CN110638718B

CN110638718B - Anti-aging preparation, anti-aging composition, and preparation method and application thereof

Info

Publication number: CN110638718B
Application number: CN201911021652.2A
Authority: CN
Inventors: 张凤娇
Original assignee: Xiamen Xiaoen Yanzhushi Medical Technology Co ltd
Current assignee: Han Xiao
Priority date: 2019-10-25
Filing date: 2019-10-25
Publication date: 2022-06-24
Anticipated expiration: 2039-10-25
Also published as: CN110638718A

Abstract

The invention relates to an anti-aging preparation, an anti-aging composition, and a preparation method and application thereof. The anti-aging preparation comprises the following components in percentage by mass (0.1-4): (0.25-4): (1-8): (0.2-2) hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8. The anti-aging preparation can delay skin cell aging by aiming at the metabolic mechanism of cells, and has good anti-aging effect. Meanwhile, the anti-aging preparation has a mild formula and a good allergy-relieving repair effect, and can inhibit the stimulation of allergens (such as surfactants, preservatives, perfume essences and the like) in skin care products to the skin and keep the skin healthy.

Description

Anti-aging preparation, anti-aging composition, and preparation method and application thereof

Technical Field

The invention relates to the technical field of anti-aging products, in particular to an anti-aging preparation, an anti-aging composition, and a preparation method and application thereof.

Background

Aging is a normal physiological phenomenon that the human body shows with the increase of age, but physical changes caused by aging bring great trouble to people. The most obvious changes in aging are skin problems such as wrinkles, dryness, pigmentation, decreased elasticity, decreased water retention and moisture retention. In particular, the aging phenomenon is now on the rise with the pace of life.

To meet consumer demand for anti-aging, there are more and more anti-aging products and anti-aging methods on the market. Then, these anti-aging products have various qualities, some of which may even rule out addition of hormones, antibiotics, etc., and may exhibit excellent anti-aging properties for a short time, but may have serious adverse effects on the health of consumers in long-term use.

Disclosure of Invention

Based on this, there is a need for an anti-aging preparation which is effective in delaying cell aging, improving wrinkles, and making skin fine and compact and more youthful; meanwhile, the anti-aging preparation has a mild formula and can effectively keep the skin healthy.

In addition, an anti-aging composition containing the anti-aging preparation, and a preparation method and application thereof are also needed to be provided.

An anti-aging formulation characterized by: the composite material comprises the following components in percentage by mass (0.1-4): (0.25-4): (1-8): (0.2-2) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8;

the plant extract comprises the following components in percentage by mass (0.5-2): (1-3): (1.5-2): (3-5): (1-4) radix astragali matsudanae extract, radix sileris extract, calendula extract, albizia flower extract and rhizoma gastrodiae extract.

In one embodiment, the anti-aging preparation comprises the following components in percentage by mass (0.8-2): (0.5-1.5): (1-4): (0.5-1) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8;

the plant extract comprises the following components in percentage by mass (0.8-1.5): (1.5-2.5): (1.5-1.8): (3-4): (2-3.5) radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, and rhizoma Gastrodiae extract.

An anti-aging composition comprises the following raw materials in percentage by mass:

1.55-18% of the anti-aging preparation, 0.05-0.85% of the thickening agent, 2.11-16.1% of the humectant, 0.01-0.04% of the neutralizing agent, 0.4-1% of the preservative and 64.01-95.88% of the solvent.

In one embodiment, the anti-aging composition comprises the following raw materials in percentage by mass:

2.8-8.5% of the anti-aging preparation, 0.1-0.4% of the thickening agent, 5-10% of the humectant, 0.01-0.03% of the neutralizing agent, 0.4-0.8% of the preservative and 80.27-91.69% of the solvent.

In one embodiment, the thickening agent is one or more of carbomer, hydroxyethyl cellulose and xanthan gum; and/or the presence of a gas in the gas,

the humectant is one or more of sodium hyaluronate, propylene glycol, butanediol and betaine; and/or the presence of a gas in the gas,

the neutralizing agent is at least one of sodium hydroxide and potassium hydroxide; and/or the presence of a gas in the atmosphere,

the preservative is one or more of caprylyl hydroximic acid, 1, 2-hexanediol and 1, 3-propylene glycol; and/or the presence of a gas in the gas,

the solvent is at least one of water and propylene glycol.

