagcctggaa taaaaaagat gacaggcgca ccctgtggac aacccctgac acatctccaa 24600
attgcaaaat gagtacagaa aaggattcta aacttacgtt gacacttaca aagtgtggaa 24660
gtcaggttct gggaaatgta tctttacttg cagttacagg tgaatatcat caaatgactg 24720
ctactacaaa gaaggatgta aaaatatctt tactatttga tgagaatgga attctattac 24780
catcttcgtc ccttagcaaa gattattgga attacagaag tgatgattct attgtatctc 24840
aaaaatataa taatgcagtt ccattcatgc caaacctgac agcttatcca aaaccaagcg 24900
ctcaaaatgc aaaaaactat tcaagaacta aaatcataag taatgtctac ttaggtgctc 24960
ttacctacca acctgtaatt atcactattg catttaatca ggaaactgaa aatggatgtg 25020
cttattctat aacatttacc ttcacttggc aaaaagacta ttctgcccaa cagtttgatg 25080
ttacatcttt taccttctca tatcttaccc aagagaacaa agacaaagac taataaaatg 25140
ttttgaactg aatttatgaa tctttattta tttttacacc agcacgggta gtcagtttcc 25200
caccaccagc ccatttcaca gtgtaaacag tcctttctcc ccggctggcc ttaaaaagca 25260
tcatatcatg ggtaacagac atattcttag gtgttatatt ccacacggtt tcctgtcgag 25320
ccaaacgctc atcagtgata ttaataaact ccccgggcag ctcacttaag ttcatgtcgc 25380
tgtccagctg ctgagccaca ggctgctgtc caacttgcgg ttgcttaacg ggcggcgaag 25440
gagaagtcca cgcctacatg ggggtagagt cataatcgtg catcaggata gggcggtggt 25500
gctgcagcag cgcgcgaata aactgctgcc gccgccgctc cgtcctgcag gaatacaaca 25560
tggcagtggt ctcctcagcg atgattcgca ccgcccgcag cataaggcgc cttgtcctcc 25620
gggcacagca gcgcaccctg atctcactta aatcagcaca gtaactgcag cacagcacca 25680
caatattgtt caaaatccca cagtgcaagg cgctgtatcc aaagctcatg gcggggacca 25740
cagaacccac gtggccatca taccacaagc gcaggtagat taagtggcga cccctcataa 25800
acacgctgga cataaacatt acctcttttg gcatgttgta attcaccacc tcccggtacc 25860
atataaacct ctgattaaac atggcgccat ccaccaccat cctaaaccag ctggccaaaa 25920
cctgcccgcc ggctatacac tgcagggaac cgggactgga acaatgacag tggagagccc 25980
aggactcgta accatggatc atcatgctcg tcatgatatc aatgttggca caacacaggc 26040
acacgtgcat acacttcctc aggattacaa gctcctcccg cgttagaacc atatcccagg 26100
gaacaaccca ttcctgaatc agcgtaaatc ccacactgca gggaagacct cgcacgtaac 26160
tcacgttgtg cattgtcaaa gtgttacatt cgggcagcag cggatgatcc tccagtatgg 26220
tagcgcgggt ttctgtctca aaaggaggta gacgatccct actgtacgga gtgcgccgag 26280
acaaccgaga tcgtgttggt cgtagtgtca tgccaaatgg aacgccggac gtagtcattg 26340
aaatggattc tcttgcgtac cttgtcgtac ttctgccagc agaaagtggc tcgggaacag 26400
cagatacctt tcctcctgct gtccttccgc tgctgacgct cagtcatcca actgaagtac 26460
agccattccc gcaggttctc cagcagctcc tgtgcatctg atgaaacaaa agtcccgtcg 26520
atgcggattc cccttaaaac atcagccagg acattgtagg ccatcccaat ccagttaatg 26580
catcctgatc tatcatgaag aggaggtggg ggaagaactg gaagaaccat ttttattcca 26640
agcggtctcg aaggacgata aagtgcaagt cacgcaggtg acagcgttcc ccgccgctgt 26700
gctggtggaa acagacagcc aggtcaaaac ccactctatt ttcaaggtgc tcgactgtgg 26760
cttcgagcag tggctctacg cgtacatcca gcataagaat cacattaaag gctggacctc 26820
catcgatttc atcaatcatc aggttacact cattcaccat ccccaggtaa ttctcatttt 26880
tccagccttg gattatttct acaaattgtt ggtgtaagtc cactccgcac atgtggaaaa 26940
gttcccacag cgccccctcc actttcataa tcaggcagac cttcatatta gaaacagatc 27000
ctgctgctcc accacctgca gcgtgttcaa aacaacaaga ttcaatgagg ttctgccctc 27060
tgccctcagc tcacgtctca gcgtcagctg caaaaagtca ctcaagtcct cagccactac 27120
agctgacaat tcagagccag ggctaagcgt gggactggca agcgtgagtg agtactttaa 27180
tgctccaaag ctagcaccca aaaactgcat gctggaataa gctctctttg tgtcaccggt 27240
gatgccttcc aataggtgag tgataaagcg aggtagtttt tctttaatca tttgagtaat 27300
agaaaagtcc tctaaataag tcactaggac cccaggaacc acaatgtggt agctgacagc 27360
gtgtcgctca agcatggtta gtagagatga gagtctgaaa aacagaaagc atgcactaaa 27420
ccagagttgc cagtctcact gaaggaaaaa tcactctctc cagcagcaaa gtgcccactg 27480
ggtggccctc tcggacatac aaaaatcgat ccgtgtggtt aaagagcagc acagttagct 27540
cctgtcttct cccagcaaag atcacatcgg actgggttag tatgcccctg gaatggtagt 27600
cattcaaggc cataaatctg ccttggtagc cattaggaat cagcacgctc actctcaagt 27660
gaaccaaaac caccccatgc ggaggaatgt ggaaagattc tgggcaaaaa aaggtatatc 27720
tattgctagt cccttcctgg acgggagcaa tccctccagg gctatctatg aaagcataca 27780
gagattcagc catagctcag cccgcttacc agtagacaga gagcacagca gtacaagcgc 27840
caacagcagc gactgactac ccactgaccc agctccctat ttaaaggcac cttacactga 27900
cgtaatgacc aaaggtctaa aaaccccgcc aaaaaaacac acacgccctg ggtgtttttc 27960
gcgaaaacac ttccgcgttc tcacttcctc gtatcgattt cgtgactcaa cttccgggtt 28020
cccacgttac gtcacttctg cccttacatg taactcagcc gtagggcgcc atcttgccca 28080
cgtccaaaat ggcttccatg tccggccacg cctccgcggc gaccgttagc cgtgcgtcgt 28140
gacgtcattt gcatcaccgt ttctcgtcca atcagcgttg gctccgcccc aaaaccgtta 28200
aaattcaaaa gctcatttgc atattaactt ttgtttactt tgtggggtat attattgatg 28260
atg 28263
<210> 6
<211> 28305
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr13
<400> 6
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg aaggtaggtt 480
tgagtagtgg gcgtggctaa ggtgactata aaggcgggtg tcttacgagg gtctttttgc 540
ttttctgcag acatcatgaa cgggactggc ggggccttcg aaggggggct ttttagccct 600
tatttgacaa cccgcctgcc gggatgggcc ggagttcgtc agaatgtgat gggatcgacg 660
gtggatgggc gcccagtgct tccagcaaat tcctcgacca tgacctacgc gaccgtgggg 720
aactcgtcgc tcgacagcac cgccgcagcc gcggcagccg cagccgccat gacagcgacg 780
agactggcct cgagctacat gcccagcagc ggtagtagcc cctctgtgcc cagttccatc 840
atcgccgagg agaaactgct ggccctgctg gccgagctgg aagccctgag ccgccagctg 900
gccgccctga cccagcaggt gtccgagctc cgcgaacagc agcagcagca aaataaatga 960
ttcaataaac acagattctg attcaaacag caaagcatct ttattattta ttttttcgcg 1020
cgcggtaggc cctggtccac ctctcccgat cattgagagt gcggtggatt ttttccagga 1080
cccggtagag gtgggattgg atgttgaggt acatgggcat gagcccgtcc cgtgggtgga 1140
ggtagcacca ctgcatggcc tcgtgctctg gggtcgtgtt gtagatgatc cagtcatagc 1200
aggggcgctg ggcgtggtgc tggatgatgt ccttgaggag gagactgatg gccacgggga 1260
gccccttggt gtaggtgttg gcaaaacggt tgagctggga gggatgcatg cggggggaga 1320
tgatgtgcag tttggcctgg atcttgaggt tggcgatgtt gccacccaga tcccgccggg 1380
ggttcatgtt gtgcaggacc accagaacgg tgtagcccgt gcacttgggg aacttgtcat 1440
gcaacttgga agggaatgcg tggaagaatt tggagacgcc cttgtgcccg cccaggtttt 1500
ccatgcactc atccatgatg atggcaatgg gcccgtgggc tgcggctttg gcaaagacgt 1560
ttctggggtc agagacatcg taattatgct cctgggtgag atcatcataa gacattttaa 1620
tgaatttggg gcggagggtg ccagattggg ggacgatggt tccctcgggc cccggggcga 1680
agttcccctc gcagatctgc atctcccagg ctttcatctc ggaggggggg atcatgtcca 1740
cctgcggggc gatgaaaaaa acggtttccg gggcgggggt gatgagctgc gaggagagca 1800
ggtttctcaa cagctgggac ttgccgcacc cggtcgggcc gtagatgacc ccgatgacgg 1860
gttgcaggtg gtagttcaag gacatgcagc tgccgtcgtc ccggaggagg ggggccacct 1920
cgttgagctt gtctctgact tggaggtttt cccggacgag ctcgccgagg aggcggtccc 1980
cgcccagcga gagaagctct tgcagggaag caaagttttt caggggcttg agcccgtcgg 2040
ccatgggcat cttggcgagg gtctgcgaga ggagctccag gcggtcccag agctcggtga 2100
cgtgctctac ggcatctcga tccagcagac ttcctcgttt cgggggttgg gacgactgcg 2160
actgtagggc acgagacgat gggcgtccag cgcggccagc gtcatgtcct tccagggtct 2220
cagggtccgc gtgagggtgg tctccgtcac ggtgaagggg tgggccgcgg gctgggcgct 2280
tgcaagggtg cgcttgagac tcatcctgct ggtgctgaaa cgggcacggt cttcgccctg 2340
cgcgtcggcg agatagcagt tgaccatgag ctcgtagttg agggcctcgg cggcgtggcc 2400
cttggcgcgg agcttgccct tggaagagcg cccgcaggcg ggacagagga gggattgcag 2460
ggcgtagagc ttgggcgcga gaaagacgga ctcgggggcg aaggcgtccg ctccgcagtg 2520
ggcgcagacg gtctcgcact cgactagcca ggtgagctcg ggctgctcgg ggtcaaaaac 2580
cagttttccc ccgttctttt tgatgcgctt cttacctcgc gtctccatga gtctgtgtcc 2640
gcgctcggtg acaaacaggc tgtctgtgtc cccgtagacg gacttgatgg gcctgtcctg 2700
caggggcgtc ccgcggtcct cctcgtagag aaactcagac cactctgaga cgaaggcgcg 2760
cgtccacgcc aagacaaagg aggccacgtg cgaggggtag cggtcgttgt ccaccagggg 2820
gtccaccttt tccacggtat gcaggcacat gtccccctcc tccgcatcca agaaggtgat 2880
tggcttgtag gtgtaggcca cgtgacctgg ggttcccgac gggggggtat aaaagggggc 2940
gggtctgtgc tcgtcctcac tctcttccgc gtcgctgtcc acgagcgcca gctgttgggg 3000
taggtattcc ctctcaagag cgggcatgac ctcggcactc aggttgtcag tttctagaaa 3060
cgaggaggat ttgatgtggg cctgccctgc cgcgatgctt tttaggagac tttcatccat 3120
ctggtcagaa aagactattt ttttattgtc aagcttggtg gcgaaggagc catagagggc 3180
gtttgagaga agcttggcga tggatctcat ggtctgattt ttgtcacggt cggcgcgctc 3240
cttggccgcg atgttgagct ggacatattc gcgcgcgaca cacttccatt cggggaagac 3300
ggtggtgcgc tcgtcgggca cgatcctgac gcgccagccg cggttatgca gggtgaccag 3360
gtccacgctg gtggccacct cgccgcgcag gggctcgttg gtccagcaga gtctgccgcc 3420
cttgcgcgag cagaacgggg gcagcacatc aagcagatgc tcgtcagggg ggtccgcatc 3480
gatggtgaag atgcccggac agagttcctt gtcaaaataa tcgatttttg aggatgcatc 3540
gtccaaggcc atctgccact cgcgggcggc cagcgctcgc tcgtaggggt tgaggggcgg 3600
accccaaggc atgggatgcg tgagggcgga ggcgtacatg ccgcagatgt catagacata 3660
gatgggctcc gagaggatgc cgatgtaggt gggatagcag cgccccccgc ggatgcttgc 3720
gcgcacgtag tcatacaact cgtgcgaggg ggccaagaag gcggggccga gattggtgcg 3780
ctggggctgc tcggcgcgga agacgatctg gcgaaagatg gcgtgcgagt tggaggagat 3840
ggtgggccgt tggaagatgt taaagtgggc gtgaggcagg cggaccgagt cgcggatgaa 3900
gtgcgcgtag gagtcttgca gcttggcgac gagctcggcg gtgacgagga cgtccatggc 3960
gcagtagtcc agcgtttcgc ggatgatgtc ataactcgcc tctcctttct tctcccacag 4020
ctcgcggttg agggcgtatt cctcgtcatc cttccagtac tcccggagcg ggaatcctcg 4080
atcgtccgca cggtaagagc ccagcatgta gaaatggttc acggccttgt agggacagca 4140
gcccttctcc acggggaggg cgtaagcttg agcggccttg cggagcgagg tgtgcgtcag 4200
ggcaaaggtg tccctgacca tgactttcaa gaactggtac ttgaagtccg agtcgtcgca 4260
gccgccgtgc tcccagagct cgaaatcggt gcgcttcttc gagagggggt taggcagagc 4320
gaaagtgacg tcattgaaga gaatcttgcc tgcccgcggc atgaaattgc gggtgatgcg 4380
gaaagggccc gggacggagg ctcggttgtt gatgacctgg gcggcgagga cgatctcgtc 4440
aaagccgttg atgttgtgcc cgacgatgta gagttccatg aatcgcgggc ggcctttgat 4500
gtgcggcagc tttttgagct cctcgtaggt gaggtcctcg gggcattgca ggccgtgctg 4560
ctcgagcgcc cactcctgga gatgtgggtt ggcttgcatg aaggaagccc agagctcgcg 4620
ggccatgagg gtctggagct cgtcgcgaaa gaggcggaac tgctggccca cggccatctt 4680
ttctggggtg acgcagtaga aggtgagggg gtcccgctcc cagcgatccc agcgtaaacg 4740
cacggcgaga tcgcgagcga gggcgaccag ctctgggtcc ccggagaatt tcatgaccag 4800
catgaagggg acgagctgct tgccgaagga ccccatccag gtgtaggttt ctacatcgta 4860
ggtgacaaag agccgctccg tgcgaggatg agagccgatt gggaagaact ggatttcctg 4920
ccaccagttg gacgagtggc tgttgatgtg atgaaagtag aaatcccgcc ggcgaaccga 4980
gcactcgtgc tgatgcttgt aaaagcgtcc gcagtactcg cagcgctgca cgggctgtac 5040
ctcatccacg agatacacag cgcgtccctt gaggaggaac ttcaggagtg gcggccctgg 5100
ctggtggttt tcatgttcgc ctgcgtggga ctcaccctgg ggctcctcga ggacggagag 5160
gctgacgagc ccgcgcggga gccaggtcca gatctcggcg cggcgggggc ggagagcgaa 5220
gacgagggcg cgcagttggg agctgtccat ggtgtcgcgg agatccaggt ccgggggcag 5280
ggttctgagg ttgacctcgt agaggcgggt gagggcgtgc ttgagatgca gatggtactt 5340
gatttctacg ggtgagttgg tggtcgtgtc cacgcattgc atgagcccgt agctgcgcgg 5400
ggccacgacc gtgccgcggt gcgcttttag aagcggtgtc gcggacgcgc tcccggcggc 5460
agcggcggtt ccggccccgc gggcaggggc ggcagaggca cgtcggcgtg gcgctcgggc 5520
aggtcccggt gctgcgccct gagagcgctg gcgtgcgcga cgacgcggcg gttgacatcc 5580
tggatctgcc gcctctgcgt gaagaccacg ggccccgtga ctttgaacct gaaagacagt 5640
tcaacagaat caatctctgc gtcattgacg gcggcctgac gcaggatctc ttgcacgtcg 5700
cccgagttgt cctggtaggc gatctcggac atgaactgtt cgatctcctc ctcctggaga 5760
tcgccgcggc ccgcgcgctc cacggtggcg gcgaggtcat tggagatgcg acccatgagc 5820
tgcgagaagg cgcccaggcc gctctcgttc cagacgcggc tgtagaccac gtccccgtcg 5880
gcgtcgcgcg cgcgcatgac cacctgcgcg aggttgagct ccacgtgccg cgcaaagacg 5940
gcgtagttgc gcaggcgctg gaagaggtag ttgagggtgg tggcgatgtg ctcggtgacg 6000
aagaagtaca tgatccagcg gcgcaggggc atctcgctga tgtcgccgat ggcttccagc 6060
ctttccatgg cctcgtagaa gtccacggcg aagttgaaaa actgggcgtt gcgggccgag 6120
accgtgagct cgtcttccag gagccggatg agttcggcga tggtggcgcg cacctcgcgc 6180
tcgaaatccc cgggggcctc ctcctcttcc tcttcttcca tgacgacctc ttcttctatt 6240
tcttcctctg ggggcggtgg tggtggcggg ggccgacgac gacggcgacg caccgggaga 6300
cggtcgacga agcgctcgat catctccccg cggcggcgac gcatggtttc ggtgacggcg 6360
cgaccccgtt cgcgaggacg cagcgtgaag acgccgccgg tcatctcccg gtaatggggc 6420
gggtccccat tgggcagcga tagggcgctg acgatgcatc ttatcaattg cggtgtaggg 6480
gacgtgagcg cgtcgagatc gaccggatcg gagaatcttt cgaggaaagc gtctagccaa 6540
tcgcagtcgc aaggtaagct caaacacgta gcagccctgc ggacgctgtt agaattgcgg 6600
ttgctgatga tgtaattgaa gtaggcgttt ttgaggcggc ggatggtggc gaggaggacc 6660
aggtccttgg gtccagcttg ctggatgcgg agccgctcgg ccatgcccca ggcctggccc 6720
tgacaccggc tcaggttctt gtagtagtca tgcatgagcc tctcaatgtc atcactggct 6780
gaggcggagt cttccatgcg ggtgaccccg acgcccctga gcggctgcac gagcgccagg 6840
tcggcgacga cgcgctcggc gaggatggcc tgttgcacgc gggtgagggt gtcctggaag 6900
tcgtccatgt cgacgaagcg gtgataggcc ccggtgttga tggtgtaggt gcagttggcc 6960
atgagcgacc agttgacggt ctgcaggcct ggctgcacga cctcggagta cctgagccgc 7020
gagaaggcgc gcgagtcgaa gacgtagtcg ttgcaggtgc gcacgaggta ctggtatccg 7080
actaggaagt gcggcggcgg ctggcggtag agcggccagc gctgggtggc cggcgcgccc 7140
ggggccaggt cctcgagcat gaggcggtgg tagccgtaga ggtagcggga catccaggtg 7200
atgccggcgg cggtggtgga ggcgcgcggg aactcgcgga cgcggttcca gatgttgcgc 7260
agcggcagga aatagtccat ggtcggcacg gtctggccgg tgagacgcgc gcagtcattg 7320
acgctctaga ggcaaaaacg aaagcggttg agcgggctct tcctccgtag cctggcggaa 7380
cgcaaacggg ttaggccgcg tgtgtacccc ggttcgagtc ccctcgaatc aggctggagc 7440
cgcgactaac gtggtattgg cactcccgtc tcgacccgag cccgatagcc gccaggatac 7500
ggcggagagc cctttttgcc ggccgagtgg ggtcgctaga cttgaaagcg accgaaaacc 7560
ctgccgggta gtggctcgcg cccgtagtct ggagaagcat cgccagggtt gagtcgcggc 7620
agaacccggt tcgaggacgg ccgcggcgag cgggacttgg tcaccccgcc gatataaaga 7680
cccacagcca gccgacttct ccagttacgg gagcgagccc ccttttttct ttttgccaga 7740
tgcatcccgt cctgcgccaa atgcgtccca cccccccggc gaccaccgcg accgcggccg 7800
tagcaggcgc cggcgctagc cagccaccac agacagagat ggacttggaa gagggcgaag 7860
ggctggcaag actgggggcg ccgtccccgg agcgacatcc ccgcgtgcag ctgcagaagg 7920
acgtgcgccc ggcgtacgtg cctacgcaga acctgttcag ggaccgcagc ggggaggagc 7980
ccgaggagat gcgcgactgc cggtttcggg cgggcaggga gctgcgcgag ggcctggacc 8040
gccagcgcgt gctgcgcgac gaggatttcg agccgaacga gcagacgggg atcagccccg 8100
cacgcgcgca cgtggcggca gccaacctgg tgacggccta cgagcagacg gtgaagcagg 8160
agcgcaactt ccaaaagagt ttcaacaacc acgtgcgcac cctgatcgcg cgcgaggagg 8220
tggccctggg cctgatgcac ctgtgggacc tggcggaggc catcgtgcag aacccggaca 8280
gcaagcctct gacggcgcag ctgttcctgg tggtgcagca cagcagggac aacgaggcgt 8340
tcagggaggc gctgctgaac atcgccgagc ccgagggtcg ctggctgctg gagctgatta 8400
acatcttgca gagcatcgta gtgcaggagc gcagcctgag cctggccgag aaggtggcgg 8460
cgatcaacta ctcggtgctg agcctgggca agttttacgc gcgcaagatt tacaagacgc 8520
cgtacgtgcc catagacaag gaggtgaaga tagacagctt ttacatgcgc atggcgctca 8580
aggtgctgac gctgagcgac gacctgggcg tgtaccgcaa cgaccgcatc cacaaggccg 8640
tgagcacgag ccggcggcgc gagctgagcg accgcgagct gatgctgagt ctgcgccggg 8700
cgctggtagg gggcgccgcc ggcggcgagg agtcctactt cgacatgggt gcggacctgc 8760
attggcagcc gagccggcgc gccttggagg ccgcctacgg ttcagaggac ttggatgagg 8820
aagaggaaga ggaggaggat gcacccgctg cggggtactg acgcctccgt gatgtgtttt 8880
tagatgtccc agcaagcccc ggaccccgcc ataagggcgg cgctgcaaag ccagccgtcc 8940
ggtctagcat cggacgactg ggaggccgcg atgcaacgca tcatggccct gacgacccgc 9000
aaccccgagt cctttagaca acagccgcag gccaacagac tctcggccat tctggaggcg 9060
gtggtcccct ctcggaccaa ccccacgcac gagaaggtgc tggcgatcgt gaacgcgctg 9120
gcggagaaca aggccatccg tcccgacgag gccgggctgg tgtacaacgc cctgctggag 9180
cgcgtgggcc gctacaacag cacgaacgtg cagtccaacc tggatcggct ggtgacggac 9240
gtgcgcgagg ccgtggcgca gcgcgagcgg ttcaagaacg agggcctggg ctcgctggtg 9300
gcgctgaacg ccttcctggc gacgcagccg gcgaacgtgc cgcgcgggca ggacgattac 9360
accaacttta tcagcgcgct gcggctgatg gtgaccgagg tgccccagag cgaggtgtac 9420
cagtctggcc cggactactt tttccagacg agccggcagg gcttgcagac ggtgaacctg 9480
agccaggctt tcaagaatct gcgcgggctg tggggcgtgc aggcgcccgt gggcgaccgg 9540
tcaacggtga gcagcttgct gacgcccaac tcgcggctgc tgctgctgct gatcgcgccc 9600
ttcaccgaca gcggcagcgt gaaccgcaac tcgtacctgg gccatctgct gacgctgtac 9660
cgcgaggcca taggccaggc gcaggtggac gagcagacct tccaggagat cactagcgtg 9720
agccgcgcgc tggggcagaa cgacaccgac agtctgaggg ccaccctgaa ctttttgctg 9780
accaatagac agcagaagat cccggcgcag tacgcactgt cggccgagga ggaaaggatt 9840
ctgagatatg tgcagcagag cgtagggctg ttcctgatgc aggagggtgc cacccccagc 9900
gccgcgctgg acatgaccgc gcgcaacatg gaacctagca tgtacgccgc caaccggccg 9960
ttcatcaata agctgatgga ctacttgcac cgcgcggcgg ccatgaacac ggactacttt 10020
accaacgcca tcctgaaccc gcactggctc ccgccgccgg ggttctacac gggcgagtac 10080
gacatgcccg accccaacga cgggttcctg tgggacgacg tggacagcgc ggtgttctcg 10140
ccgacctttc aaaagcgcca ggaggcgccg ccgagcgagg gcgcggtggg gaggagcccc 10200
tttcctagct tagggagttt gcatagcttg ccgggctcgg tgaacagcgg cagggtgagc 10260
cggccgcgct tgctgggcga ggacgagtac ctgaacgact cgctgctgca gccgccgcgg 10320
gccaagaacg ccatggccaa taacgggata gagagtctgg tggacaaact gaaccgctgg 10380
aagacctacg ctcaggacca tagggacgcg cccgcgccgc ggcgacagcg ccacgaccgg 10440
cagcggggcc tggtgtggga cgacgaggac tcggccgacg atagcagcgt gttggacttg 10500
ggcgggagcg gtggggtcaa cccgttcgcg catctgcagc ccaaactggg gcgacggatg 10560
ttttgaatga aataaaactc accaaggcca tagcgtgcgt tctcttcctt gttagagatg 10620
aggcgcgcgg tggtgtcttc ctctcctcct ccctcgtacg agagcgtgat ggcgcaggcg 10680
accctggagg ttccgtttgt gcctccgcgg tatatggctc ctacggaggg cagaaacagc 10740
attcgttact cggagctggc tccgcagtac gacaccactc gcgtgtactt ggtggacaac 10800
aagtcggcgg acatcgcttc cctgaactac caaaacgacc acagcaactt cctgaccacg 10860
gtggtgcaga acaacgattt cacccccgcc gaggccagca cgcagacgat aaattttgac 10920
gagcggtcgc ggtggggcgg tgatctgaag accattctgc acactaacat gcccaatgtg 10980
aacgagtaca tgttcaccag caagtttaag gcgcgggtga tggtgtctag gaagcatcca 11040
gagggggtag ttgaaacaga tttgagtcag gataagcttg aatatgagtg gtttgagttt 11100
accctgcccg agggaaactt ttccgagacc atgaccatag acctgatgaa caacgccatc 11160
ttggaaaact acttgcaagt ggggcggcag aatggcgtgc tggagagcga tatcggagtc 11220
aagtttgaca gcagaaattt caagctgggc tgggacccgg tgaccaagct ggtgatgcca 11280
ggggtctaca cctacgaggc cttccacccg gacgtggtgc tgctgccggg ctgcggggtg 11340
gacttcaccg agagccgcct gagcaacctc ctgggcattc gcaagaagca acctttccaa 11400
gagggcttca gaatcatgta tgaggatcta gaaggtggca acatccccgc cctccttgat 11460
gtgcccaagt acttggaaag caagaagaaa gttgaagacg aaactaaaaa tgcagctgcg 11520
gccacagccg atacaaccac taggggtgat acatttgcaa ctccagcgca agagacagca 11580
gctgataaga aggtagaagt cttgcccatt gaaaaggatg agagtggtag aagttacaac 11640
ctgatccagg ggacccacga cacgctgtac cgcagttggt acctgtccta tacctacggg 11700
gaccccgaga agggggtgca gtcgtggacg ctgctcacca ccccggacgt tacctgcggc 11760
gcggagcaag tctactggtc actgccggac ctcatgcaag accccgtcac cttccgctcc 11820
acccagcaag tcagcaacta ccccgtggtc ggcgccgagc tcatgccctt ccgcgccaag 11880
agcttttaca acgacctcgc cgtctactcc cagctcatcc gcagctacac ctccctcacc 11940
cacgtcttca accgcttccc cgacaaccag atcctctgcc gcccgcccgc gcccaccatc 12000
accaccgtca gtgaaaacgt gcctgctctc acagatcacg ggacgctacc gctgcgcagc 12060
agtatccgcg gagtccagcg agtgaccgtc actgacgccc gtcgccgcac ctgtccctac 12120
gtctacaagg ccctgggcat agtcgcgccg cgcgtgcttt ccagtcgcac cttctaaaaa 12180
aatgtctatt ctcatctcgc ccagcaataa caccggctgg ggtcttacta gacccagcac 12240
catgtacgga ggagccaaga agcgctccca gcagcacccc gtccgcgtcc gcggccactt 12300
ccgcgctccc tggggcgcat acaagcgcgg gcggacttcc accgccgccg tgcgcaccac 12360
cgtcgacgac gtcatcgact cggtggtcgc cgacgcgcgc aactataccc ccgccccctc 12420
caccgtggac gcggtcatcg acagcgtggt ggccgacgcg cgcgactatg ccagacgcaa 12480
gagccggcgg cgacggatcg ccaggcgcca ccggagcacg cccgccatgc gcgccgcccg 12540
ggctctgctg cgccgcgcca gacgcacggg ccgccgggcc atgatgcgag ccgcgcgccg 12600
cgctgccact gcacccaccc ccgcaggcag gactcgcaga cgagcggccg ccgccgccgc 12660
tgcggccatc tctagcatga ccagacccag gcgcggaaac gtgtactggg tgcgcgactc 12720
cgtcacgggc gtgcgcgtgc ccgtgcgcac ccgtcctcct cgtccctgat ctaatgcttg 12780
tgtcctcccc cgcaagcgac gatgtcaaag cgcaaaatca aggaggagat gctccaggtc 12840
gtcgccccgg agatttacgg accaccccag gcggaccaga aaccccgcaa aatcaagcgg 12900
gttaaaaaaa aggatgaggt ggacgagggg gcagtagagt ttgtgcgcga gttcgctccg 12960
cggcggcgcg taaattggaa ggggcgcagg gtgcagcgcg tgttgcggcc cggcacggcg 13020
gtggtgttca cgcccggcga gcggtcctcg gtcaggagca agcgtagcta tgacgaggtg 13080
tacggcgacg acgacatcct ggaccaggcg gcggagcggg cgggcgagtt cgcctacggg 13140
aagcggtcgc gcgaagagga gctgatctcg ctgccgctgg acgaaagcaa ccccacgccg 13200
agcctgaagc ccgtgaccct gcagcaggtg ctgccccagg cggtgctgct gccgagccgc 13260
ggggtcaagc gcgagggcga gagcatgtac ccgaccatgc agatcatggt gcccaagcgc 13320
cggcgcgtgg aggacgtgct ggacaccgtg aaaatggatg tggagcccga ggtcaaggtg 13380
cgccccatca agcaggtggc gccgggcctg ggcgtgcaaa ccgtggacat tcagatcccc 13440
accgacatgg atgtcgacaa aaaaccctcg accagcatcg aggtgcaaac cgacccctgg 13500
ctcccagcct ccaccgctac cgtctccact tctaccgccg ccacggctac cgagcctccc 13560
aggaggcgaa gatggggcgc cgccagccgg ctgatgccca actacgtgtt gcatccttcc 13620
atcatcccga cgccgggcta ccgcggcacc cggtactacg ccagccgccg gcgcccagcc 13680
agcaaacgcc gccgccgcac cgccacccgc cgccgtctgg cccccgcccg cgtgcgccgc 13740
gtgaccacgc gccggggccg ctcgctcgtt ctgcccaccg tgcgctacca ccccagcatc 13800
ctttaatccg tgtgctgtga tactgttgca gagagatggc tctcacttgc cgcctgcgca 13860
tccccgtccc gaattaccga ggaagatccc gccgcaggag aggcatggca ggcagcggcc 13920
tgaaccgccg ccggcggcgg gccatgcgca ggcgcctgag tggcggcttt ctgcccgcgc 13980
tcatccccat aatcgccgcg gccattggca cgatcccggg catagcttcc gttgcgctgc 14040
aggcgtcgca gcgccgttga tgtgcgaata aagcctcttt agactctgac acacctggtc 14100
ctgtatattt ttagaatgga agacatcaat tttgcgtccc tggctccgcg gcacggcacg 14160
cggccgttca tgggcacctg gaacgagatc ggcaccagcc agctgaacgg gggcgccttc 14220
aattggagca gtgtctggag cgggcttaaa aatttcggct cgacgctccg gacctatggg 14280
aacaaggcct ggaatagtag cacggggcag ttgttgaggg aaaagctcaa agaccagaac 14340
ttccagcaga aggtggtgga cgggctggcc tcgggcatta acggggtggt ggacatcgcg 14400
aaccaggccg tgcagcgcga gataaacagc cgcctggacc cgcgaccgcc cacggtggtg 14460
gagatggaag atgcaactct tccgccgccc aagggcgaga agcggccgcg gcccgacgcg 14520
gaggagacga tcctgcaggt ggacgagccg ccctcgtacg aggaggccgt caaggccggc 14580
atgcccacca cgcgcatcat cgcgccgctg gccacgggtg taatgaaacc cgccaccctt 14640
gacctgcctc caccacccgc gcccgctcca ccgaaggcaa ctccggttgt gcaggccccc 14700
ccggtggcga ccgccgtgcg ccgcgtcccc gcccgccgcc aggcccagaa ctggcagagc 14760
acgctgcaca gtatcgtggg cctgggagtg aaaagtctga agcgccgccg atgctattga 14820
gagagaggaa agaggacact aaagggagag cttaacttgt atgtgcctta ccgccagaga 14880
acgcgcgaag atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg 14940
gcaggacgcc tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac 15000
gtacttcagc ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac 15060
cacggaccgg tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac 15120
gtactcgtac aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc 15180
cagcacttac tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc 15240
gggcacggcc tacaacagcc tggctcccaa gggtgccccc aattccagcc agtgggagca 15300
agcaaaacca ggcaatgggg gaactatgga aacacacaca tatggtgtgg ccccaatggg 15360
cggagagaat attacaaaag atggtcttca aattggaact gatgctacag cggatcagaa 15420
taaaccaatt tatgctgaca aaactttcca gccagaacct caagtaggag aagaaaattg 15480
gcaagaaact gaaagctttt atggtggtag ggctcttaaa aaagacacta aaatgaaacc 15540
atgctatgga tcttttgcta gacctactaa tgagaaagga ggtcaggcaa agttcaaacc 15600
agttaatgaa ggagaacaac ctaaagatct ggatatagat ctggctttct ttgatactcc 15660
cggtggcact gtgaatggcc aagatgagta taaagcagac attgtcatgt acactgaaaa 15720
tgttaatctt gaaacaccag acactcatgt ggtttacaag ccaggcaagg aagatgcaag 15780
ttctgaaatt aacctggttc agcagtccat gccaaacaga cccaactaca ttggctttag 15840
ggacaacttt gtaggtctca tgtattacaa cagcaccgga aatatgggtg tgctggctgg 15900
tcaggcttct cagttgaacg ctgtggtcga cttgcaagac agaaacaccg agttatctta 15960
ccagctattg ctagattctc tgggtgacag aaccagatac tttagcatgt ggaactctgc 16020
ggtggacagt tacgatccag atgtcaggat cattgaaaat cacggtgtgg aagatgaact 16080
tccaaactat tgcttcccat tggatggatc tggcactaac gccgcctatc aaggtgtaaa 16140
agtaaaaaat ggtgaagatg gtgatcttga gagcgagtgg gaaaatgatg atactgtggc 16200
agctcgaaat caaatatgca aaggcaatat tttcgccatg gagatcaacc tgcaggccaa 16260
cctgtggaag agttttctgt actcgaacgt ggccctgtac ctgcccgact cctacaagta 16320
cacgccggcc aacgtcaagc tgcccgccaa caccaacacc tacgagtaca tgaacggccg 16380
cgtggtagcc ccctcgctgg tggacgccta catcaacatc ggcgcccgct ggtcgttgga 16440
tcccatggac aacgtcaacc ccttcaacca ccaccgcaat gcgggcctgc gctaccgctc 16500
catgctgctg ggcaacggcc gctacgtgcc cttccacatc caagtgcccc aaaagttctt 16560
tgccatcaag aacctgctcc tgctcccggg ctcctacacc tacgagtgga acttccgcaa 16620
ggacgtcaac atgatcctgc agagttccct cggcaacgac ctgcgcgtcg acggcgcctc 16680
cgtccgcttc gacagcgtca acctatacgc cactttcttc cccatggcgc acaacaccgc 16740
ttcaaccttg gaagccatgc tgcgcaacga caccaacgac cagtccttca acgactacct 16800
ctcggccgcc aacatgctct accccatccc ggccaaggcc accaacgtgc ccatctccat 16860
cccatcgcgc aactgggccg ccttccgcgg ctggagtttc acccggctca agaccaagga 16920
aactccttcc ctcggctcgg gtttcgaccc ctactttgtc tactcgggct ccatccccta 16980
cctcgacggg accttctacc tcaaccacac cttcaagaag gtctccatca tgttcgactc 17040
ctcggtcagc tggcccggca acgaccggct gctcacgccg aacgagttcg agatcaagcg 17100
cagcgtcgac ggggagggct acaacgtggc ccaatgcaac atgaccaagg actggttcct 17160
cgtccagatg ctctcccact acaacatcgg ctaccagggc ttccacgtgc ccgagggcta 17220
caaggaccgc atgtactcct tcttccgcaa cttccagccc atgagcaggc aggtggtcga 17280
tgagatcaac tacaaggact acaaggccgt caccctgccc ttccagcaca ataactcggg 17340
cttcaccggc tacctcgcac ccaccatgcg ccaggggcag ccctaccccg ccaacttccc 17400
ctacccgctc atcggtcaga cagccgtgcc ctccgtcacc cagaaaaagt tcctctgcga 17460
cagggtcatg tggcgcatcc ccttctccag caacttcatg tccatgggcg ccctcaccga 17520
cctgggtcag aacatgctct acgccaactc ggcccacgcg ctcgacatga ccttcgaggt 17580
ggaccccatg gatgagccca ccctcctcta tcttctcttc gaagttttcg acgtggtcag 17640
agtacaccag ccgcaccgcg gcgtcatcga ggccgtctac ctgcgcacgc ccttctccgc 17700
cggcaacgcc accacctaag catgagcggc tccagcgaac gagagctcgc ggccatcgtg 17760
cgcgacctgg gctgcgggcc ctactttttg ggcacccacg acaagcgctt cccgggcttt 17820
ctcgccggcg acaagctggc ctgcgccatc gtcaacacgg ccggccgcga gaccggaggc 17880
gtgcactggc tcgccttcgg ctggaacccg cgctcgcgca cctgctacat gttcgacccc 17940
tttgggttct cggaccgccg gctcaagcag atttacagct tcgagtacga ggccatgctg 18000
cgccgcagcg ccctggcctc ctcgcccgac cgctgtctca gcctcgagca gtccactcag 18060
accgtgcagg ggcccgactc cgccgcctgc ggactcttct gttgcatgtt cttgcatgcc 18120
ttcgtgcact ggcccgaccg acccatggac ggaaacccca ccatgaactt gctgacgggg 18180
gtgcccaacg gcatgctaca atcgccacag gtgctgccca ccctcaggcg caaccaggag 18240
gaactctacc gcttcctcgc gcgccactcc ccttactttc gctcccaccg cgccgccatc 18300
gaacacgcca ccgcttttga caaaatgaaa caactgcgtg tatctcaata aacagcactt 18360
ttattttaca tgcactggag tatatgcaag ttatttaaaa gtcgaagggg ttctcgcgct 18420
cgtcgttgtg cgccgcgctg gggagggcca cgttgcggta ctggtacttg ggctgccact 18480
tgaactcggg gatcaccagt ttgggcactg gggtctcggg gaaggtctcg ctccacatgc 18540
gccggctcat ctgcagggcg cccagcatgt ccggggcgga gatcttgaaa tcgcagttgg 18600
ggccggtgct ctgcgcgcgc gagttgcggt acacggggtt gcagcactgg aacaccatca 18660
gactggggta cttcacacta gccagcacgc tcttgtcgct gatctgatcc ttgtccagat 18720
cctcggcgtt gctcaggccg aacggggtca tcttgcacag ctggcgtccc aggaagggca 18780
cgctctgagg cttgtggtta cactcgcagt gcacgggcat cagcatcatc cccgcgccgc 18840
gctgcatatt cgggtagagg gccttgacaa aggccgcgat ctgcttgaaa gcttgctggg 18900
ccttggcccc ctcgctgaaa aacaggccgc agctcttccc gctgaactgg ttattcccac 18960
acccggcatc ctgcacgcag cagcgcgcgt catggctggt cagttgcacc acgctccgtc 19020
cccagcggtt ctgggtcacc ttagccttgc tgggctgctc cttcaacgcg cgctgcccgt 19080
tctcgctggt cacatccatc tccaccacgt ggtccttgtg gatcatcatc gtcccgtgca 19140
gacacttgag ctggccttcc acctcggtgc agccgtgatc ccacagggcg caaccggtgc 19200
actcccagtt cttgtgcgca atcccgctgt ggctgaagat gtaaccttgc aacatgcggc 19260
ccatgatggt gctaaatgct ttctgggtgg tgaaggtcag ttgcatcccg cgggcctcct 19320
cgttcatcca ggtctggcac atcttctgga agatctcggt ctgctcgggc atgagcttgt 19380
aagcatcgcg caggccgctg tcgacgcggt agcgttccat cagcacgttc atggtatcca 19440
tgcccttctc ccaggacgag accagaggca gactcagagg gttgcgtacg ttcaggacac 19500
cgggggtcgc gggctcgacg atgcgttttc cgtccttgcc ttccttcaat agaaccggcg 19560
gctggctgaa tcccactccc acgatcacgg catcttcctg gggcatctct tcgtcggggt 19620
ctaccttggt cacatgcttg gtctttctgg cttgcttctt ttttggaggg ctgtccacgg 19680
ggagcacgtc ctcctcggaa gacccggagc ccacccgctg atactttcgg cgcttggtgg 19740
gcagaggagg tggcggcgag gggctcctct cctgctccgg cggatagcgc gccgacccgt 19800
ggccccgggg cggagtggcc tctcggccca tgaaccggcg cacgtcctga ctgccgccgg 19860
ccattgtttc ctaggggaag atggaggagc agccgcgtaa gcaggagcag gaggaggact 19920
taaccaccca cgagcaaccc aaaatcgagc aggacctggg cttcgaagag ccggctcgtc 19980
tagaaccccc acaggatgaa caggagcacg agcaagacgc aggccaggag gagaccgacg 20040
ctgggctcga gcatggctac ctgggaggag aggaggatgt gctgctgaaa cacctgcagc 20100
gccagtccct catcctccgg gacgccctgg ccgaccggag cgaaaccccc ctcagcgtcg 20160
aggagctgtg tcgggcctac gagctcaacc tcttctcgcc gcgcgtaccc cccaaacgcc 20220
agcccaacgg cacctgcgag cccaacccgc gtctcaactt ctatcccgtc tttgcggtcc 20280
ccgaagccct cgccacctat cacatctttt tcaagaacca aaagatcccc gtctcctgcc 20340
gcgccaaccg caccagcgcc gacgcgctcc tcgctttggg gcccggcgcg cgcatacctg 20400
atatcgcttc cctggaagag gtgcccaaga tcttcgaagg gctcggtcgg gacgagacgc 20460
gcgcggcgaa cgctctgaaa gaaacagcag aggaagaggg tcacactagc gccctggtag 20520
agttggaagg cgacaacgcc aggctggccg tgctcaagcg cagcgtcgag cttacccact 20580
tcgcctaccc cgccgtcaac ctcccgccca aggtcatgcg tcgcatcatg gatcagctca 20640
tcatgcccca catcgaggcc ctcgatgaaa gtcaggagca gcgccccgag gacgcccggc 20700
ccgtggtcag cgacgagatg ctcgcgcgct ggctcgggac ccgcgacccc caggctttgg 20760
aacagcggcg caaactcatg ctggccgtgg tcctggtcac ccttgagctc gaatgcatgc 20820
gccgcttttt cagcgacccc gagaccctgc gcaaggtcga ggagaccctg cactacactt 20880
tcaggcacgg tttcgtcagg caggcctgca agatctccaa cgtggagctg accaacctgg 20940
tctcctgcct ggggatcctg cacgagaacc gcctgggcca gaccgtgctc cactctaccc 21000
tgaagggcga ggcgcggcgg gactatgtcc gcgactgcgt ctttctcttt ctctgccaca 21060
catggcaagc ggccatgggc gtgtggcagc agtgtctcga ggacgagaac ctaaaggagc 21120
tggacaagct tcttgctaga aaccttaaaa agctgtggac gggcttcgac gagcgcaccg 21180
tcgcctcgga cctggccgag atcgtcttcc ccgagcgcct gagacagacg ctgaaaggcg 21240
ggctgcccga cttcatgagc cagagcatgt tgcaaaacta ccgcactttc attcttgagc 21300
gatcaggcat cctgcccgcc acctgcaacg ccttcccctc cgactttgta ccgctgagct 21360
accgcgagtg tcccccgccg ctgtggagcc actgctacct cttgcagctg gccaactaca 21420
tcgcctacca ctcggacgtg atcgaggacg tgagcggcga ggggctgctc gagtgccact 21480
gtcgctgcaa cctgtgctcc ccgcatcgct ccctggtctg caacccccag ctcctgagcg 21540
agacccaggt catcggtacc ttcgagctgc aaggtccgca ggagtccacc gctccgctga 21600
aactcacgcc ggggttgtgg acttccgcgt acctgcgcaa atttgtaccc gaagactacc 21660
acgcccatga gataaagttc tttgaggacc aatcgcgtcc gcagcacgcg gatctcacgg 21720
cctgcgtcat cacccagggc gcgatcctcg cccaattgca cgccatccaa aaatcccgcc 21780
aagagtttct tctgaaaaag ggtagagggg tctacctgga cccccagacg ggcgaggtgc 21840
tcaacccggg tctcccccag catgccgagg aagaagcagg agccgctagt ggaggagatg 21900
gaagaagaat gggacagcca ggcagaggag gacgaatggg aggaggagac agaggaggaa 21960
gaattggaag aggtggaaga ggagcaggca acagagcagc ccgtcgccgc accatccgcg 22020
ccggcagccc cgccggtcac ggatacaacc tccgctccgg tcaagcctcc tcgtagatgg 22080
gatcaagtga agggtgacgg taagcacgag cggcagggct accgatcatg gagggcccac 22140
aaagccgcga tcatcgcctg cttgcaagac tgcgggggga acatcgcttt cgcccgccgc 22200
tacctgctct tccaccgcgg ggtgaacatc ccccgcaacg tgttgcatta ctaccgtcac 22260
cttcacagct aagaaaaagc aagtcaaagg agtcgccgga ggaggaggag gaggcctgag 22320
gatcgcggcg aacgagccct tgaccaccag ggagctgagg aaccggatct tccccactct 22380
ttatgccatt tttcagcaga gtcgaggtca gcagcaagag ctcaaagtaa aaaaccggtc 22440
tctgcgctcg ctcacccgca gttgcttgta ccacaaaaac gaagatcagc tgcagcgcac 22500
tctcgaagac gccgaggctc tgttccacaa gtactgcgcg ctcactctta aagactaagg 22560
cgcgcccacc cggaaaaaag gcgggaatta cctcatcgcc accatgagca aggagattcc 22620
caccccttac atgtggagct atcagcccca aatgggcctg gccgcgggcg cctcccagga 22680
ctactccacc cgcatgaact ggctcagtgc cggcccctcg atgatctcac gggtcaacgg 22740
ggtccgcagt catcgaaacc agatattgtt ggagcaggcg gcggtcacct ccacgcccag 22800
ggcaaagctc aacccgcgta attggccctc caccctggtg tatcaggaaa tccccgggcc 22860
gactaccgta ctacttccgc gtgacgcact ggccgaagtc cgcatgacta actcaggtgt 22920
ccagctggcc ggcggcgctt cccggtgccc gctccgccca caatcgggta taaaaaccct 22980
ggtgatccga ggcagaggca cacagctcaa cgacgagttg gtgagctctt cgatcggtct 23040
gcgaccggac ggagtgttcc aactagccgg agccgggaga tcctccttca ctcccaacca 23100
ggcctacctg accttgcaga gcagctcttc ggagcctcgc tccggaggca tcggaaccct 23160
ccagtttgtg gaggagtttg tgccctcggt ctacttcaac cccttctcgg gatcgccagg 23220
cctctacccg gacgagttca taccgaactt cgacgcagtg agagaagcgg tggacggcta 23280
cgactgaatg tcccatggtg actcggctga gctcgctcgg ttgaggcatc tggaccactg 23340
ccgccgcctg cgctgcttcg cccgggagag ctgcggactc atctactttg agtttcccga 23400
ggagcacccc aacggccctg cacacggagt gcggatcacc gtagagggca ccaccgagtc 23460
tcacctggtc aggttcttca cccagcaacc cttcctggtc gagcgggacc ggggcgccac 23520
cacctacacc gtctactgca tctgtccaac cccgaagttg catgagaatt tttgttgtac 23580
tctttgtggt gagtttaata aaagctaaac tcttgcaata ctctggacct tgtcgtcgtc 23640
aactcaacga gaccgtctac ctcaccaacc agactgaggt aaaactcacc tgcagaccac 23700
acaagaccta tatcatctgg ttcttcgaga acacctcatt tgcagtctcc aacactcact 23760
gcactagtcc atgaactgat gttgattaaa agcccaaaaa ccaatcagcc ccttccccca 23820
tttccccatc ccccaattac tcataaaaaa taaatcattg gaattaatca ttcaataaag 23880
atcacttact tgaaatctga aagtatgtct ctggtgtagt tgttcagcag cacctcggta 23940
ccctcctccc agctctggta ctccagtccc cggcgggcgg cgaacttcct ccacaccttg 24000
aaagggatgt caaattcctg gtccacaatt ttcattgtct tccctctcag atggcaaaga 24060
ggctccgggt ggaagatgac ttcaaccccg tctaccccta tggctacgcg cggaatcaga 24120
atatcccctt cctcactccc ccctttgtct cctccgatgg attcaaaaac ttcccccctg 24180
gggtcctgtc acttaaactg gctgatccaa tcaccatcaa caatggggat gtctcactta 24240
aggtgggagg gggacttgct gtagagcaac agactggtaa cctaagcgta aaccctgatg 24300
cacccttgca agttgcaagt gataagctac agcttgctct ggctcctcca ttcgaggtca 24360
gagatggaaa gcttgcttta aaggcaggta atggattaaa agtactagat aattccatta 24420
ctggattgac tggattattg aatacacttg tggtattaac tggaagggga ataggaacgg 24480
aggaattaaa aaatgacgat ggtgtaacaa acaaaggagt cggcttgcgt gtaagacttg 24540
gagatgacgg cgggctgaca tttgataaaa agggtgattt agtagcctgg aataaaaaag 24600
atgacaggcg caccctgtgg acaacccctg acacatctcc aaattgcaaa atgagtacag 24660
aaaaggattc taaacttacg ttgacactta caaagtgtgg aagtcaggtt ctgggaaatg 24720
tatctttact tgcagttaca ggtgaatatc atcaaatgac tgctactaca aagaaggatg 24780
taaaaatatc tttactattt gatgagaatg gaattctatt accatcttcg tcccttagca 24840
aagattattg gaattacaga agtgatgatt ctattgtatc tcaaaaatat aataatgcag 24900
ttccattcat gccaaacctg acagcttatc caaaaccaag cgctcaaaat gcaaaaaact 24960
attcaagaac taaaatcata agtaatgtct acttaggtgc tcttacctac caacctgtaa 25020
ttatcactat tgcatttaat caggaaactg aaaatggatg tgcttattct ataacattta 25080
ccttcacttg gcaaaaagac tattctgccc aacagtttga tgttacatct tttaccttct 25140
catatcttac ccaagagaac aaagacaaag actaataaaa tgttttgaac tgaatttatg 25200
aatctttatt tatttttaca ccagcacggg tagtcagttt cccaccacca gcccatttca 25260
cagtgtaaac agtcctttct ccccggctgg ccttaaaaag catcatatca tgggtaacag 25320
acatattctt aggtgttata ttccacacgg tttcctgtcg agccaaacgc tcatcagtga 25380
tattaataaa ctccccgggc agctcactta agttcatgtc gctgtccagc tgctgagcca 25440
caggctgctg tccaacttgc ggttgcttaa cgggcggcga aggagaagtc cacgcctaca 25500
tgggggtaga gtcataatcg tgcatcagga tagggcggtg gtgctgcagc agcgcgcgaa 25560
taaactgctg ccgccgccgc tccgtcctgc aggaatacaa catggcagtg gtctcctcag 25620
cgatgattcg caccgcccgc agcataaggc gccttgtcct ccgggcacag cagcgcaccc 25680
tgatctcact taaatcagca cagtaactgc agcacagcac cacaatattg ttcaaaatcc 25740
cacagtgcaa ggcgctgtat ccaaagctca tggcggggac cacagaaccc acgtggccat 25800
cataccacaa gcgcaggtag attaagtggc gacccctcat aaacacgctg gacataaaca 25860
ttacctcttt tggcatgttg taattcacca cctcccggta ccatataaac ctctgattaa 25920
acatggcgcc atccaccacc atcctaaacc agctggccaa aacctgcccg ccggctatac 25980
actgcaggga accgggactg gaacaatgac agtggagagc ccaggactcg taaccatgga 26040
tcatcatgct cgtcatgata tcaatgttgg cacaacacag gcacacgtgc atacacttcc 26100
tcaggattac aagctcctcc cgcgttagaa ccatatccca gggaacaacc cattcctgaa 26160
tcagcgtaaa tcccacactg cagggaagac ctcgcacgta actcacgttg tgcattgtca 26220
aagtgttaca ttcgggcagc agcggatgat cctccagtat ggtagcgcgg gtttctgtct 26280
caaaaggagg tagacgatcc ctactgtacg gagtgcgccg agacaaccga gatcgtgttg 26340
gtcgtagtgt catgccaaat ggaacgccgg acgtagtcat tgaaatggat tctcttgcgt 26400
accttgtcgt acttctgcca gcagaaagtg gctcgggaac agcagatacc tttcctcctg 26460
ctgtccttcc gctgctgacg ctcagtcatc caactgaagt acagccattc ccgcaggttc 26520
tccagcagct cctgtgcatc tgatgaaaca aaagtcccgt cgatgcggat tccccttaaa 26580
acatcagcca ggacattgta ggccatccca atccagttaa tgcatcctga tctatcatga 26640
agaggaggtg ggggaagaac tggaagaacc atttttattc caagcggtct cgaaggacga 26700
taaagtgcaa gtcacgcagg tgacagcgtt ccccgccgct gtgctggtgg aaacagacag 26760
ccaggtcaaa acccactcta ttttcaaggt gctcgactgt ggcttcgagc agtggctcta 26820
cgcgtacatc cagcataaga atcacattaa aggctggacc tccatcgatt tcatcaatca 26880
tcaggttaca ctcattcacc atccccaggt aattctcatt tttccagcct tggattattt 26940
ctacaaattg ttggtgtaag tccactccgc acatgtggaa aagttcccac agcgccccct 27000
ccactttcat aatcaggcag accttcatat tagaaacaga tcctgctgct ccaccacctg 27060
cagcgtgttc aaaacaacaa gattcaatga ggttctgccc tctgccctca gctcacgtct 27120
cagcgtcagc tgcaaaaagt cactcaagtc ctcagccact acagctgaca attcagagcc 27180
agggctaagc gtgggactgg caagcgtgag tgagtacttt aatgctccaa agctagcacc 27240
caaaaactgc atgctggaat aagctctctt tgtgtcaccg gtgatgcctt ccaataggtg 27300
agtgataaag cgaggtagtt tttctttaat catttgagta atagaaaagt cctctaaata 27360
agtcactagg accccaggaa ccacaatgtg gtagctgaca gcgtgtcgct caagcatggt 27420
tagtagagat gagagtctga aaaacagaaa gcatgcacta aaccagagtt gccagtctca 27480
ctgaaggaaa aatcactctc tccagcagca aagtgcccac tgggtggccc tctcggacat 27540
acaaaaatcg atccgtgtgg ttaaagagca gcacagttag ctcctgtctt ctcccagcaa 27600
agatcacatc ggactgggtt agtatgcccc tggaatggta gtcattcaag gccataaatc 27660
tgccttggta gccattagga atcagcacgc tcactctcaa gtgaaccaaa accaccccat 27720
gcggaggaat gtggaaagat tctgggcaaa aaaaggtata tctattgcta gtcccttcct 27780
ggacgggagc aatccctcca gggctatcta tgaaagcata cagagattca gccatagctc 27840
agcccgctta ccagtagaca gagagcacag cagtacaagc gccaacagca gcgactgact 27900
acccactgac ccagctccct atttaaaggc accttacact gacgtaatga ccaaaggtct 27960
aaaaaccccg ccaaaaaaac acacacgccc tgggtgtttt tcgcgaaaac acttccgcgt 28020
tctcacttcc tcgtatcgat ttcgtgactc aacttccggg ttcccacgtt acgtcacttc 28080
tgcccttaca tgtaactcag ccgtagggcg ccatcttgcc cacgtccaaa atggcttcca 28140
tgtccggcca cgcctccgcg gcgaccgtta gccgtgcgtc gtgacgtcat ttgcatcacc 28200
gtttctcgtc caatcagcgt tggctccgcc ccaaaaccgt taaaattcaa aagctcattt 28260
gcatattaac ttttgtttac tttgtggggt atattattga tgatg 28305
<210> 7
<211> 30964
<212> DNA
<213> 人工序列
<220>
<223> Ad26.HVRPtr1.FLuc
<400> 7
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat ccaagtcaat gggaagaaac ttccacagat gctactacta 18000
ctactactca cagctttggc ctggctgcta tgaaggggga caatattaca tctgacggtt 18060
tgcagatagg aacagatgct acttctggag aggaaaaacc catctatgca gataaaactt 18120
tccagccaga acctcaaata ggggaagagt catggactga tactgacgga accaatgaaa 18180
aattcggagg aagagtcctt aaaaaggaca ctaaaatgaa accatgctat ggatcttttg 18240
ctagacctac taatgagaaa ggaggtcagg caaagttcaa accagttaat gaaggagaac 18300
aacctaaaga tctggatata gatatgaact tttttgatgg tagagatgca gctgctaact 18360
ttactccaga agtagtgttg tacactgaaa atgttaatct tgaaacacca gacactcatg 18420
tggtttacaa gccaggaacc tcagatgtga gttcccatgt caatttgggt cagcagtcca 18480
tgccaaacag acccaactac attggcttta gggacaactt tgtaggtctc atgtattaca 18540
acagcaccgg aaatatgggt gtgctggctg gtcaggcttc tcagttgaac gctgtggtcg 18600
acttgcaaga cagaaacacc gagttatctt accagctatt gctagattct ctgggtgaca 18660
gaaccagata ctttagcatg tggaactctg cggtggacag ttacgatcca gatgtcagga 18720
tcattgaaaa tcacggtgtg gaagatgaac ttccaaacta ttgcttccca ttggacgctg 18780
tgggtattac taaaacttat caaggtatca aaacgcaaaa tggtcaaact acaacgtggg 18840
aaaaggacac cagtgttagt acggccaatg aaataggcat tggcaacaat cttgccatgg 18900
agatcaacct gcaggccaac ctgtggaaga gttttctgta ctcgaacgtg gccctgtacc 18960
tgcccgactc ctacaagtac acgccggcca acgtcaagct gcccgccaac accaacacct 19020
acgagtacat gaacggccgc gtggtagccc cctcgctggt ggacgcctac atcaacatcg 19080
gcgcccgctg gtcgttggat cccatggaca acgtcaaccc cttcaaccac caccgcaatg 19140
cgggcctgcg ctaccgctcc atgctgctgg gcaacggccg ctacgtgccc ttccacatcc 19200
aagtgcccca aaagttcttt gccatcaaga acctgctcct gctcccgggc tcctacacct 19260
acgagtggaa cttccgcaag gacgtcaaca tgatcctgca gagttccctc ggcaacgacc 19320
tgcgcgtcga cggcgcctcc gtccgcttcg acagcgtcaa cctatacgcc actttcttcc 19380
ccatggcgca caacaccgct tcaaccttgg aagccatgct gcgcaacgac accaacgacc 19440
agtccttcaa cgactacctc tcggccgcca acatgctcta ccccatcccg gccaaggcca 19500
ccaacgtgcc catctccatc ccatcgcgca actgggccgc cttccgcggc tggagtttca 19560
cccggctcaa gaccaaggaa actccttccc tcggctcggg tttcgacccc tactttgtct 19620
actcgggctc catcccctac ctcgacggga ccttctacct caaccacacc ttcaagaagg 19680
tctccatcat gttcgactcc tcggtcagct ggcccggcaa cgaccggctg ctcacgccga 19740
acgagttcga gatcaagcgc agcgtcgacg gggagggcta caacgtggcc caatgcaaca 19800
tgaccaagga ctggttcctc gtccagatgc tctcccacta caacatcggc taccagggct 19860
tccacgtgcc cgagggctac aaggaccgca tgtactcctt cttccgcaac ttccagccca 19920
tgagcaggca ggtggtcgat gagatcaact acaaggacta caaggccgtc accctgccct 19980
tccagcacaa taactcgggc ttcaccggct acctcgcacc caccatgcgc caggggcagc 20040
cctaccccgc caacttcccc tacccgctca tcggtcagac agccgtgccc tccgtcaccc 20100
agaaaaagtt cctctgcgac agggtcatgt ggcgcatccc cttctccagc aacttcatgt 20160
ccatgggcgc cctcaccgac ctgggtcaga acatgctcta cgccaactcg gcccacgcgc 20220
tcgacatgac cttcgaggtg gaccccatgg atgagcccac cctcctctat cttctcttcg 20280
aagttttcga cgtggtcaga gtacaccagc cgcaccgcgg cgtcatcgag gccgtctacc 20340
tgcgcacgcc cttctccgcc ggcaacgcca ccacctaagc atgagcggct ccagcgaacg 20400
agagctcgcg gccatcgtgc gcgacctggg ctgcgggccc tactttttgg gcacccacga 20460
caagcgcttc ccgggctttc tcgccggcga caagctggcc tgcgccatcg tcaacacggc 20520
cggccgcgag accggaggcg tgcactggct cgccttcggc tggaacccgc gctcgcgcac 20580
ctgctacatg ttcgacccct ttgggttctc ggaccgccgg ctcaagcaga tttacagctt 20640
cgagtacgag gccatgctgc gccgcagcgc cctggcctcc tcgcccgacc gctgtctcag 20700
cctcgagcag tccactcaga ccgtgcaggg gcccgactcc gccgcctgcg gactcttctg 20760
ttgcatgttc ttgcatgcct tcgtgcactg gcccgaccga cccatggacg gaaaccccac 20820
catgaacttg ctgacggggg tgcccaacgg catgctacaa tcgccacagg tgctgcccac 20880
cctcaggcgc aaccaggagg aactctaccg cttcctcgcg cgccactccc cttactttcg 20940
ctcccaccgc gccgccatcg aacacgccac cgcttttgac aaaatgaaac aactgcgtgt 21000
atctcaataa acagcacttt tattttacat gcactggagt atatgcaagt tatttaaaag 21060
tcgaaggggt tctcgcgctc gtcgttgtgc gccgcgctgg ggagggccac gttgcggtac 21120
tggtacttgg gctgccactt gaactcgggg atcaccagtt tgggcactgg ggtctcgggg 21180
aaggtctcgc tccacatgcg ccggctcatc tgcagggcgc ccagcatgtc cggggcggag 21240
atcttgaaat cgcagttggg gccggtgctc tgcgcgcgcg agttgcggta cacggggttg 21300
cagcactgga acaccatcag actggggtac ttcacactag ccagcacgct cttgtcgctg 21360
atctgatcct tgtccagatc ctcggcgttg ctcaggccga acggggtcat cttgcacagc 21420
tggcgtccca ggaagggcac gctctgaggc ttgtggttac actcgcagtg cacgggcatc 21480
agcatcatcc ccgcgccgcg ctgcatattc gggtagaggg ccttgacaaa ggccgcgatc 21540
tgcttgaaag cttgctgggc cttggccccc tcgctgaaaa acaggccgca gctcttcccg 21600
ctgaactggt tattcccaca cccggcatcc tgcacgcagc agcgcgcgtc atggctggtc 21660
agttgcacca cgctccgtcc ccagcggttc tgggtcacct tagccttgct gggctgctcc 21720
ttcaacgcgc gctgcccgtt ctcgctggtc acatccatct ccaccacgtg gtccttgtgg 21780
atcatcatcg tcccgtgcag acacttgagc tggccttcca cctcggtgca gccgtgatcc 21840
cacagggcgc aaccggtgca ctcccagttc ttgtgcgcaa tcccgctgtg gctgaagatg 21900
taaccttgca acatgcggcc catgatggtg ctaaatgctt tctgggtggt gaaggtcagt 21960
tgcatcccgc gggcctcctc gttcatccag gtctggcaca tcttctggaa gatctcggtc 22020
tgctcgggca tgagcttgta agcatcgcgc aggccgctgt cgacgcggta gcgttccatc 22080
agcacgttca tggtatccat gcccttctcc caggacgaga ccagaggcag actcagaggg 22140
ttgcgtacgt tcaggacacc gggggtcgcg ggctcgacga tgcgttttcc gtccttgcct 22200
tccttcaata gaaccggcgg ctggctgaat cccactccca cgatcacggc atcttcctgg 22260
ggcatctctt cgtcggggtc taccttggtc acatgcttgg tctttctggc ttgcttcttt 22320
tttggagggc tgtccacggg gagcacgtcc tcctcggaag acccggagcc cacccgctga 22380
tactttcggc gcttggtggg cagaggaggt ggcggcgagg ggctcctctc ctgctccggc 22440
ggatagcgcg ccgacccgtg gccccggggc ggagtggcct ctcggcccat gaaccggcgc 22500
acgtcctgac tgccgccggc cattgtttcc taggggaaga tggaggagca gccgcgtaag 22560
caggagcagg aggaggactt aaccacccac gagcaaccca aaatcgagca ggacctgggc 22620
ttcgaagagc cggctcgtct agaaccccca caggatgaac aggagcacga gcaagacgca 22680
ggccaggagg agaccgacgc tgggctcgag catggctacc tgggaggaga ggaggatgtg 22740
ctgctgaaac acctgcagcg ccagtccctc atcctccggg acgccctggc cgaccggagc 22800
gaaacccccc tcagcgtcga ggagctgtgt cgggcctacg agctcaacct cttctcgccg 22860
cgcgtacccc ccaaacgcca gcccaacggc acctgcgagc ccaacccgcg tctcaacttc 22920
tatcccgtct ttgcggtccc cgaagccctc gccacctatc acatcttttt caagaaccaa 22980
aagatccccg tctcctgccg cgccaaccgc accagcgccg acgcgctcct cgctttgggg 23040
cccggcgcgc gcatacctga tatcgcttcc ctggaagagg tgcccaagat cttcgaaggg 23100
ctcggtcggg acgagacgcg cgcggcgaac gctctgaaag aaacagcaga ggaagagggt 23160
cacactagcg ccctggtaga gttggaaggc gacaacgcca ggctggccgt gctcaagcgc 23220
agcgtcgagc ttacccactt cgcctacccc gccgtcaacc tcccgcccaa ggtcatgcgt 23280
cgcatcatgg atcagctcat catgccccac atcgaggccc tcgatgaaag tcaggagcag 23340
cgccccgagg acgcccggcc cgtggtcagc gacgagatgc tcgcgcgctg gctcgggacc 23400
cgcgaccccc aggctttgga acagcggcgc aaactcatgc tggccgtggt cctggtcacc 23460
cttgagctcg aatgcatgcg ccgctttttc agcgaccccg agaccctgcg caaggtcgag 23520
gagaccctgc actacacttt caggcacggt ttcgtcaggc aggcctgcaa gatctccaac 23580
gtggagctga ccaacctggt ctcctgcctg gggatcctgc acgagaaccg cctgggccag 23640
accgtgctcc actctaccct gaagggcgag gcgcggcggg actatgtccg cgactgcgtc 23700
tttctctttc tctgccacac atggcaagcg gccatgggcg tgtggcagca gtgtctcgag 23760
gacgagaacc taaaggagct ggacaagctt cttgctagaa accttaaaaa gctgtggacg 23820
ggcttcgacg agcgcaccgt cgcctcggac ctggccgaga tcgtcttccc cgagcgcctg 23880
agacagacgc tgaaaggcgg gctgcccgac ttcatgagcc agagcatgtt gcaaaactac 23940
cgcactttca ttcttgagcg atcaggcatc ctgcccgcca cctgcaacgc cttcccctcc 24000
gactttgtac cgctgagcta ccgcgagtgt cccccgccgc tgtggagcca ctgctacctc 24060
ttgcagctgg ccaactacat cgcctaccac tcggacgtga tcgaggacgt gagcggcgag 24120
gggctgctcg agtgccactg tcgctgcaac ctgtgctccc cgcatcgctc cctggtctgc 24180
aacccccagc tcctgagcga gacccaggtc atcggtacct tcgagctgca aggtccgcag 24240
gagtccaccg ctccgctgaa actcacgccg gggttgtgga cttccgcgta cctgcgcaaa 24300
tttgtacccg aagactacca cgcccatgag ataaagttct ttgaggacca atcgcgtccg 24360
cagcacgcgg atctcacggc ctgcgtcatc acccagggcg cgatcctcgc ccaattgcac 24420
gccatccaaa aatcccgcca agagtttctt ctgaaaaagg gtagaggggt ctacctggac 24480
ccccagacgg gcgaggtgct caacccgggt ctcccccagc atgccgagga agaagcagga 24540
gccgctagtg gaggagatgg aagaagaatg ggacagccag gcagaggagg acgaatggga 24600
ggaggagaca gaggaggaag aattggaaga ggtggaagag gagcaggcaa cagagcagcc 24660
cgtcgccgca ccatccgcgc cggcagcccc gccggtcacg gatacaacct ccgctccggt 24720
caagcctcct cgtagatggg atcaagtgaa gggtgacggt aagcacgagc ggcagggcta 24780
ccgatcatgg agggcccaca aagccgcgat catcgcctgc ttgcaagact gcggggggaa 24840
catcgctttc gcccgccgct acctgctctt ccaccgcggg gtgaacatcc cccgcaacgt 24900
gttgcattac taccgtcacc ttcacagcta agaaaaagca agtcaaagga gtcgccggag 24960
gaggaggagg aggcctgagg atcgcggcga acgagccctt gaccaccagg gagctgagga 25020
accggatctt ccccactctt tatgccattt ttcagcagag tcgaggtcag cagcaagagc 25080
tcaaagtaaa aaaccggtct ctgcgctcgc tcacccgcag ttgcttgtac cacaaaaacg 25140
aagatcagct gcagcgcact ctcgaagacg ccgaggctct gttccacaag tactgcgcgc 25200
tcactcttaa agactaaggc gcgcccaccc ggaaaaaagg cgggaattac ctcatcgcca 25260
ccatgagcaa ggagattccc accccttaca tgtggagcta tcagccccaa atgggcctgg 25320
ccgcgggcgc ctcccaggac tactccaccc gcatgaactg gctcagtgcc ggcccctcga 25380
tgatctcacg ggtcaacggg gtccgcagtc atcgaaacca gatattgttg gagcaggcgg 25440
cggtcacctc cacgcccagg gcaaagctca acccgcgtaa ttggccctcc accctggtgt 25500
atcaggaaat ccccgggccg actaccgtac tacttccgcg tgacgcactg gccgaagtcc 25560
gcatgactaa ctcaggtgtc cagctggccg gcggcgcttc ccggtgcccg ctccgcccac 25620
aatcgggtat aaaaaccctg gtgatccgag gcagaggcac acagctcaac gacgagttgg 25680
tgagctcttc gatcggtctg cgaccggacg gagtgttcca actagccgga gccgggagat 25740
cctccttcac tcccaaccag gcctacctga ccttgcagag cagctcttcg gagcctcgct 25800
ccggaggcat cggaaccctc cagtttgtgg aggagtttgt gccctcggtc tacttcaacc 25860
ccttctcggg atcgccaggc ctctacccgg acgagttcat accgaacttc gacgcagtga 25920
gagaagcggt ggacggctac gactgaatgt cccatggtga ctcggctgag ctcgctcggt 25980
tgaggcatct ggaccactgc cgccgcctgc gctgcttcgc ccgggagagc tgcggactca 26040
tctactttga gtttcccgag gagcacccca acggccctgc acacggagtg cggatcaccg 26100
tagagggcac caccgagtct cacctggtca ggttcttcac ccagcaaccc ttcctggtcg 26160
agcgggaccg gggcgccacc acctacaccg tctactgcat ctgtccaacc ccgaagttgc 26220
atgagaattt ttgttgtact ctttgtggtg agtttaataa aagctaaact cttgcaatac 26280
tctggacctt gtcgtcgtca actcaacgag accgtctacc tcaccaacca gactgaggta 26340
aaactcacct gcagaccaca caagacctat atcatctggt tcttcgagaa cacctcattt 26400
gcagtctcca acactcactg cactagtcca tgaactgatg ttgattaaaa gcccaaaaac 26460
caatcagccc cttcccccat ttccccatcc cccaattact cataaaaaat aaatcattgg 26520
aattaatcat tcaataaaga tcacttactt gaaatctgaa agtatgtctc tggtgtagtt 26580
gttcagcagc acctcggtac cctcctccca gctctggtac tccagtcccc ggcgggcggc 26640
gaacttcctc cacaccttga aagggatgtc aaattcctgg tccacaattt tcattgtctt 26700
ccctctcaga tggcaaagag gctccgggtg gaagatgact tcaaccccgt ctacccctat 26760
ggctacgcgc ggaatcagaa tatccccttc ctcactcccc cctttgtctc ctccgatgga 26820
ttcaaaaact tcccccctgg ggtcctgtca cttaaactgg ctgatccaat caccatcaac 26880
aatggggatg tctcacttaa ggtgggaggg ggacttgctg tagagcaaca gactggtaac 26940
ctaagcgtaa accctgatgc acccttgcaa gttgcaagtg ataagctaca gcttgctctg 27000
gctcctccat tcgaggtcag agatggaaag cttgctttaa aggcaggtaa tggattaaaa 27060
gtactagata attccattac tggattgact ggattattga atacacttgt ggtattaact 27120
ggaaggggaa taggaacgga ggaattaaaa aatgacgatg gtgtaacaaa caaaggagtc 27180
ggcttgcgtg taagacttgg agatgacggc gggctgacat ttgataaaaa gggtgattta 27240
gtagcctgga ataaaaaaga tgacaggcgc accctgtgga caacccctga cacatctcca 27300
aattgcaaaa tgagtacaga aaaggattct aaacttacgt tgacacttac aaagtgtgga 27360
agtcaggttc tgggaaatgt atctttactt gcagttacag gtgaatatca tcaaatgact 27420
gctactacaa agaaggatgt aaaaatatct ttactatttg atgagaatgg aattctatta 27480
ccatcttcgt cccttagcaa agattattgg aattacagaa gtgatgattc tattgtatct 27540
caaaaatata ataatgcagt tccattcatg ccaaacctga cagcttatcc aaaaccaagc 27600
gctcaaaatg caaaaaacta ttcaagaact aaaatcataa gtaatgtcta cttaggtgct 27660
cttacctacc aacctgtaat tatcactatt gcatttaatc aggaaactga aaatggatgt 27720
gcttattcta taacatttac cttcacttgg caaaaagact attctgccca acagtttgat 27780
gttacatctt ttaccttctc atatcttacc caagagaaca aagacaaaga ctaataaaat 27840
gttttgaact gaatttatga atctttattt atttttacac cagcacgggt agtcagtttc 27900
ccaccaccag cccatttcac agtgtaaaca gtcctttctc cccggctggc cttaaaaagc 27960
atcatatcat gggtaacaga catattctta ggtgttatat tccacacggt ttcctgtcga 28020
gccaaacgct catcagtgat attaataaac tccccgggca gctcacttaa gttcatgtcg 28080
ctgtccagct gctgagccac aggctgctgt ccaacttgcg gttgcttaac gggcggcgaa 28140
ggagaagtcc acgcctacat gggggtagag tcataatcgt gcatcaggat agggcggtgg 28200
tgctgcagca gcgcgcgaat aaactgctgc cgccgccgct ccgtcctgca ggaatacaac 28260
atggcagtgg tctcctcagc gatgattcgc accgcccgca gcataaggcg ccttgtcctc 28320
cgggcacagc agcgcaccct gatctcactt aaatcagcac agtaactgca gcacagcacc 28380
acaatattgt tcaaaatccc acagtgcaag gcgctgtatc caaagctcat ggcggggacc 28440
acagaaccca cgtggccatc ataccacaag cgcaggtaga ttaagtggcg acccctcata 28500
aacacgctgg acataaacat tacctctttt ggcatgttgt aattcaccac ctcccggtac 28560
catataaacc tctgattaaa catggcgcca tccaccacca tcctaaacca gctggccaaa 28620
acctgcccgc cggctataca ctgcagggaa ccgggactgg aacaatgaca gtggagagcc 28680
caggactcgt aaccatggat catcatgctc gtcatgatat caatgttggc acaacacagg 28740
cacacgtgca tacacttcct caggattaca agctcctccc gcgttagaac catatcccag 28800
ggaacaaccc attcctgaat cagcgtaaat cccacactgc agggaagacc tcgcacgtaa 28860
ctcacgttgt gcattgtcaa agtgttacat tcgggcagca gcggatgatc ctccagtatg 28920
gtagcgcggg tttctgtctc aaaaggaggt agacgatccc tactgtacgg agtgcgccga 28980
gacaaccgag atcgtgttgg tcgtagtgtc atgccaaatg gaacgccgga cgtagtcatt 29040
gaaatggatt ctcttgcgta ccttgtcgta cttctgccag cagaaagtgg ctcgggaaca 29100
gcagatacct ttcctcctgc tgtccttccg ctgctgacgc tcagtcatcc aactgaagta 29160
cagccattcc cgcaggttct ccagcagctc ctgtgcatct gatgaaacaa aagtcccgtc 29220
gatgcggatt ccccttaaaa catcagccag gacattgtag gccatcccaa tccagttaat 29280
gcatcctgat ctatcatgaa gaggaggtgg gggaagaact ggaagaacca tttttattcc 29340
aagcggtctc gaaggacgat aaagtgcaag tcacgcaggt gacagcgttc cccgccgctg 29400
tgctggtgga aacagacagc caggtcaaaa cccactctat tttcaaggtg ctcgactgtg 29460
gcttcgagca gtggctctac gcgtacatcc agcataagaa tcacattaaa ggctggacct 29520
ccatcgattt catcaatcat caggttacac tcattcacca tccccaggta attctcattt 29580
ttccagcctt ggattatttc tacaaattgt tggtgtaagt ccactccgca catgtggaaa 29640
agttcccaca gcgccccctc cactttcata atcaggcaga ccttcatatt agaaacagat 29700
cctgctgctc caccacctgc agcgtgttca aaacaacaag attcaatgag gttctgccct 29760
ctgccctcag ctcacgtctc agcgtcagct gcaaaaagtc actcaagtcc tcagccacta 29820
cagctgacaa ttcagagcca gggctaagcg tgggactggc aagcgtgagt gagtacttta 29880
atgctccaaa gctagcaccc aaaaactgca tgctggaata agctctcttt gtgtcaccgg 29940
tgatgccttc caataggtga gtgataaagc gaggtagttt ttctttaatc atttgagtaa 30000
tagaaaagtc ctctaaataa gtcactagga ccccaggaac cacaatgtgg tagctgacag 30060
cgtgtcgctc aagcatggtt agtagagatg agagtctgaa aaacagaaag catgcactaa 30120
accagagttg ccagtctcac tgaaggaaaa atcactctct ccagcagcaa agtgcccact 30180
gggtggccct ctcggacata caaaaatcga tccgtgtggt taaagagcag cacagttagc 30240
tcctgtcttc tcccagcaaa gatcacatcg gactgggtta gtatgcccct ggaatggtag 30300
tcattcaagg ccataaatct gccttggtag ccattaggaa tcagcacgct cactctcaag 30360
tgaaccaaaa ccaccccatg cggaggaatg tggaaagatt ctgggcaaaa aaaggtatat 30420
ctattgctag tcccttcctg gacgggagca atccctccag ggctatctat gaaagcatac 30480
agagattcag ccatagctca gcccgcttac cagtagacag agagcacagc agtacaagcg 30540
ccaacagcag cgactgacta cccactgacc cagctcccta tttaaaggca ccttacactg 30600
acgtaatgac caaaggtcta aaaaccccgc caaaaaaaca cacacgccct gggtgttttt 30660
cgcgaaaaca cttccgcgtt ctcacttcct cgtatcgatt tcgtgactca acttccgggt 30720
tcccacgtta cgtcacttct gcccttacat gtaactcagc cgtagggcgc catcttgccc 30780
acgtccaaaa tggcttccat gtccggccac gcctccgcgg cgaccgttag ccgtgcgtcg 30840
tgacgtcatt tgcatcaccg tttctcgtcc aatcagcgtt ggctccgccc caaaaccgtt 30900
aaaattcaaa agctcatttg catattaact tttgtttact ttgtggggta tattattgat 30960
gatg 30964
<210> 8
<211> 30940
<212> PRT
<213> 人工序列
<220>
<223> Ad26.HVRPtr12.FLuc
<400> 8
Cys Ala Thr Cys Ala Thr Cys Ala Ala Thr Ala Ala Thr Ala Thr Ala
1 5 10 15
Cys Cys Cys Cys Ala Cys Ala Ala Ala Gly Thr Ala Ala Ala Cys Ala
20 25 30
Ala Ala Ala Gly Thr Thr Ala Ala Thr Ala Thr Gly Cys Ala Ala Ala
35 40 45
Thr Gly Ala Gly Cys Thr Thr Thr Thr Gly Ala Ala Thr Thr Thr Thr
50 55 60
Ala Ala Cys Gly Gly Thr Thr Thr Thr Gly Gly Gly Gly Cys Gly Gly
65 70 75 80
Ala Gly Cys Cys Ala Ala Cys Gly Cys Thr Gly Ala Thr Thr Gly Gly
85 90 95
Ala Cys Gly Ala Gly Ala Ala Ala Cys Gly Gly Thr Gly Ala Thr Gly
100 105 110
Cys Ala Ala Ala Thr Gly Ala Cys Gly Thr Cys Ala Cys Gly Ala Cys
115 120 125
Gly Cys Ala Cys Gly Gly Cys Thr Ala Ala Cys Gly Gly Thr Cys Gly
130 135 140
Cys Cys Gly Cys Gly Gly Ala Gly Gly Cys Gly Thr Gly Gly Cys Cys
145 150 155 160
Thr Ala Gly Cys Cys Cys Gly Gly Ala Ala Gly Cys Ala Ala Gly Thr
165 170 175
Cys Gly Cys Gly Gly Gly Gly Cys Thr Gly Ala Thr Gly Ala Cys Gly
180 185 190
Thr Ala Thr Ala Ala Ala Ala Ala Ala Gly Cys Gly Gly Ala Cys Thr
195 200 205
Thr Thr Ala Gly Ala Cys Cys Cys Gly Gly Ala Ala Ala Cys Gly Gly
210 215 220
Cys Cys Gly Ala Thr Thr Thr Thr Cys Cys Cys Gly Cys Gly Gly Cys
225 230 235 240
Cys Ala Cys Gly Cys Cys Cys Gly Gly Ala Thr Ala Thr Gly Ala Gly
245 250 255
Gly Thr Ala Ala Thr Thr Cys Thr Gly Gly Gly Cys Gly Gly Ala Thr
260 265 270
Gly Cys Ala Ala Gly Thr Gly Ala Ala Ala Thr Thr Ala Gly Gly Thr
275 280 285
Cys Ala Thr Thr Thr Thr Gly Gly Cys Gly Cys Gly Ala Ala Ala Ala
290 295 300
Cys Thr Gly Ala Ala Thr Gly Ala Gly Gly Ala Ala Gly Thr Gly Ala
305 310 315 320
Ala Ala Ala Gly Cys Gly Ala Ala Ala Ala Ala Thr Ala Cys Cys Gly
325 330 335
Gly Thr Cys Cys Cys Thr Cys Cys Cys Ala Gly Gly Gly Cys Gly Gly
340 345 350
Ala Ala Thr Ala Thr Thr Thr Ala Cys Cys Gly Ala Gly Gly Gly Cys
355 360 365
Cys Gly Ala Gly Ala Gly Ala Cys Thr Thr Thr Gly Ala Cys Cys Gly
370 375 380
Ala Thr Thr Ala Cys Gly Thr Gly Gly Gly Gly Gly Thr Thr Thr Cys
385 390 395 400
Gly Ala Thr Thr Gly Cys Gly Gly Thr Gly Thr Thr Thr Thr Thr Thr
405 410 415
Thr Cys Gly Cys Gly Ala Ala Thr Thr Thr Cys Cys Gly Cys Gly Thr
420 425 430
Cys Cys Gly Thr Gly Thr Cys Ala Ala Ala Gly Thr Cys Cys Gly Gly
435 440 445
Thr Gly Thr Thr Thr Ala Thr Gly Thr Cys Ala Cys Ala Gly Ala Thr
450 455 460
Cys Ala Gly Cys Thr Gly Ala Cys Cys Thr Ala Gly Gly Thr Gly Gly
465 470 475 480
Thr Cys Ala Ala Thr Ala Thr Thr Gly Gly Cys Cys Ala Thr Thr Ala
485 490 495
Gly Cys Cys Ala Thr Ala Thr Thr Ala Thr Thr Cys Ala Thr Thr Gly
500 505 510
Gly Thr Thr Ala Thr Ala Thr Ala Gly Cys Ala Thr Ala Ala Ala Thr
515 520 525
Cys Ala Ala Thr Ala Thr Thr Gly Gly Cys Thr Ala Thr Thr Gly Gly
530 535 540
Cys Cys Ala Thr Thr Gly Cys Ala Thr Ala Cys Gly Thr Thr Gly Thr
545 550 555 560
Ala Thr Cys Cys Ala Thr Ala Thr Cys Ala Thr Ala Ala Thr Ala Thr
565 570 575
Gly Thr Ala Cys Ala Thr Thr Thr Ala Thr Ala Thr Thr Gly Gly Cys
580 585 590
Thr Cys Ala Thr Gly Thr Cys Cys Ala Ala Cys Ala Thr Thr Ala Cys
595 600 605
Cys Gly Cys Cys Ala Thr Gly Thr Thr Gly Ala Cys Ala Thr Thr Gly
610 615 620
Ala Thr Thr Ala Thr Thr Gly Ala Thr Thr Ala Gly Thr Thr Ala Thr
625 630 635 640
Thr Ala Ala Thr Ala Gly Thr Ala Ala Thr Cys Ala Ala Thr Thr Ala
645 650 655
Cys Gly Gly Gly Gly Thr Cys Ala Thr Thr Ala Gly Thr Thr Cys Ala
660 665 670
Thr Ala Gly Cys Cys Cys Ala Thr Ala Thr Ala Thr Gly Gly Ala Gly
675 680 685
Thr Thr Cys Cys Gly Cys Gly Thr Thr Ala Cys Ala Thr Ala Ala Cys
690 695 700
Thr Thr Ala Cys Gly Gly Thr Ala Ala Ala Thr Gly Gly Cys Cys Cys
705 710 715 720
Gly Cys Cys Thr Gly Gly Cys Thr Gly Ala Cys Cys Gly Cys Cys Cys
725 730 735
Ala Ala Cys Gly Ala Cys Cys Cys Cys Cys Gly Cys Cys Cys Ala Thr
740 745 750
Thr Gly Ala Cys Gly Thr Cys Ala Ala Thr Ala Ala Thr Gly Ala Cys
755 760 765
Gly Thr Ala Thr Gly Thr Thr Cys Cys Cys Ala Thr Ala Gly Thr Ala
770 775 780
Ala Cys Gly Cys Cys Ala Ala Thr Ala Gly Gly Gly Ala Cys Thr Thr
785 790 795 800
Thr Cys Cys Ala Thr Thr Gly Ala Cys Gly Thr Cys Ala Ala Thr Gly
805 810 815
Gly Gly Thr Gly Gly Ala Gly Thr Ala Thr Thr Thr Ala Cys Gly Gly
820 825 830
Thr Ala Ala Ala Cys Thr Gly Cys Cys Cys Ala Cys Thr Thr Gly Gly
835 840 845
Cys Ala Gly Thr Ala Cys Ala Thr Cys Ala Ala Gly Thr Gly Thr Ala
850 855 860
Thr Cys Ala Thr Ala Thr Gly Cys Cys Ala Ala Gly Thr Ala Cys Gly
865 870 875 880
Cys Cys Cys Cys Cys Thr Ala Thr Thr Gly Ala Cys Gly Thr Cys Ala
885 890 895
Ala Thr Gly Ala Cys Gly Gly Thr Ala Ala Ala Thr Gly Gly Cys Cys
900 905 910
Cys Gly Cys Cys Thr Gly Gly Cys Ala Thr Thr Ala Thr Gly Cys Cys
915 920 925
Cys Ala Gly Thr Ala Cys Ala Thr Gly Ala Cys Cys Thr Thr Ala Thr
930 935 940
Gly Gly Gly Ala Cys Thr Thr Thr Cys Cys Thr Ala Cys Thr Thr Gly
945 950 955 960
Gly Cys Ala Gly Thr Ala Cys Ala Thr Cys Thr Ala Cys Gly Thr Ala
965 970 975
Thr Thr Ala Gly Thr Cys Ala Thr Cys Gly Cys Thr Ala Thr Thr Ala
980 985 990
Cys Cys Ala Thr Gly Gly Thr Gly Ala Thr Gly Cys Gly Gly Thr Thr
995 1000 1005
Thr Thr Gly Gly Cys Ala Gly Thr Ala Cys Ala Thr Cys Ala Ala
1010 1015 1020
Thr Gly Gly Gly Cys Gly Thr Gly Gly Ala Thr Ala Gly Cys Gly
1025 1030 1035
Gly Thr Thr Thr Gly Ala Cys Thr Cys Ala Cys Gly Gly Gly Gly
1040 1045 1050
Ala Thr Thr Thr Cys Cys Ala Ala Gly Thr Cys Thr Cys Cys Ala
1055 1060 1065
Cys Cys Cys Cys Ala Thr Thr Gly Ala Cys Gly Thr Cys Ala Ala
1070 1075 1080
Thr Gly Gly Gly Ala Gly Thr Thr Thr Gly Thr Thr Thr Thr Gly
1085 1090 1095
Gly Cys Ala Cys Cys Ala Ala Ala Ala Thr Cys Ala Ala Cys Gly
1100 1105 1110
Gly Gly Ala Cys Thr Thr Thr Cys Cys Ala Ala Ala Ala Thr Gly
1115 1120 1125
Thr Cys Gly Thr Ala Ala Cys Ala Ala Cys Thr Cys Cys Gly Cys
1130 1135 1140
Cys Cys Cys Ala Thr Thr Gly Ala Cys Gly Cys Ala Ala Ala Thr
1145 1150 1155
Gly Gly Gly Cys Gly Gly Thr Ala Gly Gly Cys Gly Thr Gly Thr
1160 1165 1170
Ala Cys Gly Gly Thr Gly Gly Gly Ala Gly Gly Thr Cys Thr Ala
1175 1180 1185
Thr Ala Thr Ala Ala Gly Cys Ala Gly Ala Gly Cys Thr Cys Gly
1190 1195 1200
Thr Thr Thr Ala Gly Thr Gly Ala Ala Cys Cys Gly Thr Cys Ala
1205 1210 1215
Gly Ala Thr Cys Gly Cys Cys Thr Gly Gly Ala Gly Ala Cys Gly
1220 1225 1230
Cys Cys Ala Thr Cys Cys Ala Cys Gly Cys Thr Gly Thr Thr Thr
1235 1240 1245
Thr Gly Ala Cys Cys Thr Cys Cys Ala Thr Ala Gly Ala Ala Gly
1250 1255 1260
Ala Cys Ala Cys Cys Gly Gly Gly Ala Cys Cys Gly Ala Thr Cys
1265 1270 1275
Cys Ala Gly Cys Cys Thr Cys Cys Gly Cys Gly Gly Cys Cys Gly
1280 1285 1290
Gly Gly Ala Ala Cys Gly Gly Thr Gly Cys Ala Thr Thr Gly Gly
1295 1300 1305
Ala Ala Gly Cys Thr Thr Gly Gly Cys Ala Thr Thr Cys Cys Gly
1310 1315 1320
Gly Thr Ala Cys Thr Gly Thr Thr Gly Gly Thr Ala Ala Ala Gly
1325 1330 1335
Cys Cys Ala Cys Cys Ala Thr Gly Gly Ala Ala Gly Ala Cys Gly
1340 1345 1350
Cys Cys Ala Ala Ala Ala Ala Cys Ala Thr Ala Ala Ala Gly Ala
1355 1360 1365
Ala Ala Gly Gly Cys Cys Cys Gly Gly Cys Gly Cys Cys Ala Thr
1370 1375 1380
Thr Cys Thr Ala Thr Cys Cys Gly Cys Thr Gly Gly Ala Ala Gly
1385 1390 1395
Ala Thr Gly Gly Ala Ala Cys Cys Gly Cys Thr Gly Gly Ala Gly
1400 1405 1410
Ala Gly Cys Ala Ala Cys Thr Gly Cys Ala Thr Ala Ala Gly Gly
1415 1420 1425
Cys Thr Ala Thr Gly Ala Ala Gly Ala Gly Ala Thr Ala Cys Gly
1430 1435 1440
Cys Cys Cys Thr Gly Gly Thr Thr Cys Cys Thr Gly Gly Ala Ala
1445 1450 1455
Cys Ala Ala Thr Thr Gly Cys Thr Thr Thr Thr Ala Cys Ala Gly
1460 1465 1470
Ala Thr Gly Cys Ala Cys Ala Thr Ala Thr Cys Gly Ala Gly Gly
1475 1480 1485
Thr Gly Gly Ala Cys Ala Thr Cys Ala Cys Thr Thr Ala Cys Gly
1490 1495 1500
Cys Thr Gly Ala Gly Thr Ala Cys Thr Thr Cys Gly Ala Ala Ala
1505 1510 1515
Thr Gly Thr Cys Cys Gly Thr Thr Cys Gly Gly Thr Thr Gly Gly
1520 1525 1530
Cys Ala Gly Ala Ala Gly Cys Thr Ala Thr Gly Ala Ala Ala Cys
1535 1540 1545
Gly Ala Thr Ala Thr Gly Gly Gly Cys Thr Gly Ala Ala Thr Ala
1550 1555 1560
Cys Ala Ala Ala Thr Cys Ala Cys Ala Gly Ala Ala Thr Cys Gly
1565 1570 1575
Thr Cys Gly Thr Ala Thr Gly Cys Ala Gly Thr Gly Ala Ala Ala
1580 1585 1590
Ala Cys Thr Cys Thr Cys Thr Thr Cys Ala Ala Thr Thr Cys Thr
1595 1600 1605
Thr Thr Ala Thr Gly Cys Cys Gly Gly Thr Gly Thr Thr Gly Gly
1610 1615 1620
Gly Cys Gly Cys Gly Thr Thr Ala Thr Thr Thr Ala Thr Cys Gly
1625 1630 1635
Gly Ala Gly Thr Thr Gly Cys Ala Gly Thr Thr Gly Cys Gly Cys
1640 1645 1650
Cys Cys Gly Cys Gly Ala Ala Cys Gly Ala Cys Ala Thr Thr Thr
1655 1660 1665
Ala Thr Ala Ala Thr Gly Ala Ala Cys Gly Thr Gly Ala Ala Thr
1670 1675 1680
Thr Gly Cys Thr Cys Ala Ala Cys Ala Gly Thr Ala Thr Gly Gly
1685 1690 1695
Gly Cys Ala Thr Thr Thr Cys Gly Cys Ala Gly Cys Cys Thr Ala
1700 1705 1710
Cys Cys Gly Thr Gly Gly Thr Gly Thr Thr Cys Gly Thr Thr Thr
1715 1720 1725
Cys Cys Ala Ala Ala Ala Ala Gly Gly Gly Gly Thr Thr Gly Cys
1730 1735 1740
Ala Ala Ala Ala Ala Ala Thr Thr Thr Thr Gly Ala Ala Cys Gly
1745 1750 1755
Thr Gly Cys Ala Ala Ala Ala Ala Ala Ala Gly Cys Thr Cys Cys
1760 1765 1770
Cys Ala Ala Thr Cys Ala Thr Cys Cys Ala Ala Ala Ala Ala Ala
1775 1780 1785
Thr Thr Ala Thr Thr Ala Thr Cys Ala Thr Gly Gly Ala Thr Thr
1790 1795 1800
Cys Thr Ala Ala Ala Ala Cys Gly Gly Ala Thr Thr Ala Cys Cys
1805 1810 1815
Ala Gly Gly Gly Ala Thr Thr Thr Cys Ala Gly Thr Cys Gly Ala
1820 1825 1830
Thr Gly Thr Ala Cys Ala Cys Gly Thr Thr Cys Gly Thr Cys Ala
1835 1840 1845
Cys Ala Thr Cys Thr Cys Ala Thr Cys Thr Ala Cys Cys Thr Cys
1850 1855 1860
Cys Cys Gly Gly Thr Thr Thr Thr Ala Ala Thr Gly Ala Ala Thr
1865 1870 1875
Ala Cys Gly Ala Thr Thr Thr Thr Gly Thr Gly Cys Cys Ala Gly
1880 1885 1890
Ala Gly Thr Cys Cys Thr Thr Cys Gly Ala Thr Ala Gly Gly Gly
1895 1900 1905
Ala Cys Ala Ala Gly Ala Cys Ala Ala Thr Thr Gly Cys Ala Cys
1910 1915 1920
Thr Gly Ala Thr Cys Ala Thr Gly Ala Ala Cys Thr Cys Cys Thr
1925 1930 1935
Cys Thr Gly Gly Ala Thr Cys Thr Ala Cys Thr Gly Gly Thr Cys
1940 1945 1950
Thr Gly Cys Cys Thr Ala Ala Ala Gly Gly Thr Gly Thr Cys Gly
1955 1960 1965
Cys Thr Cys Thr Gly Cys Cys Thr Cys Ala Thr Ala Gly Ala Ala
1970 1975 1980
Cys Thr Gly Cys Cys Thr Gly Cys Gly Thr Gly Ala Gly Ala Thr
1985 1990 1995
Thr Cys Thr Cys Gly Cys Ala Thr Gly Cys Cys Ala Gly Ala Gly
2000 2005 2010
Ala Thr Cys Cys Thr Ala Thr Thr Thr Thr Thr Gly Gly Cys Ala
2015 2020 2025
Ala Thr Cys Ala Ala Ala Thr Cys Ala Thr Thr Cys Cys Gly Gly
2030 2035 2040
Ala Thr Ala Cys Thr Gly Cys Gly Ala Thr Thr Thr Thr Ala Ala
2045 2050 2055
Gly Thr Gly Thr Thr Gly Thr Thr Cys Cys Ala Thr Thr Cys Cys
2060 2065 2070
Ala Thr Cys Ala Cys Gly Gly Thr Thr Thr Thr Gly Gly Ala Ala
2075 2080 2085
Thr Gly Thr Thr Thr Ala Cys Thr Ala Cys Ala Cys Thr Cys Gly
2090 2095 2100
