CN104056100B - A kind of Chinese medicine composition for treating infantile asthma - Google Patents
A kind of Chinese medicine composition for treating infantile asthma Download PDFInfo
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- CN104056100B CN104056100B CN201410290054.6A CN201410290054A CN104056100B CN 104056100 B CN104056100 B CN 104056100B CN 201410290054 A CN201410290054 A CN 201410290054A CN 104056100 B CN104056100 B CN 104056100B
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Abstract
The invention discloses a kind of Chinese medicine composition for treating infantile asthma, the Chinese medicine composition is prepared from by traditional Chinese medicinal material raw materials and pharmaceutically acceptable auxiliaries, by weight, described Chinese crude drug includes 30 42 parts of Rhizoma Fagopyri Dibotryiss, 15 26 parts of Folium Mori, 21 30 parts of Folium Bambusae, 21 30 parts of Folium Nelumbinis, 58 parts of Fructus Schisandrae Chinensis, 6 12 parts of Semen Raphani.Chinese medicine composition involved in the present invention verifies which is evident in efficacy by clinic application, reliable effect, mild in medicine property and, there are not toxic and side effects, after 12 course for the treatment of of medication, Asthma symptom complete incidence graph is not coughed and is not breathed heavily, and auscultation of lung is without exception.
Description
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of Chinese medicine composition for treating infantile asthma.
Background technology
The commonly encountered diseases and frequently-occurring disease of childhood period that infantile asthma is, are by eosinophilic granulocyte, mastocyte and T lymphocytes
The chronic ill reactive disorder of the air flue that participates in Deng inflammation cell and cytokine.And bronchial asthma regardless of season when
Can occur, especially in season in severe winter, and climate temperature fall ill when drastically changing more.Mostly because of physical weakness, or touch following
Factor induces primary disease by having the infant of latent phlegm to lung：Meet sense wind and cold.Direct stimulation is depressed, or environment cataclysm, inhale people's dust with
And diet etc..As development in children is not yet ripe, premunition is low, belongs to the body of immature yin and yang, and its internal organs is tender and lovely, and shape gas does not fill,
How empty lung spleen is, and easily empty easily real, phlegm stagnancy with the passing of time being easy to heat, mostly is intermingling cold and heat, deficiency and excess in clinical manifestation and deposits.Children's internal organs
Development also immaturity.Belong to lung due to human body skin to be responsible for, lungs are tender and lovely, skin defends that outer function is poor, and skin space between skin and muscles is not fine and close, wind
Cold, wind heat invades human body by fur or mouth and nose, and kidney deficiency, spleen, lung, three dirty functional disorder of kidney cause phlegm retention to be formed, pathogen take advantage of a weak point in opponent's defence and
Enter, pathogen enters lung meridian priming latent phlegm, phlegm rising following QI, obstruction of QI due to retention of phlegm are fought mutually sharp, and obstructing airway, ascending or descending movement of vital Qi are unfavorable, so that exhaling
The many suctions for going out are lacked, breath dyspnea with rapid and short breath, throat croup expectorant toot.Symptom is：Rapid breathing, suddenly, uncomfortable in chest rough, larynx has been asked for outbreak
Wheezing sound, must not pant prostration.Typically show effect in paroxysmal, or agitation, perspiration, expectoration, livid purple, pale complexion, weight occur then
The symptoms such as obnubilation.
Treatment to asthma is sucked via treatment of the airway smooth muscle spasm steering to airway inflammation is alleviated with hormone
Based on treatment, but hormone therapy has certain side effect, can cause the adverse consequencess such as upgrowth and development of children obstacle.Through inventor
Long-term practice show that Chinese medicine is controlled infantile asthma and there is preferably effect, obtains good effect.
Content of the invention
It is an object of the invention to by being furtherd investigate to folk remedy and being explored, treating children so as to provide one kind
The Chinese medicine composition of asthma.
The object of the present invention is achieved like this：
A kind of Chinese medicine composition for treating infantile asthma, is prepared from by traditional Chinese medicinal material raw materials and pharmaceutically acceptable auxiliaries, by weight
Part meter, described Chinese crude drug include：Rhizoma Fagopyri Dibotryiss 30-42 parts, Folium Mori 15-26 parts, Folium Bambusae 21-30 parts, Folium Nelumbinis 21-30 parts, the five tastes
Sub- 5-8 parts, Semen Raphani 6-12 parts.
Preferably, the Chinese medicine composition of infantile asthma is treated as mentioned above, and wherein by weight, described Chinese crude drug is former
Material is by Rhizoma Fagopyri Dibotryiss 34-37 parts, Folium Mori 18-22 parts, Folium Bambusae 24-26 parts, Folium Nelumbinis 24-26 parts, Fructus Schisandrae Chinensis 6-7 parts and Semen Raphani 8-10
Part composition.