In one embodiment, the thickening agent comprises 0.02-0.3% of carbomer, 0.01-0.2% of hydroxyethyl cellulose and 0.02-0.35% of xanthan gum by mass percent of the anti-aging composition.

In one embodiment, the humectant comprises 0.01-0.1% of sodium hyaluronate, 1-4% of propylene glycol, 1-9% of butanediol and 0.1-3% of betaine by mass percentage of the anti-aging composition.

A method of preparing an anti-aging composition as described in any of the preceding embodiments, comprising the steps of:

mixing the thickening agent and the solvent to obtain a first mixed system;

adjusting the temperature of the first mixed system to 50-70 ℃, and then adding the humectant to obtain a second mixed system;

adjusting the temperature of the second mixed system to 65-80 ℃ and preserving the heat for 20-40 min;

mixing the neutralizing agent with the second mixed system after heat preservation to obtain a third mixed system;

adjusting the temperature of the third mixed system to 10-40 ℃, and mixing the anti-aging preparation, the preservative and the third mixed system.

A skin care formulation comprising an anti-aging formulation as described in any of the preceding embodiments or an anti-aging composition as described in any of the preceding embodiments.

In one embodiment, the skin care product is any one of a facial mask, a skin lotion, a skin milk and a skin cream.

The anti-aging preparation comprises the following components in percentage by mass (0.1-4): (0.25-4): (1-8): (0.2-2) hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8. Within the mass ratio range, the hydrolyzed oat protein, the red yeast rice extract, the plant extract and the acetyl hexapeptide-8 are reasonably compatible and synergistic, so that the content of cortical collagen can be increased, the structural integrity of skin is maintained, the elasticity of skin is kept, the skin is anti-aging and anti-wrinkle, the muscle contraction is weakened, the formation of wrinkles is prevented, the skin cell aging is delayed, and the anti-aging effect is good. Specifically, the anti-aging preparation can remove wrinkles, effectively prevent the wrinkles from regenerating, make the skin firmer, and make the skin fine, smooth and younger. Meanwhile, the anti-aging preparation has a mild formula and a good allergy-relieving repair effect, and can inhibit the stimulation of allergens (such as surfactants, preservatives, perfume essences and the like) in skin care products to the skin and keep the skin healthy.

The anti-aging composition comprises 1.55-18% of the anti-aging preparation, 0.05-0.85% of a thickening agent, 2.11-16.1% of a humectant, 0.01-0.04% of a neutralizer, 0.4-1% of a preservative and 64.01-95.88% of a solvent by mass percent. The anti-aging preparation in the composition has a good anti-aging effect and also has good moisturizing performance and processability when being matched with other components. The anti-aging preparation can inhibit the irritation of the allergen in the composition to the skin, reduce the allergic reaction of the skin, and keep the skin healthy. The thickening agent, the humectant, the neutralizing agent, the preservative, the solvent and the anti-aging preparation supplement each other and act together to provide the composition with good anti-aging performance, processability and usability.

The preparation method of the anti-aging composition adds corresponding raw materials at different temperatures, and the raw materials can be fully mixed and have synergistic effect to form a uniform composition. The preparation method of the anti-aging composition has the advantages of simple equipment and convenient operation.

The skin care product has good anti-aging and anti-allergy effects.

Detailed Description

In order that the invention may be more fully understood, reference will now be made to the accompanying examples. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The embodiment of the invention provides an anti-aging preparation, which comprises the following components in percentage by mass (0.1-4): (0.25-4): (1-8): (0.2-2) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass (0.5-2): (1-3): (1.5-2): (3-5): (1-4) radix astragali matsudanae extract, radix sileris extract, calendula extract, albizia flower extract and rhizoma gastrodiae extract.

In a specific example, the anti-aging formulation is prepared by: according to the mass ratio (0.1-4): (0.25-4): (1-8): (0.2-2) hydrolyzing oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8. Adding the hydrolyzed oat protein into the plant extract under the condition of stirring in a water bath at 40-45 ℃, and uniformly stirring; adding acetyl hexapeptide-8, and stirring uniformly; continuously stirring, cooling to below 40 ℃, adding the red yeast rice extract, stirring for 3-5 min, and cooling to room temperature to obtain the anti-aging preparation.