Gly Ala Thr Ala Thr Thr Thr Gly Ala Thr Ala Thr Gly Thr Gly
2105 2110 2115
Gly Ala Thr Thr Thr Cys Gly Ala Gly Thr Cys Gly Thr Cys Thr
2120 2125 2130
Thr Ala Ala Thr Gly Thr Ala Thr Ala Gly Ala Thr Thr Thr Gly
2135 2140 2145
Ala Ala Gly Ala Ala Gly Ala Gly Cys Thr Gly Thr Thr Thr Cys
2150 2155 2160
Thr Gly Ala Gly Gly Ala Gly Cys Cys Thr Thr Cys Ala Gly Gly
2165 2170 2175
Ala Thr Thr Ala Cys Ala Ala Gly Ala Thr Thr Cys Ala Ala Ala
2180 2185 2190
Gly Thr Gly Cys Gly Cys Thr Gly Cys Thr Gly Gly Thr Gly Cys
2195 2200 2205
Cys Ala Ala Cys Cys Cys Thr Ala Thr Thr Cys Thr Cys Cys Thr
2210 2215 2220
Thr Cys Thr Thr Cys Gly Cys Cys Ala Ala Ala Ala Gly Cys Ala
2225 2230 2235
Cys Thr Cys Thr Gly Ala Thr Thr Gly Ala Cys Ala Ala Ala Thr
2240 2245 2250
Ala Cys Gly Ala Thr Thr Thr Ala Thr Cys Thr Ala Ala Thr Thr
2255 2260 2265
Thr Ala Cys Ala Cys Gly Ala Ala Ala Thr Thr Gly Cys Thr Thr
2270 2275 2280
Cys Thr Gly Gly Thr Gly Gly Cys Gly Cys Thr Cys Cys Cys Cys
2285 2290 2295
Thr Cys Thr Cys Thr Ala Ala Gly Gly Ala Ala Gly Thr Cys Gly
2300 2305 2310
Gly Gly Gly Ala Ala Gly Cys Gly Gly Thr Thr Gly Cys Cys Ala
2315 2320 2325
Ala Gly Ala Gly Gly Thr Thr Cys Cys Ala Thr Cys Thr Gly Cys
2330 2335 2340
Cys Ala Gly Gly Thr Ala Thr Cys Ala Gly Gly Cys Ala Ala Gly
2345 2350 2355
Gly Ala Thr Ala Thr Gly Gly Gly Cys Thr Cys Ala Cys Thr Gly
2360 2365 2370
Ala Gly Ala Cys Thr Ala Cys Ala Thr Cys Ala Gly Cys Thr Ala
2375 2380 2385
Thr Thr Cys Thr Gly Ala Thr Thr Ala Cys Ala Cys Cys Cys Gly
2390 2395 2400
Ala Gly Gly Gly Gly Gly Ala Thr Gly Ala Thr Ala Ala Ala Cys
2405 2410 2415
Cys Gly Gly Gly Cys Gly Cys Gly Gly Thr Cys Gly Gly Thr Ala
2420 2425 2430
Ala Ala Gly Thr Thr Gly Thr Thr Cys Cys Ala Thr Thr Thr Thr
2435 2440 2445
Thr Thr Gly Ala Ala Gly Cys Gly Ala Ala Gly Gly Thr Thr Gly
2450 2455 2460
Thr Gly Gly Ala Thr Cys Thr Gly Gly Ala Thr Ala Cys Cys Gly
2465 2470 2475
Gly Gly Ala Ala Ala Ala Cys Gly Cys Thr Gly Gly Gly Cys Gly
2480 2485 2490
Thr Thr Ala Ala Thr Cys Ala Ala Ala Gly Ala Gly Gly Cys Gly
2495 2500 2505
Ala Ala Cys Thr Gly Thr Gly Thr Gly Thr Gly Ala Gly Ala Gly
2510 2515 2520
Gly Thr Cys Cys Thr Ala Thr Gly Ala Thr Thr Ala Thr Gly Thr
2525 2530 2535
Cys Cys Gly Gly Thr Thr Ala Thr Gly Thr Ala Ala Ala Cys Ala
2540 2545 2550
Ala Thr Cys Cys Gly Gly Ala Ala Gly Cys Gly Ala Cys Cys Ala
2555 2560 2565
Ala Cys Gly Cys Cys Thr Thr Gly Ala Thr Thr Gly Ala Cys Ala
2570 2575 2580
Ala Gly Gly Ala Thr Gly Gly Ala Thr Gly Gly Cys Thr Ala Cys
2585 2590 2595
Ala Thr Thr Cys Thr Gly Gly Ala Gly Ala Cys Ala Thr Ala Gly
2600 2605 2610
Cys Thr Thr Ala Cys Thr Gly Gly Gly Ala Cys Gly Ala Ala Gly
2615 2620 2625
Ala Cys Gly Ala Ala Cys Ala Cys Thr Thr Cys Thr Thr Cys Ala
2630 2635 2640
Thr Cys Gly Thr Thr Gly Ala Cys Cys Gly Cys Cys Thr Gly Ala
2645 2650 2655
Ala Gly Thr Cys Thr Cys Thr Gly Ala Thr Thr Ala Ala Gly Thr
2660 2665 2670
Ala Cys Ala Ala Ala Gly Gly Cys Thr Ala Thr Cys Ala Gly Gly
2675 2680 2685
Thr Gly Gly Cys Thr Cys Cys Cys Gly Cys Thr Gly Ala Ala Thr
2690 2695 2700
Thr Gly Gly Ala Ala Thr Cys Cys Ala Thr Cys Thr Thr Gly Cys
2705 2710 2715
Thr Cys Cys Ala Ala Cys Ala Cys Cys Cys Cys Ala Ala Cys Ala
2720 2725 2730
Thr Cys Thr Thr Cys Gly Ala Cys Gly Cys Ala Gly Gly Thr Gly
2735 2740 2745
Thr Cys Gly Cys Ala Gly Gly Thr Cys Thr Thr Cys Cys Cys Gly
2750 2755 2760
Ala Cys Gly Ala Thr Gly Ala Cys Gly Cys Cys Gly Gly Thr Gly
2765 2770 2775
Ala Ala Cys Thr Thr Cys Cys Cys Gly Cys Cys Gly Cys Cys Gly
2780 2785 2790
Thr Thr Gly Thr Thr Gly Thr Thr Thr Thr Gly Gly Ala Gly Cys
2795 2800 2805
Ala Cys Gly Gly Ala Ala Ala Gly Ala Cys Gly Ala Thr Gly Ala
2810 2815 2820
Cys Gly Gly Ala Ala Ala Ala Ala Gly Ala Gly Ala Thr Cys Gly
2825 2830 2835
Thr Gly Gly Ala Thr Thr Ala Cys Gly Thr Cys Gly Cys Cys Ala
2840 2845 2850
Gly Thr Cys Ala Ala Gly Thr Ala Ala Cys Ala Ala Cys Cys Gly
2855 2860 2865
Cys Gly Ala Ala Ala Ala Ala Gly Thr Thr Gly Cys Gly Cys Gly
2870 2875 2880
Gly Ala Gly Gly Ala Gly Thr Thr Gly Thr Gly Thr Thr Thr Gly
2885 2890 2895
Thr Gly Gly Ala Cys Gly Ala Ala Gly Thr Ala Cys Cys Gly Ala
2900 2905 2910
Ala Ala Gly Gly Thr Cys Thr Thr Ala Cys Cys Gly Gly Ala Ala
2915 2920 2925
Ala Ala Cys Thr Cys Gly Ala Cys Gly Cys Ala Ala Gly Ala Ala
2930 2935 2940
Ala Ala Ala Thr Cys Ala Gly Ala Gly Ala Gly Ala Thr Cys Cys
2945 2950 2955
Thr Cys Ala Thr Ala Ala Ala Gly Gly Cys Cys Ala Ala Gly Ala
2960 2965 2970
Ala Gly Gly Gly Cys Gly Gly Ala Ala Ala Gly Ala Thr Cys Gly
2975 2980 2985
Cys Cys Gly Thr Gly Thr Ala Ala Thr Thr Cys Thr Ala Gly Ala
2990 2995 3000
Cys Gly Ala Gly Ala Thr Cys Cys Gly Ala Ala Cys Thr Thr Gly
3005 3010 3015
Thr Thr Thr Ala Thr Thr Gly Cys Ala Gly Cys Thr Thr Ala Thr
3020 3025 3030
Ala Ala Thr Gly Gly Thr Thr Ala Cys Ala Ala Ala Thr Ala Ala
3035 3040 3045
Ala Gly Cys Ala Ala Thr Ala Gly Cys Ala Thr Cys Ala Cys Ala
3050 3055 3060
Ala Ala Thr Thr Thr Cys Ala Cys Ala Ala Ala Thr Ala Ala Ala
3065 3070 3075
Gly Cys Ala Thr Thr Thr Thr Thr Thr Thr Cys Ala Cys Thr Gly
3080 3085 3090
Cys Ala Thr Thr Cys Thr Ala Gly Thr Thr Gly Thr Gly Gly Thr
3095 3100 3105
Thr Thr Gly Thr Cys Cys Ala Ala Ala Cys Thr Cys Ala Thr Cys
3110 3115 3120
Ala Ala Thr Gly Thr Ala Thr Cys Thr Thr Ala Thr Cys Ala Thr
3125 3130 3135
Gly Thr Cys Thr Ala Gly Ala Thr Cys Cys Ala Gly Gly Thr Ala
3140 3145 3150
Gly Gly Thr Thr Thr Gly Ala Gly Thr Ala Gly Thr Gly Gly Gly
3155 3160 3165
Cys Gly Thr Gly Gly Cys Thr Ala Ala Gly Gly Thr Gly Ala Cys
3170 3175 3180
Thr Ala Thr Ala Ala Ala Gly Gly Cys Gly Gly Gly Thr Gly Thr
3185 3190 3195
Cys Thr Thr Ala Cys Gly Ala Gly Gly Gly Thr Cys Thr Thr Thr
3200 3205 3210
Thr Thr Gly Cys Thr Thr Thr Thr Cys Thr Gly Cys Ala Gly Ala
3215 3220 3225
Cys Ala Thr Cys Ala Thr Gly Ala Ala Cys Gly Gly Gly Ala Cys
3230 3235 3240
Thr Gly Gly Cys Gly Gly Gly Gly Cys Cys Thr Thr Cys Gly Ala
3245 3250 3255
Ala Gly Gly Gly Gly Gly Gly Cys Thr Thr Thr Thr Thr Ala Gly
3260 3265 3270
Cys Cys Cys Thr Thr Ala Thr Thr Thr Gly Ala Cys Ala Ala Cys
3275 3280 3285
Cys Cys Gly Cys Cys Thr Gly Cys Cys Gly Gly Gly Ala Thr Gly
3290 3295 3300
Gly Gly Cys Cys Gly Gly Ala Gly Thr Thr Cys Gly Thr Cys Ala
3305 3310 3315
Gly Ala Ala Thr Gly Thr Gly Ala Thr Gly Gly Gly Ala Thr Cys
3320 3325 3330
Gly Ala Cys Gly Gly Thr Gly Gly Ala Thr Gly Gly Gly Cys Gly
3335 3340 3345
Cys Cys Cys Ala Gly Thr Gly Cys Thr Thr Cys Cys Ala Gly Cys
3350 3355 3360
Ala Ala Ala Thr Thr Cys Cys Thr Cys Gly Ala Cys Cys Ala Thr
3365 3370 3375
Gly Ala Cys Cys Thr Ala Cys Gly Cys Gly Ala Cys Cys Gly Thr
3380 3385 3390
Gly Gly Gly Gly Ala Ala Cys Thr Cys Gly Thr Cys Gly Cys Thr
3395 3400 3405
Cys Gly Ala Cys Ala Gly Cys Ala Cys Cys Gly Cys Cys Gly Cys
3410 3415 3420
Ala Gly Cys Cys Gly Cys Gly Gly Cys Ala Gly Cys Cys Gly Cys
3425 3430 3435
Ala Gly Cys Cys Gly Cys Cys Ala Thr Gly Ala Cys Ala Gly Cys
3440 3445 3450
Gly Ala Cys Gly Ala Gly Ala Cys Thr Gly Gly Cys Cys Thr Cys
3455 3460 3465
Gly Ala Gly Cys Thr Ala Cys Ala Thr Gly Cys Cys Cys Ala Gly
3470 3475 3480
Cys Ala Gly Cys Gly Gly Thr Ala Gly Thr Ala Gly Cys Cys Cys
3485 3490 3495
Cys Thr Cys Thr Gly Thr Gly Cys Cys Cys Ala Gly Thr Thr Cys
3500 3505 3510
Cys Ala Thr Cys Ala Thr Cys Gly Cys Cys Gly Ala Gly Gly Ala
3515 3520 3525
Gly Ala Ala Ala Cys Thr Gly Cys Thr Gly Gly Cys Cys Cys Thr
3530 3535 3540
Gly Cys Thr Gly Gly Cys Cys Gly Ala Gly Cys Thr Gly Gly Ala
3545 3550 3555
Ala Gly Cys Cys Cys Thr Gly Ala Gly Cys Cys Gly Cys Cys Ala
3560 3565 3570
Gly Cys Thr Gly Gly Cys Cys Gly Cys Cys Cys Thr Gly Ala Cys
3575 3580 3585
Cys Cys Ala Gly Cys Ala Gly Gly Thr Gly Thr Cys Cys Gly Ala
3590 3595 3600
Gly Cys Thr Cys Cys Gly Cys Gly Ala Ala Cys Ala Gly Cys Ala
3605 3610 3615
Gly Cys Ala Gly Cys Ala Gly Cys Ala Ala Ala Ala Thr Ala Ala
3620 3625 3630
Ala Thr Gly Ala Thr Thr Cys Ala Ala Thr Ala Ala Ala Cys Ala
3635 3640 3645
Cys Ala Gly Ala Thr Thr Cys Thr Gly Ala Thr Thr Cys Ala Ala
3650 3655 3660
Ala Cys Ala Gly Cys Ala Ala Ala Gly Cys Ala Thr Cys Thr Thr
3665 3670 3675
Thr Ala Thr Thr Ala Thr Thr Thr Ala Thr Thr Thr Thr Thr Thr
3680 3685 3690
Cys Gly Cys Gly Cys Gly Cys Gly Gly Thr Ala Gly Gly Cys Cys
3695 3700 3705
Cys Thr Gly Gly Thr Cys Cys Ala Cys Cys Thr Cys Thr Cys Cys
3710 3715 3720
Cys Gly Ala Thr Cys Ala Thr Thr Gly Ala Gly Ala Gly Thr Gly
3725 3730 3735
Cys Gly Gly Thr Gly Gly Ala Thr Thr Thr Thr Thr Thr Cys Cys
3740 3745 3750
Ala Gly Gly Ala Cys Cys Cys Gly Gly Thr Ala Gly Ala Gly Gly
3755 3760 3765
Thr Gly Gly Gly Ala Thr Thr Gly Gly Ala Thr Gly Thr Thr Gly
3770 3775 3780
Ala Gly Gly Thr Ala Cys Ala Thr Gly Gly Gly Cys Ala Thr Gly
3785 3790 3795
Ala Gly Cys Cys Cys Gly Thr Cys Cys Cys Gly Thr Gly Gly Gly
3800 3805 3810
Thr Gly Gly Ala Gly Gly Thr Ala Gly Cys Ala Cys Cys Ala Cys
3815 3820 3825
Thr Gly Cys Ala Thr Gly Gly Cys Cys Thr Cys Gly Thr Gly Cys
3830 3835 3840
Thr Cys Thr Gly Gly Gly Gly Thr Cys Gly Thr Gly Thr Thr Gly
3845 3850 3855
Thr Ala Gly Ala Thr Gly Ala Thr Cys Cys Ala Gly Thr Cys Ala
3860 3865 3870
Thr Ala Gly Cys Ala Gly Gly Gly Gly Cys Gly Cys Thr Gly Gly
3875 3880 3885
Gly Cys Gly Thr Gly Gly Thr Gly Cys Thr Gly Gly Ala Thr Gly
3890 3895 3900
Ala Thr Gly Thr Cys Cys Thr Thr Gly Ala Gly Gly Ala Gly Gly
3905 3910 3915
Ala Gly Ala Cys Thr Gly Ala Thr Gly Gly Cys Cys Ala Cys Gly
3920 3925 3930
Gly Gly Gly Ala Gly Cys Cys Cys Cys Thr Thr Gly Gly Thr Gly
3935 3940 3945
Thr Ala Gly Gly Thr Gly Thr Thr Gly Gly Cys Ala Ala Ala Ala
3950 3955 3960
Cys Gly Gly Thr Thr Gly Ala Gly Cys Thr Gly Gly Gly Ala Gly
3965 3970 3975
Gly Gly Ala Thr Gly Cys Ala Thr Gly Cys Gly Gly Gly Gly Gly
3980 3985 3990
Gly Ala Gly Ala Thr Gly Ala Thr Gly Thr Gly Cys Ala Gly Thr
3995 4000 4005
Thr Thr Gly Gly Cys Cys Thr Gly Gly Ala Thr Cys Thr Thr Gly
4010 4015 4020
Ala Gly Gly Thr Thr Gly Gly Cys Gly Ala Thr Gly Thr Thr Gly
4025 4030 4035
Cys Cys Ala Cys Cys Cys Ala Gly Ala Thr Cys Cys Cys Gly Cys
4040 4045 4050
Cys Gly Gly Gly Gly Gly Thr Thr Cys Ala Thr Gly Thr Thr Gly
4055 4060 4065
Thr Gly Cys Ala Gly Gly Ala Cys Cys Ala Cys Cys Ala Gly Ala
4070 4075 4080
Ala Cys Gly Gly Thr Gly Thr Ala Gly Cys Cys Cys Gly Thr Gly
4085 4090 4095
Cys Ala Cys Thr Thr Gly Gly Gly Gly Ala Ala Cys Thr Thr Gly
4100 4105 4110
Thr Cys Ala Thr Gly Cys Ala Ala Cys Thr Thr Gly Gly Ala Ala
4115 4120 4125
Gly Gly Gly Ala Ala Thr Gly Cys Gly Thr Gly Gly Ala Ala Gly
4130 4135 4140
Ala Ala Thr Thr Thr Gly Gly Ala Gly Ala Cys Gly Cys Cys Cys
4145 4150 4155
Thr Thr Gly Thr Gly Cys Cys Cys Gly Cys Cys Cys Ala Gly Gly
4160 4165 4170
Thr Thr Thr Thr Cys Cys Ala Thr Gly Cys Ala Cys Thr Cys Ala
4175 4180 4185
Thr Cys Cys Ala Thr Gly Ala Thr Gly Ala Thr Gly Gly Cys Ala
4190 4195 4200
Ala Thr Gly Gly Gly Cys Cys Cys Gly Thr Gly Gly Gly Cys Thr
4205 4210 4215
Gly Cys Gly Gly Cys Thr Thr Thr Gly Gly Cys Ala Ala Ala Gly
4220 4225 4230
Ala Cys Gly Thr Thr Thr Cys Thr Gly Gly Gly Gly Thr Cys Ala
4235 4240 4245
Gly Ala Gly Ala Cys Ala Thr Cys Gly Thr Ala Ala Thr Thr Ala
4250 4255 4260
Thr Gly Cys Thr Cys Cys Thr Gly Gly Gly Thr Gly Ala Gly Ala
4265 4270 4275
Thr Cys Ala Thr Cys Ala Thr Ala Ala Gly Ala Cys Ala Thr Thr
4280 4285 4290
Thr Thr Ala Ala Thr Gly Ala Ala Thr Thr Thr Gly Gly Gly Gly
4295 4300 4305
Cys Gly Gly Ala Gly Gly Gly Thr Gly Cys Cys Ala Gly Ala Thr
4310 4315 4320
Thr Gly Gly Gly Gly Gly Ala Cys Gly Ala Thr Gly Gly Thr Thr
4325 4330 4335
Cys Cys Cys Thr Cys Gly Gly Gly Cys Cys Cys Cys Gly Gly Gly
4340 4345 4350
Gly Cys Gly Ala Ala Gly Thr Thr Cys Cys Cys Cys Thr Cys Gly
4355 4360 4365
Cys Ala Gly Ala Thr Cys Thr Gly Cys Ala Thr Cys Thr Cys Cys
4370 4375 4380
Cys Ala Gly Gly Cys Thr Thr Thr Cys Ala Thr Cys Thr Cys Gly
4385 4390 4395
Gly Ala Gly Gly Gly Gly Gly Gly Gly Ala Thr Cys Ala Thr Gly
4400 4405 4410
Thr Cys Cys Ala Cys Cys Thr Gly Cys Gly Gly Gly Gly Cys Gly
4415 4420 4425
Ala Thr Gly Ala Ala Ala Ala Ala Ala Ala Cys Gly Gly Thr Thr
4430 4435 4440
Thr Cys Cys Gly Gly Gly Gly Cys Gly Gly Gly Gly Gly Thr Gly
4445 4450 4455
Ala Thr Gly Ala Gly Cys Thr Gly Cys Gly Ala Gly Gly Ala Gly
4460 4465 4470
Ala Gly Cys Ala Gly Gly Thr Thr Thr Cys Thr Cys Ala Ala Cys
4475 4480 4485
Ala Gly Cys Thr Gly Gly Gly Ala Cys Thr Thr Gly Cys Cys Gly
4490 4495 4500
Cys Ala Cys Cys Cys Gly Gly Thr Cys Gly Gly Gly Cys Cys Gly
4505 4510 4515
Thr Ala Gly Ala Thr Gly Ala Cys Cys Cys Cys Gly Ala Thr Gly
4520 4525 4530
Ala Cys Gly Gly Gly Thr Thr Gly Cys Ala Gly Gly Thr Gly Gly
4535 4540 4545
Thr Ala Gly Thr Thr Cys Ala Ala Gly Gly Ala Cys Ala Thr Gly
4550 4555 4560
Cys Ala Gly Cys Thr Gly Cys Cys Gly Thr Cys Gly Thr Cys Cys
4565 4570 4575
Cys Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Gly Gly Cys Cys
4580 4585 4590
Ala Cys Cys Thr Cys Gly Thr Thr Gly Ala Gly Cys Thr Thr Gly
4595 4600 4605
Thr Cys Thr Cys Thr Gly Ala Cys Thr Thr Gly Gly Ala Gly Gly
4610 4615 4620
Thr Thr Thr Thr Cys Cys Cys Gly Gly Ala Cys Gly Ala Gly Cys
4625 4630 4635
Thr Cys Gly Cys Cys Gly Ala Gly Gly Ala Gly Gly Cys Gly Gly
4640 4645 4650
Thr Cys Cys Cys Cys Gly Cys Cys Cys Ala Gly Cys Gly Ala Gly
4655 4660 4665
Ala Gly Ala Ala Gly Cys Thr Cys Thr Thr Gly Cys Ala Gly Gly
4670 4675 4680
Gly Ala Ala Gly Cys Ala Ala Ala Gly Thr Thr Thr Thr Thr Cys
4685 4690 4695
Ala Gly Gly Gly Gly Cys Thr Thr Gly Ala Gly Cys Cys Cys Gly
4700 4705 4710
Thr Cys Gly Gly Cys Cys Ala Thr Gly Gly Gly Cys Ala Thr Cys
4715 4720 4725
Thr Thr Gly Gly Cys Gly Ala Gly Gly Gly Thr Cys Thr Gly Cys
4730 4735 4740
Gly Ala Gly Ala Gly Gly Ala Gly Cys Thr Cys Cys Ala Gly Gly
4745 4750 4755
Cys Gly Gly Thr Cys Cys Cys Ala Gly Ala Gly Cys Thr Cys Gly
4760 4765 4770
Gly Thr Gly Ala Cys Gly Thr Gly Cys Thr Cys Thr Ala Cys Gly
4775 4780 4785
Gly Cys Ala Thr Cys Thr Cys Gly Ala Thr Cys Cys Ala Gly Cys
4790 4795 4800
Ala Gly Ala Cys Thr Thr Cys Cys Thr Cys Gly Thr Thr Thr Cys
4805 4810 4815
Gly Gly Gly Gly Gly Thr Thr Gly Gly Gly Ala Cys Gly Ala Cys
4820 4825 4830
Thr Gly Cys Gly Ala Cys Thr Gly Thr Ala Gly Gly Gly Cys Ala
4835 4840 4845
Cys Gly Ala Gly Ala Cys Gly Ala Thr Gly Gly Gly Cys Gly Thr
4850 4855 4860
Cys Cys Ala Gly Cys Gly Cys Gly Gly Cys Cys Ala Gly Cys Gly
4865 4870 4875
Thr Cys Ala Thr Gly Thr Cys Cys Thr Thr Cys Cys Ala Gly Gly
4880 4885 4890
Gly Thr Cys Thr Cys Ala Gly Gly Gly Thr Cys Cys Gly Cys Gly
4895 4900 4905
Thr Gly Ala Gly Gly Gly Thr Gly Gly Thr Cys Thr Cys Cys Gly
4910 4915 4920
Thr Cys Ala Cys Gly Gly Thr Gly Ala Ala Gly Gly Gly Gly Thr
4925 4930 4935
Gly Gly Gly Cys Cys Gly Cys Gly Gly Gly Cys Thr Gly Gly Gly
4940 4945 4950
Cys Gly Cys Thr Thr Gly Cys Ala Ala Gly Gly Gly Thr Gly Cys
4955 4960 4965
Gly Cys Thr Thr Gly Ala Gly Ala Cys Thr Cys Ala Thr Cys Cys
4970 4975 4980
Thr Gly Cys Thr Gly Gly Thr Gly Cys Thr Gly Ala Ala Ala Cys
4985 4990 4995
Gly Gly Gly Cys Ala Cys Gly Gly Thr Cys Thr Thr Cys Gly Cys
5000 5005 5010
Cys Cys Thr Gly Cys Gly Cys Gly Thr Cys Gly Gly Cys Gly Ala
5015 5020 5025
Gly Ala Thr Ala Gly Cys Ala Gly Thr Thr Gly Ala Cys Cys Ala
5030 5035 5040
Thr Gly Ala Gly Cys Thr Cys Gly Thr Ala Gly Thr Thr Gly Ala
5045 5050 5055
Gly Gly Gly Cys Cys Thr Cys Gly Gly Cys Gly Gly Cys Gly Thr
5060 5065 5070
Gly Gly Cys Cys Cys Thr Thr Gly Gly Cys Gly Cys Gly Gly Ala
5075 5080 5085
Gly Cys Thr Thr Gly Cys Cys Cys Thr Thr Gly Gly Ala Ala Gly
5090 5095 5100
Ala Gly Cys Gly Cys Cys Cys Gly Cys Ala Gly Gly Cys Gly Gly
5105 5110 5115
Gly Ala Cys Ala Gly Ala Gly Gly Ala Gly Gly Gly Ala Thr Thr
5120 5125 5130
Gly Cys Ala Gly Gly Gly Cys Gly Thr Ala Gly Ala Gly Cys Thr
5135 5140 5145
Thr Gly Gly Gly Cys Gly Cys Gly Ala Gly Ala Ala Ala Gly Ala
5150 5155 5160
Cys Gly Gly Ala Cys Thr Cys Gly Gly Gly Gly Gly Cys Gly Ala
5165 5170 5175
Ala Gly Gly Cys Gly Thr Cys Cys Gly Cys Thr Cys Cys Gly Cys
5180 5185 5190
Ala Gly Thr Gly Gly Gly Cys Gly Cys Ala Gly Ala Cys Gly Gly
5195 5200 5205
Thr Cys Thr Cys Gly Cys Ala Cys Thr Cys Gly Ala Cys Thr Ala
5210 5215 5220
Gly Cys Cys Ala Gly Gly Thr Gly Ala Gly Cys Thr Cys Gly Gly
5225 5230 5235
Gly Cys Thr Gly Cys Thr Cys Gly Gly Gly Gly Thr Cys Ala Ala
5240 5245 5250
Ala Ala Ala Cys Cys Ala Gly Thr Thr Thr Thr Cys Cys Cys Cys
5255 5260 5265
Cys Gly Thr Thr Cys Thr Thr Thr Thr Thr Gly Ala Thr Gly Cys
5270 5275 5280
Gly Cys Thr Thr Cys Thr Thr Ala Cys Cys Thr Cys Gly Cys Gly
5285 5290 5295
Thr Cys Thr Cys Cys Ala Thr Gly Ala Gly Thr Cys Thr Gly Thr
5300 5305 5310
Gly Thr Cys Cys Gly Cys Gly Cys Thr Cys Gly Gly Thr Gly Ala
5315 5320 5325
Cys Ala Ala Ala Cys Ala Gly Gly Cys Thr Gly Thr Cys Thr Gly
5330 5335 5340
Thr Gly Thr Cys Cys Cys Cys Gly Thr Ala Gly Ala Cys Gly Gly
5345 5350 5355
Ala Cys Thr Thr Gly Ala Thr Gly Gly Gly Cys Cys Thr Gly Thr
5360 5365 5370
Cys Cys Thr Gly Cys Ala Gly Gly Gly Gly Cys Gly Thr Cys Cys
5375 5380 5385
Cys Gly Cys Gly Gly Thr Cys Cys Thr Cys Cys Thr Cys Gly Thr
5390 5395 5400
Ala Gly Ala Gly Ala Ala Ala Cys Thr Cys Ala Gly Ala Cys Cys
5405 5410 5415
Ala Cys Thr Cys Thr Gly Ala Gly Ala Cys Gly Ala Ala Gly Gly
5420 5425 5430
Cys Gly Cys Gly Cys Gly Thr Cys Cys Ala Cys Gly Cys Cys Ala
5435 5440 5445
Ala Gly Ala Cys Ala Ala Ala Gly Gly Ala Gly Gly Cys Cys Ala
5450 5455 5460
Cys Gly Thr Gly Cys Gly Ala Gly Gly Gly Gly Thr Ala Gly Cys
5465 5470 5475
Gly Gly Thr Cys Gly Thr Thr Gly Thr Cys Cys Ala Cys Cys Ala
5480 5485 5490
Gly Gly Gly Gly Gly Thr Cys Cys Ala Cys Cys Thr Thr Thr Thr
5495 5500 5505
Cys Cys Ala Cys Gly Gly Thr Ala Thr Gly Cys Ala Gly Gly Cys
5510 5515 5520
Ala Cys Ala Thr Gly Thr Cys Cys Cys Cys Cys Thr Cys Cys Thr
5525 5530 5535
Cys Cys Gly Cys Ala Thr Cys Cys Ala Ala Gly Ala Ala Gly Gly
5540 5545 5550
Thr Gly Ala Thr Thr Gly Gly Cys Thr Thr Gly Thr Ala Gly Gly
5555 5560 5565
Thr Gly Thr Ala Gly Gly Cys Cys Ala Cys Gly Thr Gly Ala Cys
5570 5575 5580
Cys Thr Gly Gly Gly Gly Thr Thr Cys Cys Cys Gly Ala Cys Gly
5585 5590 5595
Gly Gly Gly Gly Gly Gly Thr Ala Thr Ala Ala Ala Ala Gly Gly
5600 5605 5610
Gly Gly Gly Cys Gly Gly Gly Thr Cys Thr Gly Thr Gly Cys Thr
5615 5620 5625
Cys Gly Thr Cys Cys Thr Cys Ala Cys Thr Cys Thr Cys Thr Thr
5630 5635 5640
Cys Cys Gly Cys Gly Thr Cys Gly Cys Thr Gly Thr Cys Cys Ala
5645 5650 5655
Cys Gly Ala Gly Cys Gly Cys Cys Ala Gly Cys Thr Gly Thr Thr
5660 5665 5670
Gly Gly Gly Gly Thr Ala Gly Gly Thr Ala Thr Thr Cys Cys Cys
5675 5680 5685
Thr Cys Thr Cys Ala Ala Gly Ala Gly Cys Gly Gly Gly Cys Ala
5690 5695 5700
Thr Gly Ala Cys Cys Thr Cys Gly Gly Cys Ala Cys Thr Cys Ala
5705 5710 5715
Gly Gly Thr Thr Gly Thr Cys Ala Gly Thr Thr Thr Cys Thr Ala
5720 5725 5730
Gly Ala Ala Ala Cys Gly Ala Gly Gly Ala Gly Gly Ala Thr Thr
5735 5740 5745
Thr Gly Ala Thr Gly Thr Gly Gly Gly Cys Cys Thr Gly Cys Cys
5750 5755 5760
Cys Thr Gly Cys Cys Gly Cys Gly Ala Thr Gly Cys Thr Thr Thr
5765 5770 5775
Thr Thr Ala Gly Gly Ala Gly Ala Cys Thr Thr Thr Cys Ala Thr
5780 5785 5790
Cys Cys Ala Thr Cys Thr Gly Gly Thr Cys Ala Gly Ala Ala Ala
5795 5800 5805
Ala Gly Ala Cys Thr Ala Thr Thr Thr Thr Thr Thr Thr Ala Thr
5810 5815 5820
Thr Gly Thr Cys Ala Ala Gly Cys Thr Thr Gly Gly Thr Gly Gly
5825 5830 5835
Cys Gly Ala Ala Gly Gly Ala Gly Cys Cys Ala Thr Ala Gly Ala
5840 5845 5850
Gly Gly Gly Cys Gly Thr Thr Thr Gly Ala Gly Ala Gly Ala Ala
5855 5860 5865
Gly Cys Thr Thr Gly Gly Cys Gly Ala Thr Gly Gly Ala Thr Cys
5870 5875 5880
Thr Cys Ala Thr Gly Gly Thr Cys Thr Gly Ala Thr Thr Thr Thr
5885 5890 5895
Thr Gly Thr Cys Ala Cys Gly Gly Thr Cys Gly Gly Cys Gly Cys
5900 5905 5910
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5915 5920 5925
Thr Gly Thr Thr Gly Ala Gly Cys Thr Gly Gly Ala Cys Ala Thr
5930 5935 5940
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5945 5950 5955
Ala Cys Thr Thr Cys Cys Ala Thr Thr Cys Gly Gly Gly Gly Ala
5960 5965 5970
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5975 5980 5985
Cys Gly Thr Cys Gly Gly Gly Cys Ala Cys Gly Ala Thr Cys Cys
5990 5995 6000
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6005 6010 6015
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6020 6025 6030
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6035 6040 6045
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6050 6055 6060
Gly Cys Ala Gly Gly Gly Gly Cys Thr Cys Gly Thr Thr Gly Gly
6065 6070 6075
Thr Cys Cys Ala Gly Cys Ala Gly Ala Gly Thr Cys Thr Gly Cys
6080 6085 6090
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6095 6100 6105
Ala Gly Ala Ala Cys Gly Gly Gly Gly Gly Cys Ala Gly Cys Ala
6110 6115 6120
Cys Ala Thr Cys Ala Ala Gly Cys Ala Gly Ala Thr Gly Cys Thr
6125 6130 6135
Cys Gly Thr Cys Ala Gly Gly Gly Gly Gly Gly Thr Cys Cys Gly
6140 6145 6150
Cys Ala Thr Cys Gly Ala Thr Gly Gly Thr Gly Ala Ala Gly Ala
6155 6160 6165
Thr Gly Cys Cys Cys Gly Gly Ala Cys Ala Gly Ala Gly Thr Thr
6170 6175 6180
Cys Cys Thr Thr Gly Thr Cys Ala Ala Ala Ala Thr Ala Ala Thr
6185 6190 6195
Cys Gly Ala Thr Thr Thr Thr Thr Gly Ala Gly Gly Ala Thr Gly
6200 6205 6210
Cys Ala Thr Cys Gly Thr Cys Cys Ala Ala Gly Gly Cys Cys Ala
6215 6220 6225
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6230 6235 6240
Cys Gly Gly Cys Cys Ala Gly Cys Gly Cys Thr Cys Gly Cys Thr
6245 6250 6255
Cys Gly Thr Ala Gly Gly Gly Gly Thr Thr Gly Ala Gly Gly Gly
6260 6265 6270
Gly Cys Gly Gly Ala Cys Cys Cys Cys Ala Ala Gly Gly Cys Ala
6275 6280 6285
Thr Gly Gly Gly Ala Thr Gly Cys Gly Thr Gly Ala Gly Gly Gly
6290 6295 6300
Cys Gly Gly Ala Gly Gly Cys Gly Thr Ala Cys Ala Thr Gly Cys
6305 6310 6315
Cys Gly Cys Ala Gly Ala Thr Gly Thr Cys Ala Thr Ala Gly Ala
6320 6325 6330
Cys Ala Thr Ala Gly Ala Thr Gly Gly Gly Cys Thr Cys Cys Gly
6335 6340 6345
Ala Gly Ala Gly Gly Ala Thr Gly Cys Cys Gly Ala Thr Gly Thr
6350 6355 6360
Ala Gly Gly Thr Gly Gly Gly Ala Thr Ala Gly Cys Ala Gly Cys
6365 6370 6375
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6380 6385 6390
Thr Thr Gly Cys Gly Cys Gly Cys Ala Cys Gly Thr Ala Gly Thr
6395 6400 6405
Cys Ala Thr Ala Cys Ala Ala Cys Thr Cys Gly Thr Gly Cys Gly
6410 6415 6420
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6425 6430 6435
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6440 6445 6450
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6455 6460 6465
Cys Gly Gly Cys Gly Cys Gly Gly Ala Ala Gly Ala Cys Gly Ala
6470 6475 6480
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6485 6490 6495
Cys Gly Thr Gly Cys Gly Ala Gly Thr Thr Gly Gly Ala Gly Gly
6500 6505 6510
Ala Gly Ala Thr Gly Gly Thr Gly Gly Gly Cys Cys Gly Thr Thr
6515 6520 6525
Gly Gly Ala Ala Gly Ala Thr Gly Thr Thr Ala Ala Ala Gly Thr
6530 6535 6540
Gly Gly Gly Cys Gly Thr Gly Ala Gly Gly Cys Ala Gly Gly Cys
6545 6550 6555
Gly Gly Ala Cys Cys Gly Ala Gly Thr Cys Gly Cys Gly Gly Ala
6560 6565 6570
Thr Gly Ala Ala Gly Thr Gly Cys Gly Cys Gly Thr Ala Gly Gly
6575 6580 6585
Ala Gly Thr Cys Thr Thr Gly Cys Ala Gly Cys Thr Thr Gly Gly
6590 6595 6600
Cys Gly Ala Cys Gly Ala Gly Cys Thr Cys Gly Gly Cys Gly Gly
6605 6610 6615
Thr Gly Ala Cys Gly Ala Gly Gly Ala Cys Gly Thr Cys Cys Ala
6620 6625 6630
Thr Gly Gly Cys Gly Cys Ala Gly Thr Ala Gly Thr Cys Cys Ala
6635 6640 6645
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6650 6655 6660
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6665 6670 6675
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6680 6685 6690
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6695 6700 6705
Gly Gly Gly Cys Gly Thr Ala Thr Thr Cys Cys Thr Cys Gly Thr
6710 6715 6720
Cys Ala Thr Cys Cys Thr Thr Cys Cys Ala Gly Thr Ala Cys Thr
6725 6730 6735
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6740 6745 6750
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6755 6760 6765
Gly Gly Thr Ala Ala Gly Ala Gly Cys Cys Cys Ala Gly Cys Ala
6770 6775 6780
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6785 6790 6795
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6800 6805 6810
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6815 6820 6825
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6830 6835 6840
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6845 6850 6855
Gly Gly Ala Gly Cys Gly Ala Gly Gly Thr Gly Thr Gly Cys Gly
6860 6865 6870
Thr Cys Ala Gly Gly Gly Cys Ala Ala Ala Gly Gly Thr Gly Thr
6875 6880 6885
Cys Cys Cys Thr Gly Ala Cys Cys Ala Thr Gly Ala Cys Thr Thr
6890 6895 6900
Thr Cys Ala Ala Gly Ala Ala Cys Thr Gly Gly Thr Ala Cys Thr
6905 6910 6915
Thr Gly Ala Ala Gly Thr Cys Cys Gly Ala Gly Thr Cys Gly Thr
6920 6925 6930
Cys Gly Cys Ala Gly Cys Cys Gly Cys Cys Gly Thr Gly Cys Thr
6935 6940 6945
Cys Cys Cys Ala Gly Ala Gly Cys Thr Cys Gly Ala Ala Ala Thr
6950 6955 6960
Cys Gly Gly Thr Gly Cys Gly Cys Thr Thr Cys Thr Thr Cys Gly
6965 6970 6975
Ala Gly Ala Gly Gly Gly Gly Gly Thr Thr Ala Gly Gly Cys Ala
6980 6985 6990
Gly Ala Gly Cys Gly Ala Ala Ala Gly Thr Gly Ala Cys Gly Thr
6995 7000 7005
Cys Ala Thr Thr Gly Ala Ala Gly Ala Gly Ala Ala Thr Cys Thr
7010 7015 7020
Thr Gly Cys Cys Thr Gly Cys Cys Cys Gly Cys Gly Gly Cys Ala
7025 7030 7035
Thr Gly Ala Ala Ala Thr Thr Gly Cys Gly Gly Gly Thr Gly Ala
7040 7045 7050
Thr Gly Cys Gly Gly Ala Ala Ala Gly Gly Gly Cys Cys Cys Gly
7055 7060 7065
Gly Gly Ala Cys Gly Gly Ala Gly Gly Cys Thr Cys Gly Gly Thr
7070 7075 7080
Thr Gly Thr Thr Gly Ala Thr Gly Ala Cys Cys Thr Gly Gly Gly
7085 7090 7095
Cys Gly Gly Cys Gly Ala Gly Gly Ala Cys Gly Ala Thr Cys Thr
7100 7105 7110
Cys Gly Thr Cys Ala Ala Ala Gly Cys Cys Gly Thr Thr Gly Ala
7115 7120 7125
Thr Gly Thr Thr Gly Thr Gly Cys Cys Cys Gly Ala Cys Gly Ala
7130 7135 7140
Thr Gly Thr Ala Gly Ala Gly Thr Thr Cys Cys Ala Thr Gly Ala
7145 7150 7155
Ala Thr Cys Gly Cys Gly Gly Gly Cys Gly Gly Cys Cys Thr Thr
7160 7165 7170
Thr Gly Ala Thr Gly Thr Gly Cys Gly Gly Cys Ala Gly Cys Thr
7175 7180 7185
Thr Thr Thr Thr Gly Ala Gly Cys Thr Cys Cys Thr Cys Gly Thr
7190 7195 7200
Ala Gly Gly Thr Gly Ala Gly Gly Thr Cys Cys Thr Cys Gly Gly
7205 7210 7215
Gly Gly Cys Ala Thr Thr Gly Cys Ala Gly Gly Cys Cys Gly Thr
7220 7225 7230
Gly Cys Thr Gly Cys Thr Cys Gly Ala Gly Cys Gly Cys Cys Cys
7235 7240 7245
Ala Cys Thr Cys Cys Thr Gly Gly Ala Gly Ala Thr Gly Thr Gly
7250 7255 7260
Gly Gly Thr Thr Gly Gly Cys Thr Thr Gly Cys Ala Thr Gly Ala
7265 7270 7275
Ala Gly Gly Ala Ala Gly Cys Cys Cys Ala Gly Ala Gly Cys Thr
7280 7285 7290
Cys Gly Cys Gly Gly Gly Cys Cys Ala Thr Gly Ala Gly Gly Gly
7295 7300 7305
Thr Cys Thr Gly Gly Ala Gly Cys Thr Cys Gly Thr Cys Gly Cys
7310 7315 7320
Gly Ala Ala Ala Gly Ala Gly Gly Cys Gly Gly Ala Ala Cys Thr
7325 7330 7335
Gly Cys Thr Gly Gly Cys Cys Cys Ala Cys Gly Gly Cys Cys Ala
7340 7345 7350
Thr Cys Thr Thr Thr Thr Cys Thr Gly Gly Gly Gly Thr Gly Ala
7355 7360 7365
Cys Gly Cys Ala Gly Thr Ala Gly Ala Ala Gly Gly Thr Gly Ala
7370 7375 7380
Gly Gly Gly Gly Gly Thr Cys Cys Cys Gly Cys Thr Cys Cys Cys
7385 7390 7395
Ala Gly Cys Gly Ala Thr Cys Cys Cys Ala Gly Cys Gly Thr Ala
7400 7405 7410
Ala Ala Cys Gly Cys Ala Cys Gly Gly Cys Gly Ala Gly Ala Thr
7415 7420 7425
Cys Gly Cys Gly Ala Gly Cys Gly Ala Gly Gly Gly Cys Gly Ala
7430 7435 7440
Cys Cys Ala Gly Cys Thr Cys Thr Gly Gly Gly Thr Cys Cys Cys
7445 7450 7455
Cys Gly Gly Ala Gly Ala Ala Thr Thr Thr Cys Ala Thr Gly Ala
7460 7465 7470
Cys Cys Ala Gly Cys Ala Thr Gly Ala Ala Gly Gly Gly Gly Ala
7475 7480 7485
Cys Gly Ala Gly Cys Thr Gly Cys Thr Thr Gly Cys Cys Gly Ala
7490 7495 7500
Ala Gly Gly Ala Cys Cys Cys Cys Ala Thr Cys Cys Ala Gly Gly
7505 7510 7515
Thr Gly Thr Ala Gly Gly Thr Thr Thr Cys Thr Ala Cys Ala Thr
7520 7525 7530
Cys Gly Thr Ala Gly Gly Thr Gly Ala Cys Ala Ala Ala Gly Ala
7535 7540 7545
Gly Cys Cys Gly Cys Thr Cys Cys Gly Thr Gly Cys Gly Ala Gly
7550 7555 7560
Gly Ala Thr Gly Ala Gly Ala Gly Cys Cys Gly Ala Thr Thr Gly
7565 7570 7575
Gly Gly Ala Ala Gly Ala Ala Cys Thr Gly Gly Ala Thr Thr Thr
7580 7585 7590
Cys Cys Thr Gly Cys Cys Ala Cys Cys Ala Gly Thr Thr Gly Gly
7595 7600 7605
Ala Cys Gly Ala Gly Thr Gly Gly Cys Thr Gly Thr Thr Gly Ala
7610 7615 7620
Thr Gly Thr Gly Ala Thr Gly Ala Ala Ala Gly Thr Ala Gly Ala
7625 7630 7635
Ala Ala Thr Cys Cys Cys Gly Cys Cys Gly Gly Cys Gly Ala Ala
7640 7645 7650
Cys Cys Gly Ala Gly Cys Ala Cys Thr Cys Gly Thr Gly Cys Thr
7655 7660 7665
Gly Ala Thr Gly Cys Thr Thr Gly Thr Ala Ala Ala Ala Gly Cys
7670 7675 7680
Gly Thr Cys Cys Gly Cys Ala Gly Thr Ala Cys Thr Cys Gly Cys
7685 7690 7695
Ala Gly Cys Gly Cys Thr Gly Cys Ala Cys Gly Gly Gly Cys Thr
7700 7705 7710
Gly Thr Ala Cys Cys Thr Cys Ala Thr Cys Cys Ala Cys Gly Ala
7715 7720 7725
Gly Ala Thr Ala Cys Ala Cys Ala Gly Cys Gly Cys Gly Thr Cys
7730 7735 7740
Cys Cys Thr Thr Gly Ala Gly Gly Ala Gly Gly Ala Ala Cys Thr
7745 7750 7755
Thr Cys Ala Gly Gly Ala Gly Thr Gly Gly Cys Gly Gly Cys Cys
7760 7765 7770
Cys Thr Gly Gly Cys Thr Gly Gly Thr Gly Gly Thr Thr Thr Thr
7775 7780 7785
Cys Ala Thr Gly Thr Thr Cys Gly Cys Cys Thr Gly Cys Gly Thr
7790 7795 7800
Gly Gly Gly Ala Cys Thr Cys Ala Cys Cys Cys Thr Gly Gly Gly
7805 7810 7815
Gly Cys Thr Cys Cys Thr Cys Gly Ala Gly Gly Ala Cys Gly Gly
7820 7825 7830
Ala Gly Ala Gly Gly Cys Thr Gly Ala Cys Gly Ala Gly Cys Cys
7835 7840 7845
Cys Gly Cys Gly Cys Gly Gly Gly Ala Gly Cys Cys Ala Gly Gly
7850 7855 7860
Thr Cys Cys Ala Gly Ala Thr Cys Thr Cys Gly Gly Cys Gly Cys
7865 7870 7875
Gly Gly Cys Gly Gly Gly Gly Gly Cys Gly Gly Ala Gly Ala Gly
7880 7885 7890
Cys Gly Ala Ala Gly Ala Cys Gly Ala Gly Gly Gly Cys Gly Cys
7895 7900 7905
Gly Cys Ala Gly Thr Thr Gly Gly Gly Ala Gly Cys Thr Gly Thr
7910 7915 7920
Cys Cys Ala Thr Gly Gly Thr Gly Thr Cys Gly Cys Gly Gly Ala
7925 7930 7935
Gly Ala Thr Cys Cys Ala Gly Gly Thr Cys Cys Gly Gly Gly Gly
7940 7945 7950
Gly Cys Ala Gly Gly Gly Thr Thr Cys Thr Gly Ala Gly Gly Thr
7955 7960 7965
Thr Gly Ala Cys Cys Thr Cys Gly Thr Ala Gly Ala Gly Gly Cys
7970 7975 7980
Gly Gly Gly Thr Gly Ala Gly Gly Gly Cys Gly Thr Gly Cys Thr
7985 7990 7995
Thr Gly Ala Gly Ala Thr Gly Cys Ala Gly Ala Thr Gly Gly Thr
8000 8005 8010
Ala Cys Thr Thr Gly Ala Thr Thr Thr Cys Thr Ala Cys Gly Gly
8015 8020 8025
Gly Thr Gly Ala Gly Thr Thr Gly Gly Thr Gly Gly Thr Cys Gly
8030 8035 8040
Thr Gly Thr Cys Cys Ala Cys Gly Cys Ala Thr Thr Gly Cys Ala
8045 8050 8055
Thr Gly Ala Gly Cys Cys Cys Gly Thr Ala Gly Cys Thr Gly Cys
8060 8065 8070
Gly Cys Gly Gly Gly Gly Cys Cys Ala Cys Gly Ala Cys Cys Gly
8075 8080 8085
Thr Gly Cys Cys Gly Cys Gly Gly Thr Gly Cys Gly Cys Thr Thr
8090 8095 8100
Thr Thr Ala Gly Ala Ala Gly Cys Gly Gly Thr Gly Thr Cys Gly
8105 8110 8115
Cys Gly Gly Ala Cys Gly Cys Gly Cys Thr Cys Cys Cys Gly Gly
8120 8125 8130
Cys Gly Gly Cys Ala Gly Cys Gly Gly Cys Gly Gly Thr Thr Cys
8135 8140 8145
Cys Gly Gly Cys Cys Cys Cys Gly Cys Gly Gly Gly Cys Ala Gly
8150 8155 8160
Gly Gly Gly Cys Gly Gly Cys Ala Gly Ala Gly Gly Cys Ala Cys
8165 8170 8175
Gly Thr Cys Gly Gly Cys Gly Thr Gly Gly Cys Gly Cys Thr Cys
8180 8185 8190
Gly Gly Gly Cys Ala Gly Gly Thr Cys Cys Cys Gly Gly Thr Gly
8195 8200 8205
Cys Thr Gly Cys Gly Cys Cys Cys Thr Gly Ala Gly Ala Gly Cys
8210 8215 8220
Gly Cys Thr Gly Gly Cys Gly Thr Gly Cys Gly Cys Gly Ala Cys
8225 8230 8235
Gly Ala Cys Gly Cys Gly Gly Cys Gly Gly Thr Thr Gly Ala Cys
8240 8245 8250
Ala Thr Cys Cys Thr Gly Gly Ala Thr Cys Thr Gly Cys Cys Gly
8255 8260 8265
Cys Cys Thr Cys Thr Gly Cys Gly Thr Gly Ala Ala Gly Ala Cys
8270 8275 8280
Cys Ala Cys Gly Gly Gly Cys Cys Cys Cys Gly Thr Gly Ala Cys
8285 8290 8295
Thr Thr Thr Gly Ala Ala Cys Cys Thr Gly Ala Ala Ala Gly Ala
8300 8305 8310
Cys Ala Gly Thr Thr Cys Ala Ala Cys Ala Gly Ala Ala Thr Cys
8315 8320 8325
Ala Ala Thr Cys Thr Cys Thr Gly Cys Gly Thr Cys Ala Thr Thr
8330 8335 8340
Gly Ala Cys Gly Gly Cys Gly Gly Cys Cys Thr Gly Ala Cys Gly
8345 8350 8355
Cys Ala Gly Gly Ala Thr Cys Thr Cys Thr Thr Gly Cys Ala Cys
8360 8365 8370
Gly Thr Cys Gly Cys Cys Cys Gly Ala Gly Thr Thr Gly Thr Cys
8375 8380 8385
Cys Thr Gly Gly Thr Ala Gly Gly Cys Gly Ala Thr Cys Thr Cys
8390 8395 8400
Gly Gly Ala Cys Ala Thr Gly Ala Ala Cys Thr Gly Thr Thr Cys
8405 8410 8415
Gly Ala Thr Cys Thr Cys Cys Thr Cys Cys Thr Cys Cys Thr Gly
8420 8425 8430
Gly Ala Gly Ala Thr Cys Gly Cys Cys Gly Cys Gly Gly Cys Cys
8435 8440 8445
Cys Gly Cys Gly Cys Gly Cys Thr Cys Cys Ala Cys Gly Gly Thr
8450 8455 8460
Gly Gly Cys Gly Gly Cys Gly Ala Gly Gly Thr Cys Ala Thr Thr
8465 8470 8475
Gly Gly Ala Gly Ala Thr Gly Cys Gly Ala Cys Cys Cys Ala Thr
8480 8485 8490
Gly Ala Gly Cys Thr Gly Cys Gly Ala Gly Ala Ala Gly Gly Cys
8495 8500 8505
Gly Cys Cys Cys Ala Gly Gly Cys Cys Gly Cys Thr Cys Thr Cys
8510 8515 8520
Gly Thr Thr Cys Cys Ala Gly Ala Cys Gly Cys Gly Gly Cys Thr
8525 8530 8535
Gly Thr Ala Gly Ala Cys Cys Ala Cys Gly Thr Cys Cys Cys Cys
8540 8545 8550
Gly Thr Cys Gly Gly Cys Gly Thr Cys Gly Cys Gly Cys Gly Cys
8555 8560 8565
Gly Cys Gly Cys Ala Thr Gly Ala Cys Cys Ala Cys Cys Thr Gly
8570 8575 8580
Cys Gly Cys Gly Ala Gly Gly Thr Thr Gly Ala Gly Cys Thr Cys
8585 8590 8595
Cys Ala Cys Gly Thr Gly Cys Cys Gly Cys Gly Cys Ala Ala Ala
8600 8605 8610
Gly Ala Cys Gly Gly Cys Gly Thr Ala Gly Thr Thr Gly Cys Gly
8615 8620 8625
Cys Ala Gly Gly Cys Gly Cys Thr Gly Gly Ala Ala Gly Ala Gly
8630 8635 8640
Gly Thr Ala Gly Thr Thr Gly Ala Gly Gly Gly Thr Gly Gly Thr
8645 8650 8655
Gly Gly Cys Gly Ala Thr Gly Thr Gly Cys Thr Cys Gly Gly Thr
8660 8665 8670
Gly Ala Cys Gly Ala Ala Gly Ala Ala Gly Thr Ala Cys Ala Thr
8675 8680 8685
Gly Ala Thr Cys Cys Ala Gly Cys Gly Gly Cys Gly Cys Ala Gly
8690 8695 8700
Gly Gly Gly Cys Ala Thr Cys Thr Cys Gly Cys Thr Gly Ala Thr
8705 8710 8715
Gly Thr Cys Gly Cys Cys Gly Ala Thr Gly Gly Cys Thr Thr Cys
8720 8725 8730
Cys Ala Gly Cys Cys Thr Thr Thr Cys Cys Ala Thr Gly Gly Cys
8735 8740 8745
Cys Thr Cys Gly Thr Ala Gly Ala Ala Gly Thr Cys Cys Ala Cys
8750 8755 8760
Gly Gly Cys Gly Ala Ala Gly Thr Thr Gly Ala Ala Ala Ala Ala
8765 8770 8775
Cys Thr Gly Gly Gly Cys Gly Thr Thr Gly Cys Gly Gly Gly Cys
8780 8785 8790
Cys Gly Ala Gly Ala Cys Cys Gly Thr Gly Ala Gly Cys Thr Cys
8795 8800 8805
Gly Thr Cys Thr Thr Cys Cys Ala Gly Gly Ala Gly Cys Cys Gly
8810 8815 8820
Gly Ala Thr Gly Ala Gly Thr Thr Cys Gly Gly Cys Gly Ala Thr
8825 8830 8835
Gly Gly Thr Gly Gly Cys Gly Cys Gly Cys Ala Cys Cys Thr Cys
8840 8845 8850
Gly Cys Gly Cys Thr Cys Gly Ala Ala Ala Thr Cys Cys Cys Cys
8855 8860 8865
Gly Gly Gly Gly Gly Cys Cys Thr Cys Cys Thr Cys Cys Thr Cys
8870 8875 8880
Thr Thr Cys Cys Thr Cys Thr Thr Cys Thr Thr Cys Cys Ala Thr
8885 8890 8895
Gly Ala Cys Gly Ala Cys Cys Thr Cys Thr Thr Cys Thr Thr Cys
8900 8905 8910
Thr Ala Thr Thr Thr Cys Thr Thr Cys Cys Thr Cys Thr Gly Gly
8915 8920 8925
Gly Gly Gly Cys Gly Gly Thr Gly Gly Thr Gly Gly Thr Gly Gly
8930 8935 8940
Cys Gly Gly Gly Gly Gly Cys Cys Gly Ala Cys Gly Ala Cys Gly
8945 8950 8955
Ala Cys Gly Gly Cys Gly Ala Cys Gly Cys Ala Cys Cys Gly Gly
8960 8965 8970
Gly Ala Gly Ala Cys Gly Gly Thr Cys Gly Ala Cys Gly Ala Ala
8975 8980 8985
Gly Cys Gly Cys Thr Cys Gly Ala Thr Cys Ala Thr Cys Thr Cys
8990 8995 9000
Cys Cys Cys Gly Cys Gly Gly Cys Gly Gly Cys Gly Ala Cys Gly
9005 9010 9015
Cys Ala Thr Gly Gly Thr Thr Thr Cys Gly Gly Thr Gly Ala Cys
9020 9025 9030
Gly Gly Cys Gly Cys Gly Ala Cys Cys Cys Cys Gly Thr Thr Cys
9035 9040 9045
Gly Cys Gly Ala Gly Gly Ala Cys Gly Cys Ala Gly Cys Gly Thr
9050 9055 9060
Gly Ala Ala Gly Ala Cys Gly Cys Cys Gly Cys Cys Gly Gly Thr
9065 9070 9075
Cys Ala Thr Cys Thr Cys Cys Cys Gly Gly Thr Ala Ala Thr Gly
9080 9085 9090
Gly Gly Gly Cys Gly Gly Gly Thr Cys Cys Cys Cys Ala Thr Thr
9095 9100 9105
Gly Gly Gly Cys Ala Gly Cys Gly Ala Thr Ala Gly Gly Gly Cys
9110 9115 9120
Gly Cys Thr Gly Ala Cys Gly Ala Thr Gly Cys Ala Thr Cys Thr
9125 9130 9135
Thr Ala Thr Cys Ala Ala Thr Thr Gly Cys Gly Gly Thr Gly Thr
9140 9145 9150
Ala Gly Gly Gly Gly Ala Cys Gly Thr Gly Ala Gly Cys Gly Cys
9155 9160 9165
Gly Thr Cys Gly Ala Gly Ala Thr Cys Gly Ala Cys Cys Gly Gly
9170 9175 9180
Ala Thr Cys Gly Gly Ala Gly Ala Ala Thr Cys Thr Thr Thr Cys
9185 9190 9195
Gly Ala Gly Gly Ala Ala Ala Gly Cys Gly Thr Cys Thr Ala Gly
9200 9205 9210
Cys Cys Ala Ala Thr Cys Gly Cys Ala Gly Thr Cys Gly Cys Ala
9215 9220 9225
Ala Gly Gly Thr Ala Ala Gly Cys Thr Cys Ala Ala Ala Cys Ala
9230 9235 9240
Cys Gly Thr Ala Gly Cys Ala Gly Cys Cys Cys Thr Gly Cys Gly
9245 9250 9255
Gly Ala Cys Gly Cys Thr Gly Thr Thr Ala Gly Ala Ala Thr Thr
9260 9265 9270
Gly Cys Gly Gly Thr Thr Gly Cys Thr Gly Ala Thr Gly Ala Thr
9275 9280 9285
Gly Thr Ala Ala Thr Thr Gly Ala Ala Gly Thr Ala Gly Gly Cys
9290 9295 9300
Gly Thr Thr Thr Thr Thr Gly Ala Gly Gly Cys Gly Gly Cys Gly
9305 9310 9315
Gly Ala Thr Gly Gly Thr Gly Gly Cys Gly Ala Gly Gly Ala Gly
9320 9325 9330
Gly Ala Cys Cys Ala Gly Gly Thr Cys Cys Thr Thr Gly Gly Gly
9335 9340 9345
Thr Cys Cys Ala Gly Cys Thr Thr Gly Cys Thr Gly Gly Ala Thr
9350 9355 9360
Gly Cys Gly Gly Ala Gly Cys Cys Gly Cys Thr Cys Gly Gly Cys
9365 9370 9375
Cys Ala Thr Gly Cys Cys Cys Cys Ala Gly Gly Cys Cys Thr Gly
9380 9385 9390
Gly Cys Cys Cys Thr Gly Ala Cys Ala Cys Cys Gly Gly Cys Thr
9395 9400 9405
Cys Ala Gly Gly Thr Thr Cys Thr Thr Gly Thr Ala Gly Thr Ala
9410 9415 9420
Gly Thr Cys Ala Thr Gly Cys Ala Thr Gly Ala Gly Cys Cys Thr
9425 9430 9435
Cys Thr Cys Ala Ala Thr Gly Thr Cys Ala Thr Cys Ala Cys Thr
9440 9445 9450
Gly Gly Cys Thr Gly Ala Gly Gly Cys Gly Gly Ala Gly Thr Cys
9455 9460 9465
Thr Thr Cys Cys Ala Thr Gly Cys Gly Gly Gly Thr Gly Ala Cys
9470 9475 9480
Cys Cys Cys Gly Ala Cys Gly Cys Cys Cys Cys Thr Gly Ala Gly
9485 9490 9495
Cys Gly Gly Cys Thr Gly Cys Ala Cys Gly Ala Gly Cys Gly Cys
9500 9505 9510
Cys Ala Gly Gly Thr Cys Gly Gly Cys Gly Ala Cys Gly Ala Cys
9515 9520 9525
Gly Cys Gly Cys Thr Cys Gly Gly Cys Gly Ala Gly Gly Ala Thr
9530 9535 9540
Gly Gly Cys Cys Thr Gly Thr Thr Gly Cys Ala Cys Gly Cys Gly
9545 9550 9555
Gly Gly Thr Gly Ala Gly Gly Gly Thr Gly Thr Cys Cys Thr Gly
9560 9565 9570
Gly Ala Ala Gly Thr Cys Gly Thr Cys Cys Ala Thr Gly Thr Cys
9575 9580 9585
Gly Ala Cys Gly Ala Ala Gly Cys Gly Gly Thr Gly Ala Thr Ala
9590 9595 9600
Gly Gly Cys Cys Cys Cys Gly Gly Thr Gly Thr Thr Gly Ala Thr
9605 9610 9615
Gly Gly Thr Gly Thr Ala Gly Gly Thr Gly Cys Ala Gly Thr Thr
9620 9625 9630
Gly Gly Cys Cys Ala Thr Gly Ala Gly Cys Gly Ala Cys Cys Ala
9635 9640 9645
Gly Thr Thr Gly Ala Cys Gly Gly Thr Cys Thr Gly Cys Ala Gly
9650 9655 9660
Gly Cys Cys Thr Gly Gly Cys Thr Gly Cys Ala Cys Gly Ala Cys
9665 9670 9675
Cys Thr Cys Gly Gly Ala Gly Thr Ala Cys Cys Thr Gly Ala Gly
9680 9685 9690
Cys Cys Gly Cys Gly Ala Gly Ala Ala Gly Gly Cys Gly Cys Gly
9695 9700 9705
Cys Gly Ala Gly Thr Cys Gly Ala Ala Gly Ala Cys Gly Thr Ala
9710 9715 9720
Gly Thr Cys Gly Thr Thr Gly Cys Ala Gly Gly Thr Gly Cys Gly
9725 9730 9735
Cys Ala Cys Gly Ala Gly Gly Thr Ala Cys Thr Gly Gly Thr Ala
9740 9745 9750
Thr Cys Cys Gly Ala Cys Thr Ala Gly Gly Ala Ala Gly Thr Gly
9755 9760 9765
Cys Gly Gly Cys Gly Gly Cys Gly Gly Cys Thr Gly Gly Cys Gly
9770 9775 9780
Gly Thr Ala Gly Ala Gly Cys Gly Gly Cys Cys Ala Gly Cys Gly
9785 9790 9795
Cys Thr Gly Gly Gly Thr Gly Gly Cys Cys Gly Gly Cys Gly Cys
9800 9805 9810
Gly Cys Cys Cys Gly Gly Gly Gly Cys Cys Ala Gly Gly Thr Cys
9815 9820 9825
Cys Thr Cys Gly Ala Gly Cys Ala Thr Gly Ala Gly Gly Cys Gly
9830 9835 9840
Gly Thr Gly Gly Thr Ala Gly Cys Cys Gly Thr Ala Gly Ala Gly
9845 9850 9855
Gly Thr Ala Gly Cys Gly Gly Gly Ala Cys Ala Thr Cys Cys Ala
9860 9865 9870
Gly Gly Thr Gly Ala Thr Gly Cys Cys Gly Gly Cys Gly Gly Cys
9875 9880 9885
Gly Gly Thr Gly Gly Thr Gly Gly Ala Gly Gly Cys Gly Cys Gly
9890 9895 9900
Cys Gly Gly Gly Ala Ala Cys Thr Cys Gly Cys Gly Gly Ala Cys
9905 9910 9915
Gly Cys Gly Gly Thr Thr Cys Cys Ala Gly Ala Thr Gly Thr Thr
9920 9925 9930
Gly Cys Gly Cys Ala Gly Cys Gly Gly Cys Ala Gly Gly Ala Ala
9935 9940 9945
Ala Thr Ala Gly Thr Cys Cys Ala Thr Gly Gly Thr Cys Gly Gly
9950 9955 9960
Cys Ala Cys Gly Gly Thr Cys Thr Gly Gly Cys Cys Gly Gly Thr
9965 9970 9975
Gly Ala Gly Ala Cys Gly Cys Gly Cys Gly Cys Ala Gly Thr Cys
9980 9985 9990
Ala Thr Thr Gly Ala Cys Gly Cys Thr Cys Thr Ala Gly Ala Gly
9995 10000 10005
Gly Cys Ala Ala Ala Ala Ala Cys Gly Ala Ala Ala Gly Cys Gly
10010 10015 10020
Gly Thr Thr Gly Ala Gly Cys Gly Gly Gly Cys Thr Cys Thr Thr
10025 10030 10035
Cys Cys Thr Cys Cys Gly Thr Ala Gly Cys Cys Thr Gly Gly Cys
10040 10045 10050
Gly Gly Ala Ala Cys Gly Cys Ala Ala Ala Cys Gly Gly Gly Thr
10055 10060 10065
Thr Ala Gly Gly Cys Cys Gly Cys Gly Thr Gly Thr Gly Thr Ala
10070 10075 10080
Cys Cys Cys Cys Gly Gly Thr Thr Cys Gly Ala Gly Thr Cys Cys
10085 10090 10095
Cys Cys Thr Cys Gly Ala Ala Thr Cys Ala Gly Gly Cys Thr Gly
10100 10105 10110
Gly Ala Gly Cys Cys Gly Cys Gly Ala Cys Thr Ala Ala Cys Gly
10115 10120 10125
Thr Gly Gly Thr Ala Thr Thr Gly Gly Cys Ala Cys Thr Cys Cys
10130 10135 10140
Cys Gly Thr Cys Thr Cys Gly Ala Cys Cys Cys Gly Ala Gly Cys
10145 10150 10155
Cys Cys Gly Ala Thr Ala Gly Cys Cys Gly Cys Cys Ala Gly Gly
10160 10165 10170
Ala Thr Ala Cys Gly Gly Cys Gly Gly Ala Gly Ala Gly Cys Cys
10175 10180 10185
Cys Thr Thr Thr Thr Thr Gly Cys Cys Gly Gly Cys Cys Gly Ala
10190 10195 10200
Gly Thr Gly Gly Gly Gly Thr Cys Gly Cys Thr Ala Gly Ala Cys
10205 10210 10215
Thr Thr Gly Ala Ala Ala Gly Cys Gly Ala Cys Cys Gly Ala Ala
10220 10225 10230
Ala Ala Cys Cys Cys Thr Gly Cys Cys Gly Gly Gly Thr Ala Gly
10235 10240 10245
Thr Gly Gly Cys Thr Cys Gly Cys Gly Cys Cys Cys Gly Thr Ala
10250 10255 10260
Gly Thr Cys Thr Gly Gly Ala Gly Ala Ala Gly Cys Ala Thr Cys
10265 10270 10275
Gly Cys Cys Ala Gly Gly Gly Thr Thr Gly Ala Gly Thr Cys Gly
10280 10285 10290
Cys Gly Gly Cys Ala Gly Ala Ala Cys Cys Cys Gly Gly Thr Thr
10295 10300 10305
Cys Gly Ala Gly Gly Ala Cys Gly Gly Cys Cys Gly Cys Gly Gly
10310 10315 10320
Cys Gly Ala Gly Cys Gly Gly Gly Ala Cys Thr Thr Gly Gly Thr
10325 10330 10335
Cys Ala Cys Cys Cys Cys Gly Cys Cys Gly Ala Thr Ala Thr Ala
10340 10345 10350
Ala Ala Gly Ala Cys Cys Cys Ala Cys Ala Gly Cys Cys Ala Gly
10355 10360 10365
Cys Cys Gly Ala Cys Thr Thr Cys Thr Cys Cys Ala Gly Thr Thr
10370 10375 10380
Ala Cys Gly Gly Gly Ala Gly Cys Gly Ala Gly Cys Cys Cys Cys
10385 10390 10395
Cys Thr Thr Thr Thr Thr Thr Cys Thr Thr Thr Thr Thr Gly Cys
10400 10405 10410
Cys Ala Gly Ala Thr Gly Cys Ala Thr Cys Cys Cys Gly Thr Cys
10415 10420 10425
Cys Thr Gly Cys Gly Cys Cys Ala Ala Ala Thr Gly Cys Gly Thr
10430 10435 10440
Cys Cys Cys Ala Cys Cys Cys Cys Cys Cys Cys Gly Gly Cys Gly
10445 10450 10455
Ala Cys Cys Ala Cys Cys Gly Cys Gly Ala Cys Cys Gly Cys Gly
10460 10465 10470
Gly Cys Cys Gly Thr Ala Gly Cys Ala Gly Gly Cys Gly Cys Cys
10475 10480 10485
Gly Gly Cys Gly Cys Thr Ala Gly Cys Cys Ala Gly Cys Cys Ala
10490 10495 10500
Cys Cys Ala Cys Ala Gly Ala Cys Ala Gly Ala Gly Ala Thr Gly
10505 10510 10515
Gly Ala Cys Thr Thr Gly Gly Ala Ala Gly Ala Gly Gly Gly Cys
10520 10525 10530
Gly Ala Ala Gly Gly Gly Cys Thr Gly Gly Cys Ala Ala Gly Ala
10535 10540 10545
Cys Thr Gly Gly Gly Gly Gly Cys Gly Cys Cys Gly Thr Cys Cys
10550 10555 10560
Cys Cys Gly Gly Ala Gly Cys Gly Ala Cys Ala Thr Cys Cys Cys
10565 10570 10575
Cys Gly Cys Gly Thr Gly Cys Ala Gly Cys Thr Gly Cys Ala Gly
10580 10585 10590
Ala Ala Gly Gly Ala Cys Gly Thr Gly Cys Gly Cys Cys Cys Gly
10595 10600 10605
Gly Cys Gly Thr Ala Cys Gly Thr Gly Cys Cys Thr Ala Cys Gly
10610 10615 10620
Cys Ala Gly Ala Ala Cys Cys Thr Gly Thr Thr Cys Ala Gly Gly
10625 10630 10635
Gly Ala Cys Cys Gly Cys Ala Gly Cys Gly Gly Gly Gly Ala Gly
10640 10645 10650
Gly Ala Gly Cys Cys Cys Gly Ala Gly Gly Ala Gly Ala Thr Gly
10655 10660 10665
Cys Gly Cys Gly Ala Cys Thr Gly Cys Cys Gly Gly Thr Thr Thr
10670 10675 10680
Cys Gly Gly Gly Cys Gly Gly Gly Cys Ala Gly Gly Gly Ala Gly
10685 10690 10695
Cys Thr Gly Cys Gly Cys Gly Ala Gly Gly Gly Cys Cys Thr Gly
10700 10705 10710
Gly Ala Cys Cys Gly Cys Cys Ala Gly Cys Gly Cys Gly Thr Gly
10715 10720 10725
Cys Thr Gly Cys Gly Cys Gly Ala Cys Gly Ala Gly Gly Ala Thr
10730 10735 10740
Thr Thr Cys Gly Ala Gly Cys Cys Gly Ala Ala Cys Gly Ala Gly
10745 10750 10755
Cys Ala Gly Ala Cys Gly Gly Gly Gly Ala Thr Cys Ala Gly Cys
10760 10765 10770
Cys Cys Cys Gly Cys Ala Cys Gly Cys Gly Cys Gly Cys Ala Cys
10775 10780 10785
Gly Thr Gly Gly Cys Gly Gly Cys Ala Gly Cys Cys Ala Ala Cys
10790 10795 10800
Cys Thr Gly Gly Thr Gly Ala Cys Gly Gly Cys Cys Thr Ala Cys
10805 10810 10815
Gly Ala Gly Cys Ala Gly Ala Cys Gly Gly Thr Gly Ala Ala Gly
10820 10825 10830
Cys Ala Gly Gly Ala Gly Cys Gly Cys Ala Ala Cys Thr Thr Cys
10835 10840 10845
Cys Ala Ala Ala Ala Gly Ala Gly Thr Thr Thr Cys Ala Ala Cys
10850 10855 10860
Ala Ala Cys Cys Ala Cys Gly Thr Gly Cys Gly Cys Ala Cys Cys
10865 10870 10875
Cys Thr Gly Ala Thr Cys Gly Cys Gly Cys Gly Cys Gly Ala Gly
10880 10885 10890
Gly Ala Gly Gly Thr Gly Gly Cys Cys Cys Thr Gly Gly Gly Cys
10895 10900 10905
Cys Thr Gly Ala Thr Gly Cys Ala Cys Cys Thr Gly Thr Gly Gly
10910 10915 10920
Gly Ala Cys Cys Thr Gly Gly Cys Gly Gly Ala Gly Gly Cys Cys
10925 10930 10935
Ala Thr Cys Gly Thr Gly Cys Ala Gly Ala Ala Cys Cys Cys Gly
10940 10945 10950
Gly Ala Cys Ala Gly Cys Ala Ala Gly Cys Cys Thr Cys Thr Gly
10955 10960 10965
Ala Cys Gly Gly Cys Gly Cys Ala Gly Cys Thr Gly Thr Thr Cys
10970 10975 10980
Cys Thr Gly Gly Thr Gly Gly Thr Gly Cys Ala Gly Cys Ala Cys
10985 10990 10995
Ala Gly Cys Ala Gly Gly Gly Ala Cys Ala Ala Cys Gly Ala Gly
11000 11005 11010
Gly Cys Gly Thr Thr Cys Ala Gly Gly Gly Ala Gly Gly Cys Gly
11015 11020 11025
Cys Thr Gly Cys Thr Gly Ala Ala Cys Ala Thr Cys Gly Cys Cys
11030 11035 11040
Gly Ala Gly Cys Cys Cys Gly Ala Gly Gly Gly Thr Cys Gly Cys
11045 11050 11055
Thr Gly Gly Cys Thr Gly Cys Thr Gly Gly Ala Gly Cys Thr Gly
11060 11065 11070
Ala Thr Thr Ala Ala Cys Ala Thr Cys Thr Thr Gly Cys Ala Gly
11075 11080 11085
Ala Gly Cys Ala Thr Cys Gly Thr Ala Gly Thr Gly Cys Ala Gly
11090 11095 11100
Gly Ala Gly Cys Gly Cys Ala Gly Cys Cys Thr Gly Ala Gly Cys
11105 11110 11115
Cys Thr Gly Gly Cys Cys Gly Ala Gly Ala Ala Gly Gly Thr Gly
11120 11125 11130
Gly Cys Gly Gly Cys Gly Ala Thr Cys Ala Ala Cys Thr Ala Cys
11135 11140 11145
Thr Cys Gly Gly Thr Gly Cys Thr Gly Ala Gly Cys Cys Thr Gly
11150 11155 11160
Gly Gly Cys Ala Ala Gly Thr Thr Thr Thr Ala Cys Gly Cys Gly
11165 11170 11175
Cys Gly Cys Ala Ala Gly Ala Thr Thr Thr Ala Cys Ala Ala Gly
11180 11185 11190
Ala Cys Gly Cys Cys Gly Thr Ala Cys Gly Thr Gly Cys Cys Cys
11195 11200 11205
Ala Thr Ala Gly Ala Cys Ala Ala Gly Gly Ala Gly Gly Thr Gly
11210 11215 11220
Ala Ala Gly Ala Thr Ala Gly Ala Cys Ala Gly Cys Thr Thr Thr
11225 11230 11235
Thr Ala Cys Ala Thr Gly Cys Gly Cys Ala Thr Gly Gly Cys Gly
11240 11245 11250
Cys Thr Cys Ala Ala Gly Gly Thr Gly Cys Thr Gly Ala Cys Gly
11255 11260 11265
Cys Thr Gly Ala Gly Cys Gly Ala Cys Gly Ala Cys Cys Thr Gly
11270 11275 11280
Gly Gly Cys Gly Thr Gly Thr Ala Cys Cys Gly Cys Ala Ala Cys
11285 11290 11295
Gly Ala Cys Cys Gly Cys Ala Thr Cys Cys Ala Cys Ala Ala Gly
11300 11305 11310
Gly Cys Cys Gly Thr Gly Ala Gly Cys Ala Cys Gly Ala Gly Cys
11315 11320 11325
Cys Gly Gly Cys Gly Gly Cys Gly Cys Gly Ala Gly Cys Thr Gly
11330 11335 11340
Ala Gly Cys Gly Ala Cys Cys Gly Cys Gly Ala Gly Cys Thr Gly
11345 11350 11355
Ala Thr Gly Cys Thr Gly Ala Gly Thr Cys Thr Gly Cys Gly Cys
11360 11365 11370
Cys Gly Gly Gly Cys Gly Cys Thr Gly Gly Thr Ala Gly Gly Gly
11375 11380 11385
Gly Gly Cys Gly Cys Cys Gly Cys Cys Gly Gly Cys Gly Gly Cys
11390 11395 11400
Gly Ala Gly Gly Ala Gly Thr Cys Cys Thr Ala Cys Thr Thr Cys
11405 11410 11415
Gly Ala Cys Ala Thr Gly Gly Gly Thr Gly Cys Gly Gly Ala Cys
11420 11425 11430
Cys Thr Gly Cys Ala Thr Thr Gly Gly Cys Ala Gly Cys Cys Gly
11435 11440 11445
Ala Gly Cys Cys Gly Gly Cys Gly Cys Gly Cys Cys Thr Thr Gly
11450 11455 11460
Gly Ala Gly Gly Cys Cys Gly Cys Cys Thr Ala Cys Gly Gly Thr
11465 11470 11475
Thr Cys Ala Gly Ala Gly Gly Ala Cys Thr Thr Gly Gly Ala Thr
11480 11485 11490
Gly Ala Gly Gly Ala Ala Gly Ala Gly Gly Ala Ala Gly Ala Gly
11495 11500 11505
Gly Ala Gly Gly Ala Gly Gly Ala Thr Gly Cys Ala Cys Cys Cys
11510 11515 11520
Gly Cys Thr Gly Cys Gly Gly Gly Gly Thr Ala Cys Thr Gly Ala
11525 11530 11535
Cys Gly Cys Cys Thr Cys Cys Gly Thr Gly Ala Thr Gly Thr Gly
11540 11545 11550
Thr Thr Thr Thr Thr Ala Gly Ala Thr Gly Thr Cys Cys Cys Ala
11555 11560 11565
Gly Cys Ala Ala Gly Cys Cys Cys Cys Gly Gly Ala Cys Cys Cys
11570 11575 11580
Cys Gly Cys Cys Ala Thr Ala Ala Gly Gly Gly Cys Gly Gly Cys
11585 11590 11595
Gly Cys Thr Gly Cys Ala Ala Ala Gly Cys Cys Ala Gly Cys Cys
11600 11605 11610
Gly Thr Cys Cys Gly Gly Thr Cys Thr Ala Gly Cys Ala Thr Cys
11615 11620 11625
Gly Gly Ala Cys Gly Ala Cys Thr Gly Gly Gly Ala Gly Gly Cys
11630 11635 11640
Cys Gly Cys Gly Ala Thr Gly Cys Ala Ala Cys Gly Cys Ala Thr
11645 11650 11655
Cys Ala Thr Gly Gly Cys Cys Cys Thr Gly Ala Cys Gly Ala Cys
11660 11665 11670
Cys Cys Gly Cys Ala Ala Cys Cys Cys Cys Gly Ala Gly Thr Cys
11675 11680 11685
Cys Thr Thr Thr Ala Gly Ala Cys Ala Ala Cys Ala Gly Cys Cys
11690 11695 11700
Gly Cys Ala Gly Gly Cys Cys Ala Ala Cys Ala Gly Ala Cys Thr
11705 11710 11715
Cys Thr Cys Gly Gly Cys Cys Ala Thr Thr Cys Thr Gly Gly Ala
11720 11725 11730
Gly Gly Cys Gly Gly Thr Gly Gly Thr Cys Cys Cys Cys Thr Cys
11735 11740 11745
Thr Cys Gly Gly Ala Cys Cys Ala Ala Cys Cys Cys Cys Ala Cys
11750 11755 11760
Gly Cys Ala Cys Gly Ala Gly Ala Ala Gly Gly Thr Gly Cys Thr
11765 11770 11775
Gly Gly Cys Gly Ala Thr Cys Gly Thr Gly Ala Ala Cys Gly Cys
11780 11785 11790
Gly Cys Thr Gly Gly Cys Gly Gly Ala Gly Ala Ala Cys Ala Ala
11795 11800 11805
Gly Gly Cys Cys Ala Thr Cys Cys Gly Thr Cys Cys Cys Gly Ala
11810 11815 11820
Cys Gly Ala Gly Gly Cys Cys Gly Gly Gly Cys Thr Gly Gly Thr
11825 11830 11835
Gly Thr Ala Cys Ala Ala Cys Gly Cys Cys Cys Thr Gly Cys Thr
11840 11845 11850
Gly Gly Ala Gly Cys Gly Cys Gly Thr Gly Gly Gly Cys Cys Gly
11855 11860 11865
Cys Thr Ala Cys Ala Ala Cys Ala Gly Cys Ala Cys Gly Ala Ala
11870 11875 11880
Cys Gly Thr Gly Cys Ala Gly Thr Cys Cys Ala Ala Cys Cys Thr
11885 11890 11895
Gly Gly Ala Thr Cys Gly Gly Cys Thr Gly Gly Thr Gly Ala Cys
11900 11905 11910
Gly Gly Ala Cys Gly Thr Gly Cys Gly Cys Gly Ala Gly Gly Cys
11915 11920 11925
Cys Gly Thr Gly Gly Cys Gly Cys Ala Gly Cys Gly Cys Gly Ala
11930 11935 11940
Gly Cys Gly Gly Thr Thr Cys Ala Ala Gly Ala Ala Cys Gly Ala
11945 11950 11955
Gly Gly Gly Cys Cys Thr Gly Gly Gly Cys Thr Cys Gly Cys Thr
11960 11965 11970
Gly Gly Thr Gly Gly Cys Gly Cys Thr Gly Ala Ala Cys Gly Cys
11975 11980 11985
Cys Thr Thr Cys Cys Thr Gly Gly Cys Gly Ala Cys Gly Cys Ala
11990 11995 12000
Gly Cys Cys Gly Gly Cys Gly Ala Ala Cys Gly Thr Gly Cys Cys
12005 12010 12015
Gly Cys Gly Cys Gly Gly Gly Cys Ala Gly Gly Ala Cys Gly Ala
12020 12025 12030
Thr Thr Ala Cys Ala Cys Cys Ala Ala Cys Thr Thr Thr Ala Thr
12035 12040 12045
Cys Ala Gly Cys Gly Cys Gly Cys Thr Gly Cys Gly Gly Cys Thr
12050 12055 12060
Gly Ala Thr Gly Gly Thr Gly Ala Cys Cys Gly Ala Gly Gly Thr
12065 12070 12075
Gly Cys Cys Cys Cys Ala Gly Ala Gly Cys Gly Ala Gly Gly Thr
12080 12085 12090
Gly Thr Ala Cys Cys Ala Gly Thr Cys Thr Gly Gly Cys Cys Cys
12095 12100 12105
Gly Gly Ala Cys Thr Ala Cys Thr Thr Thr Thr Thr Cys Cys Ala
12110 12115 12120
Gly Ala Cys Gly Ala Gly Cys Cys Gly Gly Cys Ala Gly Gly Gly
12125 12130 12135
Cys Thr Thr Gly Cys Ala Gly Ala Cys Gly Gly Thr Gly Ala Ala
12140 12145 12150
Cys Cys Thr Gly Ala Gly Cys Cys Ala Gly Gly Cys Thr Thr Thr
12155 12160 12165
Cys Ala Ala Gly Ala Ala Thr Cys Thr Gly Cys Gly Cys Gly Gly
12170 12175 12180
Gly Cys Thr Gly Thr Gly Gly Gly Gly Cys Gly Thr Gly Cys Ala
12185 12190 12195
Gly Gly Cys Gly Cys Cys Cys Gly Thr Gly Gly Gly Cys Gly Ala
12200 12205 12210
Cys Cys Gly Gly Thr Cys Ala Ala Cys Gly Gly Thr Gly Ala Gly
12215 12220 12225
Cys Ala Gly Cys Thr Thr Gly Cys Thr Gly Ala Cys Gly Cys Cys
12230 12235 12240
Cys Ala Ala Cys Thr Cys Gly Cys Gly Gly Cys Thr Gly Cys Thr
12245 12250 12255
Gly Cys Thr Gly Cys Thr Gly Cys Thr Gly Ala Thr Cys Gly Cys
12260 12265 12270
Gly Cys Cys Cys Thr Thr Cys Ala Cys Cys Gly Ala Cys Ala Gly
12275 12280 12285
Cys Gly Gly Cys Ala Gly Cys Gly Thr Gly Ala Ala Cys Cys Gly
12290 12295 12300
Cys Ala Ala Cys Thr Cys Gly Thr Ala Cys Cys Thr Gly Gly Gly
12305 12310 12315
Cys Cys Ala Thr Cys Thr Gly Cys Thr Gly Ala Cys Gly Cys Thr
12320 12325 12330
Gly Thr Ala Cys Cys Gly Cys Gly Ala Gly Gly Cys Cys Ala Thr
12335 12340 12345
Ala Gly Gly Cys Cys Ala Gly Gly Cys Gly Cys Ala Gly Gly Thr
12350 12355 12360
Gly Gly Ala Cys Gly Ala Gly Cys Ala Gly Ala Cys Cys Thr Thr
12365 12370 12375
Cys Cys Ala Gly Gly Ala Gly Ala Thr Cys Ala Cys Thr Ala Gly
12380 12385 12390
Cys Gly Thr Gly Ala Gly Cys Cys Gly Cys Gly Cys Gly Cys Thr
12395 12400 12405
Gly Gly Gly Gly Cys Ala Gly Ala Ala Cys Gly Ala Cys Ala Cys
12410 12415 12420
Cys Gly Ala Cys Ala Gly Thr Cys Thr Gly Ala Gly Gly Gly Cys
12425 12430 12435
Cys Ala Cys Cys Cys Thr Gly Ala Ala Cys Thr Thr Thr Thr Thr
12440 12445 12450
Gly Cys Thr Gly Ala Cys Cys Ala Ala Thr Ala Gly Ala Cys Ala
12455 12460 12465
Gly Cys Ala Gly Ala Ala Gly Ala Thr Cys Cys Cys Gly Gly Cys
12470 12475 12480
Gly Cys Ala Gly Thr Ala Cys Gly Cys Ala Cys Thr Gly Thr Cys
12485 12490 12495
Gly Gly Cys Cys Gly Ala Gly Gly Ala Gly Gly Ala Ala Ala Gly
12500 12505 12510
Gly Ala Thr Thr Cys Thr Gly Ala Gly Ala Thr Ala Thr Gly Thr
12515 12520 12525
Gly Cys Ala Gly Cys Ala Gly Ala Gly Cys Gly Thr Ala Gly Gly
12530 12535 12540
Gly Cys Thr Gly Thr Thr Cys Cys Thr Gly Ala Thr Gly Cys Ala
12545 12550 12555
Gly Gly Ala Gly Gly Gly Thr Gly Cys Cys Ala Cys Cys Cys Cys
12560 12565 12570
Cys Ala Gly Cys Gly Cys Cys Gly Cys Gly Cys Thr Gly Gly Ala
12575 12580 12585
Cys Ala Thr Gly Ala Cys Cys Gly Cys Gly Cys Gly Cys Ala Ala
12590 12595 12600
Cys Ala Thr Gly Gly Ala Ala Cys Cys Thr Ala Gly Cys Ala Thr
12605 12610 12615
Gly Thr Ala Cys Gly Cys Cys Gly Cys Cys Ala Ala Cys Cys Gly
12620 12625 12630
Gly Cys Cys Gly Thr Thr Cys Ala Thr Cys Ala Ala Thr Ala Ala
12635 12640 12645
Gly Cys Thr Gly Ala Thr Gly Gly Ala Cys Thr Ala Cys Thr Thr
12650 12655 12660
Gly Cys Ala Cys Cys Gly Cys Gly Cys Gly Gly Cys Gly Gly Cys
12665 12670 12675
Cys Ala Thr Gly Ala Ala Cys Ala Cys Gly Gly Ala Cys Thr Ala
12680 12685 12690
Cys Thr Thr Thr Ala Cys Cys Ala Ala Cys Gly Cys Cys Ala Thr
12695 12700 12705
Cys Cys Thr Gly Ala Ala Cys Cys Cys Gly Cys Ala Cys Thr Gly
12710 12715 12720
Gly Cys Thr Cys Cys Cys Gly Cys Cys Gly Cys Cys Gly Gly Gly
12725 12730 12735
Gly Thr Thr Cys Thr Ala Cys Ala Cys Gly Gly Gly Cys Gly Ala
12740 12745 12750
Gly Thr Ala Cys Gly Ala Cys Ala Thr Gly Cys Cys Cys Gly Ala
12755 12760 12765
Cys Cys Cys Cys Ala Ala Cys Gly Ala Cys Gly Gly Gly Thr Thr
12770 12775 12780
Cys Cys Thr Gly Thr Gly Gly Gly Ala Cys Gly Ala Cys Gly Thr
12785 12790 12795
Gly Gly Ala Cys Ala Gly Cys Gly Cys Gly Gly Thr Gly Thr Thr
12800 12805 12810
Cys Thr Cys Gly Cys Cys Gly Ala Cys Cys Thr Thr Thr Cys Ala
12815 12820 12825
Ala Ala Ala Gly Cys Gly Cys Cys Ala Gly Gly Ala Gly Gly Cys
12830 12835 12840
Gly Cys Cys Gly Cys Cys Gly Ala Gly Cys Gly Ala Gly Gly Gly
12845 12850 12855
Cys Gly Cys Gly Gly Thr Gly Gly Gly Gly Ala Gly Gly Ala Gly
12860 12865 12870
Cys Cys Cys Cys Thr Thr Thr Cys Cys Thr Ala Gly Cys Thr Thr
12875 12880 12885
Ala Gly Gly Gly Ala Gly Thr Thr Thr Gly Cys Ala Thr Ala Gly
12890 12895 12900
Cys Thr Thr Gly Cys Cys Gly Gly Gly Cys Thr Cys Gly Gly Thr
12905 12910 12915
Gly Ala Ala Cys Ala Gly Cys Gly Gly Cys Ala Gly Gly Gly Thr
12920 12925 12930
Gly Ala Gly Cys Cys Gly Gly Cys Cys Gly Cys Gly Cys Thr Thr
12935 12940 12945
Gly Cys Thr Gly Gly Gly Cys Gly Ala Gly Gly Ala Cys Gly Ala
12950 12955 12960
Gly Thr Ala Cys Cys Thr Gly Ala Ala Cys Gly Ala Cys Thr Cys
12965 12970 12975
Gly Cys Thr Gly Cys Thr Gly Cys Ala Gly Cys Cys Gly Cys Cys
12980 12985 12990
Gly Cys Gly Gly Gly Cys Cys Ala Ala Gly Ala Ala Cys Gly Cys
12995 13000 13005
Cys Ala Thr Gly Gly Cys Cys Ala Ala Thr Ala Ala Cys Gly Gly
13010 13015 13020
Gly Ala Thr Ala Gly Ala Gly Ala Gly Thr Cys Thr Gly Gly Thr
13025 13030 13035
Gly Gly Ala Cys Ala Ala Ala Cys Thr Gly Ala Ala Cys Cys Gly
13040 13045 13050
Cys Thr Gly Gly Ala Ala Gly Ala Cys Cys Thr Ala Cys Gly Cys
13055 13060 13065
Thr Cys Ala Gly Gly Ala Cys Cys Ala Thr Ala Gly Gly Gly Ala
13070 13075 13080
Cys Gly Cys Gly Cys Cys Cys Gly Cys Gly Cys Cys Gly Cys Gly
13085 13090 13095
Gly Cys Gly Ala Cys Ala Gly Cys Gly Cys Cys Ala Cys Gly Ala
13100 13105 13110
Cys Cys Gly Gly Cys Ala Gly Cys Gly Gly Gly Gly Cys Cys Thr
13115 13120 13125
Gly Gly Thr Gly Thr Gly Gly Gly Ala Cys Gly Ala Cys Gly Ala
13130 13135 13140
Gly Gly Ala Cys Thr Cys Gly Gly Cys Cys Gly Ala Cys Gly Ala
13145 13150 13155
Thr Ala Gly Cys Ala Gly Cys Gly Thr Gly Thr Thr Gly Gly Ala
13160 13165 13170
Cys Thr Thr Gly Gly Gly Cys Gly Gly Gly Ala Gly Cys Gly Gly
13175 13180 13185
Thr Gly Gly Gly Gly Thr Cys Ala Ala Cys Cys Cys Gly Thr Thr
13190 13195 13200
Cys Gly Cys Gly Cys Ala Thr Cys Thr Gly Cys Ala Gly Cys Cys
13205 13210 13215
Cys Ala Ala Ala Cys Thr Gly Gly Gly Gly Cys Gly Ala Cys Gly
13220 13225 13230
Gly Ala Thr Gly Thr Thr Thr Thr Gly Ala Ala Thr Gly Ala Ala
13235 13240 13245
Ala Thr Ala Ala Ala Ala Cys Thr Cys Ala Cys Cys Ala Ala Gly
13250 13255 13260
Gly Cys Cys Ala Thr Ala Gly Cys Gly Thr Gly Cys Gly Thr Thr
13265 13270 13275
Cys Thr Cys Thr Thr Cys Cys Thr Thr Gly Thr Thr Ala Gly Ala
13280 13285 13290
Gly Ala Thr Gly Ala Gly Gly Cys Gly Cys Gly Cys Gly Gly Thr
13295 13300 13305
Gly Gly Thr Gly Thr Cys Thr Thr Cys Cys Thr Cys Thr Cys Cys
13310 13315 13320
Thr Cys Cys Thr Cys Cys Cys Thr Cys Gly Thr Ala Cys Gly Ala
13325 13330 13335
Gly Ala Gly Cys Gly Thr Gly Ala Thr Gly Gly Cys Gly Cys Ala
13340 13345 13350
Gly Gly Cys Gly Ala Cys Cys Cys Thr Gly Gly Ala Gly Gly Thr
13355 13360 13365
Thr Cys Cys Gly Thr Thr Thr Gly Thr Gly Cys Cys Thr Cys Cys
13370 13375 13380
Gly Cys Gly Gly Thr Ala Thr Ala Thr Gly Gly Cys Thr Cys Cys
13385 13390 13395
Thr Ala Cys Gly Gly Ala Gly Gly Gly Cys Ala Gly Ala Ala Ala
13400 13405 13410
Cys Ala Gly Cys Ala Thr Thr Cys Gly Thr Thr Ala Cys Thr Cys
13415 13420 13425
Gly Gly Ala Gly Cys Thr Gly Gly Cys Thr Cys Cys Gly Cys Ala
13430 13435 13440
Gly Thr Ala Cys Gly Ala Cys Ala Cys Cys Ala Cys Thr Cys Gly
13445 13450 13455
Cys Gly Thr Gly Thr Ala Cys Thr Thr Gly Gly Thr Gly Gly Ala
13460 13465 13470
Cys Ala Ala Cys Ala Ala Gly Thr Cys Gly Gly Cys Gly Gly Ala
13475 13480 13485
Cys Ala Thr Cys Gly Cys Thr Thr Cys Cys Cys Thr Gly Ala Ala
13490 13495 13500
Cys Thr Ala Cys Cys Ala Ala Ala Ala Cys Gly Ala Cys Cys Ala
13505 13510 13515
Cys Ala Gly Cys Ala Ala Cys Thr Thr Cys Cys Thr Gly Ala Cys
13520 13525 13530
Cys Ala Cys Gly Gly Thr Gly Gly Thr Gly Cys Ala Gly Ala Ala
13535 13540 13545
Cys Ala Ala Cys Gly Ala Thr Thr Thr Cys Ala Cys Cys Cys Cys
13550 13555 13560
Cys Gly Cys Cys Gly Ala Gly Gly Cys Cys Ala Gly Cys Ala Cys
13565 13570 13575
Gly Cys Ala Gly Ala Cys Gly Ala Thr Ala Ala Ala Thr Thr Thr
13580 13585 13590
Thr Gly Ala Cys Gly Ala Gly Cys Gly Gly Thr Cys Gly Cys Gly
13595 13600 13605
Gly Thr Gly Gly Gly Gly Cys Gly Gly Thr Gly Ala Thr Cys Thr
13610 13615 13620
Gly Ala Ala Gly Ala Cys Cys Ala Thr Thr Cys Thr Gly Cys Ala
13625 13630 13635
Cys Ala Cys Thr Ala Ala Cys Ala Thr Gly Cys Cys Cys Ala Ala
13640 13645 13650
Thr Gly Thr Gly Ala Ala Cys Gly Ala Gly Thr Ala Cys Ala Thr
13655 13660 13665
Gly Thr Thr Cys Ala Cys Cys Ala Gly Cys Ala Ala Gly Thr Thr
13670 13675 13680
Thr Ala Ala Gly Gly Cys Gly Cys Gly Gly Gly Thr Gly Ala Thr
13685 13690 13695
Gly Gly Thr Gly Thr Cys Thr Ala Gly Gly Ala Ala Gly Cys Ala
13700 13705 13710
Thr Cys Cys Ala Gly Ala Gly Gly Gly Gly Gly Thr Ala Gly Thr
13715 13720 13725
Thr Gly Ala Ala Ala Cys Ala Gly Ala Thr Thr Thr Gly Ala Gly
13730 13735 13740
Thr Cys Ala Gly Gly Ala Thr Ala Ala Gly Cys Thr Thr Gly Ala
13745 13750 13755
Ala Thr Ala Thr Gly Ala Gly Thr Gly Gly Thr Thr Thr Gly Ala
13760 13765 13770
Gly Thr Thr Thr Ala Cys Cys Cys Thr Gly Cys Cys Cys Gly Ala
13775 13780 13785
Gly Gly Gly Ala Ala Ala Cys Thr Thr Thr Thr Cys Cys Gly Ala
13790 13795 13800
Gly Ala Cys Cys Ala Thr Gly Ala Cys Cys Ala Thr Ala Gly Ala
13805 13810 13815
Cys Cys Thr Gly Ala Thr Gly Ala Ala Cys Ala Ala Cys Gly Cys
13820 13825 13830
Cys Ala Thr Cys Thr Thr Gly Gly Ala Ala Ala Ala Cys Thr Ala
13835 13840 13845
Cys Thr Thr Gly Cys Ala Ala Gly Thr Gly Gly Gly Gly Cys Gly
13850 13855 13860
Gly Cys Ala Gly Ala Ala Thr Gly Gly Cys Gly Thr Gly Cys Thr
13865 13870 13875
Gly Gly Ala Gly Ala Gly Cys Gly Ala Thr Ala Thr Cys Gly Gly
13880 13885 13890
Ala Gly Thr Cys Ala Ala Gly Thr Thr Thr Gly Ala Cys Ala Gly
13895 13900 13905
Cys Ala Gly Ala Ala Ala Thr Thr Thr Cys Ala Ala Gly Cys Thr
13910 13915 13920
Gly Gly Gly Cys Thr Gly Gly Gly Ala Cys Cys Cys Gly Gly Thr
13925 13930 13935
Gly Ala Cys Cys Ala Ala Gly Cys Thr Gly Gly Thr Gly Ala Thr
13940 13945 13950
Gly Cys Cys Ala Gly Gly Gly Gly Thr Cys Thr Ala Cys Ala Cys
13955 13960 13965
Cys Thr Ala Cys Gly Ala Gly Gly Cys Cys Thr Thr Cys Cys Ala
13970 13975 13980
Cys Cys Cys Gly Gly Ala Cys Gly Thr Gly Gly Thr Gly Cys Thr
13985 13990 13995
Gly Cys Thr Gly Cys Cys Gly Gly Gly Cys Thr Gly Cys Gly Gly
14000 14005 14010
Gly Gly Thr Gly Gly Ala Cys Thr Thr Cys Ala Cys Cys Gly Ala
14015 14020 14025
Gly Ala Gly Cys Cys Gly Cys Cys Thr Gly Ala Gly Cys Ala Ala
14030 14035 14040
Cys Cys Thr Cys Cys Thr Gly Gly Gly Cys Ala Thr Thr Cys Gly
14045 14050 14055
Cys Ala Ala Gly Ala Ala Gly Cys Ala Ala Cys Cys Thr Thr Thr
14060 14065 14070
Cys Cys Ala Ala Gly Ala Gly Gly Gly Cys Thr Thr Cys Ala Gly
14075 14080 14085
Ala Ala Thr Cys Ala Thr Gly Thr Ala Thr Gly Ala Gly Gly Ala
14090 14095 14100
Thr Cys Thr Ala Gly Ala Ala Gly Gly Thr Gly Gly Cys Ala Ala
14105 14110 14115
Cys Ala Thr Cys Cys Cys Cys Gly Cys Cys Cys Thr Cys Cys Thr
14120 14125 14130
Thr Gly Ala Thr Gly Thr Gly Cys Cys Cys Ala Ala Gly Thr Ala
14135 14140 14145
Cys Thr Thr Gly Gly Ala Ala Ala Gly Cys Ala Ala Gly Ala Ala
14150 14155 14160
Gly Ala Ala Ala Gly Thr Thr Gly Ala Ala Gly Ala Cys Gly Ala
14165 14170 14175
Ala Ala Cys Thr Ala Ala Ala Ala Ala Thr Gly Cys Ala Gly Cys
14180 14185 14190
Thr Gly Cys Gly Gly Cys Cys Ala Cys Ala Gly Cys Cys Gly Ala
14195 14200 14205
Thr Ala Cys Ala Ala Cys Cys Ala Cys Thr Ala Gly Gly Gly Gly
14210 14215 14220
Thr Gly Ala Thr Ala Cys Ala Thr Thr Thr Gly Cys Ala Ala Cys
14225 14230 14235
Thr Cys Cys Ala Gly Cys Gly Cys Ala Ala Gly Ala Gly Ala Cys
14240 14245 14250
Ala Gly Cys Ala Gly Cys Thr Gly Ala Thr Ala Ala Gly Ala Ala
14255 14260 14265
Gly Gly Thr Ala Gly Ala Ala Gly Thr Cys Thr Thr Gly Cys Cys
14270 14275 14280
Cys Ala Thr Thr Gly Ala Ala Ala Ala Gly Gly Ala Thr Gly Ala
14285 14290 14295
Gly Ala Gly Thr Gly Gly Thr Ala Gly Ala Ala Gly Thr Thr Ala
14300 14305 14310
Cys Ala Ala Cys Cys Thr Gly Ala Thr Cys Cys Ala Gly Gly Gly
14315 14320 14325
Gly Ala Cys Cys Cys Ala Cys Gly Ala Cys Ala Cys Gly Cys Thr
14330 14335 14340
Gly Thr Ala Cys Cys Gly Cys Ala Gly Thr Thr Gly Gly Thr Ala
14345 14350 14355
Cys Cys Thr Gly Thr Cys Cys Thr Ala Thr Ala Cys Cys Thr Ala
14360 14365 14370
Cys Gly Gly Gly Gly Ala Cys Cys Cys Cys Gly Ala Gly Ala Ala
14375 14380 14385
Gly Gly Gly Gly Gly Thr Gly Cys Ala Gly Thr Cys Gly Thr Gly
14390 14395 14400
Gly Ala Cys Gly Cys Thr Gly Cys Thr Cys Ala Cys Cys Ala Cys
14405 14410 14415
Cys Cys Cys Gly Gly Ala Cys Gly Thr Thr Ala Cys Cys Thr Gly
14420 14425 14430
Cys Gly Gly Cys Gly Cys Gly Gly Ala Gly Cys Ala Ala Gly Thr
14435 14440 14445
Cys Thr Ala Cys Thr Gly Gly Thr Cys Ala Cys Thr Gly Cys Cys
14450 14455 14460
Gly Gly Ala Cys Cys Thr Cys Ala Thr Gly Cys Ala Ala Gly Ala
14465 14470 14475
Cys Cys Cys Cys Gly Thr Cys Ala Cys Cys Thr Thr Cys Cys Gly
14480 14485 14490
Cys Thr Cys Cys Ala Cys Cys Cys Ala Gly Cys Ala Ala Gly Thr
14495 14500 14505
Cys Ala Gly Cys Ala Ala Cys Thr Ala Cys Cys Cys Cys Gly Thr
14510 14515 14520
Gly Gly Thr Cys Gly Gly Cys Gly Cys Cys Gly Ala Gly Cys Thr
14525 14530 14535
Cys Ala Thr Gly Cys Cys Cys Thr Thr Cys Cys Gly Cys Gly Cys
14540 14545 14550
Cys Ala Ala Gly Ala Gly Cys Thr Thr Thr Thr Ala Cys Ala Ala
14555 14560 14565
Cys Gly Ala Cys Cys Thr Cys Gly Cys Cys Gly Thr Cys Thr Ala
14570 14575 14580
Cys Thr Cys Cys Cys Ala Gly Cys Thr Cys Ala Thr Cys Cys Gly
14585 14590 14595
Cys Ala Gly Cys Thr Ala Cys Ala Cys Cys Thr Cys Cys Cys Thr
14600 14605 14610
Cys Ala Cys Cys Cys Ala Cys Gly Thr Cys Thr Thr Cys Ala Ala
14615 14620 14625
Cys Cys Gly Cys Thr Thr Cys Cys Cys Cys Gly Ala Cys Ala Ala
14630 14635 14640
Cys Cys Ala Gly Ala Thr Cys Cys Thr Cys Thr Gly Cys Cys Gly
14645 14650 14655
Cys Cys Cys Gly Cys Cys Cys Gly Cys Gly Cys Cys Cys Ala Cys
14660 14665 14670
Cys Ala Thr Cys Ala Cys Cys Ala Cys Cys Gly Thr Cys Ala Gly
14675 14680 14685
Thr Gly Ala Ala Ala Ala Cys Gly Thr Gly Cys Cys Thr Gly Cys
14690 14695 14700
Thr Cys Thr Cys Ala Cys Ala Gly Ala Thr Cys Ala Cys Gly Gly
14705 14710 14715
Gly Ala Cys Gly Cys Thr Ala Cys Cys Gly Cys Thr Gly Cys Gly
14720 14725 14730
Cys Ala Gly Cys Ala Gly Thr Ala Thr Cys Cys Gly Cys Gly Gly
14735 14740 14745
Ala Gly Thr Cys Cys Ala Gly Cys Gly Ala Gly Thr Gly Ala Cys
