CN1251732C - Chinese medicine for treating intrapulmonic infection and SARS - Google Patents

Chinese medicine for treating intrapulmonic infection and SARS Download PDF

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CN1251732C
CN1251732C CN 200310109919 CN200310109919A CN1251732C CN 1251732 C CN1251732 C CN 1251732C CN 200310109919 CN200310109919 CN 200310109919 CN 200310109919 A CN200310109919 A CN 200310109919A CN 1251732 C CN1251732 C CN 1251732C
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CN1608654A (en
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徐万富
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Abstract

The present invention relates to a medicine which can be used for treating infection in a lung by the traditional Chinese medicine and preventing and treating atypical pneumonia, which belongs to the technical field of the traditional Chinese medicine. The medicine is mainly composed of 1 to 5 shares of ephedra herb, 1 to 5 shares of almond, 3 to 30 shares of gypsum, 1 to 10 shares of liquorice, 1 to 10 shares of balloonflower root, 1 to 10 shares of baical skullcap root, 1 to 5 shares of coptis, 1 to 10 shares of phellodendron, 1 to 5 shares of indian buead, 1 to 3 shares of rhubarb, 1 to 5 shares of honeysuckle, 1 to 5 shares of forsythia suspensa, 1 to 5 shares of giant knotweed rhizome, 2 to 10 shares of radish seed, 1 to 5 shares of perilla fruit, 1 to 10 shares of pinellia, 1 to 10 shares of chrysanthemum, 1 to 10 shares of dandelion and 1 to 5 shares of green dragon. The present invention can be prepared into capsules, can also be prepared into oral liquor, is washed, aired, dried, pulverized, sieved, and respectively packed, or is washed, aired, decocted, boiled, combined with physic liquor, concentrated, added with distilled water to be diluted, bottled, sterilized, cooled and sealed. The present invention can effectively treat the infection in a lung, an effective rate can reach more than 90%, and atypical pneumonia can be prevented and treated.

Description

A kind of Chinese medicine for the treatment of intrapulmonary infection
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine that utilizes treatment by Chinese herbs intrapulmonary infection and prevention of atypical pneumonia.
Background technology
The year ends 2002, particularly wreaked havoc world part country in spring in 2003, especially the atypical pneumonia of Southeast Asia and China (SARS) is a kind of very strong communicable respiratory tract disease that has, cause respiratory tract and pulmonary infection after infected, and develop into more serious injury of lung and respiratory failure easily, in the people, cause bigger fear.But, be a member of a political party and government, particularly under the Hu Jintao General Secretary's great attention and numerous medical personnels' the effort, obtained effective containment, atypia sickness rate scorching and suspected case has reached zero in by the end of June, 2003 by.Can not become extinct as a kind of infectious disease, be again the season that respiratory tract disease is easily sent out autumn and winter quickly, and it also is potential that atypical pneumonia (SARS) is staged a comeback.Utilize the medicine of treatment by Chinese herbs intrapulmonary infection many, but all can not prevention of atypical pneumonia.
Summary of the invention
The purpose of this invention is to provide a kind of intrapulmonary infection of can treating again to the effective a kind of Chinese medicine for the treatment of intrapulmonary infection of prevention of atypical pneumonia.
MAXINGSHIGAN TANG is an ancient prescription, is the bronchitic prescription commonly used of treatment, and its epheday intermedia is principal agent, and bronchial smooth muscle is had spasmolysis thereby antitussive; Other has boosting, and heart is had excitation, also can excited cerebral cortex and respiratory center, infer that it has inhibitory action to virus, thereby influenza virus had inhibitory action, thus use be principal agent.Semen Armeniacae Amarum has the expelling phlegm for arresting cough antiasthmatic effect, and two medicines match and bring out the best in each other.Radix Glycyrrhizae can reduce pharyngeal stimulation, and its antitussive effect is except that pharyngeal and be central, and its intensity is similar to codeine.The proper eliminating phlegm and stopping cough of three medicine compatibilities is very obvious; The Gypsum Fibrosum refrigeration function is stronger, so ancient prescription is to control to cough to eliminate the phlegm and heating person is very suitable.
The present invention is basic improved prescription with ancient prescription.Add Radix Platycodonis to strengthen its phlegm-dispelling functions; Add Semen Raphani, Fructus Perillae, Semen Sinapis Albae and be that the therapeutic method to keep the adverse QI flowing downwards is relievingd asthma and can antiphlogistic antibacterial.Add Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) again, promptly relieving cough and expelling phlegm has the town to tell Detoxication again.The present invention all has effect preferably to cough, abundant expectoration, asthma, heating, inflammation.