In the mass ratio range, the anti-aging preparation provided by the embodiment has reasonable compatibility and synergistic effect of the hydrolyzed oat protein, the red yeast rice extract, the plant extract and the acetyl hexapeptide-8, can delay skin cell aging, and has good anti-aging effect. Specifically, the anti-aging preparation can remove wrinkles, effectively prevent the wrinkles from regenerating, make the skin firmer, and make the skin fine, smooth and younger. Meanwhile, the anti-aging preparation has a mild formula and a good allergy-relieving repair effect, and can inhibit the stimulation of allergens (such as surfactants, preservatives, perfume essences and the like) in skin care products to the skin and keep the skin healthy.

Preferably, the red yeast rice extract, the astragalus membranaceus root extract, the saposhnikovia divaricata root extract, the calendula officinalis extract, the albizia julibrissin flower extract and the gastrodia elata root extract are water extracts of corresponding raw materials.

Preferably, the anti-aging preparation is prepared from the following components in percentage by mass (0.1-4): (0.25-4): (1-8): (0.2-2) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass (0.5-2): (1-3): (1.5-2): (3-5): (1-4) radix astragali matsudanae extract, radix sileris extract, calendula extract, albizia flower extract and rhizoma gastrodiae extract.

In a specific example, the anti-aging preparation comprises the following components in a mass ratio of (0.8-2): (0.5-1.5): (1-4): (0.5-1) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass (0.8-1.5): (1.5-2.5): (1.5-1.8): (3-4): (2-3.5) radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, and rhizoma Gastrodiae extract.

Preferably, the anti-aging preparation is prepared from the following components in percentage by mass (0.8-2): (0.5-1.5): (1-4): (0.5-1) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass (0.8-1.5): (1.5-2.5): (1.5-1.8): (3-4): (2-3.5) radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, and rhizoma Gastrodiae extract.

Further preferably, the anti-aging preparation comprises the following components in a mass ratio of 1: 1: 1.5: 1, hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass of 1: 2: 1.5: 3: 3, radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, and rhizoma Gastrodiae extract.

Further preferably, the anti-aging preparation is prepared from 1: 1: 1.5: 1, hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8; the plant extract comprises the following components in percentage by mass of 1: 2: 1.5: 3: 3, radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, and rhizoma Gastrodiae extract.

In a specific example, the plant extract is prepared from the following raw materials in a mass ratio of 1: 2: 1.5: 3: 3: 4: 10 radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, rhizoma Gastrodiae extract, butanediol and water.

The invention also provides an anti-aging composition, which comprises the following raw materials in percentage by mass:

1.55 to 18 percent of the anti-aging preparation, 0.05 to 0.85 percent of thickening agent, 2.11 to 16.1 percent of humectant, 0.01 to 0.04 percent of neutralizer, 0.4 to 1 percent of preservative and 64.01 to 95.88 percent of solvent.

The anti-aging agent of the anti-aging composition of this example works in combination with other ingredients to provide good anti-aging effect and also provide good moisturizing and processing properties. The anti-aging preparation can inhibit the irritation of the allergen in the composition to the skin, reduce the allergic reaction of the skin, and keep the skin healthy. The thickening agent, the humectant, the neutralizing agent, the preservative, the solvent and the anti-aging preparation supplement each other and act together to provide the composition with good anti-aging performance, processability and usability.

Preferably, the anti-aging composition consists of the following raw materials in percentage by mass:

In a specific example, the anti-aging composition comprises the following raw materials in percentage by mass:

2.8 to 8.5 percent of the anti-aging preparation, 0.1 to 0.4 percent of thickening agent, 5 to 10 percent of humectant, 0.01 to 0.03 percent of neutralizer, 0.4 to 0.8 percent of preservative and 80.27 to 91.69 percent of solvent.

