CN102284023A - Chinese medicinal composition for treating asthma - Google Patents
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Abstract
本发明涉及一种治疗喘症的中药组合物,是由下列重量份的中药原料组成:炙麻黄5~20份、桂枝5~20份、冬花5~25份、紫苑花5~25份、半夏5~20份、桑白皮5~25份、苏子5~25份、黄芩5~25份、杏仁5~20份、淡豆豉5~20份、五味子5~20份、陈皮5~25份、枳壳5~20份、瓜蒌5~20份、茯苓5~25份、栀子5~25份、金银花5~30份、芦根10~40份、莱菔子5~20份、射干5~20份、地骨皮5~25份、知母2~15份、青天葵5~20份。本发明具有清热解表、润燥祛痰、宣肺平喘、理气健脾、益气补肾之功效,治疗喘症疗效可靠。该组合物配制简便、药源广、成本低,其组分药性平和、无副作用。The invention relates to a traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in parts by weight: 5-20 parts of roasted ephedra, 5-20 parts of cassia twig, 5-25 parts of winter flower, and 5-25 parts of aster flower , pinellia 5-20 parts, mulberry root 5-25 parts, perilla 5-25 parts, scutellaria baicalensis 5-25 parts, almonds 5-20 parts, light tempeh 5-20 parts, schisandra 5-20 parts, tangerine peel 5 parts ~25 parts, 5~20 parts of Citrus aurantium, 5~20 parts of Melon, 5~25 parts of Poria cocos, 5~25 parts of gardenia, 5~30 parts of honeysuckle, 10~40 parts of reed root, 5~20 parts of radish , 5-20 parts of Shegan, 5-25 parts of Digupi, 2-15 parts of Anemarrhena, and 5-20 parts of Qingtiankui. The invention has the effects of clearing away heat and relieving exterior syndrome, moistening dryness and eliminating phlegm, clearing lung and relieving asthma, regulating qi and invigorating spleen, replenishing qi and tonifying kidney, and has reliable curative effect on treating asthma. The composition has the advantages of simple preparation, wide drug sources and low cost, and its components have mild medicinal properties and no side effects.
Description
the
技术领域 technical field
本发明涉及一种传统草药的未确定结构的医药配制品,尤其是一种治疗喘症的中药组合物。 The invention relates to a pharmaceutical preparation of undetermined structure of traditional herbal medicine, especially a traditional Chinese medicine composition for treating asthma.
背景技术 Background technique
喘证,一般通称气喘,是以呼吸急促为特征的一种病症,以呼吸急促,甚至张口耸肩,鼻翼煽动为主要特征。常为某些急性疾病的主要症状,若喘促严重,持续不解,可发生虚脱。目前,临床上治疗喘证的方法主要是采用药物抑制缓解气喘发作为主。例如,使用支气管扩张剂及止咳剂、化痰剂等药。这种治疗方法存在着治标不治本的不足。 Asthma syndrome, generally known as asthma, is a disease characterized by shortness of breath, with shortness of breath, even shrugging of the mouth, and flaring of the nose. It is often the main symptom of some acute diseases. If shortness of breath is severe and persistent, collapse may occur. At present, the clinical method for treating asthma is mainly to use drugs to suppress and relieve asthma attacks. For example, use bronchodilators, cough suppressants, expectorants and other medicines. This method of treatment exists the deficiency that treats the symptoms but not the disease.
中医认为:喘症的病因甚多,六淫外感、七情所伤、水饮潴留、痰热内蕴、病后虚弱以及饮食劳倦都可以引起哮喘症,而喘症发生的根本原因又在于人体肺、脾、肾等脏的功能失调,导致肺主气,肾纳气的功能失常,气的升降出入障碍,导致喘症发作。喘症的病因病机如下: 喘症有虚实之异。虚者为正气虚:由于肺主气,肾主纳气,故又以肺肾二脏之虚为主。实者为邪气实:外来之邪不外风寒燥热,内生之邪主要室痰浊或水饮。 Traditional Chinese medicine believes that there are many causes of asthma. Exogenous factors caused by the six exogenous factors, injury by the seven emotions, water retention, phlegm-heat accumulation, weakness after illness, and fatigue from eating can all cause asthma, and the root cause of asthma lies in the human body. Dysfunction of the lungs, spleen, kidneys and other viscera leads to the dysfunction of the lungs governing qi, the dysfunction of the kidneys in receiving qi, and the obstruction of the ascending and exiting of qi, resulting in the onset of asthma. The etiology and pathogenesis of asthma are as follows: Asthma has the difference of deficiency and excess. Those who are deficient are deficient in righteousness: since the lungs govern qi and the kidneys govern the intake of qi, the deficiency of the lungs and kidneys is the main one. Excessiveness is the excess of evil qi: external evils are nothing but wind, cold, dryness and heat, and endogenous evils are mainly turbid phlegm in the room or drinking water.
