CN110769873B - 具有可变的柱塞力的自动注射器 - Google Patents
具有可变的柱塞力的自动注射器 Download PDFInfo
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- CN110769873B CN110769873B CN201880033657.4A CN201880033657A CN110769873B CN 110769873 B CN110769873 B CN 110769873B CN 201880033657 A CN201880033657 A CN 201880033657A CN 110769873 B CN110769873 B CN 110769873B
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- China
- Prior art keywords
- plunger rod
- rod position
- high resistance
- barrel
- auto
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
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- A61M5/484—Regulating injection pressure
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- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/488—Limiting injection pressure
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- A—HUMAN NECESSITIES
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- A61M5/178—Syringes
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- A61M2005/2006—Having specific accessories
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- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
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- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
- A61M2205/103—General characteristics of the apparatus with powered movement mechanisms rotating
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/215—Tilt detection, e.g. for warning or shut-off
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- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Fuel-Injection Apparatus (AREA)
- Valve Device For Special Equipments (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211226408.1A CN115591054A (zh) | 2017-05-23 | 2018-05-23 | 自动注射器、系统和用于控制自动注射器的方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17172456.0 | 2017-05-23 | ||
EP17172456 | 2017-05-23 | ||
PCT/EP2018/063460 WO2018215516A1 (en) | 2017-05-23 | 2018-05-23 | Auto injector with variable plunger force |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211226408.1A Division CN115591054A (zh) | 2017-05-23 | 2018-05-23 | 自动注射器、系统和用于控制自动注射器的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110769873A CN110769873A (zh) | 2020-02-07 |
CN110769873B true CN110769873B (zh) | 2022-11-01 |
Family
ID=58778897
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211226408.1A Pending CN115591054A (zh) | 2017-05-23 | 2018-05-23 | 自动注射器、系统和用于控制自动注射器的方法 |
CN201880033657.4A Active CN110769873B (zh) | 2017-05-23 | 2018-05-23 | 具有可变的柱塞力的自动注射器 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211226408.1A Pending CN115591054A (zh) | 2017-05-23 | 2018-05-23 | 自动注射器、系统和用于控制自动注射器的方法 |
Country Status (11)
Country | Link |
---|---|
US (2) | US11684724B2 (ja) |
EP (1) | EP3630232A1 (ja) |
JP (3) | JP7146816B2 (ja) |
KR (2) | KR20230056801A (ja) |
CN (2) | CN115591054A (ja) |
AU (2) | AU2018272907B2 (ja) |
BR (1) | BR112019024511A2 (ja) |
CA (1) | CA3063977A1 (ja) |
MX (1) | MX2019013691A (ja) |
RU (2) | RU2766528C2 (ja) |
WO (1) | WO2018215516A1 (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3791919A1 (en) | 2015-03-10 | 2021-03-17 | Regeneron Pharmaceuticals, Inc. | Aseptic piercing system |
CA3004745A1 (en) | 2015-11-12 | 2017-05-18 | University Of Virginia Patent Foundation | Compositions and methods for vas-occlusive contraception and reversal thereof |
WO2017114906A1 (en) | 2015-12-30 | 2017-07-06 | Ascendis Pharma A/S | Auto injector with cartridge locking system |
US11406760B2 (en) | 2015-12-30 | 2022-08-09 | Ascendis Pharma A/S | Auto injector with charger safety |
NZ742538A (en) | 2015-12-30 | 2023-06-30 | Ascendis Pharma As | Auto injector with adaptable air-shot mechanism |
EP3397321B1 (en) | 2015-12-30 | 2022-10-05 | Ascendis Pharma A/S | Auto injector with temperature control |
US11179524B2 (en) | 2015-12-30 | 2021-11-23 | Ascendis Pharma A/S | Auto injector with detection of used cartridge and associated method |
MX2019012670A (es) | 2017-05-05 | 2020-07-13 | Regeneron Pharma | Autoinyector. |
KR20230056801A (ko) | 2017-05-23 | 2023-04-27 | 아센디스 파마 에이에스 | 가변 플런저 힘을 갖는 자동 인젝터 |
MX2019013977A (es) | 2017-06-29 | 2020-08-03 | Ascendis Pharma As | Inyector automatico con soporte de manejo de reconstitucion. |
EP3880273A4 (en) | 2018-11-13 | 2022-08-24 | Contraline, Inc. | BIOMATERIALS DELIVERY SYSTEMS AND METHODS |
WO2020226842A1 (en) | 2019-05-06 | 2020-11-12 | Battelle Memorial Institute | Autoinjector and methods of injecting fluids |
US11738154B2 (en) * | 2019-09-11 | 2023-08-29 | Altaviz, Llc | Micro-volume injectors with dose guidance and methods for use |
AU2022354110A1 (en) * | 2021-09-30 | 2024-03-07 | Ascendis Pharma A/S | Auto injector with measurement of battery capacity left before re-charging is required |
WO2023079393A1 (en) * | 2021-11-04 | 2023-05-11 | Janssen Research & Development, Llc | Light-based visual cues that assist in medication delivery to a patient |
USD1007676S1 (en) | 2021-11-16 | 2023-12-12 | Regeneron Pharmaceuticals, Inc. | Wearable autoinjector |
WO2024006163A2 (en) * | 2022-06-27 | 2024-01-04 | Contraline, Inc. | Systems and methods for delivering a composition |
CN116899050A (zh) * | 2023-05-10 | 2023-10-20 | 巨翊科技(上海)有限公司 | 一种基于薄膜压力传感器的自动注射的控制方法和系统 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102307605A (zh) * | 2009-02-05 | 2012-01-04 | 赛诺菲-安万特德国有限公司 | 药物递送装置 |
CN102413852A (zh) * | 2009-02-27 | 2012-04-11 | 生命扫描有限公司 | 给药管理系统和方法 |
CN103813820A (zh) * | 2011-11-10 | 2014-05-21 | 松下健康医疗器械株式会社 | 药剂注入装置 |
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RU2766528C2 (ru) | 2022-03-15 |
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JP2020520766A (ja) | 2020-07-16 |
RU2022102956A (ru) | 2022-03-03 |
AU2018272907A1 (en) | 2019-11-07 |
JP2024050904A (ja) | 2024-04-10 |
JP7146816B2 (ja) | 2022-10-04 |
KR20200011954A (ko) | 2020-02-04 |
AU2018272907B2 (en) | 2023-07-13 |
CA3063977A1 (en) | 2018-11-29 |
MX2019013691A (es) | 2020-07-14 |
KR102526705B1 (ko) | 2023-04-27 |
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