The present invention adds Rhizoma Atractylodis, and to join Herba Ephedrae analgesic in order to diaphoresis, and its sterilization effect is also rather good, and adding Herba Taraxaci has stronger bactericidal action to various bacteria, and promptly heat-clearing and toxic substances removing has diuresis again; The inventor thinks that Herba Taraxaci has antivirus action, and this more helps the fight against SARS.Add again in the heat-clearing and toxic substances removing various bacteria is had inhibiting Flos Lonicerae, Fructus Forsythiae, Flos Chrysanthemi; Also have the existing antimicrobial effect of Radix Scutellariae, antiinflammatory, antiallergic action, diuresis, hypotensive effect are arranged again; Cortex Phellodendri, its effect of Rhizoma Coptidis are similar to Radix Scutellariae, and some effect more is better than Radix Scutellariae.In experiment, resisiting influenza virus, Newcastle virus all there is certain inhibitory action; Also have Rhizoma Polygoni Cuspidati that multiple virus is all had obvious inhibitory action, cooperate said medicine, antiviral can be stronger, has synergistic.Rhizoma Polygoni Cuspidati has unique therapeutic effect to pneumonia in addition.The present invention adds Poria promoting diuresis to eliminate damp pathogen, mind tranquilizing and the heart calming, adds the logical lung of Radix Et Rhizoma Rhei and rushes down following, relieving constipation detoxifcation, makes pyretic toxicity from eliminating convenient to both.Above-mentioned prescription has Herba Ephedrae, Fructus Forsythiae, Radix Glycyrrhizae of cardiotonic etc., and other protects the liver drugs strengthening spleen Semen Raphani, Fructus Perillae, Poria, Pericarpium Citri Reticulatae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Glycyrrhizae etc.
The Camphora causing resuscitation with aromatic drugs has cardiac stimulant effect, and SARS is particularly useful to prevention, removes this and adds Radix Astragali diuresis heart tonifying again, and the effect of the heart contraction of reinforcement is also arranged, and increases cardiac output, the diastole coronary vasodilator.Add the Radix Codonopsis blood pressure that can raise, promote the body metabolism; Both share invigorating the spleen and replenishing QI, and being furnished with Radix Glycyrrhizae is that four gentleman are main, and so compatibility brings out the best in each other.The sad impairing the liver again of SARS, this prescription can prevent and can treat, for preventing and treating the rare Chinese medicine of SARS.
Each amounts of components of medicine of the present invention has good efficacy in the following weight parts scope: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 1-5 part, Gypsum Fibrosum 3-30 part, Radix Glycyrrhizae 1-10 part, Radix Platycodonis 1-10 part, Radix Scutellariae 1-10 part, Rhizoma Coptidis 1-5 part, Cortex Phellodendri 1-10 part, Poria 1-5 part, Radix Et Rhizoma Rhei 1-3 part, Flos Lonicerae 1-5 part, Fructus Forsythiae 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part, Semen Raphani 2-10 part, Fructus Perillae 1-5 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1-10 part, Flos Chrysanthemi 1-10 part, Herba Taraxaci 1-10 part, Rhizoma Atractylodis 1-5 part.
Be preferably: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 1 part of Radix Platycodonis, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis.
Each amounts of components of medicine of the present invention can be: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 1-5 part, Gypsum Fibrosum 3-30 part, Radix Glycyrrhizae 1-10 part, Radix Platycodonis 1-10 part, Radix Scutellariae 1-10 part, Rhizoma Coptidis 1-5 part, Cortex Phellodendri 1-10 part, Poria 1-5 part, Radix Et Rhizoma Rhei 1-3 part, Flos Lonicerae 1-5 part, Fructus Forsythiae 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part, Semen Raphani 2-10 part, Fructus Perillae 1-5 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1-10 part, Flos Chrysanthemi 1-10 part, Herba Taraxaci 1-10 part, Rhizoma Atractylodis 1-5 part, Semen Sinapis Albae 1-5 part, Pericarpium Citri Reticulatae 1-5 part, Radix Rehmanniae 1-5 part, Herba Schizonepetae 1-5 part, Radix Puerariae 1-3 part, Radix Gentianae 1-3 part, Semen Phaseoli 1-20 part, Rhizoma Anemarrhenae 1-5 part, Camphora 0.5-2 part;
Be preferably: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 11 parts in Radix Glycyrrhizae, Radix Platycodonis part, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora.
