CN110643510A - 细胞培养系统及防止交叉污染的细胞培养方法 - Google Patents
细胞培养系统及防止交叉污染的细胞培养方法 Download PDFInfo
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- CN110643510A CN110643510A CN201810666392.3A CN201810666392A CN110643510A CN 110643510 A CN110643510 A CN 110643510A CN 201810666392 A CN201810666392 A CN 201810666392A CN 110643510 A CN110643510 A CN 110643510A
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- 238000004113 cell culture Methods 0.000 title claims abstract description 51
- 238000012864 cross contamination Methods 0.000 title claims abstract description 12
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- 238000000034 method Methods 0.000 claims abstract description 21
- 230000007246 mechanism Effects 0.000 claims abstract description 17
- 230000001954 sterilising effect Effects 0.000 claims abstract description 17
- 230000007613 environmental effect Effects 0.000 claims abstract description 16
- 238000012544 monitoring process Methods 0.000 claims abstract description 13
- 238000012545 processing Methods 0.000 claims abstract description 13
- 238000007599 discharging Methods 0.000 claims abstract description 11
- 238000012546 transfer Methods 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims description 22
- 238000003860 storage Methods 0.000 claims description 15
- 230000008569 process Effects 0.000 claims description 13
- 239000002245 particle Substances 0.000 claims description 12
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 239000010813 municipal solid waste Substances 0.000 claims description 7
- 238000004891 communication Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 206010011409 Cross infection Diseases 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000012832 cell culture technique Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
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- 238000009423 ventilation Methods 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
- 239000002912 waste gas Substances 0.000 description 1
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
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- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
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- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
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CN201810666392.3A CN110643510A (zh) | 2018-06-26 | 2018-06-26 | 细胞培养系统及防止交叉污染的细胞培养方法 |
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CN201810666392.3A CN110643510A (zh) | 2018-06-26 | 2018-06-26 | 细胞培养系统及防止交叉污染的细胞培养方法 |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130189671A1 (en) * | 2010-08-19 | 2013-07-25 | Jan H. Hoh | Cell Culture System and Method of Use Thereof |
CN104498358A (zh) * | 2014-12-18 | 2015-04-08 | 宁波新芝生物科技股份有限公司 | 一种细胞培养一体机 |
CN205515662U (zh) * | 2016-01-30 | 2016-08-31 | 山东新华医疗器械股份有限公司 | Vhp灭菌传递柜 |
WO2017218832A1 (en) * | 2016-06-17 | 2017-12-21 | Sterifre Medical Inc. | Sterilization, disinfection, sanitization, decontamination, and therapeutic devices, systems, and methods |
CN108611272A (zh) * | 2018-05-16 | 2018-10-02 | 余春 | 一种多批次生物制品共线制备的系统及方法 |
CN108611264A (zh) * | 2018-05-10 | 2018-10-02 | 朱丹 | 一种多批次生物制品共线制备的系统及方法 |
-
2018
- 2018-06-26 CN CN201810666392.3A patent/CN110643510A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130189671A1 (en) * | 2010-08-19 | 2013-07-25 | Jan H. Hoh | Cell Culture System and Method of Use Thereof |
CN104498358A (zh) * | 2014-12-18 | 2015-04-08 | 宁波新芝生物科技股份有限公司 | 一种细胞培养一体机 |
CN205515662U (zh) * | 2016-01-30 | 2016-08-31 | 山东新华医疗器械股份有限公司 | Vhp灭菌传递柜 |
WO2017218832A1 (en) * | 2016-06-17 | 2017-12-21 | Sterifre Medical Inc. | Sterilization, disinfection, sanitization, decontamination, and therapeutic devices, systems, and methods |
CN108611264A (zh) * | 2018-05-10 | 2018-10-02 | 朱丹 | 一种多批次生物制品共线制备的系统及方法 |
CN108611272A (zh) * | 2018-05-16 | 2018-10-02 | 余春 | 一种多批次生物制品共线制备的系统及方法 |
Non-Patent Citations (1)
Title |
---|
陈华弟: "无菌隔离器的发展和应用", 《医药工程设计》 * |
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