CN110771894A - 一种鹿茸口服液及制备方法 - Google Patents
一种鹿茸口服液及制备方法 Download PDFInfo
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- CN110771894A CN110771894A CN201911284246.5A CN201911284246A CN110771894A CN 110771894 A CN110771894 A CN 110771894A CN 201911284246 A CN201911284246 A CN 201911284246A CN 110771894 A CN110771894 A CN 110771894A
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Abstract
本发明公开了一种鹿茸口服液及制备方法，所述的鹿茸口服液由下述重量份配比的原料制成：枸杞子200‑300份、红景天100‑150份、西洋参60‑120份、马鹿茸粉20‑40份、蜂蜜60‑90份、山梨酸钾0.8‑1.2份、纯净水适量。其制备方法包括如下步骤：将西洋参粉碎与马鹿茸粉混合用乙醇提取，制得醇溶提取液和参茸药渣；将红景天、枸杞子和参茸药渣混合用水提取浓缩，制得水溶浓缩液；将醇溶提取液和水溶浓缩液混合为合并提取液，合并提取液经过沉淀，取上清液离心制得离心上清液和离心药渣；在离心上清液中按比例加入蜂蜜、山梨酸钾和适量的纯净水，再经过滤、灌装和灭菌，制得鹿茸口服液成品。它具有增强免疫力、缓解体力疲劳的功效；产品质量稳定，无沉淀，口感好，服用后吸收率高。
Description
技术领域
本发明属于保健食品及其制造技术领域，尤其涉及一种鹿茸口服液及制备方法。
背景技术
经临床研究和动物实验证实，马鹿茸及其制品有提高免疫功能抗衰老、抗疲劳、改善性功能，保护心脏等良好疗效，是一种保健、预防、治疗作用俱佳的生物制品。
自古以来，我国习惯用白酒浸制鹿茸片，但是酒中会出现大量沉淀物，人饮用后不能充分吸收。在配制鹿茸酒时，经常加入一些具有保健功能的要用植物，一方面，配伍不合理，经常出现配伍禁忌或者不全理用药的情况，另一方面，药材和酒水含水量很高，浸泡时间没有严格的规定，不进行灭菌处理，在浸泡的过程中会滋生致病菌，对健康有潜在的危害。
发明内容
本发明的目的在于提供一种鹿茸口服液及制备方法，它发挥了各有效组分的协同增效作用，提高了有效组分的抗氧化活性，具有增强免疫力、缓解体力疲劳的功效；它的制备方法充分提取了各原料的有效成分，口服液产品质量稳定，无沉淀，口感好，服用后吸收率高。
本发明的目的是通过如下技术方案来实现的，一种鹿茸口服液，其特征在于，由下述重量份配比的原料制成：枸杞子200-300份、红景天100-150份、西洋参60-120份、马鹿茸粉20-40份、蜂蜜60-90份、山梨酸钾0.8-1.2份、纯净水适量。
作为本发明鹿茸口服液的优化方案，由下述重量份配比的原料制成：枸杞子220-280份、红景天120-130份、西洋参80-100份、马鹿茸粉25-35份、蜂蜜70-80份、山梨酸钾0.9-1.1份、纯净水适量。
作为本发明鹿茸口服液的最佳方案：由下述重量份配比的原料制成：枸杞子250份、红景天125份、西洋参90份、马鹿茸粉30份、蜂蜜75份、山梨酸钾1份、纯净水适量。
本发明鹿茸口服液的制造方法包括如下步骤：
1）按比例将西洋参粉碎与马鹿茸粉混合用乙醇提取，回收乙醇制得醇溶提取液和参茸药渣；
2）按比例将红景天、枸杞子和参茸药渣混合用水提取，过滤制得水溶提取液和药物残渣；水溶提取液经过浓缩制得水溶浓缩液；
3）将醇溶提取液和水溶浓缩液混合为合并提取液，合并提取液经过沉淀，取上清液离心制得离心上清液和离心药渣；
4）在离心上清液中按比例加入蜂蜜、山梨酸钾和适量的纯净水，再经过滤、灌装和灭菌，制得鹿茸口服液成品。