根据中医理论,针对喘症的发病机理,进行辩证配伍组方,以达到标本兼治的目的。 According to the theory of traditional Chinese medicine, according to the pathogenesis of asthma, dialectical compatibility prescriptions are carried out to achieve the purpose of treating both symptoms and root causes.
发明内容 Contents of the invention
为了克服现有技术中西药对喘症治标不治本的不足,本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗喘症的中药组合物。 In order to overcome the shortcomings of traditional Chinese and Western medicines in the prior art for treating asthma symptoms but not the root cause, the invention provides a traditional Chinese medicine composition for treating asthma with simple preparation, low cost, significant curative effect and no side effects.
本发明解决其技术问题所采用的技术方案是:一种治疗喘症的中药组合物,其特征在于:其是由下列重量份的中药原料组成:炙麻黄5~20份、桂枝5~20份、冬花5~25份、紫苑花5~25份、半夏5~20份、桑白皮5~25份、苏子5~25份、黄芩5~25份、杏仁5~20份、淡豆豉5~20份、五味子5~20份、陈皮5~25份、枳壳5~20份、瓜蒌5~20份、茯苓5~25份、栀子5~25份、金银花5~30份、芦根10~40份、莱菔子5~20份、射干5~20份、地骨皮5~25份、知母2~15份、青天葵5~20份。 The technical solution adopted by the present invention to solve the technical problem is: a traditional Chinese medicine composition for treating asthma, characterized in that it is composed of the following traditional Chinese medicine raw materials in parts by weight: 5-20 parts of roasted ephedra, 5-20 parts of cassia twig 5-25 parts of winter flowers, 5-25 parts of asters, 5-20 parts of pinellia, 5-25 parts of Morus alba, 5-25 parts of perilla, 5-25 parts of skullcap, 5-20 parts of almonds, 5-20 parts of light tempeh, 5-20 parts of schisandra, 5-25 parts of tangerine peel, 5-20 parts of Fructus aurantium, 5-20 parts of Trichosanthes, 5-25 parts of Poria cocos, 5-25 parts of gardenia, 5-30 parts of honeysuckle 10-40 parts of reed root, 5-20 parts of radish seed, 5-20 parts of shegan, 5-25 parts of Digupi, 2-15 parts of Anemarrhena, and 5-20 parts of Qingtiankui.
本发明的优选技术方案是:一种治疗喘症的中药组合物,其特征在于:其是由下列重量份的中药原料组成:炙麻黄10份、桂枝10份、冬花15份、紫苑花15份、半夏10份、桑白皮15份、苏子12份、黄芩15份、杏仁10份、淡豆豉8份、五味子8份、陈皮15份、枳壳10份、瓜蒌10份、茯苓15份、栀子12份、金银花20份、芦根30份、莱菔子10份、射干8份、地骨皮12份、知母6份、青天葵10份。 The preferred technical scheme of the present invention is: a traditional Chinese medicine composition for treating asthma, characterized in that: it is composed of the following Chinese medicinal raw materials in parts by weight: 10 parts of Sun-roasted Ephedra, 10 parts of Guizhi, 15 parts of Winter Flower, Aster Flower 15 parts, Pinellia 10 parts, Morus alba 15 parts, Perilla 12 parts, Scutellaria baicalensis 15 parts, Almond 10 parts, Light tempeh 8 parts, Schisandra chinensis 8 parts, Tangerine peel 15 parts, Citrus aurantium 10 parts, Trichosanthes 10 parts, 15 parts of Poria cocos, 12 parts of gardenia, 20 parts of honeysuckle, 30 parts of reed root, 10 parts of radish seed, 8 parts of shegan, 12 parts of Digupi, 6 parts of Anemarrhena, and 10 parts of Qingtiankui.