Preferably, the anti-aging composition is prepared from the following raw materials in percentage by mass:

4.5 percent of the anti-aging preparation, 0.27 percent of thickening agent, 7.52 percent of humectant, 0.02 percent of neutralizing agent, 0.6 percent of preservative and 87.09 percent of solvent.

In a specific example, the thickener is one or more of carbomer, hydroxyethyl cellulose, and xanthan gum.

In a specific example, the humectant is one or more of sodium hyaluronate, propylene glycol, butylene glycol, and betaine.

In a specific example, the neutralizing agent is at least one of sodium hydroxide and potassium hydroxide.

In a specific example, the preservative is one or more of caprylhydroxamic acid, 1, 2-hexanediol, and 1, 3-propanediol.

In a specific example, the solvent is at least one of water and propylene glycol. Preferably, the solvent is deionized water.

In a specific example, the thickener comprises 0.02 to 0.3 percent of carbomer, 0.01 to 0.2 percent of hydroxyethyl cellulose and 0.02 to 0.35 percent of xanthan gum in percentage by mass of the anti-aging composition. Preferably, the thickener comprises 0.12% carbomer, 0.05% hydroxyethyl cellulose, and 0.1% xanthan gum, as a mass percentage of the anti-aging composition. Further preferably, the thickener is a mixture of carbomer, hydroxyethyl cellulose and xanthan gum.

In a specific example, the moisturizer comprises 0.01 to 0.1 percent of sodium hyaluronate, 1 to 4 percent of propylene glycol, 1 to 9 percent of butanediol and 0.1 to 3 percent of betaine by mass percent of the anti-aging composition. Preferably, the moisturizer comprises 0.02% of sodium hyaluronate, 2% of propylene glycol, 5% of butylene glycol and 0.5% of betaine by mass percentage of the anti-aging composition. Further preferably, the humectant is formed by mixing sodium hyaluronate, propylene glycol, butylene glycol and betaine.

Another embodiment of the present invention further provides a preparation method of the above anti-aging composition, comprising the following steps:

mixing a thickening agent and a solvent to obtain a first mixed system;

adjusting the temperature of the first mixed system to 50-70 ℃, and then adding a humectant to obtain a second mixed system;

mixing a neutralizing agent with the second mixed system after heat preservation to obtain a third mixed system;

adjusting the temperature of the third mixed system to 10-40 ℃, and mixing the anti-aging preparation and the preservative with the third mixed system.

The invention further provides a skin care product.

In a specific example, the skin care product is any one of a facial mask, a skin lotion, a skin milk and a skin cream.

The following are specific examples:

the plant extracts used in examples 1 to 6 and comparative examples 1 to 5 were prepared from the following raw materials in a mass ratio of 1: 2: 1.5: 3: 3: 4: 10 radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, rhizoma Gastrodiae extract, butanediol and water.

Examples 1 to 6 and comparative examples 1 to 5 used preservatives consisting of caprylyl hydroxamic acid, 1, 2-hexanediol and 1, 3-propanediol in a mass ratio of 2: 1: 2, mixing the components.

1. Raw materials for an anti-aging composition.

(1) The raw materials and mass percentages of the anti-aging compositions of examples 1 to 6 are shown in table 1.

TABLE 1

(2) Raw materials for anti-aging compositions of comparative examples 1 to 6.

Comparative example 1 differs from example 2 in that the hydrolysed oat protein of example 2 was replaced by deionised water.

Comparative example 2 is different from example 2 in that the red yeast rice extract in example 2 was replaced with deionized water.

Comparative example 3 is different from example 2 in that acetyl hexapeptide-8 in example 2 is replaced with deionized water.

Comparative example 4 is different from example 2 in that both the hydrolyzed oat protein and red yeast rice extract of example 2 were replaced with deionized water.

Comparative example 5 is different from example 2 in that the hydrolyzed oat protein, red yeast rice extract and acetyl hexapeptide-8 in example 2 were replaced with deionized water.

The composition in comparative example 6 is the facial mask solution in example 1 of chinese patent application No. 201610937644.2.

2. Preparation of an anti-aging composition.

Example 1 an anti-aging composition was prepared by the following method: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 2min under the stirring condition of 1200r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 60 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 75 ℃ and keep the temperature for 30 min. And after heat preservation, cooling the second mixed system to 60 ℃, adding a neutralizing agent, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 30 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 1.