优选的，步骤1）中，使用60%乙醇进行两次浸提，每次加入西洋参粉和马鹿茸粉重量7～9倍量60%乙醇，每次浸提1.5-2.5小时。
优选的，步骤2）中，首先在红景天、枸杞子和参茸药渣药物混合物中加入药物混合物重量8～12倍量的水，常温浸泡0.5-1.5小时；然后加热至75-85℃浸提1.5-2.5小时，过滤收集一次浸提液和混合药渣；再然后在混合药渣中加入混合药渣重量8～12倍量的水，加热至75-85℃浸提1.5-2.5小时，过滤收集二次浸提液和药物废渣，将一次浸提液和二次浸提液合并为水溶提取液。
优选的，步骤2）中，将水溶提取液浓缩至密度为1.01-1.10 g/cm³；更优选的，将水溶提取液浓缩至密度为1.05g/cm³。
优选的，步骤3）中，合并提取液在3-7℃的温度下，静置冷藏沉淀20-30小时，取上清液进行100目离心过滤制得离心上清液和离心药渣。
与现有技术相比本发明的有益效果为：
（1）本发明的配方中含有枸杞子，枸杞子具有滋补肝肾、益精明目之功效。用于虚劳精亏、腰膝酸软、眩昏耳鸣、内热消渴等。枸杞子富含多糖、类胡萝卜素等营养成分，还含有核黄素、维生素C、维生素B1、尼克酸、牛磺酸及铜、铁、锌、锰、镁、硒等多种微量元素。枸杞多糖在免疫方面具有重要的作用。
（2）本发明的配方中含有红景天，红景天含有黄酮类、皂甙类、氨基酸类、酚类、香豆素类、萜类、矿物质、酶类、挥发油类以及其它常见的大分子物质，如多糖类、果胶、脂类、蛋白质和蜡等。具有抗疲劳、抗氧化、抗衰老、抗缺氧、抗肿瘤、保护心血管、改善睡眠及免疫调节等。
（3）本发明的配方中含有西洋参，西洋参具有滋补强壮、养血生津、宁神益智等功能。
（4）本发明的配方中含有马鹿茸，马鹿茸具有壮肾阳、益精血、强筋骨、调冲任、托疮毒等作用，用于阳痿滑精、宫冷不孕、赢瘦、神疲、畏寒、眩晕耳聋、腰背冷痛、筋骨痿软、崩漏带下等。
（5）本发明的主要原料为枸杞子、红景天、西洋参、马鹿茸粉，配伍合理，皂甙类物质及多糖类物质含量丰富，协同增效作用显著，具有增强免疫力、缓解体力疲劳的保健功能。
（6）本发明的制备方法根据不同原料的特性，采取了不同的提取方法，其中，西洋参粉和马鹿茸粉采用乙醇提取，经过乙醇提取之后的参茸药渣与枸杞子、红景天混合用水提取，能最大限度地将药物原料中的有效成分提取出来，服用后吸收率高，保健效果好。
（7）本发明的制备方法制备的提取液经过多个环节的过滤、沉淀、澄清和浓缩，添加了蜂蜜、山梨酸钾和适量的纯净水，口服液产品质量稳定，无沉淀，食用安全，口感好，适合免疫力低下者、易疲劳者人群服用。
具体实施方式
下面结合实施例进一步阐述本发明内容。
实施例1：一种鹿茸口服液，它的制备方法包括如下步骤：
1）将90kg西洋参粉碎与30kg马鹿茸粉混合，使用60%乙醇进行两次浸提，每次加入60%乙醇960L，每次浸提2小时，回收乙醇制得醇溶提取液和参茸药渣；
2）例将125kg红景天、250kg枸杞子和参茸药渣混合，加入4950L水，常温浸泡1小时；然后加热至80℃浸提2小时，过滤收集一次浸提液和混合药渣；再然后在混合药渣中加入4950L水，加热至80℃浸提2小时，过滤收集二次浸提液和药物废渣，将一次浸提液和二次浸提液合并为水溶提取液，将水溶提取液浓缩至密度为1.05 kg/cm³的水溶浓缩液；
3）将醇溶提取液和水溶浓缩液混合为合并提取液，将合并提取液在5℃的温度下，静置冷藏沉淀24小时，取上清液进行100目离心过滤制得离心上清液和离心药渣；
4）在离心上清液中加入75kg蜂蜜和1kg山梨酸钾，加入纯净水定容至1000L，经过滤、灌装和灭菌，制得鹿茸口服液成品。
实施例:2：一种鹿茸口服液，它的制备方法包括如下步骤：
1）将80kg西洋参粉碎与25kg马鹿茸粉混合，使用60%乙醇进行两次浸提，每次加入60%乙醇840L，每次浸提2.2小时，回收乙醇制得醇溶提取液和参茸药渣；
2）例将150kg红景天、200kg枸杞子和参茸药渣混合，加入3960L水，常温浸泡1.5小时；然后加热至75℃浸提2.5小时，过滤收集一次浸提液和混合药渣；再然后在混合药渣中加入3960L水，加热至85℃浸提2.5小时，过滤收集二次浸提液和药物废渣，将一次浸提液和二次浸提液合并为水溶提取液，将水溶提取液浓缩至密度为1.05 kg/cm³的水溶浓缩液；