本发明中药组合物是在传统中医理论和临床经验指导下,以清热解表、润燥祛痰、宣肺平喘、理气健脾、益气补肾为治则,精选药物组方,标本兼治。本发明中药组合物中:炙麻黄、桂枝、淡豆豉发汗散寒、温经通脉、宣肺平喘;冬花、紫苑花润肺下气、止咳化痰;半夏、黄芩燥湿化痰、泻火解毒、消痞散结;桑白皮、苏子泻肺平喘、降气消痰;杏仁、陈皮、枳壳、瓜蒌祛痰止咳、平喘润肠、理气健脾;五味子收敛固涩、益气补肾;茯苓渗湿利水、健脾和胃;栀子、金银花宣散泻火、清热利湿、凉血解毒;射干、知母、芦根清热解毒,生津利尿、润燥消痰;地骨皮凉血除蒸、清肺降火;莱菔子、青天葵降气化痰、清肺止咳,健脾消积。本发明精选药物组方,其药物组分经辩证配伍,在作用上相辅相成,具有协同作用,其药效优于单味药物的效果,能够以达到标本兼的目的。本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。 Under the guidance of traditional Chinese medicine theory and clinical experience, the traditional Chinese medicine composition of the present invention is based on the principles of clearing heat and relieving exterior, moistening dryness and eliminating phlegm, clearing lung and relieving asthma, regulating qi and invigorating spleen, nourishing qi and invigorating kidney, and selects the prescription of medicine to treat both symptoms and root causes. . In the traditional Chinese medicine composition of the present invention: roasted ephedra, cassia twig, and light tempeh sweat and dispel cold, warm the meridians and unblock the meridian, relieve lung and relieve asthma; Purging fire and detoxification, dispelling lumps and dispelling stagnation; Morus alba, Suzi purging lungs and relieving asthma, lowering Qi and eliminating phlegm; Astringent, replenishing qi and invigorating the kidney; Poria cocos oozes dampness and diuresis, invigorates the spleen and stomach; Gardenia, honeysuckle disperses fire, clears heat and dampness, cools blood and detoxifies; Shegan, Anemarrhena, reed root clears heat and detoxifies, promotes body fluid and diuresis, moistens dryness and eliminates phlegm Digupi cools blood and removes steam, clears lungs and reduces fire; radish seed, blue sky sunflower reduces qi and reduces phlegm, clears lungs and relieves cough, invigorates the spleen and eliminates accumulation. The selected medicine prescription of the present invention, its medicine component is through dialectical compatibility, complements each other in action, has synergistic effect, and its medicine effect is better than the effect of single herb medicine, can achieve the purpose of both specimen and essential medicine. The components of the composition of the invention all adopt natural traditional Chinese medicine raw materials, and the preparation is simple, the medicine source is wide, and the cost is low.
本发明遵循中医的处方用药原则,各种药物组分采用水煎服用。经临床应用验证,其疗效显著可靠,药性平和,未出现毒副作用,有效率达95%,治愈率65%。 The invention follows the principle of prescription medication in traditional Chinese medicine, and various medicinal components are taken by decoction. It has been verified by clinical application that its curative effect is remarkable and reliable, its properties are mild, and there are no toxic and side effects. The effective rate is 95%, and the cure rate is 65%.
具体实施方式 Detailed ways
下面结合实施例对本发明作进一步说明。 The present invention will be further described below in conjunction with embodiment.
实施例1 Example 1
一种治疗喘症的中药组合物,其是由下列重量配比的中药原料组成:炙麻黄10g、桂枝10g、冬花15g、紫苑花15g、半夏10g、桑白皮15g、苏子12g、黄芩15g、杏仁10g、淡豆豉8g、五味子8g、陈皮15g、枳壳10g、瓜蒌10g、茯苓15g、栀子12g、金银花20g、芦根30g、莱菔子10g、射干8g、地骨皮12g、知母6g、青天葵10g。 A traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 10g Sun-roasted Ephedra, 10g Guizhi, 15g Winter Flower, 15g Aster Flower, 10g Pinellia, 15g Morus alba, and 12g Perilla , Scutellaria baicalensis 15g, almond 10g, light tempeh 8g, schisandra 8g, tangerine peel 15g, citrus aurantium 10g, melon 10g, poria cocos 15g, gardenia 12g, honeysuckle 20g, reed root 30g, radish 10g, shegan 8g, digupi 12g , Anemarrhena 6g, Qingtiankui 10g.
实施例2 Example 2
一种治疗喘症的中药组合物,其是由下列重量配比的中药原料组成:炙麻黄15g、桂枝15g、冬花5g、紫苑花25g、半夏15g、桑白皮10g、苏子20g、黄芩5g、杏仁5g、淡豆豉15g、五味子10g、陈皮25g、枳壳5g、瓜蒌15g、茯苓20g、栀子5g、金银花30g、芦根40g、莱菔子15g、射干15g、地骨皮5g、知母10g、青天葵20g。 A traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 15g sun-burned ephedra, 15g cassia twig, 5g winter flower, 25g aster flower, 15g pinellia, 10g mulberry bark, and 20g perilla , Scutellaria baicalensis 5g, almond 5g, light tempeh 15g, schisandra 10g, tangerine peel 25g, citrus aurantium 5g, melon 15g, poria cocos 20g, gardenia 5g, honeysuckle 30g, reed root 40g, radish 15g, shegan 15g, digupi 5g , Anemarrhena 10g, Qingtiankui 20g.
