CN110151900A - A kind of extract oral solution and preparation method thereof for poultry bronchial embolization - Google Patents

A kind of extract oral solution and preparation method thereof for poultry bronchial embolization Download PDF

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Publication number
CN110151900A
CN110151900A CN201910624605.0A CN201910624605A CN110151900A CN 110151900 A CN110151900 A CN 110151900A CN 201910624605 A CN201910624605 A CN 201910624605A CN 110151900 A CN110151900 A CN 110151900A
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parts
poultry
sweet
radix
chinese medicine
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CN110151900B (en
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毕振东
周峰
要瑞丽
赵丽娜
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SRICK (TIANJIN) BIO-TECHNOLOGY Co Ltd
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SRICK (TIANJIN) BIO-TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/42Cucurbitaceae (Cucumber family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

A kind of extract oral solution for poultry bronchial embolization, it is characterised in that the ingredient of the traditional Chinese medicine oral liquid is by sweet aster 6-12 parts;Sweet loguat leaf 6-12 parts;6-12 parts of radix scrophulariae;Fry semen armeniacae amarae 3-9 parts;3-9 parts of prepared RHIZOMA PINELLIZE without adju-vant;3-9 parts of mulberry leaf;3-9 parts of the flower bud of lily magnolia;3-9 parts of Poria cocos;3-9 parts of Bombyx Batryticatus (parched);3-9 parts of radix scutellariae;3-9 parts of Snakegourd Fruit;3-9 parts of fritillaria thunbergii;3-9 parts of the root bark of Chinese wolf-berry;1-6 parts of blackberry lily;1-6 parts of cicada slough;1-5 parts of Herba ephedrae;1-5 parts of Radix Glycyrrhizae compositions.The present invention utilizes traditional Chinese medical theory knowledge, reasonable compatibility, the prevention and control suitable for respiratory tract bronchial embolization symptom caused by the various season a variety of causes of poultry according to poultry growth characteristic.And preparation method is simple, operation is easy, is suitble to large-scale production, avoids cross contamination and microbial contamination.The abuse and suprainfection for substituting the chemicals such as part antibiotic and virus, prevent the abuse phenomenon of domestic market antibiotic.

Description

A kind of extract oral solution and preparation method thereof for poultry bronchial embolization
Technical field
The present invention relates to poultry liquid fields, and in particular to a kind of extract oral solution for poultry bronchial embolization Agent and preparation method thereof.
Background technique
Two season of winter in spring is fowl cough high-incidence season, and two season of winter in spring is dry, and temperature is sometimes hot and sometimes cold, and day and night temperature is big, Various stress factors increase, it is easy to which the integrality for destroying upper respiratory tract mucous membrane is allowed to the ability decline that rejects, leads to various cause of diseases Body, which is taken advantage of a weak point, to be caused to fall ill, and Abwehrkraft des Koepers is caused to decline, and when having cold stress, cold airflow stimulates respiratory mucosa, at this time Mucous membrane is easy to happen the inflammation such as oedema, hyperemia, causes to have mucus or sputum inside poultry tracheae, has noise in breathing, draw Symptoms of respiratory disease is played, so as to cause poultry bronchial embolization, poultry is difficult to expectoration, and the feelings such as death by suffocation are caused when serious Condition, mucus or sputum are ubiquitous, almost always throughout poultry, therefore remove mucus, sputum, protect poultry bronchus and breathing System makes mucus, sputum, foreign matter, embolism etc. be easy to expectoration and excretes, and the generation for preventing and treating poultry respiratory embolism is especially heavy It wants.
Summary of the invention
In view of the above-mentioned problems, the purpose of the present invention is to provide a kind of extract oral solution for poultry bronchial embolization Agent, it is characterised in that the ingredient of the traditional Chinese medicine oral liquid by sweet aster, sweet loguat leaf, radix scrophulariae, fry semen armeniacae amarae, prepared RHIZOMA PINELLIZE without adju-vant, mulberry leaf, The flower bud of lily magnolia, Poria cocos, Bombyx Batryticatus (parched), radix scutellariae, Snakegourd Fruit, fritillaria thunbergii, the root bark of Chinese wolf-berry, blackberry lily, cicada slough, Herba ephedrae, Radix Glycyrrhizae composition.