14750 14755 14760
Cys Gly Thr Cys Ala Cys Thr Gly Ala Cys Gly Cys Cys Cys Gly
14765 14770 14775
Thr Cys Gly Cys Cys Gly Cys Ala Cys Cys Thr Gly Thr Cys Cys
14780 14785 14790
Cys Thr Ala Cys Gly Thr Cys Thr Ala Cys Ala Ala Gly Gly Cys
14795 14800 14805
Cys Cys Thr Gly Gly Gly Cys Ala Thr Ala Gly Thr Cys Gly Cys
14810 14815 14820
Gly Cys Cys Gly Cys Gly Cys Gly Thr Gly Cys Thr Thr Thr Cys
14825 14830 14835
Cys Ala Gly Thr Cys Gly Cys Ala Cys Cys Thr Thr Cys Thr Ala
14840 14845 14850
Ala Ala Ala Ala Ala Ala Thr Gly Thr Cys Thr Ala Thr Thr Cys
14855 14860 14865
Thr Cys Ala Thr Cys Thr Cys Gly Cys Cys Cys Ala Gly Cys Ala
14870 14875 14880
Ala Thr Ala Ala Cys Ala Cys Cys Gly Gly Cys Thr Gly Gly Gly
14885 14890 14895
Gly Thr Cys Thr Thr Ala Cys Thr Ala Gly Ala Cys Cys Cys Ala
14900 14905 14910
Gly Cys Ala Cys Cys Ala Thr Gly Thr Ala Cys Gly Gly Ala Gly
14915 14920 14925
Gly Ala Gly Cys Cys Ala Ala Gly Ala Ala Gly Cys Gly Cys Thr
14930 14935 14940
Cys Cys Cys Ala Gly Cys Ala Gly Cys Ala Cys Cys Cys Cys Gly
14945 14950 14955
Thr Cys Cys Gly Cys Gly Thr Cys Cys Gly Cys Gly Gly Cys Cys
14960 14965 14970
Ala Cys Thr Thr Cys Cys Gly Cys Gly Cys Thr Cys Cys Cys Thr
14975 14980 14985
Gly Gly Gly Gly Cys Gly Cys Ala Thr Ala Cys Ala Ala Gly Cys
14990 14995 15000
Gly Cys Gly Gly Gly Cys Gly Gly Ala Cys Thr Thr Cys Cys Ala
15005 15010 15015
Cys Cys Gly Cys Cys Gly Cys Cys Gly Thr Gly Cys Gly Cys Ala
15020 15025 15030
Cys Cys Ala Cys Cys Gly Thr Cys Gly Ala Cys Gly Ala Cys Gly
15035 15040 15045
Thr Cys Ala Thr Cys Gly Ala Cys Thr Cys Gly Gly Thr Gly Gly
15050 15055 15060
Thr Cys Gly Cys Cys Gly Ala Cys Gly Cys Gly Cys Gly Cys Ala
15065 15070 15075
Ala Cys Thr Ala Thr Ala Cys Cys Cys Cys Cys Gly Cys Cys Cys
15080 15085 15090
Cys Cys Thr Cys Cys Ala Cys Cys Gly Thr Gly Gly Ala Cys Gly
15095 15100 15105
Cys Gly Gly Thr Cys Ala Thr Cys Gly Ala Cys Ala Gly Cys Gly
15110 15115 15120
Thr Gly Gly Thr Gly Gly Cys Cys Gly Ala Cys Gly Cys Gly Cys
15125 15130 15135
Gly Cys Gly Ala Cys Thr Ala Thr Gly Cys Cys Ala Gly Ala Cys
15140 15145 15150
Gly Cys Ala Ala Gly Ala Gly Cys Cys Gly Gly Cys Gly Gly Cys
15155 15160 15165
Gly Ala Cys Gly Gly Ala Thr Cys Gly Cys Cys Ala Gly Gly Cys
15170 15175 15180
Gly Cys Cys Ala Cys Cys Gly Gly Ala Gly Cys Ala Cys Gly Cys
15185 15190 15195
Cys Cys Gly Cys Cys Ala Thr Gly Cys Gly Cys Gly Cys Cys Gly
15200 15205 15210
Cys Cys Cys Gly Gly Gly Cys Thr Cys Thr Gly Cys Thr Gly Cys
15215 15220 15225
Gly Cys Cys Gly Cys Gly Cys Cys Ala Gly Ala Cys Gly Cys Ala
15230 15235 15240
Cys Gly Gly Gly Cys Cys Gly Cys Cys Gly Gly Gly Cys Cys Ala
15245 15250 15255
Thr Gly Ala Thr Gly Cys Gly Ala Gly Cys Cys Gly Cys Gly Cys
15260 15265 15270
Gly Cys Cys Gly Cys Gly Cys Thr Gly Cys Cys Ala Cys Thr Gly
15275 15280 15285
Cys Ala Cys Cys Cys Ala Cys Cys Cys Cys Cys Gly Cys Ala Gly
15290 15295 15300
Gly Cys Ala Gly Gly Ala Cys Thr Cys Gly Cys Ala Gly Ala Cys
15305 15310 15315
Gly Ala Gly Cys Gly Gly Cys Cys Gly Cys Cys Gly Cys Cys Gly
15320 15325 15330
Cys Cys Gly Cys Thr Gly Cys Gly Gly Cys Cys Ala Thr Cys Thr
15335 15340 15345
Cys Thr Ala Gly Cys Ala Thr Gly Ala Cys Cys Ala Gly Ala Cys
15350 15355 15360
Cys Cys Ala Gly Gly Cys Gly Cys Gly Gly Ala Ala Ala Cys Gly
15365 15370 15375
Thr Gly Thr Ala Cys Thr Gly Gly Gly Thr Gly Cys Gly Cys Gly
15380 15385 15390
Ala Cys Thr Cys Cys Gly Thr Cys Ala Cys Gly Gly Gly Cys Gly
15395 15400 15405
Thr Gly Cys Gly Cys Gly Thr Gly Cys Cys Cys Gly Thr Gly Cys
15410 15415 15420
Gly Cys Ala Cys Cys Cys Gly Thr Cys Cys Thr Cys Cys Thr Cys
15425 15430 15435
Gly Thr Cys Cys Cys Thr Gly Ala Thr Cys Thr Ala Ala Thr Gly
15440 15445 15450
Cys Thr Thr Gly Thr Gly Thr Cys Cys Thr Cys Cys Cys Cys Cys
15455 15460 15465
Gly Cys Ala Ala Gly Cys Gly Ala Cys Gly Ala Thr Gly Thr Cys
15470 15475 15480
Ala Ala Ala Gly Cys Gly Cys Ala Ala Ala Ala Thr Cys Ala Ala
15485 15490 15495
Gly Gly Ala Gly Gly Ala Gly Ala Thr Gly Cys Thr Cys Cys Ala
15500 15505 15510
Gly Gly Thr Cys Gly Thr Cys Gly Cys Cys Cys Cys Gly Gly Ala
15515 15520 15525
Gly Ala Thr Thr Thr Ala Cys Gly Gly Ala Cys Cys Ala Cys Cys
15530 15535 15540
Cys Cys Ala Gly Gly Cys Gly Gly Ala Cys Cys Ala Gly Ala Ala
15545 15550 15555
Ala Cys Cys Cys Cys Gly Cys Ala Ala Ala Ala Thr Cys Ala Ala
15560 15565 15570
Gly Cys Gly Gly Gly Thr Thr Ala Ala Ala Ala Ala Ala Ala Ala
15575 15580 15585
Gly Gly Ala Thr Gly Ala Gly Gly Thr Gly Gly Ala Cys Gly Ala
15590 15595 15600
Gly Gly Gly Gly Gly Cys Ala Gly Thr Ala Gly Ala Gly Thr Thr
15605 15610 15615
Thr Gly Thr Gly Cys Gly Cys Gly Ala Gly Thr Thr Cys Gly Cys
15620 15625 15630
Thr Cys Cys Gly Cys Gly Gly Cys Gly Gly Cys Gly Cys Gly Thr
15635 15640 15645
Ala Ala Ala Thr Thr Gly Gly Ala Ala Gly Gly Gly Gly Cys Gly
15650 15655 15660
Cys Ala Gly Gly Gly Thr Gly Cys Ala Gly Cys Gly Cys Gly Thr
15665 15670 15675
Gly Thr Thr Gly Cys Gly Gly Cys Cys Cys Gly Gly Cys Ala Cys
15680 15685 15690
Gly Gly Cys Gly Gly Thr Gly Gly Thr Gly Thr Thr Cys Ala Cys
15695 15700 15705
Gly Cys Cys Cys Gly Gly Cys Gly Ala Gly Cys Gly Gly Thr Cys
15710 15715 15720
Cys Thr Cys Gly Gly Thr Cys Ala Gly Gly Ala Gly Cys Ala Ala
15725 15730 15735
Gly Cys Gly Thr Ala Gly Cys Thr Ala Thr Gly Ala Cys Gly Ala
15740 15745 15750
Gly Gly Thr Gly Thr Ala Cys Gly Gly Cys Gly Ala Cys Gly Ala
15755 15760 15765
Cys Gly Ala Cys Ala Thr Cys Cys Thr Gly Gly Ala Cys Cys Ala
15770 15775 15780
Gly Gly Cys Gly Gly Cys Gly Gly Ala Gly Cys Gly Gly Gly Cys
15785 15790 15795
Gly Gly Gly Cys Gly Ala Gly Thr Thr Cys Gly Cys Cys Thr Ala
15800 15805 15810
Cys Gly Gly Gly Ala Ala Gly Cys Gly Gly Thr Cys Gly Cys Gly
15815 15820 15825
Cys Gly Ala Ala Gly Ala Gly Gly Ala Gly Cys Thr Gly Ala Thr
15830 15835 15840
Cys Thr Cys Gly Cys Thr Gly Cys Cys Gly Cys Thr Gly Gly Ala
15845 15850 15855
Cys Gly Ala Ala Ala Gly Cys Ala Ala Cys Cys Cys Cys Ala Cys
15860 15865 15870
Gly Cys Cys Gly Ala Gly Cys Cys Thr Gly Ala Ala Gly Cys Cys
15875 15880 15885
Cys Gly Thr Gly Ala Cys Cys Cys Thr Gly Cys Ala Gly Cys Ala
15890 15895 15900
Gly Gly Thr Gly Cys Thr Gly Cys Cys Cys Cys Ala Gly Gly Cys
15905 15910 15915
Gly Gly Thr Gly Cys Thr Gly Cys Thr Gly Cys Cys Gly Ala Gly
15920 15925 15930
Cys Cys Gly Cys Gly Gly Gly Gly Thr Cys Ala Ala Gly Cys Gly
15935 15940 15945
Cys Gly Ala Gly Gly Gly Cys Gly Ala Gly Ala Gly Cys Ala Thr
15950 15955 15960
Gly Thr Ala Cys Cys Cys Gly Ala Cys Cys Ala Thr Gly Cys Ala
15965 15970 15975
Gly Ala Thr Cys Ala Thr Gly Gly Thr Gly Cys Cys Cys Ala Ala
15980 15985 15990
Gly Cys Gly Cys Cys Gly Gly Cys Gly Cys Gly Thr Gly Gly Ala
15995 16000 16005
Gly Gly Ala Cys Gly Thr Gly Cys Thr Gly Gly Ala Cys Ala Cys
16010 16015 16020
Cys Gly Thr Gly Ala Ala Ala Ala Thr Gly Gly Ala Thr Gly Thr
16025 16030 16035
Gly Gly Ala Gly Cys Cys Cys Gly Ala Gly Gly Thr Cys Ala Ala
16040 16045 16050
Gly Gly Thr Gly Cys Gly Cys Cys Cys Cys Ala Thr Cys Ala Ala
16055 16060 16065
Gly Cys Ala Gly Gly Thr Gly Gly Cys Gly Cys Cys Gly Gly Gly
16070 16075 16080
Cys Cys Thr Gly Gly Gly Cys Gly Thr Gly Cys Ala Ala Ala Cys
16085 16090 16095
Cys Gly Thr Gly Gly Ala Cys Ala Thr Thr Cys Ala Gly Ala Thr
16100 16105 16110
Cys Cys Cys Cys Ala Cys Cys Gly Ala Cys Ala Thr Gly Gly Ala
16115 16120 16125
Thr Gly Thr Cys Gly Ala Cys Ala Ala Ala Ala Ala Ala Cys Cys
16130 16135 16140
Cys Thr Cys Gly Ala Cys Cys Ala Gly Cys Ala Thr Cys Gly Ala
16145 16150 16155
Gly Gly Thr Gly Cys Ala Ala Ala Cys Cys Gly Ala Cys Cys Cys
16160 16165 16170
Cys Thr Gly Gly Cys Thr Cys Cys Cys Ala Gly Cys Cys Thr Cys
16175 16180 16185
Cys Ala Cys Cys Gly Cys Thr Ala Cys Cys Gly Thr Cys Thr Cys
16190 16195 16200
Cys Ala Cys Thr Thr Cys Thr Ala Cys Cys Gly Cys Cys Gly Cys
16205 16210 16215
Cys Ala Cys Gly Gly Cys Thr Ala Cys Cys Gly Ala Gly Cys Cys
16220 16225 16230
Thr Cys Cys Cys Ala Gly Gly Ala Gly Gly Cys Gly Ala Ala Gly
16235 16240 16245
Ala Thr Gly Gly Gly Gly Cys Gly Cys Cys Gly Cys Cys Ala Gly
16250 16255 16260
Cys Cys Gly Gly Cys Thr Gly Ala Thr Gly Cys Cys Cys Ala Ala
16265 16270 16275
Cys Thr Ala Cys Gly Thr Gly Thr Thr Gly Cys Ala Thr Cys Cys
16280 16285 16290
Thr Thr Cys Cys Ala Thr Cys Ala Thr Cys Cys Cys Gly Ala Cys
16295 16300 16305
Gly Cys Cys Gly Gly Gly Cys Thr Ala Cys Cys Gly Cys Gly Gly
16310 16315 16320
Cys Ala Cys Cys Cys Gly Gly Thr Ala Cys Thr Ala Cys Gly Cys
16325 16330 16335
Cys Ala Gly Cys Cys Gly Cys Cys Gly Gly Cys Gly Cys Cys Cys
16340 16345 16350
Ala Gly Cys Cys Ala Gly Cys Ala Ala Ala Cys Gly Cys Cys Gly
16355 16360 16365
Cys Cys Gly Cys Cys Gly Cys Ala Cys Cys Gly Cys Cys Ala Cys
16370 16375 16380
Cys Cys Gly Cys Cys Gly Cys Cys Gly Thr Cys Thr Gly Gly Cys
16385 16390 16395
Cys Cys Cys Cys Gly Cys Cys Cys Gly Cys Gly Thr Gly Cys Gly
16400 16405 16410
Cys Cys Gly Cys Gly Thr Gly Ala Cys Cys Ala Cys Gly Cys Gly
16415 16420 16425
Cys Cys Gly Gly Gly Gly Cys Cys Gly Cys Thr Cys Gly Cys Thr
16430 16435 16440
Cys Gly Thr Thr Cys Thr Gly Cys Cys Cys Ala Cys Cys Gly Thr
16445 16450 16455
Gly Cys Gly Cys Thr Ala Cys Cys Ala Cys Cys Cys Cys Ala Gly
16460 16465 16470
Cys Ala Thr Cys Cys Thr Thr Thr Ala Ala Thr Cys Cys Gly Thr
16475 16480 16485
Gly Thr Gly Cys Thr Gly Thr Gly Ala Thr Ala Cys Thr Gly Thr
16490 16495 16500
Thr Gly Cys Ala Gly Ala Gly Ala Gly Ala Thr Gly Gly Cys Thr
16505 16510 16515
Cys Thr Cys Ala Cys Thr Thr Gly Cys Cys Gly Cys Cys Thr Gly
16520 16525 16530
Cys Gly Cys Ala Thr Cys Cys Cys Cys Gly Thr Cys Cys Cys Gly
16535 16540 16545
Ala Ala Thr Thr Ala Cys Cys Gly Ala Gly Gly Ala Ala Gly Ala
16550 16555 16560
Thr Cys Cys Cys Gly Cys Cys Gly Cys Ala Gly Gly Ala Gly Ala
16565 16570 16575
Gly Gly Cys Ala Thr Gly Gly Cys Ala Gly Gly Cys Ala Gly Cys
16580 16585 16590
Gly Gly Cys Cys Thr Gly Ala Ala Cys Cys Gly Cys Cys Gly Cys
16595 16600 16605
Cys Gly Gly Cys Gly Gly Cys Gly Gly Gly Cys Cys Ala Thr Gly
16610 16615 16620
Cys Gly Cys Ala Gly Gly Cys Gly Cys Cys Thr Gly Ala Gly Thr
16625 16630 16635
Gly Gly Cys Gly Gly Cys Thr Thr Thr Cys Thr Gly Cys Cys Cys
16640 16645 16650
Gly Cys Gly Cys Thr Cys Ala Thr Cys Cys Cys Cys Ala Thr Ala
16655 16660 16665
Ala Thr Cys Gly Cys Cys Gly Cys Gly Gly Cys Cys Ala Thr Thr
16670 16675 16680
Gly Gly Cys Ala Cys Gly Ala Thr Cys Cys Cys Gly Gly Gly Cys
16685 16690 16695
Ala Thr Ala Gly Cys Thr Thr Cys Cys Gly Thr Thr Gly Cys Gly
16700 16705 16710
Cys Thr Gly Cys Ala Gly Gly Cys Gly Thr Cys Gly Cys Ala Gly
16715 16720 16725
Cys Gly Cys Cys Gly Thr Thr Gly Ala Thr Gly Thr Gly Cys Gly
16730 16735 16740
Ala Ala Thr Ala Ala Ala Gly Cys Cys Thr Cys Thr Thr Thr Ala
16745 16750 16755
Gly Ala Cys Thr Cys Thr Gly Ala Cys Ala Cys Ala Cys Cys Thr
16760 16765 16770
Gly Gly Thr Cys Cys Thr Gly Thr Ala Thr Ala Thr Thr Thr Thr
16775 16780 16785
Thr Ala Gly Ala Ala Thr Gly Gly Ala Ala Gly Ala Cys Ala Thr
16790 16795 16800
Cys Ala Ala Thr Thr Thr Thr Gly Cys Gly Thr Cys Cys Cys Thr
16805 16810 16815
Gly Gly Cys Thr Cys Cys Gly Cys Gly Gly Cys Ala Cys Gly Gly
16820 16825 16830
Cys Ala Cys Gly Cys Gly Gly Cys Cys Gly Thr Thr Cys Ala Thr
16835 16840 16845
Gly Gly Gly Cys Ala Cys Cys Thr Gly Gly Ala Ala Cys Gly Ala
16850 16855 16860
Gly Ala Thr Cys Gly Gly Cys Ala Cys Cys Ala Gly Cys Cys Ala
16865 16870 16875
Gly Cys Thr Gly Ala Ala Cys Gly Gly Gly Gly Gly Cys Gly Cys
16880 16885 16890
Cys Thr Thr Cys Ala Ala Thr Thr Gly Gly Ala Gly Cys Ala Gly
16895 16900 16905
Thr Gly Thr Cys Thr Gly Gly Ala Gly Cys Gly Gly Gly Cys Thr
16910 16915 16920
Thr Ala Ala Ala Ala Ala Thr Thr Thr Cys Gly Gly Cys Thr Cys
16925 16930 16935
Gly Ala Cys Gly Cys Thr Cys Cys Gly Gly Ala Cys Cys Thr Ala
16940 16945 16950
Thr Gly Gly Gly Ala Ala Cys Ala Ala Gly Gly Cys Cys Thr Gly
16955 16960 16965
Gly Ala Ala Thr Ala Gly Thr Ala Gly Cys Ala Cys Gly Gly Gly
16970 16975 16980
Gly Cys Ala Gly Thr Thr Gly Thr Thr Gly Ala Gly Gly Gly Ala
16985 16990 16995
Ala Ala Ala Gly Cys Thr Cys Ala Ala Ala Gly Ala Cys Cys Ala
17000 17005 17010
Gly Ala Ala Cys Thr Thr Cys Cys Ala Gly Cys Ala Gly Ala Ala
17015 17020 17025
Gly Gly Thr Gly Gly Thr Gly Gly Ala Cys Gly Gly Gly Cys Thr
17030 17035 17040
Gly Gly Cys Cys Thr Cys Gly Gly Gly Cys Ala Thr Thr Ala Ala
17045 17050 17055
Cys Gly Gly Gly Gly Thr Gly Gly Thr Gly Gly Ala Cys Ala Thr
17060 17065 17070
Cys Gly Cys Gly Ala Ala Cys Cys Ala Gly Gly Cys Cys Gly Thr
17075 17080 17085
Gly Cys Ala Gly Cys Gly Cys Gly Ala Gly Ala Thr Ala Ala Ala
17090 17095 17100
Cys Ala Gly Cys Cys Gly Cys Cys Thr Gly Gly Ala Cys Cys Cys
17105 17110 17115
Gly Cys Gly Ala Cys Cys Gly Cys Cys Cys Ala Cys Gly Gly Thr
17120 17125 17130
Gly Gly Thr Gly Gly Ala Gly Ala Thr Gly Gly Ala Ala Gly Ala
17135 17140 17145
Thr Gly Cys Ala Ala Cys Thr Cys Thr Thr Cys Cys Gly Cys Cys
17150 17155 17160
Gly Cys Cys Cys Ala Ala Gly Gly Gly Cys Gly Ala Gly Ala Ala
17165 17170 17175
Gly Cys Gly Gly Cys Cys Gly Cys Gly Gly Cys Cys Cys Gly Ala
17180 17185 17190
Cys Gly Cys Gly Gly Ala Gly Gly Ala Gly Ala Cys Gly Ala Thr
17195 17200 17205
Cys Cys Thr Gly Cys Ala Gly Gly Thr Gly Gly Ala Cys Gly Ala
17210 17215 17220
Gly Cys Cys Gly Cys Cys Cys Thr Cys Gly Thr Ala Cys Gly Ala
17225 17230 17235
Gly Gly Ala Gly Gly Cys Cys Gly Thr Cys Ala Ala Gly Gly Cys
17240 17245 17250
Cys Gly Gly Cys Ala Thr Gly Cys Cys Cys Ala Cys Cys Ala Cys
17255 17260 17265
Gly Cys Gly Cys Ala Thr Cys Ala Thr Cys Gly Cys Gly Cys Cys
17270 17275 17280
Gly Cys Thr Gly Gly Cys Cys Ala Cys Gly Gly Gly Thr Gly Thr
17285 17290 17295
Ala Ala Thr Gly Ala Ala Ala Cys Cys Cys Gly Cys Cys Ala Cys
17300 17305 17310
Cys Cys Thr Thr Gly Ala Cys Cys Thr Gly Cys Cys Thr Cys Cys
17315 17320 17325
Ala Cys Cys Ala Cys Cys Cys Gly Cys Gly Cys Cys Cys Gly Cys
17330 17335 17340
Thr Cys Cys Ala Cys Cys Gly Ala Ala Gly Gly Cys Ala Ala Cys
17345 17350 17355
Thr Cys Cys Gly Gly Thr Thr Gly Thr Gly Cys Ala Gly Gly Cys
17360 17365 17370
Cys Cys Cys Cys Cys Cys Gly Gly Thr Gly Gly Cys Gly Ala Cys
17375 17380 17385
Cys Gly Cys Cys Gly Thr Gly Cys Gly Cys Cys Gly Cys Gly Thr
17390 17395 17400
Cys Cys Cys Cys Gly Cys Cys Cys Gly Cys Cys Gly Cys Cys Ala
17405 17410 17415
Gly Gly Cys Cys Cys Ala Gly Ala Ala Cys Thr Gly Gly Cys Ala
17420 17425 17430
Gly Ala Gly Cys Ala Cys Gly Cys Thr Gly Cys Ala Cys Ala Gly
17435 17440 17445
Thr Ala Thr Cys Gly Thr Gly Gly Gly Cys Cys Thr Gly Gly Gly
17450 17455 17460
Ala Gly Thr Gly Ala Ala Ala Ala Gly Thr Cys Thr Gly Ala Ala
17465 17470 17475
Gly Cys Gly Cys Cys Gly Cys Cys Gly Ala Thr Gly Cys Thr Ala
17480 17485 17490
Thr Thr Gly Ala Gly Ala Gly Ala Gly Ala Gly Gly Ala Ala Ala
17495 17500 17505
Gly Ala Gly Gly Ala Cys Ala Cys Thr Ala Ala Ala Gly Gly Gly
17510 17515 17520
Ala Gly Ala Gly Cys Thr Thr Ala Ala Cys Thr Thr Gly Thr Ala
17525 17530 17535
Thr Gly Thr Gly Cys Cys Thr Thr Ala Cys Cys Gly Cys Cys Ala
17540 17545 17550
Gly Ala Gly Ala Ala Cys Gly Cys Gly Cys Gly Ala Ala Gly Ala
17555 17560 17565
Thr Gly Gly Cys Cys Ala Cys Cys Cys Cys Cys Thr Cys Gly Ala
17570 17575 17580
Thr Gly Ala Thr Gly Cys Cys Gly Cys Ala Gly Thr Gly Gly Gly
17585 17590 17595
Cys Gly Thr Ala Cys Ala Thr Gly Cys Ala Cys Ala Thr Cys Gly
17600 17605 17610
Cys Cys Gly Gly Gly Cys Ala Gly Gly Ala Cys Gly Cys Cys Thr
17615 17620 17625
Cys Gly Gly Ala Gly Thr Ala Cys Cys Thr Gly Ala Gly Cys Cys
17630 17635 17640
Cys Gly Gly Gly Thr Cys Thr Gly Gly Thr Gly Cys Ala Gly Thr
17645 17650 17655
Thr Thr Gly Cys Cys Cys Gly Cys Gly Cys Cys Ala Cys Cys Gly
17660 17665 17670
Ala Cys Ala Cys Gly Thr Ala Cys Thr Thr Cys Ala Gly Cys Cys
17675 17680 17685
Thr Gly Gly Gly Cys Ala Ala Cys Ala Ala Gly Thr Thr Thr Ala
17690 17695 17700
Gly Gly Ala Ala Cys Cys Cys Cys Ala Cys Gly Gly Thr Gly Gly
17705 17710 17715
Cys Cys Cys Cys Gly Ala Cys Cys Cys Ala Cys Gly Ala Thr Gly
17720 17725 17730
Thr Gly Ala Cys Cys Ala Cys Gly Gly Ala Cys Cys Gly Gly Thr
17735 17740 17745
Cys Cys Cys Ala Gly Cys Gly Thr Cys Thr Gly Ala Cys Gly Cys
17750 17755 17760
Thr Gly Cys Gly Cys Thr Thr Cys Gly Thr Gly Cys Cys Cys Gly
17765 17770 17775
Thr Gly Gly Ala Thr Cys Gly Cys Gly Ala Gly Gly Ala Cys Ala
17780 17785 17790
Cys Cys Ala Cys Gly Thr Ala Cys Thr Cys Gly Thr Ala Cys Ala
17795 17800 17805
Ala Gly Gly Cys Gly Cys Gly Cys Thr Thr Cys Ala Cys Thr Cys
17810 17815 17820
Thr Gly Gly Cys Cys Gly Thr Gly Gly Gly Cys Gly Ala Cys Ala
17825 17830 17835
Ala Cys Cys Gly Gly Gly Thr Gly Cys Thr Ala Gly Ala Cys Ala
17840 17845 17850
Thr Gly Gly Cys Cys Ala Gly Cys Ala Cys Thr Thr Ala Cys Thr
17855 17860 17865
Thr Thr Gly Ala Cys Ala Thr Cys Cys Gly Cys Gly Gly Cys Gly
17870 17875 17880
Thr Cys Cys Thr Gly Gly Ala Cys Cys Gly Cys Gly Gly Thr Cys
17885 17890 17895
Cys Cys Ala Gly Cys Thr Thr Cys Ala Ala Ala Cys Cys Cys Thr
17900 17905 17910
Ala Cys Thr Cys Gly Gly Gly Cys Ala Cys Gly Gly Cys Cys Thr
17915 17920 17925
Ala Cys Ala Ala Cys Ala Gly Cys Cys Thr Gly Gly Cys Thr Cys
17930 17935 17940
Cys Cys Ala Ala Gly Gly Gly Thr Gly Cys Cys Cys Cys Cys Ala
17945 17950 17955
Ala Thr Cys Cys Cys Ala Gly Cys Cys Ala Gly Thr Gly Gly Gly
17960 17965 17970
Ala Gly Cys Ala Ala Ala Ala Thr Gly Ala Ala Ala Cys Cys Ala
17975 17980 17985
Ala Thr Gly Thr Thr Ala Ala Thr Ala Ala Ala Ala Cys Ala Cys
17990 17995 18000
Ala Cys Ala Cys Cys Thr Thr Thr Gly Gly Gly Ala Thr Gly Gly
18005 18010 18015
Cys Ala Gly Cys Cys Ala Thr Gly Ala Ala Ala Gly Gly Ala Gly
18020 18025 18030
Ala Ala Gly Cys Thr Ala Thr Thr Gly Ala Cys Ala Ala Ala Ala
18035 18040 18045
Ala Thr Gly Gly Thr Cys Thr Gly Cys Ala Ala Ala Thr Thr Gly
18050 18055 18060
Gly Ala Ala Cys Thr Gly Ala Cys Gly Cys Gly Gly Cys Gly Gly
18065 18070 18075
Ala Thr Cys Ala Gly Gly Ala Thr Ala Ala Ala Cys Cys Ala Ala
18080 18085 18090
Thr Thr Thr Ala Thr Gly Cys Ala Gly Ala Thr Ala Ala Ala Ala
18095 18100 18105
Cys Thr Thr Thr Cys Cys Ala Gly Cys Cys Ala Gly Ala Ala Cys
18110 18115 18120
Cys Thr Cys Ala Ala Gly Thr Ala Gly Gly Ala Gly Ala Gly Gly
18125 18130 18135
Ala Ala Gly Ala Cys Thr Gly Gly Ala Thr Thr Gly Ala Thr Ala
18140 18145 18150
Ala Ala Gly Cys Ala Gly Ala Thr Thr Thr Cys Thr Ala Thr Gly
18155 18160 18165
Gly Cys Gly Gly Ala Ala Gly Ala Gly Cys Thr Cys Thr Thr Ala
18170 18175 18180
Ala Ala Ala Ala Ala Gly Ala Cys Ala Cys Thr Ala Ala Ala Ala
18185 18190 18195
Thr Gly Ala Ala Ala Cys Cys Ala Thr Gly Cys Thr Ala Thr Gly
18200 18205 18210
Gly Ala Thr Cys Thr Thr Thr Thr Gly Cys Thr Ala Gly Ala Cys
18215 18220 18225
Cys Thr Ala Cys Thr Ala Ala Thr Gly Ala Gly Ala Ala Ala Gly
18230 18235 18240
Gly Ala Gly Gly Thr Cys Ala Gly Gly Cys Ala Ala Ala Gly Thr
18245 18250 18255
Thr Cys Ala Ala Ala Cys Cys Ala Gly Thr Thr Ala Ala Thr Gly
18260 18265 18270
Ala Ala Gly Gly Ala Gly Ala Ala Cys Ala Ala Cys Cys Thr Ala
18275 18280 18285
Ala Ala Gly Ala Thr Cys Thr Gly Gly Ala Thr Ala Thr Ala Gly
18290 18295 18300
Ala Thr Ala Thr Gly Ala Ala Cys Thr Thr Cys Thr Thr Thr Gly
18305 18310 18315
Ala Cys Cys Cys Ala Ala Cys Cys Ala Cys Thr Ala Thr Thr Ala
18320 18325 18330
Ala Cys Ala Cys Ala Cys Cys Ala Gly Ala Thr Gly Thr Ala Gly
18335 18340 18345
Thr Gly Cys Thr Gly Thr Ala Cys Ala Cys Thr Gly Ala Ala Ala
18350 18355 18360
Ala Thr Gly Thr Thr Ala Ala Thr Cys Thr Thr Gly Ala Ala Ala
18365 18370 18375
Cys Ala Cys Cys Ala Gly Ala Cys Ala Cys Thr Cys Ala Thr Gly
18380 18385 18390
Thr Gly Gly Thr Thr Thr Ala Cys Ala Ala Gly Gly Cys Ala Gly
18395 18400 18405
Gly Ala Ala Cys Thr Thr Cys Ala Gly Ala Thr Gly Ala Cys Ala
18410 18415 18420
Gly Thr Thr Cys Thr Gly Ala Gly Gly Thr Cys Ala Ala Thr Thr
18425 18430 18435
Thr Gly Gly Cys Thr Cys Ala Gly Cys Ala Gly Thr Cys Cys Ala
18440 18445 18450
Thr Gly Cys Cys Ala Ala Ala Cys Ala Gly Ala Cys Cys Cys Ala
18455 18460 18465
Ala Cys Thr Ala Cys Ala Thr Thr Gly Gly Cys Thr Thr Thr Ala
18470 18475 18480
Gly Gly Gly Ala Cys Ala Ala Cys Thr Thr Thr Gly Thr Ala Gly
18485 18490 18495
Gly Thr Cys Thr Cys Ala Thr Gly Thr Ala Thr Thr Ala Cys Ala
18500 18505 18510
Ala Cys Ala Gly Cys Ala Cys Cys Gly Gly Ala Ala Ala Thr Ala
18515 18520 18525
Thr Gly Gly Gly Thr Gly Thr Gly Cys Thr Gly Gly Cys Thr Gly
18530 18535 18540
Gly Thr Cys Ala Gly Gly Cys Thr Thr Cys Thr Cys Ala Gly Thr
18545 18550 18555
Thr Gly Ala Ala Cys Gly Cys Thr Gly Thr Gly Gly Thr Cys Gly
18560 18565 18570
Ala Cys Thr Thr Gly Cys Ala Ala Gly Ala Cys Ala Gly Ala Ala
18575 18580 18585
Ala Cys Ala Cys Cys Gly Ala Gly Thr Thr Ala Thr Cys Thr Thr
18590 18595 18600
Ala Cys Cys Ala Gly Cys Thr Ala Thr Thr Gly Cys Thr Ala Gly
18605 18610 18615
Ala Thr Thr Cys Thr Cys Thr Gly Gly Gly Thr Gly Ala Cys Ala
18620 18625 18630
Gly Ala Ala Cys Cys Ala Gly Ala Thr Ala Cys Thr Thr Thr Ala
18635 18640 18645
Gly Cys Ala Thr Gly Thr Gly Gly Ala Ala Cys Thr Cys Thr Gly
18650 18655 18660
Cys Gly Gly Thr Gly Gly Ala Cys Ala Gly Thr Thr Ala Cys Gly
18665 18670 18675
Ala Thr Cys Cys Ala Gly Ala Thr Gly Thr Cys Ala Gly Gly Ala
18680 18685 18690
Thr Cys Ala Thr Thr Gly Ala Ala Ala Ala Thr Cys Ala Cys Gly
18695 18700 18705
Gly Thr Gly Thr Gly Gly Ala Ala Gly Ala Thr Gly Ala Ala Cys
18710 18715 18720
Thr Thr Cys Cys Ala Ala Ala Cys Thr Ala Thr Thr Gly Cys Thr
18725 18730 18735
Thr Cys Cys Cys Ala Thr Thr Gly Gly Ala Thr Gly Gly Thr Gly
18740 18745 18750
Thr Gly Gly Gly Cys Ala Cys Thr Ala Ala Thr Ala Cys Thr Gly
18755 18760 18765
Cys Ala Thr Ala Cys Cys Ala Ala Gly Gly Cys Gly Thr Thr Ala
18770 18775 18780
Ala Ala Gly Thr Thr Ala Ala Gly Ala Cys Ala Ala Cys Thr Ala
18785 18790 18795
Ala Thr Gly Gly Ala Ala Ala Cys Gly Ala Cys Ala Cys Gly Thr
18800 18805 18810
Gly Gly Gly Ala Ala Ala Ala Ala Gly Ala Thr Gly Ala Ala Ala
18815 18820 18825
Cys Thr Gly Thr Thr Thr Ala Thr Gly Ala Gly Thr Thr Thr Ala
18830 18835 18840
Ala Thr Cys Ala Ala Ala Thr Thr Gly Gly Cys Ala Ala Gly Gly
18845 18850 18855
Gly Gly Gly Ala Thr Ala Thr Cys Thr Ala Thr Gly Cys Cys Ala
18860 18865 18870
Thr Gly Gly Ala Gly Ala Thr Cys Ala Ala Cys Cys Thr Gly Cys
18875 18880 18885
Ala Gly Gly Cys Cys Ala Ala Cys Cys Thr Gly Thr Gly Gly Ala
18890 18895 18900
Ala Gly Ala Gly Thr Thr Thr Thr Cys Thr Gly Thr Ala Cys Thr
18905 18910 18915
Cys Gly Ala Ala Cys Gly Thr Gly Gly Cys Cys Cys Thr Gly Thr
18920 18925 18930
Ala Cys Cys Thr Gly Cys Cys Cys Gly Ala Cys Thr Cys Cys Thr
18935 18940 18945
Ala Cys Ala Ala Gly Thr Ala Cys Ala Cys Gly Cys Cys Gly Gly
18950 18955 18960
Cys Cys Ala Ala Cys Gly Thr Cys Ala Ala Gly Cys Thr Gly Cys
18965 18970 18975
Cys Cys Gly Cys Cys Ala Ala Cys Ala Cys Cys Ala Ala Cys Ala
18980 18985 18990
Cys Cys Thr Ala Cys Gly Ala Gly Thr Ala Cys Ala Thr Gly Ala
18995 19000 19005
Ala Cys Gly Gly Cys Cys Gly Cys Gly Thr Gly Gly Thr Ala Gly
19010 19015 19020
Cys Cys Cys Cys Cys Thr Cys Gly Cys Thr Gly Gly Thr Gly Gly
19025 19030 19035
Ala Cys Gly Cys Cys Thr Ala Cys Ala Thr Cys Ala Ala Cys Ala
19040 19045 19050
Thr Cys Gly Gly Cys Gly Cys Cys Cys Gly Cys Thr Gly Gly Thr
19055 19060 19065
Cys Gly Thr Thr Gly Gly Ala Thr Cys Cys Cys Ala Thr Gly Gly
19070 19075 19080
Ala Cys Ala Ala Cys Gly Thr Cys Ala Ala Cys Cys Cys Cys Thr
19085 19090 19095
Thr Cys Ala Ala Cys Cys Ala Cys Cys Ala Cys Cys Gly Cys Ala
19100 19105 19110
Ala Thr Gly Cys Gly Gly Gly Cys Cys Thr Gly Cys Gly Cys Thr
19115 19120 19125
Ala Cys Cys Gly Cys Thr Cys Cys Ala Thr Gly Cys Thr Gly Cys
19130 19135 19140
Thr Gly Gly Gly Cys Ala Ala Cys Gly Gly Cys Cys Gly Cys Thr
19145 19150 19155
Ala Cys Gly Thr Gly Cys Cys Cys Thr Thr Cys Cys Ala Cys Ala
19160 19165 19170
Thr Cys Cys Ala Ala Gly Thr Gly Cys Cys Cys Cys Ala Ala Ala
19175 19180 19185
Ala Gly Thr Thr Cys Thr Thr Thr Gly Cys Cys Ala Thr Cys Ala
19190 19195 19200
Ala Gly Ala Ala Cys Cys Thr Gly Cys Thr Cys Cys Thr Gly Cys
19205 19210 19215
Thr Cys Cys Cys Gly Gly Gly Cys Thr Cys Cys Thr Ala Cys Ala
19220 19225 19230
Cys Cys Thr Ala Cys Gly Ala Gly Thr Gly Gly Ala Ala Cys Thr
19235 19240 19245
Thr Cys Cys Gly Cys Ala Ala Gly Gly Ala Cys Gly Thr Cys Ala
19250 19255 19260
Ala Cys Ala Thr Gly Ala Thr Cys Cys Thr Gly Cys Ala Gly Ala
19265 19270 19275
Gly Thr Thr Cys Cys Cys Thr Cys Gly Gly Cys Ala Ala Cys Gly
19280 19285 19290
Ala Cys Cys Thr Gly Cys Gly Cys Gly Thr Cys Gly Ala Cys Gly
19295 19300 19305
Gly Cys Gly Cys Cys Thr Cys Cys Gly Thr Cys Cys Gly Cys Thr
19310 19315 19320
Thr Cys Gly Ala Cys Ala Gly Cys Gly Thr Cys Ala Ala Cys Cys
19325 19330 19335
Thr Ala Thr Ala Cys Gly Cys Cys Ala Cys Thr Thr Thr Cys Thr
19340 19345 19350
Thr Cys Cys Cys Cys Ala Thr Gly Gly Cys Gly Cys Ala Cys Ala
19355 19360 19365
Ala Cys Ala Cys Cys Gly Cys Thr Thr Cys Ala Ala Cys Cys Thr
19370 19375 19380
Thr Gly Gly Ala Ala Gly Cys Cys Ala Thr Gly Cys Thr Gly Cys
19385 19390 19395
Gly Cys Ala Ala Cys Gly Ala Cys Ala Cys Cys Ala Ala Cys Gly
19400 19405 19410
Ala Cys Cys Ala Gly Thr Cys Cys Thr Thr Cys Ala Ala Cys Gly
19415 19420 19425
Ala Cys Thr Ala Cys Cys Thr Cys Thr Cys Gly Gly Cys Cys Gly
19430 19435 19440
Cys Cys Ala Ala Cys Ala Thr Gly Cys Thr Cys Thr Ala Cys Cys
19445 19450 19455
Cys Cys Ala Thr Cys Cys Cys Gly Gly Cys Cys Ala Ala Gly Gly
19460 19465 19470
Cys Cys Ala Cys Cys Ala Ala Cys Gly Thr Gly Cys Cys Cys Ala
19475 19480 19485
Thr Cys Thr Cys Cys Ala Thr Cys Cys Cys Ala Thr Cys Gly Cys
19490 19495 19500
Gly Cys Ala Ala Cys Thr Gly Gly Gly Cys Cys Gly Cys Cys Thr
19505 19510 19515
Thr Cys Cys Gly Cys Gly Gly Cys Thr Gly Gly Ala Gly Thr Thr
19520 19525 19530
Thr Cys Ala Cys Cys Cys Gly Gly Cys Thr Cys Ala Ala Gly Ala
19535 19540 19545
Cys Cys Ala Ala Gly Gly Ala Ala Ala Cys Thr Cys Cys Thr Thr
19550 19555 19560
Cys Cys Cys Thr Cys Gly Gly Cys Thr Cys Gly Gly Gly Thr Thr
19565 19570 19575
Thr Cys Gly Ala Cys Cys Cys Cys Thr Ala Cys Thr Thr Thr Gly
19580 19585 19590
Thr Cys Thr Ala Cys Thr Cys Gly Gly Gly Cys Thr Cys Cys Ala
19595 19600 19605
Thr Cys Cys Cys Cys Thr Ala Cys Cys Thr Cys Gly Ala Cys Gly
19610 19615 19620
Gly Gly Ala Cys Cys Thr Thr Cys Thr Ala Cys Cys Thr Cys Ala
19625 19630 19635
Ala Cys Cys Ala Cys Ala Cys Cys Thr Thr Cys Ala Ala Gly Ala
19640 19645 19650
Ala Gly Gly Thr Cys Thr Cys Cys Ala Thr Cys Ala Thr Gly Thr
19655 19660 19665
Thr Cys Gly Ala Cys Thr Cys Cys Thr Cys Gly Gly Thr Cys Ala
19670 19675 19680
Gly Cys Thr Gly Gly Cys Cys Cys Gly Gly Cys Ala Ala Cys Gly
19685 19690 19695
Ala Cys Cys Gly Gly Cys Thr Gly Cys Thr Cys Ala Cys Gly Cys
19700 19705 19710
Cys Gly Ala Ala Cys Gly Ala Gly Thr Thr Cys Gly Ala Gly Ala
19715 19720 19725
Thr Cys Ala Ala Gly Cys Gly Cys Ala Gly Cys Gly Thr Cys Gly
19730 19735 19740
Ala Cys Gly Gly Gly Gly Ala Gly Gly Gly Cys Thr Ala Cys Ala
19745 19750 19755
Ala Cys Gly Thr Gly Gly Cys Cys Cys Ala Ala Thr Gly Cys Ala
19760 19765 19770
Ala Cys Ala Thr Gly Ala Cys Cys Ala Ala Gly Gly Ala Cys Thr
19775 19780 19785
Gly Gly Thr Thr Cys Cys Thr Cys Gly Thr Cys Cys Ala Gly Ala
19790 19795 19800
Thr Gly Cys Thr Cys Thr Cys Cys Cys Ala Cys Thr Ala Cys Ala
19805 19810 19815
Ala Cys Ala Thr Cys Gly Gly Cys Thr Ala Cys Cys Ala Gly Gly
19820 19825 19830
Gly Cys Thr Thr Cys Cys Ala Cys Gly Thr Gly Cys Cys Cys Gly
19835 19840 19845
Ala Gly Gly Gly Cys Thr Ala Cys Ala Ala Gly Gly Ala Cys Cys
19850 19855 19860
Gly Cys Ala Thr Gly Thr Ala Cys Thr Cys Cys Thr Thr Cys Thr
19865 19870 19875
Thr Cys Cys Gly Cys Ala Ala Cys Thr Thr Cys Cys Ala Gly Cys
19880 19885 19890
Cys Cys Ala Thr Gly Ala Gly Cys Ala Gly Gly Cys Ala Gly Gly
19895 19900 19905
Thr Gly Gly Thr Cys Gly Ala Thr Gly Ala Gly Ala Thr Cys Ala
19910 19915 19920
Ala Cys Thr Ala Cys Ala Ala Gly Gly Ala Cys Thr Ala Cys Ala
19925 19930 19935
Ala Gly Gly Cys Cys Gly Thr Cys Ala Cys Cys Cys Thr Gly Cys
19940 19945 19950
Cys Cys Thr Thr Cys Cys Ala Gly Cys Ala Cys Ala Ala Thr Ala
19955 19960 19965
Ala Cys Thr Cys Gly Gly Gly Cys Thr Thr Cys Ala Cys Cys Gly
19970 19975 19980
Gly Cys Thr Ala Cys Cys Thr Cys Gly Cys Ala Cys Cys Cys Ala
19985 19990 19995
Cys Cys Ala Thr Gly Cys Gly Cys Cys Ala Gly Gly Gly Gly Cys
20000 20005 20010
Ala Gly Cys Cys Cys Thr Ala Cys Cys Cys Cys Gly Cys Cys Ala
20015 20020 20025
Ala Cys Thr Thr Cys Cys Cys Cys Thr Ala Cys Cys Cys Gly Cys
20030 20035 20040
Thr Cys Ala Thr Cys Gly Gly Thr Cys Ala Gly Ala Cys Ala Gly
20045 20050 20055
Cys Cys Gly Thr Gly Cys Cys Cys Thr Cys Cys Gly Thr Cys Ala
20060 20065 20070
Cys Cys Cys Ala Gly Ala Ala Ala Ala Ala Gly Thr Thr Cys Cys
20075 20080 20085
Thr Cys Thr Gly Cys Gly Ala Cys Ala Gly Gly Gly Thr Cys Ala
20090 20095 20100
Thr Gly Thr Gly Gly Cys Gly Cys Ala Thr Cys Cys Cys Cys Thr
20105 20110 20115
Thr Cys Thr Cys Cys Ala Gly Cys Ala Ala Cys Thr Thr Cys Ala
20120 20125 20130
Thr Gly Thr Cys Cys Ala Thr Gly Gly Gly Cys Gly Cys Cys Cys
20135 20140 20145
Thr Cys Ala Cys Cys Gly Ala Cys Cys Thr Gly Gly Gly Thr Cys
20150 20155 20160
Ala Gly Ala Ala Cys Ala Thr Gly Cys Thr Cys Thr Ala Cys Gly
20165 20170 20175
Cys Cys Ala Ala Cys Thr Cys Gly Gly Cys Cys Cys Ala Cys Gly
20180 20185 20190
Cys Gly Cys Thr Cys Gly Ala Cys Ala Thr Gly Ala Cys Cys Thr
20195 20200 20205
Thr Cys Gly Ala Gly Gly Thr Gly Gly Ala Cys Cys Cys Cys Ala
20210 20215 20220
Thr Gly Gly Ala Thr Gly Ala Gly Cys Cys Cys Ala Cys Cys Cys
20225 20230 20235
Thr Cys Cys Thr Cys Thr Ala Thr Cys Thr Thr Cys Thr Cys Thr
20240 20245 20250
Thr Cys Gly Ala Ala Gly Thr Thr Thr Thr Cys Gly Ala Cys Gly
20255 20260 20265
Thr Gly Gly Thr Cys Ala Gly Ala Gly Thr Ala Cys Ala Cys Cys
20270 20275 20280
Ala Gly Cys Cys Gly Cys Ala Cys Cys Gly Cys Gly Gly Cys Gly
20285 20290 20295
Thr Cys Ala Thr Cys Gly Ala Gly Gly Cys Cys Gly Thr Cys Thr
20300 20305 20310
Ala Cys Cys Thr Gly Cys Gly Cys Ala Cys Gly Cys Cys Cys Thr
20315 20320 20325
Thr Cys Thr Cys Cys Gly Cys Cys Gly Gly Cys Ala Ala Cys Gly
20330 20335 20340
Cys Cys Ala Cys Cys Ala Cys Cys Thr Ala Ala Gly Cys Ala Thr
20345 20350 20355
Gly Ala Gly Cys Gly Gly Cys Thr Cys Cys Ala Gly Cys Gly Ala
20360 20365 20370
Ala Cys Gly Ala Gly Ala Gly Cys Thr Cys Gly Cys Gly Gly Cys
20375 20380 20385
Cys Ala Thr Cys Gly Thr Gly Cys Gly Cys Gly Ala Cys Cys Thr
20390 20395 20400
Gly Gly Gly Cys Thr Gly Cys Gly Gly Gly Cys Cys Cys Thr Ala
20405 20410 20415
Cys Thr Thr Thr Thr Thr Gly Gly Gly Cys Ala Cys Cys Cys Ala
20420 20425 20430
Cys Gly Ala Cys Ala Ala Gly Cys Gly Cys Thr Thr Cys Cys Cys
20435 20440 20445
Gly Gly Gly Cys Thr Thr Thr Cys Thr Cys Gly Cys Cys Gly Gly
20450 20455 20460
Cys Gly Ala Cys Ala Ala Gly Cys Thr Gly Gly Cys Cys Thr Gly
20465 20470 20475
Cys Gly Cys Cys Ala Thr Cys Gly Thr Cys Ala Ala Cys Ala Cys
20480 20485 20490
Gly Gly Cys Cys Gly Gly Cys Cys Gly Cys Gly Ala Gly Ala Cys
20495 20500 20505
Cys Gly Gly Ala Gly Gly Cys Gly Thr Gly Cys Ala Cys Thr Gly
20510 20515 20520
Gly Cys Thr Cys Gly Cys Cys Thr Thr Cys Gly Gly Cys Thr Gly
20525 20530 20535
Gly Ala Ala Cys Cys Cys Gly Cys Gly Cys Thr Cys Gly Cys Gly
20540 20545 20550
Cys Ala Cys Cys Thr Gly Cys Thr Ala Cys Ala Thr Gly Thr Thr
20555 20560 20565
Cys Gly Ala Cys Cys Cys Cys Thr Thr Thr Gly Gly Gly Thr Thr
20570 20575 20580
Cys Thr Cys Gly Gly Ala Cys Cys Gly Cys Cys Gly Gly Cys Thr
20585 20590 20595
Cys Ala Ala Gly Cys Ala Gly Ala Thr Thr Thr Ala Cys Ala Gly
20600 20605 20610
Cys Thr Thr Cys Gly Ala Gly Thr Ala Cys Gly Ala Gly Gly Cys
20615 20620 20625
Cys Ala Thr Gly Cys Thr Gly Cys Gly Cys Cys Gly Cys Ala Gly
20630 20635 20640
Cys Gly Cys Cys Cys Thr Gly Gly Cys Cys Thr Cys Cys Thr Cys
20645 20650 20655
Gly Cys Cys Cys Gly Ala Cys Cys Gly Cys Thr Gly Thr Cys Thr
20660 20665 20670
Cys Ala Gly Cys Cys Thr Cys Gly Ala Gly Cys Ala Gly Thr Cys
20675 20680 20685
Cys Ala Cys Thr Cys Ala Gly Ala Cys Cys Gly Thr Gly Cys Ala
20690 20695 20700
Gly Gly Gly Gly Cys Cys Cys Gly Ala Cys Thr Cys Cys Gly Cys
20705 20710 20715
Cys Gly Cys Cys Thr Gly Cys Gly Gly Ala Cys Thr Cys Thr Thr
20720 20725 20730
Cys Thr Gly Thr Thr Gly Cys Ala Thr Gly Thr Thr Cys Thr Thr
20735 20740 20745
Gly Cys Ala Thr Gly Cys Cys Thr Thr Cys Gly Thr Gly Cys Ala
20750 20755 20760
Cys Thr Gly Gly Cys Cys Cys Gly Ala Cys Cys Gly Ala Cys Cys
20765 20770 20775
Cys Ala Thr Gly Gly Ala Cys Gly Gly Ala Ala Ala Cys Cys Cys
20780 20785 20790
Cys Ala Cys Cys Ala Thr Gly Ala Ala Cys Thr Thr Gly Cys Thr
20795 20800 20805
Gly Ala Cys Gly Gly Gly Gly Gly Thr Gly Cys Cys Cys Ala Ala
20810 20815 20820
Cys Gly Gly Cys Ala Thr Gly Cys Thr Ala Cys Ala Ala Thr Cys
20825 20830 20835
Gly Cys Cys Ala Cys Ala Gly Gly Thr Gly Cys Thr Gly Cys Cys
20840 20845 20850
Cys Ala Cys Cys Cys Thr Cys Ala Gly Gly Cys Gly Cys Ala Ala
20855 20860 20865
Cys Cys Ala Gly Gly Ala Gly Gly Ala Ala Cys Thr Cys Thr Ala
20870 20875 20880
Cys Cys Gly Cys Thr Thr Cys Cys Thr Cys Gly Cys Gly Cys Gly
20885 20890 20895
Cys Cys Ala Cys Thr Cys Cys Cys Cys Thr Thr Ala Cys Thr Thr
20900 20905 20910
Thr Cys Gly Cys Thr Cys Cys Cys Ala Cys Cys Gly Cys Gly Cys
20915 20920 20925
Cys Gly Cys Cys Ala Thr Cys Gly Ala Ala Cys Ala Cys Gly Cys
20930 20935 20940
Cys Ala Cys Cys Gly Cys Thr Thr Thr Thr Gly Ala Cys Ala Ala
20945 20950 20955
Ala Ala Thr Gly Ala Ala Ala Cys Ala Ala Cys Thr Gly Cys Gly
20960 20965 20970
Thr Gly Thr Ala Thr Cys Thr Cys Ala Ala Thr Ala Ala Ala Cys
20975 20980 20985
Ala Gly Cys Ala Cys Thr Thr Thr Thr Ala Thr Thr Thr Thr Ala
20990 20995 21000
Cys Ala Thr Gly Cys Ala Cys Thr Gly Gly Ala Gly Thr Ala Thr
21005 21010 21015
Ala Thr Gly Cys Ala Ala Gly Thr Thr Ala Thr Thr Thr Ala Ala
21020 21025 21030
Ala Ala Gly Thr Cys Gly Ala Ala Gly Gly Gly Gly Thr Thr Cys
21035 21040 21045
Thr Cys Gly Cys Gly Cys Thr Cys Gly Thr Cys Gly Thr Thr Gly
21050 21055 21060
Thr Gly Cys Gly Cys Cys Gly Cys Gly Cys Thr Gly Gly Gly Gly
21065 21070 21075
Ala Gly Gly Gly Cys Cys Ala Cys Gly Thr Thr Gly Cys Gly Gly
21080 21085 21090
Thr Ala Cys Thr Gly Gly Thr Ala Cys Thr Thr Gly Gly Gly Cys
21095 21100 21105
Thr Gly Cys Cys Ala Cys Thr Thr Gly Ala Ala Cys Thr Cys Gly
21110 21115 21120
Gly Gly Gly Ala Thr Cys Ala Cys Cys Ala Gly Thr Thr Thr Gly
21125 21130 21135
Gly Gly Cys Ala Cys Thr Gly Gly Gly Gly Thr Cys Thr Cys Gly
21140 21145 21150
Gly Gly Gly Ala Ala Gly Gly Thr Cys Thr Cys Gly Cys Thr Cys
21155 21160 21165
Cys Ala Cys Ala Thr Gly Cys Gly Cys Cys Gly Gly Cys Thr Cys
21170 21175 21180
Ala Thr Cys Thr Gly Cys Ala Gly Gly Gly Cys Gly Cys Cys Cys
21185 21190 21195
Ala Gly Cys Ala Thr Gly Thr Cys Cys Gly Gly Gly Gly Cys Gly
21200 21205 21210
Gly Ala Gly Ala Thr Cys Thr Thr Gly Ala Ala Ala Thr Cys Gly
21215 21220 21225
Cys Ala Gly Thr Thr Gly Gly Gly Gly Cys Cys Gly Gly Thr Gly
21230 21235 21240
Cys Thr Cys Thr Gly Cys Gly Cys Gly Cys Gly Cys Gly Ala Gly
21245 21250 21255
Thr Thr Gly Cys Gly Gly Thr Ala Cys Ala Cys Gly Gly Gly Gly
21260 21265 21270
Thr Thr Gly Cys Ala Gly Cys Ala Cys Thr Gly Gly Ala Ala Cys
21275 21280 21285
Ala Cys Cys Ala Thr Cys Ala Gly Ala Cys Thr Gly Gly Gly Gly
21290 21295 21300
Thr Ala Cys Thr Thr Cys Ala Cys Ala Cys Thr Ala Gly Cys Cys
21305 21310 21315
Ala Gly Cys Ala Cys Gly Cys Thr Cys Thr Thr Gly Thr Cys Gly
21320 21325 21330
Cys Thr Gly Ala Thr Cys Thr Gly Ala Thr Cys Cys Thr Thr Gly
21335 21340 21345
Thr Cys Cys Ala Gly Ala Thr Cys Cys Thr Cys Gly Gly Cys Gly
21350 21355 21360
Thr Thr Gly Cys Thr Cys Ala Gly Gly Cys Cys Gly Ala Ala Cys
21365 21370 21375
Gly Gly Gly Gly Thr Cys Ala Thr Cys Thr Thr Gly Cys Ala Cys
21380 21385 21390
Ala Gly Cys Thr Gly Gly Cys Gly Thr Cys Cys Cys Ala Gly Gly
21395 21400 21405
Ala Ala Gly Gly Gly Cys Ala Cys Gly Cys Thr Cys Thr Gly Ala
21410 21415 21420
Gly Gly Cys Thr Thr Gly Thr Gly Gly Thr Thr Ala Cys Ala Cys
21425 21430 21435
Thr Cys Gly Cys Ala Gly Thr Gly Cys Ala Cys Gly Gly Gly Cys
21440 21445 21450
Ala Thr Cys Ala Gly Cys Ala Thr Cys Ala Thr Cys Cys Cys Cys
21455 21460 21465
Gly Cys Gly Cys Cys Gly Cys Gly Cys Thr Gly Cys Ala Thr Ala
21470 21475 21480
Thr Thr Cys Gly Gly Gly Thr Ala Gly Ala Gly Gly Gly Cys Cys
21485 21490 21495
Thr Thr Gly Ala Cys Ala Ala Ala Gly Gly Cys Cys Gly Cys Gly
21500 21505 21510
Ala Thr Cys Thr Gly Cys Thr Thr Gly Ala Ala Ala Gly Cys Thr
21515 21520 21525
Thr Gly Cys Thr Gly Gly Gly Cys Cys Thr Thr Gly Gly Cys Cys
21530 21535 21540
Cys Cys Cys Thr Cys Gly Cys Thr Gly Ala Ala Ala Ala Ala Cys
21545 21550 21555
Ala Gly Gly Cys Cys Gly Cys Ala Gly Cys Thr Cys Thr Thr Cys
21560 21565 21570
Cys Cys Gly Cys Thr Gly Ala Ala Cys Thr Gly Gly Thr Thr Ala
21575 21580 21585
Thr Thr Cys Cys Cys Ala Cys Ala Cys Cys Cys Gly Gly Cys Ala
21590 21595 21600
Thr Cys Cys Thr Gly Cys Ala Cys Gly Cys Ala Gly Cys Ala Gly
21605 21610 21615
Cys Gly Cys Gly Cys Gly Thr Cys Ala Thr Gly Gly Cys Thr Gly
21620 21625 21630
Gly Thr Cys Ala Gly Thr Thr Gly Cys Ala Cys Cys Ala Cys Gly
21635 21640 21645
Cys Thr Cys Cys Gly Thr Cys Cys Cys Cys Ala Gly Cys Gly Gly
21650 21655 21660
Thr Thr Cys Thr Gly Gly Gly Thr Cys Ala Cys Cys Thr Thr Ala
21665 21670 21675
Gly Cys Cys Thr Thr Gly Cys Thr Gly Gly Gly Cys Thr Gly Cys
21680 21685 21690
Thr Cys Cys Thr Thr Cys Ala Ala Cys Gly Cys Gly Cys Gly Cys
21695 21700 21705
Thr Gly Cys Cys Cys Gly Thr Thr Cys Thr Cys Gly Cys Thr Gly
21710 21715 21720
Gly Thr Cys Ala Cys Ala Thr Cys Cys Ala Thr Cys Thr Cys Cys
21725 21730 21735
Ala Cys Cys Ala Cys Gly Thr Gly Gly Thr Cys Cys Thr Thr Gly
21740 21745 21750
Thr Gly Gly Ala Thr Cys Ala Thr Cys Ala Thr Cys Gly Thr Cys
21755 21760 21765
Cys Cys Gly Thr Gly Cys Ala Gly Ala Cys Ala Cys Thr Thr Gly
21770 21775 21780
Ala Gly Cys Thr Gly Gly Cys Cys Thr Thr Cys Cys Ala Cys Cys
21785 21790 21795
Thr Cys Gly Gly Thr Gly Cys Ala Gly Cys Cys Gly Thr Gly Ala
21800 21805 21810
Thr Cys Cys Cys Ala Cys Ala Gly Gly Gly Cys Gly Cys Ala Ala
21815 21820 21825
Cys Cys Gly Gly Thr Gly Cys Ala Cys Thr Cys Cys Cys Ala Gly
21830 21835 21840
Thr Thr Cys Thr Thr Gly Thr Gly Cys Gly Cys Ala Ala Thr Cys
21845 21850 21855
Cys Cys Gly Cys Thr Gly Thr Gly Gly Cys Thr Gly Ala Ala Gly
21860 21865 21870
Ala Thr Gly Thr Ala Ala Cys Cys Thr Thr Gly Cys Ala Ala Cys
21875 21880 21885
Ala Thr Gly Cys Gly Gly Cys Cys Cys Ala Thr Gly Ala Thr Gly
21890 21895 21900
Gly Thr Gly Cys Thr Ala Ala Ala Thr Gly Cys Thr Thr Thr Cys
21905 21910 21915
Thr Gly Gly Gly Thr Gly Gly Thr Gly Ala Ala Gly Gly Thr Cys
21920 21925 21930
Ala Gly Thr Thr Gly Cys Ala Thr Cys Cys Cys Gly Cys Gly Gly
21935 21940 21945
Gly Cys Cys Thr Cys Cys Thr Cys Gly Thr Thr Cys Ala Thr Cys
21950 21955 21960
Cys Ala Gly Gly Thr Cys Thr Gly Gly Cys Ala Cys Ala Thr Cys
21965 21970 21975
Thr Thr Cys Thr Gly Gly Ala Ala Gly Ala Thr Cys Thr Cys Gly
21980 21985 21990
Gly Thr Cys Thr Gly Cys Thr Cys Gly Gly Gly Cys Ala Thr Gly
21995 22000 22005
Ala Gly Cys Thr Thr Gly Thr Ala Ala Gly Cys Ala Thr Cys Gly
22010 22015 22020
Cys Gly Cys Ala Gly Gly Cys Cys Gly Cys Thr Gly Thr Cys Gly
22025 22030 22035
Ala Cys Gly Cys Gly Gly Thr Ala Gly Cys Gly Thr Thr Cys Cys
22040 22045 22050
Ala Thr Cys Ala Gly Cys Ala Cys Gly Thr Thr Cys Ala Thr Gly
22055 22060 22065
Gly Thr Ala Thr Cys Cys Ala Thr Gly Cys Cys Cys Thr Thr Cys
22070 22075 22080
Thr Cys Cys Cys Ala Gly Gly Ala Cys Gly Ala Gly Ala Cys Cys
22085 22090 22095
Ala Gly Ala Gly Gly Cys Ala Gly Ala Cys Thr Cys Ala Gly Ala
22100 22105 22110
Gly Gly Gly Thr Thr Gly Cys Gly Thr Ala Cys Gly Thr Thr Cys
22115 22120 22125
Ala Gly Gly Ala Cys Ala Cys Cys Gly Gly Gly Gly Gly Thr Cys
22130 22135 22140
Gly Cys Gly Gly Gly Cys Thr Cys Gly Ala Cys Gly Ala Thr Gly
22145 22150 22155
Cys Gly Thr Thr Thr Thr Cys Cys Gly Thr Cys Cys Thr Thr Gly
22160 22165 22170
Cys Cys Thr Thr Cys Cys Thr Thr Cys Ala Ala Thr Ala Gly Ala
22175 22180 22185
Ala Cys Cys Gly Gly Cys Gly Gly Cys Thr Gly Gly Cys Thr Gly
22190 22195 22200
Ala Ala Thr Cys Cys Cys Ala Cys Thr Cys Cys Cys Ala Cys Gly
22205 22210 22215
Ala Thr Cys Ala Cys Gly Gly Cys Ala Thr Cys Thr Thr Cys Cys
22220 22225 22230
Thr Gly Gly Gly Gly Cys Ala Thr Cys Thr Cys Thr Thr Cys Gly
22235 22240 22245
Thr Cys Gly Gly Gly Gly Thr Cys Thr Ala Cys Cys Thr Thr Gly
22250 22255 22260
Gly Thr Cys Ala Cys Ala Thr Gly Cys Thr Thr Gly Gly Thr Cys
22265 22270 22275
Thr Thr Thr Cys Thr Gly Gly Cys Thr Thr Gly Cys Thr Thr Cys
22280 22285 22290
Thr Thr Thr Thr Thr Thr Gly Gly Ala Gly Gly Gly Cys Thr Gly
22295 22300 22305
Thr Cys Cys Ala Cys Gly Gly Gly Gly Ala Gly Cys Ala Cys Gly
22310 22315 22320
Thr Cys Cys Thr Cys Cys Thr Cys Gly Gly Ala Ala Gly Ala Cys
22325 22330 22335
Cys Cys Gly Gly Ala Gly Cys Cys Cys Ala Cys Cys Cys Gly Cys
22340 22345 22350
Thr Gly Ala Thr Ala Cys Thr Thr Thr Cys Gly Gly Cys Gly Cys
22355 22360 22365
Thr Thr Gly Gly Thr Gly Gly Gly Cys Ala Gly Ala Gly Gly Ala
22370 22375 22380
Gly Gly Thr Gly Gly Cys Gly Gly Cys Gly Ala Gly Gly Gly Gly
22385 22390 22395
Cys Thr Cys Cys Thr Cys Thr Cys Cys Thr Gly Cys Thr Cys Cys
22400 22405 22410
Gly Gly Cys Gly Gly Ala Thr Ala Gly Cys Gly Cys Gly Cys Cys
22415 22420 22425
Gly Ala Cys Cys Cys Gly Thr Gly Gly Cys Cys Cys Cys Gly Gly
22430 22435 22440
Gly Gly Cys Gly Gly Ala Gly Thr Gly Gly Cys Cys Thr Cys Thr
22445 22450 22455
Cys Gly Gly Cys Cys Cys Ala Thr Gly Ala Ala Cys Cys Gly Gly
22460 22465 22470
Cys Gly Cys Ala Cys Gly Thr Cys Cys Thr Gly Ala Cys Thr Gly
22475 22480 22485
Cys Cys Gly Cys Cys Gly Gly Cys Cys Ala Thr Thr Gly Thr Thr
22490 22495 22500
Thr Cys Cys Thr Ala Gly Gly Gly Gly Ala Ala Gly Ala Thr Gly
22505 22510 22515
Gly Ala Gly Gly Ala Gly Cys Ala Gly Cys Cys Gly Cys Gly Thr
22520 22525 22530
Ala Ala Gly Cys Ala Gly Gly Ala Gly Cys Ala Gly Gly Ala Gly
22535 22540 22545
Gly Ala Gly Gly Ala Cys Thr Thr Ala Ala Cys Cys Ala Cys Cys
22550 22555 22560
Cys Ala Cys Gly Ala Gly Cys Ala Ala Cys Cys Cys Ala Ala Ala
22565 22570 22575
Ala Thr Cys Gly Ala Gly Cys Ala Gly Gly Ala Cys Cys Thr Gly
22580 22585 22590
Gly Gly Cys Thr Thr Cys Gly Ala Ala Gly Ala Gly Cys Cys Gly
22595 22600 22605
Gly Cys Thr Cys Gly Thr Cys Thr Ala Gly Ala Ala Cys Cys Cys
22610 22615 22620
Cys Cys Ala Cys Ala Gly Gly Ala Thr Gly Ala Ala Cys Ala Gly
22625 22630 22635
Gly Ala Gly Cys Ala Cys Gly Ala Gly Cys Ala Ala Gly Ala Cys
22640 22645 22650
Gly Cys Ala Gly Gly Cys Cys Ala Gly Gly Ala Gly Gly Ala Gly
22655 22660 22665
Ala Cys Cys Gly Ala Cys Gly Cys Thr Gly Gly Gly Cys Thr Cys
22670 22675 22680
Gly Ala Gly Cys Ala Thr Gly Gly Cys Thr Ala Cys Cys Thr Gly
22685 22690 22695
Gly Gly Ala Gly Gly Ala Gly Ala Gly Gly Ala Gly Gly Ala Thr
22700 22705 22710
Gly Thr Gly Cys Thr Gly Cys Thr Gly Ala Ala Ala Cys Ala Cys
22715 22720 22725
Cys Thr Gly Cys Ala Gly Cys Gly Cys Cys Ala Gly Thr Cys Cys
22730 22735 22740
Cys Thr Cys Ala Thr Cys Cys Thr Cys Cys Gly Gly Gly Ala Cys
22745 22750 22755
Gly Cys Cys Cys Thr Gly Gly Cys Cys Gly Ala Cys Cys Gly Gly
22760 22765 22770
Ala Gly Cys Gly Ala Ala Ala Cys Cys Cys Cys Cys Cys Thr Cys
22775 22780 22785
Ala Gly Cys Gly Thr Cys Gly Ala Gly Gly Ala Gly Cys Thr Gly
22790 22795 22800
Thr Gly Thr Cys Gly Gly Gly Cys Cys Thr Ala Cys Gly Ala Gly
22805 22810 22815
Cys Thr Cys Ala Ala Cys Cys Thr Cys Thr Thr Cys Thr Cys Gly
22820 22825 22830
Cys Cys Gly Cys Gly Cys Gly Thr Ala Cys Cys Cys Cys Cys Cys
22835 22840 22845
Ala Ala Ala Cys Gly Cys Cys Ala Gly Cys Cys Cys Ala Ala Cys
22850 22855 22860
Gly Gly Cys Ala Cys Cys Thr Gly Cys Gly Ala Gly Cys Cys Cys
22865 22870 22875
Ala Ala Cys Cys Cys Gly Cys Gly Thr Cys Thr Cys Ala Ala Cys
22880 22885 22890
Thr Thr Cys Thr Ala Thr Cys Cys Cys Gly Thr Cys Thr Thr Thr
22895 22900 22905
Gly Cys Gly Gly Thr Cys Cys Cys Cys Gly Ala Ala Gly Cys Cys
22910 22915 22920
Cys Thr Cys Gly Cys Cys Ala Cys Cys Thr Ala Thr Cys Ala Cys
22925 22930 22935
Ala Thr Cys Thr Thr Thr Thr Thr Cys Ala Ala Gly Ala Ala Cys
22940 22945 22950
Cys Ala Ala Ala Ala Gly Ala Thr Cys Cys Cys Cys Gly Thr Cys
22955 22960 22965
Thr Cys Cys Thr Gly Cys Cys Gly Cys Gly Cys Cys Ala Ala Cys
22970 22975 22980
Cys Gly Cys Ala Cys Cys Ala Gly Cys Gly Cys Cys Gly Ala Cys
22985 22990 22995
Gly Cys Gly Cys Thr Cys Cys Thr Cys Gly Cys Thr Thr Thr Gly
23000 23005 23010
Gly Gly Gly Cys Cys Cys Gly Gly Cys Gly Cys Gly Cys Gly Cys
23015 23020 23025
Ala Thr Ala Cys Cys Thr Gly Ala Thr Ala Thr Cys Gly Cys Thr
23030 23035 23040
Thr Cys Cys Cys Thr Gly Gly Ala Ala Gly Ala Gly Gly Thr Gly
23045 23050 23055
Cys Cys Cys Ala Ala Gly Ala Thr Cys Thr Thr Cys Gly Ala Ala
23060 23065 23070
Gly Gly Gly Cys Thr Cys Gly Gly Thr Cys Gly Gly Gly Ala Cys
23075 23080 23085
Gly Ala Gly Ala Cys Gly Cys Gly Cys Gly Cys Gly Gly Cys Gly
23090 23095 23100
Ala Ala Cys Gly Cys Thr Cys Thr Gly Ala Ala Ala Gly Ala Ala
23105 23110 23115
Ala Cys Ala Gly Cys Ala Gly Ala Gly Gly Ala Ala Gly Ala Gly
23120 23125 23130
Gly Gly Thr Cys Ala Cys Ala Cys Thr Ala Gly Cys Gly Cys Cys
23135 23140 23145
Cys Thr Gly Gly Thr Ala Gly Ala Gly Thr Thr Gly Gly Ala Ala
23150 23155 23160
Gly Gly Cys Gly Ala Cys Ala Ala Cys Gly Cys Cys Ala Gly Gly
23165 23170 23175
Cys Thr Gly Gly Cys Cys Gly Thr Gly Cys Thr Cys Ala Ala Gly
23180 23185 23190
Cys Gly Cys Ala Gly Cys Gly Thr Cys Gly Ala Gly Cys Thr Thr
23195 23200 23205
Ala Cys Cys Cys Ala Cys Thr Thr Cys Gly Cys Cys Thr Ala Cys
23210 23215 23220
Cys Cys Cys Gly Cys Cys Gly Thr Cys Ala Ala Cys Cys Thr Cys
23225 23230 23235
Cys Cys Gly Cys Cys Cys Ala Ala Gly Gly Thr Cys Ala Thr Gly
23240 23245 23250
Cys Gly Thr Cys Gly Cys Ala Thr Cys Ala Thr Gly Gly Ala Thr
23255 23260 23265
Cys Ala Gly Cys Thr Cys Ala Thr Cys Ala Thr Gly Cys Cys Cys
23270 23275 23280
Cys Ala Cys Ala Thr Cys Gly Ala Gly Gly Cys Cys Cys Thr Cys
23285 23290 23295
Gly Ala Thr Gly Ala Ala Ala Gly Thr Cys Ala Gly Gly Ala Gly
23300 23305 23310
Cys Ala Gly Cys Gly Cys Cys Cys Cys Gly Ala Gly Gly Ala Cys
23315 23320 23325
Gly Cys Cys Cys Gly Gly Cys Cys Cys Gly Thr Gly Gly Thr Cys
23330 23335 23340
Ala Gly Cys Gly Ala Cys Gly Ala Gly Ala Thr Gly Cys Thr Cys
23345 23350 23355
Gly Cys Gly Cys Gly Cys Thr Gly Gly Cys Thr Cys Gly Gly Gly
23360 23365 23370
Ala Cys Cys Cys Gly Cys Gly Ala Cys Cys Cys Cys Cys Ala Gly
23375 23380 23385
Gly Cys Thr Thr Thr Gly Gly Ala Ala Cys Ala Gly Cys Gly Gly
23390 23395 23400
Cys Gly Cys Ala Ala Ala Cys Thr Cys Ala Thr Gly Cys Thr Gly
23405 23410 23415
Gly Cys Cys Gly Thr Gly Gly Thr Cys Cys Thr Gly Gly Thr Cys
23420 23425 23430
Ala Cys Cys Cys Thr Thr Gly Ala Gly Cys Thr Cys Gly Ala Ala
23435 23440 23445
Thr Gly Cys Ala Thr Gly Cys Gly Cys Cys Gly Cys Thr Thr Thr
23450 23455 23460
Thr Thr Cys Ala Gly Cys Gly Ala Cys Cys Cys Cys Gly Ala Gly
23465 23470 23475
Ala Cys Cys Cys Thr Gly Cys Gly Cys Ala Ala Gly Gly Thr Cys
23480 23485 23490
Gly Ala Gly Gly Ala Gly Ala Cys Cys Cys Thr Gly Cys Ala Cys
23495 23500 23505
Thr Ala Cys Ala Cys Thr Thr Thr Cys Ala Gly Gly Cys Ala Cys
23510 23515 23520
Gly Gly Thr Thr Thr Cys Gly Thr Cys Ala Gly Gly Cys Ala Gly
23525 23530 23535
Gly Cys Cys Thr Gly Cys Ala Ala Gly Ala Thr Cys Thr Cys Cys
23540 23545 23550
Ala Ala Cys Gly Thr Gly Gly Ala Gly Cys Thr Gly Ala Cys Cys
23555 23560 23565
Ala Ala Cys Cys Thr Gly Gly Thr Cys Thr Cys Cys Thr Gly Cys
23570 23575 23580
Cys Thr Gly Gly Gly Gly Ala Thr Cys Cys Thr Gly Cys Ala Cys
23585 23590 23595
Gly Ala Gly Ala Ala Cys Cys Gly Cys Cys Thr Gly Gly Gly Cys
23600 23605 23610
Cys Ala Gly Ala Cys Cys Gly Thr Gly Cys Thr Cys Cys Ala Cys
23615 23620 23625
Thr Cys Thr Ala Cys Cys Cys Thr Gly Ala Ala Gly Gly Gly Cys
23630 23635 23640
Gly Ala Gly Gly Cys Gly Cys Gly Gly Cys Gly Gly Gly Ala Cys
23645 23650 23655
Thr Ala Thr Gly Thr Cys Cys Gly Cys Gly Ala Cys Thr Gly Cys
23660 23665 23670
Gly Thr Cys Thr Thr Thr Cys Thr Cys Thr Thr Thr Cys Thr Cys
23675 23680 23685
Thr Gly Cys Cys Ala Cys Ala Cys Ala Thr Gly Gly Cys Ala Ala
23690 23695 23700
Gly Cys Gly Gly Cys Cys Ala Thr Gly Gly Gly Cys Gly Thr Gly
23705 23710 23715
Thr Gly Gly Cys Ala Gly Cys Ala Gly Thr Gly Thr Cys Thr Cys
23720 23725 23730
Gly Ala Gly Gly Ala Cys Gly Ala Gly Ala Ala Cys Cys Thr Ala
23735 23740 23745
Ala Ala Gly Gly Ala Gly Cys Thr Gly Gly Ala Cys Ala Ala Gly
23750 23755 23760
Cys Thr Thr Cys Thr Thr Gly Cys Thr Ala Gly Ala Ala Ala Cys
23765 23770 23775
Cys Thr Thr Ala Ala Ala Ala Ala Gly Cys Thr Gly Thr Gly Gly
23780 23785 23790
Ala Cys Gly Gly Gly Cys Thr Thr Cys Gly Ala Cys Gly Ala Gly
23795 23800 23805
Cys Gly Cys Ala Cys Cys Gly Thr Cys Gly Cys Cys Thr Cys Gly
23810 23815 23820
Gly Ala Cys Cys Thr Gly Gly Cys Cys Gly Ala Gly Ala Thr Cys
23825 23830 23835
Gly Thr Cys Thr Thr Cys Cys Cys Cys Gly Ala Gly Cys Gly Cys
23840 23845 23850
Cys Thr Gly Ala Gly Ala Cys Ala Gly Ala Cys Gly Cys Thr Gly
23855 23860 23865
Ala Ala Ala Gly Gly Cys Gly Gly Gly Cys Thr Gly Cys Cys Cys
23870 23875 23880
Gly Ala Cys Thr Thr Cys Ala Thr Gly Ala Gly Cys Cys Ala Gly
23885 23890 23895
Ala Gly Cys Ala Thr Gly Thr Thr Gly Cys Ala Ala Ala Ala Cys
23900 23905 23910
Thr Ala Cys Cys Gly Cys Ala Cys Thr Thr Thr Cys Ala Thr Thr
23915 23920 23925
Cys Thr Thr Gly Ala Gly Cys Gly Ala Thr Cys Ala Gly Gly Cys
23930 23935 23940
Ala Thr Cys Cys Thr Gly Cys Cys Cys Gly Cys Cys Ala Cys Cys
23945 23950 23955
Thr Gly Cys Ala Ala Cys Gly Cys Cys Thr Thr Cys Cys Cys Cys
23960 23965 23970
Thr Cys Cys Gly Ala Cys Thr Thr Thr Gly Thr Ala Cys Cys Gly
23975 23980 23985
Cys Thr Gly Ala Gly Cys Thr Ala Cys Cys Gly Cys Gly Ala Gly
23990 23995 24000
Thr Gly Thr Cys Cys Cys Cys Cys Gly Cys Cys Gly Cys Thr Gly
24005 24010 24015
Thr Gly Gly Ala Gly Cys Cys Ala Cys Thr Gly Cys Thr Ala Cys
24020 24025 24030
Cys Thr Cys Thr Thr Gly Cys Ala Gly Cys Thr Gly Gly Cys Cys
24035 24040 24045
Ala Ala Cys Thr Ala Cys Ala Thr Cys Gly Cys Cys Thr Ala Cys
24050 24055 24060
Cys Ala Cys Thr Cys Gly Gly Ala Cys Gly Thr Gly Ala Thr Cys
24065 24070 24075
Gly Ala Gly Gly Ala Cys Gly Thr Gly Ala Gly Cys Gly Gly Cys
24080 24085 24090
Gly Ala Gly Gly Gly Gly Cys Thr Gly Cys Thr Cys Gly Ala Gly
24095 24100 24105
Thr Gly Cys Cys Ala Cys Thr Gly Thr Cys Gly Cys Thr Gly Cys
24110 24115 24120
Ala Ala Cys Cys Thr Gly Thr Gly Cys Thr Cys Cys Cys Cys Gly
24125 24130 24135
Cys Ala Thr Cys Gly Cys Thr Cys Cys Cys Thr Gly Gly Thr Cys
24140 24145 24150
Thr Gly Cys Ala Ala Cys Cys Cys Cys Cys Ala Gly Cys Thr Cys
24155 24160 24165
Cys Thr Gly Ala Gly Cys Gly Ala Gly Ala Cys Cys Cys Ala Gly
24170 24175 24180
Gly Thr Cys Ala Thr Cys Gly Gly Thr Ala Cys Cys Thr Thr Cys
24185 24190 24195
Gly Ala Gly Cys Thr Gly Cys Ala Ala Gly Gly Thr Cys Cys Gly
24200 24205 24210
Cys Ala Gly Gly Ala Gly Thr Cys Cys Ala Cys Cys Gly Cys Thr
24215 24220 24225
Cys Cys Gly Cys Thr Gly Ala Ala Ala Cys Thr Cys Ala Cys Gly
24230 24235 24240
Cys Cys Gly Gly Gly Gly Thr Thr Gly Thr Gly Gly Ala Cys Thr
24245 24250 24255
Thr Cys Cys Gly Cys Gly Thr Ala Cys Cys Thr Gly Cys Gly Cys
24260 24265 24270
Ala Ala Ala Thr Thr Thr Gly Thr Ala Cys Cys Cys Gly Ala Ala
24275 24280 24285
Gly Ala Cys Thr Ala Cys Cys Ala Cys Gly Cys Cys Cys Ala Thr
24290 24295 24300
Gly Ala Gly Ala Thr Ala Ala Ala Gly Thr Thr Cys Thr Thr Thr
24305 24310 24315
Gly Ala Gly Gly Ala Cys Cys Ala Ala Thr Cys Gly Cys Gly Thr
24320 24325 24330
Cys Cys Gly Cys Ala Gly Cys Ala Cys Gly Cys Gly Gly Ala Thr
24335 24340 24345
Cys Thr Cys Ala Cys Gly Gly Cys Cys Thr Gly Cys Gly Thr Cys
24350 24355 24360
Ala Thr Cys Ala Cys Cys Cys Ala Gly Gly Gly Cys Gly Cys Gly
24365 24370 24375
Ala Thr Cys Cys Thr Cys Gly Cys Cys Cys Ala Ala Thr Thr Gly
24380 24385 24390
Cys Ala Cys Gly Cys Cys Ala Thr Cys Cys Ala Ala Ala Ala Ala
24395 24400 24405
Thr Cys Cys Cys Gly Cys Cys Ala Ala Gly Ala Gly Thr Thr Thr
24410 24415 24420
Cys Thr Thr Cys Thr Gly Ala Ala Ala Ala Ala Gly Gly Gly Thr
24425 24430 24435
Ala Gly Ala Gly Gly Gly Gly Thr Cys Thr Ala Cys Cys Thr Gly
24440 24445 24450
Gly Ala Cys Cys Cys Cys Cys Ala Gly Ala Cys Gly Gly Gly Cys
24455 24460 24465
Gly Ala Gly Gly Thr Gly Cys Thr Cys Ala Ala Cys Cys Cys Gly
24470 24475 24480
Gly Gly Thr Cys Thr Cys Cys Cys Cys Cys Ala Gly Cys Ala Thr
24485 24490 24495
Gly Cys Cys Gly Ala Gly Gly Ala Ala Gly Ala Ala Gly Cys Ala
24500 24505 24510
Gly Gly Ala Gly Cys Cys Gly Cys Thr Ala Gly Thr Gly Gly Ala
24515 24520 24525
Gly Gly Ala Gly Ala Thr Gly Gly Ala Ala Gly Ala Ala Gly Ala
24530 24535 24540
Ala Thr Gly Gly Gly Ala Cys Ala Gly Cys Cys Ala Gly Gly Cys
24545 24550 24555
Ala Gly Ala Gly Gly Ala Gly Gly Ala Cys Gly Ala Ala Thr Gly
24560 24565 24570
Gly Gly Ala Gly Gly Ala Gly Gly Ala Gly Ala Cys Ala Gly Ala
24575 24580 24585
Gly Gly Ala Gly Gly Ala Ala Gly Ala Ala Thr Thr Gly Gly Ala
24590 24595 24600
Ala Gly Ala Gly Gly Thr Gly Gly Ala Ala Gly Ala Gly Gly Ala
24605 24610 24615
Gly Cys Ala Gly Gly Cys Ala Ala Cys Ala Gly Ala Gly Cys Ala
24620 24625 24630
Gly Cys Cys Cys Gly Thr Cys Gly Cys Cys Gly Cys Ala Cys Cys
24635 24640 24645
Ala Thr Cys Cys Gly Cys Gly Cys Cys Gly Gly Cys Ala Gly Cys
24650 24655 24660
Cys Cys Cys Gly Cys Cys Gly Gly Thr Cys Ala Cys Gly Gly Ala
24665 24670 24675
Thr Ala Cys Ala Ala Cys Cys Thr Cys Cys Gly Cys Thr Cys Cys
24680 24685 24690
Gly Gly Thr Cys Ala Ala Gly Cys Cys Thr Cys Cys Thr Cys Gly
24695 24700 24705
Thr Ala Gly Ala Thr Gly Gly Gly Ala Thr Cys Ala Ala Gly Thr
24710 24715 24720
Gly Ala Ala Gly Gly Gly Thr Gly Ala Cys Gly Gly Thr Ala Ala
24725 24730 24735
Gly Cys Ala Cys Gly Ala Gly Cys Gly Gly Cys Ala Gly Gly Gly
24740 24745 24750
Cys Thr Ala Cys Cys Gly Ala Thr Cys Ala Thr Gly Gly Ala Gly
24755 24760 24765
Gly Gly Cys Cys Cys Ala Cys Ala Ala Ala Gly Cys Cys Gly Cys
24770 24775 24780
Gly Ala Thr Cys Ala Thr Cys Gly Cys Cys Thr Gly Cys Thr Thr
24785 24790 24795
Gly Cys Ala Ala Gly Ala Cys Thr Gly Cys Gly Gly Gly Gly Gly
24800 24805 24810
Gly Ala Ala Cys Ala Thr Cys Gly Cys Thr Thr Thr Cys Gly Cys
24815 24820 24825
Cys Cys Gly Cys Cys Gly Cys Thr Ala Cys Cys Thr Gly Cys Thr
24830 24835 24840
Cys Thr Thr Cys Cys Ala Cys Cys Gly Cys Gly Gly Gly Gly Thr
24845 24850 24855
Gly Ala Ala Cys Ala Thr Cys Cys Cys Cys Cys Gly Cys Ala Ala
24860 24865 24870
Cys Gly Thr Gly Thr Thr Gly Cys Ala Thr Thr Ala Cys Thr Ala
24875 24880 24885
Cys Cys Gly Thr Cys Ala Cys Cys Thr Thr Cys Ala Cys Ala Gly
24890 24895 24900
Cys Thr Ala Ala Gly Ala Ala Ala Ala Ala Gly Cys Ala Ala Gly
24905 24910 24915
Thr Cys Ala Ala Ala Gly Gly Ala Gly Thr Cys Gly Cys Cys Gly
24920 24925 24930
Gly Ala Gly Gly Ala Gly Gly Ala Gly Gly Ala Gly Gly Ala Gly
24935 24940 24945
Gly Cys Cys Thr Gly Ala Gly Gly Ala Thr Cys Gly Cys Gly Gly
24950 24955 24960
Cys Gly Ala Ala Cys Gly Ala Gly Cys Cys Cys Thr Thr Gly Ala
24965 24970 24975
Cys Cys Ala Cys Cys Ala Gly Gly Gly Ala Gly Cys Thr Gly Ala
24980 24985 24990
Gly Gly Ala Ala Cys Cys Gly Gly Ala Thr Cys Thr Thr Cys Cys
24995 25000 25005
Cys Cys Ala Cys Thr Cys Thr Thr Thr Ala Thr Gly Cys Cys Ala
25010 25015 25020
Thr Thr Thr Thr Thr Cys Ala Gly Cys Ala Gly Ala Gly Thr Cys
25025 25030 25035
Gly Ala Gly Gly Thr Cys Ala Gly Cys Ala Gly Cys Ala Ala Gly
25040 25045 25050
Ala Gly Cys Thr Cys Ala Ala Ala Gly Thr Ala Ala Ala Ala Ala
25055 25060 25065
Ala Cys Cys Gly Gly Thr Cys Thr Cys Thr Gly Cys Gly Cys Thr
25070 25075 25080
Cys Gly Cys Thr Cys Ala Cys Cys Cys Gly Cys Ala Gly Thr Thr
25085 25090 25095
Gly Cys Thr Thr Gly Thr Ala Cys Cys Ala Cys Ala Ala Ala Ala
25100 25105 25110
Ala Cys Gly Ala Ala Gly Ala Thr Cys Ala Gly Cys Thr Gly Cys
25115 25120 25125
Ala Gly Cys Gly Cys Ala Cys Thr Cys Thr Cys Gly Ala Ala Gly
25130 25135 25140
Ala Cys Gly Cys Cys Gly Ala Gly Gly Cys Thr Cys Thr Gly Thr
25145 25150 25155
Thr Cys Cys Ala Cys Ala Ala Gly Thr Ala Cys Thr Gly Cys Gly
25160 25165 25170
Cys Gly Cys Thr Cys Ala Cys Thr Cys Thr Thr Ala Ala Ala Gly
25175 25180 25185
Ala Cys Thr Ala Ala Gly Gly Cys Gly Cys Gly Cys Cys Cys Ala
25190 25195 25200
Cys Cys Cys Gly Gly Ala Ala Ala Ala Ala Ala Gly Gly Cys Gly
25205 25210 25215
Gly Gly Ala Ala Thr Thr Ala Cys Cys Thr Cys Ala Thr Cys Gly
25220 25225 25230
Cys Cys Ala Cys Cys Ala Thr Gly Ala Gly Cys Ala Ala Gly Gly
25235 25240 25245
Ala Gly Ala Thr Thr Cys Cys Cys Ala Cys Cys Cys Cys Thr Thr
25250 25255 25260
Ala Cys Ala Thr Gly Thr Gly Gly Ala Gly Cys Thr Ala Thr Cys
25265 25270 25275
Ala Gly Cys Cys Cys Cys Ala Ala Ala Thr Gly Gly Gly Cys Cys
25280 25285 25290
Thr Gly Gly Cys Cys Gly Cys Gly Gly Gly Cys Gly Cys Cys Thr
25295 25300 25305
Cys Cys Cys Ala Gly Gly Ala Cys Thr Ala Cys Thr Cys Cys Ala
25310 25315 25320
Cys Cys Cys Gly Cys Ala Thr Gly Ala Ala Cys Thr Gly Gly Cys
25325 25330 25335
Thr Cys Ala Gly Thr Gly Cys Cys Gly Gly Cys Cys Cys Cys Thr
25340 25345 25350
Cys Gly Ala Thr Gly Ala Thr Cys Thr Cys Ala Cys Gly Gly Gly
25355 25360 25365
Thr Cys Ala Ala Cys Gly Gly Gly Gly Thr Cys Cys Gly Cys Ala
25370 25375 25380
Gly Thr Cys Ala Thr Cys Gly Ala Ala Ala Cys Cys Ala Gly Ala
25385 25390 25395
Thr Ala Thr Thr Gly Thr Thr Gly Gly Ala Gly Cys Ala Gly Gly
25400 25405 25410
Cys Gly Gly Cys Gly Gly Thr Cys Ala Cys Cys Thr Cys Cys Ala
25415 25420 25425
Cys Gly Cys Cys Cys Ala Gly Gly Gly Cys Ala Ala Ala Gly Cys
25430 25435 25440
Thr Cys Ala Ala Cys Cys Cys Gly Cys Gly Thr Ala Ala Thr Thr
25445 25450 25455
Gly Gly Cys Cys Cys Thr Cys Cys Ala Cys Cys Cys Thr Gly Gly
25460 25465 25470
Thr Gly Thr Ala Thr Cys Ala Gly Gly Ala Ala Ala Thr Cys Cys
25475 25480 25485
Cys Cys Gly Gly Gly Cys Cys Gly Ala Cys Thr Ala Cys Cys Gly
25490 25495 25500
Thr Ala Cys Thr Ala Cys Thr Thr Cys Cys Gly Cys Gly Thr Gly
25505 25510 25515
Ala Cys Gly Cys Ala Cys Thr Gly Gly Cys Cys Gly Ala Ala Gly
25520 25525 25530
Thr Cys Cys Gly Cys Ala Thr Gly Ala Cys Thr Ala Ala Cys Thr
25535 25540 25545
Cys Ala Gly Gly Thr Gly Thr Cys Cys Ala Gly Cys Thr Gly Gly
25550 25555 25560
Cys Cys Gly Gly Cys Gly Gly Cys Gly Cys Thr Thr Cys Cys Cys
25565 25570 25575
Gly Gly Thr Gly Cys Cys Cys Gly Cys Thr Cys Cys Gly Cys Cys
25580 25585 25590
Cys Ala Cys Ala Ala Thr Cys Gly Gly Gly Thr Ala Thr Ala Ala
25595 25600 25605
Ala Ala Ala Cys Cys Cys Thr Gly Gly Thr Gly Ala Thr Cys Cys
25610 25615 25620
Gly Ala Gly Gly Cys Ala Gly Ala Gly Gly Cys Ala Cys Ala Cys
25625 25630 25635
Ala Gly Cys Thr Cys Ala Ala Cys Gly Ala Cys Gly Ala Gly Thr
25640 25645 25650
Thr Gly Gly Thr Gly Ala Gly Cys Thr Cys Thr Thr Cys Gly Ala
25655 25660 25665
Thr Cys Gly Gly Thr Cys Thr Gly Cys Gly Ala Cys Cys Gly Gly
25670 25675 25680
Ala Cys Gly Gly Ala Gly Thr Gly Thr Thr Cys Cys Ala Ala Cys
25685 25690 25695
Thr Ala Gly Cys Cys Gly Gly Ala Gly Cys Cys Gly Gly Gly Ala
25700 25705 25710
Gly Ala Thr Cys Cys Thr Cys Cys Thr Thr Cys Ala Cys Thr Cys
25715 25720 25725
Cys Cys Ala Ala Cys Cys Ala Gly Gly Cys Cys Thr Ala Cys Cys
25730 25735 25740
Thr Gly Ala Cys Cys Thr Thr Gly Cys Ala Gly Ala Gly Cys Ala
25745 25750 25755
Gly Cys Thr Cys Thr Thr Cys Gly Gly Ala Gly Cys Cys Thr Cys
25760 25765 25770
Gly Cys Thr Cys Cys Gly Gly Ala Gly Gly Cys Ala Thr Cys Gly
25775 25780 25785
Gly Ala Ala Cys Cys Cys Thr Cys Cys Ala Gly Thr Thr Thr Gly
25790 25795 25800
Thr Gly Gly Ala Gly Gly Ala Gly Thr Thr Thr Gly Thr Gly Cys
25805 25810 25815
Cys Cys Thr Cys Gly Gly Thr Cys Thr Ala Cys Thr Thr Cys Ala
25820 25825 25830
Ala Cys Cys Cys Cys Thr Thr Cys Thr Cys Gly Gly Gly Ala Thr
25835 25840 25845
Cys Gly Cys Cys Ala Gly Gly Cys Cys Thr Cys Thr Ala Cys Cys
25850 25855 25860
Cys Gly Gly Ala Cys Gly Ala Gly Thr Thr Cys Ala Thr Ala Cys
25865 25870 25875
Cys Gly Ala Ala Cys Thr Thr Cys Gly Ala Cys Gly Cys Ala Gly
25880 25885 25890
Thr Gly Ala Gly Ala Gly Ala Ala Gly Cys Gly Gly Thr Gly Gly
25895 25900 25905
Ala Cys Gly Gly Cys Thr Ala Cys Gly Ala Cys Thr Gly Ala Ala
25910 25915 25920
Thr Gly Thr Cys Cys Cys Ala Thr Gly Gly Thr Gly Ala Cys Thr
25925 25930 25935
Cys Gly Gly Cys Thr Gly Ala Gly Cys Thr Cys Gly Cys Thr Cys
25940 25945 25950
Gly Gly Thr Thr Gly Ala Gly Gly Cys Ala Thr Cys Thr Gly Gly
25955 25960 25965
Ala Cys Cys Ala Cys Thr Gly Cys Cys Gly Cys Cys Gly Cys Cys
25970 25975 25980
Thr Gly Cys Gly Cys Thr Gly Cys Thr Thr Cys Gly Cys Cys Cys
25985 25990 25995
Gly Gly Gly Ala Gly Ala Gly Cys Thr Gly Cys Gly Gly Ala Cys
26000 26005 26010
Thr Cys Ala Thr Cys Thr Ala Cys Thr Thr Thr Gly Ala Gly Thr
26015 26020 26025
Thr Thr Cys Cys Cys Gly Ala Gly Gly Ala Gly Cys Ala Cys Cys
26030 26035 26040
Cys Cys Ala Ala Cys Gly Gly Cys Cys Cys Thr Gly Cys Ala Cys
26045 26050 26055
Ala Cys Gly Gly Ala Gly Thr Gly Cys Gly Gly Ala Thr Cys Ala
26060 26065 26070
Cys Cys Gly Thr Ala Gly Ala Gly Gly Gly Cys Ala Cys Cys Ala
26075 26080 26085
Cys Cys Gly Ala Gly Thr Cys Thr Cys Ala Cys Cys Thr Gly Gly
26090 26095 26100
Thr Cys Ala Gly Gly Thr Thr Cys Thr Thr Cys Ala Cys Cys Cys
26105 26110 26115
Ala Gly Cys Ala Ala Cys Cys Cys Thr Thr Cys Cys Thr Gly Gly
26120 26125 26130
Thr Cys Gly Ala Gly Cys Gly Gly Gly Ala Cys Cys Gly Gly Gly
26135 26140 26145
Gly Cys Gly Cys Cys Ala Cys Cys Ala Cys Cys Thr Ala Cys Ala
26150 26155 26160
Cys Cys Gly Thr Cys Thr Ala Cys Thr Gly Cys Ala Thr Cys Thr
26165 26170 26175
Gly Thr Cys Cys Ala Ala Cys Cys Cys Cys Gly Ala Ala Gly Thr
26180 26185 26190
Thr Gly Cys Ala Thr Gly Ala Gly Ala Ala Thr Thr Thr Thr Thr
26195 26200 26205
Gly Thr Thr Gly Thr Ala Cys Thr Cys Thr Thr Thr Gly Thr Gly
26210 26215 26220
Gly Thr Gly Ala Gly Thr Thr Thr Ala Ala Thr Ala Ala Ala Ala
26225 26230 26235
Gly Cys Thr Ala Ala Ala Cys Thr Cys Thr Thr Gly Cys Ala Ala
26240 26245 26250
Thr Ala Cys Thr Cys Thr Gly Gly Ala Cys Cys Thr Thr Gly Thr
26255 26260 26265
Cys Gly Thr Cys Gly Thr Cys Ala Ala Cys Thr Cys Ala Ala Cys
26270 26275 26280
Gly Ala Gly Ala Cys Cys Gly Thr Cys Thr Ala Cys Cys Thr Cys
26285 26290 26295
Ala Cys Cys Ala Ala Cys Cys Ala Gly Ala Cys Thr Gly Ala Gly
26300 26305 26310
Gly Thr Ala Ala Ala Ala Cys Thr Cys Ala Cys Cys Thr Gly Cys
26315 26320 26325
Ala Gly Ala Cys Cys Ala Cys Ala Cys Ala Ala Gly Ala Cys Cys
26330 26335 26340
Thr Ala Thr Ala Thr Cys Ala Thr Cys Thr Gly Gly Thr Thr Cys
26345 26350 26355
Thr Thr Cys Gly Ala Gly Ala Ala Cys Ala Cys Cys Thr Cys Ala
26360 26365 26370
Thr Thr Thr Gly Cys Ala Gly Thr Cys Thr Cys Cys Ala Ala Cys
26375 26380 26385
Ala Cys Thr Cys Ala Cys Thr Gly Cys Ala Cys Thr Ala Gly Thr
26390 26395 26400
Cys Cys Ala Thr Gly Ala Ala Cys Thr Gly Ala Thr Gly Thr Thr
26405 26410 26415
Gly Ala Thr Thr Ala Ala Ala Ala Gly Cys Cys Cys Ala Ala Ala
26420 26425 26430
Ala Ala Cys Cys Ala Ala Thr Cys Ala Gly Cys Cys Cys Cys Thr
26435 26440 26445
Thr Cys Cys Cys Cys Cys Ala Thr Thr Thr Cys Cys Cys Cys Ala
26450 26455 26460
Thr Cys Cys Cys Cys Cys Ala Ala Thr Thr Ala Cys Thr Cys Ala
26465 26470 26475
Thr Ala Ala Ala Ala Ala Ala Thr Ala Ala Ala Thr Cys Ala Thr
26480 26485 26490
Thr Gly Gly Ala Ala Thr Thr Ala Ala Thr Cys Ala Thr Thr Cys
26495 26500 26505
Ala Ala Thr Ala Ala Ala Gly Ala Thr Cys Ala Cys Thr Thr Ala
26510 26515 26520
Cys Thr Thr Gly Ala Ala Ala Thr Cys Thr Gly Ala Ala Ala Gly
26525 26530 26535
Thr Ala Thr Gly Thr Cys Thr Cys Thr Gly Gly Thr Gly Thr Ala
26540 26545 26550
Gly Thr Thr Gly Thr Thr Cys Ala Gly Cys Ala Gly Cys Ala Cys
26555 26560 26565
Cys Thr Cys Gly Gly Thr Ala Cys Cys Cys Thr Cys Cys Thr Cys
26570 26575 26580
Cys Cys Ala Gly Cys Thr Cys Thr Gly Gly Thr Ala Cys Thr Cys
26585 26590 26595
Cys Ala Gly Thr Cys Cys Cys Cys Gly Gly Cys Gly Gly Gly Cys
26600 26605 26610
Gly Gly Cys Gly Ala Ala Cys Thr Thr Cys Cys Thr Cys Cys Ala
26615 26620 26625
Cys Ala Cys Cys Thr Thr Gly Ala Ala Ala Gly Gly Gly Ala Thr
26630 26635 26640
Gly Thr Cys Ala Ala Ala Thr Thr Cys Cys Thr Gly Gly Thr Cys
26645 26650 26655
Cys Ala Cys Ala Ala Thr Thr Thr Thr Cys Ala Thr Thr Gly Thr
26660 26665 26670
Cys Thr Thr Cys Cys Cys Thr Cys Thr Cys Ala Gly Ala Thr Gly
26675 26680 26685
Gly Cys Ala Ala Ala Gly Ala Gly Gly Cys Thr Cys Cys Gly Gly
26690 26695 26700
Gly Thr Gly Gly Ala Ala Gly Ala Thr Gly Ala Cys Thr Thr Cys
26705 26710 26715
Ala Ala Cys Cys Cys Cys Gly Thr Cys Thr Ala Cys Cys Cys Cys
26720 26725 26730
Thr Ala Thr Gly Gly Cys Thr Ala Cys Gly Cys Gly Cys Gly Gly
26735 26740 26745
Ala Ala Thr Cys Ala Gly Ala Ala Thr Ala Thr Cys Cys Cys Cys
26750 26755 26760
Thr Thr Cys Cys Thr Cys Ala Cys Thr Cys Cys Cys Cys Cys Cys
26765 26770 26775
Thr Thr Thr Gly Thr Cys Thr Cys Cys Thr Cys Cys Gly Ala Thr
26780 26785 26790
Gly Gly Ala Thr Thr Cys Ala Ala Ala Ala Ala Cys Thr Thr Cys
26795 26800 26805
Cys Cys Cys Cys Cys Thr Gly Gly Gly Gly Thr Cys Cys Thr Gly
26810 26815 26820
Thr Cys Ala Cys Thr Thr Ala Ala Ala Cys Thr Gly Gly Cys Thr
26825 26830 26835
Gly Ala Thr Cys Cys Ala Ala Thr Cys Ala Cys Cys Ala Thr Cys
26840 26845 26850
Ala Ala Cys Ala Ala Thr Gly Gly Gly Gly Ala Thr Gly Thr Cys
26855 26860 26865
Thr Cys Ala Cys Thr Thr Ala Ala Gly Gly Thr Gly Gly Gly Ala
26870 26875 26880
Gly Gly Gly Gly Gly Ala Cys Thr Thr Gly Cys Thr Gly Thr Ala
26885 26890 26895
Gly Ala Gly Cys Ala Ala Cys Ala Gly Ala Cys Thr Gly Gly Thr
26900 26905 26910
Ala Ala Cys Cys Thr Ala Ala Gly Cys Gly Thr Ala Ala Ala Cys
26915 26920 26925
Cys Cys Thr Gly Ala Thr Gly Cys Ala Cys Cys Cys Thr Thr Gly
26930 26935 26940
Cys Ala Ala Gly Thr Thr Gly Cys Ala Ala Gly Thr Gly Ala Thr
26945 26950 26955
Ala Ala Gly Cys Thr Ala Cys Ala Gly Cys Thr Thr Gly Cys Thr
26960 26965 26970
Cys Thr Gly Gly Cys Thr Cys Cys Thr Cys Cys Ala Thr Thr Cys
26975 26980 26985
Gly Ala Gly Gly Thr Cys Ala Gly Ala Gly Ala Thr Gly Gly Ala
26990 26995 27000
Ala Ala Gly Cys Thr Thr Gly Cys Thr Thr Thr Ala Ala Ala Gly
27005 27010 27015
Gly Cys Ala Gly Gly Thr Ala Ala Thr Gly Gly Ala Thr Thr Ala
27020 27025 27030
Ala Ala Ala Gly Thr Ala Cys Thr Ala Gly Ala Thr Ala Ala Thr
27035 27040 27045
Thr Cys Cys Ala Thr Thr Ala Cys Thr Gly Gly Ala Thr Thr Gly
27050 27055 27060