实施例3 Example 3
一种治疗喘症的中药组合物,其是由下列重量配比的中药原料组成:炙麻黄5g、桂枝20g、冬花10g、紫苑花20g、半夏5g、桑白皮20g、苏子5g、黄芩20g、杏仁15g、淡豆豉20g、五味子5g、陈皮5g、枳壳15g、瓜蒌20g、茯苓5g、栀子20g、金银花25g、芦根10g、莱菔子5g、射干20g、地骨皮15g、知母2g、青天葵5g。 A traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 5g of Sun-roasted Ephedra, 20g of Guizhi, 10g of Winter Flower, 20g of Aster Flower, 5g of Banxia, 20g of Cortex Mori, 5g of Perilla , Scutellaria baicalensis 20g, almond 15g, tempeh 20g, schisandra 5g, tangerine peel 5g, citrus aurantium 15g, fennel 20g, poria cocos 5g, gardenia 20g, honeysuckle 25g, reed root 10g, radish seed 5g, shegan 20g, digupi 15g , Anemarrhena 2g, Qingtiankui 5g.
实施例4 Example 4
一种治疗喘症的中药组合物,其是由下列重量配比的中药原料组成:炙麻黄20g、桂枝5g、冬花20g、紫苑花10g、半夏20g、桑白皮5g、苏子25g、黄芩10g、杏仁20g、淡豆豉5g、五味子15g、陈皮10g、枳壳20g、瓜蒌5g、茯苓25g、栀子15g、金银花5g、芦根20g、莱菔子20g、射干5g、地骨皮10g、知母15g、青天葵5g。 A traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 20g Sun-roasted Ephedra, 5g Guizhi, 20g Winter Flower, 10g Aster Flower, 20g Pinellia Pinellia, 5g Cortex Mori, 25g Perilla , Scutellaria baicalensis 10g, almond 20g, light tempeh 5g, schisandra 15g, tangerine peel 10g, citrus aurantium 20g, fennel 5g, poria cocos 25g, gardenia 15g, honeysuckle 5g, reed root 20g, radish seed 20g, shegan 5g, digupi 10g , Anemarrhena 15g, Qingtiankui 5g.
实施例5 Example 5
一种治疗喘症的中药组合物,其是由下列重量配比的中药原料组成:炙麻黄12g、桂枝12g、冬花25g、紫苑花5g、半夏8g、桑白皮25g、苏子15g、黄芩25g、杏仁8g、淡豆豉10g、五味子20g、陈皮20g、枳壳8g、瓜蒌12g、茯苓10g、栀子25g、金银花15g、芦根25g、莱菔子12g、射干10g、地骨皮20g、知母8g、青天葵12g。 A traditional Chinese medicine composition for treating asthma, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 12g Sun-roasted Ephedra, 12g Guizhi, 25g Winter Flower, 5g Aster Flower, 8g Pinellia Pinellia, 25g Mori Cortex, 15g Perilla , Scutellaria baicalensis 25g, almond 8g, light tempeh 10g, schisandra 20g, tangerine peel 20g, citrus aurantium 8g, melon 12g, poria cocos 10g, gardenia 25g, honeysuckle 15g, reed root 25g, radish seed 12g, shegan 10g, digupi 20g , Anemarrhena 8g, Qingtiankui 12g.
本发明实施例中的中药组合物按常规的水煎法制取药剂,具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约5厘米,进行煎煮。未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二煎煮,水沸后煎煮15~20分钟。两次煎煮取汁,合并。 The traditional Chinese medicine composition in the embodiment of the present invention is prepared according to the conventional water decoction method. The specific method is as follows: put the Chinese medicine raw materials of the prescription into the container, add cold water to cover the medicine surface, soak for 15-20 minutes, and then add water to cover the medicine. The medicine noodles are about 5 cm, and they are decocted. Before boiling, use strong fire to decoct, and after boiling, use slow fire to decoct for 20-30 minutes; for the second decoction, decoct for 15-20 minutes after the water boils. Decoct twice to extract the juice and combine.