Each amounts of components of medicine of the present invention can also be: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 1-5 part, Gypsum Fibrosum 3-30 part, Radix Glycyrrhizae 1-10 part, Radix Platycodonis 1-10 part, Radix Scutellariae 1-10 part, Rhizoma Coptidis 1-5 part, Cortex Phellodendri 1-10 part, Poria 1-5 part, Radix Et Rhizoma Rhei 1-3 part, Flos Lonicerae 1-5 part, Fructus Forsythiae 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part, Semen Raphani 2-10 part, Fructus Perillae 1-5 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1-10 part, Flos Chrysanthemi 1-10 part, Herba Taraxaci 1-10 part, Rhizoma Atractylodis 1-5 part, Semen Sinapis Albae 1-5 part, Pericarpium Citri Reticulatae 1-5 part, Radix Rehmanniae 1-5 part, Herba Schizonepetae 1-5 part, Radix Puerariae 1-3 part, Radix Gentianae 1-3 part, Semen Phaseoli 1-20 part, Rhizoma Anemarrhenae 1-5 part, Camphora 0.5-2 part, Radix Codonopsis 1-20 part, Radix Astragali 1-20 part, Semen Plantaginis 1-5 part, Semen Lepidii (Semen Descurainiae) 1-5 part.
Be preferably: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 11 parts of Radix Platycodoniss, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora, 1 part of Radix Codonopsis, 1 part of the Radix Astragali, 1 part of Semen Plantaginis, 1 part of Semen Lepidii (Semen Descurainiae).
Optimum formula of the present invention: 2 parts in Herba Ephedrae, 2 parts in Semen Armeniacae Amarum, 5 parts in Gypsum Fibrosum, 2 parts of Radix Platycodoniss, 2 parts of Radix Scutellariaes, 1 part of Rhizoma Coptidis, 2 parts of Cortex Phellodendris, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 2 parts of Fructus Forsythiaes, 2 parts of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 2 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Flos Chrysanthemis, 5 parts of Herba Taraxacis, 5 parts of Radix Codonopsis, 5 parts of the Radixs Astragali, 1 part of Pericarpium Citri Reticulatae, 0.1 part of Camphora.
Annotate: best prescription medicine 260 grams of reborning altogether, handle can get 150 grams after pulverizing.
Herba Ephedrae different name: imperial sand, inferior phase, inferior salt, Os Canitis; Composition: contain alkaloid 1-2%, wherein 40-90% is an ephedrine; Pharmacology: 1. ephedrine to the vasoconstriction action temperature and and lasting, very faint to vasorelaxation action, therefore be used for nasal mucosa swelling; Can make coronary vasodilation, increase coronary flow; Boosting is slowly lasting, can keep a few hours, and the rising of systolic pressure is remarkable than diastolic pressure; For heart powerful excitation is arranged also.2. as can excited cerebral cortex and subcortical center, cause mental excitation, have a sleepless night, tremble, symptom such as uneasiness with big therapeutic dose, also can excited respiratory center and vasomotor center, the effect of reviving when being poisoned, anesthetics is arranged.3. ephedrine is lasting to the spasmolysis of tracheal smooth muscle, and it is more obvious particularly to be in the spasmolysis of spasticity in bronchus; 4. skeletal muscle there is antifatigue effect.Function cures mainly: diaphoresis, relieving asthma, diuretic; Curing the wound cold table reality, fever with chills, headache nasal obstruction, arthralgia, cough and asthma, edema due to wind pathogen edema, dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella scratched where it itches.
The Radix Scutellariae different name: rotten intestinal, Huang Wen, rainbow win, through a kind of reed mentioned in ancient books, Radix Scutellariae, tsuchikane tea root; Composition: root contains in baicaligenin, baicalin, wogonin, the stem and leaf and contains scutellarin; Pharmacology: 1. antiinflammatory, antiallergic action, baicaligenin, baicalin is shunk by intestinal Mus isolated tracheal anaphylaxis and the whole animal allergic asthma all has mitigation; And collaborative with ephedrine, suppress the release of anaphylaxis amboceptor, thereby do not produce anaphylaxis, and can suppress anaphylaxis edema and inflammation; 2. wider antimicrobial spectrum is arranged, dysentery bacterium, bacillus pyocyaneus, staphylococcus, streptococcus, Diplococcus pneumoniae and encephalitis coccus are all had inhibitory action, decoct is done the larynx spraying; In vitro strain has inhibitory action to influenza virus PR8, can make it to alleviate pulmonary lesion behind the Mus infective virus and prolong the time-to-live; 3. refrigeration function is arranged; 4. the antihypertensive diuretic effect is arranged; 5. Radix Scutellariae and three yellow preparation (Rhizoma Coptidis, Radix Scutellariae, Radix Et Rhizoma Rhei 1: 1: 1) can make cholesterol reduce, and Radix Scutellariae can make blood glucose rise; Function cures mainly: the removing the relative excess fire removes damp and hot, hemostasis, antiabortive; Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leakage, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.
The Radix Platycodonis different name: BAIYAO, sharp as, stalk grass, Radix Platycodi, medicine greatly; Composition: root contains Saponin; Pharmacology: respiratory mucosa liquid secretory volume is significantly increased, and action intensity can be compared with ammonia chloride, is better than Radix Polygalae and inferior to senea; 2. zoopery is thought blood glucose is reduced, artificial rabbit diabetes, and the effect of blood sugar lowering is more remarkable; Function cures mainly: open lung qi dispersing gas, the evacuation of pus of eliminating the phlegm; Control exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.
