It is a kind of to resist the composition for doing quick Chinese medical extract and preparation method and in cosmetics
Application
Technical field
The invention belongs to a kind of composition of cosmetic composition technical field, more particularly to a kind of anti-do quick traditional Chinese medicine extraction
The composition and preparation method of object and the application in cosmetics.
Background technique
Dry skin, easy allergy are the phenomenon that having dry skin easy sensitization as caused by internal factor and external factor.Human body
Skin with the variation of external environment, especially winter skin water content decline, the drying of skin can be caused;In addition with
Cosmetics improper use, causes skin barrier function to decline, and the immunity of skin weakens, and causes skin to be easier allergy dry.
Furthermore with advancing age, skin function is faded, and skin metabolism slows down, and repairs power decline, the water content of skin by
Gradually reduce, so drying easily occurs in the skin of people, itch plays the symptoms such as dry hide, it is especially relatively conventional in middle coming year crowd,
Seriously affect daily life.
It is commercially available it is anti-to do quick raw material type less, and more is all synthesis material, is easier to cause the discomfort of skin, and
And function and effect are not significant.So developing a kind of anti-quick traditional Chinese medicine extraction composition is done with great market prospects.
Summary of the invention
Resist it is an object of that present invention to provide one kind and does quick traditional Chinese medicine extraction composition.
It is an object of that present invention to provide a kind of mild inirritative traditional Chinese medicine extraction compositions.
Further aim of the present invention is to provide a kind of anti-dry sensitization cosmetic compositions.
Further aim of the present invention, which is to provide, a kind of anti-does quick extraction preparation method of composition.
Further aim of the present invention is to provide a kind of containing the anti-preparation method for doing quick extraction composition cosmetics.
Further aim of the present invention is to provide a kind of anti-application for doing quick extraction composition in cosmetics.
In order to solve the above technical problems, the present invention, which devises, a kind of does the quick Chinese medical extract for extracting composition with anti-
Formula.It include radix polygonati officinalis (Polygonatum odoratum (Mill.) Druce), Radix Ophiopogonis in traditional Chinese medicine extraction composition
(Ophiopogon japonicus (Linn.f.) Ker-Gawl.), Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch), hardship
Join five kinds of (Sophora flavescens), folium artemisiae argyi (Folium Artemisiae argyi) Chinese medicines, is respectively provided with following function
Effect:
(1) radix polygonati officinalis:It is sweet, it is slightly cold;It attaches to the lung and stomach meridians.Perennial herb medicinal and edible plant, the yin-nourishing of radix polygonati officinalis tool are moisturized, clearly
Heat is promoted the production of body fluid, cough-relieving and other effects.Research shows that radix polygonati officinalis has the function of to increase immunocompetence, anti-aging and anti-oxidant etc..Radix polygonati officinalis
In the polysaccharide that contains there is preferable moisture retention, skin moisture content can be effectively improved, slow down the lost rate of moisture, and energy
Interior free yl is removed, inhibits the formation of melanocyte, plays the effect of moistening skin and eliminating spot.
(2) Radix Ophiopogonis:It is sweet, slight bitter, slightly cold;Return heart, lung, stomach meridian.For common enriching yin Chinese medicine,《Sheng Nong's herbal classic》By Radix Ophiopogonis
It is classified as the top grade of Yin nourishing and lung moistening, says its " long term usage is made light of one's life by commiting suicide, not old not hungry ".Wherein ophiopogonin D enhances cell viability, delays to decline
Always;Ophiopogonpolysaccharide can absorb moisture from atmosphere makes skin keep wetting, can also absorb moisture from deep skin, reach moisturizing
Effect.
(3) Radix Glycyrrhizae:Sweet and neutral;Return heart, lung, spleen, stomach meridian.Radix Glycyrrhizae can be with antibacterial, anti-inflammatory, antiallergy, reparation, adjusting skin
The formation of melanin.
(4) kuh-seng:Hardship is trembled with fear;Return heart, liver, stomach, large intestine, bladder meridian.There are heat-clearing, eliminating dampness and other effects, there are also immunological regulation,
The effects of anti-inflammatory.
(5) folium artemisiae argyi:It is pungent, bitter, temperature;Liver,spleen,kidney is returned to pass through.The effects of eliminating cold to stop pain, warming channel for arresting bleeding, at the same have it is anti-inflammatory, resist
Bacterium, antiallergic and other effects.
The present invention is anti-to do the component that quick traditional Chinese medicine extraction composition specific formula includes following parts by weight:32-45 parts of radix polygonati officinalis,
Radix Ophiopogonis 25-35 part, 15-24 parts of Radix Glycyrrhizae, 9-13 parts of kuh-seng, 3-8 parts of folium artemisiae argyi.