Example 2 an anti-aging composition was prepared by: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 2min under the stirring condition of 1200r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 65 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 75 ℃ and keep the temperature for 30 min. And after heat preservation, cooling the second mixed system to 65 ℃, adding a neutralizing agent, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 30 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 2.

Example 3 an anti-aging composition was prepared by: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 1min under the stirring condition of 1400r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 62 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 70 ℃ and keep the temperature for 30 min. And after heat preservation, cooling the second mixed system to 60 ℃, adding a neutralizing agent, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 25 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 3.

Example 4 an anti-aging composition was prepared by: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 2min under the stirring condition of 1000r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 65 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 70 ℃ and keep the temperature for 25 min. And after heat preservation, cooling the second mixed system to 62 ℃, adding a neutralizer, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 25 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 4.

Example 5 an anti-aging composition was prepared by: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 3min under the stirring condition of 1000r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 65 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 72 ℃ and keep the temperature for 40 min. And after heat preservation, cooling the second mixed system to 65 ℃, adding a neutralizing agent, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 30 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 5.

Example 6 an anti-aging composition was prepared by: adding the thickening agent into deionized water under the stirring condition, and homogenizing for 1.5min under the stirring condition of 1200r/min to obtain a first mixed system. And then heating while stirring, adjusting the temperature of the first mixed system to 65 ℃, and adding a humectant to obtain a second mixed system. Stirring and heating are continued to heat the second mixed system to 72 ℃ and keep the temperature for 25 min. And after heat preservation, cooling the second mixed system to 60 ℃, adding a neutralizer, and uniformly stirring to obtain a third mixed system. And cooling the third mixed system to 30 ℃, adding the anti-aging preparation and the preservative, uniformly stirring, and cooling to room temperature to obtain orange semitransparent liquid, namely the anti-aging composition in the embodiment 6.

Method for preparing the compositions of comparative examples 1 to 5 the method for preparing the anti-aging composition of example 2 is the same.

3. And (4) testing the performance of the composition.

(1) And testing heat resistance and cold resistance.

The compositions obtained in examples 1 to 6 and comparative examples 1 to 6 were diluted 10 times with deionized water, respectively. The pH values of the composition after dilution were:

example 1 to example 6: 5.3, 5.5, 5.0, 5.8, 5.2, 6.0;

comparative examples 1 to 6: 6.6,6.7,6.6,6.8,7.1,6.2.

From the pH data, it is clear that the pH values of the compositions diluted in examples 1 to 6 and comparative examples 1 to 6 are mild and non-irritating, and correspond to the pH environment of human skin.

And (3) heat resistance test: the diluted composition was stored at 45. + -. 2 ℃ for 60 days, and then returned to room temperature, and the appearance and odor of the composition were observed. The results showed that the compositions of examples 1 to 6 were free from any abnormal appearance and odor after being stored at 45. + -. 2 ℃ for 60 days. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor, and the composition of comparative example 6 was cloudy and smelly.

Cold resistance test: the diluted composition was stored at-17. + -. 2 ℃ for 60 days, then returned to room temperature, and the appearance and odor of the composition were observed. The results showed that the compositions of examples 1 to 6 were free from any abnormal appearance and odor after storage at-17. + -. 2 ℃ for 60 days. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor, and the composition of comparative example 6 was cloudy and smelly.

And (3) cycle testing: placing the diluted composition at 45 + -2 deg.C for 24h, then at room temperature for 24h, then at-17 + -2 deg.C for 24h, circulating for 3 times, then recovering to room temperature, and observing appearance and odor of the composition. The results show that the compositions of examples 1 to 6 had no abnormal appearance and odor after the cycle test. The compositions of comparative examples 1 to 5 were not abnormal in appearance and odor, and the composition of comparative example 6 was slightly cloudy in appearance and had an off-flavor.

(2) And testing physical and chemical indexes.

The compositions of examples 1 to 6 and comparative examples 1 to 6 were diluted 10 times with deionized water, respectively, and prepared into masks by the same process. 120 healthy skin volunteers were randomly selected and tested, one group was taken for each 10 persons, each group was taken as a unit, and the test results were obtained by averaging the facial mask samples of test examples 1 to 6 and comparative examples 1 to 6.