一种治疗喘症的中药组合物,临床疗效总结: A Chinese medicine composition for treating asthma, clinical curative effect summary:
一、一般性资料:本中药组合物应用于临床观察病例120例,其中男64例,女56例,其年龄15~70岁。 1. General information: This traditional Chinese medicine composition was applied to 120 cases of clinical observation, including 64 males and 56 females, aged 15-70 years.
二、用法用量:临床应用时,组合物中的组分根据患者的体重和年龄酌情增减。本中药组合物一日一剂,水煎两遍取汁约300ml,分早、晚两次服用。服药期间忌食辛辣、寒凉之物。 2. Usage and dosage: In clinical application, the components in the composition should be increased or decreased according to the patient's weight and age. One dose of this Chinese medicine composition a day, decoct in water twice to get about 300ml of juice, and take it twice in the morning and evening. Avoid spicy and cold food while taking the medicine.
三、疗效标准: 3. Efficacy standard:
(1)痊愈:症状和体征消失或基本消失; (1) Recovery: symptoms and signs disappear or basically disappear;
(2)显效:症状和体征大部分好转; (2) Significant effect: Most of the symptoms and signs improved;
(3)有效:症状和体征一部分好转; (3) Effective: part of the symptoms and signs improved;
(4)无效;症状和体征均无明显改善,症状如前。 (4) Ineffective; the symptoms and signs were not significantly improved, and the symptoms were as before.
四、治疗效果:该临床观察病例中,服药10-60天,痊愈78例,随访未见复发;显效20例,有效16例,无效6例。治疗期间未发生毒副作用。 4. Treatment effect: Among the clinical observation cases, 78 cases were cured after taking the medicine for 10-60 days, and no recurrence was found in the follow-up; 20 cases were markedly effective, 16 cases were effective, and 6 cases were ineffective. No toxic side effects occurred during the treatment.
五、典型病例: 5. Typical cases:
病例1: Case 1:
许某,男,48岁。有慢性支气管炎病史,每遇天气转寒则加重。前期不慎感寒,出现喘息气短,吸气困难,气不得续,动则更甚,伴咳声低弱,咳痰白滑量多,畏寒自汗,面白无华,神疲乏力,舌淡瘀暗,苔白滑,脉沉细。诊断为喘症。服用本发明中药组合物制备的药剂14天,喘息咳痰、畏风自汗诸症递减;继续服用药剂14天,喘平咳止,畏风自汗,诸症皆愈,无明显不适。半年后随访,喘咳未复发。 Xu, male, 48 years old. There is a history of chronic bronchitis, which is exacerbated whenever the weather turns cold. Inadvertently caught cold in the early stage, wheezing, shortness of breath, difficulty in breathing, breathlessness, worse when moving, accompanied by low and weak coughing, white and slippery sputum, aversion to cold and spontaneous sweating, pale complexion, fatigue, and pale tongue Dark stasis, white and slippery coating, deep and thready pulse. Diagnosed with asthma. After taking the medicament prepared by the traditional Chinese medicine composition of the present invention for 14 days, the symptoms of wheezing, expectoration, and wind-fearing spontaneous sweating gradually decreased; after continuing to take the medicament for 14 days, the symptoms of dyspnea, cough, and wind-fearing spontaneous sweating all healed without obvious discomfort. Follow up a case by regular visits to after half a year, dyspnea cough does not recur.
病例2: Case 2:
宋某,女,30岁。咳嗽、喘憋20余天。患者受凉后出现咳嗽、咯少量白粘痰,活动后喘憋明显,无发热、咯血、胸痛。服用本发明中药组合物制备的药剂6天,诸症好转,继续服用3天,痊愈。 Song, female, 30 years old. Coughing and wheezing for more than 20 days. The patient developed cough and coughed up a small amount of white and sticky sputum after being exposed to cold, and had obvious wheezing after activities, without fever, hemoptysis, or chest pain. Take the medicament prepared by the Chinese medicine composition of the present invention for 6 days, all diseases took a turn for the better, continue to take 3 days, fully recovered.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102688293A (en) * | 2012-06-14 | 2012-09-26 | 李良 | Poria traditional Chinese medicine decoction for treating asthma and preparation method thereof |
| CN105168991A (en) * | 2015-07-29 | 2015-12-23 | 陈忠田 | Traditional Chinese medicinal composition for treating chronic bronchitis |
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2011
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102688293A (en) * | 2012-06-14 | 2012-09-26 | 李良 | Poria traditional Chinese medicine decoction for treating asthma and preparation method thereof |
| CN105168991A (en) * | 2015-07-29 | 2015-12-23 | 陈忠田 | Traditional Chinese medicinal composition for treating chronic bronchitis |
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Application publication date: 20111221 |