CN102580003A - Chinese medicinal oral liquid for treating infantile asthma and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese medicinal oral liquid for treating infantile asthma and a preparation method thereof. A method for preparing the Chinese medicinal oral liquid comprises the following steps of: processing the following Chinese medicines: American ginseng, finger citron, mint, mulberry leaf, red paeony root, mongolian snakegourd root, turmeric root-tuber, pedate pinallia jackinthepulpit rhizome, thunberg fritillary bulb, loquat leaf, daturism, spiny jujube kernel and honey which have the effects of dispelling wind, moistening lung, resolving phlegm, relieving cough, soothing liver and tonifying qi, decocting, bottling, disinfecting and the like. By clinical experiments, the total effective rate is 96.7 percent, and particularly the improvement of symptoms and physical signs of asthmatic suffocating relieving, wheezing rale, lung rale, cough and the like of a treatment group is superior to that of symptoms and physical signs of asthmatic suffocating relieving, wheezing rale, lung rale, cough and the like of a control group obviously, and the Chinese medicinal oral liquid is convenient to take and is worthy of popularization and application.

Description

A kind of Chinese medicine oral liquid and method for preparing of treating infantile asthma

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine oral liquid and method for preparing of treating infantile asthma.

Background technology

Infantile asthma is the air flue chronic inflammatory disease of being participated in by multiple inflammatory cell such as EC, mastocyte and T lymphocyte; Make the susceptible person have airway hyperreactivity, cause the narrow thick wind property disease that increases with airway resistance of air flue popularity various motivating factors.The airway inflammation reaction and the airway hyper-reaction that continue are the characteristics of infantile asthma outbreak.In case asthma attack influences children's's normal growth, growth, life, study, the infant and the head of a family are agonized and anxiety.Asthma is the modal chronic inflammatory airway disease in the world today.Chinese children asthma total prevalence rate is that 0.9%～1.1%, 70%～80% childhood asthma was fallen ill before 5 years old, sends out a patient before 3 years old and accounts for 50% of childhood asthma.For the infantile asthma sickness rate is descended, the early intervention of medicine can make infantile asthma obtain to alleviate.Modern medicine adopts antiinflammatory and bronchodilator treatment more at present, and onset is slow, and the course of treatment is long, and side effect is big, and the patient is difficult for accepting.

Summary of the invention

It is better to the purpose of this invention is to provide a kind of curative effect, and child administration is treated the Chinese medicine oral liquid and the method for preparing of infantile asthma easily.

The objective of the invention is to realize through following technical scheme.The Chinese medicine oral liquid of this treatment infantile asthma is processed by following parts by weight of Chinese traditional medicine: Radix Panacis Quinquefolii 10-15 part, Fructus Citri Sarcodactylis 8-12 part, Herba Menthae 7-9 part, Folium Mori 7-9 part, Radix Paeoniae Rubra 5-7 part, Radix Trichosanthis 5-7 part, Radix Curcumae 7-9 part, Rhizoma Arisaematis 9-13 part, Bulbus Fritillariae Thunbergii 8-12 part, Folium Eriobotryae 9-11 part, Flos Daturae 5-7 part, jujube nucleus 6-8 part, Mel 8-12 part.

Preferably, the Chinese medicine oral liquid of this treatment infantile asthma is processed by following parts by weight of Chinese traditional medicine: 13 parts of Radix Panacis Quinquefoliis, 10 parts of Fructus Citri Sarcodactylis, 8 parts of Herba Menthaes, 8 parts on Folium Mori, 6 parts of Radix Paeoniae Rubra, 6 parts of Radix Trichosanthis, 8 parts of Radix Curcumaes, 11 parts of Rhizoma Arisaematiss, 10 parts of Bulbus Fritillariae Thunbergiis, 10 parts of Folium Eriobotryaes, 6 parts of Flos Daturae, 7 parts of jujube nucleus, 10 parts of Mel.