Semen Raphani different name: Semen Raphani; The fatty oil of seed, volatile oil; Pharmacology: 1. Semen Raphani contains antibiotic substance, and its effective ingredient is a raphanin, and escherichia coli and staphylococcus are all had remarkable inhibitory action; Can be to growths such as streptococcus, pyococcus, streptococcus pneumoniae; 2. 6 kinds of dermatophytess such as Trichophyton concentricunm there is in various degree inhibitory action in vitro; Function cures mainly: make leave with rage down breathe heavily, promoting digestion and removing stagnation; Weigh after controlling cough phlegm dyspnea, stagnation of QI due to dyspepsia, abdominal distention uncomfortable in chest, dysentery.
The Rhizoma Coptidis different name: jade connects, Zhi Lian; Composition: contain alkaloids such as berberine 7-9%, coptisine; Pharmacology: 1. antibacterial: in vitro tests proof Rhizoma Coptidis or berberine all have stronger bacteriostasis to hemolytic chain bacterium, meningococcus, Diplococcus pneumoniae, vibrio cholera, anthrax bacillus and golden yellow golden staphylococci; Also effective to pneumobacillus, bordetella pertussis, clostridium tetani, tubercule bacillus etc.; The antibacterial action of Rhizoma Coptidis crude extract and pure berberine is consistent basically, the not low at least what chloromycetin of its clinical efficacy, streptomycin; 2. in the Embryo Gallus domesticus test, influenza virus, Newcastle virus all there are certain inhibitory action, pathogenic fungus are had extensively and significantly suppress, leptospira is had great killing action in test tube, anti-ameba effect is all arranged in external and body; 3. the effect of blood circulation to anesthesia or anesthetized animal not, all can cause blood pressure drops, and hypotensive effect and heart have nothing to do, and blood pressure lowering is relevant with vasodilation; 4. to the effect of flat flesh, vascular smooth muscle is played relaxation effect, uterus, bladder, bronchus, intestines and stomach etc. are all had excitation; Mouse Uterus then there is the paralysis effect; 5. berberine has choleretic effect, and to the chronic cholecystitis patient, oral have a good result; Anti-anemia effect is arranged; 6. anticancer, in tissue culture test, suppress the picked-up of Cellular respiration, oxygen and cause that the fatty of cell becomes; 7. the berberine low dose can be strengthened the process of excitation of mouse brain cortex, and heavy dose can weaken it; Function cures mainly: pathogenic fire purging dampness, detoxifcation parasite killing, row pyretic toxicity when controlling, typhoid fever, intenseness of heat are vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis, tell, nosebleed, hematochezia, quench one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, scald etc.
Cortex Phellodendri different name: bark of a cork tree wood, bark of a cork tree skin, Cortex Phellodendri; Composition: contain berberine; Pharmacology: Cortex Phellodendri and Rhizoma Coptidis contain more berberine equally, thus also broadly similar of its pharmacological action, but content is low than Rhizoma Coptidis; 1. antibacterial action: effective ingredient is a berberine.The Rhizoma Coptidis effect is strong one times than Cortex Phellodendri.2. hypotensive effect: to anesthetized animal vein or lumbar injection, can produce remarkable and persistent hypotensive effect, blood pressure lowering belongs to central; Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication; Control hematodiarrhoea have loose bowels, disappear cough, jaundice, nocturnal emission, stranguria with turbid discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.
Poria different name: Fu Tu, Poria, Poria, Song Ling; Composition: sclerotium contains β-pachyman, accounts for dry weight 93%; Pharmacology: 1. diuresis: the oral alcohol extract of rat has tangible diuresis; 2. antibacterial action: test tube finds no bacteriostasis; 3. the biotic experiment proof has direct relexation to intestine in vitro, and can reduce gastric acid; Function cures mainly: eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.
The Radix Glycyrrhizae composition: root and rhizome contain glycyrrhizin, liquiritin; Pharmacology: 1. contain the effect of adrenocortical hormone sample; 2. the effect of antiinflammatory and antiallergic action; 3. Detoxication; 4. antitussive effect can reduce the stimulation of pharyngeal mucosa, thus antitussive, its antitussive effect is a central, its intensity is similar to codeine; Function cures mainly: with middle emergency, lung moistening detoxifcation, coordinating the actions of various ingredients in a prescription.
Fructus Perillae different name: Fructus Perillae, FRUCTUS PERILLAE, wild flax, ferrum Fructus Perillae; Composition: fatty oil of seed (45.30%) and vitamin B; Function cures mainly: the therapeutic method to keep the adverse QI flowing downwards, expectorant, lung moistening, wide intestinal; Control cough with dyspnea, phlegm dyspnea, the stagnation of QI, constipation.