Further, the traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: sweet aster 6-12 parts;Sweet loquat 6-12 parts of leaf;6-12 parts of radix scrophulariae;Fry semen armeniacae amarae 3-9 parts;3-9 parts of prepared RHIZOMA PINELLIZE without adju-vant;3-9 parts of mulberry leaf;3-9 parts of the flower bud of lily magnolia;3-9 parts of Poria cocos; 3-9 parts of Bombyx Batryticatus (parched);3-9 parts of radix scutellariae;3-9 parts of Snakegourd Fruit;3-9 parts of fritillaria thunbergii;3-9 parts of the root bark of Chinese wolf-berry;1-6 parts of blackberry lily;1-6 parts of cicada slough; 1-5 parts of Herba ephedrae;1-5 parts of Radix Glycyrrhizae.
Further, the traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: 10 parts of sweet aster, sweet loguat leaf 9 parts, 9 parts of radix scrophulariae, 6 parts of semen armeniacae amarae of stir-fry, 6 parts of prepared RHIZOMA PINELLIZE without adju-vant, 6 parts of mulberry leaf, 6 parts of the flower bud of lily magnolia, 6 parts of Poria cocos, 6 parts of Bombyx Batryticatus (parched), 6 parts of radix scutellariae, 6 parts of Snakegourd Fruit, 6 parts of fritillaria thunbergii, 6 parts of the root bark of Chinese wolf-berry, 3 parts of blackberry lily, 3 parts of cicada slough, 3 parts of Herba ephedrae, 3 parts of Radix Glycyrrhizae.
Further, the prepared slices of Chinese crude drugs are mixed in proportion, adds 3-5 times of purified water for the first time, impregnated 5 hours, heating is boiled It boils and is kept for slightly boiled 30 minutes, siphon supernatant, second plus 2-3 times of purified water, heating boil and kept for slightly boiled 30 minutes, rainbow Clear liquid is sucted, the dregs of a decoction merge filtering and concentrating into specific gravity with 2 supernatants after squeezing be 1.15-1.35, and pH value is controlled in 5.0- 7.0, add purified water to full dose, 100ml/ bottles of oral administration solutions are made in packing, capping, labeling, packaging.
The present invention has the advantages that
1, the present invention is suitable for poultry various seasons using traditional Chinese medical theory knowledge reasonable compatibility according to poultry growth characteristic Save the prevention and control of respiratory tract bronchial embolization symptom caused by a variety of causes.
2, preparation method is simple, operation is easy, is suitble to large-scale production, avoids cross contamination and microbial contamination. The abuse and suprainfection of the chemicals such as substitute antibiotics and virus prevent domestic market abuse of antibiotics phenomenon.
3, the present invention be used for poultry bronchial embolization emergency treatment, and for poultry respiratory infection, bronchitis, Cough long be not cured, bronchial embolization caused by lung heat, phlegm contain high fever, acute respiratory disease, chronic respiratory disease, flu is with cough It coughs fever, the emergency treatment of the dead symptoms such as only.
Specific embodiment
The present invention provides a kind of extract oral solution for poultry bronchial embolization, the ingredient of traditional Chinese medicine oral liquid by Sweet aster, sweet loguat leaf, radix scrophulariae, fry semen armeniacae amarae, prepared RHIZOMA PINELLIZE without adju-vant, mulberry leaf, the flower bud of lily magnolia, Poria cocos, Bombyx Batryticatus (parched), radix scutellariae, Snakegourd Fruit, fritillaria thunbergii, The root bark of Chinese wolf-berry, blackberry lily, cicada slough, Herba ephedrae, Radix Glycyrrhizae composition.