Anti- the group that quick traditional Chinese medicine extraction composition includes following parts by weight is done as a preferred embodiment, described
Point:34-43 parts of radix polygonati officinalis, Radix Ophiopogonis 27-33 part, 17-23 parts of Radix Glycyrrhizae, 10-13 parts of kuh-seng, 3-7 parts of folium artemisiae argyi.
As another preferred embodiment, the traditional Chinese medicine extraction composition includes the component of following parts by weight:It is beautiful
36-41 parts of bamboo, Radix Ophiopogonis 28-32 part, 19-23 parts of Radix Glycyrrhizae, 10-12 parts of kuh-seng, 2-7 parts of folium artemisiae argyi.
Embodiment as a further preference, the traditional Chinese medicine extraction composition include the component of following parts by weight:It is beautiful
33 parts of bamboo, 31 parts of Radix Ophiopogonis, 18 parts of Radix Glycyrrhizae, 12 parts of kuh-seng, 6 parts of folium artemisiae argyi;Or it is preferred, 36 parts of radix polygonati officinalis, 30 parts of Radix Ophiopogonis, Radix Glycyrrhizae 18
Part, 11 parts of kuh-seng, 5 parts of folium artemisiae argyi;Or it is preferred, 39 parts of radix polygonati officinalis, Radix Ophiopogonis 28,19 parts of Radix Glycyrrhizae, 10 parts of kuh-seng, 4 parts of folium artemisiae argyi.
Combinations of the above object can be used for skin it is anti-do it is quick.
On the other hand, the present invention also provides a kind of preparation method for preparing above-mentioned traditional Chinese medicine extraction composition, including it is following
Step:
(1) medicinal material pre-processes:Each Chinese medicine material is weighed, is crushed, grinding is uniformly mixed after sieving;
(2) it extracts:Medicinal material mixture is added in 60%~75% ethanol water, is impregnated, temperature is 30~40
DEG C, ultrasound, then circumfluence distillation, obtains extracting solution;
(3) it purifies:Extracting solution passes through high speed centrifugation, filtering, vacuum concentration, is precipitated with 75~85% ethanol water,
Sediment freeze-drying.
Traditional Chinese medicine extraction composition of the invention is mainly used in cosmetics, but specific cosmetics do not limit especially
System.Cosmetics can be shower cream, facial cleanser or Essence;But it is particularly preferred, it is shower cream.
There are also on the one hand, the present invention provides a kind of cosmetic formulations containing above-mentioned traditional Chinese medicine extraction composition, containing described
The weight percent of composition is 0.05-18%.
As a preferred embodiment, the weight percent in cosmetics containing the composition is 5-12%.
Still further aspect, it to include following parts by weight that the present invention provides a kind of shower creams containing above-mentioned Chinese medicine composition
Component:7-14 parts of laurel alcohol sulfuric ester ammonium, 5-12 parts of laureth sodium sulfovinate, 2-8 parts of Cocoamidopropyl betaine,
0.5-1.5 parts of coconut oleoyl amine MEA, 1-5 parts of glycerol, 1-3 parts of glycol distearate, hydroxypropyl methyl cellulose 0.3-0.8
Part, 0.01-0.3 parts of hyaluronic acid, 1-3 parts of D-sorbite, 0.5-1.5 parts of sodium chloride, 0.3-1 parts of Phenoxyethanol, sodium benzoate
0.2-0.3 parts, 0.05-18 parts of traditional Chinese medicine extraction composition, 62.5-81.2 parts of water.
The beneficial effect that the present invention obtains:
The above several drugs share, and have and moisten moisturizing, antibacterial, antiallergic, antipruritic and other effects, do quick extraction group for this
Close object addition in cosmetics, can resist dry skin, resist it is micro- itch, moisturizing, nourish skin be integrated, by reparation skin it is natural
Barrier enhances skin immunity, improves the moisture-retaining capacity of skin, skin of releiving.Addition is in cosmetics, and anti-to do quick effect aobvious
It writes.
In the prior art, discovery plurality of Chinese extract has the effect of moist moisturizing, antibacterial, antiallergic.But these
When Chinese medical extract is used alone, moist moisturizing, antibacterial, antiallergic effect are unobvious, it is difficult to meet to resist and do the needs of quick.Although mesh
The composition of the preceding Chinese medical extract for also thering is small part to compound, but anti-do that quick effect is unobvious, some even decline;This hair
It is bright after having screened a large amount of compounded formula, discovery is multiple when the extract of radix polygonati officinalis, Radix Ophiopogonis, Radix Glycyrrhizae, kuh-seng, folium artemisiae argyi this five kinds of Chinese medicines
After matching, it can obtain significantly to resist and do quick effect, this five kinds of ingredients play the role of synergy.By Chinese medical extract of the invention
Apply in the cosmetics such as shower cream, it is anti-that to do quick effect obvious, and by it is experimentally confirmed that when radix polygonati officinalis, Radix Ophiopogonis, Radix Glycyrrhizae,
Kuh-seng, the composition of folium artemisiae argyi are nonirritant to human body.