Gypsum Fibrosum different name: microlith, thin Gypsum Fibrosum, soft gypsum, Mirabilitum crystallina, white tiger; Composition: main component is the Fe of hydrous calcium sulfate, trace ++And Mg ++Pharmacology: antipyretic effect is arranged.MAXINGSHIGAN TANG has inhibitory action to influenza virus, mainly from Herba Ephedrae; Function cures mainly: give birth to and quench the thirst with expelling pathogenic factors from muscles for clearing heat, relieving restlessness; Control calentura, high fever does not move back, vexed coma, delirium are gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration.
The Semen Armeniacae Amarum different name: almond core, Fructus Pruni, wood are begun, Semen Armeniacae Amarum, bitter Mei Ren; Composition: contain that amygdalin is about 3%, fat grease proofing (almond oil) is about 50%, protein and free amino acid; Pharmacology: after for oral administration, amygdalin can be produced hydrocyanic acid and benzoic acid aldehyde by enzyme hydrolysis, common 1 gram Semen Armeniacae Amarum can produce 2.5 milligrams of hydrocyanic acids, hydrocyanic acid is an extremely toxic substance, and about 0.05 gram of people's lethal dose is taken a small amount of Semen Armeniacae Amarum, slowly decompose in vivo, unlikelyly cause poisoning, and be the effect of calm respiratory center, the antitussive and antiasthmatic effect is arranged; Function cures mainly: expelling phlegm for arresting cough, relieving asthma, intestine moistening; Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.
Radix Et Rhizoma Rhei composition: have discharge function, contain tannin not only but also anti-diarrhea effect is arranged; Pharmacology: 1. anti-diarrhea effect, because of containing tannin, so after generation is dropped, also cause constipation; 2. antibacterial action all has antibacterial action to the Ge Shi positive and Ge Shi negative bacteria; 3. can shorten blood clotting and stop blooding;
Function cures mainly: the poison that purges heat, removing mass stagnate, clots absorbing blood; Control the excess-heat constipation, delirium is gone mad, haematemesis, epistaxis, YANG jaundice edema, sudden and violent swelling ophthalmalgia etc.
Fructus Forsythiae different name: yerbadetajo seed, stick up son, ghost greatly; Composition: fruit contains forsythol, sterol compound, Saponin and flavonol glycoside; Pharmacology: 1. can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.; 2. other effects, effect, heart tonifying diuresis are told by the town; Function cures mainly: heat clearing away, detoxifcation, eliminating stagnation, detumescence; Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, uroschesis.
Flos Chrysanthemi pharmacology: 1. antipathogen effect: golden staphylococcus and streptococcus, mycobacterium hominis are had some inhibitory action external; 2. antiinflammatory action; 3. strengthen capillary resistance; Function cures mainly: wind and heat dispersing, soothing the liverly make eye bright, detoxify, control headache, dizzy, conjunctival congestion lacrimation.
Flos Lonicerae different name: Flos Lonicerae, Flos Lonicerae, little egret flower, Soviet Union's flower, JINHUA, golden rattan, Flos Lonicerae; Composition: flower contains luteolin, inositol about 1% and white glycoside, tannin etc.; Pharmacology: 1. various bacteria (Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, bacillus pyocyaneus, bordetella pertussis, vibrio cholera and staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus etc.) is all had inhibitory action, some common bacteria of chronic tracheitis (streptococcus pneumoniae, alpha streptococcus, micrococcus catarrhalis etc.) is also had bacteriostasis external; But its antibacterial efficacy of autoclave sterilization appreciable impact; 2. cancerous cell is not had direct effect, but can alleviate the reduction of suffering from catalase and activity of cholinesterase in the cancer animal livers; Function cures mainly: heat-clearing and toxic substances removing; Control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula; Control the fever caused by exogenous pathogens cough.
Rhizoma Polygoni Cuspidati different name: tiger cane, bitter cane, sour cane, speckle cane, wild RHIIZOMA COPTIDIS; Composition: root and stem and leaf all contain emodin, physcione; Pharmacology: 1. antibacterial action: experiment in vitro, Rhizoma Polygoni Cuspidati decocting liquid (25%) all has inhibitory action to staphylococcus aureus, micrococcus catarrhalis, first type or group B streptococcus, escherichia coli, bacillus pyocyaneus; 2. influenza virus, poliovirus, encephalitis b virus, herpes simplex virus all there is obvious inhibitory action; 3. intravenous rabbit injection can cause hypoglycemia shock; Function cures mainly: expelling wind and removing dampness, dissipating blood stasis to promote menstruationg, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lump in the abdomen, anal fistula hematochezia fall Piao's damage, scald.