Sweet aster, warm-natured, acrid flavour, hardship are distributed in lung channel.With moistening lung to lower qi, stopping coughing and removing phlegm.It breathes with cough for abundant expectoration, new chronic cough It coughs, overstrain cough hemoptysis.Sweet aster has very strong warm lung to act on, moreover it is possible to which lower gas dissolving phlegm can play tracheaectasy, the diluted work of sputum With, and sputum can be accelerated and foreign matter excretes.Main component is shionone (C30H50O)。
Sweet loguat leaf, cold nature, bitter attach to the lung and stomach meridians.With clearing lung and relieving cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough with lung heat, gas Inverse asthma is anxious, and stomach energy is vomitted inverse, dysphoria and thirsty, preventing phlegm from forming and stopping coughing, the symptoms such as throat itch.Main component is seven pier tartaric acid (C30H48O3) and Ursolic acid (C30H48O3)。
Radix scrophulariae, cold nature is sweet in flavor, bitter, salty, return lung, stomach, kidney channel, has clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass.With Enter ying blood, temperature macular eruption, consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, carbuncle sore tumefacting virus in heat.It is main Wanting ingredient is harpagide (C15H24O10) and harpagoside (C24H30O11)。
Semen armeniacae amarae is fried, slightly warm in nature, bitter, return lung, large intestine channel have sending down abnormally ascending relieving cough and asthma, relax bowel and defecation.For gas of coughing Asthma, fullness sensation in chest abundant expectoration, dry constipation of intestines.Main component is amarogentin (C20H27NO11)。
Prepared RHIZOMA PINELLIZE without adju-vant, warm-natured, acrid flavour, returns spleen, stomach, lung channel have eliminating dampness and eliminating phlegm.For damp-phlegm syndrome, gastral cavilty feeling of fullness, sputum Cohesion, coughs up and can not spit.Main component is total acid, predominantly succinic acid (C4H6O4)。
Mulberry leaf, cold in nature, sweet in flavor, bitter, return lung, Liver Channel have dispelling wind and heat from the body, and clearing away the lungheat and moisturizing is clear liver and improved vision.For wind-heat sense It emits, lung-heat type cough, dizzy headache, red eyes and dim-sighted.Main component is rutin (C27H30O16)。
The flower bud of lily magnolia, warm-natured, acrid flavour attaches to the lung and stomach meridians, and has dispersing wind and cold, clearing the nasal passage.For chill headache, nasal congestion, nose Deep pool.Main component is magnelin (C23H28O7)。
Poria cocos, property is light, flat, sweet in flavor, return heart, lung, spleen, kidney channel, has clearing damp and promoting diuresis, invigorating the spleen, calming heart.It is urinated for oedema Less, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea are had no peace of mind.
Bombyx Batryticatus (parched), mild-natured, taste is salty, pungent, returns liver, lung, stomach meridian, has Inflammation Zhijing, wind-expelling pain-stopping, reducing phlegm and resolving masses.For Liver wind presss from both sides phlegm, headache due to pathogenic wind-heat, hot eyes pharyngalgia.
Radix scutellariae, cold in nature, bitter, return lung, gallbladder, spleen, large intestine, small intestinl channel have heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis.For Damp-warm syndrome, summer-heat and damp, chest tightness and emesis, damp and hot feeling of fullness, dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head, carbuncle sore tumefacting virus.Mainly at It is divided into scutelloside (C21H18O11)。
Snakegourd Fruit, cold in nature, sweet in flavor, slight bitter, return lung, stomach, large intestine channel have clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizing dryness and lubricating intestine.With In cough with lung heat, yellow and thick phlegm, chest impediment and cardialgia, pulmonary abscess, acute appendicitis, constipation.