The step of above-mentioned Chinese medicine being processed oral liquid is following:

(1) concocts: get Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii earlier and steam five solarizations through five, be about to Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii is cleaned, and be cut into sheet, put into the food steamer back of boiling and steamed 50 minutes, take out sun cured, steam again, so steam and shine five times, be placed in the porcelain then and smash to pieces;

(2) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 30 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 30 minutes, and medicinal liquid is leached;

(3) bottling: with sealing in the bottle of packing into behind twice filtrating mixing;

(4) sterilization: the medicinal liquid bottle was put into the pressure cooker antibacterial 20 minutes, promptly get oral liquid of the present invention.

The pharmacological function of each Chinese medicine:

Sweet, the little hardship of Radix Panacis Quinquefolii; GUIXIN, lung, kidney channel.Boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.Fructus Citri Sarcodactylis is hot, bitter, temperature, nontoxic; Go into liver, spleen, stomach three through activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating are arranged.The Herba Menthae acrid in the mouth, cool in nature; Dispelling wind and heat pathogens, the clear sharp head, throat is regulated the flow of vital energy.The Folium Mori sweet in the mouth, hardship; Return lung, Liver Channel.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.Radix Paeoniae Rubra is bitter, is slightly cold; Return Liver Channel; The clots absorbing pain relieving, the removing heat from blood detumescence.Sweet, the little hardship of Radix Trichosanthis; Attach to the lung and stomach meridians; Clearing away heat and promoting production of body fluid, lung heat clearing wets one's whistle, detumescence and apocenosis.Radix Curcumae is hot, bitter; Return liver, the heart, lung meridian; Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Rhizoma Arisaematis is bitter, hot, temperature; Return lung, liver, spleen channel; Drying dampness to eliminate phlegm is expellingged wind and relieving convulsion, mass dissipating and swelling eliminating.The Bulbus Fritillariae Thunbergii removing heat-phlegm, powder detoxifcation.Folium Eriobotryae is bitter, is slightly cold, and returns lung, the stomach warp; Clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Flos Daturae returns liver, spleen channel; Relieving asthma, dispel the wind, pain relieving.

Jujube nucleus sweet in the mouth, acid, property is flat; Nourish conscience, the arresting sweating of calming the nerves.The invigorating middle warmer of Mel QI invigorating, analgesic antidotal and hundred medicines.

Clinical data

1, physical data

Whole 120 examples all come self-institute to be in hospital and the out-patient year November in March, 2008 to 2009, are divided into 2 groups at random.60 examples are organized in treatment, male 32 examples, women 28 examples; 1～11 years old age, average 5.6 years old; The course of disease 1～5.5 month, average 3.5 months.Matched group 60 examples, male 31 examples, women 29 examples; 1～11.5 years old age, average 5.5 years old; The course of disease 1～6 month, average 3.4 months.2 groups of case physical data comparing difference not statistically significants (P＞0.05) have comparability.

2, diagnostic criteria

The childhood asthma of preventing and treating the cooperative groups revision by national pediatric asthma in 1998 is prevented and treated in the routine childhood asthma diagnostic criteria and is diagnosed.

3, Therapeutic Method

The treatment group is taken oral liquid of the present invention, and 1～3 years old 5mL/ time, 3～7 years old 10mL/ time, 7～12 years old 15mL/ time, every day 3 times.Matched group is taken cough-stopping granule (Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin), and 1～3 years old 5mL/ time, 3～7 years old 10mL/ time, 7～12 years old 15mL/ time, every day 3 times.

2 groups equal 7 days be a course of treatment, judge curative effect after two courses of treatment.

4, curative effect determinate standard

Produce effects: breathe heavily and suppress alleviation, pulmonary rale disappears, disappearance of cough or obviously alleviate.Effectively: breathe heavily to suppress and alleviate, pulmonary rale reduces, and cough alleviates.Invalid: pulmonary rale is more, and cough does not alleviate.

5, therapeutic outcome

There are significance difference differnce table 1 in (1) two group of symptom, sign disappearance required time, and the treatment group obviously is superior to matched group (P＜0.01).