Ala Cys Thr Gly Gly Ala Thr Thr Ala Thr Thr Gly Ala Ala Thr
27065 27070 27075
Ala Cys Ala Cys Thr Thr Gly Thr Gly Gly Thr Ala Thr Thr Ala
27080 27085 27090
Ala Cys Thr Gly Gly Ala Ala Gly Gly Gly Gly Ala Ala Thr Ala
27095 27100 27105
Gly Gly Ala Ala Cys Gly Gly Ala Gly Gly Ala Ala Thr Thr Ala
27110 27115 27120
Ala Ala Ala Ala Ala Thr Gly Ala Cys Gly Ala Thr Gly Gly Thr
27125 27130 27135
Gly Thr Ala Ala Cys Ala Ala Ala Cys Ala Ala Ala Gly Gly Ala
27140 27145 27150
Gly Thr Cys Gly Gly Cys Thr Thr Gly Cys Gly Thr Gly Thr Ala
27155 27160 27165
Ala Gly Ala Cys Thr Thr Gly Gly Ala Gly Ala Thr Gly Ala Cys
27170 27175 27180
Gly Gly Cys Gly Gly Gly Cys Thr Gly Ala Cys Ala Thr Thr Thr
27185 27190 27195
Gly Ala Thr Ala Ala Ala Ala Ala Gly Gly Gly Thr Gly Ala Thr
27200 27205 27210
Thr Thr Ala Gly Thr Ala Gly Cys Cys Thr Gly Gly Ala Ala Thr
27215 27220 27225
Ala Ala Ala Ala Ala Ala Gly Ala Thr Gly Ala Cys Ala Gly Gly
27230 27235 27240
Cys Gly Cys Ala Cys Cys Cys Thr Gly Thr Gly Gly Ala Cys Ala
27245 27250 27255
Ala Cys Cys Cys Cys Thr Gly Ala Cys Ala Cys Ala Thr Cys Thr
27260 27265 27270
Cys Cys Ala Ala Ala Thr Thr Gly Cys Ala Ala Ala Ala Thr Gly
27275 27280 27285
Ala Gly Thr Ala Cys Ala Gly Ala Ala Ala Ala Gly Gly Ala Thr
27290 27295 27300
Thr Cys Thr Ala Ala Ala Cys Thr Thr Ala Cys Gly Thr Thr Gly
27305 27310 27315
Ala Cys Ala Cys Thr Thr Ala Cys Ala Ala Ala Gly Thr Gly Thr
27320 27325 27330
Gly Gly Ala Ala Gly Thr Cys Ala Gly Gly Thr Thr Cys Thr Gly
27335 27340 27345
Gly Gly Ala Ala Ala Thr Gly Thr Ala Thr Cys Thr Thr Thr Ala
27350 27355 27360
Cys Thr Thr Gly Cys Ala Gly Thr Thr Ala Cys Ala Gly Gly Thr
27365 27370 27375
Gly Ala Ala Thr Ala Thr Cys Ala Thr Cys Ala Ala Ala Thr Gly
27380 27385 27390
Ala Cys Thr Gly Cys Thr Ala Cys Thr Ala Cys Ala Ala Ala Gly
27395 27400 27405
Ala Ala Gly Gly Ala Thr Gly Thr Ala Ala Ala Ala Ala Thr Ala
27410 27415 27420
Thr Cys Thr Thr Thr Ala Cys Thr Ala Thr Thr Thr Gly Ala Thr
27425 27430 27435
Gly Ala Gly Ala Ala Thr Gly Gly Ala Ala Thr Thr Cys Thr Ala
27440 27445 27450
Thr Thr Ala Cys Cys Ala Thr Cys Thr Thr Cys Gly Thr Cys Cys
27455 27460 27465
Cys Thr Thr Ala Gly Cys Ala Ala Ala Gly Ala Thr Thr Ala Thr
27470 27475 27480
Thr Gly Gly Ala Ala Thr Thr Ala Cys Ala Gly Ala Ala Gly Thr
27485 27490 27495
Gly Ala Thr Gly Ala Thr Thr Cys Thr Ala Thr Thr Gly Thr Ala
27500 27505 27510
Thr Cys Thr Cys Ala Ala Ala Ala Ala Thr Ala Thr Ala Ala Thr
27515 27520 27525
Ala Ala Thr Gly Cys Ala Gly Thr Thr Cys Cys Ala Thr Thr Cys
27530 27535 27540
Ala Thr Gly Cys Cys Ala Ala Ala Cys Cys Thr Gly Ala Cys Ala
27545 27550 27555
Gly Cys Thr Thr Ala Thr Cys Cys Ala Ala Ala Ala Cys Cys Ala
27560 27565 27570
Ala Gly Cys Gly Cys Thr Cys Ala Ala Ala Ala Thr Gly Cys Ala
27575 27580 27585
Ala Ala Ala Ala Ala Cys Thr Ala Thr Thr Cys Ala Ala Gly Ala
27590 27595 27600
Ala Cys Thr Ala Ala Ala Ala Thr Cys Ala Thr Ala Ala Gly Thr
27605 27610 27615
Ala Ala Thr Gly Thr Cys Thr Ala Cys Thr Thr Ala Gly Gly Thr
27620 27625 27630
Gly Cys Thr Cys Thr Thr Ala Cys Cys Thr Ala Cys Cys Ala Ala
27635 27640 27645
Cys Cys Thr Gly Thr Ala Ala Thr Thr Ala Thr Cys Ala Cys Thr
27650 27655 27660
Ala Thr Thr Gly Cys Ala Thr Thr Thr Ala Ala Thr Cys Ala Gly
27665 27670 27675
Gly Ala Ala Ala Cys Thr Gly Ala Ala Ala Ala Thr Gly Gly Ala
27680 27685 27690
Thr Gly Thr Gly Cys Thr Thr Ala Thr Thr Cys Thr Ala Thr Ala
27695 27700 27705
Ala Cys Ala Thr Thr Thr Ala Cys Cys Thr Thr Cys Ala Cys Thr
27710 27715 27720
Thr Gly Gly Cys Ala Ala Ala Ala Ala Gly Ala Cys Thr Ala Thr
27725 27730 27735
Thr Cys Thr Gly Cys Cys Cys Ala Ala Cys Ala Gly Thr Thr Thr
27740 27745 27750
Gly Ala Thr Gly Thr Thr Ala Cys Ala Thr Cys Thr Thr Thr Thr
27755 27760 27765
Ala Cys Cys Thr Thr Cys Thr Cys Ala Thr Ala Thr Cys Thr Thr
27770 27775 27780
Ala Cys Cys Cys Ala Ala Gly Ala Gly Ala Ala Cys Ala Ala Ala
27785 27790 27795
Gly Ala Cys Ala Ala Ala Gly Ala Cys Thr Ala Ala Thr Ala Ala
27800 27805 27810
Ala Ala Thr Gly Thr Thr Thr Thr Gly Ala Ala Cys Thr Gly Ala
27815 27820 27825
Ala Thr Thr Thr Ala Thr Gly Ala Ala Thr Cys Thr Thr Thr Ala
27830 27835 27840
Thr Thr Thr Ala Thr Thr Thr Thr Thr Ala Cys Ala Cys Cys Ala
27845 27850 27855
Gly Cys Ala Cys Gly Gly Gly Thr Ala Gly Thr Cys Ala Gly Thr
27860 27865 27870
Thr Thr Cys Cys Cys Ala Cys Cys Ala Cys Cys Ala Gly Cys Cys
27875 27880 27885
Cys Ala Thr Thr Thr Cys Ala Cys Ala Gly Thr Gly Thr Ala Ala
27890 27895 27900
Ala Cys Ala Gly Thr Cys Cys Thr Thr Thr Cys Thr Cys Cys Cys
27905 27910 27915
Cys Gly Gly Cys Thr Gly Gly Cys Cys Thr Thr Ala Ala Ala Ala
27920 27925 27930
Ala Gly Cys Ala Thr Cys Ala Thr Ala Thr Cys Ala Thr Gly Gly
27935 27940 27945
Gly Thr Ala Ala Cys Ala Gly Ala Cys Ala Thr Ala Thr Thr Cys
27950 27955 27960
Thr Thr Ala Gly Gly Thr Gly Thr Thr Ala Thr Ala Thr Thr Cys
27965 27970 27975
Cys Ala Cys Ala Cys Gly Gly Thr Thr Thr Cys Cys Thr Gly Thr
27980 27985 27990
Cys Gly Ala Gly Cys Cys Ala Ala Ala Cys Gly Cys Thr Cys Ala
27995 28000 28005
Thr Cys Ala Gly Thr Gly Ala Thr Ala Thr Thr Ala Ala Thr Ala
28010 28015 28020
Ala Ala Cys Thr Cys Cys Cys Cys Gly Gly Gly Cys Ala Gly Cys
28025 28030 28035
Thr Cys Ala Cys Thr Thr Ala Ala Gly Thr Thr Cys Ala Thr Gly
28040 28045 28050
Thr Cys Gly Cys Thr Gly Thr Cys Cys Ala Gly Cys Thr Gly Cys
28055 28060 28065
Thr Gly Ala Gly Cys Cys Ala Cys Ala Gly Gly Cys Thr Gly Cys
28070 28075 28080
Thr Gly Thr Cys Cys Ala Ala Cys Thr Thr Gly Cys Gly Gly Thr
28085 28090 28095
Thr Gly Cys Thr Thr Ala Ala Cys Gly Gly Gly Cys Gly Gly Cys
28100 28105 28110
Gly Ala Ala Gly Gly Ala Gly Ala Ala Gly Thr Cys Cys Ala Cys
28115 28120 28125
Gly Cys Cys Thr Ala Cys Ala Thr Gly Gly Gly Gly Gly Thr Ala
28130 28135 28140
Gly Ala Gly Thr Cys Ala Thr Ala Ala Thr Cys Gly Thr Gly Cys
28145 28150 28155
Ala Thr Cys Ala Gly Gly Ala Thr Ala Gly Gly Gly Cys Gly Gly
28160 28165 28170
Thr Gly Gly Thr Gly Cys Thr Gly Cys Ala Gly Cys Ala Gly Cys
28175 28180 28185
Gly Cys Gly Cys Gly Ala Ala Thr Ala Ala Ala Cys Thr Gly Cys
28190 28195 28200
Thr Gly Cys Cys Gly Cys Cys Gly Cys Cys Gly Cys Thr Cys Cys
28205 28210 28215
Gly Thr Cys Cys Thr Gly Cys Ala Gly Gly Ala Ala Thr Ala Cys
28220 28225 28230
Ala Ala Cys Ala Thr Gly Gly Cys Ala Gly Thr Gly Gly Thr Cys
28235 28240 28245
Thr Cys Cys Thr Cys Ala Gly Cys Gly Ala Thr Gly Ala Thr Thr
28250 28255 28260
Cys Gly Cys Ala Cys Cys Gly Cys Cys Cys Gly Cys Ala Gly Cys
28265 28270 28275
Ala Thr Ala Ala Gly Gly Cys Gly Cys Cys Thr Thr Gly Thr Cys
28280 28285 28290
Cys Thr Cys Cys Gly Gly Gly Cys Ala Cys Ala Gly Cys Ala Gly
28295 28300 28305
Cys Gly Cys Ala Cys Cys Cys Thr Gly Ala Thr Cys Thr Cys Ala
28310 28315 28320
Cys Thr Thr Ala Ala Ala Thr Cys Ala Gly Cys Ala Cys Ala Gly
28325 28330 28335
Thr Ala Ala Cys Thr Gly Cys Ala Gly Cys Ala Cys Ala Gly Cys
28340 28345 28350
Ala Cys Cys Ala Cys Ala Ala Thr Ala Thr Thr Gly Thr Thr Cys
28355 28360 28365
Ala Ala Ala Ala Thr Cys Cys Cys Ala Cys Ala Gly Thr Gly Cys
28370 28375 28380
Ala Ala Gly Gly Cys Gly Cys Thr Gly Thr Ala Thr Cys Cys Ala
28385 28390 28395
Ala Ala Gly Cys Thr Cys Ala Thr Gly Gly Cys Gly Gly Gly Gly
28400 28405 28410
Ala Cys Cys Ala Cys Ala Gly Ala Ala Cys Cys Cys Ala Cys Gly
28415 28420 28425
Thr Gly Gly Cys Cys Ala Thr Cys Ala Thr Ala Cys Cys Ala Cys
28430 28435 28440
Ala Ala Gly Cys Gly Cys Ala Gly Gly Thr Ala Gly Ala Thr Thr
28445 28450 28455
Ala Ala Gly Thr Gly Gly Cys Gly Ala Cys Cys Cys Cys Thr Cys
28460 28465 28470
Ala Thr Ala Ala Ala Cys Ala Cys Gly Cys Thr Gly Gly Ala Cys
28475 28480 28485
Ala Thr Ala Ala Ala Cys Ala Thr Thr Ala Cys Cys Thr Cys Thr
28490 28495 28500
Thr Thr Thr Gly Gly Cys Ala Thr Gly Thr Thr Gly Thr Ala Ala
28505 28510 28515
Thr Thr Cys Ala Cys Cys Ala Cys Cys Thr Cys Cys Cys Gly Gly
28520 28525 28530
Thr Ala Cys Cys Ala Thr Ala Thr Ala Ala Ala Cys Cys Thr Cys
28535 28540 28545
Thr Gly Ala Thr Thr Ala Ala Ala Cys Ala Thr Gly Gly Cys Gly
28550 28555 28560
Cys Cys Ala Thr Cys Cys Ala Cys Cys Ala Cys Cys Ala Thr Cys
28565 28570 28575
Cys Thr Ala Ala Ala Cys Cys Ala Gly Cys Thr Gly Gly Cys Cys
28580 28585 28590
Ala Ala Ala Ala Cys Cys Thr Gly Cys Cys Cys Gly Cys Cys Gly
28595 28600 28605
Gly Cys Thr Ala Thr Ala Cys Ala Cys Thr Gly Cys Ala Gly Gly
28610 28615 28620
Gly Ala Ala Cys Cys Gly Gly Gly Ala Cys Thr Gly Gly Ala Ala
28625 28630 28635
Cys Ala Ala Thr Gly Ala Cys Ala Gly Thr Gly Gly Ala Gly Ala
28640 28645 28650
Gly Cys Cys Cys Ala Gly Gly Ala Cys Thr Cys Gly Thr Ala Ala
28655 28660 28665
Cys Cys Ala Thr Gly Gly Ala Thr Cys Ala Thr Cys Ala Thr Gly
28670 28675 28680
Cys Thr Cys Gly Thr Cys Ala Thr Gly Ala Thr Ala Thr Cys Ala
28685 28690 28695
Ala Thr Gly Thr Thr Gly Gly Cys Ala Cys Ala Ala Cys Ala Cys
28700 28705 28710
Ala Gly Gly Cys Ala Cys Ala Cys Gly Thr Gly Cys Ala Thr Ala
28715 28720 28725
Cys Ala Cys Thr Thr Cys Cys Thr Cys Ala Gly Gly Ala Thr Thr
28730 28735 28740
Ala Cys Ala Ala Gly Cys Thr Cys Cys Thr Cys Cys Cys Gly Cys
28745 28750 28755
Gly Thr Thr Ala Gly Ala Ala Cys Cys Ala Thr Ala Thr Cys Cys
28760 28765 28770
Cys Ala Gly Gly Gly Ala Ala Cys Ala Ala Cys Cys Cys Ala Thr
28775 28780 28785
Thr Cys Cys Thr Gly Ala Ala Thr Cys Ala Gly Cys Gly Thr Ala
28790 28795 28800
Ala Ala Thr Cys Cys Cys Ala Cys Ala Cys Thr Gly Cys Ala Gly
28805 28810 28815
Gly Gly Ala Ala Gly Ala Cys Cys Thr Cys Gly Cys Ala Cys Gly
28820 28825 28830
Thr Ala Ala Cys Thr Cys Ala Cys Gly Thr Thr Gly Thr Gly Cys
28835 28840 28845
Ala Thr Thr Gly Thr Cys Ala Ala Ala Gly Thr Gly Thr Thr Ala
28850 28855 28860
Cys Ala Thr Thr Cys Gly Gly Gly Cys Ala Gly Cys Ala Gly Cys
28865 28870 28875
Gly Gly Ala Thr Gly Ala Thr Cys Cys Thr Cys Cys Ala Gly Thr
28880 28885 28890
Ala Thr Gly Gly Thr Ala Gly Cys Gly Cys Gly Gly Gly Thr Thr
28895 28900 28905
Thr Cys Thr Gly Thr Cys Thr Cys Ala Ala Ala Ala Gly Gly Ala
28910 28915 28920
Gly Gly Thr Ala Gly Ala Cys Gly Ala Thr Cys Cys Cys Thr Ala
28925 28930 28935
Cys Thr Gly Thr Ala Cys Gly Gly Ala Gly Thr Gly Cys Gly Cys
28940 28945 28950
Cys Gly Ala Gly Ala Cys Ala Ala Cys Cys Gly Ala Gly Ala Thr
28955 28960 28965
Cys Gly Thr Gly Thr Thr Gly Gly Thr Cys Gly Thr Ala Gly Thr
28970 28975 28980
Gly Thr Cys Ala Thr Gly Cys Cys Ala Ala Ala Thr Gly Gly Ala
28985 28990 28995
Ala Cys Gly Cys Cys Gly Gly Ala Cys Gly Thr Ala Gly Thr Cys
29000 29005 29010
Ala Thr Thr Gly Ala Ala Ala Thr Gly Gly Ala Thr Thr Cys Thr
29015 29020 29025
Cys Thr Thr Gly Cys Gly Thr Ala Cys Cys Thr Thr Gly Thr Cys
29030 29035 29040
Gly Thr Ala Cys Thr Thr Cys Thr Gly Cys Cys Ala Gly Cys Ala
29045 29050 29055
Gly Ala Ala Ala Gly Thr Gly Gly Cys Thr Cys Gly Gly Gly Ala
29060 29065 29070
Ala Cys Ala Gly Cys Ala Gly Ala Thr Ala Cys Cys Thr Thr Thr
29075 29080 29085
Cys Cys Thr Cys Cys Thr Gly Cys Thr Gly Thr Cys Cys Thr Thr
29090 29095 29100
Cys Cys Gly Cys Thr Gly Cys Thr Gly Ala Cys Gly Cys Thr Cys
29105 29110 29115
Ala Gly Thr Cys Ala Thr Cys Cys Ala Ala Cys Thr Gly Ala Ala
29120 29125 29130
Gly Thr Ala Cys Ala Gly Cys Cys Ala Thr Thr Cys Cys Cys Gly
29135 29140 29145
Cys Ala Gly Gly Thr Thr Cys Thr Cys Cys Ala Gly Cys Ala Gly
29150 29155 29160
Cys Thr Cys Cys Thr Gly Thr Gly Cys Ala Thr Cys Thr Gly Ala
29165 29170 29175
Thr Gly Ala Ala Ala Cys Ala Ala Ala Ala Gly Thr Cys Cys Cys
29180 29185 29190
Gly Thr Cys Gly Ala Thr Gly Cys Gly Gly Ala Thr Thr Cys Cys
29195 29200 29205
Cys Cys Thr Thr Ala Ala Ala Ala Cys Ala Thr Cys Ala Gly Cys
29210 29215 29220
Cys Ala Gly Gly Ala Cys Ala Thr Thr Gly Thr Ala Gly Gly Cys
29225 29230 29235
Cys Ala Thr Cys Cys Cys Ala Ala Thr Cys Cys Ala Gly Thr Thr
29240 29245 29250
Ala Ala Thr Gly Cys Ala Thr Cys Cys Thr Gly Ala Thr Cys Thr
29255 29260 29265
Ala Thr Cys Ala Thr Gly Ala Ala Gly Ala Gly Gly Ala Gly Gly
29270 29275 29280
Thr Gly Gly Gly Gly Gly Ala Ala Gly Ala Ala Cys Thr Gly Gly
29285 29290 29295
Ala Ala Gly Ala Ala Cys Cys Ala Thr Thr Thr Thr Thr Ala Thr
29300 29305 29310
Thr Cys Cys Ala Ala Gly Cys Gly Gly Thr Cys Thr Cys Gly Ala
29315 29320 29325
Ala Gly Gly Ala Cys Gly Ala Thr Ala Ala Ala Gly Thr Gly Cys
29330 29335 29340
Ala Ala Gly Thr Cys Ala Cys Gly Cys Ala Gly Gly Thr Gly Ala
29345 29350 29355
Cys Ala Gly Cys Gly Thr Thr Cys Cys Cys Cys Gly Cys Cys Gly
29360 29365 29370
Cys Thr Gly Thr Gly Cys Thr Gly Gly Thr Gly Gly Ala Ala Ala
29375 29380 29385
Cys Ala Gly Ala Cys Ala Gly Cys Cys Ala Gly Gly Thr Cys Ala
29390 29395 29400
Ala Ala Ala Cys Cys Cys Ala Cys Thr Cys Thr Ala Thr Thr Thr
29405 29410 29415
Thr Cys Ala Ala Gly Gly Thr Gly Cys Thr Cys Gly Ala Cys Thr
29420 29425 29430
Gly Thr Gly Gly Cys Thr Thr Cys Gly Ala Gly Cys Ala Gly Thr
29435 29440 29445
Gly Gly Cys Thr Cys Thr Ala Cys Gly Cys Gly Thr Ala Cys Ala
29450 29455 29460
Thr Cys Cys Ala Gly Cys Ala Thr Ala Ala Gly Ala Ala Thr Cys
29465 29470 29475
Ala Cys Ala Thr Thr Ala Ala Ala Gly Gly Cys Thr Gly Gly Ala
29480 29485 29490
Cys Cys Thr Cys Cys Ala Thr Cys Gly Ala Thr Thr Thr Cys Ala
29495 29500 29505
Thr Cys Ala Ala Thr Cys Ala Thr Cys Ala Gly Gly Thr Thr Ala
29510 29515 29520
Cys Ala Cys Thr Cys Ala Thr Thr Cys Ala Cys Cys Ala Thr Cys
29525 29530 29535
Cys Cys Cys Ala Gly Gly Thr Ala Ala Thr Thr Cys Thr Cys Ala
29540 29545 29550
Thr Thr Thr Thr Thr Cys Cys Ala Gly Cys Cys Thr Thr Gly Gly
29555 29560 29565
Ala Thr Thr Ala Thr Thr Thr Cys Thr Ala Cys Ala Ala Ala Thr
29570 29575 29580
Thr Gly Thr Thr Gly Gly Thr Gly Thr Ala Ala Gly Thr Cys Cys
29585 29590 29595
Ala Cys Thr Cys Cys Gly Cys Ala Cys Ala Thr Gly Thr Gly Gly
29600 29605 29610
Ala Ala Ala Ala Gly Thr Thr Cys Cys Cys Ala Cys Ala Gly Cys
29615 29620 29625
Gly Cys Cys Cys Cys Cys Thr Cys Cys Ala Cys Thr Thr Thr Cys
29630 29635 29640
Ala Thr Ala Ala Thr Cys Ala Gly Gly Cys Ala Gly Ala Cys Cys
29645 29650 29655
Thr Thr Cys Ala Thr Ala Thr Thr Ala Gly Ala Ala Ala Cys Ala
29660 29665 29670
Gly Ala Thr Cys Cys Thr Gly Cys Thr Gly Cys Thr Cys Cys Ala
29675 29680 29685
Cys Cys Ala Cys Cys Thr Gly Cys Ala Gly Cys Gly Thr Gly Thr
29690 29695 29700
Thr Cys Ala Ala Ala Ala Cys Ala Ala Cys Ala Ala Gly Ala Thr
29705 29710 29715
Thr Cys Ala Ala Thr Gly Ala Gly Gly Thr Thr Cys Thr Gly Cys
29720 29725 29730
Cys Cys Thr Cys Thr Gly Cys Cys Cys Thr Cys Ala Gly Cys Thr
29735 29740 29745
Cys Ala Cys Gly Thr Cys Thr Cys Ala Gly Cys Gly Thr Cys Ala
29750 29755 29760
Gly Cys Thr Gly Cys Ala Ala Ala Ala Ala Gly Thr Cys Ala Cys
29765 29770 29775
Thr Cys Ala Ala Gly Thr Cys Cys Thr Cys Ala Gly Cys Cys Ala
29780 29785 29790
Cys Thr Ala Cys Ala Gly Cys Thr Gly Ala Cys Ala Ala Thr Thr
29795 29800 29805
Cys Ala Gly Ala Gly Cys Cys Ala Gly Gly Gly Cys Thr Ala Ala
29810 29815 29820
Gly Cys Gly Thr Gly Gly Gly Ala Cys Thr Gly Gly Cys Ala Ala
29825 29830 29835
Gly Cys Gly Thr Gly Ala Gly Thr Gly Ala Gly Thr Ala Cys Thr
29840 29845 29850
Thr Thr Ala Ala Thr Gly Cys Thr Cys Cys Ala Ala Ala Gly Cys
29855 29860 29865
Thr Ala Gly Cys Ala Cys Cys Cys Ala Ala Ala Ala Ala Cys Thr
29870 29875 29880
Gly Cys Ala Thr Gly Cys Thr Gly Gly Ala Ala Thr Ala Ala Gly
29885 29890 29895
Cys Thr Cys Thr Cys Thr Thr Thr Gly Thr Gly Thr Cys Ala Cys
29900 29905 29910
Cys Gly Gly Thr Gly Ala Thr Gly Cys Cys Thr Thr Cys Cys Ala
29915 29920 29925
Ala Thr Ala Gly Gly Thr Gly Ala Gly Thr Gly Ala Thr Ala Ala
29930 29935 29940
Ala Gly Cys Gly Ala Gly Gly Thr Ala Gly Thr Thr Thr Thr Thr
29945 29950 29955
Cys Thr Thr Thr Ala Ala Thr Cys Ala Thr Thr Thr Gly Ala Gly
29960 29965 29970
Thr Ala Ala Thr Ala Gly Ala Ala Ala Ala Gly Thr Cys Cys Thr
29975 29980 29985
Cys Thr Ala Ala Ala Thr Ala Ala Gly Thr Cys Ala Cys Thr Ala
29990 29995 30000
Gly Gly Ala Cys Cys Cys Cys Ala Gly Gly Ala Ala Cys Cys Ala
30005 30010 30015
Cys Ala Ala Thr Gly Thr Gly Gly Thr Ala Gly Cys Thr Gly Ala
30020 30025 30030
Cys Ala Gly Cys Gly Thr Gly Thr Cys Gly Cys Thr Cys Ala Ala
30035 30040 30045
Gly Cys Ala Thr Gly Gly Thr Thr Ala Gly Thr Ala Gly Ala Gly
30050 30055 30060
Ala Thr Gly Ala Gly Ala Gly Thr Cys Thr Gly Ala Ala Ala Ala
30065 30070 30075
Ala Cys Ala Gly Ala Ala Ala Gly Cys Ala Thr Gly Cys Ala Cys
30080 30085 30090
Thr Ala Ala Ala Cys Cys Ala Gly Ala Gly Thr Thr Gly Cys Cys
30095 30100 30105
Ala Gly Thr Cys Thr Cys Ala Cys Thr Gly Ala Ala Gly Gly Ala
30110 30115 30120
Ala Ala Ala Ala Thr Cys Ala Cys Thr Cys Thr Cys Thr Cys Cys
30125 30130 30135
Ala Gly Cys Ala Gly Cys Ala Ala Ala Gly Thr Gly Cys Cys Cys
30140 30145 30150
Ala Cys Thr Gly Gly Gly Thr Gly Gly Cys Cys Cys Thr Cys Thr
30155 30160 30165
Cys Gly Gly Ala Cys Ala Thr Ala Cys Ala Ala Ala Ala Ala Thr
30170 30175 30180
Cys Gly Ala Thr Cys Cys Gly Thr Gly Thr Gly Gly Thr Thr Ala
30185 30190 30195
Ala Ala Gly Ala Gly Cys Ala Gly Cys Ala Cys Ala Gly Thr Thr
30200 30205 30210
Ala Gly Cys Thr Cys Cys Thr Gly Thr Cys Thr Thr Cys Thr Cys
30215 30220 30225
Cys Cys Ala Gly Cys Ala Ala Ala Gly Ala Thr Cys Ala Cys Ala
30230 30235 30240
Thr Cys Gly Gly Ala Cys Thr Gly Gly Gly Thr Thr Ala Gly Thr
30245 30250 30255
Ala Thr Gly Cys Cys Cys Cys Thr Gly Gly Ala Ala Thr Gly Gly
30260 30265 30270
Thr Ala Gly Thr Cys Ala Thr Thr Cys Ala Ala Gly Gly Cys Cys
30275 30280 30285
Ala Thr Ala Ala Ala Thr Cys Thr Gly Cys Cys Thr Thr Gly Gly
30290 30295 30300
Thr Ala Gly Cys Cys Ala Thr Thr Ala Gly Gly Ala Ala Thr Cys
30305 30310 30315
Ala Gly Cys Ala Cys Gly Cys Thr Cys Ala Cys Thr Cys Thr Cys
30320 30325 30330
Ala Ala Gly Thr Gly Ala Ala Cys Cys Ala Ala Ala Ala Cys Cys
30335 30340 30345
Ala Cys Cys Cys Cys Ala Thr Gly Cys Gly Gly Ala Gly Gly Ala
30350 30355 30360
Ala Thr Gly Thr Gly Gly Ala Ala Ala Gly Ala Thr Thr Cys Thr
30365 30370 30375
Gly Gly Gly Cys Ala Ala Ala Ala Ala Ala Ala Gly Gly Thr Ala
30380 30385 30390
Thr Ala Thr Cys Thr Ala Thr Thr Gly Cys Thr Ala Gly Thr Cys
30395 30400 30405
Cys Cys Thr Thr Cys Cys Thr Gly Gly Ala Cys Gly Gly Gly Ala
30410 30415 30420
Gly Cys Ala Ala Thr Cys Cys Cys Thr Cys Cys Ala Gly Gly Gly
30425 30430 30435
Cys Thr Ala Thr Cys Thr Ala Thr Gly Ala Ala Ala Gly Cys Ala
30440 30445 30450
Thr Ala Cys Ala Gly Ala Gly Ala Thr Thr Cys Ala Gly Cys Cys
30455 30460 30465
Ala Thr Ala Gly Cys Thr Cys Ala Gly Cys Cys Cys Gly Cys Thr
30470 30475 30480
Thr Ala Cys Cys Ala Gly Thr Ala Gly Ala Cys Ala Gly Ala Gly
30485 30490 30495
Ala Gly Cys Ala Cys Ala Gly Cys Ala Gly Thr Ala Cys Ala Ala
30500 30505 30510
Gly Cys Gly Cys Cys Ala Ala Cys Ala Gly Cys Ala Gly Cys Gly
30515 30520 30525
Ala Cys Thr Gly Ala Cys Thr Ala Cys Cys Cys Ala Cys Thr Gly
30530 30535 30540
Ala Cys Cys Cys Ala Gly Cys Thr Cys Cys Cys Thr Ala Thr Thr
30545 30550 30555
Thr Ala Ala Ala Gly Gly Cys Ala Cys Cys Thr Thr Ala Cys Ala
30560 30565 30570
Cys Thr Gly Ala Cys Gly Thr Ala Ala Thr Gly Ala Cys Cys Ala
30575 30580 30585
Ala Ala Gly Gly Thr Cys Thr Ala Ala Ala Ala Ala Cys Cys Cys
30590 30595 30600
Cys Gly Cys Cys Ala Ala Ala Ala Ala Ala Ala Cys Ala Cys Ala
30605 30610 30615
Cys Ala Cys Gly Cys Cys Cys Thr Gly Gly Gly Thr Gly Thr Thr
30620 30625 30630
Thr Thr Thr Cys Gly Cys Gly Ala Ala Ala Ala Cys Ala Cys Thr
30635 30640 30645
Thr Cys Cys Gly Cys Gly Thr Thr Cys Thr Cys Ala Cys Thr Thr
30650 30655 30660
Cys Cys Thr Cys Gly Thr Ala Thr Cys Gly Ala Thr Thr Thr Cys
30665 30670 30675
Gly Thr Gly Ala Cys Thr Cys Ala Ala Cys Thr Thr Cys Cys Gly
30680 30685 30690
Gly Gly Thr Thr Cys Cys Cys Ala Cys Gly Thr Thr Ala Cys Gly
30695 30700 30705
Thr Cys Ala Cys Thr Thr Cys Thr Gly Cys Cys Cys Thr Thr Ala
30710 30715 30720
Cys Ala Thr Gly Thr Ala Ala Cys Thr Cys Ala Gly Cys Cys Gly
30725 30730 30735
Thr Ala Gly Gly Gly Cys Gly Cys Cys Ala Thr Cys Thr Thr Gly
30740 30745 30750
Cys Cys Cys Ala Cys Gly Thr Cys Cys Ala Ala Ala Ala Thr Gly
30755 30760 30765
Gly Cys Thr Thr Cys Cys Ala Thr Gly Thr Cys Cys Gly Gly Cys
30770 30775 30780
Cys Ala Cys Gly Cys Cys Thr Cys Cys Gly Cys Gly Gly Cys Gly
30785 30790 30795
Ala Cys Cys Gly Thr Thr Ala Gly Cys Cys Gly Thr Gly Cys Gly
30800 30805 30810
Thr Cys Gly Thr Gly Ala Cys Gly Thr Cys Ala Thr Thr Thr Gly
30815 30820 30825
Cys Ala Thr Cys Ala Cys Cys Gly Thr Thr Thr Cys Thr Cys Gly
30830 30835 30840
Thr Cys Cys Ala Ala Thr Cys Ala Gly Cys Gly Thr Thr Gly Gly
30845 30850 30855
Cys Thr Cys Cys Gly Cys Cys Cys Cys Ala Ala Ala Ala Cys Cys
30860 30865 30870
Gly Thr Thr Ala Ala Ala Ala Thr Thr Cys Ala Ala Ala Ala Gly
30875 30880 30885
Cys Thr Cys Ala Thr Thr Thr Gly Cys Ala Thr Ala Thr Thr Ala
30890 30895 30900
Ala Cys Thr Thr Thr Thr Gly Thr Thr Thr Ala Cys Thr Thr Thr
30905 30910 30915
Gly Thr Gly Gly Gly Gly Thr Ala Thr Ala Thr Thr Ala Thr Thr
30920 30925 30930
Gly Ala Thr Gly Ala Thr Gly
30935 30940
<210> 9
<211> 30982
<212> DNA
<213> 人工序列
<220>
<223> Ad26.HVRPtr13.FLuc
<400> 9
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat tccagccagt gggagcaagc aaaaccaggc aatgggggaa 18000
ctatggaaac acacacatat ggtgtggccc caatgggcgg agagaatatt acaaaagatg 18060
gtcttcaaat tggaactgat gctacagcgg atcagaataa accaatttat gctgacaaaa 18120
ctttccagcc agaacctcaa gtaggagaag aaaattggca agaaactgaa agcttttatg 18180
gtggtagggc tcttaaaaaa gacactaaaa tgaaaccatg ctatggatct tttgctagac 18240
ctactaatga gaaaggaggt caggcaaagt tcaaaccagt taatgaagga gaacaaccta 18300
aagatctgga tatagatctg gctttctttg atactcccgg tggcactgtg aatggccaag 18360
atgagtataa agcagacatt gtcatgtaca ctgaaaatgt taatcttgaa acaccagaca 18420
ctcatgtggt ttacaagcca ggcaaggaag atgcaagttc tgaaattaac ctggttcagc 18480
agtccatgcc aaacagaccc aactacattg gctttaggga caactttgta ggtctcatgt 18540
attacaacag caccggaaat atgggtgtgc tggctggtca ggcttctcag ttgaacgctg 18600
tggtcgactt gcaagacaga aacaccgagt tatcttacca gctattgcta gattctctgg 18660
gtgacagaac cagatacttt agcatgtgga actctgcggt ggacagttac gatccagatg 18720
tcaggatcat tgaaaatcac ggtgtggaag atgaacttcc aaactattgc ttcccattgg 18780
atggatctgg cactaacgcc gcctatcaag gtgtaaaagt aaaaaatggt gaagatggtg 18840
atcttgagag cgagtgggaa aatgatgata ctgtggcagc tcgaaatcaa atatgcaaag 18900
gcaatatttt cgccatggag atcaacctgc aggccaacct gtggaagagt tttctgtact 18960
cgaacgtggc cctgtacctg cccgactcct acaagtacac gccggccaac gtcaagctgc 19020
ccgccaacac caacacctac gagtacatga acggccgcgt ggtagccccc tcgctggtgg 19080
acgcctacat caacatcggc gcccgctggt cgttggatcc catggacaac gtcaacccct 19140
tcaaccacca ccgcaatgcg ggcctgcgct accgctccat gctgctgggc aacggccgct 19200
acgtgccctt ccacatccaa gtgccccaaa agttctttgc catcaagaac ctgctcctgc 19260
tcccgggctc ctacacctac gagtggaact tccgcaagga cgtcaacatg atcctgcaga 19320
gttccctcgg caacgacctg cgcgtcgacg gcgcctccgt ccgcttcgac agcgtcaacc 19380
tatacgccac tttcttcccc atggcgcaca acaccgcttc aaccttggaa gccatgctgc 19440
gcaacgacac caacgaccag tccttcaacg actacctctc ggccgccaac atgctctacc 19500
ccatcccggc caaggccacc aacgtgccca tctccatccc atcgcgcaac tgggccgcct 19560
tccgcggctg gagtttcacc cggctcaaga ccaaggaaac tccttccctc ggctcgggtt 19620
tcgaccccta ctttgtctac tcgggctcca tcccctacct cgacgggacc ttctacctca 19680
accacacctt caagaaggtc tccatcatgt tcgactcctc ggtcagctgg cccggcaacg 19740
accggctgct cacgccgaac gagttcgaga tcaagcgcag cgtcgacggg gagggctaca 19800
acgtggccca atgcaacatg accaaggact ggttcctcgt ccagatgctc tcccactaca 19860
acatcggcta ccagggcttc cacgtgcccg agggctacaa ggaccgcatg tactccttct 19920
tccgcaactt ccagcccatg agcaggcagg tggtcgatga gatcaactac aaggactaca 19980
aggccgtcac cctgcccttc cagcacaata actcgggctt caccggctac ctcgcaccca 20040
ccatgcgcca ggggcagccc taccccgcca acttccccta cccgctcatc ggtcagacag 20100
ccgtgccctc cgtcacccag aaaaagttcc tctgcgacag ggtcatgtgg cgcatcccct 20160
tctccagcaa cttcatgtcc atgggcgccc tcaccgacct gggtcagaac atgctctacg 20220
ccaactcggc ccacgcgctc gacatgacct tcgaggtgga ccccatggat gagcccaccc 20280
tcctctatct tctcttcgaa gttttcgacg tggtcagagt acaccagccg caccgcggcg 20340
tcatcgaggc cgtctacctg cgcacgccct tctccgccgg caacgccacc acctaagcat 20400
gagcggctcc agcgaacgag agctcgcggc catcgtgcgc gacctgggct gcgggcccta 20460
ctttttgggc acccacgaca agcgcttccc gggctttctc gccggcgaca agctggcctg 20520
cgccatcgtc aacacggccg gccgcgagac cggaggcgtg cactggctcg ccttcggctg 20580
gaacccgcgc tcgcgcacct gctacatgtt cgaccccttt gggttctcgg accgccggct 20640
caagcagatt tacagcttcg agtacgaggc catgctgcgc cgcagcgccc tggcctcctc 20700
gcccgaccgc tgtctcagcc tcgagcagtc cactcagacc gtgcaggggc ccgactccgc 20760
cgcctgcgga ctcttctgtt gcatgttctt gcatgccttc gtgcactggc ccgaccgacc 20820
catggacgga aaccccacca tgaacttgct gacgggggtg cccaacggca tgctacaatc 20880
gccacaggtg ctgcccaccc tcaggcgcaa ccaggaggaa ctctaccgct tcctcgcgcg 20940
ccactcccct tactttcgct cccaccgcgc cgccatcgaa cacgccaccg cttttgacaa 21000
aatgaaacaa ctgcgtgtat ctcaataaac agcactttta ttttacatgc actggagtat 21060
atgcaagtta tttaaaagtc gaaggggttc tcgcgctcgt cgttgtgcgc cgcgctgggg 21120
agggccacgt tgcggtactg gtacttgggc tgccacttga actcggggat caccagtttg 21180
ggcactgggg tctcggggaa ggtctcgctc cacatgcgcc ggctcatctg cagggcgccc 21240
agcatgtccg gggcggagat cttgaaatcg cagttggggc cggtgctctg cgcgcgcgag 21300
ttgcggtaca cggggttgca gcactggaac accatcagac tggggtactt cacactagcc 21360
agcacgctct tgtcgctgat ctgatccttg tccagatcct cggcgttgct caggccgaac 21420
ggggtcatct tgcacagctg gcgtcccagg aagggcacgc tctgaggctt gtggttacac 21480
tcgcagtgca cgggcatcag catcatcccc gcgccgcgct gcatattcgg gtagagggcc 21540
ttgacaaagg ccgcgatctg cttgaaagct tgctgggcct tggccccctc gctgaaaaac 21600
aggccgcagc tcttcccgct gaactggtta ttcccacacc cggcatcctg cacgcagcag 21660
cgcgcgtcat ggctggtcag ttgcaccacg ctccgtcccc agcggttctg ggtcacctta 21720
gccttgctgg gctgctcctt caacgcgcgc tgcccgttct cgctggtcac atccatctcc 21780
accacgtggt ccttgtggat catcatcgtc ccgtgcagac acttgagctg gccttccacc 21840
tcggtgcagc cgtgatccca cagggcgcaa ccggtgcact cccagttctt gtgcgcaatc 21900
ccgctgtggc tgaagatgta accttgcaac atgcggccca tgatggtgct aaatgctttc 21960
tgggtggtga aggtcagttg catcccgcgg gcctcctcgt tcatccaggt ctggcacatc 22020
ttctggaaga tctcggtctg ctcgggcatg agcttgtaag catcgcgcag gccgctgtcg 22080
acgcggtagc gttccatcag cacgttcatg gtatccatgc ccttctccca ggacgagacc 22140
agaggcagac tcagagggtt gcgtacgttc aggacaccgg gggtcgcggg ctcgacgatg 22200
cgttttccgt ccttgccttc cttcaataga accggcggct ggctgaatcc cactcccacg 22260
atcacggcat cttcctgggg catctcttcg tcggggtcta ccttggtcac atgcttggtc 22320
tttctggctt gcttcttttt tggagggctg tccacgggga gcacgtcctc ctcggaagac 22380
ccggagccca cccgctgata ctttcggcgc ttggtgggca gaggaggtgg cggcgagggg 22440
ctcctctcct gctccggcgg atagcgcgcc gacccgtggc cccggggcgg agtggcctct 22500
cggcccatga accggcgcac gtcctgactg ccgccggcca ttgtttccta ggggaagatg 22560
gaggagcagc cgcgtaagca ggagcaggag gaggacttaa ccacccacga gcaacccaaa 22620
atcgagcagg acctgggctt cgaagagccg gctcgtctag aacccccaca ggatgaacag 22680
gagcacgagc aagacgcagg ccaggaggag accgacgctg ggctcgagca tggctacctg 22740
ggaggagagg aggatgtgct gctgaaacac ctgcagcgcc agtccctcat cctccgggac 22800
gccctggccg accggagcga aacccccctc agcgtcgagg agctgtgtcg ggcctacgag 22860
ctcaacctct tctcgccgcg cgtacccccc aaacgccagc ccaacggcac ctgcgagccc 22920
aacccgcgtc tcaacttcta tcccgtcttt gcggtccccg aagccctcgc cacctatcac 22980
atctttttca agaaccaaaa gatccccgtc tcctgccgcg ccaaccgcac cagcgccgac 23040
gcgctcctcg ctttggggcc cggcgcgcgc atacctgata tcgcttccct ggaagaggtg 23100
cccaagatct tcgaagggct cggtcgggac gagacgcgcg cggcgaacgc tctgaaagaa 23160
acagcagagg aagagggtca cactagcgcc ctggtagagt tggaaggcga caacgccagg 23220
ctggccgtgc tcaagcgcag cgtcgagctt acccacttcg cctaccccgc cgtcaacctc 23280
ccgcccaagg tcatgcgtcg catcatggat cagctcatca tgccccacat cgaggccctc 23340
gatgaaagtc aggagcagcg ccccgaggac gcccggcccg tggtcagcga cgagatgctc 23400
gcgcgctggc tcgggacccg cgacccccag gctttggaac agcggcgcaa actcatgctg 23460
gccgtggtcc tggtcaccct tgagctcgaa tgcatgcgcc gctttttcag cgaccccgag 23520
accctgcgca aggtcgagga gaccctgcac tacactttca ggcacggttt cgtcaggcag 23580
gcctgcaaga tctccaacgt ggagctgacc aacctggtct cctgcctggg gatcctgcac 23640
gagaaccgcc tgggccagac cgtgctccac tctaccctga agggcgaggc gcggcgggac 23700
tatgtccgcg actgcgtctt tctctttctc tgccacacat ggcaagcggc catgggcgtg 23760
tggcagcagt gtctcgagga cgagaaccta aaggagctgg acaagcttct tgctagaaac 23820
cttaaaaagc tgtggacggg cttcgacgag cgcaccgtcg cctcggacct ggccgagatc 23880
gtcttccccg agcgcctgag acagacgctg aaaggcgggc tgcccgactt catgagccag 23940
agcatgttgc aaaactaccg cactttcatt cttgagcgat caggcatcct gcccgccacc 24000
tgcaacgcct tcccctccga ctttgtaccg ctgagctacc gcgagtgtcc cccgccgctg 24060
tggagccact gctacctctt gcagctggcc aactacatcg cctaccactc ggacgtgatc 24120
gaggacgtga gcggcgaggg gctgctcgag tgccactgtc gctgcaacct gtgctccccg 24180
catcgctccc tggtctgcaa cccccagctc ctgagcgaga cccaggtcat cggtaccttc 24240
gagctgcaag gtccgcagga gtccaccgct ccgctgaaac tcacgccggg gttgtggact 24300
tccgcgtacc tgcgcaaatt tgtacccgaa gactaccacg cccatgagat aaagttcttt 24360
gaggaccaat cgcgtccgca gcacgcggat ctcacggcct gcgtcatcac ccagggcgcg 24420
atcctcgccc aattgcacgc catccaaaaa tcccgccaag agtttcttct gaaaaagggt 24480
agaggggtct acctggaccc ccagacgggc gaggtgctca acccgggtct cccccagcat 24540
gccgaggaag aagcaggagc cgctagtgga ggagatggaa gaagaatggg acagccaggc 24600
agaggaggac gaatgggagg aggagacaga ggaggaagaa ttggaagagg tggaagagga 24660
gcaggcaaca gagcagcccg tcgccgcacc atccgcgccg gcagccccgc cggtcacgga 24720
tacaacctcc gctccggtca agcctcctcg tagatgggat caagtgaagg gtgacggtaa 24780
gcacgagcgg cagggctacc gatcatggag ggcccacaaa gccgcgatca tcgcctgctt 24840
gcaagactgc ggggggaaca tcgctttcgc ccgccgctac ctgctcttcc accgcggggt 24900
gaacatcccc cgcaacgtgt tgcattacta ccgtcacctt cacagctaag aaaaagcaag 24960
tcaaaggagt cgccggagga ggaggaggag gcctgaggat cgcggcgaac gagcccttga 25020
ccaccaggga gctgaggaac cggatcttcc ccactcttta tgccattttt cagcagagtc 25080
gaggtcagca gcaagagctc aaagtaaaaa accggtctct gcgctcgctc acccgcagtt 25140
gcttgtacca caaaaacgaa gatcagctgc agcgcactct cgaagacgcc gaggctctgt 25200
tccacaagta ctgcgcgctc actcttaaag actaaggcgc gcccacccgg aaaaaaggcg 25260
ggaattacct catcgccacc atgagcaagg agattcccac cccttacatg tggagctatc 25320
agccccaaat gggcctggcc gcgggcgcct cccaggacta ctccacccgc atgaactggc 25380
tcagtgccgg cccctcgatg atctcacggg tcaacggggt ccgcagtcat cgaaaccaga 25440
tattgttgga gcaggcggcg gtcacctcca cgcccagggc aaagctcaac ccgcgtaatt 25500
ggccctccac cctggtgtat caggaaatcc ccgggccgac taccgtacta cttccgcgtg 25560
acgcactggc cgaagtccgc atgactaact caggtgtcca gctggccggc ggcgcttccc 25620
ggtgcccgct ccgcccacaa tcgggtataa aaaccctggt gatccgaggc agaggcacac 25680
agctcaacga cgagttggtg agctcttcga tcggtctgcg accggacgga gtgttccaac 25740
tagccggagc cgggagatcc tccttcactc ccaaccaggc ctacctgacc ttgcagagca 25800
gctcttcgga gcctcgctcc ggaggcatcg gaaccctcca gtttgtggag gagtttgtgc 25860
cctcggtcta cttcaacccc ttctcgggat cgccaggcct ctacccggac gagttcatac 25920
cgaacttcga cgcagtgaga gaagcggtgg acggctacga ctgaatgtcc catggtgact 25980
cggctgagct cgctcggttg aggcatctgg accactgccg ccgcctgcgc tgcttcgccc 26040
gggagagctg cggactcatc tactttgagt ttcccgagga gcaccccaac ggccctgcac 26100
acggagtgcg gatcaccgta gagggcacca ccgagtctca cctggtcagg ttcttcaccc 26160
agcaaccctt cctggtcgag cgggaccggg gcgccaccac ctacaccgtc tactgcatct 26220
gtccaacccc gaagttgcat gagaattttt gttgtactct ttgtggtgag tttaataaaa 26280
gctaaactct tgcaatactc tggaccttgt cgtcgtcaac tcaacgagac cgtctacctc 26340
accaaccaga ctgaggtaaa actcacctgc agaccacaca agacctatat catctggttc 26400
ttcgagaaca cctcatttgc agtctccaac actcactgca ctagtccatg aactgatgtt 26460
gattaaaagc ccaaaaacca atcagcccct tcccccattt ccccatcccc caattactca 26520
taaaaaataa atcattggaa ttaatcattc aataaagatc acttacttga aatctgaaag 26580
tatgtctctg gtgtagttgt tcagcagcac ctcggtaccc tcctcccagc tctggtactc 26640
cagtccccgg cgggcggcga acttcctcca caccttgaaa gggatgtcaa attcctggtc 26700
cacaattttc attgtcttcc ctctcagatg gcaaagaggc tccgggtgga agatgacttc 26760
aaccccgtct acccctatgg ctacgcgcgg aatcagaata tccccttcct cactcccccc 26820
tttgtctcct ccgatggatt caaaaacttc ccccctgggg tcctgtcact taaactggct 26880
gatccaatca ccatcaacaa tggggatgtc tcacttaagg tgggaggggg acttgctgta 26940
gagcaacaga ctggtaacct aagcgtaaac cctgatgcac ccttgcaagt tgcaagtgat 27000
aagctacagc ttgctctggc tcctccattc gaggtcagag atggaaagct tgctttaaag 27060
gcaggtaatg gattaaaagt actagataat tccattactg gattgactgg attattgaat 27120
acacttgtgg tattaactgg aaggggaata ggaacggagg aattaaaaaa tgacgatggt 27180
gtaacaaaca aaggagtcgg cttgcgtgta agacttggag atgacggcgg gctgacattt 27240
gataaaaagg gtgatttagt agcctggaat aaaaaagatg acaggcgcac cctgtggaca 27300
acccctgaca catctccaaa ttgcaaaatg agtacagaaa aggattctaa acttacgttg 27360
acacttacaa agtgtggaag tcaggttctg ggaaatgtat ctttacttgc agttacaggt 27420
gaatatcatc aaatgactgc tactacaaag aaggatgtaa aaatatcttt actatttgat 27480
gagaatggaa ttctattacc atcttcgtcc cttagcaaag attattggaa ttacagaagt 27540
gatgattcta ttgtatctca aaaatataat aatgcagttc cattcatgcc aaacctgaca 27600
gcttatccaa aaccaagcgc tcaaaatgca aaaaactatt caagaactaa aatcataagt 27660
aatgtctact taggtgctct tacctaccaa cctgtaatta tcactattgc atttaatcag 27720
gaaactgaaa atggatgtgc ttattctata acatttacct tcacttggca aaaagactat 27780
tctgcccaac agtttgatgt tacatctttt accttctcat atcttaccca agagaacaaa 27840
gacaaagact aataaaatgt tttgaactga atttatgaat ctttatttat ttttacacca 27900
gcacgggtag tcagtttccc accaccagcc catttcacag tgtaaacagt cctttctccc 27960
cggctggcct taaaaagcat catatcatgg gtaacagaca tattcttagg tgttatattc 28020
cacacggttt cctgtcgagc caaacgctca tcagtgatat taataaactc cccgggcagc 28080
tcacttaagt tcatgtcgct gtccagctgc tgagccacag gctgctgtcc aacttgcggt 28140
tgcttaacgg gcggcgaagg agaagtccac gcctacatgg gggtagagtc ataatcgtgc 28200
atcaggatag ggcggtggtg ctgcagcagc gcgcgaataa actgctgccg ccgccgctcc 28260
gtcctgcagg aatacaacat ggcagtggtc tcctcagcga tgattcgcac cgcccgcagc 28320
ataaggcgcc ttgtcctccg ggcacagcag cgcaccctga tctcacttaa atcagcacag 28380
taactgcagc acagcaccac aatattgttc aaaatcccac agtgcaaggc gctgtatcca 28440
aagctcatgg cggggaccac agaacccacg tggccatcat accacaagcg caggtagatt 28500
aagtggcgac ccctcataaa cacgctggac ataaacatta cctcttttgg catgttgtaa 28560
ttcaccacct cccggtacca tataaacctc tgattaaaca tggcgccatc caccaccatc 28620
ctaaaccagc tggccaaaac ctgcccgccg gctatacact gcagggaacc gggactggaa 28680
caatgacagt ggagagccca ggactcgtaa ccatggatca tcatgctcgt catgatatca 28740
atgttggcac aacacaggca cacgtgcata cacttcctca ggattacaag ctcctcccgc 28800
gttagaacca tatcccaggg aacaacccat tcctgaatca gcgtaaatcc cacactgcag 28860
ggaagacctc gcacgtaact cacgttgtgc attgtcaaag tgttacattc gggcagcagc 28920
ggatgatcct ccagtatggt agcgcgggtt tctgtctcaa aaggaggtag acgatcccta 28980
ctgtacggag tgcgccgaga caaccgagat cgtgttggtc gtagtgtcat gccaaatgga 29040
acgccggacg tagtcattga aatggattct cttgcgtacc ttgtcgtact tctgccagca 29100
gaaagtggct cgggaacagc agataccttt cctcctgctg tccttccgct gctgacgctc 29160
agtcatccaa ctgaagtaca gccattcccg caggttctcc agcagctcct gtgcatctga 29220
tgaaacaaaa gtcccgtcga tgcggattcc ccttaaaaca tcagccagga cattgtaggc 29280
catcccaatc cagttaatgc atcctgatct atcatgaaga ggaggtgggg gaagaactgg 29340
aagaaccatt tttattccaa gcggtctcga aggacgataa agtgcaagtc acgcaggtga 29400
cagcgttccc cgccgctgtg ctggtggaaa cagacagcca ggtcaaaacc cactctattt 29460
tcaaggtgct cgactgtggc ttcgagcagt ggctctacgc gtacatccag cataagaatc 29520
acattaaagg ctggacctcc atcgatttca tcaatcatca ggttacactc attcaccatc 29580
cccaggtaat tctcattttt ccagccttgg attatttcta caaattgttg gtgtaagtcc 29640
actccgcaca tgtggaaaag ttcccacagc gccccctcca ctttcataat caggcagacc 29700
ttcatattag aaacagatcc tgctgctcca ccacctgcag cgtgttcaaa acaacaagat 29760
tcaatgaggt tctgccctct gccctcagct cacgtctcag cgtcagctgc aaaaagtcac 29820
tcaagtcctc agccactaca gctgacaatt cagagccagg gctaagcgtg ggactggcaa 29880
gcgtgagtga gtactttaat gctccaaagc tagcacccaa aaactgcatg ctggaataag 29940
ctctctttgt gtcaccggtg atgccttcca ataggtgagt gataaagcga ggtagttttt 30000
ctttaatcat ttgagtaata gaaaagtcct ctaaataagt cactaggacc ccaggaacca 30060
caatgtggta gctgacagcg tgtcgctcaa gcatggttag tagagatgag agtctgaaaa 30120
acagaaagca tgcactaaac cagagttgcc agtctcactg aaggaaaaat cactctctcc 30180
agcagcaaag tgcccactgg gtggccctct cggacataca aaaatcgatc cgtgtggtta 30240
aagagcagca cagttagctc ctgtcttctc ccagcaaaga tcacatcgga ctgggttagt 30300
atgcccctgg aatggtagtc attcaaggcc ataaatctgc cttggtagcc attaggaatc 30360
agcacgctca ctctcaagtg aaccaaaacc accccatgcg gaggaatgtg gaaagattct 30420
gggcaaaaaa aggtatatct attgctagtc ccttcctgga cgggagcaat ccctccaggg 30480
ctatctatga aagcatacag agattcagcc atagctcagc ccgcttacca gtagacagag 30540
agcacagcag tacaagcgcc aacagcagcg actgactacc cactgaccca gctccctatt 30600
taaaggcacc ttacactgac gtaatgacca aaggtctaaa aaccccgcca aaaaaacaca 30660
cacgccctgg gtgtttttcg cgaaaacact tccgcgttct cacttcctcg tatcgatttc 30720
gtgactcaac ttccgggttc ccacgttacg tcacttctgc ccttacatgt aactcagccg 30780
tagggcgcca tcttgcccac gtccaaaatg gcttccatgt ccggccacgc ctccgcggcg 30840
accgttagcc gtgcgtcgtg acgtcatttg catcaccgtt tctcgtccaa tcagcgttgg 30900
ctccgcccca aaaccgttaa aattcaaaag ctcatttgca tattaacttt tgtttacttt 30960
gtggggtata ttattgatga tg 30982
<210> 10
<211> 31932
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr12.RSVF-2A-GLuc
<400> 10
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gactagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ttggccgtgc tcttcctgac gggtaggtgt 1320
cccctaacct agggagccaa ccatcggggg gccttctccc taaatccccg tggcccaccc 1380
tcctgggcag aggcagcagg tttctcactg gccccctctc ccccacctcc aagcttggcc 1440
tttcggctca gatctcagcc cacagctggc ctgatctggg tctcccctcc caccctcagg 1500
gagccaggct cggcatttcg tcgacatgga actgctgatc ctgaaggcca acgccatcac 1560
caccatcctg accgccgtga ccttctgctt cgccagcggc cagaacatca ccgaggaatt 1620
ctaccagagc acctgtagcg ccgtgtccaa gggctacctg agcgccctgc ggaccggctg 1680
gtacaccagc gtgatcacca tcgagctgag caacatcaaa aagaacaagt gcaacggcac 1740
cgacgccaaa atcaagctga tcaagcagga actggacaag tacaagaacg ccgtgaccga 1800
gctgcagctg ctgatgcaga gcacccccgc caccaacaac cgggccagac gggagctgcc 1860
ccggttcatg aactacaccc tgaacaacgc caaaaagacc aacgtgaccc tgagcaagaa 1920
gcggaagcgg cggttcctgg gcttcctgct gggcgtgggc agcgccattg ctagcggagt 1980
ggctgtgtct aaggtgctgc acctggaagg cgaagtgaac aagatcaagt ccgccctgct 2040
gagcaccaac aaggccgtgg tgtccctgag caacggcgtg tccgtgctga ccagcaaggt 2100
gctggatctg aagaactaca tcgacaagca gctgctgccc atcgtgaaca agcagagctg 2160
cagcatcagc aacatcgaga cagtgatcga gttccagcag aagaacaacc ggctgctgga 2220
aatcacccgc gagttcagcg tgaacgccgg cgtgaccacc cccgtgtcca cctacatgct 2280
gaccaacagc gagctgctga gcctgatcaa cgacatgccc atcaccaacg accagaaaaa 2340
gctgatgagc aacaacgtgc agatcgtgcg gcagcagagc tactccatca tgtccatcat 2400
caaagaagag gtgctggcct acgtggtgca gctgcccctg tacggcgtga tcgacacccc 2460
ctgctggaag ctgcacacca gccccctgtg caccaccaac accaaagagg gcagcaacat 2520
ctgcctgacc cggaccgacc ggggctggta ctgcgataat gccggcagcg tgtcattctt 2580
tccacaagcc gagacatgca aggtgcagag caaccgggtg ttctgcgaca ccatgaacag 2640
cctgaccctg cccagcgagg tgaacctgtg caacgtggac atcttcaacc ctaagtacga 2700
ctgcaagatc atgacctcca agaccgacgt gtccagctcc gtgatcacct ccctgggcgc 2760
catcgtgtcc tgctacggca agaccaagtg caccgccagc aacaagaacc ggggcatcat 2820
caagaccttc agcaacggct gcgactacgt gtccaacaag ggcgtggaca ccgtgtccgt 2880
gggcaacacc ctgtactacg tgaacaaaca ggaaggcaag agcctgtacg tgaagggcga 2940
gcccatcatc aacttctacg accccctggt gttccccagc gacgagttcg acgccagcat 3000
cagccaggtc aacgagaaga tcaaccagag cctggccttc atcagaaaga gcgacgagct 3060
gctgcacaat gtgaatgccg tgaagtccac caccaatatc atgatcacca caatcatcat 3120
cgtgatcatc gtcatcctgc tgtccctgat cgccgtgggc ctgctgctgt actgcaaggc 3180
ccggtccacc cctgtgaccc tgtccaagga ccagctgagc ggcatcaaca atatcgcctt 3240
ctccaacgga cgcgtgaccg agctgcttta ccggatgaag cgggctgaga catattgccc 3300
gagacccctg ttggcaatcc atcctactga ggctcgccac aaacagaaaa tcgtggcccc 3360
cgtcaaacag acactcaatt ttgacttgtt gaaacttgca ggagatgttg agtcaaaccc 3420
cgggcctatg ggcgtcaagg tcctgttcgc tctgatttgt atcgctgtcg ctgaagctaa 3480
gccaaccgag aataatgaag actttaatat cgtggccgtg gcttctaact tcgctaccac 3540
agacctggat gcagacaggg gaaagctgcc aggcaagaaa ctgcccctgg aggtcctgaa 3600
ggagatggaa gcaaatgccc ggaaagccgg gtgcacaaga ggatgcctga tttgtctgag 3660
ccacatcaag tgcactccta agatgaagaa gttcatcccc ggccggtgcc atacctacga 3720
gggcgataag gaatccgccc agggaggaat cggagaggct atcgtggata ttcccgaaat 3780
ccctggcttc aaagacctgg agcccatgga acagtttatt gcacaggtgg atctgtgcgt 3840
cgactgtact accggatgcc tgaagggact ggcaaacgtc cagtgtagcg acctgctgaa 3900
gaaatggctg cctcagcgat gtgctacatt tgccagcaag attcagggcc aggtggacaa 3960
gattaaggga gcaggaggcg actgataatt ctagacgaga tccgaacttg tttattgcag 4020
cttataatgg ttacaaataa agcaatagca tcacaaattt cacaaataaa gcattttttt 4080
cactgcattc tagttgtggt ttgtccaaac tcatcaatgt atcttatcat gtctagatcc 4140
aggtaggttt gagtagtggg cgtggctaag gtgactataa aggcgggtgt cttacgaggg 4200
tctttttgct tttctgcaga catcatgaac gggactggcg gggccttcga aggggggctt 4260
tttagccctt atttgacaac ccgcctgccg ggatgggccg gagttcgtca gaatgtgatg 4320
ggatcgacgg tggatgggcg cccagtgctt ccagcaaatt cctcgaccat gacctacgcg 4380
accgtgggga actcgtcgct cgacagcacc gccgcagccg cggcagccgc agccgccatg 4440
acagcgacga gactggcctc gagctacatg cccagcagcg gtagtagccc ctctgtgccc 4500
agttccatca tcgccgagga gaaactgctg gccctgctgg ccgagctgga agccctgagc 4560
cgccagctgg ccgccctgac ccagcaggtg tccgagctcc gcgaacagca gcagcagcaa 4620
aataaatgat tcaataaaca cagattctga ttcaaacagc aaagcatctt tattatttat 4680
tttttcgcgc gcggtaggcc ctggtccacc tctcccgatc attgagagtg cggtggattt 4740
tttccaggac ccggtagagg tgggattgga tgttgaggta catgggcatg agcccgtccc 4800
gtgggtggag gtagcaccac tgcatggcct cgtgctctgg ggtcgtgttg tagatgatcc 4860
agtcatagca ggggcgctgg gcgtggtgct ggatgatgtc cttgaggagg agactgatgg 4920
ccacggggag ccccttggtg taggtgttgg caaaacggtt gagctgggag ggatgcatgc 4980
ggggggagat gatgtgcagt ttggcctgga tcttgaggtt ggcgatgttg ccacccagat 5040
cccgccgggg gttcatgttg tgcaggacca ccagaacggt gtagcccgtg cacttgggga 5100
acttgtcatg caacttggaa gggaatgcgt ggaagaattt ggagacgccc ttgtgcccgc 5160
ccaggttttc catgcactca tccatgatga tggcaatggg cccgtgggct gcggctttgg 5220
caaagacgtt tctggggtca gagacatcgt aattatgctc ctgggtgaga tcatcataag 5280
acattttaat gaatttgggg cggagggtgc cagattgggg gacgatggtt ccctcgggcc 5340
ccggggcgaa gttcccctcg cagatctgca tctcccaggc tttcatctcg gaggggggga 5400
tcatgtccac ctgcggggcg atgaaaaaaa cggtttccgg ggcgggggtg atgagctgcg 5460
aggagagcag gtttctcaac agctgggact tgccgcaccc ggtcgggccg tagatgaccc 5520
cgatgacggg ttgcaggtgg tagttcaagg acatgcagct gccgtcgtcc cggaggaggg 5580
gggccacctc gttgagcttg tctctgactt ggaggttttc ccggacgagc tcgccgagga 5640
ggcggtcccc gcccagcgag agaagctctt gcagggaagc aaagtttttc aggggcttga 5700
gcccgtcggc catgggcatc ttggcgaggg tctgcgagag gagctccagg cggtcccaga 5760
gctcggtgac gtgctctacg gcatctcgat ccagcagact tcctcgtttc gggggttggg 5820
acgactgcga ctgtagggca cgagacgatg ggcgtccagc gcggccagcg tcatgtcctt 5880
ccagggtctc agggtccgcg tgagggtggt ctccgtcacg gtgaaggggt gggccgcggg 5940
ctgggcgctt gcaagggtgc gcttgagact catcctgctg gtgctgaaac gggcacggtc 6000
ttcgccctgc gcgtcggcga gatagcagtt gaccatgagc tcgtagttga gggcctcggc 6060
ggcgtggccc ttggcgcgga gcttgccctt ggaagagcgc ccgcaggcgg gacagaggag 6120
ggattgcagg gcgtagagct tgggcgcgag aaagacggac tcgggggcga aggcgtccgc 6180
tccgcagtgg gcgcagacgg tctcgcactc gactagccag gtgagctcgg gctgctcggg 6240
gtcaaaaacc agttttcccc cgttcttttt gatgcgcttc ttacctcgcg tctccatgag 6300
tctgtgtccg cgctcggtga caaacaggct gtctgtgtcc ccgtagacgg acttgatggg 6360
cctgtcctgc aggggcgtcc cgcggtcctc ctcgtagaga aactcagacc actctgagac 6420
gaaggcgcgc gtccacgcca agacaaagga ggccacgtgc gaggggtagc ggtcgttgtc 6480
caccaggggg tccacctttt ccacggtatg caggcacatg tccccctcct ccgcatccaa 6540
gaaggtgatt ggcttgtagg tgtaggccac gtgacctggg gttcccgacg ggggggtata 6600
aaagggggcg ggtctgtgct cgtcctcact ctcttccgcg tcgctgtcca cgagcgccag 6660
ctgttggggt aggtattccc tctcaagagc gggcatgacc tcggcactca ggttgtcagt 6720
ttctagaaac gaggaggatt tgatgtgggc ctgccctgcc gcgatgcttt ttaggagact 6780
ttcatccatc tggtcagaaa agactatttt tttattgtca agcttggtgg cgaaggagcc 6840
atagagggcg tttgagagaa gcttggcgat ggatctcatg gtctgatttt tgtcacggtc 6900
ggcgcgctcc ttggccgcga tgttgagctg gacatattcg cgcgcgacac acttccattc 6960
ggggaagacg gtggtgcgct cgtcgggcac gatcctgacg cgccagccgc ggttatgcag 7020
ggtgaccagg tccacgctgg tggccacctc gccgcgcagg ggctcgttgg tccagcagag 7080
tctgccgccc ttgcgcgagc agaacggggg cagcacatca agcagatgct cgtcaggggg 7140
gtccgcatcg atggtgaaga tgcccggaca gagttccttg tcaaaataat cgatttttga 7200
ggatgcatcg tccaaggcca tctgccactc gcgggcggcc agcgctcgct cgtaggggtt 7260
gaggggcgga ccccaaggca tgggatgcgt gagggcggag gcgtacatgc cgcagatgtc 7320
atagacatag atgggctccg agaggatgcc gatgtaggtg ggatagcagc gccccccgcg 7380
gatgcttgcg cgcacgtagt catacaactc gtgcgagggg gccaagaagg cggggccgag 7440
attggtgcgc tggggctgct cggcgcggaa gacgatctgg cgaaagatgg cgtgcgagtt 7500
ggaggagatg gtgggccgtt ggaagatgtt aaagtgggcg tgaggcaggc ggaccgagtc 7560
gcggatgaag tgcgcgtagg agtcttgcag cttggcgacg agctcggcgg tgacgaggac 7620
gtccatggcg cagtagtcca gcgtttcgcg gatgatgtca taactcgcct ctcctttctt 7680
ctcccacagc tcgcggttga gggcgtattc ctcgtcatcc ttccagtact cccggagcgg 7740
gaatcctcga tcgtccgcac ggtaagagcc cagcatgtag aaatggttca cggccttgta 7800
gggacagcag cccttctcca cggggagggc gtaagcttga gcggccttgc ggagcgaggt 7860
gtgcgtcagg gcaaaggtgt ccctgaccat gactttcaag aactggtact tgaagtccga 7920
gtcgtcgcag ccgccgtgct cccagagctc gaaatcggtg cgcttcttcg agagggggtt 7980
aggcagagcg aaagtgacgt cattgaagag aatcttgcct gcccgcggca tgaaattgcg 8040
ggtgatgcgg aaagggcccg ggacggaggc tcggttgttg atgacctggg cggcgaggac 8100
gatctcgtca aagccgttga tgttgtgccc gacgatgtag agttccatga atcgcgggcg 8160
gcctttgatg tgcggcagct ttttgagctc ctcgtaggtg aggtcctcgg ggcattgcag 8220
gccgtgctgc tcgagcgccc actcctggag atgtgggttg gcttgcatga aggaagccca 8280
gagctcgcgg gccatgaggg tctggagctc gtcgcgaaag aggcggaact gctggcccac 8340
ggccatcttt tctggggtga cgcagtagaa ggtgaggggg tcccgctccc agcgatccca 8400
gcgtaaacgc acggcgagat cgcgagcgag ggcgaccagc tctgggtccc cggagaattt 8460
catgaccagc atgaagggga cgagctgctt gccgaaggac cccatccagg tgtaggtttc 8520
tacatcgtag gtgacaaaga gccgctccgt gcgaggatga gagccgattg ggaagaactg 8580
gatttcctgc caccagttgg acgagtggct gttgatgtga tgaaagtaga aatcccgccg 8640
gcgaaccgag cactcgtgct gatgcttgta aaagcgtccg cagtactcgc agcgctgcac 8700
gggctgtacc tcatccacga gatacacagc gcgtcccttg aggaggaact tcaggagtgg 8760
cggccctggc tggtggtttt catgttcgcc tgcgtgggac tcaccctggg gctcctcgag 8820
gacggagagg ctgacgagcc cgcgcgggag ccaggtccag atctcggcgc ggcgggggcg 8880
gagagcgaag acgagggcgc gcagttggga gctgtccatg gtgtcgcgga gatccaggtc 8940
cgggggcagg gttctgaggt tgacctcgta gaggcgggtg agggcgtgct tgagatgcag 9000
atggtacttg atttctacgg gtgagttggt ggtcgtgtcc acgcattgca tgagcccgta 9060
gctgcgcggg gccacgaccg tgccgcggtg cgcttttaga agcggtgtcg cggacgcgct 9120
cccggcggca gcggcggttc cggccccgcg ggcaggggcg gcagaggcac gtcggcgtgg 9180
cgctcgggca ggtcccggtg ctgcgccctg agagcgctgg cgtgcgcgac gacgcggcgg 9240
ttgacatcct ggatctgccg cctctgcgtg aagaccacgg gccccgtgac tttgaacctg 9300
aaagacagtt caacagaatc aatctctgcg tcattgacgg cggcctgacg caggatctct 9360
tgcacgtcgc ccgagttgtc ctggtaggcg atctcggaca tgaactgttc gatctcctcc 9420
tcctggagat cgccgcggcc cgcgcgctcc acggtggcgg cgaggtcatt ggagatgcga 9480
cccatgagct gcgagaaggc gcccaggccg ctctcgttcc agacgcggct gtagaccacg 9540
tccccgtcgg cgtcgcgcgc gcgcatgacc acctgcgcga ggttgagctc cacgtgccgc 9600
gcaaagacgg cgtagttgcg caggcgctgg aagaggtagt tgagggtggt ggcgatgtgc 9660
tcggtgacga agaagtacat gatccagcgg cgcaggggca tctcgctgat gtcgccgatg 9720
gcttccagcc tttccatggc ctcgtagaag tccacggcga agttgaaaaa ctgggcgttg 9780
cgggccgaga ccgtgagctc gtcttccagg agccggatga gttcggcgat ggtggcgcgc 9840
acctcgcgct cgaaatcccc gggggcctcc tcctcttcct cttcttccat gacgacctct 9900
tcttctattt cttcctctgg gggcggtggt ggtggcgggg gccgacgacg acggcgacgc 9960
accgggagac ggtcgacgaa gcgctcgatc atctccccgc ggcggcgacg catggtttcg 10020
gtgacggcgc gaccccgttc gcgaggacgc agcgtgaaga cgccgccggt catctcccgg 10080
taatggggcg ggtccccatt gggcagcgat agggcgctga cgatgcatct tatcaattgc 10140
ggtgtagggg acgtgagcgc gtcgagatcg accggatcgg agaatctttc gaggaaagcg 10200
tctagccaat cgcagtcgca aggtaagctc aaacacgtag cagccctgcg gacgctgtta 10260
gaattgcggt tgctgatgat gtaattgaag taggcgtttt tgaggcggcg gatggtggcg 10320
aggaggacca ggtccttggg tccagcttgc tggatgcgga gccgctcggc catgccccag 10380
gcctggccct gacaccggct caggttcttg tagtagtcat gcatgagcct ctcaatgtca 10440
tcactggctg aggcggagtc ttccatgcgg gtgaccccga cgcccctgag cggctgcacg 10500
agcgccaggt cggcgacgac gcgctcggcg aggatggcct gttgcacgcg ggtgagggtg 10560
tcctggaagt cgtccatgtc gacgaagcgg tgataggccc cggtgttgat ggtgtaggtg 10620
cagttggcca tgagcgacca gttgacggtc tgcaggcctg gctgcacgac ctcggagtac 10680
ctgagccgcg agaaggcgcg cgagtcgaag acgtagtcgt tgcaggtgcg cacgaggtac 10740
tggtatccga ctaggaagtg cggcggcggc tggcggtaga gcggccagcg ctgggtggcc 10800
ggcgcgcccg gggccaggtc ctcgagcatg aggcggtggt agccgtagag gtagcgggac 10860
atccaggtga tgccggcggc ggtggtggag gcgcgcggga actcgcggac gcggttccag 10920
atgttgcgca gcggcaggaa atagtccatg gtcggcacgg tctggccggt gagacgcgcg 10980
cagtcattga cgctctagag gcaaaaacga aagcggttga gcgggctctt cctccgtagc 11040
ctggcggaac gcaaacgggt taggccgcgt gtgtaccccg gttcgagtcc cctcgaatca 11100
ggctggagcc gcgactaacg tggtattggc actcccgtct cgacccgagc ccgatagccg 11160
ccaggatacg gcggagagcc ctttttgccg gccgagtggg gtcgctagac ttgaaagcga 11220
ccgaaaaccc tgccgggtag tggctcgcgc ccgtagtctg gagaagcatc gccagggttg 11280
agtcgcggca gaacccggtt cgaggacggc cgcggcgagc gggacttggt caccccgccg 11340
atataaagac ccacagccag ccgacttctc cagttacggg agcgagcccc cttttttctt 11400
tttgccagat gcatcccgtc ctgcgccaaa tgcgtcccac ccccccggcg accaccgcga 11460
ccgcggccgt agcaggcgcc ggcgctagcc agccaccaca gacagagatg gacttggaag 11520
agggcgaagg gctggcaaga ctgggggcgc cgtccccgga gcgacatccc cgcgtgcagc 11580
tgcagaagga cgtgcgcccg gcgtacgtgc ctacgcagaa cctgttcagg gaccgcagcg 11640
gggaggagcc cgaggagatg cgcgactgcc ggtttcgggc gggcagggag ctgcgcgagg 11700
gcctggaccg ccagcgcgtg ctgcgcgacg aggatttcga gccgaacgag cagacgggga 11760
tcagccccgc acgcgcgcac gtggcggcag ccaacctggt gacggcctac gagcagacgg 11820
tgaagcagga gcgcaacttc caaaagagtt tcaacaacca cgtgcgcacc ctgatcgcgc 11880
gcgaggaggt ggccctgggc ctgatgcacc tgtgggacct ggcggaggcc atcgtgcaga 11940
acccggacag caagcctctg acggcgcagc tgttcctggt ggtgcagcac agcagggaca 12000
acgaggcgtt cagggaggcg ctgctgaaca tcgccgagcc cgagggtcgc tggctgctgg 12060
agctgattaa catcttgcag agcatcgtag tgcaggagcg cagcctgagc ctggccgaga 12120
aggtggcggc gatcaactac tcggtgctga gcctgggcaa gttttacgcg cgcaagattt 12180
acaagacgcc gtacgtgccc atagacaagg aggtgaagat agacagcttt tacatgcgca 12240
tggcgctcaa ggtgctgacg ctgagcgacg acctgggcgt gtaccgcaac gaccgcatcc 12300
acaaggccgt gagcacgagc cggcggcgcg agctgagcga ccgcgagctg atgctgagtc 12360
tgcgccgggc gctggtaggg ggcgccgccg gcggcgagga gtcctacttc gacatgggtg 12420
cggacctgca ttggcagccg agccggcgcg ccttggaggc cgcctacggt tcagaggact 12480
tggatgagga agaggaagag gaggaggatg cacccgctgc ggggtactga cgcctccgtg 12540
atgtgttttt agatgtccca gcaagccccg gaccccgcca taagggcggc gctgcaaagc 12600
cagccgtccg gtctagcatc ggacgactgg gaggccgcga tgcaacgcat catggccctg 12660
acgacccgca accccgagtc ctttagacaa cagccgcagg ccaacagact ctcggccatt 12720
ctggaggcgg tggtcccctc tcggaccaac cccacgcacg agaaggtgct ggcgatcgtg 12780
aacgcgctgg cggagaacaa ggccatccgt cccgacgagg ccgggctggt gtacaacgcc 12840
ctgctggagc gcgtgggccg ctacaacagc acgaacgtgc agtccaacct ggatcggctg 12900
gtgacggacg tgcgcgaggc cgtggcgcag cgcgagcggt tcaagaacga gggcctgggc 12960
tcgctggtgg cgctgaacgc cttcctggcg acgcagccgg cgaacgtgcc gcgcgggcag 13020
gacgattaca ccaactttat cagcgcgctg cggctgatgg tgaccgaggt gccccagagc 13080
gaggtgtacc agtctggccc ggactacttt ttccagacga gccggcaggg cttgcagacg 13140
gtgaacctga gccaggcttt caagaatctg cgcgggctgt ggggcgtgca ggcgcccgtg 13200
ggcgaccggt caacggtgag cagcttgctg acgcccaact cgcggctgct gctgctgctg 13260
atcgcgccct tcaccgacag cggcagcgtg aaccgcaact cgtacctggg ccatctgctg 13320
acgctgtacc gcgaggccat aggccaggcg caggtggacg agcagacctt ccaggagatc 13380
actagcgtga gccgcgcgct ggggcagaac gacaccgaca gtctgagggc caccctgaac 13440
tttttgctga ccaatagaca gcagaagatc ccggcgcagt acgcactgtc ggccgaggag 13500
gaaaggattc tgagatatgt gcagcagagc gtagggctgt tcctgatgca ggagggtgcc 13560
acccccagcg ccgcgctgga catgaccgcg cgcaacatgg aacctagcat gtacgccgcc 13620
aaccggccgt tcatcaataa gctgatggac tacttgcacc gcgcggcggc catgaacacg 13680
gactacttta ccaacgccat cctgaacccg cactggctcc cgccgccggg gttctacacg 13740
ggcgagtacg acatgcccga ccccaacgac gggttcctgt gggacgacgt ggacagcgcg 13800
gtgttctcgc cgacctttca aaagcgccag gaggcgccgc cgagcgaggg cgcggtgggg 13860
aggagcccct ttcctagctt agggagtttg catagcttgc cgggctcggt gaacagcggc 13920
agggtgagcc ggccgcgctt gctgggcgag gacgagtacc tgaacgactc gctgctgcag 13980
ccgccgcggg ccaagaacgc catggccaat aacgggatag agagtctggt ggacaaactg 14040
aaccgctgga agacctacgc tcaggaccat agggacgcgc ccgcgccgcg gcgacagcgc 14100
cacgaccggc agcggggcct ggtgtgggac gacgaggact cggccgacga tagcagcgtg 14160
ttggacttgg gcgggagcgg tggggtcaac ccgttcgcgc atctgcagcc caaactgggg 14220
cgacggatgt tttgaatgaa ataaaactca ccaaggccat agcgtgcgtt ctcttccttg 14280
ttagagatga ggcgcgcggt ggtgtcttcc tctcctcctc cctcgtacga gagcgtgatg 14340
gcgcaggcga ccctggaggt tccgtttgtg cctccgcggt atatggctcc tacggagggc 14400
agaaacagca ttcgttactc ggagctggct ccgcagtacg acaccactcg cgtgtacttg 14460
gtggacaaca agtcggcgga catcgcttcc ctgaactacc aaaacgacca cagcaacttc 14520
ctgaccacgg tggtgcagaa caacgatttc acccccgccg aggccagcac gcagacgata 14580
aattttgacg agcggtcgcg gtggggcggt gatctgaaga ccattctgca cactaacatg 14640
cccaatgtga acgagtacat gttcaccagc aagtttaagg cgcgggtgat ggtgtctagg 14700
aagcatccag agggggtagt tgaaacagat ttgagtcagg ataagcttga atatgagtgg 14760
tttgagttta ccctgcccga gggaaacttt tccgagacca tgaccataga cctgatgaac 14820
aacgccatct tggaaaacta cttgcaagtg gggcggcaga atggcgtgct ggagagcgat 14880
atcggagtca agtttgacag cagaaatttc aagctgggct gggacccggt gaccaagctg 14940
gtgatgccag gggtctacac ctacgaggcc ttccacccgg acgtggtgct gctgccgggc 15000
tgcggggtgg acttcaccga gagccgcctg agcaacctcc tgggcattcg caagaagcaa 15060
cctttccaag agggcttcag aatcatgtat gaggatctag aaggtggcaa catccccgcc 15120
ctccttgatg tgcccaagta cttggaaagc aagaagaaag ttgaagacga aactaaaaat 15180
gcagctgcgg ccacagccga tacaaccact aggggtgata catttgcaac tccagcgcaa 15240
gagacagcag ctgataagaa ggtagaagtc ttgcccattg aaaaggatga gagtggtaga 15300
agttacaacc tgatccaggg gacccacgac acgctgtacc gcagttggta cctgtcctat 15360
acctacgggg accccgagaa gggggtgcag tcgtggacgc tgctcaccac cccggacgtt 15420
acctgcggcg cggagcaagt ctactggtca ctgccggacc tcatgcaaga ccccgtcacc 15480
ttccgctcca cccagcaagt cagcaactac cccgtggtcg gcgccgagct catgcccttc 15540
cgcgccaaga gcttttacaa cgacctcgcc gtctactccc agctcatccg cagctacacc 15600
tccctcaccc acgtcttcaa ccgcttcccc gacaaccaga tcctctgccg cccgcccgcg 15660
cccaccatca ccaccgtcag tgaaaacgtg cctgctctca cagatcacgg gacgctaccg 15720
ctgcgcagca gtatccgcgg agtccagcga gtgaccgtca ctgacgcccg tcgccgcacc 15780
tgtccctacg tctacaaggc cctgggcata gtcgcgccgc gcgtgctttc cagtcgcacc 15840
ttctaaaaaa atgtctattc tcatctcgcc cagcaataac accggctggg gtcttactag 15900
acccagcacc atgtacggag gagccaagaa gcgctcccag cagcaccccg tccgcgtccg 15960
cggccacttc cgcgctccct ggggcgcata caagcgcggg cggacttcca ccgccgccgt 16020
gcgcaccacc gtcgacgacg tcatcgactc ggtggtcgcc gacgcgcgca actatacccc 16080
cgccccctcc accgtggacg cggtcatcga cagcgtggtg gccgacgcgc gcgactatgc 16140
cagacgcaag agccggcggc gacggatcgc caggcgccac cggagcacgc ccgccatgcg 16200
cgccgcccgg gctctgctgc gccgcgccag acgcacgggc cgccgggcca tgatgcgagc 16260
cgcgcgccgc gctgccactg cacccacccc cgcaggcagg actcgcagac gagcggccgc 16320
cgccgccgct gcggccatct ctagcatgac cagacccagg cgcggaaacg tgtactgggt 16380
gcgcgactcc gtcacgggcg tgcgcgtgcc cgtgcgcacc cgtcctcctc gtccctgatc 16440
taatgcttgt gtcctccccc gcaagcgacg atgtcaaagc gcaaaatcaa ggaggagatg 16500
ctccaggtcg tcgccccgga gatttacgga ccaccccagg cggaccagaa accccgcaaa 16560
atcaagcggg ttaaaaaaaa ggatgaggtg gacgaggggg cagtagagtt tgtgcgcgag 16620
ttcgctccgc ggcggcgcgt aaattggaag gggcgcaggg tgcagcgcgt gttgcggccc 16680
ggcacggcgg tggtgttcac gcccggcgag cggtcctcgg tcaggagcaa gcgtagctat 16740
gacgaggtgt acggcgacga cgacatcctg gaccaggcgg cggagcgggc gggcgagttc 16800
gcctacggga agcggtcgcg cgaagaggag ctgatctcgc tgccgctgga cgaaagcaac 16860
cccacgccga gcctgaagcc cgtgaccctg cagcaggtgc tgccccaggc ggtgctgctg 16920
ccgagccgcg gggtcaagcg cgagggcgag agcatgtacc cgaccatgca gatcatggtg 16980
cccaagcgcc ggcgcgtgga ggacgtgctg gacaccgtga aaatggatgt ggagcccgag 17040
gtcaaggtgc gccccatcaa gcaggtggcg ccgggcctgg gcgtgcaaac cgtggacatt 17100
cagatcccca ccgacatgga tgtcgacaaa aaaccctcga ccagcatcga ggtgcaaacc 17160
gacccctggc tcccagcctc caccgctacc gtctccactt ctaccgccgc cacggctacc 17220
gagcctccca ggaggcgaag atggggcgcc gccagccggc tgatgcccaa ctacgtgttg 17280
catccttcca tcatcccgac gccgggctac cgcggcaccc ggtactacgc cagccgccgg 17340
cgcccagcca gcaaacgccg ccgccgcacc gccacccgcc gccgtctggc ccccgcccgc 17400
gtgcgccgcg tgaccacgcg ccggggccgc tcgctcgttc tgcccaccgt gcgctaccac 17460
cccagcatcc tttaatccgt gtgctgtgat actgttgcag agagatggct ctcacttgcc 17520
gcctgcgcat ccccgtcccg aattaccgag gaagatcccg ccgcaggaga ggcatggcag 17580
gcagcggcct gaaccgccgc cggcggcggg ccatgcgcag gcgcctgagt ggcggctttc 17640
tgcccgcgct catccccata atcgccgcgg ccattggcac gatcccgggc atagcttccg 17700
ttgcgctgca ggcgtcgcag cgccgttgat gtgcgaataa agcctcttta gactctgaca 17760
cacctggtcc tgtatatttt tagaatggaa gacatcaatt ttgcgtccct ggctccgcgg 17820
cacggcacgc ggccgttcat gggcacctgg aacgagatcg gcaccagcca gctgaacggg 17880
ggcgccttca attggagcag tgtctggagc gggcttaaaa atttcggctc gacgctccgg 17940
acctatggga acaaggcctg gaatagtagc acggggcagt tgttgaggga aaagctcaaa 18000
gaccagaact tccagcagaa ggtggtggac gggctggcct cgggcattaa cggggtggtg 18060
gacatcgcga accaggccgt gcagcgcgag ataaacagcc gcctggaccc gcgaccgccc 18120
acggtggtgg agatggaaga tgcaactctt ccgccgccca agggcgagaa gcggccgcgg 18180
cccgacgcgg aggagacgat cctgcaggtg gacgagccgc cctcgtacga ggaggccgtc 18240
aaggccggca tgcccaccac gcgcatcatc gcgccgctgg ccacgggtgt aatgaaaccc 18300
gccacccttg acctgcctcc accacccgcg cccgctccac cgaaggcaac tccggttgtg 18360
caggcccccc cggtggcgac cgccgtgcgc cgcgtccccg cccgccgcca ggcccagaac 18420
tggcagagca cgctgcacag tatcgtgggc ctgggagtga aaagtctgaa gcgccgccga 18480
tgctattgag agagaggaaa gaggacacta aagggagagc ttaacttgta tgtgccttac 18540
cgccagagaa cgcgcgaaga tggccacccc ctcgatgatg ccgcagtggg cgtacatgca 18600
catcgccggg caggacgcct cggagtacct gagcccgggt ctggtgcagt ttgcccgcgc 18660
caccgacacg tacttcagcc tgggcaacaa gtttaggaac cccacggtgg ccccgaccca 18720
cgatgtgacc acggaccggt cccagcgtct gacgctgcgc ttcgtgcccg tggatcgcga 18780
ggacaccacg tactcgtaca aggcgcgctt cactctggcc gtgggcgaca accgggtgct 18840
agacatggcc agcacttact ttgacatccg cggcgtcctg gaccgcggtc ccagcttcaa 18900
accctactcg ggcacggcct acaacagcct ggctcccaag ggtgccccca atcccagcca 18960
gtgggagcaa aatgaaacca atgttaataa aacacacacc tttgggatgg cagccatgaa 19020
aggagaagct attgacaaaa atggtctgca aattggaact gacgcggcgg atcaggataa 19080
accaatttat gcagataaaa ctttccagcc agaacctcaa gtaggagagg aagactggat 19140
tgataaagca gatttctatg gcggaagagc tcttaaaaaa gacactaaaa tgaaaccatg 19200
ctatggatct tttgctagac ctactaatga gaaaggaggt caggcaaagt tcaaaccagt 19260
taatgaagga gaacaaccta aagatctgga tatagatatg aacttctttg acccaaccac 19320
tattaacaca ccagatgtag tgctgtacac tgaaaatgtt aatcttgaaa caccagacac 19380
tcatgtggtt tacaaggcag gaacttcaga tgacagttct gaggtcaatt tggctcagca 19440
gtccatgcca aacagaccca actacattgg ctttagggac aactttgtag gtctcatgta 19500
ttacaacagc accggaaata tgggtgtgct ggctggtcag gcttctcagt tgaacgctgt 19560
ggtcgacttg caagacagaa acaccgagtt atcttaccag ctattgctag attctctggg 19620
tgacagaacc agatacttta gcatgtggaa ctctgcggtg gacagttacg atccagatgt 19680
caggatcatt gaaaatcacg gtgtggaaga tgaacttcca aactattgct tcccattgga 19740
tggtgtgggc actaatactg cataccaagg cgttaaagtt aagacaacta atggaaacga 19800
cacgtgggaa aaagatgaaa ctgtttatga gtttaatcaa attggcaagg gggatatcta 19860
tgccatggag atcaacctgc aggccaacct gtggaagagt tttctgtact cgaacgtggc 19920
cctgtacctg cccgactcct acaagtacac gccggccaac gtcaagctgc ccgccaacac 19980
caacacctac gagtacatga acggccgcgt ggtagccccc tcgctggtgg acgcctacat 20040
caacatcggc gcccgctggt cgttggatcc catggacaac gtcaacccct tcaaccacca 20100
ccgcaatgcg ggcctgcgct accgctccat gctgctgggc aacggccgct acgtgccctt 20160
ccacatccaa gtgccccaaa agttctttgc catcaagaac ctgctcctgc tcccgggctc 20220
ctacacctac gagtggaact tccgcaagga cgtcaacatg atcctgcaga gttccctcgg 20280
caacgacctg cgcgtcgacg gcgcctccgt ccgcttcgac agcgtcaacc tatacgccac 20340
tttcttcccc atggcgcaca acaccgcttc aaccttggaa gccatgctgc gcaacgacac 20400
caacgaccag tccttcaacg actacctctc ggccgccaac atgctctacc ccatcccggc 20460
caaggccacc aacgtgccca tctccatccc atcgcgcaac tgggccgcct tccgcggctg 20520
gagtttcacc cggctcaaga ccaaggaaac tccttccctc ggctcgggtt tcgaccccta 20580
ctttgtctac tcgggctcca tcccctacct cgacgggacc ttctacctca accacacctt 20640
caagaaggtc tccatcatgt tcgactcctc ggtcagctgg cccggcaacg accggctgct 20700
cacgccgaac gagttcgaga tcaagcgcag cgtcgacggg gagggctaca acgtggccca 20760
atgcaacatg accaaggact ggttcctcgt ccagatgctc tcccactaca acatcggcta 20820
ccagggcttc cacgtgcccg agggctacaa ggaccgcatg tactccttct tccgcaactt 20880
ccagcccatg agcaggcagg tggtcgatga gatcaactac aaggactaca aggccgtcac 20940
cctgcccttc cagcacaata actcgggctt caccggctac ctcgcaccca ccatgcgcca 21000
ggggcagccc taccccgcca acttccccta cccgctcatc ggtcagacag ccgtgccctc 21060
cgtcacccag aaaaagttcc tctgcgacag ggtcatgtgg cgcatcccct tctccagcaa 21120
cttcatgtcc atgggcgccc tcaccgacct gggtcagaac atgctctacg ccaactcggc 21180
ccacgcgctc gacatgacct tcgaggtgga ccccatggat gagcccaccc tcctctatct 21240
tctcttcgaa gttttcgacg tggtcagagt acaccagccg caccgcggcg tcatcgaggc 21300
cgtctacctg cgcacgccct tctccgccgg caacgccacc acctaagcat gagcggctcc 21360
agcgaacgag agctcgcggc catcgtgcgc gacctgggct gcgggcccta ctttttgggc 21420
acccacgaca agcgcttccc gggctttctc gccggcgaca agctggcctg cgccatcgtc 21480
aacacggccg gccgcgagac cggaggcgtg cactggctcg ccttcggctg gaacccgcgc 21540
tcgcgcacct gctacatgtt cgaccccttt gggttctcgg accgccggct caagcagatt 21600
tacagcttcg agtacgaggc catgctgcgc cgcagcgccc tggcctcctc gcccgaccgc 21660
tgtctcagcc tcgagcagtc cactcagacc gtgcaggggc ccgactccgc cgcctgcgga 21720
ctcttctgtt gcatgttctt gcatgccttc gtgcactggc ccgaccgacc catggacgga 21780
aaccccacca tgaacttgct gacgggggtg cccaacggca tgctacaatc gccacaggtg 21840
ctgcccaccc tcaggcgcaa ccaggaggaa ctctaccgct tcctcgcgcg ccactcccct 21900
tactttcgct cccaccgcgc cgccatcgaa cacgccaccg cttttgacaa aatgaaacaa 21960
ctgcgtgtat ctcaataaac agcactttta ttttacatgc actggagtat atgcaagtta 22020
tttaaaagtc gaaggggttc tcgcgctcgt cgttgtgcgc cgcgctgggg agggccacgt 22080
tgcggtactg gtacttgggc tgccacttga actcggggat caccagtttg ggcactgggg 22140
tctcggggaa ggtctcgctc cacatgcgcc ggctcatctg cagggcgccc agcatgtccg 22200
gggcggagat cttgaaatcg cagttggggc cggtgctctg cgcgcgcgag ttgcggtaca 22260
cggggttgca gcactggaac accatcagac tggggtactt cacactagcc agcacgctct 22320
tgtcgctgat ctgatccttg tccagatcct cggcgttgct caggccgaac ggggtcatct 22380
tgcacagctg gcgtcccagg aagggcacgc tctgaggctt gtggttacac tcgcagtgca 22440
cgggcatcag catcatcccc gcgccgcgct gcatattcgg gtagagggcc ttgacaaagg 22500
ccgcgatctg cttgaaagct tgctgggcct tggccccctc gctgaaaaac aggccgcagc 22560
tcttcccgct gaactggtta ttcccacacc cggcatcctg cacgcagcag cgcgcgtcat 22620
ggctggtcag ttgcaccacg ctccgtcccc agcggttctg ggtcacctta gccttgctgg 22680
gctgctcctt caacgcgcgc tgcccgttct cgctggtcac atccatctcc accacgtggt 22740
ccttgtggat catcatcgtc ccgtgcagac acttgagctg gccttccacc tcggtgcagc 22800
cgtgatccca cagggcgcaa ccggtgcact cccagttctt gtgcgcaatc ccgctgtggc 22860
tgaagatgta accttgcaac atgcggccca tgatggtgct aaatgctttc tgggtggtga 22920
aggtcagttg catcccgcgg gcctcctcgt tcatccaggt ctggcacatc ttctggaaga 22980
tctcggtctg ctcgggcatg agcttgtaag catcgcgcag gccgctgtcg acgcggtagc 23040
gttccatcag cacgttcatg gtatccatgc ccttctccca ggacgagacc agaggcagac 23100
tcagagggtt gcgtacgttc aggacaccgg gggtcgcggg ctcgacgatg cgttttccgt 23160
ccttgccttc cttcaataga accggcggct ggctgaatcc cactcccacg atcacggcat 23220
cttcctgggg catctcttcg tcggggtcta ccttggtcac atgcttggtc tttctggctt 23280
gcttcttttt tggagggctg tccacgggga gcacgtcctc ctcggaagac ccggagccca 23340
cccgctgata ctttcggcgc ttggtgggca gaggaggtgg cggcgagggg ctcctctcct 23400
gctccggcgg atagcgcgcc gacccgtggc cccggggcgg agtggcctct cggcccatga 23460
accggcgcac gtcctgactg ccgccggcca ttgtttccta ggggaagatg gaggagcagc 23520
cgcgtaagca ggagcaggag gaggacttaa ccacccacga gcaacccaaa atcgagcagg 23580
acctgggctt cgaagagccg gctcgtctag aacccccaca ggatgaacag gagcacgagc 23640
aagacgcagg ccaggaggag accgacgctg ggctcgagca tggctacctg ggaggagagg 23700
aggatgtgct gctgaaacac ctgcagcgcc agtccctcat cctccgggac gccctggccg 23760
accggagcga aacccccctc agcgtcgagg agctgtgtcg ggcctacgag ctcaacctct 23820
tctcgccgcg cgtacccccc aaacgccagc ccaacggcac ctgcgagccc aacccgcgtc 23880
tcaacttcta tcccgtcttt gcggtccccg aagccctcgc cacctatcac atctttttca 23940
agaaccaaaa gatccccgtc tcctgccgcg ccaaccgcac cagcgccgac gcgctcctcg 24000
ctttggggcc cggcgcgcgc atacctgata tcgcttccct ggaagaggtg cccaagatct 24060
tcgaagggct cggtcgggac gagacgcgcg cggcgaacgc tctgaaagaa acagcagagg 24120
aagagggtca cactagcgcc ctggtagagt tggaaggcga caacgccagg ctggccgtgc 24180
tcaagcgcag cgtcgagctt acccacttcg cctaccccgc cgtcaacctc ccgcccaagg 24240
tcatgcgtcg catcatggat cagctcatca tgccccacat cgaggccctc gatgaaagtc 24300
aggagcagcg ccccgaggac gcccggcccg tggtcagcga cgagatgctc gcgcgctggc 24360
tcgggacccg cgacccccag gctttggaac agcggcgcaa actcatgctg gccgtggtcc 24420
tggtcaccct tgagctcgaa tgcatgcgcc gctttttcag cgaccccgag accctgcgca 24480
aggtcgagga gaccctgcac tacactttca ggcacggttt cgtcaggcag gcctgcaaga 24540
tctccaacgt ggagctgacc aacctggtct cctgcctggg gatcctgcac gagaaccgcc 24600
tgggccagac cgtgctccac tctaccctga agggcgaggc gcggcgggac tatgtccgcg 24660