Fritillaria thunbergii, cold in nature, bitter, return lung, the heart channel of Hang-Shaoyin have clearing heat, eliminating phlegm, relieving cough, and detoxicating and resolving a mass disappears carbuncle.For wind-heat cough It coughs, phlegm-fire cough, pulmonary abscess, acute mastitis, scrofula, sore.Main component is peimine (C27H45NO3) and Peininine (C27H43NO3)。
The root bark of Chinese wolf-berry, cold in nature, sweet in flavor, return lung, liver and kidney channel have cool blood except steaming, clearing lung-heat fall fire.For deficiency of Yin hectic fever, hectic fever due to yin Night sweat, cough with lung heat, Heat Diabetes.
Blackberry lily, cold in nature, bitter is distributed in lung channel, has clearing heat and detoxicating, anti-inflammatory, relieving sore-throat.For heat toxin convulsive seizure due to phlegm-fire pent-up, throat is swollen Bitterly, accumulation and obstruction of sputum, cough and asthma.Main component is irisflorentin (C20H18O8)。
Cicada slough, cold in nature, sweet in flavor, return lung, Liver Channel have dispelling wind and heat from the body, relieving sore-throat, promoting eruption, removing nebula, spasmolysis.For wind Thermal sensation emits, and pharyngalgia is silent, cataract.
Herba ephedrae, warm-natured, acrid flavour, return lung, bladder meridian have sweating cold dispelling, freeing lung and relieving asthma, inducing diuresis for removing edema.For chill Flu, uncomfortable in chest to breath with cough, geomantic omen edema.Herba ephedrae moistening lung to arrest cough is chiefly used in characterization and has solved, asthma and cough.Main component is hydrochloric acid Ephedrine (C10H15) and pseudoephedrine hydrochloride (C NOHCl10H15NO·HCl)。
Radix Glycyrrhizae, mild-natured, sweet in flavor, return heart, lung, spleen, stomach meridian have and invigorate the spleen and benefit qi, clearing heat and detoxicating, remove phlegm and relieving cough, emergency is stopped Bitterly, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, carbuncle sore tumefacting virus, alleviate drug toxicity it is strong Property.Main component is liquiritin (C21H22O9) and glycyrrhizic acid (C42H62O16)。
Embodiment one:
Traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: sweet aster 80g;Sweet loguat leaf 80g parts;Radix scrophulariae 80g;Fry semen armeniacae amarae 40g;Prepared RHIZOMA PINELLIZE without adju-vant 40g;Mulberry leaf 40g;Flower bud of lily magnolia 40g;Poria cocos 40g;Bombyx Batryticatus (parched) 40g;Radix scutellariae 40g;Snakegourd Fruit 40g; Fritillaria thunbergii 40g;Root bark of Chinese wolf-berry 40g;Blackberry lily 20g;Cicada slough 20g;Herba ephedrae 20g;Radix Glycyrrhizae 15g.
The prepared slices of Chinese crude drugs are mixed in proportion, for the first time plus 4 times of purified waters, immersion 5 hours, heating boil and keep micro- Boiling 30 minutes, siphon supernatant, second plus 2 times of purified waters, heating are boiled and are kept for slightly boiled 30 minutes, siphon supernatant, medicine Slag merges filtering and concentrating into specific gravity with 2 supernatants after squeezing be 1.21, and adjusting pH value is 6.1, adds purified water to full dose, divides 100ml/ bottles of oral administration solutions are made in dress, capping, labeling, packaging.
Embodiment two:
Traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: sweet aster 100g;Sweet loguat leaf 100g;Radix scrophulariae 100g;Fry semen armeniacae amarae 60g;Prepared RHIZOMA PINELLIZE without adju-vant 60g;Mulberry leaf 60g;Flower bud of lily magnolia 60g;Poria cocos 60g;Bombyx Batryticatus (parched) 60g;Radix scutellariae 60g;Snakegourd Fruit 50g; Fritillaria thunbergii 60g;Root bark of Chinese wolf-berry 40g;Blackberry lily 20g;Cicada slough 20g;Herba ephedrae 25g;Radix Glycyrrhizae 15g.