Rhizoma Pinelliae different name: the ground pearl Rhizoma Pinelliae, three step jumpings, YEYUTOU, corbie eye, Thunder God; Composition: the stem piece contains volatile oil, little fat; Pharmacology: 1. Antitussive and Expectorant Effect has mitigation to throat pain; 2. effect is told in the town: the Rhizoma Pinelliae or Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) all have antiemetic effect; 3. Detoxication: the derivative of the contained gluconic acid aldehyde of the Rhizoma Pinelliae has significant Detoxication; Toxicity: secondly Rhizoma Pinelliae toxicity maximum is Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), steam the Rhizoma Pinelliae, Alumen Rhizoma Pinelliae toxicity minimum; Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass is controlled damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm, headache, dizzy sleeplessness, outer subduing inflammation.
Rhizoma Atractylodis different name: red art, horse Ji, blue or green art, magic arts; Composition: root contains volatile oil, and its main component is atractylol, atractylone; Pharmacology: 1. blood glucose descends, and the back of taking medicine did not see that blood glucose rose in 4~17 days; 2. (6 cubic metres of laboratorys are respectively with 200 grams for Rhizoma Atractylodis, Folium Artemisiae Argyi sootiness sterilization, sootiness 2 hours) bacillus, golden yellow staphylococcus such as tuberculosis, large intestine, hay, green pus there is significant sterilization effect, similar to formalin, and be better than the sterilization of ultraviolet and lactic acid.Function cures mainly: spleen invigorating, dampness, resolving depression, ward off dirtyly, control moist tired spleen, asthenia is thought to crouch, gastral cavity spleen abdominal distention, inappetence, vomit, have loose bowels, anemofrigid-damp arthralgia, sufficient fistula, nyctalopia, dehumidifying diaphoresis merit maximum.
Herba Taraxaci different name: wild duck Herba Taraxaci, grandmother's fourth, Herba Violae, wood pigeon English, Herba crotalariae albidae; Composition: herb contains taraxasterol, choline, inulin and pectin; Pharmacology: golden staphylococci, Hemolytic streptococcus are had stronger bactericidal action, bacillus such as coccuses such as pneumonia, meningitis, mucositis, diphtheria, green pus, distortion, dysentery, typhoid fever are also had certain bactericidal action; Animal choleretic effect is arranged on one's body, effective to gallbladder spasm and calculosis clinically; Diuresis is arranged, particularly effective to the portal vein edema; Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation, control acute mastitis, lymph arteries and veins inflammation, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, hepatitis, cholecystitis, urinary tract infection.All produce effect from treatment hepatitis, viral influenza, antivirus action is arranged probably.
Radix Astragali pharmacology: 1. diuresis, oral decoct have diuresis and sodium output to increase; 2. to the cardiovascular effect, the heart contraction of reinforcement, myocardial contraction, diastole coronary vasodilator are arranged; 3. hypotensive effect; 4. strong effect; Function cures mainly: benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, invigorating the spleen and replenishing QI.
Radix Codonopsis pharmacology: 1. can make blood sugar increasing, and some adrenolytic is arranged; 2. hypotensive effect; 3. can promote the body metabolism.
The present invention can be made into capsule and oral liquid, and method is as follows:
Pulverize and packing
One, capsule
1. pulverize
(1) impurity is checked, removed to each medicine respectively, wash 2~3 times degree of being with clear water with clean;
(2) pull dry in the sun out, get final product to dry tack free;
(3) put into the baking box baking, temperature is advisable with 80 ℃; Stirred once in per 10 minutes, totally three times, with inside and outside reaching all intensive drying be as the criterion;
(4) each medicinal pulverizer is pulverized;
(5) cross 120 mesh sieves;
2. packing
(1) medicated powder is respectively charged in the capsule;
(2) each capsule powder charge powder is 250 milligrams, promptly contains biological 250 milligrams.
Consumption, instructions of taking, toxic and side effects, taboo and points for attention:
1. consumption: each 2~4,3 times on the 1st, 6 of maximum dose 1 time, 1 day 18, or follow the doctor's advice;
2. instructions of taking: swallows with eliminating cold for resuscitation water in the food back, better as taking with ginger syrup, but diabetics can not be with sugared, and available Jiang Shui swallows;
3. toxic and side effects: the slightly poisonous and violent medicine of this medicine, unless emergency and severe disease should not be with a large amount of, consumption routinely, One's personal safety need not cause any anxiety;
4. when taking for a long time, treat that sx gets final product decrement;
5. taboo:, the careful usefulness of allergies person is arranged to Herba Ephedrae, Semen Armeniacae Amarum allergy sufferers forbidding;
6. points for attention: (1) should cooperate the western modern medicine co-therapy to the emergency and severe disease patient, does not specially rely on this product: (2) are ban on opium-smoking and the opium trade, wine between the treatment time limit; (3) above-mentioned for adult's amount, infant taking amount are 1/4~1/10, and should under the doctor instructs, take.