actgcgtctt tctctttctc tgccacacat ggcaagcggc catgggcgtg tggcagcagt 24720
gtctcgagga cgagaaccta aaggagctgg acaagcttct tgctagaaac cttaaaaagc 24780
tgtggacggg cttcgacgag cgcaccgtcg cctcggacct ggccgagatc gtcttccccg 24840
agcgcctgag acagacgctg aaaggcgggc tgcccgactt catgagccag agcatgttgc 24900
aaaactaccg cactttcatt cttgagcgat caggcatcct gcccgccacc tgcaacgcct 24960
tcccctccga ctttgtaccg ctgagctacc gcgagtgtcc cccgccgctg tggagccact 25020
gctacctctt gcagctggcc aactacatcg cctaccactc ggacgtgatc gaggacgtga 25080
gcggcgaggg gctgctcgag tgccactgtc gctgcaacct gtgctccccg catcgctccc 25140
tggtctgcaa cccccagctc ctgagcgaga cccaggtcat cggtaccttc gagctgcaag 25200
gtccgcagga gtccaccgct ccgctgaaac tcacgccggg gttgtggact tccgcgtacc 25260
tgcgcaaatt tgtacccgaa gactaccacg cccatgagat aaagttcttt gaggaccaat 25320
cgcgtccgca gcacgcggat ctcacggcct gcgtcatcac ccagggcgcg atcctcgccc 25380
aattgcacgc catccaaaaa tcccgccaag agtttcttct gaaaaagggt agaggggtct 25440
acctggaccc ccagacgggc gaggtgctca acccgggtct cccccagcat gccgaggaag 25500
aagcaggagc cgctagtgga ggagatggaa gaagaatggg acagccaggc agaggaggac 25560
gaatgggagg aggagacaga ggaggaagaa ttggaagagg tggaagagga gcaggcaaca 25620
gagcagcccg tcgccgcacc atccgcgccg gcagccccgc cggtcacgga tacaacctcc 25680
gctccggtca agcctcctcg tagatgggat caagtgaagg gtgacggtaa gcacgagcgg 25740
cagggctacc gatcatggag ggcccacaaa gccgcgatca tcgcctgctt gcaagactgc 25800
ggggggaaca tcgctttcgc ccgccgctac ctgctcttcc accgcggggt gaacatcccc 25860
cgcaacgtgt tgcattacta ccgtcacctt cacagctaag aaaaagcaag tcaaaggagt 25920
cgccggagga ggaggaggag gcctgaggat cgcggcgaac gagcccttga ccaccaggga 25980
gctgaggaac cggatcttcc ccactcttta tgccattttt cagcagagtc gaggtcagca 26040
gcaagagctc aaagtaaaaa accggtctct gcgctcgctc acccgcagtt gcttgtacca 26100
caaaaacgaa gatcagctgc agcgcactct cgaagacgcc gaggctctgt tccacaagta 26160
ctgcgcgctc actcttaaag actaaggcgc gcccacccgg aaaaaaggcg ggaattacct 26220
catcgccacc atgagcaagg agattcccac cccttacatg tggagctatc agccccaaat 26280
gggcctggcc gcgggcgcct cccaggacta ctccacccgc atgaactggc tcagtgccgg 26340
cccctcgatg atctcacggg tcaacggggt ccgcagtcat cgaaaccaga tattgttgga 26400
gcaggcggcg gtcacctcca cgcccagggc aaagctcaac ccgcgtaatt ggccctccac 26460
cctggtgtat caggaaatcc ccgggccgac taccgtacta cttccgcgtg acgcactggc 26520
cgaagtccgc atgactaact caggtgtcca gctggccggc ggcgcttccc ggtgcccgct 26580
ccgcccacaa tcgggtataa aaaccctggt gatccgaggc agaggcacac agctcaacga 26640
cgagttggtg agctcttcga tcggtctgcg accggacgga gtgttccaac tagccggagc 26700
cgggagatcc tccttcactc ccaaccaggc ctacctgacc ttgcagagca gctcttcgga 26760
gcctcgctcc ggaggcatcg gaaccctcca gtttgtggag gagtttgtgc cctcggtcta 26820
cttcaacccc ttctcgggat cgccaggcct ctacccggac gagttcatac cgaacttcga 26880
cgcagtgaga gaagcggtgg acggctacga ctgaatgtcc catggtgact cggctgagct 26940
cgctcggttg aggcatctgg accactgccg ccgcctgcgc tgcttcgccc gggagagctg 27000
cggactcatc tactttgagt ttcccgagga gcaccccaac ggccctgcac acggagtgcg 27060
gatcaccgta gagggcacca ccgagtctca cctggtcagg ttcttcaccc agcaaccctt 27120
cctggtcgag cgggaccggg gcgccaccac ctacaccgtc tactgcatct gtccaacccc 27180
gaagttgcat gagaattttt gttgtactct ttgtggtgag tttaataaaa gctaaactct 27240
tgcaatactc tggaccttgt cgtcgtcaac tcaacgagac cgtctacctc accaaccaga 27300
ctgaggtaaa actcacctgc agaccacaca agacctatat catctggttc ttcgagaaca 27360
cctcatttgc agtctccaac actcactgca ctagtccatg aactgatgtt gattaaaagc 27420
ccaaaaacca atcagcccct tcccccattt ccccatcccc caattactca taaaaaataa 27480
atcattggaa ttaatcattc aataaagatc acttacttga aatctgaaag tatgtctctg 27540
gtgtagttgt tcagcagcac ctcggtaccc tcctcccagc tctggtactc cagtccccgg 27600
cgggcggcga acttcctcca caccttgaaa gggatgtcaa attcctggtc cacaattttc 27660
attgtcttcc ctctcagatg gcaaagaggc tccgggtgga agatgacttc aaccccgtct 27720
acccctatgg ctacgcgcgg aatcagaata tccccttcct cactcccccc tttgtctcct 27780
ccgatggatt caaaaacttc ccccctgggg tcctgtcact taaactggct gatccaatca 27840
ccatcaacaa tggggatgtc tcacttaagg tgggaggggg acttgctgta gagcaacaga 27900
ctggtaacct aagcgtaaac cctgatgcac ccttgcaagt tgcaagtgat aagctacagc 27960
ttgctctggc tcctccattc gaggtcagag atggaaagct tgctttaaag gcaggtaatg 28020
gattaaaagt actagataat tccattactg gattgactgg attattgaat acacttgtgg 28080
tattaactgg aaggggaata ggaacggagg aattaaaaaa tgacgatggt gtaacaaaca 28140
aaggagtcgg cttgcgtgta agacttggag atgacggcgg gctgacattt gataaaaagg 28200
gtgatttagt agcctggaat aaaaaagatg acaggcgcac cctgtggaca acccctgaca 28260
catctccaaa ttgcaaaatg agtacagaaa aggattctaa acttacgttg acacttacaa 28320
agtgtggaag tcaggttctg ggaaatgtat ctttacttgc agttacaggt gaatatcatc 28380
aaatgactgc tactacaaag aaggatgtaa aaatatcttt actatttgat gagaatggaa 28440
ttctattacc atcttcgtcc cttagcaaag attattggaa ttacagaagt gatgattcta 28500
ttgtatctca aaaatataat aatgcagttc cattcatgcc aaacctgaca gcttatccaa 28560
aaccaagcgc tcaaaatgca aaaaactatt caagaactaa aatcataagt aatgtctact 28620
taggtgctct tacctaccaa cctgtaatta tcactattgc atttaatcag gaaactgaaa 28680
atggatgtgc ttattctata acatttacct tcacttggca aaaagactat tctgcccaac 28740
agtttgatgt tacatctttt accttctcat atcttaccca agagaacaaa gacaaagact 28800
aataaaatgt tttgaactga atttatgaat ctttatttat ttttacacca gcacgggtag 28860
tcagtttccc accaccagcc catttcacag tgtaaacagt cctttctccc cggctggcct 28920
taaaaagcat catatcatgg gtaacagaca tattcttagg tgttatattc cacacggttt 28980
cctgtcgagc caaacgctca tcagtgatat taataaactc cccgggcagc tcacttaagt 29040
tcatgtcgct gtccagctgc tgagccacag gctgctgtcc aacttgcggt tgcttaacgg 29100
gcggcgaagg agaagtccac gcctacatgg gggtagagtc ataatcgtgc atcaggatag 29160
ggcggtggtg ctgcagcagc gcgcgaataa actgctgccg ccgccgctcc gtcctgcagg 29220
aatacaacat ggcagtggtc tcctcagcga tgattcgcac cgcccgcagc ataaggcgcc 29280
ttgtcctccg ggcacagcag cgcaccctga tctcacttaa atcagcacag taactgcagc 29340
acagcaccac aatattgttc aaaatcccac agtgcaaggc gctgtatcca aagctcatgg 29400
cggggaccac agaacccacg tggccatcat accacaagcg caggtagatt aagtggcgac 29460
ccctcataaa cacgctggac ataaacatta cctcttttgg catgttgtaa ttcaccacct 29520
cccggtacca tataaacctc tgattaaaca tggcgccatc caccaccatc ctaaaccagc 29580
tggccaaaac ctgcccgccg gctatacact gcagggaacc gggactggaa caatgacagt 29640
ggagagccca ggactcgtaa ccatggatca tcatgctcgt catgatatca atgttggcac 29700
aacacaggca cacgtgcata cacttcctca ggattacaag ctcctcccgc gttagaacca 29760
tatcccaggg aacaacccat tcctgaatca gcgtaaatcc cacactgcag ggaagacctc 29820
gcacgtaact cacgttgtgc attgtcaaag tgttacattc gggcagcagc ggatgatcct 29880
ccagtatggt agcgcgggtt tctgtctcaa aaggaggtag acgatcccta ctgtacggag 29940
tgcgccgaga caaccgagat cgtgttggtc gtagtgtcat gccaaatgga acgccggacg 30000
tagtcattga aatggattct cttgcgtacc ttgtcgtact tctgccagca gaaagtggct 30060
cgggaacagc agataccttt cctcctgctg tccttccgct gctgacgctc agtcatccaa 30120
ctgaagtaca gccattcccg caggttctcc agcagctcct gtgcatctga tgaaacaaaa 30180
gtcccgtcga tgcggattcc ccttaaaaca tcagccagga cattgtaggc catcccaatc 30240
cagttaatgc atcctgatct atcatgaaga ggaggtgggg gaagaactgg aagaaccatt 30300
tttattccaa gcggtctcga aggacgataa agtgcaagtc acgcaggtga cagcgttccc 30360
cgccgctgtg ctggtggaaa cagacagcca ggtcaaaacc cactctattt tcaaggtgct 30420
cgactgtggc ttcgagcagt ggctctacgc gtacatccag cataagaatc acattaaagg 30480
ctggacctcc atcgatttca tcaatcatca ggttacactc attcaccatc cccaggtaat 30540
tctcattttt ccagccttgg attatttcta caaattgttg gtgtaagtcc actccgcaca 30600
tgtggaaaag ttcccacagc gccccctcca ctttcataat caggcagacc ttcatattag 30660
aaacagatcc tgctgctcca ccacctgcag cgtgttcaaa acaacaagat tcaatgaggt 30720
tctgccctct gccctcagct cacgtctcag cgtcagctgc aaaaagtcac tcaagtcctc 30780
agccactaca gctgacaatt cagagccagg gctaagcgtg ggactggcaa gcgtgagtga 30840
gtactttaat gctccaaagc tagcacccaa aaactgcatg ctggaataag ctctctttgt 30900
gtcaccggtg atgccttcca ataggtgagt gataaagcga ggtagttttt ctttaatcat 30960
ttgagtaata gaaaagtcct ctaaataagt cactaggacc ccaggaacca caatgtggta 31020
gctgacagcg tgtcgctcaa gcatggttag tagagatgag agtctgaaaa acagaaagca 31080
tgcactaaac cagagttgcc agtctcactg aaggaaaaat cactctctcc agcagcaaag 31140
tgcccactgg gtggccctct cggacataca aaaatcgatc cgtgtggtta aagagcagca 31200
cagttagctc ctgtcttctc ccagcaaaga tcacatcgga ctgggttagt atgcccctgg 31260
aatggtagtc attcaaggcc ataaatctgc cttggtagcc attaggaatc agcacgctca 31320
ctctcaagtg aaccaaaacc accccatgcg gaggaatgtg gaaagattct gggcaaaaaa 31380
aggtatatct attgctagtc ccttcctgga cgggagcaat ccctccaggg ctatctatga 31440
aagcatacag agattcagcc atagctcagc ccgcttacca gtagacagag agcacagcag 31500
tacaagcgcc aacagcagcg actgactacc cactgaccca gctccctatt taaaggcacc 31560
ttacactgac gtaatgacca aaggtctaaa aaccccgcca aaaaaacaca cacgccctgg 31620
gtgtttttcg cgaaaacact tccgcgttct cacttcctcg tatcgatttc gtgactcaac 31680
ttccgggttc ccacgttacg tcacttctgc ccttacatgt aactcagccg tagggcgcca 31740
tcttgcccac gtccaaaatg gcttccatgt ccggccacgc ctccgcggcg accgttagcc 31800
gtgcgtcgtg acgtcatttg catcaccgtt tctcgtccaa tcagcgttgg ctccgcccca 31860
aaaccgttaa aattcaaaag ctcatttgca tattaacttt tgtttacttt gtggggtata 31920
ttattgatga tg 31932
<210> 11
<211> 31974
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr13.RSVF-2A-GLuc
<400> 11
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gactagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ttggccgtgc tcttcctgac gggtaggtgt 1320
cccctaacct agggagccaa ccatcggggg gccttctccc taaatccccg tggcccaccc 1380
tcctgggcag aggcagcagg tttctcactg gccccctctc ccccacctcc aagcttggcc 1440
tttcggctca gatctcagcc cacagctggc ctgatctggg tctcccctcc caccctcagg 1500
gagccaggct cggcatttcg tcgacatgga actgctgatc ctgaaggcca acgccatcac 1560
caccatcctg accgccgtga ccttctgctt cgccagcggc cagaacatca ccgaggaatt 1620
ctaccagagc acctgtagcg ccgtgtccaa gggctacctg agcgccctgc ggaccggctg 1680
gtacaccagc gtgatcacca tcgagctgag caacatcaaa aagaacaagt gcaacggcac 1740
cgacgccaaa atcaagctga tcaagcagga actggacaag tacaagaacg ccgtgaccga 1800
gctgcagctg ctgatgcaga gcacccccgc caccaacaac cgggccagac gggagctgcc 1860
ccggttcatg aactacaccc tgaacaacgc caaaaagacc aacgtgaccc tgagcaagaa 1920
gcggaagcgg cggttcctgg gcttcctgct gggcgtgggc agcgccattg ctagcggagt 1980
ggctgtgtct aaggtgctgc acctggaagg cgaagtgaac aagatcaagt ccgccctgct 2040
gagcaccaac aaggccgtgg tgtccctgag caacggcgtg tccgtgctga ccagcaaggt 2100
gctggatctg aagaactaca tcgacaagca gctgctgccc atcgtgaaca agcagagctg 2160
cagcatcagc aacatcgaga cagtgatcga gttccagcag aagaacaacc ggctgctgga 2220
aatcacccgc gagttcagcg tgaacgccgg cgtgaccacc cccgtgtcca cctacatgct 2280
gaccaacagc gagctgctga gcctgatcaa cgacatgccc atcaccaacg accagaaaaa 2340
gctgatgagc aacaacgtgc agatcgtgcg gcagcagagc tactccatca tgtccatcat 2400
caaagaagag gtgctggcct acgtggtgca gctgcccctg tacggcgtga tcgacacccc 2460
ctgctggaag ctgcacacca gccccctgtg caccaccaac accaaagagg gcagcaacat 2520
ctgcctgacc cggaccgacc ggggctggta ctgcgataat gccggcagcg tgtcattctt 2580
tccacaagcc gagacatgca aggtgcagag caaccgggtg ttctgcgaca ccatgaacag 2640
cctgaccctg cccagcgagg tgaacctgtg caacgtggac atcttcaacc ctaagtacga 2700
ctgcaagatc atgacctcca agaccgacgt gtccagctcc gtgatcacct ccctgggcgc 2760
catcgtgtcc tgctacggca agaccaagtg caccgccagc aacaagaacc ggggcatcat 2820
caagaccttc agcaacggct gcgactacgt gtccaacaag ggcgtggaca ccgtgtccgt 2880
gggcaacacc ctgtactacg tgaacaaaca ggaaggcaag agcctgtacg tgaagggcga 2940
gcccatcatc aacttctacg accccctggt gttccccagc gacgagttcg acgccagcat 3000
cagccaggtc aacgagaaga tcaaccagag cctggccttc atcagaaaga gcgacgagct 3060
gctgcacaat gtgaatgccg tgaagtccac caccaatatc atgatcacca caatcatcat 3120
cgtgatcatc gtcatcctgc tgtccctgat cgccgtgggc ctgctgctgt actgcaaggc 3180
ccggtccacc cctgtgaccc tgtccaagga ccagctgagc ggcatcaaca atatcgcctt 3240
ctccaacgga cgcgtgaccg agctgcttta ccggatgaag cgggctgaga catattgccc 3300
gagacccctg ttggcaatcc atcctactga ggctcgccac aaacagaaaa tcgtggcccc 3360
cgtcaaacag acactcaatt ttgacttgtt gaaacttgca ggagatgttg agtcaaaccc 3420
cgggcctatg ggcgtcaagg tcctgttcgc tctgatttgt atcgctgtcg ctgaagctaa 3480
gccaaccgag aataatgaag actttaatat cgtggccgtg gcttctaact tcgctaccac 3540
agacctggat gcagacaggg gaaagctgcc aggcaagaaa ctgcccctgg aggtcctgaa 3600
ggagatggaa gcaaatgccc ggaaagccgg gtgcacaaga ggatgcctga tttgtctgag 3660
ccacatcaag tgcactccta agatgaagaa gttcatcccc ggccggtgcc atacctacga 3720
gggcgataag gaatccgccc agggaggaat cggagaggct atcgtggata ttcccgaaat 3780
ccctggcttc aaagacctgg agcccatgga acagtttatt gcacaggtgg atctgtgcgt 3840
cgactgtact accggatgcc tgaagggact ggcaaacgtc cagtgtagcg acctgctgaa 3900
gaaatggctg cctcagcgat gtgctacatt tgccagcaag attcagggcc aggtggacaa 3960
gattaaggga gcaggaggcg actgataatt ctagacgaga tccgaacttg tttattgcag 4020
cttataatgg ttacaaataa agcaatagca tcacaaattt cacaaataaa gcattttttt 4080
cactgcattc tagttgtggt ttgtccaaac tcatcaatgt atcttatcat gtctagatcc 4140
aggtaggttt gagtagtggg cgtggctaag gtgactataa aggcgggtgt cttacgaggg 4200
tctttttgct tttctgcaga catcatgaac gggactggcg gggccttcga aggggggctt 4260
tttagccctt atttgacaac ccgcctgccg ggatgggccg gagttcgtca gaatgtgatg 4320
ggatcgacgg tggatgggcg cccagtgctt ccagcaaatt cctcgaccat gacctacgcg 4380
accgtgggga actcgtcgct cgacagcacc gccgcagccg cggcagccgc agccgccatg 4440
acagcgacga gactggcctc gagctacatg cccagcagcg gtagtagccc ctctgtgccc 4500
agttccatca tcgccgagga gaaactgctg gccctgctgg ccgagctgga agccctgagc 4560
cgccagctgg ccgccctgac ccagcaggtg tccgagctcc gcgaacagca gcagcagcaa 4620
aataaatgat tcaataaaca cagattctga ttcaaacagc aaagcatctt tattatttat 4680
tttttcgcgc gcggtaggcc ctggtccacc tctcccgatc attgagagtg cggtggattt 4740
tttccaggac ccggtagagg tgggattgga tgttgaggta catgggcatg agcccgtccc 4800
gtgggtggag gtagcaccac tgcatggcct cgtgctctgg ggtcgtgttg tagatgatcc 4860
agtcatagca ggggcgctgg gcgtggtgct ggatgatgtc cttgaggagg agactgatgg 4920
ccacggggag ccccttggtg taggtgttgg caaaacggtt gagctgggag ggatgcatgc 4980
ggggggagat gatgtgcagt ttggcctgga tcttgaggtt ggcgatgttg ccacccagat 5040
cccgccgggg gttcatgttg tgcaggacca ccagaacggt gtagcccgtg cacttgggga 5100
acttgtcatg caacttggaa gggaatgcgt ggaagaattt ggagacgccc ttgtgcccgc 5160
ccaggttttc catgcactca tccatgatga tggcaatggg cccgtgggct gcggctttgg 5220
caaagacgtt tctggggtca gagacatcgt aattatgctc ctgggtgaga tcatcataag 5280
acattttaat gaatttgggg cggagggtgc cagattgggg gacgatggtt ccctcgggcc 5340
ccggggcgaa gttcccctcg cagatctgca tctcccaggc tttcatctcg gaggggggga 5400
tcatgtccac ctgcggggcg atgaaaaaaa cggtttccgg ggcgggggtg atgagctgcg 5460
aggagagcag gtttctcaac agctgggact tgccgcaccc ggtcgggccg tagatgaccc 5520
cgatgacggg ttgcaggtgg tagttcaagg acatgcagct gccgtcgtcc cggaggaggg 5580
gggccacctc gttgagcttg tctctgactt ggaggttttc ccggacgagc tcgccgagga 5640
ggcggtcccc gcccagcgag agaagctctt gcagggaagc aaagtttttc aggggcttga 5700
gcccgtcggc catgggcatc ttggcgaggg tctgcgagag gagctccagg cggtcccaga 5760
gctcggtgac gtgctctacg gcatctcgat ccagcagact tcctcgtttc gggggttggg 5820
acgactgcga ctgtagggca cgagacgatg ggcgtccagc gcggccagcg tcatgtcctt 5880
ccagggtctc agggtccgcg tgagggtggt ctccgtcacg gtgaaggggt gggccgcggg 5940
ctgggcgctt gcaagggtgc gcttgagact catcctgctg gtgctgaaac gggcacggtc 6000
ttcgccctgc gcgtcggcga gatagcagtt gaccatgagc tcgtagttga gggcctcggc 6060
ggcgtggccc ttggcgcgga gcttgccctt ggaagagcgc ccgcaggcgg gacagaggag 6120
ggattgcagg gcgtagagct tgggcgcgag aaagacggac tcgggggcga aggcgtccgc 6180
tccgcagtgg gcgcagacgg tctcgcactc gactagccag gtgagctcgg gctgctcggg 6240
gtcaaaaacc agttttcccc cgttcttttt gatgcgcttc ttacctcgcg tctccatgag 6300
tctgtgtccg cgctcggtga caaacaggct gtctgtgtcc ccgtagacgg acttgatggg 6360
cctgtcctgc aggggcgtcc cgcggtcctc ctcgtagaga aactcagacc actctgagac 6420
gaaggcgcgc gtccacgcca agacaaagga ggccacgtgc gaggggtagc ggtcgttgtc 6480
caccaggggg tccacctttt ccacggtatg caggcacatg tccccctcct ccgcatccaa 6540
gaaggtgatt ggcttgtagg tgtaggccac gtgacctggg gttcccgacg ggggggtata 6600
aaagggggcg ggtctgtgct cgtcctcact ctcttccgcg tcgctgtcca cgagcgccag 6660
ctgttggggt aggtattccc tctcaagagc gggcatgacc tcggcactca ggttgtcagt 6720
ttctagaaac gaggaggatt tgatgtgggc ctgccctgcc gcgatgcttt ttaggagact 6780
ttcatccatc tggtcagaaa agactatttt tttattgtca agcttggtgg cgaaggagcc 6840
atagagggcg tttgagagaa gcttggcgat ggatctcatg gtctgatttt tgtcacggtc 6900
ggcgcgctcc ttggccgcga tgttgagctg gacatattcg cgcgcgacac acttccattc 6960
ggggaagacg gtggtgcgct cgtcgggcac gatcctgacg cgccagccgc ggttatgcag 7020
ggtgaccagg tccacgctgg tggccacctc gccgcgcagg ggctcgttgg tccagcagag 7080
tctgccgccc ttgcgcgagc agaacggggg cagcacatca agcagatgct cgtcaggggg 7140
gtccgcatcg atggtgaaga tgcccggaca gagttccttg tcaaaataat cgatttttga 7200
ggatgcatcg tccaaggcca tctgccactc gcgggcggcc agcgctcgct cgtaggggtt 7260
gaggggcgga ccccaaggca tgggatgcgt gagggcggag gcgtacatgc cgcagatgtc 7320
atagacatag atgggctccg agaggatgcc gatgtaggtg ggatagcagc gccccccgcg 7380
gatgcttgcg cgcacgtagt catacaactc gtgcgagggg gccaagaagg cggggccgag 7440
attggtgcgc tggggctgct cggcgcggaa gacgatctgg cgaaagatgg cgtgcgagtt 7500
ggaggagatg gtgggccgtt ggaagatgtt aaagtgggcg tgaggcaggc ggaccgagtc 7560
gcggatgaag tgcgcgtagg agtcttgcag cttggcgacg agctcggcgg tgacgaggac 7620
gtccatggcg cagtagtcca gcgtttcgcg gatgatgtca taactcgcct ctcctttctt 7680
ctcccacagc tcgcggttga gggcgtattc ctcgtcatcc ttccagtact cccggagcgg 7740
gaatcctcga tcgtccgcac ggtaagagcc cagcatgtag aaatggttca cggccttgta 7800
gggacagcag cccttctcca cggggagggc gtaagcttga gcggccttgc ggagcgaggt 7860
gtgcgtcagg gcaaaggtgt ccctgaccat gactttcaag aactggtact tgaagtccga 7920
gtcgtcgcag ccgccgtgct cccagagctc gaaatcggtg cgcttcttcg agagggggtt 7980
aggcagagcg aaagtgacgt cattgaagag aatcttgcct gcccgcggca tgaaattgcg 8040
ggtgatgcgg aaagggcccg ggacggaggc tcggttgttg atgacctggg cggcgaggac 8100
gatctcgtca aagccgttga tgttgtgccc gacgatgtag agttccatga atcgcgggcg 8160
gcctttgatg tgcggcagct ttttgagctc ctcgtaggtg aggtcctcgg ggcattgcag 8220
gccgtgctgc tcgagcgccc actcctggag atgtgggttg gcttgcatga aggaagccca 8280
gagctcgcgg gccatgaggg tctggagctc gtcgcgaaag aggcggaact gctggcccac 8340
ggccatcttt tctggggtga cgcagtagaa ggtgaggggg tcccgctccc agcgatccca 8400
gcgtaaacgc acggcgagat cgcgagcgag ggcgaccagc tctgggtccc cggagaattt 8460
catgaccagc atgaagggga cgagctgctt gccgaaggac cccatccagg tgtaggtttc 8520
tacatcgtag gtgacaaaga gccgctccgt gcgaggatga gagccgattg ggaagaactg 8580
gatttcctgc caccagttgg acgagtggct gttgatgtga tgaaagtaga aatcccgccg 8640
gcgaaccgag cactcgtgct gatgcttgta aaagcgtccg cagtactcgc agcgctgcac 8700
gggctgtacc tcatccacga gatacacagc gcgtcccttg aggaggaact tcaggagtgg 8760
cggccctggc tggtggtttt catgttcgcc tgcgtgggac tcaccctggg gctcctcgag 8820
gacggagagg ctgacgagcc cgcgcgggag ccaggtccag atctcggcgc ggcgggggcg 8880
gagagcgaag acgagggcgc gcagttggga gctgtccatg gtgtcgcgga gatccaggtc 8940
cgggggcagg gttctgaggt tgacctcgta gaggcgggtg agggcgtgct tgagatgcag 9000
atggtacttg atttctacgg gtgagttggt ggtcgtgtcc acgcattgca tgagcccgta 9060
gctgcgcggg gccacgaccg tgccgcggtg cgcttttaga agcggtgtcg cggacgcgct 9120
cccggcggca gcggcggttc cggccccgcg ggcaggggcg gcagaggcac gtcggcgtgg 9180
cgctcgggca ggtcccggtg ctgcgccctg agagcgctgg cgtgcgcgac gacgcggcgg 9240
ttgacatcct ggatctgccg cctctgcgtg aagaccacgg gccccgtgac tttgaacctg 9300
aaagacagtt caacagaatc aatctctgcg tcattgacgg cggcctgacg caggatctct 9360
tgcacgtcgc ccgagttgtc ctggtaggcg atctcggaca tgaactgttc gatctcctcc 9420
tcctggagat cgccgcggcc cgcgcgctcc acggtggcgg cgaggtcatt ggagatgcga 9480
cccatgagct gcgagaaggc gcccaggccg ctctcgttcc agacgcggct gtagaccacg 9540
tccccgtcgg cgtcgcgcgc gcgcatgacc acctgcgcga ggttgagctc cacgtgccgc 9600
gcaaagacgg cgtagttgcg caggcgctgg aagaggtagt tgagggtggt ggcgatgtgc 9660
tcggtgacga agaagtacat gatccagcgg cgcaggggca tctcgctgat gtcgccgatg 9720
gcttccagcc tttccatggc ctcgtagaag tccacggcga agttgaaaaa ctgggcgttg 9780
cgggccgaga ccgtgagctc gtcttccagg agccggatga gttcggcgat ggtggcgcgc 9840
acctcgcgct cgaaatcccc gggggcctcc tcctcttcct cttcttccat gacgacctct 9900
tcttctattt cttcctctgg gggcggtggt ggtggcgggg gccgacgacg acggcgacgc 9960
accgggagac ggtcgacgaa gcgctcgatc atctccccgc ggcggcgacg catggtttcg 10020
gtgacggcgc gaccccgttc gcgaggacgc agcgtgaaga cgccgccggt catctcccgg 10080
taatggggcg ggtccccatt gggcagcgat agggcgctga cgatgcatct tatcaattgc 10140
ggtgtagggg acgtgagcgc gtcgagatcg accggatcgg agaatctttc gaggaaagcg 10200
tctagccaat cgcagtcgca aggtaagctc aaacacgtag cagccctgcg gacgctgtta 10260
gaattgcggt tgctgatgat gtaattgaag taggcgtttt tgaggcggcg gatggtggcg 10320
aggaggacca ggtccttggg tccagcttgc tggatgcgga gccgctcggc catgccccag 10380
gcctggccct gacaccggct caggttcttg tagtagtcat gcatgagcct ctcaatgtca 10440
tcactggctg aggcggagtc ttccatgcgg gtgaccccga cgcccctgag cggctgcacg 10500
agcgccaggt cggcgacgac gcgctcggcg aggatggcct gttgcacgcg ggtgagggtg 10560
tcctggaagt cgtccatgtc gacgaagcgg tgataggccc cggtgttgat ggtgtaggtg 10620
cagttggcca tgagcgacca gttgacggtc tgcaggcctg gctgcacgac ctcggagtac 10680
ctgagccgcg agaaggcgcg cgagtcgaag acgtagtcgt tgcaggtgcg cacgaggtac 10740
tggtatccga ctaggaagtg cggcggcggc tggcggtaga gcggccagcg ctgggtggcc 10800
ggcgcgcccg gggccaggtc ctcgagcatg aggcggtggt agccgtagag gtagcgggac 10860
atccaggtga tgccggcggc ggtggtggag gcgcgcggga actcgcggac gcggttccag 10920
atgttgcgca gcggcaggaa atagtccatg gtcggcacgg tctggccggt gagacgcgcg 10980
cagtcattga cgctctagag gcaaaaacga aagcggttga gcgggctctt cctccgtagc 11040
ctggcggaac gcaaacgggt taggccgcgt gtgtaccccg gttcgagtcc cctcgaatca 11100
ggctggagcc gcgactaacg tggtattggc actcccgtct cgacccgagc ccgatagccg 11160
ccaggatacg gcggagagcc ctttttgccg gccgagtggg gtcgctagac ttgaaagcga 11220
ccgaaaaccc tgccgggtag tggctcgcgc ccgtagtctg gagaagcatc gccagggttg 11280
agtcgcggca gaacccggtt cgaggacggc cgcggcgagc gggacttggt caccccgccg 11340
atataaagac ccacagccag ccgacttctc cagttacggg agcgagcccc cttttttctt 11400
tttgccagat gcatcccgtc ctgcgccaaa tgcgtcccac ccccccggcg accaccgcga 11460
ccgcggccgt agcaggcgcc ggcgctagcc agccaccaca gacagagatg gacttggaag 11520
agggcgaagg gctggcaaga ctgggggcgc cgtccccgga gcgacatccc cgcgtgcagc 11580
tgcagaagga cgtgcgcccg gcgtacgtgc ctacgcagaa cctgttcagg gaccgcagcg 11640
gggaggagcc cgaggagatg cgcgactgcc ggtttcgggc gggcagggag ctgcgcgagg 11700
gcctggaccg ccagcgcgtg ctgcgcgacg aggatttcga gccgaacgag cagacgggga 11760
tcagccccgc acgcgcgcac gtggcggcag ccaacctggt gacggcctac gagcagacgg 11820
tgaagcagga gcgcaacttc caaaagagtt tcaacaacca cgtgcgcacc ctgatcgcgc 11880
gcgaggaggt ggccctgggc ctgatgcacc tgtgggacct ggcggaggcc atcgtgcaga 11940
acccggacag caagcctctg acggcgcagc tgttcctggt ggtgcagcac agcagggaca 12000
acgaggcgtt cagggaggcg ctgctgaaca tcgccgagcc cgagggtcgc tggctgctgg 12060
agctgattaa catcttgcag agcatcgtag tgcaggagcg cagcctgagc ctggccgaga 12120
aggtggcggc gatcaactac tcggtgctga gcctgggcaa gttttacgcg cgcaagattt 12180
acaagacgcc gtacgtgccc atagacaagg aggtgaagat agacagcttt tacatgcgca 12240
tggcgctcaa ggtgctgacg ctgagcgacg acctgggcgt gtaccgcaac gaccgcatcc 12300
acaaggccgt gagcacgagc cggcggcgcg agctgagcga ccgcgagctg atgctgagtc 12360
tgcgccgggc gctggtaggg ggcgccgccg gcggcgagga gtcctacttc gacatgggtg 12420
cggacctgca ttggcagccg agccggcgcg ccttggaggc cgcctacggt tcagaggact 12480
tggatgagga agaggaagag gaggaggatg cacccgctgc ggggtactga cgcctccgtg 12540
atgtgttttt agatgtccca gcaagccccg gaccccgcca taagggcggc gctgcaaagc 12600
cagccgtccg gtctagcatc ggacgactgg gaggccgcga tgcaacgcat catggccctg 12660
acgacccgca accccgagtc ctttagacaa cagccgcagg ccaacagact ctcggccatt 12720
ctggaggcgg tggtcccctc tcggaccaac cccacgcacg agaaggtgct ggcgatcgtg 12780
aacgcgctgg cggagaacaa ggccatccgt cccgacgagg ccgggctggt gtacaacgcc 12840
ctgctggagc gcgtgggccg ctacaacagc acgaacgtgc agtccaacct ggatcggctg 12900
gtgacggacg tgcgcgaggc cgtggcgcag cgcgagcggt tcaagaacga gggcctgggc 12960
tcgctggtgg cgctgaacgc cttcctggcg acgcagccgg cgaacgtgcc gcgcgggcag 13020
gacgattaca ccaactttat cagcgcgctg cggctgatgg tgaccgaggt gccccagagc 13080
gaggtgtacc agtctggccc ggactacttt ttccagacga gccggcaggg cttgcagacg 13140
gtgaacctga gccaggcttt caagaatctg cgcgggctgt ggggcgtgca ggcgcccgtg 13200
ggcgaccggt caacggtgag cagcttgctg acgcccaact cgcggctgct gctgctgctg 13260
atcgcgccct tcaccgacag cggcagcgtg aaccgcaact cgtacctggg ccatctgctg 13320
acgctgtacc gcgaggccat aggccaggcg caggtggacg agcagacctt ccaggagatc 13380
actagcgtga gccgcgcgct ggggcagaac gacaccgaca gtctgagggc caccctgaac 13440
tttttgctga ccaatagaca gcagaagatc ccggcgcagt acgcactgtc ggccgaggag 13500
gaaaggattc tgagatatgt gcagcagagc gtagggctgt tcctgatgca ggagggtgcc 13560
acccccagcg ccgcgctgga catgaccgcg cgcaacatgg aacctagcat gtacgccgcc 13620
aaccggccgt tcatcaataa gctgatggac tacttgcacc gcgcggcggc catgaacacg 13680
gactacttta ccaacgccat cctgaacccg cactggctcc cgccgccggg gttctacacg 13740
ggcgagtacg acatgcccga ccccaacgac gggttcctgt gggacgacgt ggacagcgcg 13800
gtgttctcgc cgacctttca aaagcgccag gaggcgccgc cgagcgaggg cgcggtgggg 13860
aggagcccct ttcctagctt agggagtttg catagcttgc cgggctcggt gaacagcggc 13920
agggtgagcc ggccgcgctt gctgggcgag gacgagtacc tgaacgactc gctgctgcag 13980
ccgccgcggg ccaagaacgc catggccaat aacgggatag agagtctggt ggacaaactg 14040
aaccgctgga agacctacgc tcaggaccat agggacgcgc ccgcgccgcg gcgacagcgc 14100
cacgaccggc agcggggcct ggtgtgggac gacgaggact cggccgacga tagcagcgtg 14160
ttggacttgg gcgggagcgg tggggtcaac ccgttcgcgc atctgcagcc caaactgggg 14220
cgacggatgt tttgaatgaa ataaaactca ccaaggccat agcgtgcgtt ctcttccttg 14280
ttagagatga ggcgcgcggt ggtgtcttcc tctcctcctc cctcgtacga gagcgtgatg 14340
gcgcaggcga ccctggaggt tccgtttgtg cctccgcggt atatggctcc tacggagggc 14400
agaaacagca ttcgttactc ggagctggct ccgcagtacg acaccactcg cgtgtacttg 14460
gtggacaaca agtcggcgga catcgcttcc ctgaactacc aaaacgacca cagcaacttc 14520
ctgaccacgg tggtgcagaa caacgatttc acccccgccg aggccagcac gcagacgata 14580
aattttgacg agcggtcgcg gtggggcggt gatctgaaga ccattctgca cactaacatg 14640
cccaatgtga acgagtacat gttcaccagc aagtttaagg cgcgggtgat ggtgtctagg 14700
aagcatccag agggggtagt tgaaacagat ttgagtcagg ataagcttga atatgagtgg 14760
tttgagttta ccctgcccga gggaaacttt tccgagacca tgaccataga cctgatgaac 14820
aacgccatct tggaaaacta cttgcaagtg gggcggcaga atggcgtgct ggagagcgat 14880
atcggagtca agtttgacag cagaaatttc aagctgggct gggacccggt gaccaagctg 14940
gtgatgccag gggtctacac ctacgaggcc ttccacccgg acgtggtgct gctgccgggc 15000
tgcggggtgg acttcaccga gagccgcctg agcaacctcc tgggcattcg caagaagcaa 15060
cctttccaag agggcttcag aatcatgtat gaggatctag aaggtggcaa catccccgcc 15120
ctccttgatg tgcccaagta cttggaaagc aagaagaaag ttgaagacga aactaaaaat 15180
gcagctgcgg ccacagccga tacaaccact aggggtgata catttgcaac tccagcgcaa 15240
gagacagcag ctgataagaa ggtagaagtc ttgcccattg aaaaggatga gagtggtaga 15300
agttacaacc tgatccaggg gacccacgac acgctgtacc gcagttggta cctgtcctat 15360
acctacgggg accccgagaa gggggtgcag tcgtggacgc tgctcaccac cccggacgtt 15420
acctgcggcg cggagcaagt ctactggtca ctgccggacc tcatgcaaga ccccgtcacc 15480
ttccgctcca cccagcaagt cagcaactac cccgtggtcg gcgccgagct catgcccttc 15540
cgcgccaaga gcttttacaa cgacctcgcc gtctactccc agctcatccg cagctacacc 15600
tccctcaccc acgtcttcaa ccgcttcccc gacaaccaga tcctctgccg cccgcccgcg 15660
cccaccatca ccaccgtcag tgaaaacgtg cctgctctca cagatcacgg gacgctaccg 15720
ctgcgcagca gtatccgcgg agtccagcga gtgaccgtca ctgacgcccg tcgccgcacc 15780
tgtccctacg tctacaaggc cctgggcata gtcgcgccgc gcgtgctttc cagtcgcacc 15840
ttctaaaaaa atgtctattc tcatctcgcc cagcaataac accggctggg gtcttactag 15900
acccagcacc atgtacggag gagccaagaa gcgctcccag cagcaccccg tccgcgtccg 15960
cggccacttc cgcgctccct ggggcgcata caagcgcggg cggacttcca ccgccgccgt 16020
gcgcaccacc gtcgacgacg tcatcgactc ggtggtcgcc gacgcgcgca actatacccc 16080
cgccccctcc accgtggacg cggtcatcga cagcgtggtg gccgacgcgc gcgactatgc 16140
cagacgcaag agccggcggc gacggatcgc caggcgccac cggagcacgc ccgccatgcg 16200
cgccgcccgg gctctgctgc gccgcgccag acgcacgggc cgccgggcca tgatgcgagc 16260
cgcgcgccgc gctgccactg cacccacccc cgcaggcagg actcgcagac gagcggccgc 16320
cgccgccgct gcggccatct ctagcatgac cagacccagg cgcggaaacg tgtactgggt 16380
gcgcgactcc gtcacgggcg tgcgcgtgcc cgtgcgcacc cgtcctcctc gtccctgatc 16440
taatgcttgt gtcctccccc gcaagcgacg atgtcaaagc gcaaaatcaa ggaggagatg 16500
ctccaggtcg tcgccccgga gatttacgga ccaccccagg cggaccagaa accccgcaaa 16560
atcaagcggg ttaaaaaaaa ggatgaggtg gacgaggggg cagtagagtt tgtgcgcgag 16620
ttcgctccgc ggcggcgcgt aaattggaag gggcgcaggg tgcagcgcgt gttgcggccc 16680
ggcacggcgg tggtgttcac gcccggcgag cggtcctcgg tcaggagcaa gcgtagctat 16740
gacgaggtgt acggcgacga cgacatcctg gaccaggcgg cggagcgggc gggcgagttc 16800
gcctacggga agcggtcgcg cgaagaggag ctgatctcgc tgccgctgga cgaaagcaac 16860
cccacgccga gcctgaagcc cgtgaccctg cagcaggtgc tgccccaggc ggtgctgctg 16920
ccgagccgcg gggtcaagcg cgagggcgag agcatgtacc cgaccatgca gatcatggtg 16980
cccaagcgcc ggcgcgtgga ggacgtgctg gacaccgtga aaatggatgt ggagcccgag 17040
gtcaaggtgc gccccatcaa gcaggtggcg ccgggcctgg gcgtgcaaac cgtggacatt 17100
cagatcccca ccgacatgga tgtcgacaaa aaaccctcga ccagcatcga ggtgcaaacc 17160
gacccctggc tcccagcctc caccgctacc gtctccactt ctaccgccgc cacggctacc 17220
gagcctccca ggaggcgaag atggggcgcc gccagccggc tgatgcccaa ctacgtgttg 17280
catccttcca tcatcccgac gccgggctac cgcggcaccc ggtactacgc cagccgccgg 17340
cgcccagcca gcaaacgccg ccgccgcacc gccacccgcc gccgtctggc ccccgcccgc 17400
gtgcgccgcg tgaccacgcg ccggggccgc tcgctcgttc tgcccaccgt gcgctaccac 17460
cccagcatcc tttaatccgt gtgctgtgat actgttgcag agagatggct ctcacttgcc 17520
gcctgcgcat ccccgtcccg aattaccgag gaagatcccg ccgcaggaga ggcatggcag 17580
gcagcggcct gaaccgccgc cggcggcggg ccatgcgcag gcgcctgagt ggcggctttc 17640
tgcccgcgct catccccata atcgccgcgg ccattggcac gatcccgggc atagcttccg 17700
ttgcgctgca ggcgtcgcag cgccgttgat gtgcgaataa agcctcttta gactctgaca 17760
cacctggtcc tgtatatttt tagaatggaa gacatcaatt ttgcgtccct ggctccgcgg 17820
cacggcacgc ggccgttcat gggcacctgg aacgagatcg gcaccagcca gctgaacggg 17880
ggcgccttca attggagcag tgtctggagc gggcttaaaa atttcggctc gacgctccgg 17940
acctatggga acaaggcctg gaatagtagc acggggcagt tgttgaggga aaagctcaaa 18000
gaccagaact tccagcagaa ggtggtggac gggctggcct cgggcattaa cggggtggtg 18060
gacatcgcga accaggccgt gcagcgcgag ataaacagcc gcctggaccc gcgaccgccc 18120
acggtggtgg agatggaaga tgcaactctt ccgccgccca agggcgagaa gcggccgcgg 18180
cccgacgcgg aggagacgat cctgcaggtg gacgagccgc cctcgtacga ggaggccgtc 18240
aaggccggca tgcccaccac gcgcatcatc gcgccgctgg ccacgggtgt aatgaaaccc 18300
gccacccttg acctgcctcc accacccgcg cccgctccac cgaaggcaac tccggttgtg 18360
caggcccccc cggtggcgac cgccgtgcgc cgcgtccccg cccgccgcca ggcccagaac 18420
tggcagagca cgctgcacag tatcgtgggc ctgggagtga aaagtctgaa gcgccgccga 18480
tgctattgag agagaggaaa gaggacacta aagggagagc ttaacttgta tgtgccttac 18540
cgccagagaa cgcgcgaaga tggccacccc ctcgatgatg ccgcagtggg cgtacatgca 18600
catcgccggg caggacgcct cggagtacct gagcccgggt ctggtgcagt ttgcccgcgc 18660
caccgacacg tacttcagcc tgggcaacaa gtttaggaac cccacggtgg ccccgaccca 18720
cgatgtgacc acggaccggt cccagcgtct gacgctgcgc ttcgtgcccg tggatcgcga 18780
ggacaccacg tactcgtaca aggcgcgctt cactctggcc gtgggcgaca accgggtgct 18840
agacatggcc agcacttact ttgacatccg cggcgtcctg gaccgcggtc ccagcttcaa 18900
accctactcg ggcacggcct acaacagcct ggctcccaag ggtgccccca attccagcca 18960
gtgggagcaa gcaaaaccag gcaatggggg aactatggaa acacacacat atggtgtggc 19020
cccaatgggc ggagagaata ttacaaaaga tggtcttcaa attggaactg atgctacagc 19080
ggatcagaat aaaccaattt atgctgacaa aactttccag ccagaacctc aagtaggaga 19140
agaaaattgg caagaaactg aaagctttta tggtggtagg gctcttaaaa aagacactaa 19200
aatgaaacca tgctatggat cttttgctag acctactaat gagaaaggag gtcaggcaaa 19260
gttcaaacca gttaatgaag gagaacaacc taaagatctg gatatagatc tggctttctt 19320
tgatactccc ggtggcactg tgaatggcca agatgagtat aaagcagaca ttgtcatgta 19380
cactgaaaat gttaatcttg aaacaccaga cactcatgtg gtttacaagc caggcaagga 19440
agatgcaagt tctgaaatta acctggttca gcagtccatg ccaaacagac ccaactacat 19500
tggctttagg gacaactttg taggtctcat gtattacaac agcaccggaa atatgggtgt 19560
gctggctggt caggcttctc agttgaacgc tgtggtcgac ttgcaagaca gaaacaccga 19620
gttatcttac cagctattgc tagattctct gggtgacaga accagatact ttagcatgtg 19680
gaactctgcg gtggacagtt acgatccaga tgtcaggatc attgaaaatc acggtgtgga 19740
agatgaactt ccaaactatt gcttcccatt ggatggatct ggcactaacg ccgcctatca 19800
aggtgtaaaa gtaaaaaatg gtgaagatgg tgatcttgag agcgagtggg aaaatgatga 19860
tactgtggca gctcgaaatc aaatatgcaa aggcaatatt ttcgccatgg agatcaacct 19920
gcaggccaac ctgtggaaga gttttctgta ctcgaacgtg gccctgtacc tgcccgactc 19980
ctacaagtac acgccggcca acgtcaagct gcccgccaac accaacacct acgagtacat 20040
gaacggccgc gtggtagccc cctcgctggt ggacgcctac atcaacatcg gcgcccgctg 20100
gtcgttggat cccatggaca acgtcaaccc cttcaaccac caccgcaatg cgggcctgcg 20160
ctaccgctcc atgctgctgg gcaacggccg ctacgtgccc ttccacatcc aagtgcccca 20220
aaagttcttt gccatcaaga acctgctcct gctcccgggc tcctacacct acgagtggaa 20280
cttccgcaag gacgtcaaca tgatcctgca gagttccctc ggcaacgacc tgcgcgtcga 20340
cggcgcctcc gtccgcttcg acagcgtcaa cctatacgcc actttcttcc ccatggcgca 20400
caacaccgct tcaaccttgg aagccatgct gcgcaacgac accaacgacc agtccttcaa 20460
cgactacctc tcggccgcca acatgctcta ccccatcccg gccaaggcca ccaacgtgcc 20520
catctccatc ccatcgcgca actgggccgc cttccgcggc tggagtttca cccggctcaa 20580
gaccaaggaa actccttccc tcggctcggg tttcgacccc tactttgtct actcgggctc 20640
catcccctac ctcgacggga ccttctacct caaccacacc ttcaagaagg tctccatcat 20700
gttcgactcc tcggtcagct ggcccggcaa cgaccggctg ctcacgccga acgagttcga 20760
gatcaagcgc agcgtcgacg gggagggcta caacgtggcc caatgcaaca tgaccaagga 20820
ctggttcctc gtccagatgc tctcccacta caacatcggc taccagggct tccacgtgcc 20880
cgagggctac aaggaccgca tgtactcctt cttccgcaac ttccagccca tgagcaggca 20940
ggtggtcgat gagatcaact acaaggacta caaggccgtc accctgccct tccagcacaa 21000
taactcgggc ttcaccggct acctcgcacc caccatgcgc caggggcagc cctaccccgc 21060
caacttcccc tacccgctca tcggtcagac agccgtgccc tccgtcaccc agaaaaagtt 21120
cctctgcgac agggtcatgt ggcgcatccc cttctccagc aacttcatgt ccatgggcgc 21180
cctcaccgac ctgggtcaga acatgctcta cgccaactcg gcccacgcgc tcgacatgac 21240
cttcgaggtg gaccccatgg atgagcccac cctcctctat cttctcttcg aagttttcga 21300
cgtggtcaga gtacaccagc cgcaccgcgg cgtcatcgag gccgtctacc tgcgcacgcc 21360
cttctccgcc ggcaacgcca ccacctaagc atgagcggct ccagcgaacg agagctcgcg 21420
gccatcgtgc gcgacctggg ctgcgggccc tactttttgg gcacccacga caagcgcttc 21480
ccgggctttc tcgccggcga caagctggcc tgcgccatcg tcaacacggc cggccgcgag 21540
accggaggcg tgcactggct cgccttcggc tggaacccgc gctcgcgcac ctgctacatg 21600
ttcgacccct ttgggttctc ggaccgccgg ctcaagcaga tttacagctt cgagtacgag 21660
gccatgctgc gccgcagcgc cctggcctcc tcgcccgacc gctgtctcag cctcgagcag 21720
tccactcaga ccgtgcaggg gcccgactcc gccgcctgcg gactcttctg ttgcatgttc 21780
ttgcatgcct tcgtgcactg gcccgaccga cccatggacg gaaaccccac catgaacttg 21840
ctgacggggg tgcccaacgg catgctacaa tcgccacagg tgctgcccac cctcaggcgc 21900
aaccaggagg aactctaccg cttcctcgcg cgccactccc cttactttcg ctcccaccgc 21960
gccgccatcg aacacgccac cgcttttgac aaaatgaaac aactgcgtgt atctcaataa 22020
acagcacttt tattttacat gcactggagt atatgcaagt tatttaaaag tcgaaggggt 22080
tctcgcgctc gtcgttgtgc gccgcgctgg ggagggccac gttgcggtac tggtacttgg 22140
gctgccactt gaactcgggg atcaccagtt tgggcactgg ggtctcgggg aaggtctcgc 22200
tccacatgcg ccggctcatc tgcagggcgc ccagcatgtc cggggcggag atcttgaaat 22260
cgcagttggg gccggtgctc tgcgcgcgcg agttgcggta cacggggttg cagcactgga 22320
acaccatcag actggggtac ttcacactag ccagcacgct cttgtcgctg atctgatcct 22380
tgtccagatc ctcggcgttg ctcaggccga acggggtcat cttgcacagc tggcgtccca 22440
ggaagggcac gctctgaggc ttgtggttac actcgcagtg cacgggcatc agcatcatcc 22500
ccgcgccgcg ctgcatattc gggtagaggg ccttgacaaa ggccgcgatc tgcttgaaag 22560
cttgctgggc cttggccccc tcgctgaaaa acaggccgca gctcttcccg ctgaactggt 22620
tattcccaca cccggcatcc tgcacgcagc agcgcgcgtc atggctggtc agttgcacca 22680
cgctccgtcc ccagcggttc tgggtcacct tagccttgct gggctgctcc ttcaacgcgc 22740
gctgcccgtt ctcgctggtc acatccatct ccaccacgtg gtccttgtgg atcatcatcg 22800
tcccgtgcag acacttgagc tggccttcca cctcggtgca gccgtgatcc cacagggcgc 22860
aaccggtgca ctcccagttc ttgtgcgcaa tcccgctgtg gctgaagatg taaccttgca 22920
acatgcggcc catgatggtg ctaaatgctt tctgggtggt gaaggtcagt tgcatcccgc 22980
gggcctcctc gttcatccag gtctggcaca tcttctggaa gatctcggtc tgctcgggca 23040
tgagcttgta agcatcgcgc aggccgctgt cgacgcggta gcgttccatc agcacgttca 23100
tggtatccat gcccttctcc caggacgaga ccagaggcag actcagaggg ttgcgtacgt 23160
tcaggacacc gggggtcgcg ggctcgacga tgcgttttcc gtccttgcct tccttcaata 23220
gaaccggcgg ctggctgaat cccactccca cgatcacggc atcttcctgg ggcatctctt 23280
cgtcggggtc taccttggtc acatgcttgg tctttctggc ttgcttcttt tttggagggc 23340
tgtccacggg gagcacgtcc tcctcggaag acccggagcc cacccgctga tactttcggc 23400
gcttggtggg cagaggaggt ggcggcgagg ggctcctctc ctgctccggc ggatagcgcg 23460
ccgacccgtg gccccggggc ggagtggcct ctcggcccat gaaccggcgc acgtcctgac 23520
tgccgccggc cattgtttcc taggggaaga tggaggagca gccgcgtaag caggagcagg 23580
aggaggactt aaccacccac gagcaaccca aaatcgagca ggacctgggc ttcgaagagc 23640
cggctcgtct agaaccccca caggatgaac aggagcacga gcaagacgca ggccaggagg 23700
agaccgacgc tgggctcgag catggctacc tgggaggaga ggaggatgtg ctgctgaaac 23760
acctgcagcg ccagtccctc atcctccggg acgccctggc cgaccggagc gaaacccccc 23820
tcagcgtcga ggagctgtgt cgggcctacg agctcaacct cttctcgccg cgcgtacccc 23880
ccaaacgcca gcccaacggc acctgcgagc ccaacccgcg tctcaacttc tatcccgtct 23940
ttgcggtccc cgaagccctc gccacctatc acatcttttt caagaaccaa aagatccccg 24000
tctcctgccg cgccaaccgc accagcgccg acgcgctcct cgctttgggg cccggcgcgc 24060
gcatacctga tatcgcttcc ctggaagagg tgcccaagat cttcgaaggg ctcggtcggg 24120
acgagacgcg cgcggcgaac gctctgaaag aaacagcaga ggaagagggt cacactagcg 24180
ccctggtaga gttggaaggc gacaacgcca ggctggccgt gctcaagcgc agcgtcgagc 24240
ttacccactt cgcctacccc gccgtcaacc tcccgcccaa ggtcatgcgt cgcatcatgg 24300
atcagctcat catgccccac atcgaggccc tcgatgaaag tcaggagcag cgccccgagg 24360
acgcccggcc cgtggtcagc gacgagatgc tcgcgcgctg gctcgggacc cgcgaccccc 24420
aggctttgga acagcggcgc aaactcatgc tggccgtggt cctggtcacc cttgagctcg 24480
aatgcatgcg ccgctttttc agcgaccccg agaccctgcg caaggtcgag gagaccctgc 24540
actacacttt caggcacggt ttcgtcaggc aggcctgcaa gatctccaac gtggagctga 24600
ccaacctggt ctcctgcctg gggatcctgc acgagaaccg cctgggccag accgtgctcc 24660
actctaccct gaagggcgag gcgcggcggg actatgtccg cgactgcgtc tttctctttc 24720
tctgccacac atggcaagcg gccatgggcg tgtggcagca gtgtctcgag gacgagaacc 24780
taaaggagct ggacaagctt cttgctagaa accttaaaaa gctgtggacg ggcttcgacg 24840
agcgcaccgt cgcctcggac ctggccgaga tcgtcttccc cgagcgcctg agacagacgc 24900
tgaaaggcgg gctgcccgac ttcatgagcc agagcatgtt gcaaaactac cgcactttca 24960
ttcttgagcg atcaggcatc ctgcccgcca cctgcaacgc cttcccctcc gactttgtac 25020
cgctgagcta ccgcgagtgt cccccgccgc tgtggagcca ctgctacctc ttgcagctgg 25080
ccaactacat cgcctaccac tcggacgtga tcgaggacgt gagcggcgag gggctgctcg 25140
agtgccactg tcgctgcaac ctgtgctccc cgcatcgctc cctggtctgc aacccccagc 25200
tcctgagcga gacccaggtc atcggtacct tcgagctgca aggtccgcag gagtccaccg 25260
ctccgctgaa actcacgccg gggttgtgga cttccgcgta cctgcgcaaa tttgtacccg 25320
aagactacca cgcccatgag ataaagttct ttgaggacca atcgcgtccg cagcacgcgg 25380
atctcacggc ctgcgtcatc acccagggcg cgatcctcgc ccaattgcac gccatccaaa 25440
aatcccgcca agagtttctt ctgaaaaagg gtagaggggt ctacctggac ccccagacgg 25500
gcgaggtgct caacccgggt ctcccccagc atgccgagga agaagcagga gccgctagtg 25560
gaggagatgg aagaagaatg ggacagccag gcagaggagg acgaatggga ggaggagaca 25620
gaggaggaag aattggaaga ggtggaagag gagcaggcaa cagagcagcc cgtcgccgca 25680
ccatccgcgc cggcagcccc gccggtcacg gatacaacct ccgctccggt caagcctcct 25740
cgtagatggg atcaagtgaa gggtgacggt aagcacgagc ggcagggcta ccgatcatgg 25800
agggcccaca aagccgcgat catcgcctgc ttgcaagact gcggggggaa catcgctttc 25860
gcccgccgct acctgctctt ccaccgcggg gtgaacatcc cccgcaacgt gttgcattac 25920
taccgtcacc ttcacagcta agaaaaagca agtcaaagga gtcgccggag gaggaggagg 25980
aggcctgagg atcgcggcga acgagccctt gaccaccagg gagctgagga accggatctt 26040
ccccactctt tatgccattt ttcagcagag tcgaggtcag cagcaagagc tcaaagtaaa 26100
aaaccggtct ctgcgctcgc tcacccgcag ttgcttgtac cacaaaaacg aagatcagct 26160
gcagcgcact ctcgaagacg ccgaggctct gttccacaag tactgcgcgc tcactcttaa 26220
agactaaggc gcgcccaccc ggaaaaaagg cgggaattac ctcatcgcca ccatgagcaa 26280
ggagattccc accccttaca tgtggagcta tcagccccaa atgggcctgg ccgcgggcgc 26340
ctcccaggac tactccaccc gcatgaactg gctcagtgcc ggcccctcga tgatctcacg 26400
ggtcaacggg gtccgcagtc atcgaaacca gatattgttg gagcaggcgg cggtcacctc 26460
cacgcccagg gcaaagctca acccgcgtaa ttggccctcc accctggtgt atcaggaaat 26520
ccccgggccg actaccgtac tacttccgcg tgacgcactg gccgaagtcc gcatgactaa 26580
ctcaggtgtc cagctggccg gcggcgcttc ccggtgcccg ctccgcccac aatcgggtat 26640
aaaaaccctg gtgatccgag gcagaggcac acagctcaac gacgagttgg tgagctcttc 26700
gatcggtctg cgaccggacg gagtgttcca actagccgga gccgggagat cctccttcac 26760
tcccaaccag gcctacctga ccttgcagag cagctcttcg gagcctcgct ccggaggcat 26820
cggaaccctc cagtttgtgg aggagtttgt gccctcggtc tacttcaacc ccttctcggg 26880
atcgccaggc ctctacccgg acgagttcat accgaacttc gacgcagtga gagaagcggt 26940
ggacggctac gactgaatgt cccatggtga ctcggctgag ctcgctcggt tgaggcatct 27000
ggaccactgc cgccgcctgc gctgcttcgc ccgggagagc tgcggactca tctactttga 27060
gtttcccgag gagcacccca acggccctgc acacggagtg cggatcaccg tagagggcac 27120
caccgagtct cacctggtca ggttcttcac ccagcaaccc ttcctggtcg agcgggaccg 27180
gggcgccacc acctacaccg tctactgcat ctgtccaacc ccgaagttgc atgagaattt 27240
ttgttgtact ctttgtggtg agtttaataa aagctaaact cttgcaatac tctggacctt 27300
gtcgtcgtca actcaacgag accgtctacc tcaccaacca gactgaggta aaactcacct 27360
gcagaccaca caagacctat atcatctggt tcttcgagaa cacctcattt gcagtctcca 27420
acactcactg cactagtcca tgaactgatg ttgattaaaa gcccaaaaac caatcagccc 27480
cttcccccat ttccccatcc cccaattact cataaaaaat aaatcattgg aattaatcat 27540
tcaataaaga tcacttactt gaaatctgaa agtatgtctc tggtgtagtt gttcagcagc 27600
acctcggtac cctcctccca gctctggtac tccagtcccc ggcgggcggc gaacttcctc 27660
cacaccttga aagggatgtc aaattcctgg tccacaattt tcattgtctt ccctctcaga 27720
tggcaaagag gctccgggtg gaagatgact tcaaccccgt ctacccctat ggctacgcgc 27780
ggaatcagaa tatccccttc ctcactcccc cctttgtctc ctccgatgga ttcaaaaact 27840
tcccccctgg ggtcctgtca cttaaactgg ctgatccaat caccatcaac aatggggatg 27900
tctcacttaa ggtgggaggg ggacttgctg tagagcaaca gactggtaac ctaagcgtaa 27960
accctgatgc acccttgcaa gttgcaagtg ataagctaca gcttgctctg gctcctccat 28020
tcgaggtcag agatggaaag cttgctttaa aggcaggtaa tggattaaaa gtactagata 28080
attccattac tggattgact ggattattga atacacttgt ggtattaact ggaaggggaa 28140
taggaacgga ggaattaaaa aatgacgatg gtgtaacaaa caaaggagtc ggcttgcgtg 28200
taagacttgg agatgacggc gggctgacat ttgataaaaa gggtgattta gtagcctgga 28260
ataaaaaaga tgacaggcgc accctgtgga caacccctga cacatctcca aattgcaaaa 28320
tgagtacaga aaaggattct aaacttacgt tgacacttac aaagtgtgga agtcaggttc 28380
tgggaaatgt atctttactt gcagttacag gtgaatatca tcaaatgact gctactacaa 28440
agaaggatgt aaaaatatct ttactatttg atgagaatgg aattctatta ccatcttcgt 28500
cccttagcaa agattattgg aattacagaa gtgatgattc tattgtatct caaaaatata 28560
ataatgcagt tccattcatg ccaaacctga cagcttatcc aaaaccaagc gctcaaaatg 28620
caaaaaacta ttcaagaact aaaatcataa gtaatgtcta cttaggtgct cttacctacc 28680
aacctgtaat tatcactatt gcatttaatc aggaaactga aaatggatgt gcttattcta 28740
taacatttac cttcacttgg caaaaagact attctgccca acagtttgat gttacatctt 28800
ttaccttctc atatcttacc caagagaaca aagacaaaga ctaataaaat gttttgaact 28860
gaatttatga atctttattt atttttacac cagcacgggt agtcagtttc ccaccaccag 28920
cccatttcac agtgtaaaca gtcctttctc cccggctggc cttaaaaagc atcatatcat 28980
gggtaacaga catattctta ggtgttatat tccacacggt ttcctgtcga gccaaacgct 29040
catcagtgat attaataaac tccccgggca gctcacttaa gttcatgtcg ctgtccagct 29100
gctgagccac aggctgctgt ccaacttgcg gttgcttaac gggcggcgaa ggagaagtcc 29160
acgcctacat gggggtagag tcataatcgt gcatcaggat agggcggtgg tgctgcagca 29220
gcgcgcgaat aaactgctgc cgccgccgct ccgtcctgca ggaatacaac atggcagtgg 29280
tctcctcagc gatgattcgc accgcccgca gcataaggcg ccttgtcctc cgggcacagc 29340
agcgcaccct gatctcactt aaatcagcac agtaactgca gcacagcacc acaatattgt 29400
tcaaaatccc acagtgcaag gcgctgtatc caaagctcat ggcggggacc acagaaccca 29460
cgtggccatc ataccacaag cgcaggtaga ttaagtggcg acccctcata aacacgctgg 29520
acataaacat tacctctttt ggcatgttgt aattcaccac ctcccggtac catataaacc 29580
tctgattaaa catggcgcca tccaccacca tcctaaacca gctggccaaa acctgcccgc 29640
cggctataca ctgcagggaa ccgggactgg aacaatgaca gtggagagcc caggactcgt 29700
aaccatggat catcatgctc gtcatgatat caatgttggc acaacacagg cacacgtgca 29760
tacacttcct caggattaca agctcctccc gcgttagaac catatcccag ggaacaaccc 29820
attcctgaat cagcgtaaat cccacactgc agggaagacc tcgcacgtaa ctcacgttgt 29880
gcattgtcaa agtgttacat tcgggcagca gcggatgatc ctccagtatg gtagcgcggg 29940
tttctgtctc aaaaggaggt agacgatccc tactgtacgg agtgcgccga gacaaccgag 30000
atcgtgttgg tcgtagtgtc atgccaaatg gaacgccgga cgtagtcatt gaaatggatt 30060
ctcttgcgta ccttgtcgta cttctgccag cagaaagtgg ctcgggaaca gcagatacct 30120
ttcctcctgc tgtccttccg ctgctgacgc tcagtcatcc aactgaagta cagccattcc 30180
cgcaggttct ccagcagctc ctgtgcatct gatgaaacaa aagtcccgtc gatgcggatt 30240
ccccttaaaa catcagccag gacattgtag gccatcccaa tccagttaat gcatcctgat 30300
ctatcatgaa gaggaggtgg gggaagaact ggaagaacca tttttattcc aagcggtctc 30360
gaaggacgat aaagtgcaag tcacgcaggt gacagcgttc cccgccgctg tgctggtgga 30420
aacagacagc caggtcaaaa cccactctat tttcaaggtg ctcgactgtg gcttcgagca 30480
gtggctctac gcgtacatcc agcataagaa tcacattaaa ggctggacct ccatcgattt 30540
catcaatcat caggttacac tcattcacca tccccaggta attctcattt ttccagcctt 30600
ggattatttc tacaaattgt tggtgtaagt ccactccgca catgtggaaa agttcccaca 30660
gcgccccctc cactttcata atcaggcaga ccttcatatt agaaacagat cctgctgctc 30720
caccacctgc agcgtgttca aaacaacaag attcaatgag gttctgccct ctgccctcag 30780
ctcacgtctc agcgtcagct gcaaaaagtc actcaagtcc tcagccacta cagctgacaa 30840
ttcagagcca gggctaagcg tgggactggc aagcgtgagt gagtacttta atgctccaaa 30900
gctagcaccc aaaaactgca tgctggaata agctctcttt gtgtcaccgg tgatgccttc 30960
caataggtga gtgataaagc gaggtagttt ttctttaatc atttgagtaa tagaaaagtc 31020
ctctaaataa gtcactagga ccccaggaac cacaatgtgg tagctgacag cgtgtcgctc 31080
aagcatggtt agtagagatg agagtctgaa aaacagaaag catgcactaa accagagttg 31140
ccagtctcac tgaaggaaaa atcactctct ccagcagcaa agtgcccact gggtggccct 31200
ctcggacata caaaaatcga tccgtgtggt taaagagcag cacagttagc tcctgtcttc 31260
tcccagcaaa gatcacatcg gactgggtta gtatgcccct ggaatggtag tcattcaagg 31320
ccataaatct gccttggtag ccattaggaa tcagcacgct cactctcaag tgaaccaaaa 31380
ccaccccatg cggaggaatg tggaaagatt ctgggcaaaa aaaggtatat ctattgctag 31440
tcccttcctg gacgggagca atccctccag ggctatctat gaaagcatac agagattcag 31500
ccatagctca gcccgcttac cagtagacag agagcacagc agtacaagcg ccaacagcag 31560
cgactgacta cccactgacc cagctcccta tttaaaggca ccttacactg acgtaatgac 31620
caaaggtcta aaaaccccgc caaaaaaaca cacacgccct gggtgttttt cgcgaaaaca 31680
cttccgcgtt ctcacttcct cgtatcgatt tcgtgactca acttccgggt tcccacgtta 31740
cgtcacttct gcccttacat gtaactcagc cgtagggcgc catcttgccc acgtccaaaa 31800
tggcttccat gtccggccac gcctccgcgg cgaccgttag ccgtgcgtcg tgacgtcatt 31860
tgcatcaccg tttctcgtcc aatcagcgtt ggctccgccc caaaaccgtt aaaattcaaa 31920
agctcatttg catattaact tttgtttact ttgtggggta tattattgat gatg 31974
<210> 12
<211> 936
<212> PRT
<213> 人工序列
<220>
<223> Ad26HVRPtr1六邻体
<400> 12
Met Ala Thr Pro Ser Met Met Pro Gln Trp Ala Tyr Met His Ile Ala
1 5 10 15
Gly Gln Asp Ala Ser Glu Tyr Leu Ser Pro Gly Leu Val Gln Phe Ala
20 25 30
Arg Ala Thr Asp Thr Tyr Phe Ser Leu Gly Asn Lys Phe Arg Asn Pro
35 40 45
Thr Val Ala Pro Thr His Asp Val Thr Thr Asp Arg Ser Gln Arg Leu
50 55 60
Thr Leu Arg Phe Val Pro Val Asp Arg Glu Asp Thr Thr Tyr Ser Tyr
65 70 75 80
Lys Ala Arg Phe Thr Leu Ala Val Gly Asp Asn Arg Val Leu Asp Met
85 90 95
Ala Ser Thr Tyr Phe Asp Ile Arg Gly Val Leu Asp Arg Gly Pro Ser
100 105 110
Phe Lys Pro Tyr Ser Gly Thr Ala Tyr Asn Ser Leu Ala Pro Lys Gly
115 120 125
Ala Pro Asn Pro Ser Gln Trp Glu Glu Thr Ser Thr Asp Ala Thr Thr
130 135 140
Thr Thr Thr His Ser Phe Gly Leu Ala Ala Met Lys Gly Asp Asn Ile
145 150 155 160
Thr Ser Asp Gly Leu Gln Ile Gly Thr Asp Ala Thr Ser Gly Glu Glu
165 170 175
Lys Pro Ile Tyr Ala Asp Lys Thr Phe Gln Pro Glu Pro Gln Ile Gly
180 185 190
Glu Glu Ser Trp Thr Asp Thr Asp Gly Thr Asn Glu Lys Phe Gly Gly
195 200 205
Arg Val Leu Lys Lys Asp Thr Lys Met Lys Pro Cys Tyr Gly Ser Phe
210 215 220
Ala Arg Pro Thr Asn Glu Lys Gly Gly Gln Ala Lys Phe Lys Pro Val
225 230 235 240
Asn Glu Gly Glu Gln Pro Lys Asp Leu Asp Ile Asp Met Asn Phe Phe
245 250 255
Asp Gly Arg Asp Ala Ala Ala Asn Phe Thr Pro Glu Val Val Leu Tyr
260 265 270
Thr Glu Asn Val Asn Leu Glu Thr Pro Asp Thr His Val Val Tyr Lys
275 280 285
Pro Gly Thr Ser Asp Val Ser Ser His Val Asn Leu Gly Gln Gln Ser
290 295 300
Met Pro Asn Arg Pro Asn Tyr Ile Gly Phe Arg Asp Asn Phe Val Gly
305 310 315 320
Leu Met Tyr Tyr Asn Ser Thr Gly Asn Met Gly Val Leu Ala Gly Gln
325 330 335
Ala Ser Gln Leu Asn Ala Val Val Asp Leu Gln Asp Arg Asn Thr Glu
340 345 350
Leu Ser Tyr Gln Leu Leu Leu Asp Ser Leu Gly Asp Arg Thr Arg Tyr
355 360 365
Phe Ser Met Trp Asn Ser Ala Val Asp Ser Tyr Asp Pro Asp Val Arg
370 375 380
Ile Ile Glu Asn His Gly Val Glu Asp Glu Leu Pro Asn Tyr Cys Phe
385 390 395 400
Pro Leu Asp Ala Val Gly Ile Thr Lys Thr Tyr Gln Gly Ile Lys Thr
405 410 415
Gln Asn Gly Gln Thr Thr Thr Trp Glu Lys Asp Thr Ser Val Ser Thr
420 425 430
Ala Asn Glu Ile Gly Ile Gly Asn Asn Leu Ala Met Glu Ile Asn Leu
435 440 445
Gln Ala Asn Leu Trp Lys Ser Phe Leu Tyr Ser Asn Val Ala Leu Tyr
450 455 460
Leu Pro Asp Ser Tyr Lys Tyr Thr Pro Ala Asn Val Lys Leu Pro Ala
465 470 475 480
Asn Thr Asn Thr Tyr Glu Tyr Met Asn Gly Arg Val Val Ala Pro Ser
485 490 495
Leu Val Asp Ala Tyr Ile Asn Ile Gly Ala Arg Trp Ser Leu Asp Pro
500 505 510
Met Asp Asn Val Asn Pro Phe Asn His His Arg Asn Ala Gly Leu Arg
515 520 525
Tyr Arg Ser Met Leu Leu Gly Asn Gly Arg Tyr Val Pro Phe His Ile
530 535 540
Gln Val Pro Gln Lys Phe Phe Ala Ile Lys Asn Leu Leu Leu Leu Pro
545 550 555 560
Gly Ser Tyr Thr Tyr Glu Trp Asn Phe Arg Lys Asp Val Asn Met Ile
565 570 575
Leu Gln Ser Ser Leu Gly Asn Asp Leu Arg Val Asp Gly Ala Ser Val
580 585 590
Arg Phe Asp Ser Val Asn Leu Tyr Ala Thr Phe Phe Pro Met Ala His
595 600 605
Asn Thr Ala Ser Thr Leu Glu Ala Met Leu Arg Asn Asp Thr Asn Asp
610 615 620
Gln Ser Phe Asn Asp Tyr Leu Ser Ala Ala Asn Met Leu Tyr Pro Ile
625 630 635 640
Pro Ala Lys Ala Thr Asn Val Pro Ile Ser Ile Pro Ser Arg Asn Trp
645 650 655
Ala Ala Phe Arg Gly Trp Ser Phe Thr Arg Leu Lys Thr Lys Glu Thr
660 665 670
Pro Ser Leu Gly Ser Gly Phe Asp Pro Tyr Phe Val Tyr Ser Gly Ser
675 680 685
Ile Pro Tyr Leu Asp Gly Thr Phe Tyr Leu Asn His Thr Phe Lys Lys
690 695 700
Val Ser Ile Met Phe Asp Ser Ser Val Ser Trp Pro Gly Asn Asp Arg
705 710 715 720
Leu Leu Thr Pro Asn Glu Phe Glu Ile Lys Arg Ser Val Asp Gly Glu
725 730 735
Gly Tyr Asn Val Ala Gln Cys Asn Met Thr Lys Asp Trp Phe Leu Val
740 745 750
Gln Met Leu Ser His Tyr Asn Ile Gly Tyr Gln Gly Phe His Val Pro
755 760 765
Glu Gly Tyr Lys Asp Arg Met Tyr Ser Phe Phe Arg Asn Phe Gln Pro
770 775 780
Met Ser Arg Gln Val Val Asp Glu Ile Asn Tyr Lys Asp Tyr Lys Ala
785 790 795 800
Val Thr Leu Pro Phe Gln His Asn Asn Ser Gly Phe Thr Gly Tyr Leu
805 810 815
Ala Pro Thr Met Arg Gln Gly Gln Pro Tyr Pro Ala Asn Phe Pro Tyr
820 825 830
Pro Leu Ile Gly Gln Thr Ala Val Pro Ser Val Thr Gln Lys Lys Phe
835 840 845
Leu Cys Asp Arg Val Met Trp Arg Ile Pro Phe Ser Ser Asn Phe Met
850 855 860
Ser Met Gly Ala Leu Thr Asp Leu Gly Gln Asn Met Leu Tyr Ala Asn
865 870 875 880
Ser Ala His Ala Leu Asp Met Thr Phe Glu Val Asp Pro Met Asp Glu
885 890 895
Pro Thr Leu Leu Tyr Leu Leu Phe Glu Val Phe Asp Val Val Arg Val
900 905 910
His Gln Pro His Arg Gly Val Ile Glu Ala Val Tyr Leu Arg Thr Pro
915 920 925
Phe Ser Ala Gly Asn Ala Thr Thr
930 935
<210> 13
<211> 2808
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr1六邻体
<400> 13
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aatccaagtc aatgggaaga aacttccaca 420
gatgctacta ctactactac tcacagcttt ggcctggctg ctatgaaggg ggacaatatt 480
acatctgacg gtttgcagat aggaacagat gctacttctg gagaggaaaa acccatctat 540
gcagataaaa ctttccagcc agaacctcaa ataggggaag agtcatggac tgatactgac 600
ggaaccaatg aaaaattcgg aggaagagtc cttaaaaagg acactaaaat gaaaccatgc 660
tatggatctt ttgctagacc tactaatgag aaaggaggtc aggcaaagtt caaaccagtt 720
aatgaaggag aacaacctaa agatctggat atagatatga acttttttga tggtagagat 780
gcagctgcta actttactcc agaagtagtg ttgtacactg aaaatgttaa tcttgaaaca 840
ccagacactc atgtggttta caagccagga acctcagatg tgagttccca tgtcaatttg 900
ggtcagcagt ccatgccaaa cagacccaac tacattggct ttagggacaa ctttgtaggt 960
ctcatgtatt acaacagcac cggaaatatg ggtgtgctgg ctggtcaggc ttctcagttg 1020
aacgctgtgg tcgacttgca agacagaaac accgagttat cttaccagct attgctagat 1080
tctctgggtg acagaaccag atactttagc atgtggaact ctgcggtgga cagttacgat 1140
ccagatgtca ggatcattga aaatcacggt gtggaagatg aacttccaaa ctattgcttc 1200
ccattggacg ctgtgggtat tactaaaact tatcaaggta tcaaaacgca aaatggtcaa 1260
actacaacgt gggaaaagga caccagtgtt agtacggcca atgaaatagg cattggcaac 1320
aatcttgcca tggagatcaa cctgcaggcc aacctgtgga agagttttct gtactcgaac 1380
gtggccctgt acctgcccga ctcctacaag tacacgccgg ccaacgtcaa gctgcccgcc 1440
aacaccaaca cctacgagta catgaacggc cgcgtggtag ccccctcgct ggtggacgcc 1500
tacatcaaca tcggcgcccg ctggtcgttg gatcccatgg acaacgtcaa ccccttcaac 1560
caccaccgca atgcgggcct gcgctaccgc tccatgctgc tgggcaacgg ccgctacgtg 1620
cccttccaca tccaagtgcc ccaaaagttc tttgccatca agaacctgct cctgctcccg 1680
ggctcctaca cctacgagtg gaacttccgc aaggacgtca acatgatcct gcagagttcc 1740
ctcggcaacg acctgcgcgt cgacggcgcc tccgtccgct tcgacagcgt caacctatac 1800
gccactttct tccccatggc gcacaacacc gcttcaacct tggaagccat gctgcgcaac 1860
gacaccaacg accagtcctt caacgactac ctctcggccg ccaacatgct ctaccccatc 1920
ccggccaagg ccaccaacgt gcccatctcc atcccatcgc gcaactgggc cgccttccgc 1980
ggctggagtt tcacccggct caagaccaag gaaactcctt ccctcggctc gggtttcgac 2040
ccctactttg tctactcggg ctccatcccc tacctcgacg ggaccttcta cctcaaccac 2100
accttcaaga aggtctccat catgttcgac tcctcggtca gctggcccgg caacgaccgg 2160
ctgctcacgc cgaacgagtt cgagatcaag cgcagcgtcg acggggaggg ctacaacgtg 2220
gcccaatgca acatgaccaa ggactggttc ctcgtccaga tgctctccca ctacaacatc 2280
ggctaccagg gcttccacgt gcccgagggc tacaaggacc gcatgtactc cttcttccgc 2340
aacttccagc ccatgagcag gcaggtggtc gatgagatca actacaagga ctacaaggcc 2400
gtcaccctgc ccttccagca caataactcg ggcttcaccg gctacctcgc acccaccatg 2460
cgccaggggc agccctaccc cgccaacttc ccctacccgc tcatcggtca gacagccgtg 2520
ccctccgtca cccagaaaaa gttcctctgc gacagggtca tgtggcgcat ccccttctcc 2580
agcaacttca tgtccatggg cgccctcacc gacctgggtc agaacatgct ctacgccaac 2640
tcggcccacg cgctcgacat gaccttcgag gtggacccca tggatgagcc caccctcctc 2700
tatcttctct tcgaagtttt cgacgtggtc agagtacacc agccgcaccg cggcgtcatc 2760
gaggccgtct acctgcgcac gcccttctcc gccggcaacg ccaccacc 2808
<210> 14
<211> 2784
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr12六邻体
<400> 14
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aatcccagcc agtgggagca aaatgaaacc 420
aatgttaata aaacacacac ctttgggatg gcagccatga aaggagaagc tattgacaaa 480
aatggtctgc aaattggaac tgacgcggcg gatcaggata aaccaattta tgcagataaa 540
actttccagc cagaacctca agtaggagag gaagactgga ttgataaagc agatttctat 600
ggcggaagag ctcttaaaaa agacactaaa atgaaaccat gctatggatc ttttgctaga 660
cctactaatg agaaaggagg tcaggcaaag ttcaaaccag ttaatgaagg agaacaacct 720
aaagatctgg atatagatat gaacttcttt gacccaacca ctattaacac accagatgta 780
gtgctgtaca ctgaaaatgt taatcttgaa acaccagaca ctcatgtggt ttacaaggca 840
ggaacttcag atgacagttc tgaggtcaat ttggctcagc agtccatgcc aaacagaccc 900
aactacattg gctttaggga caactttgta ggtctcatgt attacaacag caccggaaat 960
atgggtgtgc tggctggtca ggcttctcag ttgaacgctg tggtcgactt gcaagacaga 1020
aacaccgagt tatcttacca gctattgcta gattctctgg gtgacagaac cagatacttt 1080
agcatgtgga actctgcggt ggacagttac gatccagatg tcaggatcat tgaaaatcac 1140
ggtgtggaag atgaacttcc aaactattgc ttcccattgg atggtgtggg cactaatact 1200
gcataccaag gcgttaaagt taagacaact aatggaaacg acacgtggga aaaagatgaa 1260
actgtttatg agtttaatca aattggcaag ggggatatct atgccatgga gatcaacctg 1320
caggccaacc tgtggaagag ttttctgtac tcgaacgtgg ccctgtacct gcccgactcc 1380
tacaagtaca cgccggccaa cgtcaagctg cccgccaaca ccaacaccta cgagtacatg 1440
aacggccgcg tggtagcccc ctcgctggtg gacgcctaca tcaacatcgg cgcccgctgg 1500
tcgttggatc ccatggacaa cgtcaacccc ttcaaccacc accgcaatgc gggcctgcgc 1560
taccgctcca tgctgctggg caacggccgc tacgtgccct tccacatcca agtgccccaa 1620
aagttctttg ccatcaagaa cctgctcctg ctcccgggct cctacaccta cgagtggaac 1680
ttccgcaagg acgtcaacat gatcctgcag agttccctcg gcaacgacct gcgcgtcgac 1740
ggcgcctccg tccgcttcga cagcgtcaac ctatacgcca ctttcttccc catggcgcac 1800
aacaccgctt caaccttgga agccatgctg cgcaacgaca ccaacgacca gtccttcaac 1860
gactacctct cggccgccaa catgctctac cccatcccgg ccaaggccac caacgtgccc 1920
atctccatcc catcgcgcaa ctgggccgcc ttccgcggct ggagtttcac ccggctcaag 1980
accaaggaaa ctccttccct cggctcgggt ttcgacccct actttgtcta ctcgggctcc 2040
atcccctacc tcgacgggac cttctacctc aaccacacct tcaagaaggt ctccatcatg 2100
ttcgactcct cggtcagctg gcccggcaac gaccggctgc tcacgccgaa cgagttcgag 2160
atcaagcgca gcgtcgacgg ggagggctac aacgtggccc aatgcaacat gaccaaggac 2220
tggttcctcg tccagatgct ctcccactac aacatcggct accagggctt ccacgtgccc 2280
gagggctaca aggaccgcat gtactccttc ttccgcaact tccagcccat gagcaggcag 2340
gtggtcgatg agatcaacta caaggactac aaggccgtca ccctgccctt ccagcacaat 2400
aactcgggct tcaccggcta cctcgcaccc accatgcgcc aggggcagcc ctaccccgcc 2460
aacttcccct acccgctcat cggtcagaca gccgtgccct ccgtcaccca gaaaaagttc 2520
ctctgcgaca gggtcatgtg gcgcatcccc ttctccagca acttcatgtc catgggcgcc 2580
ctcaccgacc tgggtcagaa catgctctac gccaactcgg cccacgcgct cgacatgacc 2640
ttcgaggtgg accccatgga tgagcccacc ctcctctatc ttctcttcga agttttcgac 2700
gtggtcagag tacaccagcc gcaccgcggc gtcatcgagg ccgtctacct gcgcacgccc 2760
ttctccgccg gcaacgccac cacc 2784
<210> 15
<211> 2826
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr13六邻体
<400> 15
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aattccagcc agtgggagca agcaaaacca 420
ggcaatgggg gaactatgga aacacacaca tatggtgtgg ccccaatggg cggagagaat 480
attacaaaag atggtcttca aattggaact gatgctacag cggatcagaa taaaccaatt 540
tatgctgaca aaactttcca gccagaacct caagtaggag aagaaaattg gcaagaaact 600
gaaagctttt atggtggtag ggctcttaaa aaagacacta aaatgaaacc atgctatgga 660
tcttttgcta gacctactaa tgagaaagga ggtcaggcaa agttcaaacc agttaatgaa 720
ggagaacaac ctaaagatct ggatatagat ctggctttct ttgatactcc cggtggcact 780
gtgaatggcc aagatgagta taaagcagac attgtcatgt acactgaaaa tgttaatctt 840
gaaacaccag acactcatgt ggtttacaag ccaggcaagg aagatgcaag ttctgaaatt 900
aacctggttc agcagtccat gccaaacaga cccaactaca ttggctttag ggacaacttt 960
gtaggtctca tgtattacaa cagcaccgga aatatgggtg tgctggctgg tcaggcttct 1020
cagttgaacg ctgtggtcga cttgcaagac agaaacaccg agttatctta ccagctattg 1080
ctagattctc tgggtgacag aaccagatac tttagcatgt ggaactctgc ggtggacagt 1140
tacgatccag atgtcaggat cattgaaaat cacggtgtgg aagatgaact tccaaactat 1200
tgcttcccat tggatggatc tggcactaac gccgcctatc aaggtgtaaa agtaaaaaat 1260
ggtgaagatg gtgatcttga gagcgagtgg gaaaatgatg atactgtggc agctcgaaat 1320
caaatatgca aaggcaatat tttcgccatg gagatcaacc tgcaggccaa cctgtggaag 1380
agttttctgt actcgaacgt ggccctgtac ctgcccgact cctacaagta cacgccggcc 1440
aacgtcaagc tgcccgccaa caccaacacc tacgagtaca tgaacggccg cgtggtagcc 1500
ccctcgctgg tggacgccta catcaacatc ggcgcccgct ggtcgttgga tcccatggac 1560
aacgtcaacc ccttcaacca ccaccgcaat gcgggcctgc gctaccgctc catgctgctg 1620
ggcaacggcc gctacgtgcc cttccacatc caagtgcccc aaaagttctt tgccatcaag 1680
aacctgctcc tgctcccggg ctcctacacc tacgagtgga acttccgcaa ggacgtcaac 1740
atgatcctgc agagttccct cggcaacgac ctgcgcgtcg acggcgcctc cgtccgcttc 1800
gacagcgtca acctatacgc cactttcttc cccatggcgc acaacaccgc ttcaaccttg 1860
gaagccatgc tgcgcaacga caccaacgac cagtccttca acgactacct ctcggccgcc 1920
aacatgctct accccatccc ggccaaggcc accaacgtgc ccatctccat cccatcgcgc 1980
aactgggccg ccttccgcgg ctggagtttc acccggctca agaccaagga aactccttcc 2040
ctcggctcgg gtttcgaccc ctactttgtc tactcgggct ccatccccta cctcgacggg 2100
accttctacc tcaaccacac cttcaagaag gtctccatca tgttcgactc ctcggtcagc 2160
tggcccggca acgaccggct gctcacgccg aacgagttcg agatcaagcg cagcgtcgac 2220
ggggagggct acaacgtggc ccaatgcaac atgaccaagg actggttcct cgtccagatg 2280
ctctcccact acaacatcgg ctaccagggc ttccacgtgc ccgagggcta caaggaccgc 2340
atgtactcct tcttccgcaa cttccagccc atgagcaggc aggtggtcga tgagatcaac 2400
tacaaggact acaaggccgt caccctgccc ttccagcaca ataactcggg cttcaccggc 2460
tacctcgcac ccaccatgcg ccaggggcag ccctaccccg ccaacttccc ctacccgctc 2520
atcggtcaga cagccgtgcc ctccgtcacc cagaaaaagt tcctctgcga cagggtcatg 2580
tggcgcatcc ccttctccag caacttcatg tccatgggcg ccctcaccga cctgggtcag 2640
aacatgctct acgccaactc ggcccacgcg ctcgacatga ccttcgaggt ggaccccatg 2700
gatgagccca ccctcctcta tcttctcttc gaagttttcg acgtggtcag agtacaccag 2760
ccgcaccgcg gcgtcatcga ggccgtctac ctgcgcacgc ccttctccgc cggcaacgcc 2820
accacc 2826
<210> 16
<211> 28287
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVRPtr1载体
<400> 16
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg aaggtaggtt 480
tgagtagtgg gcgtggctaa ggtgactata aaggcgggtg tcttacgagg gtctttttgc 540
ttttctgcag acatcatgaa cgggactggc ggggccttcg aaggggggct ttttagccct 600
tatttgacaa cccgcctgcc gggatgggcc ggagttcgtc agaatgtgat gggatcgacg 660
gtggatgggc gcccagtgct tccagcaaat tcctcgacca tgacctacgc gaccgtgggg 720
aactcgtcgc tcgacagcac cgccgcagcc gcggcagccg cagccgccat gacagcgacg 780
agactggcct cgagctacat gcccagcagc ggtagtagcc cctctgtgcc cagttccatc 840
atcgccgagg agaaactgct ggccctgctg gccgagctgg aagccctgag ccgccagctg 900
gccgccctga cccagcaggt gtccgagctc cgcgaacagc agcagcagca aaataaatga 960
ttcaataaac acagattctg attcaaacag caaagcatct ttattattta ttttttcgcg 1020
cgcggtaggc cctggtccac ctctcccgat cattgagagt gcggtggatt ttttccagga 1080
cccggtagag gtgggattgg atgttgaggt acatgggcat gagcccgtcc cgtgggtgga 1140
ggtagcacca ctgcatggcc tcgtgctctg gggtcgtgtt gtagatgatc cagtcatagc 1200
aggggcgctg ggcgtggtgc tggatgatgt ccttgaggag gagactgatg gccacgggga 1260
gccccttggt gtaggtgttg gcaaaacggt tgagctggga gggatgcatg cggggggaga 1320
tgatgtgcag tttggcctgg atcttgaggt tggcgatgtt gccacccaga tcccgccggg 1380
ggttcatgtt gtgcaggacc accagaacgg tgtagcccgt gcacttgggg aacttgtcat 1440
gcaacttgga agggaatgcg tggaagaatt tggagacgcc cttgtgcccg cccaggtttt 1500
ccatgcactc atccatgatg atggcaatgg gcccgtgggc tgcggctttg gcaaagacgt 1560
ttctggggtc agagacatcg taattatgct cctgggtgag atcatcataa gacattttaa 1620
tgaatttggg gcggagggtg ccagattggg ggacgatggt tccctcgggc cccggggcga 1680
agttcccctc gcagatctgc atctcccagg ctttcatctc ggaggggggg atcatgtcca 1740
cctgcggggc gatgaaaaaa acggtttccg gggcgggggt gatgagctgc gaggagagca 1800
ggtttctcaa cagctgggac ttgccgcacc cggtcgggcc gtagatgacc ccgatgacgg 1860
gttgcaggtg gtagttcaag gacatgcagc tgccgtcgtc ccggaggagg ggggccacct 1920
cgttgagctt gtctctgact tggaggtttt cccggacgag ctcgccgagg aggcggtccc 1980
cgcccagcga gagaagctct tgcagggaag caaagttttt caggggcttg agcccgtcgg 2040
ccatgggcat cttggcgagg gtctgcgaga ggagctccag gcggtcccag agctcggtga 2100
cgtgctctac ggcatctcga tccagcagac ttcctcgttt cgggggttgg gacgactgcg 2160
actgtagggc acgagacgat gggcgtccag cgcggccagc gtcatgtcct tccagggtct 2220
cagggtccgc gtgagggtgg tctccgtcac ggtgaagggg tgggccgcgg gctgggcgct 2280
tgcaagggtg cgcttgagac tcatcctgct ggtgctgaaa cgggcacggt cttcgccctg 2340
cgcgtcggcg agatagcagt tgaccatgag ctcgtagttg agggcctcgg cggcgtggcc 2400
cttggcgcgg agcttgccct tggaagagcg cccgcaggcg ggacagagga gggattgcag 2460
ggcgtagagc ttgggcgcga gaaagacgga ctcgggggcg aaggcgtccg ctccgcagtg 2520
ggcgcagacg gtctcgcact cgactagcca ggtgagctcg ggctgctcgg ggtcaaaaac 2580
cagttttccc ccgttctttt tgatgcgctt cttacctcgc gtctccatga gtctgtgtcc 2640
gcgctcggtg acaaacaggc tgtctgtgtc cccgtagacg gacttgatgg gcctgtcctg 2700
caggggcgtc ccgcggtcct cctcgtagag aaactcagac cactctgaga cgaaggcgcg 2760
cgtccacgcc aagacaaagg aggccacgtg cgaggggtag cggtcgttgt ccaccagggg 2820
gtccaccttt tccacggtat gcaggcacat gtccccctcc tccgcatcca agaaggtgat 2880
tggcttgtag gtgtaggcca cgtgacctgg ggttcccgac gggggggtat aaaagggggc 2940
gggtctgtgc tcgtcctcac tctcttccgc gtcgctgtcc acgagcgcca gctgttgggg 3000
taggtattcc ctctcaagag cgggcatgac ctcggcactc aggttgtcag tttctagaaa 3060
cgaggaggat ttgatgtggg cctgccctgc cgcgatgctt tttaggagac tttcatccat 3120
ctggtcagaa aagactattt ttttattgtc aagcttggtg gcgaaggagc catagagggc 3180
gtttgagaga agcttggcga tggatctcat ggtctgattt ttgtcacggt cggcgcgctc 3240
cttggccgcg atgttgagct ggacatattc gcgcgcgaca cacttccatt cggggaagac 3300
ggtggtgcgc tcgtcgggca cgatcctgac gcgccagccg cggttatgca gggtgaccag 3360
gtccacgctg gtggccacct cgccgcgcag gggctcgttg gtccagcaga gtctgccgcc 3420
cttgcgcgag cagaacgggg gcagcacatc aagcagatgc tcgtcagggg ggtccgcatc 3480
gatggtgaag atgcccggac agagttcctt gtcaaaataa tcgatttttg aggatgcatc 3540
gtccaaggcc atctgccact cgcgggcggc cagcgctcgc tcgtaggggt tgaggggcgg 3600
accccaaggc atgggatgcg tgagggcgga ggcgtacatg ccgcagatgt catagacata 3660
gatgggctcc gagaggatgc cgatgtaggt gggatagcag cgccccccgc ggatgcttgc 3720
gcgcacgtag tcatacaact cgtgcgaggg ggccaagaag gcggggccga gattggtgcg 3780
ctggggctgc tcggcgcgga agacgatctg gcgaaagatg gcgtgcgagt tggaggagat 3840
ggtgggccgt tggaagatgt taaagtgggc gtgaggcagg cggaccgagt cgcggatgaa 3900
gtgcgcgtag gagtcttgca gcttggcgac gagctcggcg gtgacgagga cgtccatggc 3960
gcagtagtcc agcgtttcgc ggatgatgtc ataactcgcc tctcctttct tctcccacag 4020
ctcgcggttg agggcgtatt cctcgtcatc cttccagtac tcccggagcg ggaatcctcg 4080
atcgtccgca cggtaagagc ccagcatgta gaaatggttc acggccttgt agggacagca 4140
gcccttctcc acggggaggg cgtaagcttg agcggccttg cggagcgagg tgtgcgtcag 4200
ggcaaaggtg tccctgacca tgactttcaa gaactggtac ttgaagtccg agtcgtcgca 4260
gccgccgtgc tcccagagct cgaaatcggt gcgcttcttc gagagggggt taggcagagc 4320
gaaagtgacg tcattgaaga gaatcttgcc tgcccgcggc atgaaattgc gggtgatgcg 4380
gaaagggccc gggacggagg ctcggttgtt gatgacctgg gcggcgagga cgatctcgtc 4440