The test is carried out according to QB/T2872-2007, the medicine is applied before sleeping every day for 30 days continuously, and the test results are shown in tables 2-4.

Wherein the moisture content of the skin is measured using a skin moisture tester.

Skin elasticity was measured using a skin elasticity tester MPA580 from CK, germany, using a Reviscometer RV600 probe.

The wrinkle, the compactness, the fineness and the glossiness are all measured by a skin detector, and particularly, a Visia skin detector is adopted.

The experience feeling scoring is used for scoring according to the experience degree of a user, the qi and blood improvement effect is scored according to the comparison between the front and the back of the use condition, the total score is 10, the score is good from 8 to 10, the score is general from 6 to 8, and the score of 6 and below is poor experience feeling; the skin color qi and blood improvement effect is evaluated within 1-10 points through observation, 10 points indicate that the improvement effect is the best, and 1 point indicates that the improvement effect is the worst.

TABLE 2

TABLE 3

TABLE 4

As is clear from the results in tables 2 to 4, the compositions of examples 1 to 6 exhibited better moisturizing effects, particularly better effects in improving skin elasticity, improving wrinkles, and the like, than those of comparative examples 1 to 6.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that various changes and modifications can be made by those skilled in the art without departing from the spirit of the invention, and these changes and modifications are all within the scope of the invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. An anti-aging formulation characterized by: the weight ratio of (0.1-4): (0.25-4): (1-8): (0.2-2) preparing hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8;

the plant extract is prepared from the following components in a mass ratio of 1: 2: 1.5: 3: 3: 4: 10 radix astragali extract, radix Saposhnikoviae extract, herba Sidae Rhombifoliae extract, flos Albizziae extract, rhizoma Gastrodiae extract, butanediol and water; the red yeast rice extract, the astragalus membranaceus root extract, the divaricate saposhnikovia root extract, the calendula officinalis extract, the albizia flower extract and the gastrodia elata root extract are water extracts of corresponding raw materials.

2. The anti-aging formulation of claim 1, wherein: the weight ratio of (0.8-2): (0.5-1.5): (1-4): (0.5-1) hydrolyzed oat protein, red yeast rice extract, plant extract and acetyl hexapeptide-8.

3. An anti-aging composition characterized by: the material comprises the following raw materials in percentage by mass:

the anti-aging preparation of any one of claims 1-2, 1.55-18%, a thickener, 0.05-0.85%, a humectant, 2.11-16.1%, a neutralizer, 0.01-0.04%, a preservative, 0.4-1%, and a solvent, 64.01-95.88%.

4. The anti-aging composition of claim 3, wherein: the material comprises the following raw materials in percentage by mass:

5. The anti-aging composition according to any one of claims 3 to 4, wherein: the thickening agent is one or more of carbomer, hydroxyethyl cellulose and xanthan gum; and/or the presence of a gas in the atmosphere,

the neutralizing agent is at least one of sodium hydroxide and potassium hydroxide; and/or the presence of a gas in the gas,

the solvent is at least one of water and propylene glycol.

6. The anti-aging composition according to any one of claims 3 to 4, wherein: the anti-aging composition comprises, by mass, 0.02% -0.3% of carbomer, 0.01% -0.2% of hydroxyethyl cellulose and 0.02% -0.35% of xanthan gum.

7. The anti-aging composition according to any one of claims 3 to 4, wherein: the anti-aging composition comprises, by mass, 0.01-0.1% of sodium hyaluronate, 1-4% of propylene glycol, 1-9% of butanediol and 0.1-3% of betaine.

8. A method of preparing the anti-aging composition according to any one of claims 3 to 7, characterized in that: the method comprises the following steps:

mixing the thickening agent and the solvent to obtain a first mixed system;

mixing the neutralizer with the second mixed system after heat preservation to obtain a third mixed system;

9. A skin care product characterized by: comprising the anti-aging formulation according to any one of claims 1 to 2 or the anti-aging composition according to any one of claims 3 to 7.

10. The skin care product of claim 9, wherein: the skin care product is any one of facial mask, skin lotion, skin milk and skin cream.