The prepared slices of Chinese crude drugs are mixed in proportion, for the first time plus 5 times of purified waters, immersion 5 hours, heating boil and keep micro- Boiling 30 minutes, siphon supernatant, second plus 3 times of purified waters, heating are boiled and are kept for slightly boiled 30 minutes, siphon supernatant, medicine Slag merges filtering and concentrating into specific gravity with 2 supernatants after squeezing be 1.19, and adjusting pH value is 6.4, adds purified water to full dose, divides 100ml/ bottles of oral administration solutions are made in dress, capping, labeling, packaging.
Embodiment three:
Traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: sweet aster 120g;Sweet loguat leaf 120g;Radix scrophulariae 120g;Fry semen armeniacae amarae 90g;Prepared RHIZOMA PINELLIZE without adju-vant 90g;Mulberry leaf 90g;Flower bud of lily magnolia 90g;Poria cocos 80g;Bombyx Batryticatus (parched) 80g;Radix scutellariae 80g;Snakegourd Fruit 80g; Fritillaria thunbergii 80g;Root bark of Chinese wolf-berry 80g;Blackberry lily 50g;Cicada slough 50g;Herba ephedrae 40g;Radix Glycyrrhizae 30g.
The prepared slices of Chinese crude drugs are mixed in proportion, for the first time plus 4 times of purified waters, immersion 5 hours, heating boil and keep micro- Boiling 30 minutes, siphon supernatant, second plus 3 times of purified waters, heating are boiled and are kept for slightly boiled 30 minutes, siphon supernatant, medicine Slag merges filtering and concentrating into specific gravity with 2 supernatants after squeezing be 1.28, and adjusting pH value is 6.4, adds purified water to full dose, divides 100ml/ bottles of oral administration solutions are made in dress, capping, labeling, packaging.
Experimental program:
The application of oral solution sample clinically through the invention determines the present invention to poultry respiratory infection, bronchus It is scorching, cough long be not cured, bronchial embolization caused by lung heat, phlegm contain high fever, acute respiratory disease, chronic respiratory disease, flu companion There is the therapeutic effect of cough fever, the dead symptoms such as only.
Test selection age in days is close, and the group of chicken similar in above-mentioned morbidity sign is tested.Using oral solution group of the present invention, double Coptis oral solution group.It routinely requires to carry out feeding management and be immunized.
The control set product of this test of test material is provided by research and development centre, Tianjin Ringpu Bio-technology Co., Ltd., Test specimen: 250ml/ bottles of Shuanghuanglian oral liquid, lot number: 20181203.Implementation group is oral solution of the embodiment of the present invention, 100ml/ Bottle, lot number: 20190102.
Test method control group and test group are all made of the consistent feeding standard of test chicken factory and daily ration.Test group is to prescription Method: the usage and dosage of drinking water administration is: oral solution of the embodiment of the present invention and Shuanghuanglian oral liquid group are watered 200 jin by every bottle, Once a day, drinking-water is concentrated, is used in conjunction 5 days.Compare within medication 5 days chicken group disease incidence, effective percentage, cure rate, the death rate, respiratory tract disease Disease control and recovery situation and the state of mind etc..
Experimental result is detailed in following table:
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into Row equivalent replacement;And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution The range of scheme.

Claims (4)

1. a kind of extract oral solution for poultry bronchial embolization, it is characterised in that the ingredient of the traditional Chinese medicine oral liquid by Sweet aster, sweet loguat leaf, radix scrophulariae, fry semen armeniacae amarae, prepared RHIZOMA PINELLIZE without adju-vant, mulberry leaf, the flower bud of lily magnolia, Poria cocos, Bombyx Batryticatus (parched), radix scutellariae, Snakegourd Fruit, fritillaria thunbergii, The root bark of Chinese wolf-berry, blackberry lily, cicada slough, Herba ephedrae, Radix Glycyrrhizae composition.