aaagccgttg atgttgtgcc cgacgatgta gagttccatg aatcgcgggc ggcctttgat 4500
gtgcggcagc tttttgagct cctcgtaggt gaggtcctcg gggcattgca ggccgtgctg 4560
ctcgagcgcc cactcctgga gatgtgggtt ggcttgcatg aaggaagccc agagctcgcg 4620
ggccatgagg gtctggagct cgtcgcgaaa gaggcggaac tgctggccca cggccatctt 4680
ttctggggtg acgcagtaga aggtgagggg gtcccgctcc cagcgatccc agcgtaaacg 4740
cacggcgaga tcgcgagcga gggcgaccag ctctgggtcc ccggagaatt tcatgaccag 4800
catgaagggg acgagctgct tgccgaagga ccccatccag gtgtaggttt ctacatcgta 4860
ggtgacaaag agccgctccg tgcgaggatg agagccgatt gggaagaact ggatttcctg 4920
ccaccagttg gacgagtggc tgttgatgtg atgaaagtag aaatcccgcc ggcgaaccga 4980
gcactcgtgc tgatgcttgt aaaagcgtcc gcagtactcg cagcgctgca cgggctgtac 5040
ctcatccacg agatacacag cgcgtccctt gaggaggaac ttcaggagtg gcggccctgg 5100
ctggtggttt tcatgttcgc ctgcgtggga ctcaccctgg ggctcctcga ggacggagag 5160
gctgacgagc ccgcgcggga gccaggtcca gatctcggcg cggcgggggc ggagagcgaa 5220
gacgagggcg cgcagttggg agctgtccat ggtgtcgcgg agatccaggt ccgggggcag 5280
ggttctgagg ttgacctcgt agaggcgggt gagggcgtgc ttgagatgca gatggtactt 5340
gatttctacg ggtgagttgg tggtcgtgtc cacgcattgc atgagcccgt agctgcgcgg 5400
ggccacgacc gtgccgcggt gcgcttttag aagcggtgtc gcggacgcgc tcccggcggc 5460
agcggcggtt ccggccccgc gggcaggggc ggcagaggca cgtcggcgtg gcgctcgggc 5520
aggtcccggt gctgcgccct gagagcgctg gcgtgcgcga cgacgcggcg gttgacatcc 5580
tggatctgcc gcctctgcgt gaagaccacg ggccccgtga ctttgaacct gaaagacagt 5640
tcaacagaat caatctctgc gtcattgacg gcggcctgac gcaggatctc ttgcacgtcg 5700
cccgagttgt cctggtaggc gatctcggac atgaactgtt cgatctcctc ctcctggaga 5760
tcgccgcggc ccgcgcgctc cacggtggcg gcgaggtcat tggagatgcg acccatgagc 5820
tgcgagaagg cgcccaggcc gctctcgttc cagacgcggc tgtagaccac gtccccgtcg 5880
gcgtcgcgcg cgcgcatgac cacctgcgcg aggttgagct ccacgtgccg cgcaaagacg 5940
gcgtagttgc gcaggcgctg gaagaggtag ttgagggtgg tggcgatgtg ctcggtgacg 6000
aagaagtaca tgatccagcg gcgcaggggc atctcgctga tgtcgccgat ggcttccagc 6060
ctttccatgg cctcgtagaa gtccacggcg aagttgaaaa actgggcgtt gcgggccgag 6120
accgtgagct cgtcttccag gagccggatg agttcggcga tggtggcgcg cacctcgcgc 6180
tcgaaatccc cgggggcctc ctcctcttcc tcttcttcca tgacgacctc ttcttctatt 6240
tcttcctctg ggggcggtgg tggtggcggg ggccgacgac gacggcgacg caccgggaga 6300
cggtcgacga agcgctcgat catctccccg cggcggcgac gcatggtttc ggtgacggcg 6360
cgaccccgtt cgcgaggacg cagcgtgaag acgccgccgg tcatctcccg gtaatggggc 6420
gggtccccat tgggcagcga tagggcgctg acgatgcatc ttatcaattg cggtgtaggg 6480
gacgtgagcg cgtcgagatc gaccggatcg gagaatcttt cgaggaaagc gtctagccaa 6540
tcgcagtcgc aaggtaagct caaacacgta gcagccctgc ggacgctgtt agaattgcgg 6600
ttgctgatga tgtaattgaa gtaggcgttt ttgaggcggc ggatggtggc gaggaggacc 6660
aggtccttgg gtccagcttg ctggatgcgg agccgctcgg ccatgcccca ggcctggccc 6720
tgacaccggc tcaggttctt gtagtagtca tgcatgagcc tctcaatgtc atcactggct 6780
gaggcggagt cttccatgcg ggtgaccccg acgcccctga gcggctgcac gagcgccagg 6840
tcggcgacga cgcgctcggc gaggatggcc tgttgcacgc gggtgagggt gtcctggaag 6900
tcgtccatgt cgacgaagcg gtgataggcc ccggtgttga tggtgtaggt gcagttggcc 6960
atgagcgacc agttgacggt ctgcaggcct ggctgcacga cctcggagta cctgagccgc 7020
gagaaggcgc gcgagtcgaa gacgtagtcg ttgcaggtgc gcacgaggta ctggtatccg 7080
actaggaagt gcggcggcgg ctggcggtag agcggccagc gctgggtggc cggcgcgccc 7140
ggggccaggt cctcgagcat gaggcggtgg tagccgtaga ggtagcggga catccaggtg 7200
atgccggcgg cggtggtgga ggcgcgcggg aactcgcgga cgcggttcca gatgttgcgc 7260
agcggcagga aatagtccat ggtcggcacg gtctggccgg tgagacgcgc gcagtcattg 7320
acgctctaga ggcaaaaacg aaagcggttg agcgggctct tcctccgtag cctggcggaa 7380
cgcaaacggg ttaggccgcg tgtgtacccc ggttcgagtc ccctcgaatc aggctggagc 7440
cgcgactaac gtggtattgg cactcccgtc tcgacccgag cccgatagcc gccaggatac 7500
ggcggagagc cctttttgcc ggccgagtgg ggtcgctaga cttgaaagcg accgaaaacc 7560
ctgccgggta gtggctcgcg cccgtagtct ggagaagcat cgccagggtt gagtcgcggc 7620
agaacccggt tcgaggacgg ccgcggcgag cgggacttgg tcaccccgcc gatataaaga 7680
cccacagcca gccgacttct ccagttacgg gagcgagccc ccttttttct ttttgccaga 7740
tgcatcccgt cctgcgccaa atgcgtccca cccccccggc gaccaccgcg accgcggccg 7800
tagcaggcgc cggcgctagc cagccaccac agacagagat ggacttggaa gagggcgaag 7860
ggctggcaag actgggggcg ccgtccccgg agcgacatcc ccgcgtgcag ctgcagaagg 7920
acgtgcgccc ggcgtacgtg cctacgcaga acctgttcag ggaccgcagc ggggaggagc 7980
ccgaggagat gcgcgactgc cggtttcggg cgggcaggga gctgcgcgag ggcctggacc 8040
gccagcgcgt gctgcgcgac gaggatttcg agccgaacga gcagacgggg atcagccccg 8100
cacgcgcgca cgtggcggca gccaacctgg tgacggccta cgagcagacg gtgaagcagg 8160
agcgcaactt ccaaaagagt ttcaacaacc acgtgcgcac cctgatcgcg cgcgaggagg 8220
tggccctggg cctgatgcac ctgtgggacc tggcggaggc catcgtgcag aacccggaca 8280
gcaagcctct gacggcgcag ctgttcctgg tggtgcagca cagcagggac aacgaggcgt 8340
tcagggaggc gctgctgaac atcgccgagc ccgagggtcg ctggctgctg gagctgatta 8400
acatcttgca gagcatcgta gtgcaggagc gcagcctgag cctggccgag aaggtggcgg 8460
cgatcaacta ctcggtgctg agcctgggca agttttacgc gcgcaagatt tacaagacgc 8520
cgtacgtgcc catagacaag gaggtgaaga tagacagctt ttacatgcgc atggcgctca 8580
aggtgctgac gctgagcgac gacctgggcg tgtaccgcaa cgaccgcatc cacaaggccg 8640
tgagcacgag ccggcggcgc gagctgagcg accgcgagct gatgctgagt ctgcgccggg 8700
cgctggtagg gggcgccgcc ggcggcgagg agtcctactt cgacatgggt gcggacctgc 8760
attggcagcc gagccggcgc gccttggagg ccgcctacgg ttcagaggac ttggatgagg 8820
aagaggaaga ggaggaggat gcacccgctg cggggtactg acgcctccgt gatgtgtttt 8880
tagatgtccc agcaagcccc ggaccccgcc ataagggcgg cgctgcaaag ccagccgtcc 8940
ggtctagcat cggacgactg ggaggccgcg atgcaacgca tcatggccct gacgacccgc 9000
aaccccgagt cctttagaca acagccgcag gccaacagac tctcggccat tctggaggcg 9060
gtggtcccct ctcggaccaa ccccacgcac gagaaggtgc tggcgatcgt gaacgcgctg 9120
gcggagaaca aggccatccg tcccgacgag gccgggctgg tgtacaacgc cctgctggag 9180
cgcgtgggcc gctacaacag cacgaacgtg cagtccaacc tggatcggct ggtgacggac 9240
gtgcgcgagg ccgtggcgca gcgcgagcgg ttcaagaacg agggcctggg ctcgctggtg 9300
gcgctgaacg ccttcctggc gacgcagccg gcgaacgtgc cgcgcgggca ggacgattac 9360
accaacttta tcagcgcgct gcggctgatg gtgaccgagg tgccccagag cgaggtgtac 9420
cagtctggcc cggactactt tttccagacg agccggcagg gcttgcagac ggtgaacctg 9480
agccaggctt tcaagaatct gcgcgggctg tggggcgtgc aggcgcccgt gggcgaccgg 9540
tcaacggtga gcagcttgct gacgcccaac tcgcggctgc tgctgctgct gatcgcgccc 9600
ttcaccgaca gcggcagcgt gaaccgcaac tcgtacctgg gccatctgct gacgctgtac 9660
cgcgaggcca taggccaggc gcaggtggac gagcagacct tccaggagat cactagcgtg 9720
agccgcgcgc tggggcagaa cgacaccgac agtctgaggg ccaccctgaa ctttttgctg 9780
accaatagac agcagaagat cccggcgcag tacgcactgt cggccgagga ggaaaggatt 9840
ctgagatatg tgcagcagag cgtagggctg ttcctgatgc aggagggtgc cacccccagc 9900
gccgcgctgg acatgaccgc gcgcaacatg gaacctagca tgtacgccgc caaccggccg 9960
ttcatcaata agctgatgga ctacttgcac cgcgcggcgg ccatgaacac ggactacttt 10020
accaacgcca tcctgaaccc gcactggctc ccgccgccgg ggttctacac gggcgagtac 10080
gacatgcccg accccaacga cgggttcctg tgggacgacg tggacagcgc ggtgttctcg 10140
ccgacctttc aaaagcgcca ggaggcgccg ccgagcgagg gcgcggtggg gaggagcccc 10200
tttcctagct tagggagttt gcatagcttg ccgggctcgg tgaacagcgg cagggtgagc 10260
cggccgcgct tgctgggcga ggacgagtac ctgaacgact cgctgctgca gccgccgcgg 10320
gccaagaacg ccatggccaa taacgggata gagagtctgg tggacaaact gaaccgctgg 10380
aagacctacg ctcaggacca tagggacgcg cccgcgccgc ggcgacagcg ccacgaccgg 10440
cagcggggcc tggtgtggga cgacgaggac tcggccgacg atagcagcgt gttggacttg 10500
ggcgggagcg gtggggtcaa cccgttcgcg catctgcagc ccaaactggg gcgacggatg 10560
ttttgaatga aataaaactc accaaggcca tagcgtgcgt tctcttcctt gttagagatg 10620
aggcgcgcgg tggtgtcttc ctctcctcct ccctcgtacg agagcgtgat ggcgcaggcg 10680
accctggagg ttccgtttgt gcctccgcgg tatatggctc ctacggaggg cagaaacagc 10740
attcgttact cggagctggc tccgcagtac gacaccactc gcgtgtactt ggtggacaac 10800
aagtcggcgg acatcgcttc cctgaactac caaaacgacc acagcaactt cctgaccacg 10860
gtggtgcaga acaacgattt cacccccgcc gaggccagca cgcagacgat aaattttgac 10920
gagcggtcgc ggtggggcgg tgatctgaag accattctgc acactaacat gcccaatgtg 10980
aacgagtaca tgttcaccag caagtttaag gcgcgggtga tggtgtctag gaagcatcca 11040
gagggggtag ttgaaacaga tttgagtcag gataagcttg aatatgagtg gtttgagttt 11100
accctgcccg agggaaactt ttccgagacc atgaccatag acctgatgaa caacgccatc 11160
ttggaaaact acttgcaagt ggggcggcag aatggcgtgc tggagagcga tatcggagtc 11220
aagtttgaca gcagaaattt caagctgggc tgggacccgg tgaccaagct ggtgatgcca 11280
ggggtctaca cctacgaggc cttccacccg gacgtggtgc tgctgccggg ctgcggggtg 11340
gacttcaccg agagccgcct gagcaacctc ctgggcattc gcaagaagca acctttccaa 11400
gagggcttca gaatcatgta tgaggatcta gaaggtggca acatccccgc cctccttgat 11460
gtgcccaagt acttggaaag caagaagaaa gttgaagacg aaactaaaaa tgcagctgcg 11520
gccacagccg atacaaccac taggggtgat acatttgcaa ctccagcgca agagacagca 11580
gctgataaga aggtagaagt cttgcccatt gaaaaggatg agagtggtag aagttacaac 11640
ctgatccagg ggacccacga cacgctgtac cgcagttggt acctgtccta tacctacggg 11700
gaccccgaga agggggtgca gtcgtggacg ctgctcacca ccccggacgt tacctgcggc 11760
gcggagcaag tctactggtc actgccggac ctcatgcaag accccgtcac cttccgctcc 11820
acccagcaag tcagcaacta ccccgtggtc ggcgccgagc tcatgccctt ccgcgccaag 11880
agcttttaca acgacctcgc cgtctactcc cagctcatcc gcagctacac ctccctcacc 11940
cacgtcttca accgcttccc cgacaaccag atcctctgcc gcccgcccgc gcccaccatc 12000
accaccgtca gtgaaaacgt gcctgctctc acagatcacg ggacgctacc gctgcgcagc 12060
agtatccgcg gagtccagcg agtgaccgtc actgacgccc gtcgccgcac ctgtccctac 12120
gtctacaagg ccctgggcat agtcgcgccg cgcgtgcttt ccagtcgcac cttctaaaaa 12180
aatgtctatt ctcatctcgc ccagcaataa caccggctgg ggtcttacta gacccagcac 12240
catgtacgga ggagccaaga agcgctccca gcagcacccc gtccgcgtcc gcggccactt 12300
ccgcgctccc tggggcgcat acaagcgcgg gcggacttcc accgccgccg tgcgcaccac 12360
cgtcgacgac gtcatcgact cggtggtcgc cgacgcgcgc aactataccc ccgccccctc 12420
caccgtggac gcggtcatcg acagcgtggt ggccgacgcg cgcgactatg ccagacgcaa 12480
gagccggcgg cgacggatcg ccaggcgcca ccggagcacg cccgccatgc gcgccgcccg 12540
ggctctgctg cgccgcgcca gacgcacggg ccgccgggcc atgatgcgag ccgcgcgccg 12600
cgctgccact gcacccaccc ccgcaggcag gactcgcaga cgagcggccg ccgccgccgc 12660
tgcggccatc tctagcatga ccagacccag gcgcggaaac gtgtactggg tgcgcgactc 12720
cgtcacgggc gtgcgcgtgc ccgtgcgcac ccgtcctcct cgtccctgat ctaatgcttg 12780
tgtcctcccc cgcaagcgac gatgtcaaag cgcaaaatca aggaggagat gctccaggtc 12840
gtcgccccgg agatttacgg accaccccag gcggaccaga aaccccgcaa aatcaagcgg 12900
gttaaaaaaa aggatgaggt ggacgagggg gcagtagagt ttgtgcgcga gttcgctccg 12960
cggcggcgcg taaattggaa ggggcgcagg gtgcagcgcg tgttgcggcc cggcacggcg 13020
gtggtgttca cgcccggcga gcggtcctcg gtcaggagca agcgtagcta tgacgaggtg 13080
tacggcgacg acgacatcct ggaccaggcg gcggagcggg cgggcgagtt cgcctacggg 13140
aagcggtcgc gcgaagagga gctgatctcg ctgccgctgg acgaaagcaa ccccacgccg 13200
agcctgaagc ccgtgaccct gcagcaggtg ctgccccagg cggtgctgct gccgagccgc 13260
ggggtcaagc gcgagggcga gagcatgtac ccgaccatgc agatcatggt gcccaagcgc 13320
cggcgcgtgg aggacgtgct ggacaccgtg aaaatggatg tggagcccga ggtcaaggtg 13380
cgccccatca agcaggtggc gccgggcctg ggcgtgcaaa ccgtggacat tcagatcccc 13440
accgacatgg atgtcgacaa aaaaccctcg accagcatcg aggtgcaaac cgacccctgg 13500
ctcccagcct ccaccgctac cgtctccact tctaccgccg ccacggctac cgagcctccc 13560
aggaggcgaa gatggggcgc cgccagccgg ctgatgccca actacgtgtt gcatccttcc 13620
atcatcccga cgccgggcta ccgcggcacc cggtactacg ccagccgccg gcgcccagcc 13680
agcaaacgcc gccgccgcac cgccacccgc cgccgtctgg cccccgcccg cgtgcgccgc 13740
gtgaccacgc gccggggccg ctcgctcgtt ctgcccaccg tgcgctacca ccccagcatc 13800
ctttaatccg tgtgctgtga tactgttgca gagagatggc tctcacttgc cgcctgcgca 13860
tccccgtccc gaattaccga ggaagatccc gccgcaggag aggcatggca ggcagcggcc 13920
tgaaccgccg ccggcggcgg gccatgcgca ggcgcctgag tggcggcttt ctgcccgcgc 13980
tcatccccat aatcgccgcg gccattggca cgatcccggg catagcttcc gttgcgctgc 14040
aggcgtcgca gcgccgttga tgtgcgaata aagcctcttt agactctgac acacctggtc 14100
ctgtatattt ttagaatgga agacatcaat tttgcgtccc tggctccgcg gcacggcacg 14160
cggccgttca tgggcacctg gaacgagatc ggcaccagcc agctgaacgg gggcgccttc 14220
aattggagca gtgtctggag cgggcttaaa aatttcggct cgacgctccg gacctatggg 14280
aacaaggcct ggaatagtag cacggggcag ttgttgaggg aaaagctcaa agaccagaac 14340
ttccagcaga aggtggtgga cgggctggcc tcgggcatta acggggtggt ggacatcgcg 14400
aaccaggccg tgcagcgcga gataaacagc cgcctggacc cgcgaccgcc cacggtggtg 14460
gagatggaag atgcaactct tccgccgccc aagggcgaga agcggccgcg gcccgacgcg 14520
gaggagacga tcctgcaggt ggacgagccg ccctcgtacg aggaggccgt caaggccggc 14580
atgcccacca cgcgcatcat cgcgccgctg gccacgggtg taatgaaacc cgccaccctt 14640
gacctgcctc caccacccgc gcccgctcca ccgaaggcaa ctccggttgt gcaggccccc 14700
ccggtggcga ccgccgtgcg ccgcgtcccc gcccgccgcc aggcccagaa ctggcagagc 14760
acgctgcaca gtatcgtggg cctgggagtg aaaagtctga agcgccgccg atgctattga 14820
gagagaggaa agaggacact aaagggagag cttaacttgt atgtgcctta ccgccagaga 14880
acgcgcgaag atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg 14940
gcaggacgcc tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac 15000
gtacttcagc ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac 15060
cacggaccgg tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac 15120
gtactcgtac aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc 15180
cagcacttac tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc 15240
gggcacggcc tacaacagcc tggctcccaa gggtgccccc aatccaagtc aatgggaaga 15300
aacttccaca gatgctacta ctactactac tcacagcttt ggcctggctg ctatgaaggg 15360
ggacaatatt acatctgacg gtttgcagat aggaacagat gctacttctg gagaggaaaa 15420
acccatctat gcagataaaa ctttccagcc agaacctcaa ataggggaag agtcatggac 15480
tgatactgac ggaaccaatg aaaaattcgg aggaagagtc cttaaaaagg acactaaaat 15540
gaaaccatgc tatggatctt ttgctagacc tactaatgag aaaggaggtc aggcaaagtt 15600
caaaccagtt aatgaaggag aacaacctaa agatctggat atagatatga acttttttga 15660
tggtagagat gcagctgcta actttactcc agaagtagtg ttgtacactg aaaatgttaa 15720
tcttgaaaca ccagacactc atgtggttta caagccagga acctcagatg tgagttccca 15780
tgtcaatttg ggtcagcagt ccatgccaaa cagacccaac tacattggct ttagggacaa 15840
ctttgtaggt ctcatgtatt acaacagcac cggaaatatg ggtgtgctgg ctggtcaggc 15900
ttctcagttg aacgctgtgg tcgacttgca agacagaaac accgagttat cttaccagct 15960
attgctagat tctctgggtg acagaaccag atactttagc atgtggaact ctgcggtgga 16020
cagttacgat ccagatgtca ggatcattga aaatcacggt gtggaagatg aacttccaaa 16080
ctattgcttc ccattggacg ctgtgggtat tactaaaact tatcaaggta tcaaaacgca 16140
aaatggtcaa actacaacgt gggaaaagga caccagtgtt agtacggcca atgaaatagg 16200
cattggcaac aatcttgcca tggagatcaa cctgcaggcc aacctgtgga agagttttct 16260
gtactcgaac gtggccctgt acctgcccga ctcctacaag tacacgccgg ccaacgtcaa 16320
gctgcccgcc aacaccaaca cctacgagta catgaacggc cgcgtggtag ccccctcgct 16380
ggtggacgcc tacatcaaca tcggcgcccg ctggtcgttg gatcccatgg acaacgtcaa 16440
ccccttcaac caccaccgca atgcgggcct gcgctaccgc tccatgctgc tgggcaacgg 16500
ccgctacgtg cccttccaca tccaagtgcc ccaaaagttc tttgccatca agaacctgct 16560
cctgctcccg ggctcctaca cctacgagtg gaacttccgc aaggacgtca acatgatcct 16620
gcagagttcc ctcggcaacg acctgcgcgt cgacggcgcc tccgtccgct tcgacagcgt 16680
caacctatac gccactttct tccccatggc gcacaacacc gcttcaacct tggaagccat 16740
gctgcgcaac gacaccaacg accagtcctt caacgactac ctctcggccg ccaacatgct 16800
ctaccccatc ccggccaagg ccaccaacgt gcccatctcc atcccatcgc gcaactgggc 16860
cgccttccgc ggctggagtt tcacccggct caagaccaag gaaactcctt ccctcggctc 16920
gggtttcgac ccctactttg tctactcggg ctccatcccc tacctcgacg ggaccttcta 16980
cctcaaccac accttcaaga aggtctccat catgttcgac tcctcggtca gctggcccgg 17040
caacgaccgg ctgctcacgc cgaacgagtt cgagatcaag cgcagcgtcg acggggaggg 17100
ctacaacgtg gcccaatgca acatgaccaa ggactggttc ctcgtccaga tgctctccca 17160
ctacaacatc ggctaccagg gcttccacgt gcccgagggc tacaaggacc gcatgtactc 17220
cttcttccgc aacttccagc ccatgagcag gcaggtggtc gatgagatca actacaagga 17280
ctacaaggcc gtcaccctgc ccttccagca caataactcg ggcttcaccg gctacctcgc 17340
acccaccatg cgccaggggc agccctaccc cgccaacttc ccctacccgc tcatcggtca 17400
gacagccgtg ccctccgtca cccagaaaaa gttcctctgc gacagggtca tgtggcgcat 17460
ccccttctcc agcaacttca tgtccatggg cgccctcacc gacctgggtc agaacatgct 17520
ctacgccaac tcggcccacg cgctcgacat gaccttcgag gtggacccca tggatgagcc 17580
caccctcctc tatcttctct tcgaagtttt cgacgtggtc agagtacacc agccgcaccg 17640
cggcgtcatc gaggccgtct acctgcgcac gcccttctcc gccggcaacg ccaccaccta 17700
agcatgagcg gctccagcga acgagagctc gcggccatcg tgcgcgacct gggctgcggg 17760
ccctactttt tgggcaccca cgacaagcgc ttcccgggct ttctcgccgg cgacaagctg 17820
gcctgcgcca tcgtcaacac ggccggccgc gagaccggag gcgtgcactg gctcgccttc 17880
ggctggaacc cgcgctcgcg cacctgctac atgttcgacc cctttgggtt ctcggaccgc 17940
cggctcaagc agatttacag cttcgagtac gaggccatgc tgcgccgcag cgccctggcc 18000
tcctcgcccg accgctgtct cagcctcgag cagtccactc agaccgtgca ggggcccgac 18060
tccgccgcct gcggactctt ctgttgcatg ttcttgcatg ccttcgtgca ctggcccgac 18120
cgacccatgg acggaaaccc caccatgaac ttgctgacgg gggtgcccaa cggcatgcta 18180
caatcgccac aggtgctgcc caccctcagg cgcaaccagg aggaactcta ccgcttcctc 18240
gcgcgccact ccccttactt tcgctcccac cgcgccgcca tcgaacacgc caccgctttt 18300
gacaaaatga aacaactgcg tgtatctcaa taaacagcac ttttatttta catgcactgg 18360
agtatatgca agttatttaa aagtcgaagg ggttctcgcg ctcgtcgttg tgcgccgcgc 18420
tggggagggc cacgttgcgg tactggtact tgggctgcca cttgaactcg gggatcacca 18480
gtttgggcac tggggtctcg gggaaggtct cgctccacat gcgccggctc atctgcaggg 18540
cgcccagcat gtccggggcg gagatcttga aatcgcagtt ggggccggtg ctctgcgcgc 18600
gcgagttgcg gtacacgggg ttgcagcact ggaacaccat cagactgggg tacttcacac 18660
tagccagcac gctcttgtcg ctgatctgat ccttgtccag atcctcggcg ttgctcaggc 18720
cgaacggggt catcttgcac agctggcgtc ccaggaaggg cacgctctga ggcttgtggt 18780
tacactcgca gtgcacgggc atcagcatca tccccgcgcc gcgctgcata ttcgggtaga 18840
gggccttgac aaaggccgcg atctgcttga aagcttgctg ggccttggcc ccctcgctga 18900
aaaacaggcc gcagctcttc ccgctgaact ggttattccc acacccggca tcctgcacgc 18960
agcagcgcgc gtcatggctg gtcagttgca ccacgctccg tccccagcgg ttctgggtca 19020
ccttagcctt gctgggctgc tccttcaacg cgcgctgccc gttctcgctg gtcacatcca 19080
tctccaccac gtggtccttg tggatcatca tcgtcccgtg cagacacttg agctggcctt 19140
ccacctcggt gcagccgtga tcccacaggg cgcaaccggt gcactcccag ttcttgtgcg 19200
caatcccgct gtggctgaag atgtaacctt gcaacatgcg gcccatgatg gtgctaaatg 19260
ctttctgggt ggtgaaggtc agttgcatcc cgcgggcctc ctcgttcatc caggtctggc 19320
acatcttctg gaagatctcg gtctgctcgg gcatgagctt gtaagcatcg cgcaggccgc 19380
tgtcgacgcg gtagcgttcc atcagcacgt tcatggtatc catgcccttc tcccaggacg 19440
agaccagagg cagactcaga gggttgcgta cgttcaggac accgggggtc gcgggctcga 19500
cgatgcgttt tccgtccttg ccttccttca atagaaccgg cggctggctg aatcccactc 19560
ccacgatcac ggcatcttcc tggggcatct cttcgtcggg gtctaccttg gtcacatgct 19620
tggtctttct ggcttgcttc ttttttggag ggctgtccac ggggagcacg tcctcctcgg 19680
aagacccgga gcccacccgc tgatactttc ggcgcttggt gggcagagga ggtggcggcg 19740
aggggctcct ctcctgctcc ggcggatagc gcgccgaccc gtggccccgg ggcggagtgg 19800
cctctcggcc catgaaccgg cgcacgtcct gactgccgcc ggccattgtt tcctagggga 19860
agatggagga gcagccgcgt aagcaggagc aggaggagga cttaaccacc cacgagcaac 19920
ccaaaatcga gcaggacctg ggcttcgaag agccggctcg tctagaaccc ccacaggatg 19980
aacaggagca cgagcaagac gcaggccagg aggagaccga cgctgggctc gagcatggct 20040
acctgggagg agaggaggat gtgctgctga aacacctgca gcgccagtcc ctcatcctcc 20100
gggacgccct ggccgaccgg agcgaaaccc ccctcagcgt cgaggagctg tgtcgggcct 20160
acgagctcaa cctcttctcg ccgcgcgtac cccccaaacg ccagcccaac ggcacctgcg 20220
agcccaaccc gcgtctcaac ttctatcccg tctttgcggt ccccgaagcc ctcgccacct 20280
atcacatctt tttcaagaac caaaagatcc ccgtctcctg ccgcgccaac cgcaccagcg 20340
ccgacgcgct cctcgctttg gggcccggcg cgcgcatacc tgatatcgct tccctggaag 20400
aggtgcccaa gatcttcgaa gggctcggtc gggacgagac gcgcgcggcg aacgctctga 20460
aagaaacagc agaggaagag ggtcacacta gcgccctggt agagttggaa ggcgacaacg 20520
ccaggctggc cgtgctcaag cgcagcgtcg agcttaccca cttcgcctac cccgccgtca 20580
acctcccgcc caaggtcatg cgtcgcatca tggatcagct catcatgccc cacatcgagg 20640
ccctcgatga aagtcaggag cagcgccccg aggacgcccg gcccgtggtc agcgacgaga 20700
tgctcgcgcg ctggctcggg acccgcgacc cccaggcttt ggaacagcgg cgcaaactca 20760
tgctggccgt ggtcctggtc acccttgagc tcgaatgcat gcgccgcttt ttcagcgacc 20820
ccgagaccct gcgcaaggtc gaggagaccc tgcactacac tttcaggcac ggtttcgtca 20880
ggcaggcctg caagatctcc aacgtggagc tgaccaacct ggtctcctgc ctggggatcc 20940
tgcacgagaa ccgcctgggc cagaccgtgc tccactctac cctgaagggc gaggcgcggc 21000
gggactatgt ccgcgactgc gtctttctct ttctctgcca cacatggcaa gcggccatgg 21060
gcgtgtggca gcagtgtctc gaggacgaga acctaaagga gctggacaag cttcttgcta 21120
gaaaccttaa aaagctgtgg acgggcttcg acgagcgcac cgtcgcctcg gacctggccg 21180
agatcgtctt ccccgagcgc ctgagacaga cgctgaaagg cgggctgccc gacttcatga 21240
gccagagcat gttgcaaaac taccgcactt tcattcttga gcgatcaggc atcctgcccg 21300
ccacctgcaa cgccttcccc tccgactttg taccgctgag ctaccgcgag tgtcccccgc 21360
cgctgtggag ccactgctac ctcttgcagc tggccaacta catcgcctac cactcggacg 21420
tgatcgagga cgtgagcggc gaggggctgc tcgagtgcca ctgtcgctgc aacctgtgct 21480
ccccgcatcg ctccctggtc tgcaaccccc agctcctgag cgagacccag gtcatcggta 21540
ccttcgagct gcaaggtccg caggagtcca ccgctccgct gaaactcacg ccggggttgt 21600
ggacttccgc gtacctgcgc aaatttgtac ccgaagacta ccacgcccat gagataaagt 21660
tctttgagga ccaatcgcgt ccgcagcacg cggatctcac ggcctgcgtc atcacccagg 21720
gcgcgatcct cgcccaattg cacgccatcc aaaaatcccg ccaagagttt cttctgaaaa 21780
agggtagagg ggtctacctg gacccccaga cgggcgaggt gctcaacccg ggtctccccc 21840
agcatgccga ggaagaagca ggagccgcta gtggaggaga tggaagaaga atgggacagc 21900
caggcagagg aggacgaatg ggaggaggag acagaggagg aagaattgga agaggtggaa 21960
gaggagcagg caacagagca gcccgtcgcc gcaccatccg cgccggcagc cccgccggtc 22020
acggatacaa cctccgctcc ggtcaagcct cctcgtagat gggatcaagt gaagggtgac 22080
ggtaagcacg agcggcaggg ctaccgatca tggagggccc acaaagccgc gatcatcgcc 22140
tgcttgcaag actgcggggg gaacatcgct ttcgcccgcc gctacctgct cttccaccgc 22200
ggggtgaaca tcccccgcaa cgtgttgcat tactaccgtc accttcacag ctaagaaaaa 22260
gcaagtcaaa ggagtcgccg gaggaggagg aggaggcctg aggatcgcgg cgaacgagcc 22320
cttgaccacc agggagctga ggaaccggat cttccccact ctttatgcca tttttcagca 22380
gagtcgaggt cagcagcaag agctcaaagt aaaaaaccgg tctctgcgct cgctcacccg 22440
cagttgcttg taccacaaaa acgaagatca gctgcagcgc actctcgaag acgccgaggc 22500
tctgttccac aagtactgcg cgctcactct taaagactaa ggcgcgccca cccggaaaaa 22560
aggcgggaat tacctcatcg ccaccatgag caaggagatt cccacccctt acatgtggag 22620
ctatcagccc caaatgggcc tggccgcggg cgcctcccag gactactcca cccgcatgaa 22680
ctggctcagt gccggcccct cgatgatctc acgggtcaac ggggtccgca gtcatcgaaa 22740
ccagatattg ttggagcagg cggcggtcac ctccacgccc agggcaaagc tcaacccgcg 22800
taattggccc tccaccctgg tgtatcagga aatccccggg ccgactaccg tactacttcc 22860
gcgtgacgca ctggccgaag tccgcatgac taactcaggt gtccagctgg ccggcggcgc 22920
ttcccggtgc ccgctccgcc cacaatcggg tataaaaacc ctggtgatcc gaggcagagg 22980
cacacagctc aacgacgagt tggtgagctc ttcgatcggt ctgcgaccgg acggagtgtt 23040
ccaactagcc ggagccggga gatcctcctt cactcccaac caggcctacc tgaccttgca 23100
gagcagctct tcggagcctc gctccggagg catcggaacc ctccagtttg tggaggagtt 23160
tgtgccctcg gtctacttca accccttctc gggatcgcca ggcctctacc cggacgagtt 23220
cataccgaac ttcgacgcag tgagagaagc ggtggacggc tacgactgaa tgtcccatgg 23280
tgactcggct gagctcgctc ggttgaggca tctggaccac tgccgccgcc tgcgctgctt 23340
cgcccgggag agctgcggac tcatctactt tgagtttccc gaggagcacc ccaacggccc 23400
tgcacacgga gtgcggatca ccgtagaggg caccaccgag tctcacctgg tcaggttctt 23460
cacccagcaa cccttcctgg tcgagcggga ccggggcgcc accacctaca ccgtctactg 23520
catctgtcca accccgaagt tgcatgagaa tttttgttgt actctttgtg gtgagtttaa 23580
taaaagctaa actcttgcaa tactctggac cttgtcgtcg tcaactcaac gagaccgtct 23640
acctcaccaa ccagactgag gtaaaactca cctgcagacc acacaagacc tatatcatct 23700
ggttcttcga gaacacctca tttgcagtct ccaacactca ctgcactagt ccatgaactg 23760
atgttgatta aaagcccaaa aaccaatcag ccccttcccc catttcccca tcccccaatt 23820
actcataaaa aataaatcat tggaattaat cattcaataa agatcactta cttgaaatct 23880
gaaagtatgt ctctggtgta gttgttcagc agcacctcgg taccctcctc ccagctctgg 23940
tactccagtc cccggcgggc ggcgaacttc ctccacacct tgaaagggat gtcaaattcc 24000
tggtccacaa ttttcattgt cttccctctc agatggcaaa gaggctccgg gtggaagatg 24060
acttcaaccc cgtctacccc tatggctacg cgcggaatca gaatatcccc ttcctcactc 24120
ccccctttgt ctcctccgat ggattcaaaa acttcccccc tggggtcctg tcacttaaac 24180
tggctgatcc aatcaccatc aacaatgggg atgtctcact taaggtggga gggggacttg 24240
ctgtagagca acagactggt aacctaagcg taaaccctga tgcacccttg caagttgcaa 24300
gtgataagct acagcttgct ctggctcctc cattcgaggt cagagatgga aagcttgctt 24360
taaaggcagg taatggatta aaagtactag ataattccat tactggattg actggattat 24420
tgaatacact tgtggtatta actggaaggg gaataggaac ggaggaatta aaaaatgacg 24480
atggtgtaac aaacaaagga gtcggcttgc gtgtaagact tggagatgac ggcgggctga 24540
catttgataa aaagggtgat ttagtagcct ggaataaaaa agatgacagg cgcaccctgt 24600
ggacaacccc tgacacatct ccaaattgca aaatgagtac agaaaaggat tctaaactta 24660
cgttgacact tacaaagtgt ggaagtcagg ttctgggaaa tgtatcttta cttgcagtta 24720
caggtgaata tcatcaaatg actgctacta caaagaagga tgtaaaaata tctttactat 24780
ttgatgagaa tggaattcta ttaccatctt cgtcccttag caaagattat tggaattaca 24840
gaagtgatga ttctattgta tctcaaaaat ataataatgc agttccattc atgccaaacc 24900
tgacagctta tccaaaacca agcgctcaaa atgcaaaaaa ctattcaaga actaaaatca 24960
taagtaatgt ctacttaggt gctcttacct accaacctgt aattatcact attgcattta 25020
atcaggaaac tgaaaatgga tgtgcttatt ctataacatt taccttcact tggcaaaaag 25080
actattctgc ccaacagttt gatgttacat cttttacctt ctcatatctt acccaagaga 25140
acaaagacaa agactaataa aatgttttga actgaattta tgaatcttta tttattttta 25200
caccagcacg ggtagtcagt ttcccaccac cagcccattt cacagtgtaa acagtccttt 25260
ctccccggct ggccttaaaa agcatcatat catgggtaac agacatattc ttaggtgtta 25320
tattccacac ggtttcctgt cgagccaaac gctcatcagt gatattaata aactccccgg 25380
gcagctcact taagttcatg tcgctgtcca gctgctgagc cacaggctgc tgtccaactt 25440
gcggttgctt aacgggcggc gaaggagaag tccacgccta catgggggta gagtcataat 25500
cgtgcatcag gatagggcgg tggtgctgca gcagcgcgcg aataaactgc tgccgccgcc 25560
gctccgtcct gcaggaatac aacatggcag tggtctcctc agcgatgatt cgcaccgccc 25620
gcagcataag gcgccttgtc ctccgggcac agcagcgcac cctgatctca cttaaatcag 25680
cacagtaact gcagcacagc accacaatat tgttcaaaat cccacagtgc aaggcgctgt 25740
atccaaagct catggcgggg accacagaac ccacgtggcc atcataccac aagcgcaggt 25800
agattaagtg gcgacccctc ataaacacgc tggacataaa cattacctct tttggcatgt 25860
tgtaattcac cacctcccgg taccatataa acctctgatt aaacatggcg ccatccacca 25920
ccatcctaaa ccagctggcc aaaacctgcc cgccggctat acactgcagg gaaccgggac 25980
tggaacaatg acagtggaga gcccaggact cgtaaccatg gatcatcatg ctcgtcatga 26040
tatcaatgtt ggcacaacac aggcacacgt gcatacactt cctcaggatt acaagctcct 26100
cccgcgttag aaccatatcc cagggaacaa cccattcctg aatcagcgta aatcccacac 26160
tgcagggaag acctcgcacg taactcacgt tgtgcattgt caaagtgtta cattcgggca 26220
gcagcggatg atcctccagt atggtagcgc gggtttctgt ctcaaaagga ggtagacgat 26280
ccctactgta cggagtgcgc cgagacaacc gagatcgtgt tggtcgtagt gtcatgccaa 26340
atggaacgcc ggacgtagtc attgaaatgg attctcttgc gtaccttgtc gtacttctgc 26400
cagcagaaag tggctcggga acagcagata cctttcctcc tgctgtcctt ccgctgctga 26460
cgctcagtca tccaactgaa gtacagccat tcccgcaggt tctccagcag ctcctgtgca 26520
tctgatgaaa caaaagtccc gtcgatgcgg attcccctta aaacatcagc caggacattg 26580
taggccatcc caatccagtt aatgcatcct gatctatcat gaagaggagg tgggggaaga 26640
actggaagaa ccatttttat tccaagcggt ctcgaaggac gataaagtgc aagtcacgca 26700
ggtgacagcg ttccccgccg ctgtgctggt ggaaacagac agccaggtca aaacccactc 26760
tattttcaag gtgctcgact gtggcttcga gcagtggctc tacgcgtaca tccagcataa 26820
gaatcacatt aaaggctgga cctccatcga tttcatcaat catcaggtta cactcattca 26880
ccatccccag gtaattctca tttttccagc cttggattat ttctacaaat tgttggtgta 26940
agtccactcc gcacatgtgg aaaagttccc acagcgcccc ctccactttc ataatcaggc 27000
agaccttcat attagaaaca gatcctgctg ctccaccacc tgcagcgtgt tcaaaacaac 27060
aagattcaat gaggttctgc cctctgccct cagctcacgt ctcagcgtca gctgcaaaaa 27120
gtcactcaag tcctcagcca ctacagctga caattcagag ccagggctaa gcgtgggact 27180
ggcaagcgtg agtgagtact ttaatgctcc aaagctagca cccaaaaact gcatgctgga 27240
ataagctctc tttgtgtcac cggtgatgcc ttccaatagg tgagtgataa agcgaggtag 27300
tttttcttta atcatttgag taatagaaaa gtcctctaaa taagtcacta ggaccccagg 27360
aaccacaatg tggtagctga cagcgtgtcg ctcaagcatg gttagtagag atgagagtct 27420
gaaaaacaga aagcatgcac taaaccagag ttgccagtct cactgaagga aaaatcactc 27480
tctccagcag caaagtgccc actgggtggc cctctcggac atacaaaaat cgatccgtgt 27540
ggttaaagag cagcacagtt agctcctgtc ttctcccagc aaagatcaca tcggactggg 27600
ttagtatgcc cctggaatgg tagtcattca aggccataaa tctgccttgg tagccattag 27660
gaatcagcac gctcactctc aagtgaacca aaaccacccc atgcggagga atgtggaaag 27720
attctgggca aaaaaaggta tatctattgc tagtcccttc ctggacggga gcaatccctc 27780
cagggctatc tatgaaagca tacagagatt cagccatagc tcagcccgct taccagtaga 27840
cagagagcac agcagtacaa gcgccaacag cagcgactga ctacccactg acccagctcc 27900
ctatttaaag gcaccttaca ctgacgtaat gaccaaaggt ctaaaaaccc cgccaaaaaa 27960
acacacacgc cctgggtgtt tttcgcgaaa acacttccgc gttctcactt cctcgtatcg 28020
atttcgtgac tcaacttccg ggttcccacg ttacgtcact tctgccctta catgtaactc 28080
agccgtaggg cgccatcttg cccacgtcca aaatggcttc catgtccggc cacgcctccg 28140
cggcgaccgt tagccgtgcg tcgtgacgtc atttgcatca ccgtttctcg tccaatcagc 28200
gttggctccg ccccaaaacc gttaaaattc aaaagctcat ttgcatatta acttttgttt 28260
actttgtggg gtatattatt gatgatg 28287
<210> 17
<211> 33008
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVR5.luc
<400> 17
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat ccttgcgaat gggatgaagc tgctactgct cttgaaataa 18000
acctagaaga agaggacgat gacaacgaag acgaagtaga cgagcaagct gagcagcaaa 18060
aaactcacgt atttgggcag gcgccttatt ctggtataaa tattacaaag gagggtattc 18120
aaataggtgt cgaaggtcaa acacctaaat atgccgataa aactttccag ccagaacctc 18180
aaataggaga atctcagtgg tacgaaactg aaattaatca tgcagctggg agagtcctta 18240
aaaaggacac taaaatgaaa ccatgctatg gatcttttgc tagacctact aatgagaaag 18300
gaggtcaggc aaagttcaaa ccagttaatg aaggagaaca acctaaagat ctggatatag 18360
atatgcaatt tttctcaact actgaggcga ccgcaggcaa tggtgataac ttgactccta 18420
aagtggtatt gtacactgaa aatgttaatc ttgaaacacc agacactcat gtggtttaca 18480
agcccactat taaggaaggt aactcacgag aactaatggg ccagcagtcc atgccaaaca 18540
gacccaacta cattggcttt agggacaact ttgtaggtct catgtattac aacagcaccg 18600
gaaatatggg tgtgctggct ggtcaggctt ctcagttgaa cgctgtggtc gacttgcaag 18660
acagaaacac cgagttatct taccagctat tgctagattc tctgggtgac agaaccagat 18720
actttagcat gtggaactct gcggtggaca gttacgatcc agatgtcagg atcattgaaa 18780
atcacggtgt ggaagatgaa cttccaaact attgcttccc attgggaggt gtgattaata 18840
cagagactct taccaaggta aaacctaaaa caggtcagga aaatggatgg gaaaaagatg 18900
ctacagaatt ttcagataaa aatgaaataa gagttggaaa taattttgcc atggagatca 18960
acctgcaggc caacctgtgg aagagttttc tgtactcgaa cgtggccctg tacctgcccg 19020
actcctacaa gtacacgccg gccaacgtca agctgcccgc caacaccaac acctacgagt 19080
acatgaacgg ccgcgtggta gccccctcgc tggtggacgc ctacatcaac atcggcgccc 19140
gctggtcgtt ggatcccatg gacaacgtca accccttcaa ccaccaccgc aatgcgggcc 19200
tgcgctaccg ctccatgctg ctgggcaacg gccgctacgt gcccttccac atccaagtgc 19260
cccaaaagtt ctttgccatc aagaacctgc tcctgctccc gggctcctac acctacgagt 19320
ggaacttccg caaggacgtc aacatgatcc tgcagagttc cctcggcaac gacctgcgcg 19380
tcgacggcgc ctccgtccgc ttcgacagcg tcaacctata cgccactttc ttccccatgg 19440
cgcacaacac cgcttcaacc ttggaagcca tgctgcgcaa cgacaccaac gaccagtcct 19500
tcaacgacta cctctcggcc gccaacatgc tctaccccat cccggccaag gccaccaacg 19560
tgcccatctc catcccatcg cgcaactggg ccgccttccg cggctggagt ttcacccggc 19620
tcaagaccaa ggaaactcct tccctcggct cgggtttcga cccctacttt gtctactcgg 19680
gctccatccc ctacctcgac gggaccttct acctcaacca caccttcaag aaggtctcca 19740
tcatgttcga ctcctcggtc agctggcccg gcaacgaccg gctgctcacg ccgaacgagt 19800
tcgagatcaa gcgcagcgtc gacggggagg gctacaacgt ggcccaatgc aacatgacca 19860
aggactggtt cctcgtccag atgctctccc actacaacat cggctaccag ggcttccacg 19920
tgcccgaggg ctacaaggac cgcatgtact ccttcttccg caacttccag cccatgagca 19980
ggcaggtggt cgatgagatc aactacaagg actacaaggc cgtcaccctg cccttccagc 20040
acaataactc gggcttcacc ggctacctcg cacccaccat gcgccagggg cagccctacc 20100
ccgccaactt cccctacccg ctcatcggtc agacagccgt gccctccgtc acccagaaaa 20160
agttcctctg cgacagggtc atgtggcgca tccccttctc cagcaacttc atgtccatgg 20220
gcgccctcac cgacctgggt cagaacatgc tctacgccaa ctcggcccac gcgctcgaca 20280
tgaccttcga ggtggacccc atggatgagc ccaccctcct ctatcttctc ttcgaagttt 20340
tcgacgtggt cagagtacac cagccgcacc gcggcgtcat cgaggccgtc tacctgcgca 20400
cgcccttctc cgccggcaac gccaccacct aagcatgagc ggctccagcg aacgagagct 20460
cgcggccatc gtgcgcgacc tgggctgcgg gccctacttt ttgggcaccc acgacaagcg 20520
cttcccgggc tttctcgccg gcgacaagct ggcctgcgcc atcgtcaaca cggccggccg 20580
cgagaccgga ggcgtgcact ggctcgcctt cggctggaac ccgcgctcgc gcacctgcta 20640
catgttcgac ccctttgggt tctcggaccg ccggctcaag cagatttaca gcttcgagta 20700
cgaggccatg ctgcgccgca gcgccctggc ctcctcgccc gaccgctgtc tcagcctcga 20760
gcagtccact cagaccgtgc aggggcccga ctccgccgcc tgcggactct tctgttgcat 20820
gttcttgcat gccttcgtgc actggcccga ccgacccatg gacggaaacc ccaccatgaa 20880
cttgctgacg ggggtgccca acggcatgct acaatcgcca caggtgctgc ccaccctcag 20940
gcgcaaccag gaggaactct accgcttcct cgcgcgccac tccccttact ttcgctccca 21000
ccgcgccgcc atcgaacacg ccaccgcttt tgacaaaatg aaacaactgc gtgtatctca 21060
ataaacagca cttttatttt acatgcactg gagtatatgc aagttattta aaagtcgaag 21120
gggttctcgc gctcgtcgtt gtgcgccgcg ctggggaggg ccacgttgcg gtactggtac 21180
ttgggctgcc acttgaactc ggggatcacc agtttgggca ctggggtctc ggggaaggtc 21240
tcgctccaca tgcgccggct catctgcagg gcgcccagca tgtccggggc ggagatcttg 21300
aaatcgcagt tggggccggt gctctgcgcg cgcgagttgc ggtacacggg gttgcagcac 21360
tggaacacca tcagactggg gtacttcaca ctagccagca cgctcttgtc gctgatctga 21420
tccttgtcca gatcctcggc gttgctcagg ccgaacgggg tcatcttgca cagctggcgt 21480
cccaggaagg gcacgctctg aggcttgtgg ttacactcgc agtgcacggg catcagcatc 21540
atccccgcgc cgcgctgcat attcgggtag agggccttga caaaggccgc gatctgcttg 21600
aaagcttgct gggccttggc cccctcgctg aaaaacaggc cgcagctctt cccgctgaac 21660
tggttattcc cacacccggc atcctgcacg cagcagcgcg cgtcatggct ggtcagttgc 21720
accacgctcc gtccccagcg gttctgggtc accttagcct tgctgggctg ctccttcaac 21780
gcgcgctgcc cgttctcgct ggtcacatcc atctccacca cgtggtcctt gtggatcatc 21840
atcgtcccgt gcagacactt gagctggcct tccacctcgg tgcagccgtg atcccacagg 21900
gcgcaaccgg tgcactccca gttcttgtgc gcaatcccgc tgtggctgaa gatgtaacct 21960
tgcaacatgc ggcccatgat ggtgctaaat gctttctggg tggtgaaggt cagttgcatc 22020
ccgcgggcct cctcgttcat ccaggtctgg cacatcttct ggaagatctc ggtctgctcg 22080
ggcatgagct tgtaagcatc gcgcaggccg ctgtcgacgc ggtagcgttc catcagcacg 22140
ttcatggtat ccatgccctt ctcccaggac gagaccagag gcagactcag agggttgcgt 22200
acgttcagga caccgggggt cgcgggctcg acgatgcgtt ttccgtcctt gccttccttc 22260
aatagaaccg gcggctggct gaatcccact cccacgatca cggcatcttc ctggggcatc 22320
tcttcgtcgg ggtctacctt ggtcacatgc ttggtctttc tggcttgctt cttttttgga 22380
gggctgtcca cggggagcac gtcctcctcg gaagacccgg agcccacccg ctgatacttt 22440
cggcgcttgg tgggcagagg aggtggcggc gaggggctcc tctcctgctc cggcggatag 22500
cgcgccgacc cgtggccccg gggcggagtg gcctctcggc ccatgaaccg gcgcacgtcc 22560
tgactgccgc cggccattgt ttcctagggg aagatggagg agcagccgcg taagcaggag 22620
caggaggagg acttaaccac ccacgagcaa cccaaaatcg agcaggacct gggcttcgaa 22680
gagccggctc gtctagaacc cccacaggat gaacaggagc acgagcaaga cgcaggccag 22740
gaggagaccg acgctgggct cgagcatggc tacctgggag gagaggagga tgtgctgctg 22800
aaacacctgc agcgccagtc cctcatcctc cgggacgccc tggccgaccg gagcgaaacc 22860
cccctcagcg tcgaggagct gtgtcgggcc tacgagctca acctcttctc gccgcgcgta 22920
ccccccaaac gccagcccaa cggcacctgc gagcccaacc cgcgtctcaa cttctatccc 22980
gtctttgcgg tccccgaagc cctcgccacc tatcacatct ttttcaagaa ccaaaagatc 23040
cccgtctcct gccgcgccaa ccgcaccagc gccgacgcgc tcctcgcttt ggggcccggc 23100
gcgcgcatac ctgatatcgc ttccctggaa gaggtgccca agatcttcga agggctcggt 23160
cgggacgaga cgcgcgcggc gaacgctctg aaagaaacag cagaggaaga gggtcacact 23220
agcgccctgg tagagttgga aggcgacaac gccaggctgg ccgtgctcaa gcgcagcgtc 23280
gagcttaccc acttcgccta ccccgccgtc aacctcccgc ccaaggtcat gcgtcgcatc 23340
atggatcagc tcatcatgcc ccacatcgag gccctcgatg aaagtcagga gcagcgcccc 23400
gaggacgccc ggcccgtggt cagcgacgag atgctcgcgc gctggctcgg gacccgcgac 23460
ccccaggctt tggaacagcg gcgcaaactc atgctggccg tggtcctggt cacccttgag 23520
ctcgaatgca tgcgccgctt tttcagcgac cccgagaccc tgcgcaaggt cgaggagacc 23580
ctgcactaca ctttcaggca cggtttcgtc aggcaggcct gcaagatctc caacgtggag 23640
ctgaccaacc tggtctcctg cctggggatc ctgcacgaga accgcctggg ccagaccgtg 23700
ctccactcta ccctgaaggg cgaggcgcgg cgggactatg tccgcgactg cgtctttctc 23760
tttctctgcc acacatggca agcggccatg ggcgtgtggc agcagtgtct cgaggacgag 23820
aacctaaagg agctggacaa gcttcttgct agaaacctta aaaagctgtg gacgggcttc 23880
gacgagcgca ccgtcgcctc ggacctggcc gagatcgtct tccccgagcg cctgagacag 23940
acgctgaaag gcgggctgcc cgacttcatg agccagagca tgttgcaaaa ctaccgcact 24000
ttcattcttg agcgatcagg catcctgccc gccacctgca acgccttccc ctccgacttt 24060
gtaccgctga gctaccgcga gtgtcccccg ccgctgtgga gccactgcta cctcttgcag 24120
ctggccaact acatcgccta ccactcggac gtgatcgagg acgtgagcgg cgaggggctg 24180
ctcgagtgcc actgtcgctg caacctgtgc tccccgcatc gctccctggt ctgcaacccc 24240
cagctcctga gcgagaccca ggtcatcggt accttcgagc tgcaaggtcc gcaggagtcc 24300
accgctccgc tgaaactcac gccggggttg tggacttccg cgtacctgcg caaatttgta 24360
cccgaagact accacgccca tgagataaag ttctttgagg accaatcgcg tccgcagcac 24420
gcggatctca cggcctgcgt catcacccag ggcgcgatcc tcgcccaatt gcacgccatc 24480
caaaaatccc gccaagagtt tcttctgaaa aagggtagag gggtctacct ggacccccag 24540
acgggcgagg tgctcaaccc gggtctcccc cagcatgccg aggaagaagc aggagccgct 24600
agtggaggag atggaagaag aatgggacag ccaggcagag gaggacgaat gggaggagga 24660
gacagaggag gaagaattgg aagaggtgga agaggagcag gcaacagagc agcccgtcgc 24720
cgcaccatcc gcgccggcag ccccgccggt cacggataca acctccgctc cggtcaagcc 24780
tcctcgtaga tgggatcaag tgaagggtga cggtaagcac gagcggcagg gctaccgatc 24840
atggagggcc cacaaagccg cgatcatcgc ctgcttgcaa gactgcgggg ggaacatcgc 24900
tttcgcccgc cgctacctgc tcttccaccg cggggtgaac atcccccgca acgtgttgca 24960
ttactaccgt caccttcaca gctaagaaaa agcaagtcaa aggagtcgcc ggaggaggag 25020
gaggaggcct gaggatcgcg gcgaacgagc ccttgaccac cagggagctg aggaaccgga 25080
tcttccccac tctttatgcc atttttcagc agagtcgagg tcagcagcaa gagctcaaag 25140
taaaaaaccg gtctctgcgc tcgctcaccc gcagttgctt gtaccacaaa aacgaagatc 25200
agctgcagcg cactctcgaa gacgccgagg ctctgttcca caagtactgc gcgctcactc 25260
ttaaagacta aggcgcgccc acccggaaaa aaggcgggaa ttacctcatc gccaccatga 25320
gcaaggagat tcccacccct tacatgtgga gctatcagcc ccaaatgggc ctggccgcgg 25380
gcgcctccca ggactactcc acccgcatga actggctcag tgccggcccc tcgatgatct 25440
cacgggtcaa cggggtccgc agtcatcgaa accagatatt gttggagcag gcggcggtca 25500
cctccacgcc cagggcaaag ctcaacccgc gtaattggcc ctccaccctg gtgtatcagg 25560
aaatccccgg gccgactacc gtactacttc cgcgtgacgc actggccgaa gtccgcatga 25620
ctaactcagg tgtccagctg gccggcggcg cttcccggtg cccgctccgc ccacaatcgg 25680
gtataaaaac cctggtgatc cgaggcagag gcacacagct caacgacgag ttggtgagct 25740
cttcgatcgg tctgcgaccg gacggagtgt tccaactagc cggagccggg agatcctcct 25800
tcactcccaa ccaggcctac ctgaccttgc agagcagctc ttcggagcct cgctccggag 25860
gcatcggaac cctccagttt gtggaggagt ttgtgccctc ggtctacttc aaccccttct 25920
cgggatcgcc aggcctctac ccggacgagt tcataccgaa cttcgacgca gtgagagaag 25980
cggtggacgg ctacgactga atgtcccatg gtgactcggc tgagctcgct cggttgaggc 26040
atctggacca ctgccgccgc ctgcgctgct tcgcccggga gagctgcgga ctcatctact 26100
ttgagtttcc cgaggagcac cccaacggcc ctgcacacgg agtgcggatc accgtagagg 26160
gcaccaccga gtctcacctg gtcaggttct tcacccagca acccttcctg gtcgagcggg 26220
accggggcgc caccacctac accgtctact gcatctgtcc aaccccgaag ttgcatgaga 26280
atttttgttg tactctttgt ggtgagttta ataaaagcta aactcttgca atactctgga 26340
ccttgtcgtc gtcaactcaa cgagaccgtc tacctcacca accagactga ggtaaaactc 26400
acctgcagac cacacaagac ctatatcatc tggttcttcg agaacacctc atttgcagtc 26460
tccaacactc actgcactag tccatgaact gatgttgatt aaaagcccaa aaaccaatca 26520
gccccttccc ccatttcccc atcccccaat tactcataaa aaataaatca ttggaattaa 26580
tcattcaata aagatcactt acttgaaatc tgaaagtatg tctctggtgt agttgttcag 26640
cagcacctcg gtaccctcct cccagctctg gtactccagt ccccggcggg cggcgaactt 26700
cctccacacc ttgaaaggga tgtcaaattc ctggtccaca attttcattg tcttccctct 26760
cagatggcaa agaggctccg ggtggaagat gacttcaacc ccgtctaccc ctatggctac 26820
gcgcggaatc agaatatccc cttcctcact cccccctttg tctcctccga tggattcaaa 26880
aacttccccc ctggggtcct gtcacttaaa ctggctgatc caatcaccat caacaatggg 26940
gatgtctcac ttaaggtggg agggggactt gctgtagagc aacagactgg taacctaagc 27000
gtaaaccctg atgcaccctt gcaagttgca agtgataagc tacagcttgc tctggctcct 27060
ccattcgagg tcagagatgg aaagcttgct ttaaaggcag gtaatggatt aaaagtacta 27120
gataattcca ttactggatt gactggatta ttgaatacac ttgtggtatt aactggaagg 27180
ggaataggaa cggaggaatt aaaaaatgac gatggtgtaa caaacaaagg agtcggcttg 27240
cgtgtaagac ttggagatga cggcgggctg acatttgata aaaagggtga tttagtagcc 27300
tggaataaaa aagatgacag gcgcaccctg tggacaaccc ctgacacatc tccaaattgc 27360
aaaatgagta cagaaaagga ttctaaactt acgttgacac ttacaaagtg tggaagtcag 27420
gttctgggaa atgtatcttt acttgcagtt acaggtgaat atcatcaaat gactgctact 27480
acaaagaagg atgtaaaaat atctttacta tttgatgaga atggaattct attaccatct 27540
tcgtccctta gcaaagatta ttggaattac agaagtgatg attctattgt atctcaaaaa 27600
tataataatg cagttccatt catgccaaac ctgacagctt atccaaaacc aagcgctcaa 27660
aatgcaaaaa actattcaag aactaaaatc ataagtaatg tctacttagg tgctcttacc 27720
taccaacctg taattatcac tattgcattt aatcaggaaa ctgaaaatgg atgtgcttat 27780
tctataacat ttaccttcac ttggcaaaaa gactattctg cccaacagtt tgatgttaca 27840
tcttttacct tctcatatct tacccaagag aacaaagaca aagactaata aaatgttttg 27900
aactgaattt atgaatcttt atttattttt acaccagcac gggtagtcag tttcccacca 27960
ccagcccatt tcacagtgta aacagtcctt tctccccggc tggccttaaa aagcatcata 28020
tcatgggtaa cagacatatt cttaggtgtt atattccaca cggtttcctg tcgagccaaa 28080
cgctcatcag tgatattaat aaactccccg ggcagctcac ttaagttcat gtcgctgtcc 28140
agctgctgag ccacaggctg ctgtccaact tgcggttgct taacgggcgg cgaaggagaa 28200
gtccacgcct acatgggggt agagtcataa tcgtgcatca ggatagggcg gtggtgctgc 28260
agcagcgcgc gaataaactg ctgccgccgc cgctccgtcc tgcaggaata caacatggca 28320
gtggtctcct cagcgatgat tcgcaccgcc cgcagcataa ggcgccttgt cctccgggca 28380
cagcagcgca ccctgatctc acttaaatca gcacagtaac tgcagcacag caccacaata 28440
ttgttcaaaa tcccacagtg caaggcgctg tatccaaagc tcatggcggg gaccacagaa 28500
cccacgtggc catcatacca caagcgcagg tagattaagt ggcgacccct cataaacacg 28560
ctggacataa acattacctc ttttggcatg ttgtaattca ccacctcccg gtaccatata 28620
aacctctgat taaacatggc gccatccacc accatcctaa accagctggc caaaacctgc 28680
ccgccggcta tacactgcag ggaaccggga ctggaacaat gacagtggag agcccaggac 28740
tcgtaaccat ggatcatcat gctcgtcatg atatcaatgt tggcacaaca caggcacacg 28800
tgcatacact tcctcaggat tacaagctcc tcccgcgtta gaaccatatc ccagggaaca 28860
acccattcct gaatcagcgt aaatcccaca ctgcagggaa gacctcgcac gtaactcacg 28920
ttgtgcattg tcaaagtgtt acattcgggc agcagcggat gatcctccag tatggtagcg 28980
cgggtttctg tctcaaaagg aggtagacga tccctactgt acggagtgcg ccgagacaac 29040
cgagatcgtg ttggtcgtag tgtcatgcca aatggaacgc cggacgtagt cattgaaatg 29100
gattctcttg cgtaccttgt cgtacttctg ccagcagaaa gtggctcggg aacagcagat 29160
acctttcctc ctgctgtcct tccgctgctg acgctcagtc atccaactga agtacagcca 29220
ttcccgcagg ttctccagca gctcctgtgc atctgatgaa acaaaagtcc cgtcgatgcg 29280
gattcccctt aaaacatcag ccaggacatt gtaggccatc ccaatccagt taatgcatcc 29340
tgatctatca tgaagaggag gtgggggaag aactggaaga accattttta ttccaagcgg 29400
tctcgaagga cgataaagtg caagtcacgc aggtgacagc gttccccgcc gctgtgctgg 29460
tggaaacaga cagccaggtc aaaacccact ctattttcaa ggtgctcgac tgtggcttcg 29520
agcagtggct ctacgcgtac atccagcata agaatcacat taaaggctgg acctccatcg 29580
atttcatcaa tcatcaggtt acactcattc accatcccca ggtaattctc atttttccag 29640
ccttggatta tttctacaaa ttgttggtgt aagtccactc cgcacatgtg gaaaagttcc 29700
cacagcgccc cctccacttt cataatcagg cagaccttca tattagaaac agatcctgct 29760
gctccaccac ctgcagcgtg ttcaaaacaa caagattcaa tgaggttctg ccctctgccc 29820
tcagctcacg tctcagcgtc agctgcaaaa agtcactcaa gtcctcagcc actacagctg 29880
acaattcaga gccagggcta agcgtgggac tggcaagcgt gagtgagtac tttaatgctc 29940
caaagctagc acccaaaaac tgcatgctgg aataagctct ctttgtgtca ccggtgatgc 30000
cttccaatag gtgagtgata aagcgaggta gtttttcttt aatcatttga gtaatagaaa 30060
agtcctctaa ataagtcact aggaccccag gaaccacaat gtggtagctg acagcgtgtc 30120
gctcaagcat ggttagtaga gatgagagtc tgaaaaacag aaagcatgca ctaaaccaga 30180
gttgccagtc tcactgaagg aaaaatcact ctctccagca gcaaagtgcc cactgggtgg 30240
ccctctcgga catacaaaaa tcgatccgtg tggttaaaga gcagcacagt tagctcctgt 30300
cttctcccag caaagatcac atcggactgg gttagtatgc ccctggaatg gtagtcattc 30360
aaggccataa atctgccttg gtagccatta ggaatcagca cgctcactct caagtgaacc 30420
aaaaccaccc catgcggagg aatgtggaaa gattctgggc aaaaaaaggt atatctattg 30480
ctagtccctt cctggacggg agcaatccct ccagggctat ctatgaaagc atacagagat 30540
tcagccatag ctcagcccgc ttaccagtag acagagagca cagcagtaca agcgccaaca 30600
gcagcgactg actacccact gacccagctc cctatttaaa ggcaccttac actgacgtaa 30660
tgaccaaagg tctaaaaacc ccgccaaaaa aacacacacg ccctgggtgt ttttcgcgaa 30720
aacacttccg cgttctcact tcctcgtatc gatttcgtga ctcaacttcc gggttcccac 30780
gttacgtcac ttctgccctt acatgtaact cagccgtagg gcgccatctt gcccacgtcc 30840
aaaatggctt ccatgtccgg ccacgcctcc gcggcgaccg ttagccgtgc gtcgtgacgt 30900
catttgcatc accgtttctc gtccaatcag cgttggctcc gccccaaaac cgttaaaatt 30960
caaaagctca tttgcatatt aacttttgtt tactttgtgg ggtatattat tgatgatgtt 31020
aattaagcag gccatgctgt ccaggcaggt agatgacgac catcagggac agcttcaagg 31080
ccagcaaaag gccaggaacc gtaaaaaggc cgcgttgctg gcgtttttcc ataggctccg 31140
cccccctgac gagcatcaca aaaatcgacg ctcaagtcag aggtggcgaa acccgacagg 31200
actataaaga taccaggcgt ttccccctgg aagctccctc gtgcgctctc ctgttccgac 31260
cctgccgctt accggatacc tgtccgcctt tctcccttcg ggaagcgtgg cgctttctca 31320
tagctcacgc tgtaggtatc tcagttcggt gtaggtcgtt cgctccaagc tgggctgtgt 31380
gcacgaaccc cccgttcagc ccgaccgctg cgccttatcc ggtaactatc gtcttgagtc 31440
caacccggta agacacgact tatcgccact ggcagcagcc actggtaaca ggattagcag 31500
agcgaggtat gtaggcggtg ctacagagtt cttgaagtgg tggcctaact acggctacac 31560
tagaaggaca gtatttggta tctgcgctct gctgaagcca gttaccttcg gaaaaagagt 31620
tggtagctct tgatccggca aacaaaccac cgctggtagc ggtggttttt ttgtttgcaa 31680
gcagcagatt acgcgcagaa aaaaaggatc tcaagaagat cctttgatct tttctacggg 31740
gtctgacgct cagtggaacg aaaactcacg ttaagggatt ttggtcatga gattatcaaa 31800
aaggatcttc acctagatcc ttttaaatta aaaatgaagt tttaaatcaa tctaaagtat 31860
atatgagtaa acttggtctg acagttacca atgcttaatc agtgaggcac ctatctcagc 31920
gatctgtcta tttcgttcat ccatagttgc ctgactcccc gtcgtgtaga taactacgat 31980
acgggagggc ttaccatctg gccccagtgc tgcaatgata ccgcgagacc cacgctcacc 32040
ggctccagat ttatcagcaa taaaccagcc agccggaagg gccgagcgca gaagtggtcc 32100
tgcaacttta tccgcctcca tccagtctat taattgttgc cgggaagcta gagtaagtag 32160
ttcgccagtt aatagtttgc gcaacgttgt tgccattgct gcaggcatcg tggtgtcacg 32220
ctcgtcgttt ggtatggctt cattcagctc cggttcccaa cgatcaaggc gagttacatg 32280
atcccccatg ttgtgcaaaa aagcggttag ctccttcggt cctccgatcg ttgtcagaag 32340
taagttggcc gcagtgttat cactcatggt tatggcagca ctgcataatt ctcttactgt 32400
catgccatcc gtaagatgct tttctgtgac tggtgagtac tcaaccaagt cattctgaga 32460
atagtgtatg cggcgaccga gttgctcttg cccggcgtca acacgggata ataccgcgcc 32520
acatagcaga actttaaaag tgctcatcat tggaaaacgt tcttcggggc gaaaactctc 32580
aaggatctta ccgctgttga gatccagttc gatgtaaccc actcgtgcac ccaactgatc 32640
ttcagcatct tttactttca ccagcgtttc tgggtgagca aaaacaggaa ggcaaaatgc 32700
cgcaaaaaag ggaataaggg cgacacggaa atgttgaata ctcatactct tcctttttca 32760
atattattga agcatttatc agggttattg tctcatgagc ggatacatat ttgaatgtat 32820
ttagaaaaat aaacaaatag gggttccgcg cacatttccc cgaaaagtgc cacctgacgt 32880
ctaagaaacc attattatca tgacattaac ctataaaaat aggcgtatca cgaggccctt 32940
tcgtcttcaa gaattggtcg atggcaaaca gctattatgg gtattatggg ttcgaattaa 33000
ttaatcga 33008
<210> 18
<211> 33002
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVR35.luc
<400> 18
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat gcatctcaat ggattgcaaa aggcgtacca actgcagcag 18000
ccgcaggcaa tggtgaagaa gaacatgaaa cagaggagaa aactgctact tacacttttg 18060
ccaatgctcc tgtaaaagcc gaggctcaaa ttacaaaaga gggcttacca ataggtttgg 18120
agatttcagc tgaaaacgaa tctaaaccca tctatgcaga taaaactttc cagccagaac 18180
ctcaagtggg agatgaaact tggactgacc tagacggaaa aaccgaagag tatggaggca 18240
gggctctaaa gcctgacact aaaatgaaac catgctatgg atcttttgct agacctacta 18300
atgagaaagg aggtcaggca aagttcaaac cagttaatga aggagaacaa cctaaagatc 18360
tggatataga tatggaattt tttgataact catcgcaaag aacaaacttc agtcctaaaa 18420
ttgtcatgta cactgaaaat gttaatcttg aaacaccaga cactcatgtg gtttacaagc 18480
ctggaacaga agacacaagt tccgaagcta atttgggaca gcagtccatg ccaaacagac 18540
ccaactacat tggctttagg gacaactttg taggtctcat gtattacaac agcaccggaa 18600
atatgggtgt gctggctggt caggcttctc agttgaacgc tgtggtcgac ttgcaagaca 18660
gaaacaccga gttatcttac cagctattgc tagattctct gggtgacaga accagatact 18720
ttagcatgtg gaactctgcg gtggacagtt acgatccaga tgtcaggatc attgaaaatc 18780
acggtgtgga agatgaactt ccaaactatt gcttcccatt ggacggcata ggtgttccaa 18840
caaccagtta caaatcaata gttccaaatg gagaagataa taataattgg aaagaacctg 18900
aagtaaatgg aacaagtgag atcggacagg gtaatttgtt tgccatggag atcaacctgc 18960
aggccaacct gtggaagagt tttctgtact cgaacgtggc cctgtacctg cccgactcct 19020
acaagtacac gccggccaac gtcaagctgc ccgccaacac caacacctac gagtacatga 19080
acggccgcgt ggtagccccc tcgctggtgg acgcctacat caacatcggc gcccgctggt 19140
cgttggatcc catggacaac gtcaacccct tcaaccacca ccgcaatgcg ggcctgcgct 19200
accgctccat gctgctgggc aacggccgct acgtgccctt ccacatccaa gtgccccaaa 19260
agttctttgc catcaagaac ctgctcctgc tcccgggctc ctacacctac gagtggaact 19320
tccgcaagga cgtcaacatg atcctgcaga gttccctcgg caacgacctg cgcgtcgacg 19380
gcgcctccgt ccgcttcgac agcgtcaacc tatacgccac tttcttcccc atggcgcaca 19440
acaccgcttc aaccttggaa gccatgctgc gcaacgacac caacgaccag tccttcaacg 19500
actacctctc ggccgccaac atgctctacc ccatcccggc caaggccacc aacgtgccca 19560
tctccatccc atcgcgcaac tgggccgcct tccgcggctg gagtttcacc cggctcaaga 19620
ccaaggaaac tccttccctc ggctcgggtt tcgaccccta ctttgtctac tcgggctcca 19680
tcccctacct cgacgggacc ttctacctca accacacctt caagaaggtc tccatcatgt 19740
tcgactcctc ggtcagctgg cccggcaacg accggctgct cacgccgaac gagttcgaga 19800
tcaagcgcag cgtcgacggg gagggctaca acgtggccca atgcaacatg accaaggact 19860
ggttcctcgt ccagatgctc tcccactaca acatcggcta ccagggcttc cacgtgcccg 19920
agggctacaa ggaccgcatg tactccttct tccgcaactt ccagcccatg agcaggcagg 19980
tggtcgatga gatcaactac aaggactaca aggccgtcac cctgcccttc cagcacaata 20040
actcgggctt caccggctac ctcgcaccca ccatgcgcca ggggcagccc taccccgcca 20100
acttccccta cccgctcatc ggtcagacag ccgtgccctc cgtcacccag aaaaagttcc 20160
tctgcgacag ggtcatgtgg cgcatcccct tctccagcaa cttcatgtcc atgggcgccc 20220
tcaccgacct gggtcagaac atgctctacg ccaactcggc ccacgcgctc gacatgacct 20280
tcgaggtgga ccccatggat gagcccaccc tcctctatct tctcttcgaa gttttcgacg 20340
tggtcagagt acaccagccg caccgcggcg tcatcgaggc cgtctacctg cgcacgccct 20400
tctccgccgg caacgccacc acctaagcat gagcggctcc agcgaacgag agctcgcggc 20460
catcgtgcgc gacctgggct gcgggcccta ctttttgggc acccacgaca agcgcttccc 20520
gggctttctc gccggcgaca agctggcctg cgccatcgtc aacacggccg gccgcgagac 20580
cggaggcgtg cactggctcg ccttcggctg gaacccgcgc tcgcgcacct gctacatgtt 20640
cgaccccttt gggttctcgg accgccggct caagcagatt tacagcttcg agtacgaggc 20700
catgctgcgc cgcagcgccc tggcctcctc gcccgaccgc tgtctcagcc tcgagcagtc 20760
cactcagacc gtgcaggggc ccgactccgc cgcctgcgga ctcttctgtt gcatgttctt 20820
gcatgccttc gtgcactggc ccgaccgacc catggacgga aaccccacca tgaacttgct 20880
gacgggggtg cccaacggca tgctacaatc gccacaggtg ctgcccaccc tcaggcgcaa 20940
ccaggaggaa ctctaccgct tcctcgcgcg ccactcccct tactttcgct cccaccgcgc 21000
cgccatcgaa cacgccaccg cttttgacaa aatgaaacaa ctgcgtgtat ctcaataaac 21060
agcactttta ttttacatgc actggagtat atgcaagtta tttaaaagtc gaaggggttc 21120
tcgcgctcgt cgttgtgcgc cgcgctgggg agggccacgt tgcggtactg gtacttgggc 21180
tgccacttga actcggggat caccagtttg ggcactgggg tctcggggaa ggtctcgctc 21240
cacatgcgcc ggctcatctg cagggcgccc agcatgtccg gggcggagat cttgaaatcg 21300
cagttggggc cggtgctctg cgcgcgcgag ttgcggtaca cggggttgca gcactggaac 21360
accatcagac tggggtactt cacactagcc agcacgctct tgtcgctgat ctgatccttg 21420
tccagatcct cggcgttgct caggccgaac ggggtcatct tgcacagctg gcgtcccagg 21480
aagggcacgc tctgaggctt gtggttacac tcgcagtgca cgggcatcag catcatcccc 21540
gcgccgcgct gcatattcgg gtagagggcc ttgacaaagg ccgcgatctg cttgaaagct 21600
tgctgggcct tggccccctc gctgaaaaac aggccgcagc tcttcccgct gaactggtta 21660
ttcccacacc cggcatcctg cacgcagcag cgcgcgtcat ggctggtcag ttgcaccacg 21720
ctccgtcccc agcggttctg ggtcacctta gccttgctgg gctgctcctt caacgcgcgc 21780
tgcccgttct cgctggtcac atccatctcc accacgtggt ccttgtggat catcatcgtc 21840
ccgtgcagac acttgagctg gccttccacc tcggtgcagc cgtgatccca cagggcgcaa 21900
ccggtgcact cccagttctt gtgcgcaatc ccgctgtggc tgaagatgta accttgcaac 21960
atgcggccca tgatggtgct aaatgctttc tgggtggtga aggtcagttg catcccgcgg 22020
gcctcctcgt tcatccaggt ctggcacatc ttctggaaga tctcggtctg ctcgggcatg 22080
agcttgtaag catcgcgcag gccgctgtcg acgcggtagc gttccatcag cacgttcatg 22140
gtatccatgc ccttctccca ggacgagacc agaggcagac tcagagggtt gcgtacgttc 22200
aggacaccgg gggtcgcggg ctcgacgatg cgttttccgt ccttgccttc cttcaataga 22260
accggcggct ggctgaatcc cactcccacg atcacggcat cttcctgggg catctcttcg 22320
tcggggtcta ccttggtcac atgcttggtc tttctggctt gcttcttttt tggagggctg 22380
tccacgggga gcacgtcctc ctcggaagac ccggagccca cccgctgata ctttcggcgc 22440
ttggtgggca gaggaggtgg cggcgagggg ctcctctcct gctccggcgg atagcgcgcc 22500
gacccgtggc cccggggcgg agtggcctct cggcccatga accggcgcac gtcctgactg 22560
ccgccggcca ttgtttccta ggggaagatg gaggagcagc cgcgtaagca ggagcaggag 22620
gaggacttaa ccacccacga gcaacccaaa atcgagcagg acctgggctt cgaagagccg 22680
gctcgtctag aacccccaca ggatgaacag gagcacgagc aagacgcagg ccaggaggag 22740
accgacgctg ggctcgagca tggctacctg ggaggagagg aggatgtgct gctgaaacac 22800
ctgcagcgcc agtccctcat cctccgggac gccctggccg accggagcga aacccccctc 22860
agcgtcgagg agctgtgtcg ggcctacgag ctcaacctct tctcgccgcg cgtacccccc 22920
aaacgccagc ccaacggcac ctgcgagccc aacccgcgtc tcaacttcta tcccgtcttt 22980
gcggtccccg aagccctcgc cacctatcac atctttttca agaaccaaaa gatccccgtc 23040
tcctgccgcg ccaaccgcac cagcgccgac gcgctcctcg ctttggggcc cggcgcgcgc 23100
atacctgata tcgcttccct ggaagaggtg cccaagatct tcgaagggct cggtcgggac 23160
gagacgcgcg cggcgaacgc tctgaaagaa acagcagagg aagagggtca cactagcgcc 23220
ctggtagagt tggaaggcga caacgccagg ctggccgtgc tcaagcgcag cgtcgagctt 23280
acccacttcg cctaccccgc cgtcaacctc ccgcccaagg tcatgcgtcg catcatggat 23340
cagctcatca tgccccacat cgaggccctc gatgaaagtc aggagcagcg ccccgaggac 23400
gcccggcccg tggtcagcga cgagatgctc gcgcgctggc tcgggacccg cgacccccag 23460
gctttggaac agcggcgcaa actcatgctg gccgtggtcc tggtcaccct tgagctcgaa 23520
tgcatgcgcc gctttttcag cgaccccgag accctgcgca aggtcgagga gaccctgcac 23580
tacactttca ggcacggttt cgtcaggcag gcctgcaaga tctccaacgt ggagctgacc 23640
aacctggtct cctgcctggg gatcctgcac gagaaccgcc tgggccagac cgtgctccac 23700
tctaccctga agggcgaggc gcggcgggac tatgtccgcg actgcgtctt tctctttctc 23760
tgccacacat ggcaagcggc catgggcgtg tggcagcagt gtctcgagga cgagaaccta 23820
aaggagctgg acaagcttct tgctagaaac cttaaaaagc tgtggacggg cttcgacgag 23880
cgcaccgtcg cctcggacct ggccgagatc gtcttccccg agcgcctgag acagacgctg 23940
aaaggcgggc tgcccgactt catgagccag agcatgttgc aaaactaccg cactttcatt 24000
cttgagcgat caggcatcct gcccgccacc tgcaacgcct tcccctccga ctttgtaccg 24060
ctgagctacc gcgagtgtcc cccgccgctg tggagccact gctacctctt gcagctggcc 24120
aactacatcg cctaccactc ggacgtgatc gaggacgtga gcggcgaggg gctgctcgag 24180
tgccactgtc gctgcaacct gtgctccccg catcgctccc tggtctgcaa cccccagctc 24240
ctgagcgaga cccaggtcat cggtaccttc gagctgcaag gtccgcagga gtccaccgct 24300
ccgctgaaac tcacgccggg gttgtggact tccgcgtacc tgcgcaaatt tgtacccgaa 24360
gactaccacg cccatgagat aaagttcttt gaggaccaat cgcgtccgca gcacgcggat 24420
ctcacggcct gcgtcatcac ccagggcgcg atcctcgccc aattgcacgc catccaaaaa 24480
tcccgccaag agtttcttct gaaaaagggt agaggggtct acctggaccc ccagacgggc 24540
gaggtgctca acccgggtct cccccagcat gccgaggaag aagcaggagc cgctagtgga 24600
ggagatggaa gaagaatggg acagccaggc agaggaggac gaatgggagg aggagacaga 24660
ggaggaagaa ttggaagagg tggaagagga gcaggcaaca gagcagcccg tcgccgcacc 24720
atccgcgccg gcagccccgc cggtcacgga tacaacctcc gctccggtca agcctcctcg 24780
tagatgggat caagtgaagg gtgacggtaa gcacgagcgg cagggctacc gatcatggag 24840
ggcccacaaa gccgcgatca tcgcctgctt gcaagactgc ggggggaaca tcgctttcgc 24900
ccgccgctac ctgctcttcc accgcggggt gaacatcccc cgcaacgtgt tgcattacta 24960
ccgtcacctt cacagctaag aaaaagcaag tcaaaggagt cgccggagga ggaggaggag 25020
gcctgaggat cgcggcgaac gagcccttga ccaccaggga gctgaggaac cggatcttcc 25080
ccactcttta tgccattttt cagcagagtc gaggtcagca gcaagagctc aaagtaaaaa 25140
accggtctct gcgctcgctc acccgcagtt gcttgtacca caaaaacgaa gatcagctgc 25200
agcgcactct cgaagacgcc gaggctctgt tccacaagta ctgcgcgctc actcttaaag 25260
actaaggcgc gcccacccgg aaaaaaggcg ggaattacct catcgccacc atgagcaagg 25320
agattcccac cccttacatg tggagctatc agccccaaat gggcctggcc gcgggcgcct 25380
cccaggacta ctccacccgc atgaactggc tcagtgccgg cccctcgatg atctcacggg 25440
tcaacggggt ccgcagtcat cgaaaccaga tattgttgga gcaggcggcg gtcacctcca 25500
cgcccagggc aaagctcaac ccgcgtaatt ggccctccac cctggtgtat caggaaatcc 25560
ccgggccgac taccgtacta cttccgcgtg acgcactggc cgaagtccgc atgactaact 25620
caggtgtcca gctggccggc ggcgcttccc ggtgcccgct ccgcccacaa tcgggtataa 25680
aaaccctggt gatccgaggc agaggcacac agctcaacga cgagttggtg agctcttcga 25740
tcggtctgcg accggacgga gtgttccaac tagccggagc cgggagatcc tccttcactc 25800
ccaaccaggc ctacctgacc ttgcagagca gctcttcgga gcctcgctcc ggaggcatcg 25860
gaaccctcca gtttgtggag gagtttgtgc cctcggtcta cttcaacccc ttctcgggat 25920
cgccaggcct ctacccggac gagttcatac cgaacttcga cgcagtgaga gaagcggtgg 25980
acggctacga ctgaatgtcc catggtgact cggctgagct cgctcggttg aggcatctgg 26040
accactgccg ccgcctgcgc tgcttcgccc gggagagctg cggactcatc tactttgagt 26100
ttcccgagga gcaccccaac ggccctgcac acggagtgcg gatcaccgta gagggcacca 26160
ccgagtctca cctggtcagg ttcttcaccc agcaaccctt cctggtcgag cgggaccggg 26220
gcgccaccac ctacaccgtc tactgcatct gtccaacccc gaagttgcat gagaattttt 26280
gttgtactct ttgtggtgag tttaataaaa gctaaactct tgcaatactc tggaccttgt 26340
cgtcgtcaac tcaacgagac cgtctacctc accaaccaga ctgaggtaaa actcacctgc 26400
agaccacaca agacctatat catctggttc ttcgagaaca cctcatttgc agtctccaac 26460
actcactgca ctagtccatg aactgatgtt gattaaaagc ccaaaaacca atcagcccct 26520
tcccccattt ccccatcccc caattactca taaaaaataa atcattggaa ttaatcattc 26580
aataaagatc acttacttga aatctgaaag tatgtctctg gtgtagttgt tcagcagcac 26640
ctcggtaccc tcctcccagc tctggtactc cagtccccgg cgggcggcga acttcctcca 26700
caccttgaaa gggatgtcaa attcctggtc cacaattttc attgtcttcc ctctcagatg 26760
gcaaagaggc tccgggtgga agatgacttc aaccccgtct acccctatgg ctacgcgcgg 26820
aatcagaata tccccttcct cactcccccc tttgtctcct ccgatggatt caaaaacttc 26880
ccccctgggg tcctgtcact taaactggct gatccaatca ccatcaacaa tggggatgtc 26940
tcacttaagg tgggaggggg acttgctgta gagcaacaga ctggtaacct aagcgtaaac 27000
cctgatgcac ccttgcaagt tgcaagtgat aagctacagc ttgctctggc tcctccattc 27060
gaggtcagag atggaaagct tgctttaaag gcaggtaatg gattaaaagt actagataat 27120
tccattactg gattgactgg attattgaat acacttgtgg tattaactgg aaggggaata 27180
ggaacggagg aattaaaaaa tgacgatggt gtaacaaaca aaggagtcgg cttgcgtgta 27240
agacttggag atgacggcgg gctgacattt gataaaaagg gtgatttagt agcctggaat 27300
aaaaaagatg acaggcgcac cctgtggaca acccctgaca catctccaaa ttgcaaaatg 27360
agtacagaaa aggattctaa acttacgttg acacttacaa agtgtggaag tcaggttctg 27420
ggaaatgtat ctttacttgc agttacaggt gaatatcatc aaatgactgc tactacaaag 27480
aaggatgtaa aaatatcttt actatttgat gagaatggaa ttctattacc atcttcgtcc 27540
cttagcaaag attattggaa ttacagaagt gatgattcta ttgtatctca aaaatataat 27600
aatgcagttc cattcatgcc aaacctgaca gcttatccaa aaccaagcgc tcaaaatgca 27660
aaaaactatt caagaactaa aatcataagt aatgtctact taggtgctct tacctaccaa 27720
cctgtaatta tcactattgc atttaatcag gaaactgaaa atggatgtgc ttattctata 27780
acatttacct tcacttggca aaaagactat tctgcccaac agtttgatgt tacatctttt 27840
accttctcat atcttaccca agagaacaaa gacaaagact aataaaatgt tttgaactga 27900
atttatgaat ctttatttat ttttacacca gcacgggtag tcagtttccc accaccagcc 27960
catttcacag tgtaaacagt cctttctccc cggctggcct taaaaagcat catatcatgg 28020
gtaacagaca tattcttagg tgttatattc cacacggttt cctgtcgagc caaacgctca 28080
tcagtgatat taataaactc cccgggcagc tcacttaagt tcatgtcgct gtccagctgc 28140
tgagccacag gctgctgtcc aacttgcggt tgcttaacgg gcggcgaagg agaagtccac 28200
gcctacatgg gggtagagtc ataatcgtgc atcaggatag ggcggtggtg ctgcagcagc 28260
gcgcgaataa actgctgccg ccgccgctcc gtcctgcagg aatacaacat ggcagtggtc 28320
tcctcagcga tgattcgcac cgcccgcagc ataaggcgcc ttgtcctccg ggcacagcag 28380
cgcaccctga tctcacttaa atcagcacag taactgcagc acagcaccac aatattgttc 28440
aaaatcccac agtgcaaggc gctgtatcca aagctcatgg cggggaccac agaacccacg 28500
tggccatcat accacaagcg caggtagatt aagtggcgac ccctcataaa cacgctggac 28560
ataaacatta cctcttttgg catgttgtaa ttcaccacct cccggtacca tataaacctc 28620
tgattaaaca tggcgccatc caccaccatc ctaaaccagc tggccaaaac ctgcccgccg 28680
gctatacact gcagggaacc gggactggaa caatgacagt ggagagccca ggactcgtaa 28740
ccatggatca tcatgctcgt catgatatca atgttggcac aacacaggca cacgtgcata 28800
cacttcctca ggattacaag ctcctcccgc gttagaacca tatcccaggg aacaacccat 28860
tcctgaatca gcgtaaatcc cacactgcag ggaagacctc gcacgtaact cacgttgtgc 28920
attgtcaaag tgttacattc gggcagcagc ggatgatcct ccagtatggt agcgcgggtt 28980
tctgtctcaa aaggaggtag acgatcccta ctgtacggag tgcgccgaga caaccgagat 29040
cgtgttggtc gtagtgtcat gccaaatgga acgccggacg tagtcattga aatggattct 29100
cttgcgtacc ttgtcgtact tctgccagca gaaagtggct cgggaacagc agataccttt 29160
cctcctgctg tccttccgct gctgacgctc agtcatccaa ctgaagtaca gccattcccg 29220
caggttctcc agcagctcct gtgcatctga tgaaacaaaa gtcccgtcga tgcggattcc 29280
ccttaaaaca tcagccagga cattgtaggc catcccaatc cagttaatgc atcctgatct 29340
atcatgaaga ggaggtgggg gaagaactgg aagaaccatt tttattccaa gcggtctcga 29400
aggacgataa agtgcaagtc acgcaggtga cagcgttccc cgccgctgtg ctggtggaaa 29460
cagacagcca ggtcaaaacc cactctattt tcaaggtgct cgactgtggc ttcgagcagt 29520
ggctctacgc gtacatccag cataagaatc acattaaagg ctggacctcc atcgatttca 29580
tcaatcatca ggttacactc attcaccatc cccaggtaat tctcattttt ccagccttgg 29640
attatttcta caaattgttg gtgtaagtcc actccgcaca tgtggaaaag ttcccacagc 29700
gccccctcca ctttcataat caggcagacc ttcatattag aaacagatcc tgctgctcca 29760
ccacctgcag cgtgttcaaa acaacaagat tcaatgaggt tctgccctct gccctcagct 29820
cacgtctcag cgtcagctgc aaaaagtcac tcaagtcctc agccactaca gctgacaatt 29880
cagagccagg gctaagcgtg ggactggcaa gcgtgagtga gtactttaat gctccaaagc 29940
tagcacccaa aaactgcatg ctggaataag ctctctttgt gtcaccggtg atgccttcca 30000
ataggtgagt gataaagcga ggtagttttt ctttaatcat ttgagtaata gaaaagtcct 30060
ctaaataagt cactaggacc ccaggaacca caatgtggta gctgacagcg tgtcgctcaa 30120
gcatggttag tagagatgag agtctgaaaa acagaaagca tgcactaaac cagagttgcc 30180
agtctcactg aaggaaaaat cactctctcc agcagcaaag tgcccactgg gtggccctct 30240
cggacataca aaaatcgatc cgtgtggtta aagagcagca cagttagctc ctgtcttctc 30300
ccagcaaaga tcacatcgga ctgggttagt atgcccctgg aatggtagtc attcaaggcc 30360
ataaatctgc cttggtagcc attaggaatc agcacgctca ctctcaagtg aaccaaaacc 30420
accccatgcg gaggaatgtg gaaagattct gggcaaaaaa aggtatatct attgctagtc 30480
ccttcctgga cgggagcaat ccctccaggg ctatctatga aagcatacag agattcagcc 30540
atagctcagc ccgcttacca gtagacagag agcacagcag tacaagcgcc aacagcagcg 30600
actgactacc cactgaccca gctccctatt taaaggcacc ttacactgac gtaatgacca 30660
aaggtctaaa aaccccgcca aaaaaacaca cacgccctgg gtgtttttcg cgaaaacact 30720
tccgcgttct cacttcctcg tatcgatttc gtgactcaac ttccgggttc ccacgttacg 30780
tcacttctgc ccttacatgt aactcagccg tagggcgcca tcttgcccac gtccaaaatg 30840
gcttccatgt ccggccacgc ctccgcggcg accgttagcc gtgcgtcgtg acgtcatttg 30900
catcaccgtt tctcgtccaa tcagcgttgg ctccgcccca aaaccgttaa aattcaaaag 30960
ctcatttgca tattaacttt tgtttacttt gtggggtata ttattgatga tgttaattaa 31020
gcaggccatg ctgtccaggc aggtagatga cgaccatcag ggacagcttc aaggccagca 31080
aaaggccagg aaccgtaaaa aggccgcgtt gctggcgttt ttccataggc tccgcccccc 31140
tgacgagcat cacaaaaatc gacgctcaag tcagaggtgg cgaaacccga caggactata 31200
aagataccag gcgtttcccc ctggaagctc cctcgtgcgc tctcctgttc cgaccctgcc 31260
gcttaccgga tacctgtccg cctttctccc ttcgggaagc gtggcgcttt ctcatagctc 31320
acgctgtagg tatctcagtt cggtgtaggt cgttcgctcc aagctgggct gtgtgcacga 31380
accccccgtt cagcccgacc gctgcgcctt atccggtaac tatcgtcttg agtccaaccc 31440
ggtaagacac gacttatcgc cactggcagc agccactggt aacaggatta gcagagcgag 31500
gtatgtaggc ggtgctacag agttcttgaa gtggtggcct aactacggct acactagaag 31560
gacagtattt ggtatctgcg ctctgctgaa gccagttacc ttcggaaaaa gagttggtag 31620
ctcttgatcc ggcaaacaaa ccaccgctgg tagcggtggt ttttttgttt gcaagcagca 31680
gattacgcgc agaaaaaaag gatctcaaga agatcctttg atcttttcta cggggtctga 31740
cgctcagtgg aacgaaaact cacgttaagg gattttggtc atgagattat caaaaaggat 31800
cttcacctag atccttttaa attaaaaatg aagttttaaa tcaatctaaa gtatatatga 31860
gtaaacttgg tctgacagtt accaatgctt aatcagtgag gcacctatct cagcgatctg 31920
tctatttcgt tcatccatag ttgcctgact ccccgtcgtg tagataacta cgatacggga 31980
gggcttacca tctggcccca gtgctgcaat gataccgcga gacccacgct caccggctcc 32040
agatttatca gcaataaacc agccagccgg aagggccgag cgcagaagtg gtcctgcaac 32100
tttatccgcc tccatccagt ctattaattg ttgccgggaa gctagagtaa gtagttcgcc 32160
agttaatagt ttgcgcaacg ttgttgccat tgctgcaggc atcgtggtgt cacgctcgtc 32220