Table 1 liang group infant symptom, sign extinction time (x ± s, d)

(2) two groups of therapeutic outcomes are relatively seen table 2, and the treatment group obviously is superior to matched group (P＜0.01).

Table 2 liang group therapeutic outcome is { example (%) } relatively

The specific embodiment

Embodiment one: get Radix Panacis Quinquefolii 130g, Fructus Citri Sarcodactylis 100g, Herba Menthae 80g, Folium Mori 80g, Radix Paeoniae Rubra 60g, Radix Trichosanthis 60g, Radix Curcumae 80g, Rhizoma Arisaematis 110g, Bulbus Fritillariae Thunbergii 100g, Folium Eriobotryae 100g, Flos Daturae 60g, jujube nucleus 70g, Mel 100g, the step of processing oral liquid is following:

(5) concoct: get Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii earlier and steam five solarizations through five, be about to Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii is cleaned, and be cut into sheet, put into the food steamer back of boiling and steamed 50 minutes, take out sun cured, steam again, so steam and shine five times, be placed in the porcelain then and smash to pieces;

(6) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 30 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 30 minutes, and medicinal liquid is leached;

(7) bottling: with sealing in the bottle of packing into behind twice filtrating mixing;

(8) sterilization: the medicinal liquid bottle was put into the pressure cooker antibacterial 20 minutes, promptly get oral liquid of the present invention.

Embodiment two: get Radix Panacis Quinquefolii 100g, Fructus Citri Sarcodactylis 120g, Herba Menthae 70g, Folium Mori 90g, Radix Paeoniae Rubra 50g, Radix Trichosanthis 70g, Radix Curcumae 70g, Rhizoma Arisaematis 130g, Bulbus Fritillariae Thunbergii 80g, Folium Eriobotryae 90g, Flos Daturae 50g, jujube nucleus 80g, Mel 80g, the method for processing oral liquid is with embodiment one.

Embodiment three: get Radix Panacis Quinquefolii 150g, Fructus Citri Sarcodactylis 80g, Herba Menthae 90g, Folium Mori 70g, Radix Paeoniae Rubra 70g, Radix Trichosanthis 50g, Radix Curcumae 90g, Rhizoma Arisaematis 90g, Bulbus Fritillariae Thunbergii 120g, Folium Eriobotryae 110g, Flos Daturae 70g, jujube nucleus 60g, Mel 120g, the method for processing oral liquid is with embodiment one.

Claims (1)

1. Chinese medicine oral liquid of treating infantile asthma; The Chinese medicine oral liquid that it is characterized in that this treatment infantile asthma is processed by following parts by weight of Chinese traditional medicine: 13 parts of Radix Panacis Quinquefoliis, 10 parts of Fructus Citri Sarcodactylis, 8 parts of Herba Menthaes, 8 parts on Folium Mori, 6 parts of Radix Paeoniae Rubra, 6 parts of Radix Trichosanthis, 8 parts of Radix Curcumaes, 11 parts of Rhizoma Arisaematiss, 10 parts of Bulbus Fritillariae Thunbergiis, 10 parts of Folium Eriobotryaes, 6 parts of Flos Daturae, 7 parts of jujube nucleus, 10 parts of Mel, and the step of above-mentioned Chinese medicine being processed oral liquid is following:

(1) concocts: get Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii earlier and steam five solarizations through five, be about to Radix Panacis Quinquefolii, Bulbus Fritillariae Thunbergii is cleaned, and be cut into sheet, put into the food steamer back of boiling and steamed 50 minutes, take out sun cured, steam again, so steam and shine five times, be placed in the porcelain then and smash to pieces;

(2) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 30 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 30 minutes, and medicinal liquid is leached;

(3) bottling: with sealing in the bottle of packing into behind twice filtrating mixing;

(4) sterilization: the medicinal liquid bottle was put into the pressure cooker antibacterial 20 minutes, promptly get oral liquid of the present invention.