2. a kind of extract oral solution for poultry bronchial embolization as described in claim 1, which is characterized in that described Traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: sweet aster 6-12 parts;Sweet loguat leaf 6-12 parts;Radix scrophulariae 6-12 Part;Fry semen armeniacae amarae 3-9 parts;3-9 parts of prepared RHIZOMA PINELLIZE without adju-vant;3-9 parts of mulberry leaf;3-9 parts of the flower bud of lily magnolia;3-9 parts of Poria cocos;3-9 parts of Bombyx Batryticatus (parched);Radix scutellariae 3- 9 parts;3-9 parts of Snakegourd Fruit;3-9 parts of fritillaria thunbergii;3-9 parts of the root bark of Chinese wolf-berry;1-6 parts of blackberry lily;1-6 parts of cicada slough;1-5 parts of Herba ephedrae;Radix Glycyrrhizae 1-5 Part.
3. a kind of extract oral solution for poultry bronchial embolization as described in claim 1, it is characterised in that described Traditional Chinese medicine oral liquid is made of the Chinese medicine of following parts by weight: 10 parts of sweet aster, 9 parts of sweet loguat leaf, 9 parts of radix scrophulariae, fries bitter apricot 6 parts of benevolence, 6 parts of prepared RHIZOMA PINELLIZE without adju-vant, 6 parts of mulberry leaf, 6 parts of the flower bud of lily magnolia, 6 parts of Poria cocos, 6 parts of Bombyx Batryticatus (parched), 6 parts of radix scutellariae, 6 parts of Snakegourd Fruit, 6 parts of fritillaria thunbergii, 6 parts of the root bark of Chinese wolf-berry, 3 parts of blackberry lily, 3 parts of cicada slough, 3 parts of Herba ephedrae, 3 parts of Radix Glycyrrhizae.
4. a kind of preparation method of the extract oral solution for poultry bronchial embolization as described in claim 1, special Sign is: the prepared slices of Chinese crude drugs being mixed in proportion, for the first time plus 3-5 times of purified water, immersion 5 hours, heating are boiled and kept Slightly boiled 30 minutes, siphon supernatant, second plus 2-3 times of purified water heated and boil and kept for slightly boiled 30 minutes, siphon supernatant Liquid, the dregs of a decoction merge filtering and concentrating into specific gravity with 2 supernatants after squeezing be 1.15-1.35, and pH value controls in 5.0-7.0, adds pure Change water to full dose, 100ml/ bottles of oral administration solutions are made in packing, capping, labeling, packaging.
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Publication number Priority date Publication date Assignee Title
CN116832091A (en) * 2023-08-22 2023-10-03 河北征宇制药有限公司 Traditional Chinese medicine composition for treating poultry bronchial embolism, preparation and preparation method and application thereof

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CN103463346A (en) * 2013-09-23 2013-12-25 大连金鹏畜牧专业合作社 Medicine for treating chicken respiratory disease and preparation method thereof
CN108186957A (en) * 2018-02-26 2018-06-22 济南百鸣生物制药有限公司 A kind of Chinese medicine composition for treating poultry multi-pathogenesis respiratory disease and preparation method thereof

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CN101422582A (en) * 2007-11-02 2009-05-06 天津瑞普生物技术集团有限公司 Traditional Chinese medicine oral liquid for treating livestock and poultry respiratory infection
CN103463346A (en) * 2013-09-23 2013-12-25 大连金鹏畜牧专业合作社 Medicine for treating chicken respiratory disease and preparation method thereof
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116832091A (en) * 2023-08-22 2023-10-03 河北征宇制药有限公司 Traditional Chinese medicine composition for treating poultry bronchial embolism, preparation and preparation method and application thereof
CN116832091B (en) * 2023-08-22 2024-04-23 河北征宇制药有限公司 Traditional Chinese medicine composition for treating poultry bronchial embolism, preparation and preparation method and application thereof

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