CN105362991A - Oral medicine for treating pertussis and preparation method thereof - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and aims to provide an oral medicine for treating pertussis according to a know mechanism of the traditional Chinese medicine on the pertussis. The medicine comprises the following various components in parts by mass: 6-15 g of radix ophiopogonis, 5-12 g of semen raphani, 5-15 g of root of radix stemonae, 10-20 g of asparagus cochinchinensis, 3-12 g of perillaseed, 4-8 g of snakegourd seeds, 8-15 g of almond, 3-10 g of Citrus reticulata Blanco, 3-9 g of fresh ginger and 3-9 g of pericarpium citri reticulatae. The oral medicine is good in efficacy, takes effect quickly, and is a traditional Chinese medicines formula capable of treating both symptoms and root causes.

Description

One treats pertussal endo-medicine and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, be specifically related to one and treat pertussal endo-medicine, particularly for the field of the endo-medicine and preparation method thereof of pertussis patient.

Background technology

Pertussis is commonly called as pertussis, cough with sound like cormorant cry, and neonate and infant patient easily suffocate threat to life.It is characterized by paroxysmal spasmodic cough, cough end is with special air-breathing roar, and the course of disease is longer, can reach even about 3 months several weeks, therefore have the title of pertussis.Children baby easily have when suffering from primary disease suffocate, the complication such as pneumonia, encephalopathy, case fatality rate is high.Young baby and Adult Onset have and increase trend in recent years, and in death, 40% is the infant within 5 months.Apply antibiotic therapy early, general prognosis bona.These sick various places all over the world, generally in distributing shape, can happening and prevelence in mechanism of child collective.The whole year all can fall ill, and be many with winter-spring season, can be extended down to the end of spring and the beginning of summer, even peak is in 6,7,8 three month.Patient and Asympto matic carrier are the sources of infection, be all infectious, pass through droplet transmission from incubation period by the 6th week.Crowd is to the general susceptible of this disease, and the case of about 2/3 is less than 7 years old children's, especially many with less than 5 years old person.The specific antibody obtained from parent because of infant is few, susceptible the most.

So, with regard to how finding one effectively can treat above-mentioned pertussal medicine, be the problem that we should solve at present.

Summary of the invention

Along with the development of China's Chinese medicine, in treatment pertussis, people appreciate the advantage of the above-mentioned disease of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, for the above-mentioned pertussal present situation of existing western medical treatment, the object of the invention is to be to provide one to treat pertussal endo-medicine, to solve pertussis patient restorative problem early.This medicine be with common Chinese medicine for raw material, there is instant effect, the feature such as evident in efficacy, and effectively can treat above-mentioned pertussis one disease.

For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide one to treat pertussal endo-medicine and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 6 ~ 15g, Semen Raphani 5 ~ 12g, Radix Stemonae 5 ~ 15g, Radix Asparagi 10 ~ 20g, Fructus Perillae 3 ~ 12g, Semen Trichosanthis 4 ~ 8g, Semen Armeniacae Amarum 8 ~ 15g, Exocarpium Citri Rubrum 3 ~ 10g, Rhizoma Zingiberis Recens 3 ~ 9g, Pericarpium Citri Reticulatae 3 ~ 9g.

One treats pertussal endo-medicine and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 7 ~ 13g, Semen Raphani 6 ~ 10.5g, Radix Stemonae 7 ~ 13g, Radix Asparagi 12 ~ 17g, Fructus Perillae 4 ~ 10.5g, Semen Trichosanthis 5 ~ 7g, Semen Armeniacae Amarum 9 ~ 13g, Exocarpium Citri Rubrum 4 ~ 10.5g, Rhizoma Zingiberis Recens 4 ~ 8g, Pericarpium Citri Reticulatae 4 ~ 8g.

One treats pertussal endo-medicine and preparation method thereof, it is characterized in that, each component of the medicine of described " preferred plan " and mass parts thereof are than as follows:

Radix Ophiopogonis 11g, Semen Raphani 9g, Radix Stemonae 12g, Radix Asparagi 15g, Fructus Perillae 9g, Semen Trichosanthis 6g, Semen Armeniacae Amarum 11g, Exocarpium Citri Rubrum 9g, Rhizoma Zingiberis Recens 7g, Pericarpium Citri Reticulatae 7g.

One treats pertussal endo-medicine and preparation method thereof, it is characterized in that, described method comprises the steps to be prepared from:

A, first raw material Chinese medicine is picked decontamination and dust after, decoct a drug wrapped than being ground into coarse respectively according to mass parts;

B, the raw material Chinese medicine wrapped put into cold boiled water and soak 30 minutes, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 33mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 31mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 600 milliliters of 50%, for subsequent use after packed sealing.

One treats pertussal endo-medicine and preparation method thereof, it is characterized in that, described instructions of taking is: divided by the herb liquid prepared and take for two days, the morning, noon and afternoon service once, dosage 100 milliliters/time, taking medicine before meal.Take medicine 15-35 days, transference cure, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine.The present invention selects wherein modal Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:

Radix Ophiopogonis, nature and flavor: sweet, micro-hardship is slightly cold, have nourishing YIN and moistening the lung, effect that stomach reinforcing clears away heart-fire, are used for the treatment of the diseases such as lung-dryness syndrome due to deficiency of YIN, dry cough expectorant are thick, chronic cough spitting of blood, Tianjin few thirsty, vexed insomnia, dryness of the intestine constipation;

Semen Raphani, nature and flavor: pungent, sweet, flat, have effect of the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm, be used for the treatment of retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant stops up and breath with cough;

Radix Stemonae, nature and flavor: sweet, bitter, tepor, have effect of nourishing the lung to arrest cough, parasite killing delousing, be used for the treatment of that new chronic cough is coughed, pulmonary tuberculosis, pertussis, enterobiasis, body louse, tinea scabies;