gtttggtatg gcttcattca gctccggttc ccaacgatca aggcgagtta catgatcccc 32280
catgttgtgc aaaaaagcgg ttagctcctt cggtcctccg atcgttgtca gaagtaagtt 32340
ggccgcagtg ttatcactca tggttatggc agcactgcat aattctctta ctgtcatgcc 32400
atccgtaaga tgcttttctg tgactggtga gtactcaacc aagtcattct gagaatagtg 32460
tatgcggcga ccgagttgct cttgcccggc gtcaacacgg gataataccg cgccacatag 32520
cagaacttta aaagtgctca tcattggaaa acgttcttcg gggcgaaaac tctcaaggat 32580
cttaccgctg ttgagatcca gttcgatgta acccactcgt gcacccaact gatcttcagc 32640
atcttttact ttcaccagcg tttctgggtg agcaaaaaca ggaaggcaaa atgccgcaaa 32700
aaagggaata agggcgacac ggaaatgttg aatactcata ctcttccttt ttcaatatta 32760
ttgaagcatt tatcagggtt attgtctcat gagcggatac atatttgaat gtatttagaa 32820
aaataaacaa ataggggttc cgcgcacatt tccccgaaaa gtgccacctg acgtctaaga 32880
aaccattatt atcatgacat taacctataa aaataggcgt atcacgaggc cctttcgtct 32940
tcaagaattg gtcgatggca aacagctatt atgggtatta tgggttcgaa ttaattaatc 33000
ga 33002
<210> 19
<211> 32933
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVR52.luc
<400> 19
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat tccgtagagt ggccggataa tactaaaaca aaagtgagag 18000
cccaagcacc gtttgtaagc gacgaaatca ctaaagacgg cataaaggtt ggaacagata 18060
ccgcaaccac ccaacaaagc atttacgccg ataaaacttt ccagccagaa cctcaagtag 18120
gggaaacaca gtggaacagc gatgtaggca ctaatgataa agtggcagga agagttttaa 18180
agaaagacac taaaatgaaa ccatgctatg gatcttttgc tagacctact aatgagaaag 18240
gaggtcaggc aaagttcaaa ccagttaatg aaggagaaca acctaaagat ctggatatag 18300
atatgcagtt ttttgccacc actgcagcca atacaacacc aaaagctgtt ctttacactg 18360
aaaatgttaa tcttgaaaca ccagacactc atgtggttta caagcccact gtgacagagg 18420
gaacgacaag tgccgaagct ttgctagcgc agcagtccat gccaaacaga cccaactaca 18480
ttggctttag ggacaacttt gtaggtctca tgtattacaa cagcaccgga aatatgggtg 18540
tgctggctgg tcaggcttct cagttgaacg ctgtggtcga cttgcaagac agaaacaccg 18600
agttatctta ccagctattg ctagattctc tgggtgacag aaccagatac tttagcatgt 18660
ggaactctgc ggtggacagt tacgatccag atgtcaggat cattgaaaat cacggtgtgg 18720
aagatgaact tccaaactat tgcttcccat tgggaggaat ggcggtcaca gacacctact 18780
cccccataaa atccaataat ggaagcggtt ggcaagtaga caacgatacg tttgccgaca 18840
ggggggtgga aataggctcg ggaaacatgt tcgccatgga gatcaacctg caggccaacc 18900
tgtggaagag ttttctgtac tcgaacgtgg ccctgtacct gcccgactcc tacaagtaca 18960
cgccggccaa cgtcaagctg cccgccaaca ccaacaccta cgagtacatg aacggccgcg 19020
tggtagcccc ctcgctggtg gacgcctaca tcaacatcgg cgcccgctgg tcgttggatc 19080
ccatggacaa cgtcaacccc ttcaaccacc accgcaatgc gggcctgcgc taccgctcca 19140
tgctgctggg caacggccgc tacgtgccct tccacatcca agtgccccaa aagttctttg 19200
ccatcaagaa cctgctcctg ctcccgggct cctacaccta cgagtggaac ttccgcaagg 19260
acgtcaacat gatcctgcag agttccctcg gcaacgacct gcgcgtcgac ggcgcctccg 19320
tccgcttcga cagcgtcaac ctatacgcca ctttcttccc catggcgcac aacaccgctt 19380
caaccttgga agccatgctg cgcaacgaca ccaacgacca gtccttcaac gactacctct 19440
cggccgccaa catgctctac cccatcccgg ccaaggccac caacgtgccc atctccatcc 19500
catcgcgcaa ctgggccgcc ttccgcggct ggagtttcac ccggctcaag accaaggaaa 19560
ctccttccct cggctcgggt ttcgacccct actttgtcta ctcgggctcc atcccctacc 19620
tcgacgggac cttctacctc aaccacacct tcaagaaggt ctccatcatg ttcgactcct 19680
cggtcagctg gcccggcaac gaccggctgc tcacgccgaa cgagttcgag atcaagcgca 19740
gcgtcgacgg ggagggctac aacgtggccc aatgcaacat gaccaaggac tggttcctcg 19800
tccagatgct ctcccactac aacatcggct accagggctt ccacgtgccc gagggctaca 19860
aggaccgcat gtactccttc ttccgcaact tccagcccat gagcaggcag gtggtcgatg 19920
agatcaacta caaggactac aaggccgtca ccctgccctt ccagcacaat aactcgggct 19980
tcaccggcta cctcgcaccc accatgcgcc aggggcagcc ctaccccgcc aacttcccct 20040
acccgctcat cggtcagaca gccgtgccct ccgtcaccca gaaaaagttc ctctgcgaca 20100
gggtcatgtg gcgcatcccc ttctccagca acttcatgtc catgggcgcc ctcaccgacc 20160
tgggtcagaa catgctctac gccaactcgg cccacgcgct cgacatgacc ttcgaggtgg 20220
accccatgga tgagcccacc ctcctctatc ttctcttcga agttttcgac gtggtcagag 20280
tacaccagcc gcaccgcggc gtcatcgagg ccgtctacct gcgcacgccc ttctccgccg 20340
gcaacgccac cacctaagca tgagcggctc cagcgaacga gagctcgcgg ccatcgtgcg 20400
cgacctgggc tgcgggccct actttttggg cacccacgac aagcgcttcc cgggctttct 20460
cgccggcgac aagctggcct gcgccatcgt caacacggcc ggccgcgaga ccggaggcgt 20520
gcactggctc gccttcggct ggaacccgcg ctcgcgcacc tgctacatgt tcgacccctt 20580
tgggttctcg gaccgccggc tcaagcagat ttacagcttc gagtacgagg ccatgctgcg 20640
ccgcagcgcc ctggcctcct cgcccgaccg ctgtctcagc ctcgagcagt ccactcagac 20700
cgtgcagggg cccgactccg ccgcctgcgg actcttctgt tgcatgttct tgcatgcctt 20760
cgtgcactgg cccgaccgac ccatggacgg aaaccccacc atgaacttgc tgacgggggt 20820
gcccaacggc atgctacaat cgccacaggt gctgcccacc ctcaggcgca accaggagga 20880
actctaccgc ttcctcgcgc gccactcccc ttactttcgc tcccaccgcg ccgccatcga 20940
acacgccacc gcttttgaca aaatgaaaca actgcgtgta tctcaataaa cagcactttt 21000
attttacatg cactggagta tatgcaagtt atttaaaagt cgaaggggtt ctcgcgctcg 21060
tcgttgtgcg ccgcgctggg gagggccacg ttgcggtact ggtacttggg ctgccacttg 21120
aactcgggga tcaccagttt gggcactggg gtctcgggga aggtctcgct ccacatgcgc 21180
cggctcatct gcagggcgcc cagcatgtcc ggggcggaga tcttgaaatc gcagttgggg 21240
ccggtgctct gcgcgcgcga gttgcggtac acggggttgc agcactggaa caccatcaga 21300
ctggggtact tcacactagc cagcacgctc ttgtcgctga tctgatcctt gtccagatcc 21360
tcggcgttgc tcaggccgaa cggggtcatc ttgcacagct ggcgtcccag gaagggcacg 21420
ctctgaggct tgtggttaca ctcgcagtgc acgggcatca gcatcatccc cgcgccgcgc 21480
tgcatattcg ggtagagggc cttgacaaag gccgcgatct gcttgaaagc ttgctgggcc 21540
ttggccccct cgctgaaaaa caggccgcag ctcttcccgc tgaactggtt attcccacac 21600
ccggcatcct gcacgcagca gcgcgcgtca tggctggtca gttgcaccac gctccgtccc 21660
cagcggttct gggtcacctt agccttgctg ggctgctcct tcaacgcgcg ctgcccgttc 21720
tcgctggtca catccatctc caccacgtgg tccttgtgga tcatcatcgt cccgtgcaga 21780
cacttgagct ggccttccac ctcggtgcag ccgtgatccc acagggcgca accggtgcac 21840
tcccagttct tgtgcgcaat cccgctgtgg ctgaagatgt aaccttgcaa catgcggccc 21900
atgatggtgc taaatgcttt ctgggtggtg aaggtcagtt gcatcccgcg ggcctcctcg 21960
ttcatccagg tctggcacat cttctggaag atctcggtct gctcgggcat gagcttgtaa 22020
gcatcgcgca ggccgctgtc gacgcggtag cgttccatca gcacgttcat ggtatccatg 22080
cccttctccc aggacgagac cagaggcaga ctcagagggt tgcgtacgtt caggacaccg 22140
ggggtcgcgg gctcgacgat gcgttttccg tccttgcctt ccttcaatag aaccggcggc 22200
tggctgaatc ccactcccac gatcacggca tcttcctggg gcatctcttc gtcggggtct 22260
accttggtca catgcttggt ctttctggct tgcttctttt ttggagggct gtccacgggg 22320
agcacgtcct cctcggaaga cccggagccc acccgctgat actttcggcg cttggtgggc 22380
agaggaggtg gcggcgaggg gctcctctcc tgctccggcg gatagcgcgc cgacccgtgg 22440
ccccggggcg gagtggcctc tcggcccatg aaccggcgca cgtcctgact gccgccggcc 22500
attgtttcct aggggaagat ggaggagcag ccgcgtaagc aggagcagga ggaggactta 22560
accacccacg agcaacccaa aatcgagcag gacctgggct tcgaagagcc ggctcgtcta 22620
gaacccccac aggatgaaca ggagcacgag caagacgcag gccaggagga gaccgacgct 22680
gggctcgagc atggctacct gggaggagag gaggatgtgc tgctgaaaca cctgcagcgc 22740
cagtccctca tcctccggga cgccctggcc gaccggagcg aaacccccct cagcgtcgag 22800
gagctgtgtc gggcctacga gctcaacctc ttctcgccgc gcgtaccccc caaacgccag 22860
cccaacggca cctgcgagcc caacccgcgt ctcaacttct atcccgtctt tgcggtcccc 22920
gaagccctcg ccacctatca catctttttc aagaaccaaa agatccccgt ctcctgccgc 22980
gccaaccgca ccagcgccga cgcgctcctc gctttggggc ccggcgcgcg catacctgat 23040
atcgcttccc tggaagaggt gcccaagatc ttcgaagggc tcggtcggga cgagacgcgc 23100
gcggcgaacg ctctgaaaga aacagcagag gaagagggtc acactagcgc cctggtagag 23160
ttggaaggcg acaacgccag gctggccgtg ctcaagcgca gcgtcgagct tacccacttc 23220
gcctaccccg ccgtcaacct cccgcccaag gtcatgcgtc gcatcatgga tcagctcatc 23280
atgccccaca tcgaggccct cgatgaaagt caggagcagc gccccgagga cgcccggccc 23340
gtggtcagcg acgagatgct cgcgcgctgg ctcgggaccc gcgaccccca ggctttggaa 23400
cagcggcgca aactcatgct ggccgtggtc ctggtcaccc ttgagctcga atgcatgcgc 23460
cgctttttca gcgaccccga gaccctgcgc aaggtcgagg agaccctgca ctacactttc 23520
aggcacggtt tcgtcaggca ggcctgcaag atctccaacg tggagctgac caacctggtc 23580
tcctgcctgg ggatcctgca cgagaaccgc ctgggccaga ccgtgctcca ctctaccctg 23640
aagggcgagg cgcggcggga ctatgtccgc gactgcgtct ttctctttct ctgccacaca 23700
tggcaagcgg ccatgggcgt gtggcagcag tgtctcgagg acgagaacct aaaggagctg 23760
gacaagcttc ttgctagaaa ccttaaaaag ctgtggacgg gcttcgacga gcgcaccgtc 23820
gcctcggacc tggccgagat cgtcttcccc gagcgcctga gacagacgct gaaaggcggg 23880
ctgcccgact tcatgagcca gagcatgttg caaaactacc gcactttcat tcttgagcga 23940
tcaggcatcc tgcccgccac ctgcaacgcc ttcccctccg actttgtacc gctgagctac 24000
cgcgagtgtc ccccgccgct gtggagccac tgctacctct tgcagctggc caactacatc 24060
gcctaccact cggacgtgat cgaggacgtg agcggcgagg ggctgctcga gtgccactgt 24120
cgctgcaacc tgtgctcccc gcatcgctcc ctggtctgca acccccagct cctgagcgag 24180
acccaggtca tcggtacctt cgagctgcaa ggtccgcagg agtccaccgc tccgctgaaa 24240
ctcacgccgg ggttgtggac ttccgcgtac ctgcgcaaat ttgtacccga agactaccac 24300
gcccatgaga taaagttctt tgaggaccaa tcgcgtccgc agcacgcgga tctcacggcc 24360
tgcgtcatca cccagggcgc gatcctcgcc caattgcacg ccatccaaaa atcccgccaa 24420
gagtttcttc tgaaaaaggg tagaggggtc tacctggacc cccagacggg cgaggtgctc 24480
aacccgggtc tcccccagca tgccgaggaa gaagcaggag ccgctagtgg aggagatgga 24540
agaagaatgg gacagccagg cagaggagga cgaatgggag gaggagacag aggaggaaga 24600
attggaagag gtggaagagg agcaggcaac agagcagccc gtcgccgcac catccgcgcc 24660
ggcagccccg ccggtcacgg atacaacctc cgctccggtc aagcctcctc gtagatggga 24720
tcaagtgaag ggtgacggta agcacgagcg gcagggctac cgatcatgga gggcccacaa 24780
agccgcgatc atcgcctgct tgcaagactg cggggggaac atcgctttcg cccgccgcta 24840
cctgctcttc caccgcgggg tgaacatccc ccgcaacgtg ttgcattact accgtcacct 24900
tcacagctaa gaaaaagcaa gtcaaaggag tcgccggagg aggaggagga ggcctgagga 24960
tcgcggcgaa cgagcccttg accaccaggg agctgaggaa ccggatcttc cccactcttt 25020
atgccatttt tcagcagagt cgaggtcagc agcaagagct caaagtaaaa aaccggtctc 25080
tgcgctcgct cacccgcagt tgcttgtacc acaaaaacga agatcagctg cagcgcactc 25140
tcgaagacgc cgaggctctg ttccacaagt actgcgcgct cactcttaaa gactaaggcg 25200
cgcccacccg gaaaaaaggc gggaattacc tcatcgccac catgagcaag gagattccca 25260
ccccttacat gtggagctat cagccccaaa tgggcctggc cgcgggcgcc tcccaggact 25320
actccacccg catgaactgg ctcagtgccg gcccctcgat gatctcacgg gtcaacgggg 25380
tccgcagtca tcgaaaccag atattgttgg agcaggcggc ggtcacctcc acgcccaggg 25440
caaagctcaa cccgcgtaat tggccctcca ccctggtgta tcaggaaatc cccgggccga 25500
ctaccgtact acttccgcgt gacgcactgg ccgaagtccg catgactaac tcaggtgtcc 25560
agctggccgg cggcgcttcc cggtgcccgc tccgcccaca atcgggtata aaaaccctgg 25620
tgatccgagg cagaggcaca cagctcaacg acgagttggt gagctcttcg atcggtctgc 25680
gaccggacgg agtgttccaa ctagccggag ccgggagatc ctccttcact cccaaccagg 25740
cctacctgac cttgcagagc agctcttcgg agcctcgctc cggaggcatc ggaaccctcc 25800
agtttgtgga ggagtttgtg ccctcggtct acttcaaccc cttctcggga tcgccaggcc 25860
tctacccgga cgagttcata ccgaacttcg acgcagtgag agaagcggtg gacggctacg 25920
actgaatgtc ccatggtgac tcggctgagc tcgctcggtt gaggcatctg gaccactgcc 25980
gccgcctgcg ctgcttcgcc cgggagagct gcggactcat ctactttgag tttcccgagg 26040
agcaccccaa cggccctgca cacggagtgc ggatcaccgt agagggcacc accgagtctc 26100
acctggtcag gttcttcacc cagcaaccct tcctggtcga gcgggaccgg ggcgccacca 26160
cctacaccgt ctactgcatc tgtccaaccc cgaagttgca tgagaatttt tgttgtactc 26220
tttgtggtga gtttaataaa agctaaactc ttgcaatact ctggaccttg tcgtcgtcaa 26280
ctcaacgaga ccgtctacct caccaaccag actgaggtaa aactcacctg cagaccacac 26340
aagacctata tcatctggtt cttcgagaac acctcatttg cagtctccaa cactcactgc 26400
actagtccat gaactgatgt tgattaaaag cccaaaaacc aatcagcccc ttcccccatt 26460
tccccatccc ccaattactc ataaaaaata aatcattgga attaatcatt caataaagat 26520
cacttacttg aaatctgaaa gtatgtctct ggtgtagttg ttcagcagca cctcggtacc 26580
ctcctcccag ctctggtact ccagtccccg gcgggcggcg aacttcctcc acaccttgaa 26640
agggatgtca aattcctggt ccacaatttt cattgtcttc cctctcagat ggcaaagagg 26700
ctccgggtgg aagatgactt caaccccgtc tacccctatg gctacgcgcg gaatcagaat 26760
atccccttcc tcactccccc ctttgtctcc tccgatggat tcaaaaactt cccccctggg 26820
gtcctgtcac ttaaactggc tgatccaatc accatcaaca atggggatgt ctcacttaag 26880
gtgggagggg gacttgctgt agagcaacag actggtaacc taagcgtaaa ccctgatgca 26940
cccttgcaag ttgcaagtga taagctacag cttgctctgg ctcctccatt cgaggtcaga 27000
gatggaaagc ttgctttaaa ggcaggtaat ggattaaaag tactagataa ttccattact 27060
ggattgactg gattattgaa tacacttgtg gtattaactg gaaggggaat aggaacggag 27120
gaattaaaaa atgacgatgg tgtaacaaac aaaggagtcg gcttgcgtgt aagacttgga 27180
gatgacggcg ggctgacatt tgataaaaag ggtgatttag tagcctggaa taaaaaagat 27240
gacaggcgca ccctgtggac aacccctgac acatctccaa attgcaaaat gagtacagaa 27300
aaggattcta aacttacgtt gacacttaca aagtgtggaa gtcaggttct gggaaatgta 27360
tctttacttg cagttacagg tgaatatcat caaatgactg ctactacaaa gaaggatgta 27420
aaaatatctt tactatttga tgagaatgga attctattac catcttcgtc ccttagcaaa 27480
gattattgga attacagaag tgatgattct attgtatctc aaaaatataa taatgcagtt 27540
ccattcatgc caaacctgac agcttatcca aaaccaagcg ctcaaaatgc aaaaaactat 27600
tcaagaacta aaatcataag taatgtctac ttaggtgctc ttacctacca acctgtaatt 27660
atcactattg catttaatca ggaaactgaa aatggatgtg cttattctat aacatttacc 27720
ttcacttggc aaaaagacta ttctgcccaa cagtttgatg ttacatcttt taccttctca 27780
tatcttaccc aagagaacaa agacaaagac taataaaatg ttttgaactg aatttatgaa 27840
tctttattta tttttacacc agcacgggta gtcagtttcc caccaccagc ccatttcaca 27900
gtgtaaacag tcctttctcc ccggctggcc ttaaaaagca tcatatcatg ggtaacagac 27960
atattcttag gtgttatatt ccacacggtt tcctgtcgag ccaaacgctc atcagtgata 28020
ttaataaact ccccgggcag ctcacttaag ttcatgtcgc tgtccagctg ctgagccaca 28080
ggctgctgtc caacttgcgg ttgcttaacg ggcggcgaag gagaagtcca cgcctacatg 28140
ggggtagagt cataatcgtg catcaggata gggcggtggt gctgcagcag cgcgcgaata 28200
aactgctgcc gccgccgctc cgtcctgcag gaatacaaca tggcagtggt ctcctcagcg 28260
atgattcgca ccgcccgcag cataaggcgc cttgtcctcc gggcacagca gcgcaccctg 28320
atctcactta aatcagcaca gtaactgcag cacagcacca caatattgtt caaaatccca 28380
cagtgcaagg cgctgtatcc aaagctcatg gcggggacca cagaacccac gtggccatca 28440
taccacaagc gcaggtagat taagtggcga cccctcataa acacgctgga cataaacatt 28500
acctcttttg gcatgttgta attcaccacc tcccggtacc atataaacct ctgattaaac 28560
atggcgccat ccaccaccat cctaaaccag ctggccaaaa cctgcccgcc ggctatacac 28620
tgcagggaac cgggactgga acaatgacag tggagagccc aggactcgta accatggatc 28680
atcatgctcg tcatgatatc aatgttggca caacacaggc acacgtgcat acacttcctc 28740
aggattacaa gctcctcccg cgttagaacc atatcccagg gaacaaccca ttcctgaatc 28800
agcgtaaatc ccacactgca gggaagacct cgcacgtaac tcacgttgtg cattgtcaaa 28860
gtgttacatt cgggcagcag cggatgatcc tccagtatgg tagcgcgggt ttctgtctca 28920
aaaggaggta gacgatccct actgtacgga gtgcgccgag acaaccgaga tcgtgttggt 28980
cgtagtgtca tgccaaatgg aacgccggac gtagtcattg aaatggattc tcttgcgtac 29040
cttgtcgtac ttctgccagc agaaagtggc tcgggaacag cagatacctt tcctcctgct 29100
gtccttccgc tgctgacgct cagtcatcca actgaagtac agccattccc gcaggttctc 29160
cagcagctcc tgtgcatctg atgaaacaaa agtcccgtcg atgcggattc cccttaaaac 29220
atcagccagg acattgtagg ccatcccaat ccagttaatg catcctgatc tatcatgaag 29280
aggaggtggg ggaagaactg gaagaaccat ttttattcca agcggtctcg aaggacgata 29340
aagtgcaagt cacgcaggtg acagcgttcc ccgccgctgt gctggtggaa acagacagcc 29400
aggtcaaaac ccactctatt ttcaaggtgc tcgactgtgg cttcgagcag tggctctacg 29460
cgtacatcca gcataagaat cacattaaag gctggacctc catcgatttc atcaatcatc 29520
aggttacact cattcaccat ccccaggtaa ttctcatttt tccagccttg gattatttct 29580
acaaattgtt ggtgtaagtc cactccgcac atgtggaaaa gttcccacag cgccccctcc 29640
actttcataa tcaggcagac cttcatatta gaaacagatc ctgctgctcc accacctgca 29700
gcgtgttcaa aacaacaaga ttcaatgagg ttctgccctc tgccctcagc tcacgtctca 29760
gcgtcagctg caaaaagtca ctcaagtcct cagccactac agctgacaat tcagagccag 29820
ggctaagcgt gggactggca agcgtgagtg agtactttaa tgctccaaag ctagcaccca 29880
aaaactgcat gctggaataa gctctctttg tgtcaccggt gatgccttcc aataggtgag 29940
tgataaagcg aggtagtttt tctttaatca tttgagtaat agaaaagtcc tctaaataag 30000
tcactaggac cccaggaacc acaatgtggt agctgacagc gtgtcgctca agcatggtta 30060
gtagagatga gagtctgaaa aacagaaagc atgcactaaa ccagagttgc cagtctcact 30120
gaaggaaaaa tcactctctc cagcagcaaa gtgcccactg ggtggccctc tcggacatac 30180
aaaaatcgat ccgtgtggtt aaagagcagc acagttagct cctgtcttct cccagcaaag 30240
atcacatcgg actgggttag tatgcccctg gaatggtagt cattcaaggc cataaatctg 30300
ccttggtagc cattaggaat cagcacgctc actctcaagt gaaccaaaac caccccatgc 30360
ggaggaatgt ggaaagattc tgggcaaaaa aaggtatatc tattgctagt cccttcctgg 30420
acgggagcaa tccctccagg gctatctatg aaagcataca gagattcagc catagctcag 30480
cccgcttacc agtagacaga gagcacagca gtacaagcgc caacagcagc gactgactac 30540
ccactgaccc agctccctat ttaaaggcac cttacactga cgtaatgacc aaaggtctaa 30600
aaaccccgcc aaaaaaacac acacgccctg ggtgtttttc gcgaaaacac ttccgcgttc 30660
tcacttcctc gtatcgattt cgtgactcaa cttccgggtt cccacgttac gtcacttctg 30720
cccttacatg taactcagcc gtagggcgcc atcttgccca cgtccaaaat ggcttccatg 30780
tccggccacg cctccgcggc gaccgttagc cgtgcgtcgt gacgtcattt gcatcaccgt 30840
ttctcgtcca atcagcgttg gctccgcccc aaaaccgtta aaattcaaaa gctcatttgc 30900
atattaactt ttgtttactt tgtggggtat attattgatg atgttaatta agcaggccat 30960
gctgtccagg caggtagatg acgaccatca gggacagctt caaggccagc aaaaggccag 31020
gaaccgtaaa aaggccgcgt tgctggcgtt tttccatagg ctccgccccc ctgacgagca 31080
tcacaaaaat cgacgctcaa gtcagaggtg gcgaaacccg acaggactat aaagatacca 31140
ggcgtttccc cctggaagct ccctcgtgcg ctctcctgtt ccgaccctgc cgcttaccgg 31200
atacctgtcc gcctttctcc cttcgggaag cgtggcgctt tctcatagct cacgctgtag 31260
gtatctcagt tcggtgtagg tcgttcgctc caagctgggc tgtgtgcacg aaccccccgt 31320
tcagcccgac cgctgcgcct tatccggtaa ctatcgtctt gagtccaacc cggtaagaca 31380
cgacttatcg ccactggcag cagccactgg taacaggatt agcagagcga ggtatgtagg 31440
cggtgctaca gagttcttga agtggtggcc taactacggc tacactagaa ggacagtatt 31500
tggtatctgc gctctgctga agccagttac cttcggaaaa agagttggta gctcttgatc 31560
cggcaaacaa accaccgctg gtagcggtgg tttttttgtt tgcaagcagc agattacgcg 31620
cagaaaaaaa ggatctcaag aagatccttt gatcttttct acggggtctg acgctcagtg 31680
gaacgaaaac tcacgttaag ggattttggt catgagatta tcaaaaagga tcttcaccta 31740
gatcctttta aattaaaaat gaagttttaa atcaatctaa agtatatatg agtaaacttg 31800
gtctgacagt taccaatgct taatcagtga ggcacctatc tcagcgatct gtctatttcg 31860
ttcatccata gttgcctgac tccccgtcgt gtagataact acgatacggg agggcttacc 31920
atctggcccc agtgctgcaa tgataccgcg agacccacgc tcaccggctc cagatttatc 31980
agcaataaac cagccagccg gaagggccga gcgcagaagt ggtcctgcaa ctttatccgc 32040
ctccatccag tctattaatt gttgccggga agctagagta agtagttcgc cagttaatag 32100
tttgcgcaac gttgttgcca ttgctgcagg catcgtggtg tcacgctcgt cgtttggtat 32160
ggcttcattc agctccggtt cccaacgatc aaggcgagtt acatgatccc ccatgttgtg 32220
caaaaaagcg gttagctcct tcggtcctcc gatcgttgtc agaagtaagt tggccgcagt 32280
gttatcactc atggttatgg cagcactgca taattctctt actgtcatgc catccgtaag 32340
atgcttttct gtgactggtg agtactcaac caagtcattc tgagaatagt gtatgcggcg 32400
accgagttgc tcttgcccgg cgtcaacacg ggataatacc gcgccacata gcagaacttt 32460
aaaagtgctc atcattggaa aacgttcttc ggggcgaaaa ctctcaagga tcttaccgct 32520
gttgagatcc agttcgatgt aacccactcg tgcacccaac tgatcttcag catcttttac 32580
tttcaccagc gtttctgggt gagcaaaaac aggaaggcaa aatgccgcaa aaaagggaat 32640
aagggcgaca cggaaatgtt gaatactcat actcttcctt tttcaatatt attgaagcat 32700
ttatcagggt tattgtctca tgagcggata catatttgaa tgtatttaga aaaataaaca 32760
aataggggtt ccgcgcacat ttccccgaaa agtgccacct gacgtctaag aaaccattat 32820
tatcatgaca ttaacctata aaaataggcg tatcacgagg ccctttcgtc ttcaagaatt 32880
ggtcgatggc aaacagctat tatgggtatt atgggttcga attaattaat cga 32933
<210> 20
<211> 32954
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVRPtr1.luc
<400> 20
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat ccaagtcaat gggaagaaac ttccacagat gctactacta 18000
ctactactca cagctttggc ctggctgcta tgaaggggga caatattaca tctgacggtt 18060
tgcagatagg aacagatgct acttctggag aggaaaaacc catctatgca gataaaactt 18120
tccagccaga acctcaaata ggggaagagt catggactga tactgacgga accaatgaaa 18180
aattcggagg aagagtcctt aaaaaggaca ctaaaatgaa accatgctat ggatcttttg 18240
ctagacctac taatgagaaa ggaggtcagg caaagttcaa accagttaat gaaggagaac 18300
aacctaaaga tctggatata gatatgaact tttttgatgg tagagatgca gctgctaact 18360
ttactccaga agtagtgttg tacactgaaa atgttaatct tgaaacacca gacactcatg 18420
tggtttacaa gccaggaacc tcagatgtga gttcccatgt caatttgggt cagcagtcca 18480
tgccaaacag acccaactac attggcttta gggacaactt tgtaggtctc atgtattaca 18540
acagcaccgg aaatatgggt gtgctggctg gtcaggcttc tcagttgaac gctgtggtcg 18600
acttgcaaga cagaaacacc gagttatctt accagctatt gctagattct ctgggtgaca 18660
gaaccagata ctttagcatg tggaactctg cggtggacag ttacgatcca gatgtcagga 18720
tcattgaaaa tcacggtgtg gaagatgaac ttccaaacta ttgcttccca ttggacgctg 18780
tgggtattac taaaacttat caaggtatca aaacgcaaaa tggtcaaact acaacgtggg 18840
aaaaggacac cagtgttagt acggccaatg aaataggcat tggcaacaat cttgccatgg 18900
agatcaacct gcaggccaac ctgtggaaga gttttctgta ctcgaacgtg gccctgtacc 18960
tgcccgactc ctacaagtac acgccggcca acgtcaagct gcccgccaac accaacacct 19020
acgagtacat gaacggccgc gtggtagccc cctcgctggt ggacgcctac atcaacatcg 19080
gcgcccgctg gtcgttggat cccatggaca acgtcaaccc cttcaaccac caccgcaatg 19140
cgggcctgcg ctaccgctcc atgctgctgg gcaacggccg ctacgtgccc ttccacatcc 19200
aagtgcccca aaagttcttt gccatcaaga acctgctcct gctcccgggc tcctacacct 19260
acgagtggaa cttccgcaag gacgtcaaca tgatcctgca gagttccctc ggcaacgacc 19320
tgcgcgtcga cggcgcctcc gtccgcttcg acagcgtcaa cctatacgcc actttcttcc 19380
ccatggcgca caacaccgct tcaaccttgg aagccatgct gcgcaacgac accaacgacc 19440
agtccttcaa cgactacctc tcggccgcca acatgctcta ccccatcccg gccaaggcca 19500
ccaacgtgcc catctccatc ccatcgcgca actgggccgc cttccgcggc tggagtttca 19560
cccggctcaa gaccaaggaa actccttccc tcggctcggg tttcgacccc tactttgtct 19620
actcgggctc catcccctac ctcgacggga ccttctacct caaccacacc ttcaagaagg 19680
tctccatcat gttcgactcc tcggtcagct ggcccggcaa cgaccggctg ctcacgccga 19740
acgagttcga gatcaagcgc agcgtcgacg gggagggcta caacgtggcc caatgcaaca 19800
tgaccaagga ctggttcctc gtccagatgc tctcccacta caacatcggc taccagggct 19860
tccacgtgcc cgagggctac aaggaccgca tgtactcctt cttccgcaac ttccagccca 19920
tgagcaggca ggtggtcgat gagatcaact acaaggacta caaggccgtc accctgccct 19980
tccagcacaa taactcgggc ttcaccggct acctcgcacc caccatgcgc caggggcagc 20040
cctaccccgc caacttcccc tacccgctca tcggtcagac agccgtgccc tccgtcaccc 20100
agaaaaagtt cctctgcgac agggtcatgt ggcgcatccc cttctccagc aacttcatgt 20160
ccatgggcgc cctcaccgac ctgggtcaga acatgctcta cgccaactcg gcccacgcgc 20220
tcgacatgac cttcgaggtg gaccccatgg atgagcccac cctcctctat cttctcttcg 20280
aagttttcga cgtggtcaga gtacaccagc cgcaccgcgg cgtcatcgag gccgtctacc 20340
tgcgcacgcc cttctccgcc ggcaacgcca ccacctaagc atgagcggct ccagcgaacg 20400
agagctcgcg gccatcgtgc gcgacctggg ctgcgggccc tactttttgg gcacccacga 20460
caagcgcttc ccgggctttc tcgccggcga caagctggcc tgcgccatcg tcaacacggc 20520
cggccgcgag accggaggcg tgcactggct cgccttcggc tggaacccgc gctcgcgcac 20580
ctgctacatg ttcgacccct ttgggttctc ggaccgccgg ctcaagcaga tttacagctt 20640
cgagtacgag gccatgctgc gccgcagcgc cctggcctcc tcgcccgacc gctgtctcag 20700
cctcgagcag tccactcaga ccgtgcaggg gcccgactcc gccgcctgcg gactcttctg 20760
ttgcatgttc ttgcatgcct tcgtgcactg gcccgaccga cccatggacg gaaaccccac 20820
catgaacttg ctgacggggg tgcccaacgg catgctacaa tcgccacagg tgctgcccac 20880
cctcaggcgc aaccaggagg aactctaccg cttcctcgcg cgccactccc cttactttcg 20940
ctcccaccgc gccgccatcg aacacgccac cgcttttgac aaaatgaaac aactgcgtgt 21000
atctcaataa acagcacttt tattttacat gcactggagt atatgcaagt tatttaaaag 21060
tcgaaggggt tctcgcgctc gtcgttgtgc gccgcgctgg ggagggccac gttgcggtac 21120
tggtacttgg gctgccactt gaactcgggg atcaccagtt tgggcactgg ggtctcgggg 21180
aaggtctcgc tccacatgcg ccggctcatc tgcagggcgc ccagcatgtc cggggcggag 21240
atcttgaaat cgcagttggg gccggtgctc tgcgcgcgcg agttgcggta cacggggttg 21300
cagcactgga acaccatcag actggggtac ttcacactag ccagcacgct cttgtcgctg 21360
atctgatcct tgtccagatc ctcggcgttg ctcaggccga acggggtcat cttgcacagc 21420
tggcgtccca ggaagggcac gctctgaggc ttgtggttac actcgcagtg cacgggcatc 21480
agcatcatcc ccgcgccgcg ctgcatattc gggtagaggg ccttgacaaa ggccgcgatc 21540
tgcttgaaag cttgctgggc cttggccccc tcgctgaaaa acaggccgca gctcttcccg 21600
ctgaactggt tattcccaca cccggcatcc tgcacgcagc agcgcgcgtc atggctggtc 21660
agttgcacca cgctccgtcc ccagcggttc tgggtcacct tagccttgct gggctgctcc 21720
ttcaacgcgc gctgcccgtt ctcgctggtc acatccatct ccaccacgtg gtccttgtgg 21780
atcatcatcg tcccgtgcag acacttgagc tggccttcca cctcggtgca gccgtgatcc 21840
cacagggcgc aaccggtgca ctcccagttc ttgtgcgcaa tcccgctgtg gctgaagatg 21900
taaccttgca acatgcggcc catgatggtg ctaaatgctt tctgggtggt gaaggtcagt 21960
tgcatcccgc gggcctcctc gttcatccag gtctggcaca tcttctggaa gatctcggtc 22020
tgctcgggca tgagcttgta agcatcgcgc aggccgctgt cgacgcggta gcgttccatc 22080
agcacgttca tggtatccat gcccttctcc caggacgaga ccagaggcag actcagaggg 22140
ttgcgtacgt tcaggacacc gggggtcgcg ggctcgacga tgcgttttcc gtccttgcct 22200
tccttcaata gaaccggcgg ctggctgaat cccactccca cgatcacggc atcttcctgg 22260
ggcatctctt cgtcggggtc taccttggtc acatgcttgg tctttctggc ttgcttcttt 22320
tttggagggc tgtccacggg gagcacgtcc tcctcggaag acccggagcc cacccgctga 22380
tactttcggc gcttggtggg cagaggaggt ggcggcgagg ggctcctctc ctgctccggc 22440
ggatagcgcg ccgacccgtg gccccggggc ggagtggcct ctcggcccat gaaccggcgc 22500
acgtcctgac tgccgccggc cattgtttcc taggggaaga tggaggagca gccgcgtaag 22560
caggagcagg aggaggactt aaccacccac gagcaaccca aaatcgagca ggacctgggc 22620
ttcgaagagc cggctcgtct agaaccccca caggatgaac aggagcacga gcaagacgca 22680
ggccaggagg agaccgacgc tgggctcgag catggctacc tgggaggaga ggaggatgtg 22740
ctgctgaaac acctgcagcg ccagtccctc atcctccggg acgccctggc cgaccggagc 22800
gaaacccccc tcagcgtcga ggagctgtgt cgggcctacg agctcaacct cttctcgccg 22860
cgcgtacccc ccaaacgcca gcccaacggc acctgcgagc ccaacccgcg tctcaacttc 22920
tatcccgtct ttgcggtccc cgaagccctc gccacctatc acatcttttt caagaaccaa 22980
aagatccccg tctcctgccg cgccaaccgc accagcgccg acgcgctcct cgctttgggg 23040
cccggcgcgc gcatacctga tatcgcttcc ctggaagagg tgcccaagat cttcgaaggg 23100
ctcggtcggg acgagacgcg cgcggcgaac gctctgaaag aaacagcaga ggaagagggt 23160
cacactagcg ccctggtaga gttggaaggc gacaacgcca ggctggccgt gctcaagcgc 23220
agcgtcgagc ttacccactt cgcctacccc gccgtcaacc tcccgcccaa ggtcatgcgt 23280
cgcatcatgg atcagctcat catgccccac atcgaggccc tcgatgaaag tcaggagcag 23340
cgccccgagg acgcccggcc cgtggtcagc gacgagatgc tcgcgcgctg gctcgggacc 23400
cgcgaccccc aggctttgga acagcggcgc aaactcatgc tggccgtggt cctggtcacc 23460
cttgagctcg aatgcatgcg ccgctttttc agcgaccccg agaccctgcg caaggtcgag 23520
gagaccctgc actacacttt caggcacggt ttcgtcaggc aggcctgcaa gatctccaac 23580
gtggagctga ccaacctggt ctcctgcctg gggatcctgc acgagaaccg cctgggccag 23640
accgtgctcc actctaccct gaagggcgag gcgcggcggg actatgtccg cgactgcgtc 23700
tttctctttc tctgccacac atggcaagcg gccatgggcg tgtggcagca gtgtctcgag 23760
gacgagaacc taaaggagct ggacaagctt cttgctagaa accttaaaaa gctgtggacg 23820
ggcttcgacg agcgcaccgt cgcctcggac ctggccgaga tcgtcttccc cgagcgcctg 23880
agacagacgc tgaaaggcgg gctgcccgac ttcatgagcc agagcatgtt gcaaaactac 23940
cgcactttca ttcttgagcg atcaggcatc ctgcccgcca cctgcaacgc cttcccctcc 24000
gactttgtac cgctgagcta ccgcgagtgt cccccgccgc tgtggagcca ctgctacctc 24060
ttgcagctgg ccaactacat cgcctaccac tcggacgtga tcgaggacgt gagcggcgag 24120
gggctgctcg agtgccactg tcgctgcaac ctgtgctccc cgcatcgctc cctggtctgc 24180
aacccccagc tcctgagcga gacccaggtc atcggtacct tcgagctgca aggtccgcag 24240
gagtccaccg ctccgctgaa actcacgccg gggttgtgga cttccgcgta cctgcgcaaa 24300
tttgtacccg aagactacca cgcccatgag ataaagttct ttgaggacca atcgcgtccg 24360
cagcacgcgg atctcacggc ctgcgtcatc acccagggcg cgatcctcgc ccaattgcac 24420
gccatccaaa aatcccgcca agagtttctt ctgaaaaagg gtagaggggt ctacctggac 24480
ccccagacgg gcgaggtgct caacccgggt ctcccccagc atgccgagga agaagcagga 24540
gccgctagtg gaggagatgg aagaagaatg ggacagccag gcagaggagg acgaatggga 24600
ggaggagaca gaggaggaag aattggaaga ggtggaagag gagcaggcaa cagagcagcc 24660
cgtcgccgca ccatccgcgc cggcagcccc gccggtcacg gatacaacct ccgctccggt 24720
caagcctcct cgtagatggg atcaagtgaa gggtgacggt aagcacgagc ggcagggcta 24780
ccgatcatgg agggcccaca aagccgcgat catcgcctgc ttgcaagact gcggggggaa 24840
catcgctttc gcccgccgct acctgctctt ccaccgcggg gtgaacatcc cccgcaacgt 24900
gttgcattac taccgtcacc ttcacagcta agaaaaagca agtcaaagga gtcgccggag 24960
gaggaggagg aggcctgagg atcgcggcga acgagccctt gaccaccagg gagctgagga 25020
accggatctt ccccactctt tatgccattt ttcagcagag tcgaggtcag cagcaagagc 25080
tcaaagtaaa aaaccggtct ctgcgctcgc tcacccgcag ttgcttgtac cacaaaaacg 25140
aagatcagct gcagcgcact ctcgaagacg ccgaggctct gttccacaag tactgcgcgc 25200
tcactcttaa agactaaggc gcgcccaccc ggaaaaaagg cgggaattac ctcatcgcca 25260
ccatgagcaa ggagattccc accccttaca tgtggagcta tcagccccaa atgggcctgg 25320
ccgcgggcgc ctcccaggac tactccaccc gcatgaactg gctcagtgcc ggcccctcga 25380
tgatctcacg ggtcaacggg gtccgcagtc atcgaaacca gatattgttg gagcaggcgg 25440
cggtcacctc cacgcccagg gcaaagctca acccgcgtaa ttggccctcc accctggtgt 25500
atcaggaaat ccccgggccg actaccgtac tacttccgcg tgacgcactg gccgaagtcc 25560
gcatgactaa ctcaggtgtc cagctggccg gcggcgcttc ccggtgcccg ctccgcccac 25620
aatcgggtat aaaaaccctg gtgatccgag gcagaggcac acagctcaac gacgagttgg 25680
tgagctcttc gatcggtctg cgaccggacg gagtgttcca actagccgga gccgggagat 25740
cctccttcac tcccaaccag gcctacctga ccttgcagag cagctcttcg gagcctcgct 25800
ccggaggcat cggaaccctc cagtttgtgg aggagtttgt gccctcggtc tacttcaacc 25860
ccttctcggg atcgccaggc ctctacccgg acgagttcat accgaacttc gacgcagtga 25920
gagaagcggt ggacggctac gactgaatgt cccatggtga ctcggctgag ctcgctcggt 25980
tgaggcatct ggaccactgc cgccgcctgc gctgcttcgc ccgggagagc tgcggactca 26040
tctactttga gtttcccgag gagcacccca acggccctgc acacggagtg cggatcaccg 26100
tagagggcac caccgagtct cacctggtca ggttcttcac ccagcaaccc ttcctggtcg 26160
agcgggaccg gggcgccacc acctacaccg tctactgcat ctgtccaacc ccgaagttgc 26220
atgagaattt ttgttgtact ctttgtggtg agtttaataa aagctaaact cttgcaatac 26280
tctggacctt gtcgtcgtca actcaacgag accgtctacc tcaccaacca gactgaggta 26340
aaactcacct gcagaccaca caagacctat atcatctggt tcttcgagaa cacctcattt 26400
gcagtctcca acactcactg cactagtcca tgaactgatg ttgattaaaa gcccaaaaac 26460
caatcagccc cttcccccat ttccccatcc cccaattact cataaaaaat aaatcattgg 26520
aattaatcat tcaataaaga tcacttactt gaaatctgaa agtatgtctc tggtgtagtt 26580
gttcagcagc acctcggtac cctcctccca gctctggtac tccagtcccc ggcgggcggc 26640
gaacttcctc cacaccttga aagggatgtc aaattcctgg tccacaattt tcattgtctt 26700
ccctctcaga tggcaaagag gctccgggtg gaagatgact tcaaccccgt ctacccctat 26760
ggctacgcgc ggaatcagaa tatccccttc ctcactcccc cctttgtctc ctccgatgga 26820
ttcaaaaact tcccccctgg ggtcctgtca cttaaactgg ctgatccaat caccatcaac 26880
aatggggatg tctcacttaa ggtgggaggg ggacttgctg tagagcaaca gactggtaac 26940
ctaagcgtaa accctgatgc acccttgcaa gttgcaagtg ataagctaca gcttgctctg 27000
gctcctccat tcgaggtcag agatggaaag cttgctttaa aggcaggtaa tggattaaaa 27060
gtactagata attccattac tggattgact ggattattga atacacttgt ggtattaact 27120
ggaaggggaa taggaacgga ggaattaaaa aatgacgatg gtgtaacaaa caaaggagtc 27180
ggcttgcgtg taagacttgg agatgacggc gggctgacat ttgataaaaa gggtgattta 27240
gtagcctgga ataaaaaaga tgacaggcgc accctgtgga caacccctga cacatctcca 27300
aattgcaaaa tgagtacaga aaaggattct aaacttacgt tgacacttac aaagtgtgga 27360
agtcaggttc tgggaaatgt atctttactt gcagttacag gtgaatatca tcaaatgact 27420
gctactacaa agaaggatgt aaaaatatct ttactatttg atgagaatgg aattctatta 27480
ccatcttcgt cccttagcaa agattattgg aattacagaa gtgatgattc tattgtatct 27540
caaaaatata ataatgcagt tccattcatg ccaaacctga cagcttatcc aaaaccaagc 27600
gctcaaaatg caaaaaacta ttcaagaact aaaatcataa gtaatgtcta cttaggtgct 27660
cttacctacc aacctgtaat tatcactatt gcatttaatc aggaaactga aaatggatgt 27720
gcttattcta taacatttac cttcacttgg caaaaagact attctgccca acagtttgat 27780
gttacatctt ttaccttctc atatcttacc caagagaaca aagacaaaga ctaataaaat 27840
gttttgaact gaatttatga atctttattt atttttacac cagcacgggt agtcagtttc 27900
ccaccaccag cccatttcac agtgtaaaca gtcctttctc cccggctggc cttaaaaagc 27960
atcatatcat gggtaacaga catattctta ggtgttatat tccacacggt ttcctgtcga 28020
gccaaacgct catcagtgat attaataaac tccccgggca gctcacttaa gttcatgtcg 28080
ctgtccagct gctgagccac aggctgctgt ccaacttgcg gttgcttaac gggcggcgaa 28140
ggagaagtcc acgcctacat gggggtagag tcataatcgt gcatcaggat agggcggtgg 28200
tgctgcagca gcgcgcgaat aaactgctgc cgccgccgct ccgtcctgca ggaatacaac 28260
atggcagtgg tctcctcagc gatgattcgc accgcccgca gcataaggcg ccttgtcctc 28320
cgggcacagc agcgcaccct gatctcactt aaatcagcac agtaactgca gcacagcacc 28380
acaatattgt tcaaaatccc acagtgcaag gcgctgtatc caaagctcat ggcggggacc 28440
acagaaccca cgtggccatc ataccacaag cgcaggtaga ttaagtggcg acccctcata 28500
aacacgctgg acataaacat tacctctttt ggcatgttgt aattcaccac ctcccggtac 28560
catataaacc tctgattaaa catggcgcca tccaccacca tcctaaacca gctggccaaa 28620
acctgcccgc cggctataca ctgcagggaa ccgggactgg aacaatgaca gtggagagcc 28680
caggactcgt aaccatggat catcatgctc gtcatgatat caatgttggc acaacacagg 28740
cacacgtgca tacacttcct caggattaca agctcctccc gcgttagaac catatcccag 28800
ggaacaaccc attcctgaat cagcgtaaat cccacactgc agggaagacc tcgcacgtaa 28860
ctcacgttgt gcattgtcaa agtgttacat tcgggcagca gcggatgatc ctccagtatg 28920
gtagcgcggg tttctgtctc aaaaggaggt agacgatccc tactgtacgg agtgcgccga 28980
gacaaccgag atcgtgttgg tcgtagtgtc atgccaaatg gaacgccgga cgtagtcatt 29040
gaaatggatt ctcttgcgta ccttgtcgta cttctgccag cagaaagtgg ctcgggaaca 29100
gcagatacct ttcctcctgc tgtccttccg ctgctgacgc tcagtcatcc aactgaagta 29160
cagccattcc cgcaggttct ccagcagctc ctgtgcatct gatgaaacaa aagtcccgtc 29220
gatgcggatt ccccttaaaa catcagccag gacattgtag gccatcccaa tccagttaat 29280
gcatcctgat ctatcatgaa gaggaggtgg gggaagaact ggaagaacca tttttattcc 29340
aagcggtctc gaaggacgat aaagtgcaag tcacgcaggt gacagcgttc cccgccgctg 29400
tgctggtgga aacagacagc caggtcaaaa cccactctat tttcaaggtg ctcgactgtg 29460
gcttcgagca gtggctctac gcgtacatcc agcataagaa tcacattaaa ggctggacct 29520
ccatcgattt catcaatcat caggttacac tcattcacca tccccaggta attctcattt 29580
ttccagcctt ggattatttc tacaaattgt tggtgtaagt ccactccgca catgtggaaa 29640
agttcccaca gcgccccctc cactttcata atcaggcaga ccttcatatt agaaacagat 29700
cctgctgctc caccacctgc agcgtgttca aaacaacaag attcaatgag gttctgccct 29760
ctgccctcag ctcacgtctc agcgtcagct gcaaaaagtc actcaagtcc tcagccacta 29820
cagctgacaa ttcagagcca gggctaagcg tgggactggc aagcgtgagt gagtacttta 29880
atgctccaaa gctagcaccc aaaaactgca tgctggaata agctctcttt gtgtcaccgg 29940
tgatgccttc caataggtga gtgataaagc gaggtagttt ttctttaatc atttgagtaa 30000
tagaaaagtc ctctaaataa gtcactagga ccccaggaac cacaatgtgg tagctgacag 30060
cgtgtcgctc aagcatggtt agtagagatg agagtctgaa aaacagaaag catgcactaa 30120
accagagttg ccagtctcac tgaaggaaaa atcactctct ccagcagcaa agtgcccact 30180
gggtggccct ctcggacata caaaaatcga tccgtgtggt taaagagcag cacagttagc 30240
tcctgtcttc tcccagcaaa gatcacatcg gactgggtta gtatgcccct ggaatggtag 30300
tcattcaagg ccataaatct gccttggtag ccattaggaa tcagcacgct cactctcaag 30360
tgaaccaaaa ccaccccatg cggaggaatg tggaaagatt ctgggcaaaa aaaggtatat 30420
ctattgctag tcccttcctg gacgggagca atccctccag ggctatctat gaaagcatac 30480
agagattcag ccatagctca gcccgcttac cagtagacag agagcacagc agtacaagcg 30540
ccaacagcag cgactgacta cccactgacc cagctcccta tttaaaggca ccttacactg 30600
acgtaatgac caaaggtcta aaaaccccgc caaaaaaaca cacacgccct gggtgttttt 30660
cgcgaaaaca cttccgcgtt ctcacttcct cgtatcgatt tcgtgactca acttccgggt 30720
tcccacgtta cgtcacttct gcccttacat gtaactcagc cgtagggcgc catcttgccc 30780
acgtccaaaa tggcttccat gtccggccac gcctccgcgg cgaccgttag ccgtgcgtcg 30840
tgacgtcatt tgcatcaccg tttctcgtcc aatcagcgtt ggctccgccc caaaaccgtt 30900
aaaattcaaa agctcatttg catattaact tttgtttact ttgtggggta tattattgat 30960
gatgttaatt aagcaggcca tgctgtccag gcaggtagat gacgaccatc agggacagct 31020
tcaaggccag caaaaggcca ggaaccgtaa aaaggccgcg ttgctggcgt ttttccatag 31080
gctccgcccc cctgacgagc atcacaaaaa tcgacgctca agtcagaggt ggcgaaaccc 31140
gacaggacta taaagatacc aggcgtttcc ccctggaagc tccctcgtgc gctctcctgt 31200
tccgaccctg ccgcttaccg gatacctgtc cgcctttctc ccttcgggaa gcgtggcgct 31260
ttctcatagc tcacgctgta ggtatctcag ttcggtgtag gtcgttcgct ccaagctggg 31320
ctgtgtgcac gaaccccccg ttcagcccga ccgctgcgcc ttatccggta actatcgtct 31380
tgagtccaac ccggtaagac acgacttatc gccactggca gcagccactg gtaacaggat 31440
tagcagagcg aggtatgtag gcggtgctac agagttcttg aagtggtggc ctaactacgg 31500
ctacactaga aggacagtat ttggtatctg cgctctgctg aagccagtta ccttcggaaa 31560
aagagttggt agctcttgat ccggcaaaca aaccaccgct ggtagcggtg gtttttttgt 31620
ttgcaagcag cagattacgc gcagaaaaaa aggatctcaa gaagatcctt tgatcttttc 31680
tacggggtct gacgctcagt ggaacgaaaa ctcacgttaa gggattttgg tcatgagatt 31740
atcaaaaagg atcttcacct agatcctttt aaattaaaaa tgaagtttta aatcaatcta 31800
aagtatatat gagtaaactt ggtctgacag ttaccaatgc ttaatcagtg aggcacctat 31860
ctcagcgatc tgtctatttc gttcatccat agttgcctga ctccccgtcg tgtagataac 31920
tacgatacgg gagggcttac catctggccc cagtgctgca atgataccgc gagacccacg 31980
ctcaccggct ccagatttat cagcaataaa ccagccagcc ggaagggccg agcgcagaag 32040
tggtcctgca actttatccg cctccatcca gtctattaat tgttgccggg aagctagagt 32100
aagtagttcg ccagttaata gtttgcgcaa cgttgttgcc attgctgcag gcatcgtggt 32160
gtcacgctcg tcgtttggta tggcttcatt cagctccggt tcccaacgat caaggcgagt 32220
tacatgatcc cccatgttgt gcaaaaaagc ggttagctcc ttcggtcctc cgatcgttgt 32280
cagaagtaag ttggccgcag tgttatcact catggttatg gcagcactgc ataattctct 32340
tactgtcatg ccatccgtaa gatgcttttc tgtgactggt gagtactcaa ccaagtcatt 32400
ctgagaatag tgtatgcggc gaccgagttg ctcttgcccg gcgtcaacac gggataatac 32460
cgcgccacat agcagaactt taaaagtgct catcattgga aaacgttctt cggggcgaaa 32520
actctcaagg atcttaccgc tgttgagatc cagttcgatg taacccactc gtgcacccaa 32580
ctgatcttca gcatctttta ctttcaccag cgtttctggg tgagcaaaaa caggaaggca 32640
aaatgccgca aaaaagggaa taagggcgac acggaaatgt tgaatactca tactcttcct 32700
ttttcaatat tattgaagca tttatcaggg ttattgtctc atgagcggat acatatttga 32760
atgtatttag aaaaataaac aaataggggt tccgcgcaca tttccccgaa aagtgccacc 32820
tgacgtctaa gaaaccatta ttatcatgac attaacctat aaaaataggc gtatcacgag 32880
gccctttcgt cttcaagaat tggtcgatgg caaacagcta ttatgggtat tatgggttcg 32940
aattaattaa tcga 32954
<210> 21
<211> 32930
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVRPtr12.luc
<400> 21
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat cccagccagt gggagcaaaa tgaaaccaat gttaataaaa 18000
cacacacctt tgggatggca gccatgaaag gagaagctat tgacaaaaat ggtctgcaaa 18060
ttggaactga cgcggcggat caggataaac caatttatgc agataaaact ttccagccag 18120
aacctcaagt aggagaggaa gactggattg ataaagcaga tttctatggc ggaagagctc 18180
ttaaaaaaga cactaaaatg aaaccatgct atggatcttt tgctagacct actaatgaga 18240
aaggaggtca ggcaaagttc aaaccagtta atgaaggaga acaacctaaa gatctggata 18300
tagatatgaa cttctttgac ccaaccacta ttaacacacc agatgtagtg ctgtacactg 18360
aaaatgttaa tcttgaaaca ccagacactc atgtggttta caaggcagga acttcagatg 18420
acagttctga ggtcaatttg gctcagcagt ccatgccaaa cagacccaac tacattggct 18480
ttagggacaa ctttgtaggt ctcatgtatt acaacagcac cggaaatatg ggtgtgctgg 18540
ctggtcaggc ttctcagttg aacgctgtgg tcgacttgca agacagaaac accgagttat 18600
cttaccagct attgctagat tctctgggtg acagaaccag atactttagc atgtggaact 18660
ctgcggtgga cagttacgat ccagatgtca ggatcattga aaatcacggt gtggaagatg 18720
aacttccaaa ctattgcttc ccattggatg gtgtgggcac taatactgca taccaaggcg 18780
ttaaagttaa gacaactaat ggaaacgaca cgtgggaaaa agatgaaact gtttatgagt 18840
ttaatcaaat tggcaagggg gatatctatg ccatggagat caacctgcag gccaacctgt 18900
ggaagagttt tctgtactcg aacgtggccc tgtacctgcc cgactcctac aagtacacgc 18960
cggccaacgt caagctgccc gccaacacca acacctacga gtacatgaac ggccgcgtgg 19020
tagccccctc gctggtggac gcctacatca acatcggcgc ccgctggtcg ttggatccca 19080
tggacaacgt caaccccttc aaccaccacc gcaatgcggg cctgcgctac cgctccatgc 19140
tgctgggcaa cggccgctac gtgcccttcc acatccaagt gccccaaaag ttctttgcca 19200
tcaagaacct gctcctgctc ccgggctcct acacctacga gtggaacttc cgcaaggacg 19260
tcaacatgat cctgcagagt tccctcggca acgacctgcg cgtcgacggc gcctccgtcc 19320
gcttcgacag cgtcaaccta tacgccactt tcttccccat ggcgcacaac accgcttcaa 19380
ccttggaagc catgctgcgc aacgacacca acgaccagtc cttcaacgac tacctctcgg 19440
ccgccaacat gctctacccc atcccggcca aggccaccaa cgtgcccatc tccatcccat 19500
cgcgcaactg ggccgccttc cgcggctgga gtttcacccg gctcaagacc aaggaaactc 19560
cttccctcgg ctcgggtttc gacccctact ttgtctactc gggctccatc ccctacctcg 19620
acgggacctt ctacctcaac cacaccttca agaaggtctc catcatgttc gactcctcgg 19680
tcagctggcc cggcaacgac cggctgctca cgccgaacga gttcgagatc aagcgcagcg 19740
tcgacgggga gggctacaac gtggcccaat gcaacatgac caaggactgg ttcctcgtcc 19800
agatgctctc ccactacaac atcggctacc agggcttcca cgtgcccgag ggctacaagg 19860
accgcatgta ctccttcttc cgcaacttcc agcccatgag caggcaggtg gtcgatgaga 19920
tcaactacaa ggactacaag gccgtcaccc tgcccttcca gcacaataac tcgggcttca 19980
ccggctacct cgcacccacc atgcgccagg ggcagcccta ccccgccaac ttcccctacc 20040
cgctcatcgg tcagacagcc gtgccctccg tcacccagaa aaagttcctc tgcgacaggg 20100
tcatgtggcg catccccttc tccagcaact tcatgtccat gggcgccctc accgacctgg 20160
gtcagaacat gctctacgcc aactcggccc acgcgctcga catgaccttc gaggtggacc 20220
ccatggatga gcccaccctc ctctatcttc tcttcgaagt tttcgacgtg gtcagagtac 20280
accagccgca ccgcggcgtc atcgaggccg tctacctgcg cacgcccttc tccgccggca 20340
acgccaccac ctaagcatga gcggctccag cgaacgagag ctcgcggcca tcgtgcgcga 20400
cctgggctgc gggccctact ttttgggcac ccacgacaag cgcttcccgg gctttctcgc 20460
cggcgacaag ctggcctgcg ccatcgtcaa cacggccggc cgcgagaccg gaggcgtgca 20520
ctggctcgcc ttcggctgga acccgcgctc gcgcacctgc tacatgttcg acccctttgg 20580
gttctcggac cgccggctca agcagattta cagcttcgag tacgaggcca tgctgcgccg 20640
cagcgccctg gcctcctcgc ccgaccgctg tctcagcctc gagcagtcca ctcagaccgt 20700
gcaggggccc gactccgccg cctgcggact cttctgttgc atgttcttgc atgccttcgt 20760
gcactggccc gaccgaccca tggacggaaa ccccaccatg aacttgctga cgggggtgcc 20820
caacggcatg ctacaatcgc cacaggtgct gcccaccctc aggcgcaacc aggaggaact 20880
ctaccgcttc ctcgcgcgcc actcccctta ctttcgctcc caccgcgccg ccatcgaaca 20940
cgccaccgct tttgacaaaa tgaaacaact gcgtgtatct caataaacag cacttttatt 21000
ttacatgcac tggagtatat gcaagttatt taaaagtcga aggggttctc gcgctcgtcg 21060
ttgtgcgccg cgctggggag ggccacgttg cggtactggt acttgggctg ccacttgaac 21120
tcggggatca ccagtttggg cactggggtc tcggggaagg tctcgctcca catgcgccgg 21180
ctcatctgca gggcgcccag catgtccggg gcggagatct tgaaatcgca gttggggccg 21240
gtgctctgcg cgcgcgagtt gcggtacacg gggttgcagc actggaacac catcagactg 21300
gggtacttca cactagccag cacgctcttg tcgctgatct gatccttgtc cagatcctcg 21360
gcgttgctca ggccgaacgg ggtcatcttg cacagctggc gtcccaggaa gggcacgctc 21420
tgaggcttgt ggttacactc gcagtgcacg ggcatcagca tcatccccgc gccgcgctgc 21480
atattcgggt agagggcctt gacaaaggcc gcgatctgct tgaaagcttg ctgggccttg 21540
gccccctcgc tgaaaaacag gccgcagctc ttcccgctga actggttatt cccacacccg 21600
gcatcctgca cgcagcagcg cgcgtcatgg ctggtcagtt gcaccacgct ccgtccccag 21660
cggttctggg tcaccttagc cttgctgggc tgctccttca acgcgcgctg cccgttctcg 21720
ctggtcacat ccatctccac cacgtggtcc ttgtggatca tcatcgtccc gtgcagacac 21780
ttgagctggc cttccacctc ggtgcagccg tgatcccaca gggcgcaacc ggtgcactcc 21840
cagttcttgt gcgcaatccc gctgtggctg aagatgtaac cttgcaacat gcggcccatg 21900
atggtgctaa atgctttctg ggtggtgaag gtcagttgca tcccgcgggc ctcctcgttc 21960
atccaggtct ggcacatctt ctggaagatc tcggtctgct cgggcatgag cttgtaagca 22020
tcgcgcaggc cgctgtcgac gcggtagcgt tccatcagca cgttcatggt atccatgccc 22080
ttctcccagg acgagaccag aggcagactc agagggttgc gtacgttcag gacaccgggg 22140
gtcgcgggct cgacgatgcg ttttccgtcc ttgccttcct tcaatagaac cggcggctgg 22200
ctgaatccca ctcccacgat cacggcatct tcctggggca tctcttcgtc ggggtctacc 22260
ttggtcacat gcttggtctt tctggcttgc ttcttttttg gagggctgtc cacggggagc 22320
acgtcctcct cggaagaccc ggagcccacc cgctgatact ttcggcgctt ggtgggcaga 22380
ggaggtggcg gcgaggggct cctctcctgc tccggcggat agcgcgccga cccgtggccc 22440
cggggcggag tggcctctcg gcccatgaac cggcgcacgt cctgactgcc gccggccatt 22500
gtttcctagg ggaagatgga ggagcagccg cgtaagcagg agcaggagga ggacttaacc 22560
acccacgagc aacccaaaat cgagcaggac ctgggcttcg aagagccggc tcgtctagaa 22620
cccccacagg atgaacagga gcacgagcaa gacgcaggcc aggaggagac cgacgctggg 22680
ctcgagcatg gctacctggg aggagaggag gatgtgctgc tgaaacacct gcagcgccag 22740
tccctcatcc tccgggacgc cctggccgac cggagcgaaa cccccctcag cgtcgaggag 22800
ctgtgtcggg cctacgagct caacctcttc tcgccgcgcg taccccccaa acgccagccc 22860
aacggcacct gcgagcccaa cccgcgtctc aacttctatc ccgtctttgc ggtccccgaa 22920
gccctcgcca cctatcacat ctttttcaag aaccaaaaga tccccgtctc ctgccgcgcc 22980
aaccgcacca gcgccgacgc gctcctcgct ttggggcccg gcgcgcgcat acctgatatc 23040
gcttccctgg aagaggtgcc caagatcttc gaagggctcg gtcgggacga gacgcgcgcg 23100
gcgaacgctc tgaaagaaac agcagaggaa gagggtcaca ctagcgccct ggtagagttg 23160
gaaggcgaca acgccaggct ggccgtgctc aagcgcagcg tcgagcttac ccacttcgcc 23220
taccccgccg tcaacctccc gcccaaggtc atgcgtcgca tcatggatca gctcatcatg 23280
ccccacatcg aggccctcga tgaaagtcag gagcagcgcc ccgaggacgc ccggcccgtg 23340
gtcagcgacg agatgctcgc gcgctggctc gggacccgcg acccccaggc tttggaacag 23400
cggcgcaaac tcatgctggc cgtggtcctg gtcacccttg agctcgaatg catgcgccgc 23460
tttttcagcg accccgagac cctgcgcaag gtcgaggaga ccctgcacta cactttcagg 23520
cacggtttcg tcaggcaggc ctgcaagatc tccaacgtgg agctgaccaa cctggtctcc 23580
tgcctgggga tcctgcacga gaaccgcctg ggccagaccg tgctccactc taccctgaag 23640
ggcgaggcgc ggcgggacta tgtccgcgac tgcgtctttc tctttctctg ccacacatgg 23700
caagcggcca tgggcgtgtg gcagcagtgt ctcgaggacg agaacctaaa ggagctggac 23760
aagcttcttg ctagaaacct taaaaagctg tggacgggct tcgacgagcg caccgtcgcc 23820
tcggacctgg ccgagatcgt cttccccgag cgcctgagac agacgctgaa aggcgggctg 23880
cccgacttca tgagccagag catgttgcaa aactaccgca ctttcattct tgagcgatca 23940
ggcatcctgc ccgccacctg caacgccttc ccctccgact ttgtaccgct gagctaccgc 24000
gagtgtcccc cgccgctgtg gagccactgc tacctcttgc agctggccaa ctacatcgcc 24060
taccactcgg acgtgatcga ggacgtgagc ggcgaggggc tgctcgagtg ccactgtcgc 24120
tgcaacctgt gctccccgca tcgctccctg gtctgcaacc cccagctcct gagcgagacc 24180
caggtcatcg gtaccttcga gctgcaaggt ccgcaggagt ccaccgctcc gctgaaactc 24240
acgccggggt tgtggacttc cgcgtacctg cgcaaatttg tacccgaaga ctaccacgcc 24300
catgagataa agttctttga ggaccaatcg cgtccgcagc acgcggatct cacggcctgc 24360
gtcatcaccc agggcgcgat cctcgcccaa ttgcacgcca tccaaaaatc ccgccaagag 24420
tttcttctga aaaagggtag aggggtctac ctggaccccc agacgggcga ggtgctcaac 24480
ccgggtctcc cccagcatgc cgaggaagaa gcaggagccg ctagtggagg agatggaaga 24540
agaatgggac agccaggcag aggaggacga atgggaggag gagacagagg aggaagaatt 24600
ggaagaggtg gaagaggagc aggcaacaga gcagcccgtc gccgcaccat ccgcgccggc 24660
agccccgccg gtcacggata caacctccgc tccggtcaag cctcctcgta gatgggatca 24720
agtgaagggt gacggtaagc acgagcggca gggctaccga tcatggaggg cccacaaagc 24780
cgcgatcatc gcctgcttgc aagactgcgg ggggaacatc gctttcgccc gccgctacct 24840
gctcttccac cgcggggtga acatcccccg caacgtgttg cattactacc gtcaccttca 24900
cagctaagaa aaagcaagtc aaaggagtcg ccggaggagg aggaggaggc ctgaggatcg 24960
cggcgaacga gcccttgacc accagggagc tgaggaaccg gatcttcccc actctttatg 25020
ccatttttca gcagagtcga ggtcagcagc aagagctcaa agtaaaaaac cggtctctgc 25080
gctcgctcac ccgcagttgc ttgtaccaca aaaacgaaga tcagctgcag cgcactctcg 25140
aagacgccga ggctctgttc cacaagtact gcgcgctcac tcttaaagac taaggcgcgc 25200
ccacccggaa aaaaggcggg aattacctca tcgccaccat gagcaaggag attcccaccc 25260
cttacatgtg gagctatcag ccccaaatgg gcctggccgc gggcgcctcc caggactact 25320
ccacccgcat gaactggctc agtgccggcc cctcgatgat ctcacgggtc aacggggtcc 25380
gcagtcatcg aaaccagata ttgttggagc aggcggcggt cacctccacg cccagggcaa 25440
agctcaaccc gcgtaattgg ccctccaccc tggtgtatca ggaaatcccc gggccgacta 25500
ccgtactact tccgcgtgac gcactggccg aagtccgcat gactaactca ggtgtccagc 25560
tggccggcgg cgcttcccgg tgcccgctcc gcccacaatc gggtataaaa accctggtga 25620
tccgaggcag aggcacacag ctcaacgacg agttggtgag ctcttcgatc ggtctgcgac 25680
cggacggagt gttccaacta gccggagccg ggagatcctc cttcactccc aaccaggcct 25740
acctgacctt gcagagcagc tcttcggagc ctcgctccgg aggcatcgga accctccagt 25800
ttgtggagga gtttgtgccc tcggtctact tcaacccctt ctcgggatcg ccaggcctct 25860
acccggacga gttcataccg aacttcgacg cagtgagaga agcggtggac ggctacgact 25920
gaatgtccca tggtgactcg gctgagctcg ctcggttgag gcatctggac cactgccgcc 25980
gcctgcgctg cttcgcccgg gagagctgcg gactcatcta ctttgagttt cccgaggagc 26040
accccaacgg ccctgcacac ggagtgcgga tcaccgtaga gggcaccacc gagtctcacc 26100
tggtcaggtt cttcacccag caacccttcc tggtcgagcg ggaccggggc gccaccacct 26160
acaccgtcta ctgcatctgt ccaaccccga agttgcatga gaatttttgt tgtactcttt 26220
gtggtgagtt taataaaagc taaactcttg caatactctg gaccttgtcg tcgtcaactc 26280
aacgagaccg tctacctcac caaccagact gaggtaaaac tcacctgcag accacacaag 26340
acctatatca tctggttctt cgagaacacc tcatttgcag tctccaacac tcactgcact 26400
agtccatgaa ctgatgttga ttaaaagccc aaaaaccaat cagccccttc ccccatttcc 26460
ccatccccca attactcata aaaaataaat cattggaatt aatcattcaa taaagatcac 26520
ttacttgaaa tctgaaagta tgtctctggt gtagttgttc agcagcacct cggtaccctc 26580
ctcccagctc tggtactcca gtccccggcg ggcggcgaac ttcctccaca ccttgaaagg 26640
gatgtcaaat tcctggtcca caattttcat tgtcttccct ctcagatggc aaagaggctc 26700
cgggtggaag atgacttcaa ccccgtctac ccctatggct acgcgcggaa tcagaatatc 26760
cccttcctca ctcccccctt tgtctcctcc gatggattca aaaacttccc ccctggggtc 26820
ctgtcactta aactggctga tccaatcacc atcaacaatg gggatgtctc acttaaggtg 26880
ggagggggac ttgctgtaga gcaacagact ggtaacctaa gcgtaaaccc tgatgcaccc 26940
ttgcaagttg caagtgataa gctacagctt gctctggctc ctccattcga ggtcagagat 27000
ggaaagcttg ctttaaaggc aggtaatgga ttaaaagtac tagataattc cattactgga 27060
ttgactggat tattgaatac acttgtggta ttaactggaa ggggaatagg aacggaggaa 27120
ttaaaaaatg acgatggtgt aacaaacaaa ggagtcggct tgcgtgtaag acttggagat 27180
gacggcgggc tgacatttga taaaaagggt gatttagtag cctggaataa aaaagatgac 27240
aggcgcaccc tgtggacaac ccctgacaca tctccaaatt gcaaaatgag tacagaaaag 27300
gattctaaac ttacgttgac acttacaaag tgtggaagtc aggttctggg aaatgtatct 27360
ttacttgcag ttacaggtga atatcatcaa atgactgcta ctacaaagaa ggatgtaaaa 27420
atatctttac tatttgatga gaatggaatt ctattaccat cttcgtccct tagcaaagat 27480
tattggaatt acagaagtga tgattctatt gtatctcaaa aatataataa tgcagttcca 27540
ttcatgccaa acctgacagc ttatccaaaa ccaagcgctc aaaatgcaaa aaactattca 27600
agaactaaaa tcataagtaa tgtctactta ggtgctctta cctaccaacc tgtaattatc 27660
actattgcat ttaatcagga aactgaaaat ggatgtgctt attctataac atttaccttc 27720
acttggcaaa aagactattc tgcccaacag tttgatgtta catcttttac cttctcatat 27780
cttacccaag agaacaaaga caaagactaa taaaatgttt tgaactgaat ttatgaatct 27840
ttatttattt ttacaccagc acgggtagtc agtttcccac caccagccca tttcacagtg 27900
taaacagtcc tttctccccg gctggcctta aaaagcatca tatcatgggt aacagacata 27960
ttcttaggtg ttatattcca cacggtttcc tgtcgagcca aacgctcatc agtgatatta 28020
ataaactccc cgggcagctc acttaagttc atgtcgctgt ccagctgctg agccacaggc 28080
tgctgtccaa cttgcggttg cttaacgggc ggcgaaggag aagtccacgc ctacatgggg 28140
gtagagtcat aatcgtgcat caggataggg cggtggtgct gcagcagcgc gcgaataaac 28200
tgctgccgcc gccgctccgt cctgcaggaa tacaacatgg cagtggtctc ctcagcgatg 28260
attcgcaccg cccgcagcat aaggcgcctt gtcctccggg cacagcagcg caccctgatc 28320
tcacttaaat cagcacagta actgcagcac agcaccacaa tattgttcaa aatcccacag 28380
tgcaaggcgc tgtatccaaa gctcatggcg gggaccacag aacccacgtg gccatcatac 28440
cacaagcgca ggtagattaa gtggcgaccc ctcataaaca cgctggacat aaacattacc 28500
tcttttggca tgttgtaatt caccacctcc cggtaccata taaacctctg attaaacatg 28560
gcgccatcca ccaccatcct aaaccagctg gccaaaacct gcccgccggc tatacactgc 28620
agggaaccgg gactggaaca atgacagtgg agagcccagg actcgtaacc atggatcatc 28680
atgctcgtca tgatatcaat gttggcacaa cacaggcaca cgtgcataca cttcctcagg 28740
attacaagct cctcccgcgt tagaaccata tcccagggaa caacccattc ctgaatcagc 28800
gtaaatccca cactgcaggg aagacctcgc acgtaactca cgttgtgcat tgtcaaagtg 28860
ttacattcgg gcagcagcgg atgatcctcc agtatggtag cgcgggtttc tgtctcaaaa 28920
ggaggtagac gatccctact gtacggagtg cgccgagaca accgagatcg tgttggtcgt 28980
agtgtcatgc caaatggaac gccggacgta gtcattgaaa tggattctct tgcgtacctt 29040
gtcgtacttc tgccagcaga aagtggctcg ggaacagcag atacctttcc tcctgctgtc 29100
cttccgctgc tgacgctcag tcatccaact gaagtacagc cattcccgca ggttctccag 29160
cagctcctgt gcatctgatg aaacaaaagt cccgtcgatg cggattcccc ttaaaacatc 29220
agccaggaca ttgtaggcca tcccaatcca gttaatgcat cctgatctat catgaagagg 29280
aggtggggga agaactggaa gaaccatttt tattccaagc ggtctcgaag gacgataaag 29340
tgcaagtcac gcaggtgaca gcgttccccg ccgctgtgct ggtggaaaca gacagccagg 29400
tcaaaaccca ctctattttc aaggtgctcg actgtggctt cgagcagtgg ctctacgcgt 29460
acatccagca taagaatcac attaaaggct ggacctccat cgatttcatc aatcatcagg 29520
ttacactcat tcaccatccc caggtaattc tcatttttcc agccttggat tatttctaca 29580
aattgttggt gtaagtccac tccgcacatg tggaaaagtt cccacagcgc cccctccact 29640
ttcataatca ggcagacctt catattagaa acagatcctg ctgctccacc acctgcagcg 29700
tgttcaaaac aacaagattc aatgaggttc tgccctctgc cctcagctca cgtctcagcg 29760
tcagctgcaa aaagtcactc aagtcctcag ccactacagc tgacaattca gagccagggc 29820
taagcgtggg actggcaagc gtgagtgagt actttaatgc tccaaagcta gcacccaaaa 29880
actgcatgct ggaataagct ctctttgtgt caccggtgat gccttccaat aggtgagtga 29940
taaagcgagg tagtttttct ttaatcattt gagtaataga aaagtcctct aaataagtca 30000
ctaggacccc aggaaccaca atgtggtagc tgacagcgtg tcgctcaagc atggttagta 30060
gagatgagag tctgaaaaac agaaagcatg cactaaacca gagttgccag tctcactgaa 30120
ggaaaaatca ctctctccag cagcaaagtg cccactgggt ggccctctcg gacatacaaa 30180
aatcgatccg tgtggttaaa gagcagcaca gttagctcct gtcttctccc agcaaagatc 30240
acatcggact gggttagtat gcccctggaa tggtagtcat tcaaggccat aaatctgcct 30300
tggtagccat taggaatcag cacgctcact ctcaagtgaa ccaaaaccac cccatgcgga 30360
ggaatgtgga aagattctgg gcaaaaaaag gtatatctat tgctagtccc ttcctggacg 30420
ggagcaatcc ctccagggct atctatgaaa gcatacagag attcagccat agctcagccc 30480
gcttaccagt agacagagag cacagcagta caagcgccaa cagcagcgac tgactaccca 30540
ctgacccagc tccctattta aaggcacctt acactgacgt aatgaccaaa ggtctaaaaa 30600
ccccgccaaa aaaacacaca cgccctgggt gtttttcgcg aaaacacttc cgcgttctca 30660
cttcctcgta tcgatttcgt gactcaactt ccgggttccc acgttacgtc acttctgccc 30720
ttacatgtaa ctcagccgta gggcgccatc ttgcccacgt ccaaaatggc ttccatgtcc 30780
ggccacgcct ccgcggcgac cgttagccgt gcgtcgtgac gtcatttgca tcaccgtttc 30840
tcgtccaatc agcgttggct ccgccccaaa accgttaaaa ttcaaaagct catttgcata 30900
ttaacttttg tttactttgt ggggtatatt attgatgatg ttaattaagc aggccatgct 30960
gtccaggcag gtagatgacg accatcaggg acagcttcaa ggccagcaaa aggccaggaa 31020
ccgtaaaaag gccgcgttgc tggcgttttt ccataggctc cgcccccctg acgagcatca 31080
caaaaatcga cgctcaagtc agaggtggcg aaacccgaca ggactataaa gataccaggc 31140
gtttccccct ggaagctccc tcgtgcgctc tcctgttccg accctgccgc ttaccggata 31200
cctgtccgcc tttctccctt cgggaagcgt ggcgctttct catagctcac gctgtaggta 31260
tctcagttcg gtgtaggtcg ttcgctccaa gctgggctgt gtgcacgaac cccccgttca 31320
gcccgaccgc tgcgccttat ccggtaacta tcgtcttgag tccaacccgg taagacacga 31380
cttatcgcca ctggcagcag ccactggtaa caggattagc agagcgaggt atgtaggcgg 31440
tgctacagag ttcttgaagt ggtggcctaa ctacggctac actagaagga cagtatttgg 31500
tatctgcgct ctgctgaagc cagttacctt cggaaaaaga gttggtagct cttgatccgg 31560
caaacaaacc accgctggta gcggtggttt ttttgtttgc aagcagcaga ttacgcgcag 31620
aaaaaaagga tctcaagaag atcctttgat cttttctacg gggtctgacg ctcagtggaa 31680
cgaaaactca cgttaaggga ttttggtcat gagattatca aaaaggatct tcacctagat 31740
ccttttaaat taaaaatgaa gttttaaatc aatctaaagt atatatgagt aaacttggtc 31800
tgacagttac caatgcttaa tcagtgaggc acctatctca gcgatctgtc tatttcgttc 31860
atccatagtt gcctgactcc ccgtcgtgta gataactacg atacgggagg gcttaccatc 31920
tggccccagt gctgcaatga taccgcgaga cccacgctca ccggctccag atttatcagc 31980
aataaaccag ccagccggaa gggccgagcg cagaagtggt cctgcaactt tatccgcctc 32040
catccagtct attaattgtt gccgggaagc tagagtaagt agttcgccag ttaatagttt 32100
gcgcaacgtt gttgccattg ctgcaggcat cgtggtgtca cgctcgtcgt ttggtatggc 32160
ttcattcagc tccggttccc aacgatcaag gcgagttaca tgatccccca tgttgtgcaa 32220
aaaagcggtt agctccttcg gtcctccgat cgttgtcaga agtaagttgg ccgcagtgtt 32280
atcactcatg gttatggcag cactgcataa ttctcttact gtcatgccat ccgtaagatg 32340
cttttctgtg actggtgagt actcaaccaa gtcattctga gaatagtgta tgcggcgacc 32400
gagttgctct tgcccggcgt caacacggga taataccgcg ccacatagca gaactttaaa 32460
agtgctcatc attggaaaac gttcttcggg gcgaaaactc tcaaggatct taccgctgtt 32520
gagatccagt tcgatgtaac ccactcgtgc acccaactga tcttcagcat cttttacttt 32580
caccagcgtt tctgggtgag caaaaacagg aaggcaaaat gccgcaaaaa agggaataag 32640
ggcgacacgg aaatgttgaa tactcatact cttccttttt caatattatt gaagcattta 32700
tcagggttat tgtctcatga gcggatacat atttgaatgt atttagaaaa ataaacaaat 32760
aggggttccg cgcacatttc cccgaaaagt gccacctgac gtctaagaaa ccattattat 32820
catgacatta acctataaaa ataggcgtat cacgaggccc tttcgtcttc aagaattggt 32880
cgatggcaaa cagctattat gggtattatg ggttcgaatt aattaatcga 32930
<210> 22
<211> 32972
<212> DNA
<213> 人工序列
<220>
<223> pAd26.HVRPtr13.luc
<400> 22
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gattagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ccgggaacgg tgcattggaa gcttggcatt 1320
ccggtactgt tggtaaagcc accatggaag acgccaaaaa cataaagaaa ggcccggcgc 1380
cattctatcc gctggaagat ggaaccgctg gagagcaact gcataaggct atgaagagat 1440
acgccctggt tcctggaaca attgctttta cagatgcaca tatcgaggtg gacatcactt 1500
acgctgagta cttcgaaatg tccgttcggt tggcagaagc tatgaaacga tatgggctga 1560
atacaaatca cagaatcgtc gtatgcagtg aaaactctct tcaattcttt atgccggtgt 1620
tgggcgcgtt atttatcgga gttgcagttg cgcccgcgaa cgacatttat aatgaacgtg 1680
aattgctcaa cagtatgggc atttcgcagc ctaccgtggt gttcgtttcc aaaaaggggt 1740
tgcaaaaaat tttgaacgtg caaaaaaagc tcccaatcat ccaaaaaatt attatcatgg 1800
attctaaaac ggattaccag ggatttcagt cgatgtacac gttcgtcaca tctcatctac 1860
ctcccggttt taatgaatac gattttgtgc cagagtcctt cgatagggac aagacaattg 1920
cactgatcat gaactcctct ggatctactg gtctgcctaa aggtgtcgct ctgcctcata 1980
gaactgcctg cgtgagattc tcgcatgcca gagatcctat ttttggcaat caaatcattc 2040
cggatactgc gattttaagt gttgttccat tccatcacgg ttttggaatg tttactacac 2100
tcggatattt gatatgtgga tttcgagtcg tcttaatgta tagatttgaa gaagagctgt 2160
ttctgaggag ccttcaggat tacaagattc aaagtgcgct gctggtgcca accctattct 2220
ccttcttcgc caaaagcact ctgattgaca aatacgattt atctaattta cacgaaattg 2280
cttctggtgg cgctcccctc tctaaggaag tcggggaagc ggttgccaag aggttccatc 2340
tgccaggtat caggcaagga tatgggctca ctgagactac atcagctatt ctgattacac 2400
ccgaggggga tgataaaccg ggcgcggtcg gtaaagttgt tccatttttt gaagcgaagg 2460
ttgtggatct ggataccggg aaaacgctgg gcgttaatca aagaggcgaa ctgtgtgtga 2520
gaggtcctat gattatgtcc ggttatgtaa acaatccgga agcgaccaac gccttgattg 2580
acaaggatgg atggctacat tctggagaca tagcttactg ggacgaagac gaacacttct 2640
tcatcgttga ccgcctgaag tctctgatta agtacaaagg ctatcaggtg gctcccgctg 2700
aattggaatc catcttgctc caacacccca acatcttcga cgcaggtgtc gcaggtcttc 2760
ccgacgatga cgccggtgaa cttcccgccg ccgttgttgt tttggagcac ggaaagacga 2820
tgacggaaaa agagatcgtg gattacgtcg ccagtcaagt aacaaccgcg aaaaagttgc 2880
gcggaggagt tgtgtttgtg gacgaagtac cgaaaggtct taccggaaaa ctcgacgcaa 2940
gaaaaatcag agagatcctc ataaaggcca agaagggcgg aaagatcgcc gtgtaattct 3000
agacgagatc cgaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc 3060
acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc 3120
atcaatgtat cttatcatgt ctagatccag gtaggtttga gtagtgggcg tggctaaggt 3180
gactataaag gcgggtgtct tacgagggtc tttttgcttt tctgcagaca tcatgaacgg 3240
gactggcggg gccttcgaag gggggctttt tagcccttat ttgacaaccc gcctgccggg 3300
atgggccgga gttcgtcaga atgtgatggg atcgacggtg gatgggcgcc cagtgcttcc 3360
agcaaattcc tcgaccatga cctacgcgac cgtggggaac tcgtcgctcg acagcaccgc 3420
cgcagccgcg gcagccgcag ccgccatgac agcgacgaga ctggcctcga gctacatgcc 3480
cagcagcggt agtagcccct ctgtgcccag ttccatcatc gccgaggaga aactgctggc 3540
cctgctggcc gagctggaag ccctgagccg ccagctggcc gccctgaccc agcaggtgtc 3600
cgagctccgc gaacagcagc agcagcaaaa taaatgattc aataaacaca gattctgatt 3660
caaacagcaa agcatcttta ttatttattt tttcgcgcgc ggtaggccct ggtccacctc 3720
tcccgatcat tgagagtgcg gtggattttt tccaggaccc ggtagaggtg ggattggatg 3780
ttgaggtaca tgggcatgag cccgtcccgt gggtggaggt agcaccactg catggcctcg 3840
tgctctgggg tcgtgttgta gatgatccag tcatagcagg ggcgctgggc gtggtgctgg 3900
atgatgtcct tgaggaggag actgatggcc acggggagcc ccttggtgta ggtgttggca 3960
aaacggttga gctgggaggg atgcatgcgg ggggagatga tgtgcagttt ggcctggatc 4020
ttgaggttgg cgatgttgcc acccagatcc cgccgggggt tcatgttgtg caggaccacc 4080
agaacggtgt agcccgtgca cttggggaac ttgtcatgca acttggaagg gaatgcgtgg 4140
aagaatttgg agacgccctt gtgcccgccc aggttttcca tgcactcatc catgatgatg 4200
gcaatgggcc cgtgggctgc ggctttggca aagacgtttc tggggtcaga gacatcgtaa 4260
ttatgctcct gggtgagatc atcataagac attttaatga atttggggcg gagggtgcca 4320
gattggggga cgatggttcc ctcgggcccc ggggcgaagt tcccctcgca gatctgcatc 4380
tcccaggctt tcatctcgga gggggggatc atgtccacct gcggggcgat gaaaaaaacg 4440
gtttccgggg cgggggtgat gagctgcgag gagagcaggt ttctcaacag ctgggacttg 4500
ccgcacccgg tcgggccgta gatgaccccg atgacgggtt gcaggtggta gttcaaggac 4560
atgcagctgc cgtcgtcccg gaggaggggg gccacctcgt tgagcttgtc tctgacttgg 4620
aggttttccc ggacgagctc gccgaggagg cggtccccgc ccagcgagag aagctcttgc 4680
agggaagcaa agtttttcag gggcttgagc ccgtcggcca tgggcatctt ggcgagggtc 4740
tgcgagagga gctccaggcg gtcccagagc tcggtgacgt gctctacggc atctcgatcc 4800
agcagacttc ctcgtttcgg gggttgggac gactgcgact gtagggcacg agacgatggg 4860
cgtccagcgc ggccagcgtc atgtccttcc agggtctcag ggtccgcgtg agggtggtct 4920
ccgtcacggt gaaggggtgg gccgcgggct gggcgcttgc aagggtgcgc ttgagactca 4980
tcctgctggt gctgaaacgg gcacggtctt cgccctgcgc gtcggcgaga tagcagttga 5040
ccatgagctc gtagttgagg gcctcggcgg cgtggccctt ggcgcggagc ttgcccttgg 5100
aagagcgccc gcaggcggga cagaggaggg attgcagggc gtagagcttg ggcgcgagaa 5160
agacggactc gggggcgaag gcgtccgctc cgcagtgggc gcagacggtc tcgcactcga 5220
ctagccaggt gagctcgggc tgctcggggt caaaaaccag ttttcccccg ttctttttga 5280
tgcgcttctt acctcgcgtc tccatgagtc tgtgtccgcg ctcggtgaca aacaggctgt 5340
ctgtgtcccc gtagacggac ttgatgggcc tgtcctgcag gggcgtcccg cggtcctcct 5400
cgtagagaaa ctcagaccac tctgagacga aggcgcgcgt ccacgccaag acaaaggagg 5460
ccacgtgcga ggggtagcgg tcgttgtcca ccagggggtc caccttttcc acggtatgca 5520
ggcacatgtc cccctcctcc gcatccaaga aggtgattgg cttgtaggtg taggccacgt 5580
gacctggggt tcccgacggg ggggtataaa agggggcggg tctgtgctcg tcctcactct 5640
cttccgcgtc gctgtccacg agcgccagct gttggggtag gtattccctc tcaagagcgg 5700
gcatgacctc ggcactcagg ttgtcagttt ctagaaacga ggaggatttg atgtgggcct 5760
gccctgccgc gatgcttttt aggagacttt catccatctg gtcagaaaag actatttttt 5820
tattgtcaag cttggtggcg aaggagccat agagggcgtt tgagagaagc ttggcgatgg 5880
atctcatggt ctgatttttg tcacggtcgg cgcgctcctt ggccgcgatg ttgagctgga 5940
catattcgcg cgcgacacac ttccattcgg ggaagacggt ggtgcgctcg tcgggcacga 6000
tcctgacgcg ccagccgcgg ttatgcaggg tgaccaggtc cacgctggtg gccacctcgc 6060
cgcgcagggg ctcgttggtc cagcagagtc tgccgccctt gcgcgagcag aacgggggca 6120
gcacatcaag cagatgctcg tcaggggggt ccgcatcgat ggtgaagatg cccggacaga 6180
gttccttgtc aaaataatcg atttttgagg atgcatcgtc caaggccatc tgccactcgc 6240
gggcggccag cgctcgctcg taggggttga ggggcggacc ccaaggcatg ggatgcgtga 6300
gggcggaggc gtacatgccg cagatgtcat agacatagat gggctccgag aggatgccga 6360
tgtaggtggg atagcagcgc cccccgcgga tgcttgcgcg cacgtagtca tacaactcgt 6420
gcgagggggc caagaaggcg gggccgagat tggtgcgctg gggctgctcg gcgcggaaga 6480
cgatctggcg aaagatggcg tgcgagttgg aggagatggt gggccgttgg aagatgttaa 6540
agtgggcgtg aggcaggcgg accgagtcgc ggatgaagtg cgcgtaggag tcttgcagct 6600
tggcgacgag ctcggcggtg acgaggacgt ccatggcgca gtagtccagc gtttcgcgga 6660
tgatgtcata actcgcctct cctttcttct cccacagctc gcggttgagg gcgtattcct 6720
cgtcatcctt ccagtactcc cggagcggga atcctcgatc gtccgcacgg taagagccca 6780
gcatgtagaa atggttcacg gccttgtagg gacagcagcc cttctccacg gggagggcgt 6840
aagcttgagc ggccttgcgg agcgaggtgt gcgtcagggc aaaggtgtcc ctgaccatga 6900
ctttcaagaa ctggtacttg aagtccgagt cgtcgcagcc gccgtgctcc cagagctcga 6960
aatcggtgcg cttcttcgag agggggttag gcagagcgaa agtgacgtca ttgaagagaa 7020
tcttgcctgc ccgcggcatg aaattgcggg tgatgcggaa agggcccggg acggaggctc 7080
ggttgttgat gacctgggcg gcgaggacga tctcgtcaaa gccgttgatg ttgtgcccga 7140
cgatgtagag ttccatgaat cgcgggcggc ctttgatgtg cggcagcttt ttgagctcct 7200
cgtaggtgag gtcctcgggg cattgcaggc cgtgctgctc gagcgcccac tcctggagat 7260
gtgggttggc ttgcatgaag gaagcccaga gctcgcgggc catgagggtc tggagctcgt 7320
cgcgaaagag gcggaactgc tggcccacgg ccatcttttc tggggtgacg cagtagaagg 7380
tgagggggtc ccgctcccag cgatcccagc gtaaacgcac ggcgagatcg cgagcgaggg 7440
cgaccagctc tgggtccccg gagaatttca tgaccagcat gaaggggacg agctgcttgc 7500
cgaaggaccc catccaggtg taggtttcta catcgtaggt gacaaagagc cgctccgtgc 7560
gaggatgaga gccgattggg aagaactgga tttcctgcca ccagttggac gagtggctgt 7620
tgatgtgatg aaagtagaaa tcccgccggc gaaccgagca ctcgtgctga tgcttgtaaa 7680
agcgtccgca gtactcgcag cgctgcacgg gctgtacctc atccacgaga tacacagcgc 7740
gtcccttgag gaggaacttc aggagtggcg gccctggctg gtggttttca tgttcgcctg 7800
cgtgggactc accctggggc tcctcgagga cggagaggct gacgagcccg cgcgggagcc 7860
aggtccagat ctcggcgcgg cgggggcgga gagcgaagac gagggcgcgc agttgggagc 7920
tgtccatggt gtcgcggaga tccaggtccg ggggcagggt tctgaggttg acctcgtaga 7980
ggcgggtgag ggcgtgcttg agatgcagat ggtacttgat ttctacgggt gagttggtgg 8040
tcgtgtccac gcattgcatg agcccgtagc tgcgcggggc cacgaccgtg ccgcggtgcg 8100
cttttagaag cggtgtcgcg gacgcgctcc cggcggcagc ggcggttccg gccccgcggg 8160
caggggcggc agaggcacgt cggcgtggcg ctcgggcagg tcccggtgct gcgccctgag 8220
agcgctggcg tgcgcgacga cgcggcggtt gacatcctgg atctgccgcc tctgcgtgaa 8280
gaccacgggc cccgtgactt tgaacctgaa agacagttca acagaatcaa tctctgcgtc 8340
attgacggcg gcctgacgca ggatctcttg cacgtcgccc gagttgtcct ggtaggcgat 8400
ctcggacatg aactgttcga tctcctcctc ctggagatcg ccgcggcccg cgcgctccac 8460