Two, oral liquid
1. pulverize (1), (2) same capsule;
(3) decoct with conventional decoction, boil in the medicinal liquid impouring container of back, all the other medicinal liquids add water again to be continued to decoct;
(4) concentrate it after repeatedly medicinal liquid mixes;
(5) medicinal liquid of Nong Suoing is glue and is as the criterion;
(6) add distilled water diluting, extremely golden yellow liquid is good, pours into after the stirring in the peace bottle, and making every bottle of crude drug is the doubly amount of capsule;
(7) with the sterilization of SYX-4.8 water-bath type steriliser;
(8) cooling back sealing.
The same capsule of usage, all the other all same capsules, consumption are half amount of capsule.
Animal toxicology test of the present invention:
Animal Quantity The feeding dose Number of days The result
Adult cat 6 100 milligrams of every days 30 days Have no side effect
Adult dog 4 200 milligrams of every days 30 days Have no side effect
Chicken grows up 4 50 milligrams of every days 30 days Have no side effect
Chicken (January) 20 10 milligrams of every days 30 days Do not find toxic and side effects
Annotate: 20 chickens, wherein 3 natural deaths, actual is 17.
Result of the test is not found toxic and side effects, so proof avirulence of the present invention.
The case statistics:
In part case, 350 parts of cases are selected in sampling surplus 2000, and its statistical result is as follows:
Name of disease The example number Recovery from illness Produce effects Effectively Invalid
Intrapulmonary infection (comprising pneumonia) 39 7 11 16 5
Bronchitis 109 31 33 36 9
Inflammation of upper respiratory tract 62 24 18 17 3
Flu 94 30 31 26 7
Other 46 11 15 10 10
Amount to 350 103 108 105 34
Effective percentage 90.29%, inefficiency 9.71%.
The present invention can treat intrapulmonary infection effectively, and effective percentage can reach more than 90%, and can prevent and treat atypical pneumonia.
The specific embodiment
Embodiment 1:
Get 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 1 part of Radix Platycodonis, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, Rhizoma Polygoni Cuspidati part, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, standby;
The present invention can be made into capsule and oral liquid, and method is as follows:
Pulverize and packing
One, capsule
1. pulverize
(1) impurity is checked, removed to each medicine respectively, wash 2~3 times degree of being with clear water with clean;
(2) pull dry in the sun out, get final product to dry tack free;
(3) put into the baking box baking, temperature is advisable with 80 ℃; Stirred once in per 10 minutes, totally three times, with inside and outside reaching all intensive drying be as the criterion;
(4) each medicinal pulverizer is pulverized;
(5) cross 120 mesh sieves;
2. packing
(3) medicated powder is respectively charged in the capsule;
(4) each capsule powder charge powder is 250 milligrams, promptly contains biological 250 milligrams.
6. points for attention: (1) should cooperate the western modern medicine co-therapy to the emergency and severe disease patient, does not specially rely on this product; (2) ban on opium-smoking and the opium trade, wine between the treatment time limit; (3) above-mentioned for adult's amount, infant taking amount are 1/4~1/10, and should under the doctor instructs, take.
Two, oral liquid
1. pulverize
(1), (2) same capsule;
(3) decoct with conventional decoction, boil in the medicinal liquid impouring container of back, all the other medicinal liquids add water again to be continued to decoct;
(4) concentrate it after repeatedly medicinal liquid mixes;
(5) medicinal liquid of Nong Suoing is glue and is as the criterion;
(6) add distilled water diluting, pour into after the stirring in the peace bottle, making every bottle of crude drug is the doubly amount of capsule;
(7) with the sterilization of SYX-4.8 water-bath type steriliser;
(8) cooling back sealing.
Embodiment 2:
Get 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 1 part of Radix Platycodonis, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora, standby;
Preparation method is with embodiment 1.
Embodiment 3:
Get 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 1 part of Radix Platycodonis, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora, 1 part of Radix Codonopsis, 1 part of the Radix Astragali, 1 part of Semen Plantaginis, 1 part of Semen Lepidii (Semen Descurainiae), standby;
Preparation method is with embodiment 1.
Embodiment 4:
Get 2 parts in Herba Ephedrae, 2 parts in Semen Armeniacae Amarum, 5 parts in Gypsum Fibrosum, 2 parts of Radix Platycodoniss, 2 parts of Radix Scutellariaes, 1 part of Rhizoma Coptidis, 2 parts of Cortex Phellodendris, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 2 parts of Fructus Forsythiaes, 2 parts of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 2 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 3 parts of Flos Chrysanthemis, 5 parts of Herba Taraxacis, 5 parts of Radix Codonopsis, 5 parts of the Radixs Astragali, 1 part of Pericarpium Citri Reticulatae, 0.1 part of Camphora, standby;
Preparation method is with embodiment 1.