3）将醇溶提取液和水溶浓缩液混合为合并提取液，将合并提取液在4℃的温度下，静置冷藏沉淀30小时，取上清液进行100目离心过滤制得离心上清液和离心药渣；
4）在离心上清液中加入60kg蜂蜜和1.2kg山梨酸钾，加入纯净水定容至1000L，经过滤、灌装和灭菌，制得鹿茸口服液成品。
实施例3：一种鹿茸口服液，它的制备方法包括如下步骤：
1）将100kg西洋参粉碎与35kg马鹿茸粉混合，使用60%乙醇进行两次浸提，每次加入60%乙醇1000L，每次浸提1.8小时，回收乙醇制得醇溶提取液和参茸药渣；
2）例将100kg红景天、300kg枸杞子和参茸药渣混合，加入5940L水，常温浸泡0.5小时；然后加热至75℃浸提1.5小时，过滤收集一次浸提液和混合药渣；再然后在混合药渣中加入5940L水，加热至85℃浸提1.5小时，过滤收集二次浸提液和药物废渣，将一次浸提液和二次浸提液合并为水溶提取液，将水溶提取液浓缩至密度为1.10 kg/cm³的水溶浓缩液；
3）将醇溶提取液和水溶浓缩液混合为合并提取液，将合并提取液在5℃的温度下，静置冷藏沉淀20小时，取上清液进行100目离心过滤制得离心上清液和离心药渣；
4）在离心上清液中加入90kg蜂蜜和0.8kg山梨酸钾，加入纯净水定容至1000L，经过滤、灌装和灭菌，制得鹿茸口服液成品。
Claims (8)
1.一种鹿茸口服液，其特征在于：由下述重量份配比的原料制成：枸杞子200-300份、红景天100-150份、西洋参60-120份、马鹿茸粉20-40份、蜂蜜60-90份、山梨酸钾0.8-1.2份、纯净水适量。
2.根据权利要求1所述的鹿茸口服液，其特征在于：由下述重量份配比的原料制成：枸杞子220-280份、红景天120-130份、西洋参80-100份、马鹿茸粉25-35份、蜂蜜70-80份、山梨酸钾0.9-1.1份、纯净水适量。
3.根据权利要求2所述的鹿茸口服液，其特征在于：由下述重量份配比的原料制成：枸杞子250份、红景天125份、西洋参90份、马鹿茸粉30份、蜂蜜75份、山梨酸钾1份、纯净水适量。
4.权利要求1至3任意一项所述鹿茸口服液的制备方法，它包括如下步骤：
1）按比例将西洋参粉碎与马鹿茸粉混合用乙醇提取，回收乙醇制得醇溶提取液和参茸药渣；
2）按比例将红景天、枸杞子和参茸药渣混合用水提取，过滤制得水溶提取液和药物残渣；水溶提取液经过浓缩制得水溶浓缩液；
3）将醇溶提取液和水溶浓缩液混合为合并提取液，合并提取液经过沉淀，取上清液离心制得离心上清液和离心药渣；
4）在离心上清液中按比例加入蜂蜜、山梨酸钾和适量的纯净水，再经过滤、灌装和灭菌，制得鹿茸口服液成品。
5.根据权利要求4所述鹿茸口服液的制备方法，其特征在于：步骤1）中，使用60%乙醇进行两次浸提，每次加入西洋参粉和马鹿茸粉重量7～9倍量60%乙醇，每次浸提1.5-2.5小时。
6.根据权利要求5所述鹿茸口服液的制备方法，其特征在于：步骤2）中，首先在红景天、枸杞子和参茸药渣药物混合物中加入药物混合物重量8～12倍量的水，常温浸泡0.5-1.5小时；然后加热至75-85℃浸提1.5-2.5小时，过滤收集一次浸提液和混合药渣；再然后在混合药渣中加入混合药渣重量8～12倍量的水，加热至75-85℃浸提1.5-2.5小时，过滤收集二次浸提液和药物废渣，将一次浸提液和二次浸提液合并为水溶提取液。
7.根据权利要求6所述鹿茸口服液的制备方法，其特征在于：步骤2）中，将水溶提取液浓缩至密度为1.01-1.10 g/cm³的水溶浓缩液。
8.根据权利要求7所述鹿茸口服液的制备方法，其特征在于：步骤3）中，合并提取液在3-7℃的温度下，静置冷藏沉淀20-30小时，取上清液进行100目离心过滤制得离心上清液和离心药渣。
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