ggtggcggcg aggtcattgg agatgcgacc catgagctgc gagaaggcgc ccaggccgct 8520
ctcgttccag acgcggctgt agaccacgtc cccgtcggcg tcgcgcgcgc gcatgaccac 8580
ctgcgcgagg ttgagctcca cgtgccgcgc aaagacggcg tagttgcgca ggcgctggaa 8640
gaggtagttg agggtggtgg cgatgtgctc ggtgacgaag aagtacatga tccagcggcg 8700
caggggcatc tcgctgatgt cgccgatggc ttccagcctt tccatggcct cgtagaagtc 8760
cacggcgaag ttgaaaaact gggcgttgcg ggccgagacc gtgagctcgt cttccaggag 8820
ccggatgagt tcggcgatgg tggcgcgcac ctcgcgctcg aaatccccgg gggcctcctc 8880
ctcttcctct tcttccatga cgacctcttc ttctatttct tcctctgggg gcggtggtgg 8940
tggcgggggc cgacgacgac ggcgacgcac cgggagacgg tcgacgaagc gctcgatcat 9000
ctccccgcgg cggcgacgca tggtttcggt gacggcgcga ccccgttcgc gaggacgcag 9060
cgtgaagacg ccgccggtca tctcccggta atggggcggg tccccattgg gcagcgatag 9120
ggcgctgacg atgcatctta tcaattgcgg tgtaggggac gtgagcgcgt cgagatcgac 9180
cggatcggag aatctttcga ggaaagcgtc tagccaatcg cagtcgcaag gtaagctcaa 9240
acacgtagca gccctgcgga cgctgttaga attgcggttg ctgatgatgt aattgaagta 9300
ggcgtttttg aggcggcgga tggtggcgag gaggaccagg tccttgggtc cagcttgctg 9360
gatgcggagc cgctcggcca tgccccaggc ctggccctga caccggctca ggttcttgta 9420
gtagtcatgc atgagcctct caatgtcatc actggctgag gcggagtctt ccatgcgggt 9480
gaccccgacg cccctgagcg gctgcacgag cgccaggtcg gcgacgacgc gctcggcgag 9540
gatggcctgt tgcacgcggg tgagggtgtc ctggaagtcg tccatgtcga cgaagcggtg 9600
ataggccccg gtgttgatgg tgtaggtgca gttggccatg agcgaccagt tgacggtctg 9660
caggcctggc tgcacgacct cggagtacct gagccgcgag aaggcgcgcg agtcgaagac 9720
gtagtcgttg caggtgcgca cgaggtactg gtatccgact aggaagtgcg gcggcggctg 9780
gcggtagagc ggccagcgct gggtggccgg cgcgcccggg gccaggtcct cgagcatgag 9840
gcggtggtag ccgtagaggt agcgggacat ccaggtgatg ccggcggcgg tggtggaggc 9900
gcgcgggaac tcgcggacgc ggttccagat gttgcgcagc ggcaggaaat agtccatggt 9960
cggcacggtc tggccggtga gacgcgcgca gtcattgacg ctctagaggc aaaaacgaaa 10020
gcggttgagc gggctcttcc tccgtagcct ggcggaacgc aaacgggtta ggccgcgtgt 10080
gtaccccggt tcgagtcccc tcgaatcagg ctggagccgc gactaacgtg gtattggcac 10140
tcccgtctcg acccgagccc gatagccgcc aggatacggc ggagagccct ttttgccggc 10200
cgagtggggt cgctagactt gaaagcgacc gaaaaccctg ccgggtagtg gctcgcgccc 10260
gtagtctgga gaagcatcgc cagggttgag tcgcggcaga acccggttcg aggacggccg 10320
cggcgagcgg gacttggtca ccccgccgat ataaagaccc acagccagcc gacttctcca 10380
gttacgggag cgagccccct tttttctttt tgccagatgc atcccgtcct gcgccaaatg 10440
cgtcccaccc ccccggcgac caccgcgacc gcggccgtag caggcgccgg cgctagccag 10500
ccaccacaga cagagatgga cttggaagag ggcgaagggc tggcaagact gggggcgccg 10560
tccccggagc gacatccccg cgtgcagctg cagaaggacg tgcgcccggc gtacgtgcct 10620
acgcagaacc tgttcaggga ccgcagcggg gaggagcccg aggagatgcg cgactgccgg 10680
tttcgggcgg gcagggagct gcgcgagggc ctggaccgcc agcgcgtgct gcgcgacgag 10740
gatttcgagc cgaacgagca gacggggatc agccccgcac gcgcgcacgt ggcggcagcc 10800
aacctggtga cggcctacga gcagacggtg aagcaggagc gcaacttcca aaagagtttc 10860
aacaaccacg tgcgcaccct gatcgcgcgc gaggaggtgg ccctgggcct gatgcacctg 10920
tgggacctgg cggaggccat cgtgcagaac ccggacagca agcctctgac ggcgcagctg 10980
ttcctggtgg tgcagcacag cagggacaac gaggcgttca gggaggcgct gctgaacatc 11040
gccgagcccg agggtcgctg gctgctggag ctgattaaca tcttgcagag catcgtagtg 11100
caggagcgca gcctgagcct ggccgagaag gtggcggcga tcaactactc ggtgctgagc 11160
ctgggcaagt tttacgcgcg caagatttac aagacgccgt acgtgcccat agacaaggag 11220
gtgaagatag acagctttta catgcgcatg gcgctcaagg tgctgacgct gagcgacgac 11280
ctgggcgtgt accgcaacga ccgcatccac aaggccgtga gcacgagccg gcggcgcgag 11340
ctgagcgacc gcgagctgat gctgagtctg cgccgggcgc tggtaggggg cgccgccggc 11400
ggcgaggagt cctacttcga catgggtgcg gacctgcatt ggcagccgag ccggcgcgcc 11460
ttggaggccg cctacggttc agaggacttg gatgaggaag aggaagagga ggaggatgca 11520
cccgctgcgg ggtactgacg cctccgtgat gtgtttttag atgtcccagc aagccccgga 11580
ccccgccata agggcggcgc tgcaaagcca gccgtccggt ctagcatcgg acgactggga 11640
ggccgcgatg caacgcatca tggccctgac gacccgcaac cccgagtcct ttagacaaca 11700
gccgcaggcc aacagactct cggccattct ggaggcggtg gtcccctctc ggaccaaccc 11760
cacgcacgag aaggtgctgg cgatcgtgaa cgcgctggcg gagaacaagg ccatccgtcc 11820
cgacgaggcc gggctggtgt acaacgccct gctggagcgc gtgggccgct acaacagcac 11880
gaacgtgcag tccaacctgg atcggctggt gacggacgtg cgcgaggccg tggcgcagcg 11940
cgagcggttc aagaacgagg gcctgggctc gctggtggcg ctgaacgcct tcctggcgac 12000
gcagccggcg aacgtgccgc gcgggcagga cgattacacc aactttatca gcgcgctgcg 12060
gctgatggtg accgaggtgc cccagagcga ggtgtaccag tctggcccgg actacttttt 12120
ccagacgagc cggcagggct tgcagacggt gaacctgagc caggctttca agaatctgcg 12180
cgggctgtgg ggcgtgcagg cgcccgtggg cgaccggtca acggtgagca gcttgctgac 12240
gcccaactcg cggctgctgc tgctgctgat cgcgcccttc accgacagcg gcagcgtgaa 12300
ccgcaactcg tacctgggcc atctgctgac gctgtaccgc gaggccatag gccaggcgca 12360
ggtggacgag cagaccttcc aggagatcac tagcgtgagc cgcgcgctgg ggcagaacga 12420
caccgacagt ctgagggcca ccctgaactt tttgctgacc aatagacagc agaagatccc 12480
ggcgcagtac gcactgtcgg ccgaggagga aaggattctg agatatgtgc agcagagcgt 12540
agggctgttc ctgatgcagg agggtgccac ccccagcgcc gcgctggaca tgaccgcgcg 12600
caacatggaa cctagcatgt acgccgccaa ccggccgttc atcaataagc tgatggacta 12660
cttgcaccgc gcggcggcca tgaacacgga ctactttacc aacgccatcc tgaacccgca 12720
ctggctcccg ccgccggggt tctacacggg cgagtacgac atgcccgacc ccaacgacgg 12780
gttcctgtgg gacgacgtgg acagcgcggt gttctcgccg acctttcaaa agcgccagga 12840
ggcgccgccg agcgagggcg cggtggggag gagccccttt cctagcttag ggagtttgca 12900
tagcttgccg ggctcggtga acagcggcag ggtgagccgg ccgcgcttgc tgggcgagga 12960
cgagtacctg aacgactcgc tgctgcagcc gccgcgggcc aagaacgcca tggccaataa 13020
cgggatagag agtctggtgg acaaactgaa ccgctggaag acctacgctc aggaccatag 13080
ggacgcgccc gcgccgcggc gacagcgcca cgaccggcag cggggcctgg tgtgggacga 13140
cgaggactcg gccgacgata gcagcgtgtt ggacttgggc gggagcggtg gggtcaaccc 13200
gttcgcgcat ctgcagccca aactggggcg acggatgttt tgaatgaaat aaaactcacc 13260
aaggccatag cgtgcgttct cttccttgtt agagatgagg cgcgcggtgg tgtcttcctc 13320
tcctcctccc tcgtacgaga gcgtgatggc gcaggcgacc ctggaggttc cgtttgtgcc 13380
tccgcggtat atggctccta cggagggcag aaacagcatt cgttactcgg agctggctcc 13440
gcagtacgac accactcgcg tgtacttggt ggacaacaag tcggcggaca tcgcttccct 13500
gaactaccaa aacgaccaca gcaacttcct gaccacggtg gtgcagaaca acgatttcac 13560
ccccgccgag gccagcacgc agacgataaa ttttgacgag cggtcgcggt ggggcggtga 13620
tctgaagacc attctgcaca ctaacatgcc caatgtgaac gagtacatgt tcaccagcaa 13680
gtttaaggcg cgggtgatgg tgtctaggaa gcatccagag ggggtagttg aaacagattt 13740
gagtcaggat aagcttgaat atgagtggtt tgagtttacc ctgcccgagg gaaacttttc 13800
cgagaccatg accatagacc tgatgaacaa cgccatcttg gaaaactact tgcaagtggg 13860
gcggcagaat ggcgtgctgg agagcgatat cggagtcaag tttgacagca gaaatttcaa 13920
gctgggctgg gacccggtga ccaagctggt gatgccaggg gtctacacct acgaggcctt 13980
ccacccggac gtggtgctgc tgccgggctg cggggtggac ttcaccgaga gccgcctgag 14040
caacctcctg ggcattcgca agaagcaacc tttccaagag ggcttcagaa tcatgtatga 14100
ggatctagaa ggtggcaaca tccccgccct ccttgatgtg cccaagtact tggaaagcaa 14160
gaagaaagtt gaagacgaaa ctaaaaatgc agctgcggcc acagccgata caaccactag 14220
gggtgataca tttgcaactc cagcgcaaga gacagcagct gataagaagg tagaagtctt 14280
gcccattgaa aaggatgaga gtggtagaag ttacaacctg atccagggga cccacgacac 14340
gctgtaccgc agttggtacc tgtcctatac ctacggggac cccgagaagg gggtgcagtc 14400
gtggacgctg ctcaccaccc cggacgttac ctgcggcgcg gagcaagtct actggtcact 14460
gccggacctc atgcaagacc ccgtcacctt ccgctccacc cagcaagtca gcaactaccc 14520
cgtggtcggc gccgagctca tgcccttccg cgccaagagc ttttacaacg acctcgccgt 14580
ctactcccag ctcatccgca gctacacctc cctcacccac gtcttcaacc gcttccccga 14640
caaccagatc ctctgccgcc cgcccgcgcc caccatcacc accgtcagtg aaaacgtgcc 14700
tgctctcaca gatcacggga cgctaccgct gcgcagcagt atccgcggag tccagcgagt 14760
gaccgtcact gacgcccgtc gccgcacctg tccctacgtc tacaaggccc tgggcatagt 14820
cgcgccgcgc gtgctttcca gtcgcacctt ctaaaaaaat gtctattctc atctcgccca 14880
gcaataacac cggctggggt cttactagac ccagcaccat gtacggagga gccaagaagc 14940
gctcccagca gcaccccgtc cgcgtccgcg gccacttccg cgctccctgg ggcgcataca 15000
agcgcgggcg gacttccacc gccgccgtgc gcaccaccgt cgacgacgtc atcgactcgg 15060
tggtcgccga cgcgcgcaac tatacccccg ccccctccac cgtggacgcg gtcatcgaca 15120
gcgtggtggc cgacgcgcgc gactatgcca gacgcaagag ccggcggcga cggatcgcca 15180
ggcgccaccg gagcacgccc gccatgcgcg ccgcccgggc tctgctgcgc cgcgccagac 15240
gcacgggccg ccgggccatg atgcgagccg cgcgccgcgc tgccactgca cccacccccg 15300
caggcaggac tcgcagacga gcggccgccg ccgccgctgc ggccatctct agcatgacca 15360
gacccaggcg cggaaacgtg tactgggtgc gcgactccgt cacgggcgtg cgcgtgcccg 15420
tgcgcacccg tcctcctcgt ccctgatcta atgcttgtgt cctcccccgc aagcgacgat 15480
gtcaaagcgc aaaatcaagg aggagatgct ccaggtcgtc gccccggaga tttacggacc 15540
accccaggcg gaccagaaac cccgcaaaat caagcgggtt aaaaaaaagg atgaggtgga 15600
cgagggggca gtagagtttg tgcgcgagtt cgctccgcgg cggcgcgtaa attggaaggg 15660
gcgcagggtg cagcgcgtgt tgcggcccgg cacggcggtg gtgttcacgc ccggcgagcg 15720
gtcctcggtc aggagcaagc gtagctatga cgaggtgtac ggcgacgacg acatcctgga 15780
ccaggcggcg gagcgggcgg gcgagttcgc ctacgggaag cggtcgcgcg aagaggagct 15840
gatctcgctg ccgctggacg aaagcaaccc cacgccgagc ctgaagcccg tgaccctgca 15900
gcaggtgctg ccccaggcgg tgctgctgcc gagccgcggg gtcaagcgcg agggcgagag 15960
catgtacccg accatgcaga tcatggtgcc caagcgccgg cgcgtggagg acgtgctgga 16020
caccgtgaaa atggatgtgg agcccgaggt caaggtgcgc cccatcaagc aggtggcgcc 16080
gggcctgggc gtgcaaaccg tggacattca gatccccacc gacatggatg tcgacaaaaa 16140
accctcgacc agcatcgagg tgcaaaccga cccctggctc ccagcctcca ccgctaccgt 16200
ctccacttct accgccgcca cggctaccga gcctcccagg aggcgaagat ggggcgccgc 16260
cagccggctg atgcccaact acgtgttgca tccttccatc atcccgacgc cgggctaccg 16320
cggcacccgg tactacgcca gccgccggcg cccagccagc aaacgccgcc gccgcaccgc 16380
cacccgccgc cgtctggccc ccgcccgcgt gcgccgcgtg accacgcgcc ggggccgctc 16440
gctcgttctg cccaccgtgc gctaccaccc cagcatcctt taatccgtgt gctgtgatac 16500
tgttgcagag agatggctct cacttgccgc ctgcgcatcc ccgtcccgaa ttaccgagga 16560
agatcccgcc gcaggagagg catggcaggc agcggcctga accgccgccg gcggcgggcc 16620
atgcgcaggc gcctgagtgg cggctttctg cccgcgctca tccccataat cgccgcggcc 16680
attggcacga tcccgggcat agcttccgtt gcgctgcagg cgtcgcagcg ccgttgatgt 16740
gcgaataaag cctctttaga ctctgacaca cctggtcctg tatattttta gaatggaaga 16800
catcaatttt gcgtccctgg ctccgcggca cggcacgcgg ccgttcatgg gcacctggaa 16860
cgagatcggc accagccagc tgaacggggg cgccttcaat tggagcagtg tctggagcgg 16920
gcttaaaaat ttcggctcga cgctccggac ctatgggaac aaggcctgga atagtagcac 16980
ggggcagttg ttgagggaaa agctcaaaga ccagaacttc cagcagaagg tggtggacgg 17040
gctggcctcg ggcattaacg gggtggtgga catcgcgaac caggccgtgc agcgcgagat 17100
aaacagccgc ctggacccgc gaccgcccac ggtggtggag atggaagatg caactcttcc 17160
gccgcccaag ggcgagaagc ggccgcggcc cgacgcggag gagacgatcc tgcaggtgga 17220
cgagccgccc tcgtacgagg aggccgtcaa ggccggcatg cccaccacgc gcatcatcgc 17280
gccgctggcc acgggtgtaa tgaaacccgc cacccttgac ctgcctccac cacccgcgcc 17340
cgctccaccg aaggcaactc cggttgtgca ggcccccccg gtggcgaccg ccgtgcgccg 17400
cgtccccgcc cgccgccagg cccagaactg gcagagcacg ctgcacagta tcgtgggcct 17460
gggagtgaaa agtctgaagc gccgccgatg ctattgagag agaggaaaga ggacactaaa 17520
gggagagctt aacttgtatg tgccttaccg ccagagaacg cgcgaagatg gccaccccct 17580
cgatgatgcc gcagtgggcg tacatgcaca tcgccgggca ggacgcctcg gagtacctga 17640
gcccgggtct ggtgcagttt gcccgcgcca ccgacacgta cttcagcctg ggcaacaagt 17700
ttaggaaccc cacggtggcc ccgacccacg atgtgaccac ggaccggtcc cagcgtctga 17760
cgctgcgctt cgtgcccgtg gatcgcgagg acaccacgta ctcgtacaag gcgcgcttca 17820
ctctggccgt gggcgacaac cgggtgctag acatggccag cacttacttt gacatccgcg 17880
gcgtcctgga ccgcggtccc agcttcaaac cctactcggg cacggcctac aacagcctgg 17940
ctcccaaggg tgcccccaat tccagccagt gggagcaagc aaaaccaggc aatgggggaa 18000
ctatggaaac acacacatat ggtgtggccc caatgggcgg agagaatatt acaaaagatg 18060
gtcttcaaat tggaactgat gctacagcgg atcagaataa accaatttat gctgacaaaa 18120
ctttccagcc agaacctcaa gtaggagaag aaaattggca agaaactgaa agcttttatg 18180
gtggtagggc tcttaaaaaa gacactaaaa tgaaaccatg ctatggatct tttgctagac 18240
ctactaatga gaaaggaggt caggcaaagt tcaaaccagt taatgaagga gaacaaccta 18300
aagatctgga tatagatctg gctttctttg atactcccgg tggcactgtg aatggccaag 18360
atgagtataa agcagacatt gtcatgtaca ctgaaaatgt taatcttgaa acaccagaca 18420
ctcatgtggt ttacaagcca ggcaaggaag atgcaagttc tgaaattaac ctggttcagc 18480
agtccatgcc aaacagaccc aactacattg gctttaggga caactttgta ggtctcatgt 18540
attacaacag caccggaaat atgggtgtgc tggctggtca ggcttctcag ttgaacgctg 18600
tggtcgactt gcaagacaga aacaccgagt tatcttacca gctattgcta gattctctgg 18660
gtgacagaac cagatacttt agcatgtgga actctgcggt ggacagttac gatccagatg 18720
tcaggatcat tgaaaatcac ggtgtggaag atgaacttcc aaactattgc ttcccattgg 18780
atggatctgg cactaacgcc gcctatcaag gtgtaaaagt aaaaaatggt gaagatggtg 18840
atcttgagag cgagtgggaa aatgatgata ctgtggcagc tcgaaatcaa atatgcaaag 18900
gcaatatttt cgccatggag atcaacctgc aggccaacct gtggaagagt tttctgtact 18960
cgaacgtggc cctgtacctg cccgactcct acaagtacac gccggccaac gtcaagctgc 19020
ccgccaacac caacacctac gagtacatga acggccgcgt ggtagccccc tcgctggtgg 19080
acgcctacat caacatcggc gcccgctggt cgttggatcc catggacaac gtcaacccct 19140
tcaaccacca ccgcaatgcg ggcctgcgct accgctccat gctgctgggc aacggccgct 19200
acgtgccctt ccacatccaa gtgccccaaa agttctttgc catcaagaac ctgctcctgc 19260
tcccgggctc ctacacctac gagtggaact tccgcaagga cgtcaacatg atcctgcaga 19320
gttccctcgg caacgacctg cgcgtcgacg gcgcctccgt ccgcttcgac agcgtcaacc 19380
tatacgccac tttcttcccc atggcgcaca acaccgcttc aaccttggaa gccatgctgc 19440
gcaacgacac caacgaccag tccttcaacg actacctctc ggccgccaac atgctctacc 19500
ccatcccggc caaggccacc aacgtgccca tctccatccc atcgcgcaac tgggccgcct 19560
tccgcggctg gagtttcacc cggctcaaga ccaaggaaac tccttccctc ggctcgggtt 19620
tcgaccccta ctttgtctac tcgggctcca tcccctacct cgacgggacc ttctacctca 19680
accacacctt caagaaggtc tccatcatgt tcgactcctc ggtcagctgg cccggcaacg 19740
accggctgct cacgccgaac gagttcgaga tcaagcgcag cgtcgacggg gagggctaca 19800
acgtggccca atgcaacatg accaaggact ggttcctcgt ccagatgctc tcccactaca 19860
acatcggcta ccagggcttc cacgtgcccg agggctacaa ggaccgcatg tactccttct 19920
tccgcaactt ccagcccatg agcaggcagg tggtcgatga gatcaactac aaggactaca 19980
aggccgtcac cctgcccttc cagcacaata actcgggctt caccggctac ctcgcaccca 20040
ccatgcgcca ggggcagccc taccccgcca acttccccta cccgctcatc ggtcagacag 20100
ccgtgccctc cgtcacccag aaaaagttcc tctgcgacag ggtcatgtgg cgcatcccct 20160
tctccagcaa cttcatgtcc atgggcgccc tcaccgacct gggtcagaac atgctctacg 20220
ccaactcggc ccacgcgctc gacatgacct tcgaggtgga ccccatggat gagcccaccc 20280
tcctctatct tctcttcgaa gttttcgacg tggtcagagt acaccagccg caccgcggcg 20340
tcatcgaggc cgtctacctg cgcacgccct tctccgccgg caacgccacc acctaagcat 20400
gagcggctcc agcgaacgag agctcgcggc catcgtgcgc gacctgggct gcgggcccta 20460
ctttttgggc acccacgaca agcgcttccc gggctttctc gccggcgaca agctggcctg 20520
cgccatcgtc aacacggccg gccgcgagac cggaggcgtg cactggctcg ccttcggctg 20580
gaacccgcgc tcgcgcacct gctacatgtt cgaccccttt gggttctcgg accgccggct 20640
caagcagatt tacagcttcg agtacgaggc catgctgcgc cgcagcgccc tggcctcctc 20700
gcccgaccgc tgtctcagcc tcgagcagtc cactcagacc gtgcaggggc ccgactccgc 20760
cgcctgcgga ctcttctgtt gcatgttctt gcatgccttc gtgcactggc ccgaccgacc 20820
catggacgga aaccccacca tgaacttgct gacgggggtg cccaacggca tgctacaatc 20880
gccacaggtg ctgcccaccc tcaggcgcaa ccaggaggaa ctctaccgct tcctcgcgcg 20940
ccactcccct tactttcgct cccaccgcgc cgccatcgaa cacgccaccg cttttgacaa 21000
aatgaaacaa ctgcgtgtat ctcaataaac agcactttta ttttacatgc actggagtat 21060
atgcaagtta tttaaaagtc gaaggggttc tcgcgctcgt cgttgtgcgc cgcgctgggg 21120
agggccacgt tgcggtactg gtacttgggc tgccacttga actcggggat caccagtttg 21180
ggcactgggg tctcggggaa ggtctcgctc cacatgcgcc ggctcatctg cagggcgccc 21240
agcatgtccg gggcggagat cttgaaatcg cagttggggc cggtgctctg cgcgcgcgag 21300
ttgcggtaca cggggttgca gcactggaac accatcagac tggggtactt cacactagcc 21360
agcacgctct tgtcgctgat ctgatccttg tccagatcct cggcgttgct caggccgaac 21420
ggggtcatct tgcacagctg gcgtcccagg aagggcacgc tctgaggctt gtggttacac 21480
tcgcagtgca cgggcatcag catcatcccc gcgccgcgct gcatattcgg gtagagggcc 21540
ttgacaaagg ccgcgatctg cttgaaagct tgctgggcct tggccccctc gctgaaaaac 21600
aggccgcagc tcttcccgct gaactggtta ttcccacacc cggcatcctg cacgcagcag 21660
cgcgcgtcat ggctggtcag ttgcaccacg ctccgtcccc agcggttctg ggtcacctta 21720
gccttgctgg gctgctcctt caacgcgcgc tgcccgttct cgctggtcac atccatctcc 21780
accacgtggt ccttgtggat catcatcgtc ccgtgcagac acttgagctg gccttccacc 21840
tcggtgcagc cgtgatccca cagggcgcaa ccggtgcact cccagttctt gtgcgcaatc 21900
ccgctgtggc tgaagatgta accttgcaac atgcggccca tgatggtgct aaatgctttc 21960
tgggtggtga aggtcagttg catcccgcgg gcctcctcgt tcatccaggt ctggcacatc 22020
ttctggaaga tctcggtctg ctcgggcatg agcttgtaag catcgcgcag gccgctgtcg 22080
acgcggtagc gttccatcag cacgttcatg gtatccatgc ccttctccca ggacgagacc 22140
agaggcagac tcagagggtt gcgtacgttc aggacaccgg gggtcgcggg ctcgacgatg 22200
cgttttccgt ccttgccttc cttcaataga accggcggct ggctgaatcc cactcccacg 22260
atcacggcat cttcctgggg catctcttcg tcggggtcta ccttggtcac atgcttggtc 22320
tttctggctt gcttcttttt tggagggctg tccacgggga gcacgtcctc ctcggaagac 22380
ccggagccca cccgctgata ctttcggcgc ttggtgggca gaggaggtgg cggcgagggg 22440
ctcctctcct gctccggcgg atagcgcgcc gacccgtggc cccggggcgg agtggcctct 22500
cggcccatga accggcgcac gtcctgactg ccgccggcca ttgtttccta ggggaagatg 22560
gaggagcagc cgcgtaagca ggagcaggag gaggacttaa ccacccacga gcaacccaaa 22620
atcgagcagg acctgggctt cgaagagccg gctcgtctag aacccccaca ggatgaacag 22680
gagcacgagc aagacgcagg ccaggaggag accgacgctg ggctcgagca tggctacctg 22740
ggaggagagg aggatgtgct gctgaaacac ctgcagcgcc agtccctcat cctccgggac 22800
gccctggccg accggagcga aacccccctc agcgtcgagg agctgtgtcg ggcctacgag 22860
ctcaacctct tctcgccgcg cgtacccccc aaacgccagc ccaacggcac ctgcgagccc 22920
aacccgcgtc tcaacttcta tcccgtcttt gcggtccccg aagccctcgc cacctatcac 22980
atctttttca agaaccaaaa gatccccgtc tcctgccgcg ccaaccgcac cagcgccgac 23040
gcgctcctcg ctttggggcc cggcgcgcgc atacctgata tcgcttccct ggaagaggtg 23100
cccaagatct tcgaagggct cggtcgggac gagacgcgcg cggcgaacgc tctgaaagaa 23160
acagcagagg aagagggtca cactagcgcc ctggtagagt tggaaggcga caacgccagg 23220
ctggccgtgc tcaagcgcag cgtcgagctt acccacttcg cctaccccgc cgtcaacctc 23280
ccgcccaagg tcatgcgtcg catcatggat cagctcatca tgccccacat cgaggccctc 23340
gatgaaagtc aggagcagcg ccccgaggac gcccggcccg tggtcagcga cgagatgctc 23400
gcgcgctggc tcgggacccg cgacccccag gctttggaac agcggcgcaa actcatgctg 23460
gccgtggtcc tggtcaccct tgagctcgaa tgcatgcgcc gctttttcag cgaccccgag 23520
accctgcgca aggtcgagga gaccctgcac tacactttca ggcacggttt cgtcaggcag 23580
gcctgcaaga tctccaacgt ggagctgacc aacctggtct cctgcctggg gatcctgcac 23640
gagaaccgcc tgggccagac cgtgctccac tctaccctga agggcgaggc gcggcgggac 23700
tatgtccgcg actgcgtctt tctctttctc tgccacacat ggcaagcggc catgggcgtg 23760
tggcagcagt gtctcgagga cgagaaccta aaggagctgg acaagcttct tgctagaaac 23820
cttaaaaagc tgtggacggg cttcgacgag cgcaccgtcg cctcggacct ggccgagatc 23880
gtcttccccg agcgcctgag acagacgctg aaaggcgggc tgcccgactt catgagccag 23940
agcatgttgc aaaactaccg cactttcatt cttgagcgat caggcatcct gcccgccacc 24000
tgcaacgcct tcccctccga ctttgtaccg ctgagctacc gcgagtgtcc cccgccgctg 24060
tggagccact gctacctctt gcagctggcc aactacatcg cctaccactc ggacgtgatc 24120
gaggacgtga gcggcgaggg gctgctcgag tgccactgtc gctgcaacct gtgctccccg 24180
catcgctccc tggtctgcaa cccccagctc ctgagcgaga cccaggtcat cggtaccttc 24240
gagctgcaag gtccgcagga gtccaccgct ccgctgaaac tcacgccggg gttgtggact 24300
tccgcgtacc tgcgcaaatt tgtacccgaa gactaccacg cccatgagat aaagttcttt 24360
gaggaccaat cgcgtccgca gcacgcggat ctcacggcct gcgtcatcac ccagggcgcg 24420
atcctcgccc aattgcacgc catccaaaaa tcccgccaag agtttcttct gaaaaagggt 24480
agaggggtct acctggaccc ccagacgggc gaggtgctca acccgggtct cccccagcat 24540
gccgaggaag aagcaggagc cgctagtgga ggagatggaa gaagaatggg acagccaggc 24600
agaggaggac gaatgggagg aggagacaga ggaggaagaa ttggaagagg tggaagagga 24660
gcaggcaaca gagcagcccg tcgccgcacc atccgcgccg gcagccccgc cggtcacgga 24720
tacaacctcc gctccggtca agcctcctcg tagatgggat caagtgaagg gtgacggtaa 24780
gcacgagcgg cagggctacc gatcatggag ggcccacaaa gccgcgatca tcgcctgctt 24840
gcaagactgc ggggggaaca tcgctttcgc ccgccgctac ctgctcttcc accgcggggt 24900
gaacatcccc cgcaacgtgt tgcattacta ccgtcacctt cacagctaag aaaaagcaag 24960
tcaaaggagt cgccggagga ggaggaggag gcctgaggat cgcggcgaac gagcccttga 25020
ccaccaggga gctgaggaac cggatcttcc ccactcttta tgccattttt cagcagagtc 25080
gaggtcagca gcaagagctc aaagtaaaaa accggtctct gcgctcgctc acccgcagtt 25140
gcttgtacca caaaaacgaa gatcagctgc agcgcactct cgaagacgcc gaggctctgt 25200
tccacaagta ctgcgcgctc actcttaaag actaaggcgc gcccacccgg aaaaaaggcg 25260
ggaattacct catcgccacc atgagcaagg agattcccac cccttacatg tggagctatc 25320
agccccaaat gggcctggcc gcgggcgcct cccaggacta ctccacccgc atgaactggc 25380
tcagtgccgg cccctcgatg atctcacggg tcaacggggt ccgcagtcat cgaaaccaga 25440
tattgttgga gcaggcggcg gtcacctcca cgcccagggc aaagctcaac ccgcgtaatt 25500
ggccctccac cctggtgtat caggaaatcc ccgggccgac taccgtacta cttccgcgtg 25560
acgcactggc cgaagtccgc atgactaact caggtgtcca gctggccggc ggcgcttccc 25620
ggtgcccgct ccgcccacaa tcgggtataa aaaccctggt gatccgaggc agaggcacac 25680
agctcaacga cgagttggtg agctcttcga tcggtctgcg accggacgga gtgttccaac 25740
tagccggagc cgggagatcc tccttcactc ccaaccaggc ctacctgacc ttgcagagca 25800
gctcttcgga gcctcgctcc ggaggcatcg gaaccctcca gtttgtggag gagtttgtgc 25860
cctcggtcta cttcaacccc ttctcgggat cgccaggcct ctacccggac gagttcatac 25920
cgaacttcga cgcagtgaga gaagcggtgg acggctacga ctgaatgtcc catggtgact 25980
cggctgagct cgctcggttg aggcatctgg accactgccg ccgcctgcgc tgcttcgccc 26040
gggagagctg cggactcatc tactttgagt ttcccgagga gcaccccaac ggccctgcac 26100
acggagtgcg gatcaccgta gagggcacca ccgagtctca cctggtcagg ttcttcaccc 26160
agcaaccctt cctggtcgag cgggaccggg gcgccaccac ctacaccgtc tactgcatct 26220
gtccaacccc gaagttgcat gagaattttt gttgtactct ttgtggtgag tttaataaaa 26280
gctaaactct tgcaatactc tggaccttgt cgtcgtcaac tcaacgagac cgtctacctc 26340
accaaccaga ctgaggtaaa actcacctgc agaccacaca agacctatat catctggttc 26400
ttcgagaaca cctcatttgc agtctccaac actcactgca ctagtccatg aactgatgtt 26460
gattaaaagc ccaaaaacca atcagcccct tcccccattt ccccatcccc caattactca 26520
taaaaaataa atcattggaa ttaatcattc aataaagatc acttacttga aatctgaaag 26580
tatgtctctg gtgtagttgt tcagcagcac ctcggtaccc tcctcccagc tctggtactc 26640
cagtccccgg cgggcggcga acttcctcca caccttgaaa gggatgtcaa attcctggtc 26700
cacaattttc attgtcttcc ctctcagatg gcaaagaggc tccgggtgga agatgacttc 26760
aaccccgtct acccctatgg ctacgcgcgg aatcagaata tccccttcct cactcccccc 26820
tttgtctcct ccgatggatt caaaaacttc ccccctgggg tcctgtcact taaactggct 26880
gatccaatca ccatcaacaa tggggatgtc tcacttaagg tgggaggggg acttgctgta 26940
gagcaacaga ctggtaacct aagcgtaaac cctgatgcac ccttgcaagt tgcaagtgat 27000
aagctacagc ttgctctggc tcctccattc gaggtcagag atggaaagct tgctttaaag 27060
gcaggtaatg gattaaaagt actagataat tccattactg gattgactgg attattgaat 27120
acacttgtgg tattaactgg aaggggaata ggaacggagg aattaaaaaa tgacgatggt 27180
gtaacaaaca aaggagtcgg cttgcgtgta agacttggag atgacggcgg gctgacattt 27240
gataaaaagg gtgatttagt agcctggaat aaaaaagatg acaggcgcac cctgtggaca 27300
acccctgaca catctccaaa ttgcaaaatg agtacagaaa aggattctaa acttacgttg 27360
acacttacaa agtgtggaag tcaggttctg ggaaatgtat ctttacttgc agttacaggt 27420
gaatatcatc aaatgactgc tactacaaag aaggatgtaa aaatatcttt actatttgat 27480
gagaatggaa ttctattacc atcttcgtcc cttagcaaag attattggaa ttacagaagt 27540
gatgattcta ttgtatctca aaaatataat aatgcagttc cattcatgcc aaacctgaca 27600
gcttatccaa aaccaagcgc tcaaaatgca aaaaactatt caagaactaa aatcataagt 27660
aatgtctact taggtgctct tacctaccaa cctgtaatta tcactattgc atttaatcag 27720
gaaactgaaa atggatgtgc ttattctata acatttacct tcacttggca aaaagactat 27780
tctgcccaac agtttgatgt tacatctttt accttctcat atcttaccca agagaacaaa 27840
gacaaagact aataaaatgt tttgaactga atttatgaat ctttatttat ttttacacca 27900
gcacgggtag tcagtttccc accaccagcc catttcacag tgtaaacagt cctttctccc 27960
cggctggcct taaaaagcat catatcatgg gtaacagaca tattcttagg tgttatattc 28020
cacacggttt cctgtcgagc caaacgctca tcagtgatat taataaactc cccgggcagc 28080
tcacttaagt tcatgtcgct gtccagctgc tgagccacag gctgctgtcc aacttgcggt 28140
tgcttaacgg gcggcgaagg agaagtccac gcctacatgg gggtagagtc ataatcgtgc 28200
atcaggatag ggcggtggtg ctgcagcagc gcgcgaataa actgctgccg ccgccgctcc 28260
gtcctgcagg aatacaacat ggcagtggtc tcctcagcga tgattcgcac cgcccgcagc 28320
ataaggcgcc ttgtcctccg ggcacagcag cgcaccctga tctcacttaa atcagcacag 28380
taactgcagc acagcaccac aatattgttc aaaatcccac agtgcaaggc gctgtatcca 28440
aagctcatgg cggggaccac agaacccacg tggccatcat accacaagcg caggtagatt 28500
aagtggcgac ccctcataaa cacgctggac ataaacatta cctcttttgg catgttgtaa 28560
ttcaccacct cccggtacca tataaacctc tgattaaaca tggcgccatc caccaccatc 28620
ctaaaccagc tggccaaaac ctgcccgccg gctatacact gcagggaacc gggactggaa 28680
caatgacagt ggagagccca ggactcgtaa ccatggatca tcatgctcgt catgatatca 28740
atgttggcac aacacaggca cacgtgcata cacttcctca ggattacaag ctcctcccgc 28800
gttagaacca tatcccaggg aacaacccat tcctgaatca gcgtaaatcc cacactgcag 28860
ggaagacctc gcacgtaact cacgttgtgc attgtcaaag tgttacattc gggcagcagc 28920
ggatgatcct ccagtatggt agcgcgggtt tctgtctcaa aaggaggtag acgatcccta 28980
ctgtacggag tgcgccgaga caaccgagat cgtgttggtc gtagtgtcat gccaaatgga 29040
acgccggacg tagtcattga aatggattct cttgcgtacc ttgtcgtact tctgccagca 29100
gaaagtggct cgggaacagc agataccttt cctcctgctg tccttccgct gctgacgctc 29160
agtcatccaa ctgaagtaca gccattcccg caggttctcc agcagctcct gtgcatctga 29220
tgaaacaaaa gtcccgtcga tgcggattcc ccttaaaaca tcagccagga cattgtaggc 29280
catcccaatc cagttaatgc atcctgatct atcatgaaga ggaggtgggg gaagaactgg 29340
aagaaccatt tttattccaa gcggtctcga aggacgataa agtgcaagtc acgcaggtga 29400
cagcgttccc cgccgctgtg ctggtggaaa cagacagcca ggtcaaaacc cactctattt 29460
tcaaggtgct cgactgtggc ttcgagcagt ggctctacgc gtacatccag cataagaatc 29520
acattaaagg ctggacctcc atcgatttca tcaatcatca ggttacactc attcaccatc 29580
cccaggtaat tctcattttt ccagccttgg attatttcta caaattgttg gtgtaagtcc 29640
actccgcaca tgtggaaaag ttcccacagc gccccctcca ctttcataat caggcagacc 29700
ttcatattag aaacagatcc tgctgctcca ccacctgcag cgtgttcaaa acaacaagat 29760
tcaatgaggt tctgccctct gccctcagct cacgtctcag cgtcagctgc aaaaagtcac 29820
tcaagtcctc agccactaca gctgacaatt cagagccagg gctaagcgtg ggactggcaa 29880
gcgtgagtga gtactttaat gctccaaagc tagcacccaa aaactgcatg ctggaataag 29940
ctctctttgt gtcaccggtg atgccttcca ataggtgagt gataaagcga ggtagttttt 30000
ctttaatcat ttgagtaata gaaaagtcct ctaaataagt cactaggacc ccaggaacca 30060
caatgtggta gctgacagcg tgtcgctcaa gcatggttag tagagatgag agtctgaaaa 30120
acagaaagca tgcactaaac cagagttgcc agtctcactg aaggaaaaat cactctctcc 30180
agcagcaaag tgcccactgg gtggccctct cggacataca aaaatcgatc cgtgtggtta 30240
aagagcagca cagttagctc ctgtcttctc ccagcaaaga tcacatcgga ctgggttagt 30300
atgcccctgg aatggtagtc attcaaggcc ataaatctgc cttggtagcc attaggaatc 30360
agcacgctca ctctcaagtg aaccaaaacc accccatgcg gaggaatgtg gaaagattct 30420
gggcaaaaaa aggtatatct attgctagtc ccttcctgga cgggagcaat ccctccaggg 30480
ctatctatga aagcatacag agattcagcc atagctcagc ccgcttacca gtagacagag 30540
agcacagcag tacaagcgcc aacagcagcg actgactacc cactgaccca gctccctatt 30600
taaaggcacc ttacactgac gtaatgacca aaggtctaaa aaccccgcca aaaaaacaca 30660
cacgccctgg gtgtttttcg cgaaaacact tccgcgttct cacttcctcg tatcgatttc 30720
gtgactcaac ttccgggttc ccacgttacg tcacttctgc ccttacatgt aactcagccg 30780
tagggcgcca tcttgcccac gtccaaaatg gcttccatgt ccggccacgc ctccgcggcg 30840
accgttagcc gtgcgtcgtg acgtcatttg catcaccgtt tctcgtccaa tcagcgttgg 30900
ctccgcccca aaaccgttaa aattcaaaag ctcatttgca tattaacttt tgtttacttt 30960
gtggggtata ttattgatga tgttaattaa gcaggccatg ctgtccaggc aggtagatga 31020
cgaccatcag ggacagcttc aaggccagca aaaggccagg aaccgtaaaa aggccgcgtt 31080
gctggcgttt ttccataggc tccgcccccc tgacgagcat cacaaaaatc gacgctcaag 31140
tcagaggtgg cgaaacccga caggactata aagataccag gcgtttcccc ctggaagctc 31200
cctcgtgcgc tctcctgttc cgaccctgcc gcttaccgga tacctgtccg cctttctccc 31260
ttcgggaagc gtggcgcttt ctcatagctc acgctgtagg tatctcagtt cggtgtaggt 31320
cgttcgctcc aagctgggct gtgtgcacga accccccgtt cagcccgacc gctgcgcctt 31380
atccggtaac tatcgtcttg agtccaaccc ggtaagacac gacttatcgc cactggcagc 31440
agccactggt aacaggatta gcagagcgag gtatgtaggc ggtgctacag agttcttgaa 31500
gtggtggcct aactacggct acactagaag gacagtattt ggtatctgcg ctctgctgaa 31560
gccagttacc ttcggaaaaa gagttggtag ctcttgatcc ggcaaacaaa ccaccgctgg 31620
tagcggtggt ttttttgttt gcaagcagca gattacgcgc agaaaaaaag gatctcaaga 31680
agatcctttg atcttttcta cggggtctga cgctcagtgg aacgaaaact cacgttaagg 31740
gattttggtc atgagattat caaaaaggat cttcacctag atccttttaa attaaaaatg 31800
aagttttaaa tcaatctaaa gtatatatga gtaaacttgg tctgacagtt accaatgctt 31860
aatcagtgag gcacctatct cagcgatctg tctatttcgt tcatccatag ttgcctgact 31920
ccccgtcgtg tagataacta cgatacggga gggcttacca tctggcccca gtgctgcaat 31980
gataccgcga gacccacgct caccggctcc agatttatca gcaataaacc agccagccgg 32040
aagggccgag cgcagaagtg gtcctgcaac tttatccgcc tccatccagt ctattaattg 32100
ttgccgggaa gctagagtaa gtagttcgcc agttaatagt ttgcgcaacg ttgttgccat 32160
tgctgcaggc atcgtggtgt cacgctcgtc gtttggtatg gcttcattca gctccggttc 32220
ccaacgatca aggcgagtta catgatcccc catgttgtgc aaaaaagcgg ttagctcctt 32280
cggtcctccg atcgttgtca gaagtaagtt ggccgcagtg ttatcactca tggttatggc 32340
agcactgcat aattctctta ctgtcatgcc atccgtaaga tgcttttctg tgactggtga 32400
gtactcaacc aagtcattct gagaatagtg tatgcggcga ccgagttgct cttgcccggc 32460
gtcaacacgg gataataccg cgccacatag cagaacttta aaagtgctca tcattggaaa 32520
acgttcttcg gggcgaaaac tctcaaggat cttaccgctg ttgagatcca gttcgatgta 32580
acccactcgt gcacccaact gatcttcagc atcttttact ttcaccagcg tttctgggtg 32640
agcaaaaaca ggaaggcaaa atgccgcaaa aaagggaata agggcgacac ggaaatgttg 32700
aatactcata ctcttccttt ttcaatatta ttgaagcatt tatcagggtt attgtctcat 32760
gagcggatac atatttgaat gtatttagaa aaataaacaa ataggggttc cgcgcacatt 32820
tccccgaaaa gtgccacctg acgtctaaga aaccattatt atcatgacat taacctataa 32880
aaataggcgt atcacgaggc cctttcgtct tcaagaattg gtcgatggca aacagctatt 32940
atgggtatta tgggttcgaa ttaattaatc ga 32972
<210> 23
<211> 2862
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVR5六邻体
<400> 23
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aatccttgcg aatgggatga agctgctact 420
gctcttgaaa taaacctaga agaagaggac gatgacaacg aagacgaagt agacgagcaa 480
gctgagcagc aaaaaactca cgtatttggg caggcgcctt attctggtat aaatattaca 540
aaggagggta ttcaaatagg tgtcgaaggt caaacaccta aatatgccga taaaactttc 600
cagccagaac ctcaaatagg agaatctcag tggtacgaaa ctgaaattaa tcatgcagct 660
gggagagtcc ttaaaaagga cactaaaatg aaaccatgct atggatcttt tgctagacct 720
actaatgaga aaggaggtca ggcaaagttc aaaccagtta atgaaggaga acaacctaaa 780
gatctggata tagatatgca atttttctca actactgagg cgaccgcagg caatggtgat 840
aacttgactc ctaaagtggt attgtacact gaaaatgtta atcttgaaac accagacact 900
catgtggttt acaagcccac tattaaggaa ggtaactcac gagaactaat gggccagcag 960
tccatgccaa acagacccaa ctacattggc tttagggaca actttgtagg tctcatgtat 1020
tacaacagca ccggaaatat gggtgtgctg gctggtcagg cttctcagtt gaacgctgtg 1080
gtcgacttgc aagacagaaa caccgagtta tcttaccagc tattgctaga ttctctgggt 1140
gacagaacca gatactttag catgtggaac tctgcggtgg acagttacga tccagatgtc 1200
aggatcattg aaaatcacgg tgtggaagat gaacttccaa actattgctt cccattggga 1260
ggtgtgatta atacagagac tcttaccaag gtaaaaccta aaacaggtca ggaaaatgga 1320
tgggaaaaag atgctacaga attttcagat aaaaatgaaa taagagttgg aaataatttt 1380
gccatggaga tcaacctgca ggccaacctg tggaagagtt ttctgtactc gaacgtggcc 1440
ctgtacctgc ccgactccta caagtacacg ccggccaacg tcaagctgcc cgccaacacc 1500
aacacctacg agtacatgaa cggccgcgtg gtagccccct cgctggtgga cgcctacatc 1560
aacatcggcg cccgctggtc gttggatccc atggacaacg tcaacccctt caaccaccac 1620
cgcaatgcgg gcctgcgcta ccgctccatg ctgctgggca acggccgcta cgtgcccttc 1680
cacatccaag tgccccaaaa gttctttgcc atcaagaacc tgctcctgct cccgggctcc 1740
tacacctacg agtggaactt ccgcaaggac gtcaacatga tcctgcagag ttccctcggc 1800
aacgacctgc gcgtcgacgg cgcctccgtc cgcttcgaca gcgtcaacct atacgccact 1860
ttcttcccca tggcgcacaa caccgcttca accttggaag ccatgctgcg caacgacacc 1920
aacgaccagt ccttcaacga ctacctctcg gccgccaaca tgctctaccc catcccggcc 1980
aaggccacca acgtgcccat ctccatccca tcgcgcaact gggccgcctt ccgcggctgg 2040
agtttcaccc ggctcaagac caaggaaact ccttccctcg gctcgggttt cgacccctac 2100
tttgtctact cgggctccat cccctacctc gacgggacct tctacctcaa ccacaccttc 2160
aagaaggtct ccatcatgtt cgactcctcg gtcagctggc ccggcaacga ccggctgctc 2220
acgccgaacg agttcgagat caagcgcagc gtcgacgggg agggctacaa cgtggcccaa 2280
tgcaacatga ccaaggactg gttcctcgtc cagatgctct cccactacaa catcggctac 2340
cagggcttcc acgtgcccga gggctacaag gaccgcatgt actccttctt ccgcaacttc 2400
cagcccatga gcaggcaggt ggtcgatgag atcaactaca aggactacaa ggccgtcacc 2460
ctgcccttcc agcacaataa ctcgggcttc accggctacc tcgcacccac catgcgccag 2520
gggcagccct accccgccaa cttcccctac ccgctcatcg gtcagacagc cgtgccctcc 2580
gtcacccaga aaaagttcct ctgcgacagg gtcatgtggc gcatcccctt ctccagcaac 2640
ttcatgtcca tgggcgccct caccgacctg ggtcagaaca tgctctacgc caactcggcc 2700
cacgcgctcg acatgacctt cgaggtggac cccatggatg agcccaccct cctctatctt 2760
ctcttcgaag ttttcgacgt ggtcagagta caccagccgc accgcggcgt catcgaggcc 2820
gtctacctgc gcacgccctt ctccgccggc aacgccacca cc 2862
<210> 24
<211> 2856
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVR35
<400> 24
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aatgcatctc aatggattgc aaaaggcgta 420
ccaactgcag cagccgcagg caatggtgaa gaagaacatg aaacagagga gaaaactgct 480
acttacactt ttgccaatgc tcctgtaaaa gccgaggctc aaattacaaa agagggctta 540
ccaataggtt tggagatttc agctgaaaac gaatctaaac ccatctatgc agataaaact 600
ttccagccag aacctcaagt gggagatgaa acttggactg acctagacgg aaaaaccgaa 660
gagtatggag gcagggctct aaagcctgac actaaaatga aaccatgcta tggatctttt 720
gctagaccta ctaatgagaa aggaggtcag gcaaagttca aaccagttaa tgaaggagaa 780
caacctaaag atctggatat agatatggaa ttttttgata actcatcgca aagaacaaac 840
ttcagtccta aaattgtcat gtacactgaa aatgttaatc ttgaaacacc agacactcat 900
gtggtttaca agcctggaac agaagacaca agttccgaag ctaatttggg acagcagtcc 960
atgccaaaca gacccaacta cattggcttt agggacaact ttgtaggtct catgtattac 1020
aacagcaccg gaaatatggg tgtgctggct ggtcaggctt ctcagttgaa cgctgtggtc 1080
gacttgcaag acagaaacac cgagttatct taccagctat tgctagattc tctgggtgac 1140
agaaccagat actttagcat gtggaactct gcggtggaca gttacgatcc agatgtcagg 1200
atcattgaaa atcacggtgt ggaagatgaa cttccaaact attgcttccc attggacggc 1260
ataggtgttc caacaaccag ttacaaatca atagttccaa atggagaaga taataataat 1320
tggaaagaac ctgaagtaaa tggaacaagt gagatcggac agggtaattt gtttgccatg 1380
gagatcaacc tgcaggccaa cctgtggaag agttttctgt actcgaacgt ggccctgtac 1440
ctgcccgact cctacaagta cacgccggcc aacgtcaagc tgcccgccaa caccaacacc 1500
tacgagtaca tgaacggccg cgtggtagcc ccctcgctgg tggacgccta catcaacatc 1560
ggcgcccgct ggtcgttgga tcccatggac aacgtcaacc ccttcaacca ccaccgcaat 1620
gcgggcctgc gctaccgctc catgctgctg ggcaacggcc gctacgtgcc cttccacatc 1680
caagtgcccc aaaagttctt tgccatcaag aacctgctcc tgctcccggg ctcctacacc 1740
tacgagtgga acttccgcaa ggacgtcaac atgatcctgc agagttccct cggcaacgac 1800
ctgcgcgtcg acggcgcctc cgtccgcttc gacagcgtca acctatacgc cactttcttc 1860
cccatggcgc acaacaccgc ttcaaccttg gaagccatgc tgcgcaacga caccaacgac 1920
cagtccttca acgactacct ctcggccgcc aacatgctct accccatccc ggccaaggcc 1980
accaacgtgc ccatctccat cccatcgcgc aactgggccg ccttccgcgg ctggagtttc 2040
acccggctca agaccaagga aactccttcc ctcggctcgg gtttcgaccc ctactttgtc 2100
tactcgggct ccatccccta cctcgacggg accttctacc tcaaccacac cttcaagaag 2160
gtctccatca tgttcgactc ctcggtcagc tggcccggca acgaccggct gctcacgccg 2220
aacgagttcg agatcaagcg cagcgtcgac ggggagggct acaacgtggc ccaatgcaac 2280
atgaccaagg actggttcct cgtccagatg ctctcccact acaacatcgg ctaccagggc 2340
ttccacgtgc ccgagggcta caaggaccgc atgtactcct tcttccgcaa cttccagccc 2400
atgagcaggc aggtggtcga tgagatcaac tacaaggact acaaggccgt caccctgccc 2460
ttccagcaca ataactcggg cttcaccggc tacctcgcac ccaccatgcg ccaggggcag 2520
ccctaccccg ccaacttccc ctacccgctc atcggtcaga cagccgtgcc ctccgtcacc 2580
cagaaaaagt tcctctgcga cagggtcatg tggcgcatcc ccttctccag caacttcatg 2640
tccatgggcg ccctcaccga cctgggtcag aacatgctct acgccaactc ggcccacgcg 2700
ctcgacatga ccttcgaggt ggaccccatg gatgagccca ccctcctcta tcttctcttc 2760
gaagttttcg acgtggtcag agtacaccag ccgcaccgcg gcgtcatcga ggccgtctac 2820
ctgcgcacgc ccttctccgc cggcaacgcc accacc 2856
<210> 25
<211> 2787
<212> DNA
<213> 人工序列
<220>
<223> Ad26HVR52
<400> 25
atggccaccc cctcgatgat gccgcagtgg gcgtacatgc acatcgccgg gcaggacgcc 60
tcggagtacc tgagcccggg tctggtgcag tttgcccgcg ccaccgacac gtacttcagc 120
ctgggcaaca agtttaggaa ccccacggtg gccccgaccc acgatgtgac cacggaccgg 180
tcccagcgtc tgacgctgcg cttcgtgccc gtggatcgcg aggacaccac gtactcgtac 240
aaggcgcgct tcactctggc cgtgggcgac aaccgggtgc tagacatggc cagcacttac 300
tttgacatcc gcggcgtcct ggaccgcggt cccagcttca aaccctactc gggcacggcc 360
tacaacagcc tggctcccaa gggtgccccc aattccgtag agtggccgga taatactaaa 420
acaaaagtga gagcccaagc accgtttgta agcgacgaaa tcactaaaga cggcataaag 480
gttggaacag ataccgcaac cacccaacaa agcatttacg ccgataaaac tttccagcca 540
gaacctcaag taggggaaac acagtggaac agcgatgtag gcactaatga taaagtggca 600
ggaagagttt taaagaaaga cactaaaatg aaaccatgct atggatcttt tgctagacct 660
actaatgaga aaggaggtca ggcaaagttc aaaccagtta atgaaggaga acaacctaaa 720
gatctggata tagatatgca gttttttgcc accactgcag ccaatacaac accaaaagct 780
gttctttaca ctgaaaatgt taatcttgaa acaccagaca ctcatgtggt ttacaagccc 840
actgtgacag agggaacgac aagtgccgaa gctttgctag cgcagcagtc catgccaaac 900
agacccaact acattggctt tagggacaac tttgtaggtc tcatgtatta caacagcacc 960
ggaaatatgg gtgtgctggc tggtcaggct tctcagttga acgctgtggt cgacttgcaa 1020
gacagaaaca ccgagttatc ttaccagcta ttgctagatt ctctgggtga cagaaccaga 1080
tactttagca tgtggaactc tgcggtggac agttacgatc cagatgtcag gatcattgaa 1140
aatcacggtg tggaagatga acttccaaac tattgcttcc cattgggagg aatggcggtc 1200
acagacacct actcccccat aaaatccaat aatggaagcg gttggcaagt agacaacgat 1260
acgtttgccg acaggggggt ggaaataggc tcgggaaaca tgttcgccat ggagatcaac 1320
ctgcaggcca acctgtggaa gagttttctg tactcgaacg tggccctgta cctgcccgac 1380
tcctacaagt acacgccggc caacgtcaag ctgcccgcca acaccaacac ctacgagtac 1440
atgaacggcc gcgtggtagc cccctcgctg gtggacgcct acatcaacat cggcgcccgc 1500
tggtcgttgg atcccatgga caacgtcaac cccttcaacc accaccgcaa tgcgggcctg 1560
cgctaccgct ccatgctgct gggcaacggc cgctacgtgc ccttccacat ccaagtgccc 1620
caaaagttct ttgccatcaa gaacctgctc ctgctcccgg gctcctacac ctacgagtgg 1680
aacttccgca aggacgtcaa catgatcctg cagagttccc tcggcaacga cctgcgcgtc 1740
gacggcgcct ccgtccgctt cgacagcgtc aacctatacg ccactttctt ccccatggcg 1800
cacaacaccg cttcaacctt ggaagccatg ctgcgcaacg acaccaacga ccagtccttc 1860
aacgactacc tctcggccgc caacatgctc taccccatcc cggccaaggc caccaacgtg 1920
cccatctcca tcccatcgcg caactgggcc gccttccgcg gctggagttt cacccggctc 1980
aagaccaagg aaactccttc cctcggctcg ggtttcgacc cctactttgt ctactcgggc 2040
tccatcccct acctcgacgg gaccttctac ctcaaccaca ccttcaagaa ggtctccatc 2100
atgttcgact cctcggtcag ctggcccggc aacgaccggc tgctcacgcc gaacgagttc 2160
gagatcaagc gcagcgtcga cggggagggc tacaacgtgg cccaatgcaa catgaccaag 2220
gactggttcc tcgtccagat gctctcccac tacaacatcg gctaccaggg cttccacgtg 2280
cccgagggct acaaggaccg catgtactcc ttcttccgca acttccagcc catgagcagg 2340
caggtggtcg atgagatcaa ctacaaggac tacaaggccg tcaccctgcc cttccagcac 2400
aataactcgg gcttcaccgg ctacctcgca cccaccatgc gccaggggca gccctacccc 2460
gccaacttcc cctacccgct catcggtcag acagccgtgc cctccgtcac ccagaaaaag 2520
ttcctctgcg acagggtcat gtggcgcatc cccttctcca gcaacttcat gtccatgggc 2580
gccctcaccg acctgggtca gaacatgctc tacgccaact cggcccacgc gctcgacatg 2640
accttcgagg tggaccccat ggatgagccc accctcctct atcttctctt cgaagttttc 2700
gacgtggtca gagtacacca gccgcaccgc ggcgtcatcg aggccgtcta cctgcgcacg 2760
cccttctccg ccggcaacgc caccacc 2787
<210> 26
<211> 954
<212> PRT
<213> 人工序列
<220>
<223> Ad26HVR5
<400> 26
Met Ala Thr Pro Ser Met Met Pro Gln Trp Ala Tyr Met His Ile Ala
1 5 10 15
Gly Gln Asp Ala Ser Glu Tyr Leu Ser Pro Gly Leu Val Gln Phe Ala
20 25 30
Arg Ala Thr Asp Thr Tyr Phe Ser Leu Gly Asn Lys Phe Arg Asn Pro
35 40 45
Thr Val Ala Pro Thr His Asp Val Thr Thr Asp Arg Ser Gln Arg Leu
50 55 60
Thr Leu Arg Phe Val Pro Val Asp Arg Glu Asp Thr Thr Tyr Ser Tyr
65 70 75 80
Lys Ala Arg Phe Thr Leu Ala Val Gly Asp Asn Arg Val Leu Asp Met
85 90 95
Ala Ser Thr Tyr Phe Asp Ile Arg Gly Val Leu Asp Arg Gly Pro Ser
100 105 110
Phe Lys Pro Tyr Ser Gly Thr Ala Tyr Asn Ser Leu Ala Pro Lys Gly
115 120 125
Ala Pro Asn Pro Cys Glu Trp Asp Glu Ala Ala Thr Ala Leu Glu Ile
130 135 140
Asn Leu Glu Glu Glu Asp Asp Asp Asn Glu Asp Glu Val Asp Glu Gln
145 150 155 160
Ala Glu Gln Gln Lys Thr His Val Phe Gly Gln Ala Pro Tyr Ser Gly
165 170 175
Ile Asn Ile Thr Lys Glu Gly Ile Gln Ile Gly Val Glu Gly Gln Thr
180 185 190
Pro Lys Tyr Ala Asp Lys Thr Phe Gln Pro Glu Pro Gln Ile Gly Glu
195 200 205
Ser Gln Trp Tyr Glu Thr Glu Ile Asn His Ala Ala Gly Arg Val Leu
210 215 220
Lys Lys Asp Thr Lys Met Lys Pro Cys Tyr Gly Ser Phe Ala Arg Pro
225 230 235 240
Thr Asn Glu Lys Gly Gly Gln Ala Lys Phe Lys Pro Val Asn Glu Gly
245 250 255
Glu Gln Pro Lys Asp Leu Asp Ile Asp Met Gln Phe Phe Ser Thr Thr
260 265 270
Glu Ala Thr Ala Gly Asn Gly Asp Asn Leu Thr Pro Lys Val Val Leu
275 280 285
Tyr Thr Glu Asn Val Asn Leu Glu Thr Pro Asp Thr His Val Val Tyr
290 295 300
Lys Pro Thr Ile Lys Glu Gly Asn Ser Arg Glu Leu Met Gly Gln Gln
305 310 315 320
Ser Met Pro Asn Arg Pro Asn Tyr Ile Gly Phe Arg Asp Asn Phe Val
325 330 335
Gly Leu Met Tyr Tyr Asn Ser Thr Gly Asn Met Gly Val Leu Ala Gly
340 345 350
Gln Ala Ser Gln Leu Asn Ala Val Val Asp Leu Gln Asp Arg Asn Thr
355 360 365
Glu Leu Ser Tyr Gln Leu Leu Leu Asp Ser Leu Gly Asp Arg Thr Arg
370 375 380
Tyr Phe Ser Met Trp Asn Ser Ala Val Asp Ser Tyr Asp Pro Asp Val
385 390 395 400
Arg Ile Ile Glu Asn His Gly Val Glu Asp Glu Leu Pro Asn Tyr Cys
405 410 415
Phe Pro Leu Gly Gly Val Ile Asn Thr Glu Thr Leu Thr Lys Val Lys
420 425 430
Pro Lys Thr Gly Gln Glu Asn Gly Trp Glu Lys Asp Ala Thr Glu Phe
435 440 445
Ser Asp Lys Asn Glu Ile Arg Val Gly Asn Asn Phe Ala Met Glu Ile
450 455 460
Asn Leu Gln Ala Asn Leu Trp Lys Ser Phe Leu Tyr Ser Asn Val Ala
465 470 475 480
Leu Tyr Leu Pro Asp Ser Tyr Lys Tyr Thr Pro Ala Asn Val Lys Leu
485 490 495
Pro Ala Asn Thr Asn Thr Tyr Glu Tyr Met Asn Gly Arg Val Val Ala
500 505 510
Pro Ser Leu Val Asp Ala Tyr Ile Asn Ile Gly Ala Arg Trp Ser Leu
515 520 525
Asp Pro Met Asp Asn Val Asn Pro Phe Asn His His Arg Asn Ala Gly
530 535 540
Leu Arg Tyr Arg Ser Met Leu Leu Gly Asn Gly Arg Tyr Val Pro Phe
545 550 555 560
His Ile Gln Val Pro Gln Lys Phe Phe Ala Ile Lys Asn Leu Leu Leu
565 570 575
Leu Pro Gly Ser Tyr Thr Tyr Glu Trp Asn Phe Arg Lys Asp Val Asn
580 585 590
Met Ile Leu Gln Ser Ser Leu Gly Asn Asp Leu Arg Val Asp Gly Ala
595 600 605
Ser Val Arg Phe Asp Ser Val Asn Leu Tyr Ala Thr Phe Phe Pro Met
610 615 620
Ala His Asn Thr Ala Ser Thr Leu Glu Ala Met Leu Arg Asn Asp Thr
625 630 635 640
Asn Asp Gln Ser Phe Asn Asp Tyr Leu Ser Ala Ala Asn Met Leu Tyr
645 650 655
Pro Ile Pro Ala Lys Ala Thr Asn Val Pro Ile Ser Ile Pro Ser Arg
660 665 670
Asn Trp Ala Ala Phe Arg Gly Trp Ser Phe Thr Arg Leu Lys Thr Lys
675 680 685
Glu Thr Pro Ser Leu Gly Ser Gly Phe Asp Pro Tyr Phe Val Tyr Ser
690 695 700
Gly Ser Ile Pro Tyr Leu Asp Gly Thr Phe Tyr Leu Asn His Thr Phe
705 710 715 720
Lys Lys Val Ser Ile Met Phe Asp Ser Ser Val Ser Trp Pro Gly Asn
725 730 735
Asp Arg Leu Leu Thr Pro Asn Glu Phe Glu Ile Lys Arg Ser Val Asp
740 745 750
Gly Glu Gly Tyr Asn Val Ala Gln Cys Asn Met Thr Lys Asp Trp Phe
755 760 765
Leu Val Gln Met Leu Ser His Tyr Asn Ile Gly Tyr Gln Gly Phe His
770 775 780
Val Pro Glu Gly Tyr Lys Asp Arg Met Tyr Ser Phe Phe Arg Asn Phe
785 790 795 800
Gln Pro Met Ser Arg Gln Val Val Asp Glu Ile Asn Tyr Lys Asp Tyr
805 810 815
Lys Ala Val Thr Leu Pro Phe Gln His Asn Asn Ser Gly Phe Thr Gly
820 825 830
Tyr Leu Ala Pro Thr Met Arg Gln Gly Gln Pro Tyr Pro Ala Asn Phe
835 840 845
Pro Tyr Pro Leu Ile Gly Gln Thr Ala Val Pro Ser Val Thr Gln Lys
850 855 860
Lys Phe Leu Cys Asp Arg Val Met Trp Arg Ile Pro Phe Ser Ser Asn
865 870 875 880
Phe Met Ser Met Gly Ala Leu Thr Asp Leu Gly Gln Asn Met Leu Tyr
885 890 895
Ala Asn Ser Ala His Ala Leu Asp Met Thr Phe Glu Val Asp Pro Met
900 905 910
Asp Glu Pro Thr Leu Leu Tyr Leu Leu Phe Glu Val Phe Asp Val Val
915 920 925
Arg Val His Gln Pro His Arg Gly Val Ile Glu Ala Val Tyr Leu Arg
930 935 940
Thr Pro Phe Ser Ala Gly Asn Ala Thr Thr
945 950
<210> 27
<211> 952
<212> PRT
<213> 人工序列
<220>
<223> Ad26HVR35
<400> 27
Met Ala Thr Pro Ser Met Met Pro Gln Trp Ala Tyr Met His Ile Ala
1 5 10 15
Gly Gln Asp Ala Ser Glu Tyr Leu Ser Pro Gly Leu Val Gln Phe Ala
20 25 30
Arg Ala Thr Asp Thr Tyr Phe Ser Leu Gly Asn Lys Phe Arg Asn Pro
35 40 45
Thr Val Ala Pro Thr His Asp Val Thr Thr Asp Arg Ser Gln Arg Leu
50 55 60
Thr Leu Arg Phe Val Pro Val Asp Arg Glu Asp Thr Thr Tyr Ser Tyr
65 70 75 80
Lys Ala Arg Phe Thr Leu Ala Val Gly Asp Asn Arg Val Leu Asp Met
85 90 95
Ala Ser Thr Tyr Phe Asp Ile Arg Gly Val Leu Asp Arg Gly Pro Ser
100 105 110
Phe Lys Pro Tyr Ser Gly Thr Ala Tyr Asn Ser Leu Ala Pro Lys Gly
115 120 125
Ala Pro Asn Ala Ser Gln Trp Ile Ala Lys Gly Val Pro Thr Ala Ala
130 135 140
Ala Ala Gly Asn Gly Glu Glu Glu His Glu Thr Glu Glu Lys Thr Ala
145 150 155 160
Thr Tyr Thr Phe Ala Asn Ala Pro Val Lys Ala Glu Ala Gln Ile Thr
165 170 175
Lys Glu Gly Leu Pro Ile Gly Leu Glu Ile Ser Ala Glu Asn Glu Ser
180 185 190
Lys Pro Ile Tyr Ala Asp Lys Thr Phe Gln Pro Glu Pro Gln Val Gly
195 200 205
Asp Glu Thr Trp Thr Asp Leu Asp Gly Lys Thr Glu Glu Tyr Gly Gly
210 215 220
Arg Ala Leu Lys Pro Asp Thr Lys Met Lys Pro Cys Tyr Gly Ser Phe
225 230 235 240
Ala Arg Pro Thr Asn Glu Lys Gly Gly Gln Ala Lys Phe Lys Pro Val
245 250 255
Asn Glu Gly Glu Gln Pro Lys Asp Leu Asp Ile Asp Met Glu Phe Phe
260 265 270
Asp Asn Ser Ser Gln Arg Thr Asn Phe Ser Pro Lys Ile Val Met Tyr
275 280 285
Thr Glu Asn Val Asn Leu Glu Thr Pro Asp Thr His Val Val Tyr Lys
290 295 300
Pro Gly Thr Glu Asp Thr Ser Ser Glu Ala Asn Leu Gly Gln Gln Ser
305 310 315 320
Met Pro Asn Arg Pro Asn Tyr Ile Gly Phe Arg Asp Asn Phe Val Gly
325 330 335
Leu Met Tyr Tyr Asn Ser Thr Gly Asn Met Gly Val Leu Ala Gly Gln
340 345 350
Ala Ser Gln Leu Asn Ala Val Val Asp Leu Gln Asp Arg Asn Thr Glu
355 360 365
Leu Ser Tyr Gln Leu Leu Leu Asp Ser Leu Gly Asp Arg Thr Arg Tyr
370 375 380
Phe Ser Met Trp Asn Ser Ala Val Asp Ser Tyr Asp Pro Asp Val Arg
385 390 395 400
Ile Ile Glu Asn His Gly Val Glu Asp Glu Leu Pro Asn Tyr Cys Phe
405 410 415
Pro Leu Asp Gly Ile Gly Val Pro Thr Thr Ser Tyr Lys Ser Ile Val
420 425 430
Pro Asn Gly Glu Asp Asn Asn Asn Trp Lys Glu Pro Glu Val Asn Gly
435 440 445
Thr Ser Glu Ile Gly Gln Gly Asn Leu Phe Ala Met Glu Ile Asn Leu
450 455 460
Gln Ala Asn Leu Trp Lys Ser Phe Leu Tyr Ser Asn Val Ala Leu Tyr
465 470 475 480
Leu Pro Asp Ser Tyr Lys Tyr Thr Pro Ala Asn Val Lys Leu Pro Ala
485 490 495
Asn Thr Asn Thr Tyr Glu Tyr Met Asn Gly Arg Val Val Ala Pro Ser
500 505 510
Leu Val Asp Ala Tyr Ile Asn Ile Gly Ala Arg Trp Ser Leu Asp Pro
515 520 525
Met Asp Asn Val Asn Pro Phe Asn His His Arg Asn Ala Gly Leu Arg
530 535 540
Tyr Arg Ser Met Leu Leu Gly Asn Gly Arg Tyr Val Pro Phe His Ile
545 550 555 560
Gln Val Pro Gln Lys Phe Phe Ala Ile Lys Asn Leu Leu Leu Leu Pro
565 570 575
Gly Ser Tyr Thr Tyr Glu Trp Asn Phe Arg Lys Asp Val Asn Met Ile
580 585 590
Leu Gln Ser Ser Leu Gly Asn Asp Leu Arg Val Asp Gly Ala Ser Val
595 600 605
Arg Phe Asp Ser Val Asn Leu Tyr Ala Thr Phe Phe Pro Met Ala His
610 615 620
Asn Thr Ala Ser Thr Leu Glu Ala Met Leu Arg Asn Asp Thr Asn Asp
625 630 635 640
Gln Ser Phe Asn Asp Tyr Leu Ser Ala Ala Asn Met Leu Tyr Pro Ile
645 650 655
Pro Ala Lys Ala Thr Asn Val Pro Ile Ser Ile Pro Ser Arg Asn Trp
660 665 670
Ala Ala Phe Arg Gly Trp Ser Phe Thr Arg Leu Lys Thr Lys Glu Thr
675 680 685
Pro Ser Leu Gly Ser Gly Phe Asp Pro Tyr Phe Val Tyr Ser Gly Ser
690 695 700
Ile Pro Tyr Leu Asp Gly Thr Phe Tyr Leu Asn His Thr Phe Lys Lys
705 710 715 720
Val Ser Ile Met Phe Asp Ser Ser Val Ser Trp Pro Gly Asn Asp Arg
725 730 735
Leu Leu Thr Pro Asn Glu Phe Glu Ile Lys Arg Ser Val Asp Gly Glu
740 745 750
Gly Tyr Asn Val Ala Gln Cys Asn Met Thr Lys Asp Trp Phe Leu Val
755 760 765
Gln Met Leu Ser His Tyr Asn Ile Gly Tyr Gln Gly Phe His Val Pro
770 775 780
Glu Gly Tyr Lys Asp Arg Met Tyr Ser Phe Phe Arg Asn Phe Gln Pro
785 790 795 800
Met Ser Arg Gln Val Val Asp Glu Ile Asn Tyr Lys Asp Tyr Lys Ala
805 810 815
Val Thr Leu Pro Phe Gln His Asn Asn Ser Gly Phe Thr Gly Tyr Leu
820 825 830
Ala Pro Thr Met Arg Gln Gly Gln Pro Tyr Pro Ala Asn Phe Pro Tyr
835 840 845
Pro Leu Ile Gly Gln Thr Ala Val Pro Ser Val Thr Gln Lys Lys Phe
850 855 860
Leu Cys Asp Arg Val Met Trp Arg Ile Pro Phe Ser Ser Asn Phe Met
865 870 875 880
Ser Met Gly Ala Leu Thr Asp Leu Gly Gln Asn Met Leu Tyr Ala Asn
885 890 895
Ser Ala His Ala Leu Asp Met Thr Phe Glu Val Asp Pro Met Asp Glu
900 905 910
Pro Thr Leu Leu Tyr Leu Leu Phe Glu Val Phe Asp Val Val Arg Val
915 920 925
His Gln Pro His Arg Gly Val Ile Glu Ala Val Tyr Leu Arg Thr Pro
930 935 940
Phe Ser Ala Gly Asn Ala Thr Thr
945 950
<210> 28
<211> 929
<212> PRT
<213> 人工序列
<220>
<223> Ad26HVR52
<400> 28
Met Ala Thr Pro Ser Met Met Pro Gln Trp Ala Tyr Met His Ile Ala
1 5 10 15
Gly Gln Asp Ala Ser Glu Tyr Leu Ser Pro Gly Leu Val Gln Phe Ala
20 25 30
Arg Ala Thr Asp Thr Tyr Phe Ser Leu Gly Asn Lys Phe Arg Asn Pro
35 40 45
Thr Val Ala Pro Thr His Asp Val Thr Thr Asp Arg Ser Gln Arg Leu
50 55 60
Thr Leu Arg Phe Val Pro Val Asp Arg Glu Asp Thr Thr Tyr Ser Tyr
65 70 75 80
Lys Ala Arg Phe Thr Leu Ala Val Gly Asp Asn Arg Val Leu Asp Met
85 90 95
Ala Ser Thr Tyr Phe Asp Ile Arg Gly Val Leu Asp Arg Gly Pro Ser
100 105 110
Phe Lys Pro Tyr Ser Gly Thr Ala Tyr Asn Ser Leu Ala Pro Lys Gly
115 120 125
Ala Pro Asn Ser Val Glu Trp Pro Asp Asn Thr Lys Thr Lys Val Arg
130 135 140
Ala Gln Ala Pro Phe Val Ser Asp Glu Ile Thr Lys Asp Gly Ile Lys
145 150 155 160
Val Gly Thr Asp Thr Ala Thr Thr Gln Gln Ser Ile Tyr Ala Asp Lys
165 170 175
Thr Phe Gln Pro Glu Pro Gln Val Gly Glu Thr Gln Trp Asn Ser Asp
180 185 190
Val Gly Thr Asn Asp Lys Val Ala Gly Arg Val Leu Lys Lys Asp Thr
195 200 205
Lys Met Lys Pro Cys Tyr Gly Ser Phe Ala Arg Pro Thr Asn Glu Lys
210 215 220
Gly Gly Gln Ala Lys Phe Lys Pro Val Asn Glu Gly Glu Gln Pro Lys
225 230 235 240
Asp Leu Asp Ile Asp Met Gln Phe Phe Ala Thr Thr Ala Ala Asn Thr
245 250 255
Thr Pro Lys Ala Val Leu Tyr Thr Glu Asn Val Asn Leu Glu Thr Pro
260 265 270
Asp Thr His Val Val Tyr Lys Pro Thr Val Thr Glu Gly Thr Thr Ser
275 280 285
Ala Glu Ala Leu Leu Ala Gln Gln Ser Met Pro Asn Arg Pro Asn Tyr
290 295 300
Ile Gly Phe Arg Asp Asn Phe Val Gly Leu Met Tyr Tyr Asn Ser Thr
305 310 315 320
Gly Asn Met Gly Val Leu Ala Gly Gln Ala Ser Gln Leu Asn Ala Val
325 330 335
Val Asp Leu Gln Asp Arg Asn Thr Glu Leu Ser Tyr Gln Leu Leu Leu
340 345 350
Asp Ser Leu Gly Asp Arg Thr Arg Tyr Phe Ser Met Trp Asn Ser Ala
355 360 365
Val Asp Ser Tyr Asp Pro Asp Val Arg Ile Ile Glu Asn His Gly Val
370 375 380
Glu Asp Glu Leu Pro Asn Tyr Cys Phe Pro Leu Gly Gly Met Ala Val
385 390 395 400
Thr Asp Thr Tyr Ser Pro Ile Lys Ser Asn Asn Gly Ser Gly Trp Gln
405 410 415
Val Asp Asn Asp Thr Phe Ala Asp Arg Gly Val Glu Ile Gly Ser Gly
420 425 430
Asn Met Phe Ala Met Glu Ile Asn Leu Gln Ala Asn Leu Trp Lys Ser
435 440 445
Phe Leu Tyr Ser Asn Val Ala Leu Tyr Leu Pro Asp Ser Tyr Lys Tyr
450 455 460
Thr Pro Ala Asn Val Lys Leu Pro Ala Asn Thr Asn Thr Tyr Glu Tyr
465 470 475 480
Met Asn Gly Arg Val Val Ala Pro Ser Leu Val Asp Ala Tyr Ile Asn
485 490 495
Ile Gly Ala Arg Trp Ser Leu Asp Pro Met Asp Asn Val Asn Pro Phe
500 505 510
Asn His His Arg Asn Ala Gly Leu Arg Tyr Arg Ser Met Leu Leu Gly
515 520 525
Asn Gly Arg Tyr Val Pro Phe His Ile Gln Val Pro Gln Lys Phe Phe
530 535 540
Ala Ile Lys Asn Leu Leu Leu Leu Pro Gly Ser Tyr Thr Tyr Glu Trp
545 550 555 560
Asn Phe Arg Lys Asp Val Asn Met Ile Leu Gln Ser Ser Leu Gly Asn
565 570 575
Asp Leu Arg Val Asp Gly Ala Ser Val Arg Phe Asp Ser Val Asn Leu
580 585 590
Tyr Ala Thr Phe Phe Pro Met Ala His Asn Thr Ala Ser Thr Leu Glu
595 600 605
Ala Met Leu Arg Asn Asp Thr Asn Asp Gln Ser Phe Asn Asp Tyr Leu
610 615 620
Ser Ala Ala Asn Met Leu Tyr Pro Ile Pro Ala Lys Ala Thr Asn Val
625 630 635 640
Pro Ile Ser Ile Pro Ser Arg Asn Trp Ala Ala Phe Arg Gly Trp Ser
645 650 655
Phe Thr Arg Leu Lys Thr Lys Glu Thr Pro Ser Leu Gly Ser Gly Phe
660 665 670
Asp Pro Tyr Phe Val Tyr Ser Gly Ser Ile Pro Tyr Leu Asp Gly Thr
675 680 685
Phe Tyr Leu Asn His Thr Phe Lys Lys Val Ser Ile Met Phe Asp Ser
690 695 700
Ser Val Ser Trp Pro Gly Asn Asp Arg Leu Leu Thr Pro Asn Glu Phe
705 710 715 720
Glu Ile Lys Arg Ser Val Asp Gly Glu Gly Tyr Asn Val Ala Gln Cys
725 730 735
Asn Met Thr Lys Asp Trp Phe Leu Val Gln Met Leu Ser His Tyr Asn
740 745 750
Ile Gly Tyr Gln Gly Phe His Val Pro Glu Gly Tyr Lys Asp Arg Met
755 760 765
Tyr Ser Phe Phe Arg Asn Phe Gln Pro Met Ser Arg Gln Val Val Asp
770 775 780
Glu Ile Asn Tyr Lys Asp Tyr Lys Ala Val Thr Leu Pro Phe Gln His
785 790 795 800
Asn Asn Ser Gly Phe Thr Gly Tyr Leu Ala Pro Thr Met Arg Gln Gly
805 810 815
Gln Pro Tyr Pro Ala Asn Phe Pro Tyr Pro Leu Ile Gly Gln Thr Ala
820 825 830
Val Pro Ser Val Thr Gln Lys Lys Phe Leu Cys Asp Arg Val Met Trp
835 840 845
Arg Ile Pro Phe Ser Ser Asn Phe Met Ser Met Gly Ala Leu Thr Asp
850 855 860
Leu Gly Gln Asn Met Leu Tyr Ala Asn Ser Ala His Ala Leu Asp Met
865 870 875 880
Thr Phe Glu Val Asp Pro Met Asp Glu Pro Thr Leu Leu Tyr Leu Leu
885 890 895
Phe Glu Val Phe Asp Val Val Arg Val His Gln Pro His Arg Gly Val
900 905 910
Ile Glu Ala Val Tyr Leu Arg Thr Pro Phe Ser Ala Gly Asn Ala Thr
915 920 925
Thr
<210> 29
<211> 8806
<212> DNA
<213> 人工序列
<220>
<223> pAdApt26.ApoA1.RSVF-2A-GLuc
<400> 29
catcatcaat aatatacccc acaaagtaaa caaaagttaa tatgcaaatg agcttttgaa 60
ttttaacggt tttggggcgg agccaacgct gattggacga gaaacggtga tgcaaatgac 120
gtcacgacgc acggctaacg gtcgccgcgg aggcgtggcc tagcccggaa gcaagtcgcg 180
gggctgatga cgtataaaaa agcggacttt agacccggaa acggccgatt ttcccgcggc 240
cacgcccgga tatgaggtaa ttctgggcgg atgcaagtga aattaggtca ttttggcgcg 300
aaaactgaat gaggaagtga aaagcgaaaa ataccggtcc ctcccagggc ggaatattta 360
ccgagggccg agagactttg accgattacg tgggggtttc gattgcggtg tttttttcgc 420
gaatttccgc gtccgtgtca aagtccggtg tttatgtcac agatcagctg acctaggtgg 480
tcaatattgg ccattagcca tattattcat tggttatata gcataaatca atattggcta 540
ttggccattg catacgttgt atccatatca taatatgtac atttatattg gctcatgtcc 600
aacattaccg ccatgttgac attgattatt gactagttat taatagtaat caattacggg 660
gtcattagtt catagcccat atatggagtt ccgcgttaca taacttacgg taaatggccc 720
gcctggctga ccgcccaacg acccccgccc attgacgtca ataatgacgt atgttcccat 780
agtaacgcca atagggactt tccattgacg tcaatgggtg gagtatttac ggtaaactgc 840
ccacttggca gtacatcaag tgtatcatat gccaagtacg ccccctattg acgtcaatga 900
cggtaaatgg cccgcctggc attatgccca gtacatgacc ttatgggact ttcctacttg 960
gcagtacatc tacgtattag tcatcgctat taccatggtg atgcggtttt ggcagtacat 1020
caatgggcgt ggatagcggt ttgactcacg gggatttcca agtctccacc ccattgacgt 1080
caatgggagt ttgttttggc accaaaatca acgggacttt ccaaaatgtc gtaacaactc 1140
cgccccattg acgcaaatgg gcggtaggcg tgtacggtgg gaggtctata taagcagagc 1200
tcgtttagtg aaccgtcaga tcgcctggag acgccatcca cgctgttttg acctccatag 1260
aagacaccgg gaccgatcca gcctccgcgg ttggccgtgc tcttcctgac gggtaggtgt 1320
cccctaacct agggagccaa ccatcggggg gccttctccc taaatccccg tggcccaccc 1380
tcctgggcag aggcagcagg tttctcactg gccccctctc ccccacctcc aagcttggcc 1440
tttcggctca gatctcagcc cacagctggc ctgatctggg tctcccctcc caccctcagg 1500
gagccaggct cggcatttcg tcgacatgga actgctgatc ctgaaggcca acgccatcac 1560
caccatcctg accgccgtga ccttctgctt cgccagcggc cagaacatca ccgaggaatt 1620
ctaccagagc acctgtagcg ccgtgtccaa gggctacctg agcgccctgc ggaccggctg 1680
gtacaccagc gtgatcacca tcgagctgag caacatcaaa aagaacaagt gcaacggcac 1740
cgacgccaaa atcaagctga tcaagcagga actggacaag tacaagaacg ccgtgaccga 1800
gctgcagctg ctgatgcaga gcacccccgc caccaacaac cgggccagac gggagctgcc 1860
ccggttcatg aactacaccc tgaacaacgc caaaaagacc aacgtgaccc tgagcaagaa 1920
gcggaagcgg cggttcctgg gcttcctgct gggcgtgggc agcgccattg ctagcggagt 1980
ggctgtgtct aaggtgctgc acctggaagg cgaagtgaac aagatcaagt ccgccctgct 2040
gagcaccaac aaggccgtgg tgtccctgag caacggcgtg tccgtgctga ccagcaaggt 2100
gctggatctg aagaactaca tcgacaagca gctgctgccc atcgtgaaca agcagagctg 2160
cagcatcagc aacatcgaga cagtgatcga gttccagcag aagaacaacc ggctgctgga 2220
aatcacccgc gagttcagcg tgaacgccgg cgtgaccacc cccgtgtcca cctacatgct 2280
gaccaacagc gagctgctga gcctgatcaa cgacatgccc atcaccaacg accagaaaaa 2340
gctgatgagc aacaacgtgc agatcgtgcg gcagcagagc tactccatca tgtccatcat 2400
caaagaagag gtgctggcct acgtggtgca gctgcccctg tacggcgtga tcgacacccc 2460
ctgctggaag ctgcacacca gccccctgtg caccaccaac accaaagagg gcagcaacat 2520
ctgcctgacc cggaccgacc ggggctggta ctgcgataat gccggcagcg tgtcattctt 2580
tccacaagcc gagacatgca aggtgcagag caaccgggtg ttctgcgaca ccatgaacag 2640
cctgaccctg cccagcgagg tgaacctgtg caacgtggac atcttcaacc ctaagtacga 2700
ctgcaagatc atgacctcca agaccgacgt gtccagctcc gtgatcacct ccctgggcgc 2760
catcgtgtcc tgctacggca agaccaagtg caccgccagc aacaagaacc ggggcatcat 2820
caagaccttc agcaacggct gcgactacgt gtccaacaag ggcgtggaca ccgtgtccgt 2880
gggcaacacc ctgtactacg tgaacaaaca ggaaggcaag agcctgtacg tgaagggcga 2940
gcccatcatc aacttctacg accccctggt gttccccagc gacgagttcg acgccagcat 3000
cagccaggtc aacgagaaga tcaaccagag cctggccttc atcagaaaga gcgacgagct 3060
gctgcacaat gtgaatgccg tgaagtccac caccaatatc atgatcacca caatcatcat 3120
cgtgatcatc gtcatcctgc tgtccctgat cgccgtgggc ctgctgctgt actgcaaggc 3180
ccggtccacc cctgtgaccc tgtccaagga ccagctgagc ggcatcaaca atatcgcctt 3240
ctccaacgga cgcgtgaccg agctgcttta ccggatgaag cgggctgaga catattgccc 3300
gagacccctg ttggcaatcc atcctactga ggctcgccac aaacagaaaa tcgtggcccc 3360
cgtcaaacag acactcaatt ttgacttgtt gaaacttgca ggagatgttg agtcaaaccc 3420
cgggcctatg ggcgtcaagg tcctgttcgc tctgatttgt atcgctgtcg ctgaagctaa 3480
gccaaccgag aataatgaag actttaatat cgtggccgtg gcttctaact tcgctaccac 3540
agacctggat gcagacaggg gaaagctgcc aggcaagaaa ctgcccctgg aggtcctgaa 3600
ggagatggaa gcaaatgccc ggaaagccgg gtgcacaaga ggatgcctga tttgtctgag 3660
ccacatcaag tgcactccta agatgaagaa gttcatcccc ggccggtgcc atacctacga 3720
gggcgataag gaatccgccc agggaggaat cggagaggct atcgtggata ttcccgaaat 3780
ccctggcttc aaagacctgg agcccatgga acagtttatt gcacaggtgg atctgtgcgt 3840
cgactgtact accggatgcc tgaagggact ggcaaacgtc cagtgtagcg acctgctgaa 3900
gaaatggctg cctcagcgat gtgctacatt tgccagcaag attcagggcc aggtggacaa 3960
gattaaggga gcaggaggcg actgataatt ctagacgaga tccgaacttg tttattgcag 4020
cttataatgg ttacaaataa agcaatagca tcacaaattt cacaaataaa gcattttttt 4080
cactgcattc tagttgtggt ttgtccaaac tcatcaatgt atcttatcat gtctagatcc 4140
aggtaggttt gagtagtggg cgtggctaag gtgactataa aggcgggtgt cttacgaggg 4200
tctttttgct tttctgcaga catcatgaac gggactggcg gggccttcga aggggggctt 4260
tttagccctt atttgacaac ccgcctgccg ggatgggccg gagttcgtca gaatgtgatg 4320
ggatcgacgg tggatgggcg cccagtgctt ccagcaaatt cctcgaccat gacctacgcg 4380
accgtgggga actcgtcgct cgacagcacc gccgcagccg cggcagccgc agccgccatg 4440
acagcgacga gactggcctc gagctacatg cccagcagcg gtagtagccc ctctgtgccc 4500
agttccatca tcgccgagga gaaactgctg gccctgctgg ccgagctgga agccctgagc 4560
cgccagctgg ccgccctgac ccagcaggtg tccgagctcc gcgaacagca gcagcagcaa 4620
aataaatgat tcaataaaca cagattctga ttcaaacagc aaagcatctt tattatttat 4680
tttttcgcgc gcggtaggcc ctggtccacc tctcccgatc attgagagtg cggtggattt 4740
tttccaggac ccggtagagg tgggattgga tgttgaggta catgggcatg agcccgtccc 4800
gtgggtggag gtagcaccac tgcatggcct cgtgctctgg ggtcgtgttg tagatgatcc 4860
agtcatagca ggggcgctgg gcgtggtgct ggatgatgtc cttgaggagg agactgatgg 4920
ccacggggag ccccttggtg taggtgttgg caaaacggtt gagctgggag ggatgcatgc 4980
ggggggagat gatgtgcagt ttggcctgga tcttgaggtt ggcgatgttg ccacccagat 5040
cccgccgggg gttcatgttg tgcaggacca ccagaacggt gtagcccgtg cacttgggga 5100
acttgtcatg caacttggaa gggaatgcgt ggaagaattt ggagacgccc ttgtgcccgc 5160
ccaggttttc catgcactca tccatgatga tggcaatggg cccgtgggct gcggctttgg 5220
caaagacgtt tctggggtca gagacatcgt aattatgctc ctgggtgaga tcatcataag 5280
acattttaat gaatttgggg cggagggtgc cagattgggg gacgatggtt ccctcgggcc 5340
ccggggcgaa gttcccctcg cagatctgca tctcccaggc tttcatctcg gaggggggga 5400
tcatgtccac ctgcggggcg atgaaaaaaa cggtttccgg ggcgggggtg atgagctgcg 5460
aggagagcag gtttctcaac agctgggact tgccgcaccc ggtcgggccg tagatgaccc 5520
cgatgacggg ttgcaggtgg tagttcaagg acatgcagct gccgtcgtcc cggaggaggg 5580
gggccacctc gttgagcttg tctctgactt ggaggttttc ccggacgagc tcgccgagga 5640
ggcggtcccc gcccagcgag agaagctctt gcagggaagc aaagtttttc aggggcttga 5700
gcccgtcggc catgggcatc ttggcgaggg tctgcgagag gagctccagg cggtcccaga 5760
gctcggtgac gtgctctacg gcatctcgat ccagcagact tcctcgtttc gggggttggg 5820
acgactgcga ctgtagggca cgagacgatg ggcgtccagc gcggccagcg tcatgtcctt 5880
ccagggtctc agggtccgcg tgagggtggt ctccgtcacg gtgaaggggt gggccgcggg 5940
ctgggcgctt gcaagggtgc gcttgagact catcctgctg gtgctgaaac gggcacggtc 6000
ttcgccctgc gcgtcggcga gatagcagtt gaccatgagc tcgtagttga gggcctcggc 6060
ggcgtggccc ttggcgcgga gcttgccctt ggaagagcgc ccgcaggcgg gacagaggag 6120
ggattgcagg gcgtagagct tgggcgcgag aaagacggac tcgggggcga aggcgtccgc 6180
tccgcagtgg gcgcagacgg tctcgcactc gactagccag gtgagctcgg gctgctcggg 6240
gtcaaaaacc agttttcccc cgttcttttt gatgcgcttc ttacctcgcg tctccatgag 6300
tctgtgtccg cgctcggtga caaacaggct gtctgtgtcc ccgtagacgg acttgatggg 6360
cctgtcctgc aggggcgtcc cgcggtcctc ctcgtagaga aactcagacc actctgagac 6420
gaaggcgcgc gtccacgcca agacaaagga ggccacgtgc gaggggtagc ggtcgttgtc 6480
caccaggggg tccacctttt ccacggtatg caggcacatg tccccctcct ccgcatccaa 6540
gaaggtgatt ggcttgtagg tgtaggccac gtgacctggg gttcccgacg ggggggtata 6600
aaagggggcg ggtctgtgct cgtcctcact ctcttccgcg tcgctgtcca cgagcgccag 6660
ctgttggggt aggtattccc tctcaagatt aattaattcg aacccataat acccataata 6720
gctgtttgcc atcgacgcga ggctggatgg ccttccccat tatgattctt ctcgcttccg 6780
gcggcatcgg gatgcccgcg ttgcaggcca tgctgtccag gcaggtagat gacgaccatc 6840
agggacagct tcaaggatcg ctcgcggctc ttaccagccc agcaaaaggc caggaaccgt 6900
aaaaaggccg cgttgctggc gtttttccat aggctccgcc cccctgacga gcatcacaaa 6960
aatcgacgct caagtcagag gtggcgaaac ccgacaggac tataaagata ccaggcgttt 7020
ccccctggaa gctccctcgt gcgctctcct gttccgaccc tgccgcttac cggatacctg 7080
tccgcctttc tcccttcggg aagcgtggcg ctttctcata gctcacgctg taggtatctc 7140
agttcggtgt aggtcgttcg ctccaagctg ggctgtgtgc acgaaccccc cgttcagccc 7200
gaccgctgcg ccttatccgg taactatcgt cttgagtcca acccggtaag acacgactta 7260
tcgccactgg cagcagccac tggtaacagg attagcagag cgaggtatgt aggcggtgct 7320
acagagttct tgaagtggtg gcctaactac ggctacacta gaaggacagt atttggtatc 7380
tgcgctctgc tgaagccagt taccttcgga aaaagagttg gtagctcttg atccggcaaa 7440
caaaccaccg ctggtagcgg tggttttttt gtttgcaagc agcagattac gcgcagaaaa 7500
aaaggatctc aagaagatcc tttgatcttt tctacggggt ctgacgctca gtggaacgaa 7560
aactcacgtt aagggatttt ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt 7620
ttaaattaaa aatgaagttt taaatcaatc taaagtatat atgagtaaac ttggtctgac 7680
agttaccaat gcttaatcag tgaggcacct atctcagcga tctgtctatt tcgttcatcc 7740
atagttgcct gactccccgt cgtgtagata actacgatac gggagggctt accatctggc 7800
cccagtgctg caatgatacc gcgagaccca cgctcaccgg ctccagattt atcagcaata 7860
aaccagccag ccggaagggc cgagcgcaga agtggtcctg caactttatc cgcctccatc 7920
cagtctatta attgttgccg ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc 7980
aacgttgttg ccattgctgc aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca 8040
ttcagctccg gttcccaacg atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa 8100
gcggttagct ccttcggtcc tccgatcgtt gtcagaagta agttggccgc agtgttatca 8160
ctcatggtta tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt 8220
tctgtgactg gtgagtactc aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt 8280
tgctcttgcc cggcgtcaac acgggataat accgcgccac atagcagaac tttaaaagtg 8340
ctcatcattg gaaaacgttc ttcggggcga aaactctcaa ggatcttacc gctgttgaga 8400
tccagttcga tgtaacccac tcgtgcaccc aactgatctt cagcatcttt tactttcacc 8460
agcgtttctg ggtgagcaaa aacaggaagg caaaatgccg caaaaaaggg aataagggcg 8520
acacggaaat gttgaatact catactcttc ctttttcaat attattgaag catttatcag 8580
ggttattgtc tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg 8640
gttccgcgca catttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg 8700
acattaacct ataaaaatag gcgtatcacg aggccctttc gtcttcaaga attggtcgat 8760
ggcaaacagc tattatgggt attatgggtt cgaattaatt aatcga 8806

Claims (13)

1.一种腺病毒载体,该腺病毒载体包含编码六邻体多肽的核酸序列,该六邻体多肽由选自SEQ ID NO:3或SEQ ID NO:4的氨基酸序列组成。
2.如权利要求1所述的腺病毒载体,其中该腺病毒载体进一步包含E1缺失。
3.如权利要求1-2中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含E3缺失。
4.如权利要求1-2中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含人腺病毒-5E4 orf6。
5.如权利要求1-2中任一项所述的腺病毒载体,其中该腺病毒载体包含选自SEQ IDNO:5或SEQ ID NO:6的核酸序列。
6.如权利要求1-2中任一项所述的腺病毒载体,其中该腺病毒载体进一步包含至少一个转基因。
7.如权利要求6所述的腺病毒载体,其中该转基因位于E1缺失处、E3缺失处、和/或右反向末端重复序列附近。
8.如权利要求1-2中任一项所述的腺病毒载体,其中该腺病毒载体包含来自人腺病毒-26的一种或多种核酸序列。
9.一种重组细胞,该重组细胞包含如权利要求1-8中任一项所述的腺病毒载体。
10.一种生产腺病毒载体的方法,该方法包括:
(a)使如权利要求9所述的重组细胞在用于生产该腺病毒载体的条件下生长;以及
(b)从该重组细胞中分离该腺病毒载体。
11.一种免疫原性组合物,该免疫原性组合物包含如权利要求1-8中任一项所述的腺病毒载体、以及药学上可接受的载剂。
12.如权利要求11所述的免疫原性组合物在制备用于在有需要的受试者中诱导免疫应答的药物中的用途。
13.一种生产免疫原性组合物的方法,该方法包括将如权利要求1-8中任一项所述的腺病毒载体与药学上可接受的载剂组合。
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