In a most preferred embodiment of the present invention, the Chinese medicine composition of infantile asthma is treated as mentioned above, wherein
By weight, described traditional Chinese medicinal material raw materials are by 35 parts of Rhizoma Fagopyri Dibotryiss, 20 parts of Folium Mori, 25 parts of Folium Bambusae, 25 parts of Folium Nelumbinis, 6 parts of Fructus Schisandrae Chinensis
With 9 parts of compositions of Semen Raphani.
It should be noted that traditional Chinese medicinal material raw materials of the present invention have following source：Rhizoma Fagopyri Dibotryiss select polygonaceae plant
The dry rhizome of Rhizoma Fagopyri Dibotryiss Fagopyrum dibotrys (D.Don) Hara.Folium Mori select moraceae plants mulberry Morus alba L.
Dried leaves.Dried leaves of the Folium Bambusae from grass henon bamboo.Folium Nelumbinis select nymphaeaceae plant lotus Nelumbo
NuciferaGaertn. dried leaves.Fructus Schisandrae Chinensis select Magnoliacea plant schisandra chinensis Schisandra sphenanthera
The dry mature fruit of Rehd.et Wils..Semen Raphani is from the dry of crucifer Radix Raphani Raphanus sativus L.
Dry mature seed.
It is further preferred that the Chinese medicine composition of the treatment infantile asthma, wherein described Chinese medicine composition is oral
Preparation；Described oral formulations include oral liquid, tablet, granule, capsule etc..
Chinese medicine composition involved in the present invention verifies which is evident in efficacy by clinic application, reliable effect, mild in medicine property and, not
There are toxic and side effects, after the medication 1-2 courses for the treatment of, Asthma symptom complete incidence graph is not coughed and do not breathed heavily, and auscultation of lung is without exception.In addition,
The component of the medicine adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, low cost, therefore low production cost, patient
Spend less, with preferable economic benefit.
Specific embodiment
The specific embodiment of the present invention is the following is, technical scheme is done and is further described, but of the invention
Protection domain be not limited to these embodiments.
Embodiment 1：The preparation of Chinese medicine oral liquid
Weigh Rhizoma Fagopyri Dibotryiss 0.35kg, Folium Mori 0.20kg, Folium Bambusae 0.25kg, Folium Nelumbinis 0.25kg, Fructus Schisandrae Chinensis 0.06kg, Semen Raphani
0.09kg, cleans roguing, adds water and cover powder 2cm, soaks 1-1.2h, pulls medical material out and puts and add water to cook in multi-function extraction tank two
Secondary, the water of 8 times of amounts of totalling medical material, decoct 2h, take decocting liquid for the first time, filter, the water of second totalling 6 times of amount of medical material, decoct 1h,
Take decocting liquid twice to merge, filtration, when being concentrated into 90 DEG C, relative density is 1.10 concentrated solution；Concentrated solution is set to 0-5 DEG C of low temperature colds
24h is hidden, the filter aid diatomite for adding 0.3% by cold preservation liquid, filtration, filtrate are further concentrated to per milliliter of crude drug amount containing 3.0g, then plus
Enter appropriate cane sugar powder and 0.2% potassium sorbate, stir, set to 0 a DEG C deepfreeze 24h, cold preservation liquid is filtered, is obtained orally
Liquid.
Embodiment 2：The preparation of Chinese medicine granules
Weigh Rhizoma Fagopyri Dibotryiss 0.30kg, Folium Mori 0.18kg, Folium Bambusae 0.21kg, Folium Nelumbinis 0.30kg, Fructus Schisandrae Chinensis 0.08kg, Semen Raphani
0.12kg, cleans roguing, adds water and cover powder 2cm, soaks 1-1.2h, pulls medical material out and puts and add water to cook in multi-function extraction tank two
Secondary, the water of 8 times of amounts of totalling medical material, decoct 2h, take decocting liquid for the first time, filter, the water of second totalling 6 times of amount of medical material, decoct 1h,
Take decocting liquid twice to merge, filtration, filtrate concentrating under reduced pressure under the conditions of 0.08MPa, 65 DEG C into relative density when 65 DEG C is
The extractum of 1.15g/mL, extractum are put in stainless steel disc, and vacuum drying (less than 60 DEG C) is crushed into dry cream, plus cane sugar powder, makes 40
Mesh granule powder is simultaneously packed, and often wraps 20g.