Radix Asparagi, nature and flavor: sweet, bitter, cold, have YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire, be used for the treatment of dryness of the lung dry cough, cough due to consumptive disease, thirsty, the vexed insomnia of Tianjin wound, interior-heat quenched one's thirst, dryness of the intestine constipation, diphtheria, anticancer, the clear gesture that relieves internal heat is reduced phlegm, nourshing Yin and drynsessmoistening prescription;

Fructus Perillae, nature and flavor: pungent, warm, have sending down the abnormal ascending QI expectorant, relieving asthma, effect of intestine moistening, are used for the treatment of expectorant and stop up QI rising in reverse order, cough and asthma, dryness of the intestine constipation;

Semen Trichosanthis, nature and flavor: sweet, micro-hardship, cold, have lung moistening dry, effect of fire falls, be used for the treatment of cough, clearing away phlegm tie, only quench one's thirst, sharply to defecate, subduing inflammation sore;

Semen Armeniacae Amarum, nature and flavor: bitter in the mouth, slightly warm in nature, have effect of sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation, are used for the treatment of that cough and asthma, fullness in the chest abundant expectoration, blood deficiency Tianjin are withered, dryness of the intestine constipation;

Exocarpium Citri Rubrum, nature and flavor: acrid, bitter, warm, have cold expelling, dampness, promoting the circulation of QI, effect of expectorant, be used for the treatment of cough due to wind and cold, itching of the throat abundant expectoration, food stagnation are got sick from drinking too much wine, vomiting and nausea painful abdominal mass is vexed;

Rhizoma Zingiberis Recens, nature and flavor: tepor, pungent, have effect of the cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing, are used for the treatment of anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough;

Pericarpium Citri Reticulatae, nature and flavor: acrid in the mouth, hardship, warm in nature, there is effect of regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, diuretic relieving constipation, be used for the treatment of incoordination between the spleen and stomach, abdominal distention, anorexia, vomiting hiccup, accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm full vexed, the vertigo, edema, dysuria, constipation, acute mastitis scabies, middle fish Eriocheir sinensis poison, alcoholism etc.

Medicine of the present invention is based on the pertussal differential diagnosis of diseases of Chinese traditional treatment and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to pertussis one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.

Detailed description of the invention

The present invention is exactly a kind of Chinese medicine formula proposed for above-mentioned pertussal treatment, and the medicine effect adopting this formula to prepare is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Be described in further detail below in conjunction with the specific embodiment of the present invention:

Embodiment 1:

One treats pertussal endo-medicine and preparation method thereof, and each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 11g, Semen Raphani 9g, Radix Stemonae 12g, Radix Asparagi 15g, Fructus Perillae 9g, Semen Trichosanthis 6g, Semen Armeniacae Amarum 11g, Exocarpium Citri Rubrum 9g, Rhizoma Zingiberis Recens 7g, Pericarpium Citri Reticulatae 7g.

Embodiment 2:

One treats pertussal endo-medicine and preparation method thereof, and each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 13g, Semen Raphani 10.5g, Radix Stemonae 13g, Radix Asparagi 17g, Fructus Perillae 10.5g, Semen Trichosanthis 7g, Semen Armeniacae Amarum 13g, Exocarpium Citri Rubrum 10.5g, Rhizoma Zingiberis Recens 8g, Pericarpium Citri Reticulatae 8g.

Embodiment 3:

One treats pertussal endo-medicine and preparation method thereof, and each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 15g, Semen Raphani 12g, Radix Stemonae 15g, Radix Asparagi 20g, Fructus Perillae 12g, Semen Trichosanthis 8g, Semen Armeniacae Amarum 15g, Exocarpium Citri Rubrum 10g, Rhizoma Zingiberis Recens 9g, Pericarpium Citri Reticulatae 9g.

Model case:

Through clinical conditions pertussis patient totally 100 examples, the age is more than 5 years old 41 routine, has 59 examples to be less than 5 years old.98 examples of fully recovering in 100 routine patients, effective 2 examples, total effective rate reaches 100%.After treatment, obtain clinical recovery.

Claims (3)

1. treat a pertussal endo-medicine, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 6 ~ 15g, Semen Raphani 5 ~ 12g, Radix Stemonae 5 ~ 15g, Radix Asparagi 10 ~ 20g, Fructus Perillae 3 ~ 12g, Semen Trichosanthis 4 ~ 8g, Semen Armeniacae Amarum 8 ~ 15g, Exocarpium Citri Rubrum 3 ~ 10g, Rhizoma Zingiberis Recens 3 ~ 9g, Pericarpium Citri Reticulatae 3 ~ 9g.

2. the pertussal endo-medicine for the treatment of according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 7 ~ 13g, Semen Raphani 6 ~ 10.5g, Radix Stemonae 7 ~ 13g, Radix Asparagi 12 ~ 17g, Fructus Perillae 4 ~ 10.5g, Semen Trichosanthis 5 ~ 7g, Semen Armeniacae Amarum 9 ~ 13g, Exocarpium Citri Rubrum 4 ~ 10.5g, Rhizoma Zingiberis Recens 4 ~ 8g, Pericarpium Citri Reticulatae 4 ~ 8g.

3. the pertussal endo-medicine for the treatment of according to claim 1 and 2, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Ophiopogonis 11g, Semen Raphani 9g, Radix Stemonae 12g, Radix Asparagi 15g, Fructus Perillae 9g, Semen Trichosanthis 6g, Semen Armeniacae Amarum 11g, Exocarpium Citri Rubrum 9g, Rhizoma Zingiberis Recens 7g, Pericarpium Citri Reticulatae 7g.