Detailed description of the invention
Fig. 1 is single medicinal material extract and shower cream made of traditional Chinese medicine extract composition in antipruritic, the anti-scales of skin that peel off, tight
The relational graph that three aspect of degree is tested.
Fig. 2 is kinds of traditional Chinese medicines extract and shower cream made of traditional Chinese medicine extract composition in antipruritic, the anti-scales of skin that peel off, tight
Spend tripartite's relation of plane figure.
Fig. 3 is that single medicinal material extract, kinds of traditional Chinese medicines extract are done shower cream made of quick Chinese medical extract and protected with resisting
Relational graph in terms of wet test.
Specific embodiment
Technical solution of the present invention is further illustrated below by way of specific embodiment, and specific embodiment does not represent to this hair
The limitation of bright protection scope.Other people according to the present invention theory made it is some it is nonessential modification and adjustment still fall within this hair
Bright protection scope.
Embodiment 1 is anti-to do quick traditional Chinese medicine extraction composition (1) formula and preparation method
It is a kind of have effects that it is anti-do quick traditional Chinese medicine extraction composition, the Chinese medicine of the parts by weight shown in table (1) forms
1 composition of table (1)
The steps included are as follows for traditional Chinese medicine extraction preparation method of composition:
(1) 5 kinds of total 100g of Chinese medicine are taken by the parts by weight relationship of table 1, crushed, 10 meshes are crossed in grinding, and then mixing is equal
It is even, for use.
(2) 0.8L is added, volume ratio is 65% ethanol water as Extraction solvent, impregnates 1h, and then temperature is 35 DEG C,
Ultrasonic 30min, circumfluence distillation 3 times, each 2h obtains extracting solution.
(3) extracting solution is passed through into high speed centrifugation, filtered, then vacuum concentration is precipitated, precipitating with 80% ethanol water
Object freeze-drying.
Embodiment 2 is anti-to do quick traditional Chinese medicine extraction composition (2) formula and preparation method
Composition (2) formula such as table 2, the preparation method is the same as that of Example 1
2 composition of table (2)
Component |
Parts by weight |
Radix polygonati officinalis |
36 |
Radix Ophiopogonis |
30 |
Radix Glycyrrhizae |
18 |
Kuh-seng |
11 |
Folium artemisiae argyi |
5 |
Embodiment 3 is anti-to do quick traditional Chinese medicine extraction composition (3) formula and preparation method
Composition (3) formula such as table 3, the preparation method is the same as that of Example 1
3 composition of table (3)
Component |
Parts by weight |
Radix polygonati officinalis |
39 |
Radix Ophiopogonis |
28 |
Radix Glycyrrhizae |
19 |
Kuh-seng |
10 |
Folium artemisiae argyi |
4 |
Embodiment 4 is anti-to do quick shower cream
Table 4 is anti-to do quick shower cream
The above-mentioned anti-preparation method for doing quick shower cream is as follows:
(1) laureth sodium sulfovinate is added to the water, after being heated to 75-85 DEG C of dissolution, laurel alcohol sulfuric ester is added
Ammonium, stirring and dissolving.
(2) hydroxypropyl methyl cellulose glycerol is pre-dispersed, it is then added in (1), is dispersed with stirring dissolution, it is to be dissolved
Afterwards, coconut oleoyl amine MEA, glycol distearate, sodium benzoate is added, dissolution is added, heat preservation cools down after 15 minutes.
(3) 50 DEG C of additions Cocoamidopropyl betaines, sodium chloride are cooled to, 40 DEG C of addition Phenoxyethanols are cooled to and are resisted
Quick traditional Chinese medicine extraction composition (shower cream 4 does not add composition) is done, persistently stirs ten minutes, vacuumizes, it is qualified to examine, discharging.
The preparation of 1 single medicinal material extract of comparative example
The extract of 5 single medicinal material of table
Contrast groups 1-5 other than traditional Chinese medicine ingredients are respectively radix polygonati officinalis, Radix Ophiopogonis, Radix Glycyrrhizae, kuh-seng, folium artemisiae argyi, preparation method all with
Embodiment 1 is identical.To which 100g Rhizoma Polygonati Odorati extract, 100g ophiopogon japonicus extract, 100g licorice, 100g kuh-seng be made respectively
Extract, 100g Folium Artemisiae Argyi extract.
Shower cream 5-9 is prepared using the extract of contrast groups 1-5.Wherein, in addition to extract is respectively single medicament extract
In addition, the type of remaining component, content and preparation method are the same as shower cream 1.