Claims (8)

1, a kind of Chinese medicine for the treatment of intrapulmonary infection is characterized in that it mainly is made up of the following raw materials in part by weight medicine: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 1-5 part, Gypsum Fibrosum 3-30 part, Radix Glycyrrhizae 1-10 part, Radix Platycodonis 1-10 part, Radix Scutellariae 1-10 part, Rhizoma Coptidis 1-5 part, Cortex Phellodendri 1-10 part, Poria 1-5 part, Radix Et Rhizoma Rhei 1-3 part, Flos Lonicerae 1-5 part, Fructus Forsythiae 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part, Semen Raphani 2-10 part, Fructus Perillae 1-5 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1-10 part, Flos Chrysanthemi 1-10 part, Herba Taraxaci 1-10 part, Rhizoma Atractylodis 1-5 part.
2, medicine according to claim 1, wherein the consumption of each crude drug is: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 1 part of Radix Platycodonis, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis.
3, medicine according to claim 1, wherein crude drug also has: Semen Sinapis Albae 1-5 part, Pericarpium Citri Reticulatae 1-5 part, Radix Rehmanniae 1-5 part, Herba Schizonepetae 1-5 part, Radix Puerariae 1-3 part, Radix Gentianae 1-3 part, Semen Phaseoli 1-20 part, Rhizoma Anemarrhenae 1-5 part, Camphora 0.5-2 part.
4, medicine according to claim 3, wherein the consumption of each crude drug is: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 11 parts in Radix Glycyrrhizae, Radix Platycodonis part, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora.
5, medicine according to claim 3, wherein crude drug also has: Radix Codonopsis 1-20 part, Radix Astragali 1-20 part, Semen Plantaginis 1-5 part, Semen Lepidii (Semen Descurainiae) 1-5 part.
6, medicine according to claim 5, wherein the consumption of each crude drug is: 1 part in Herba Ephedrae, 1 part in Semen Armeniacae Amarum, 3 parts in Gypsum Fibrosum, 1 part in Radix Glycyrrhizae, 11 parts of Radix Platycodoniss, 1 part of Radix Scutellariae, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part in Poria, 1 part of Radix Et Rhizoma Rhei, 1 part of Flos Lonicerae, 1 part of Fructus Forsythiae, 1 part of Rhizoma Polygoni Cuspidati, 2 parts of Semen Raphanis, 1 part of Fructus Perillae, 1 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 part of Flos Chrysanthemi, 1 part of Herba Taraxaci, 1 part of Rhizoma Atractylodis, 1 part of Semen Sinapis Albae, 1 part of Pericarpium Citri Reticulatae, 1 part in the Radix Rehmanniae, 1 part of Herba Schizonepetae, 1 part of Radix Puerariae, 1 part of Radix Gentianae, 1 part of Semen Phaseoli, 1 part of the Rhizoma Anemarrhenae, 0.5 part of Camphora, 1 part of Radix Codonopsis, 1 part of the Radix Astragali, 1 part of Semen Plantaginis, 1 part of Semen Lepidii (Semen Descurainiae).
7, according to the preparation method of each described medicine of claim 1 to 6, it may further comprise the steps:
(1) impurity is checked, removed to each medicine respectively, wash 2~3 times degree of being with clear water with clean;
(2) pull dry in the sun out, get final product to dry tack free;
(3) put into the baking box baking, temperature is advisable with 80 ℃; Stirred once in per 10 minutes, totally three times, with inside and outside reaching all intensive drying be as the criterion;
(4) each medicinal pulverizer is pulverized;
(5) cross 120 mesh sieves;
(6) medicated powder is respectively charged in the capsule;
(7) each capsule powder charge powder is 250 milligrams, promptly contains biological 250 milligrams.
8, according to the preparation method of each described medicine of claim 1 to 6, it may further comprise the steps:
(1) impurity is checked, removed to each medicine respectively, wash 2~3 times degree of being with clear water with clean;
(2) pull dry in the sun out, get final product to dry tack free;
(3) decoct with conventional decoction, boil in the medicinal liquid impouring container of back, all the other medicinal liquids add water again to be continued to decoct;
(4) concentrate it after repeatedly medicinal liquid mixes;
(5) medicinal liquid of Nong Suoing is glue and is as the criterion;
(6) add distilled water diluting, extremely golden yellow liquid is good, pours into after the stirring in the peace bottle, and making every bottle of crude drug is the doubly amount of capsule;
(7) with the sterilization of SYX-4.8 water-bath type steriliser;
(8) cooling back sealing.
CN 200310109919 2003-10-17 2003-10-17 Chinese medicine for treating intrapulmonic infection and SARS Expired - Fee Related CN1251732C (en)

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