Embodiment 3：The preparation of Chinese medicine granules
Weigh Rhizoma Fagopyri Dibotryiss 0.42kg, Folium Mori 0.25kg, Folium Bambusae 0.25kg, Folium Nelumbinis 0.25kg, Fructus Schisandrae Chinensis 0.08kg, Semen Raphani
0.08kg, cleans roguing, adds water and cover powder 2cm, soaks 1-1.2h, pulls medical material out and puts and add water to cook in multi-function extraction tank two
Secondary, the water of 8 times of amounts of totalling medical material, decoct 2h, take decocting liquid for the first time, filter, the water of second totalling 6 times of amount of medical material, decoct 1h,
Take decocting liquid twice to merge, filtration, filtrate concentrating under reduced pressure under the conditions of 0.08MPa, 65 DEG C into relative density when 65 DEG C is
The extractum of 1.15g/mL, extractum are put in stainless steel disc, and vacuum drying (less than 60 DEG C) is crushed into dry cream, plus cane sugar powder, makes 40
Mesh granule powder is simultaneously packed, and often wraps 20g.
Clinical practice example：Effectiveness study of the Chinese medicinal formulae to infantile asthma
Through the children with bronchial asthma disease 54 of clinical definite, to cough, between tachypnea, larynx, wheezing is obvious for clinical manifestation, or even breathing is tired
Difficulty, double fullness of the lung cloth wheezing sounds are characterized.In all cases, male 31, women 23；4～13 years old age, mean age 8.9
± 2.0 years old；The course of disease 3～18 days.54 infants are randomly divided into Chinese medicine group and matched group is each 27, two groups in sex, age, disease
The aspects such as journey, the state of an illness without significant difference, with comparability.
Chinese medicine group gives Chinese medicine decoction, prescription：Rhizoma Fagopyri Dibotryiss 35g, Folium Mori 20g, Folium Bambusae 25g, Folium Nelumbinis 25g, Fructus Schisandrae Chinensis 6g, Lay
Fu 9g.Plus 2L decocting in water is opened rear slow fire and boiled medicine 1.5h, then concentrated medicament is to 100ml.4～7 years old each 20ml, more than 7 years old every
Secondary 30ml.3 times a day, decoction being taken warmly after sugaring in 30 minutes before meals.Matched group using conventional relieving cough and resolving phlegm, relieving asthma, anti-infective therapy.
Two groups are treated 10 days for 1 course for the treatment of, are treated 1～2 course for the treatment of altogether, are observed curative effect.The criterion of clinical efficacy is as follows：
Cure：After the medication 1-2 courses for the treatment of, infant symptom complete incidence graph is not coughed and is not breathed heavily, and auscultation of lung is without exception；
Effective：Symptom SPR, does not breathe heavily, and occasionally has cough with asthma during climate change, continues medication and alleviates quickly again；
Invalid：After 2 courses for the treatment of of medication, the state of an illness is without improvement.
Therapeutic outcome is shown in Table 1.It is effective 28 that curative effect statistical result according to table 1 can be seen that test group healing
(90.32%), total effective rate is 96.77%；And matched group cures effective 9 (29.03%), total effective rate is 67.74%.Aobvious
So, test group is substantially better than matched group.
1 two groups of comparitive studies (example) of table
Claims (4)
1. a kind of Chinese medicine composition for treating infantile asthma, it is characterised in that：By traditional Chinese medicinal material raw materials and pharmaceutically acceptable auxiliaries preparation
Into by weight, described traditional Chinese medicinal material raw materials are by Rhizoma Fagopyri Dibotryiss 34-37 parts, Folium Mori 18-22 parts, Folium Bambusae 24-26 parts, Folium Nelumbinis 24-
26 parts, Fructus Schisandrae Chinensis 6-7 parts and Semen Raphani 8-10 parts composition.
2. the Chinese medicine composition of infantile asthma is treated according to claim 1, it is characterised in that：By weight, described
Traditional Chinese medicinal material raw materials are made up of 9 parts of 35 parts of Rhizoma Fagopyri Dibotryiss, 20 parts of Folium Mori, 25 parts of Folium Bambusae, 25 parts of Folium Nelumbinis, 6 parts of Fructus Schisandrae Chinensis and Semen Raphani.
3. according to claim 1 or claim 2 treatment infantile asthma Chinese medicine composition, it is characterised in that：Described Chinese medicine composition
Thing is oral formulations.
4. the Chinese medicine composition of infantile asthma is treated according to claim 3, it is characterised in that：Described oral formulations include
Oral liquid, tablet, granule, capsule.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102580003A (en) * | 2012-03-14 | 2012-07-18 | 赵莹 | Chinese medicinal oral liquid for treating infantile asthma and preparation method thereof |
| CN102988832A (en) * | 2012-12-03 | 2013-03-27 | 刘瑞青 | Traditional Chinese medicine composition used for treating asthma of children |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100496601C (en) * | 2006-03-16 | 2009-06-10 | 李玉海 | Chinese medicine mixture for treating infantile cough |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102580003A (en) * | 2012-03-14 | 2012-07-18 | 赵莹 | Chinese medicinal oral liquid for treating infantile asthma and preparation method thereof |
| CN102988832A (en) * | 2012-12-03 | 2013-03-27 | 刘瑞青 | Traditional Chinese medicine composition used for treating asthma of children |
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