The preparation of 2 kinds of traditional Chinese medicines extract of comparative example
Contrast groups 6:Difference from Example 1 is contrast groups 6 not comprising Folium Artemisiae Argyi extract.
Contrast groups 7:Difference from Example 1 is contrast groups 7 not comprising shrubby sophora extract.
Contrast groups 8:Difference from Example 1 is contrast groups 8 not comprising ophiopogon japonicus extract.
Contrast groups 9:Difference from Example 1 is contrast groups 9 not comprising licorice.
Contrast groups 10:Difference from Example 1 is contrast groups 10 not comprising Rhizoma Polygonati Odorati extract.
For contrast groups 6-10 other than traditional Chinese medicine ingredients are different from embodiment 1, preparation method, Chinese medicine number are same as Example 1.
To which five parts of different extracts be made respectively.
Shower cream 10-14 is prepared using the extract of contrast groups 6-10.Wherein, other than extract is different, remaining component
With type, content and preparation method with shower cream 1.
5 human body patch test of embodiment
1. tested material:4 kinds in the embodiment of the present invention 4 anti-to do quick shower cream, i.e., shower cream 1, shower cream 2, shower cream 3,
Shower cream 4;
2. subject:Totally 60 people, wherein male 25, the age 20-55 years old, meets subject and volunteer inclusion criteria by female 35;
3. test method:Using blocking test method, tested material is placed in suitable patch examination device, by it with low cause
Sensitive tape is pasted on the arm song side of subject, is gently pressed with palm and is allowed to uniformly be pasted on skin, continues 24 hours;Blank
Control group indicates that subject does not use shower cream;
4. observing result:Remove tested device after 24 hours respectively, 0.5h, for 24 hours, dermoreaction is observed after 48h, record is anti-
Answer result.The adverse reaction grade of skin is shown in Table 6, and test result is shown in Table 7.
6 skin closure type patch test dermoreaction grade scale of table
7 human skin patch test result of table
The result shows that shower cream 1, shower cream 2, shower cream 3 have 0 skin adverse reaction occur in 60 subjects, wash one's hair
Bath lotion 4 has 51 grade of adverse reactions, 1 second level adverse reaction, and illustrating the embodiment of the present invention 4 anti-, to do quick shower cream stingless safely
Swash, the anti-composition for doing quick Chinese medical extract, which can play skin significantly to resist, does quick effect.
6 instrument efficacy assessment of embodiment, human body evaluation
Selecting 300 can obviously observe that dry skin easily plays the small scales of skin that peel off, and the volunteer of easily sensitive, easy itch passes through
After entering group, every group is 20 volunteers, persistently uses 4 weeks, finally obtains result as shown in table 8.
Table 8:The effect of embodiment and comparative example, assesses test result
Fig. 1, Fig. 2, Fig. 3 are obtained according to the data in table 8.
Fig. 1 is single medicinal material extract and shower cream made of traditional Chinese medicine extract composition in antipruritic, the anti-scales of skin that peel off, tight
The relational graph that three aspect of degree is tested.
Fig. 2 is kinds of traditional Chinese medicines extract and shower cream made of traditional Chinese medicine extract composition in antipruritic, the anti-scales of skin that peel off, tight
Spend tripartite's relation of plane figure.
Fig. 3, which is single medicinal material extract and kinds of traditional Chinese medicines extract, to be done shower cream made of quick Chinese medical extract and is protecting with resisting
Relational graph in terms of wet test.
By the above experimental data and Fig. 1-3 it is found that the shower cream 1-3 in embodiment 4 is compared with shower cream 4, moistening effect
It increases significantly, and improves significantly in terms of itch degree, the scales of skin that peel off, illustrate that Chinese medical extract has significantly to resist and do quick effect
Fruit.
Compared with the 10-14 in the shower cream 5-9 and comparative example 2 in comparative example 1, the shower cream 1-3 of embodiment 4 has been used
Later, the moistening effect of skin is significantly improved, and itch degree is substantially reduced, and the scales of skin that peel off improves obvious, foaming abundancy, aspiration
Person does not experience tight feeling.Illustrate to resist and does quick traditional Chinese medicine extraction composition than single medicinal material extract or traditional Chinese medicine extraction composition
Any four combination have it is more significant it is anti-do quick effect, foam is more excellent, and moistening effect is more preferable.In addition, of the invention washes one's hair
Bath lotion 1-3 compares than commercially available shower cream, uses obvious effect.
These results suggest that traditional Chinese medicine extract composition of the invention have effects that it is anti-do quick, and have between several components
There is synergy.
The preferred embodiment of the present invention has been described in detail above, be inventor take a large amount of manpower financial capacities and when
Between, test of many times draw it will be appreciated that, as a result, the ordinary skill of this field without creative work can according to this
Many modifications and variations are made in the design of invention.