CN106620213A

CN106620213A - Traditional Chinese medicinal composition for preventing and controlling livestock cough-asthma and preparation method thereof

Info

Publication number: CN106620213A
Application number: CN201611241781.9A
Authority: CN
Inventors: 牛卫宁; 尹朋; 梁冰
Original assignee: Most Cas (beijing) Technology Development Co Ltd
Current assignee: Most Cas (beijing) Technology Development Co Ltd
Priority date: 2016-12-29
Filing date: 2016-12-29
Publication date: 2017-05-10

Abstract

The invention provides a traditional Chinese medicinal composition for treating livestock cough-asthma. The Chinese medicinal composition is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 600 to 1,000 parts of snow pears (fresh), 60 to 140 parts of lily, 10 to 60 parts of radix platycodonis, 10 to 40 parts of pericarpium citri reticulatae, 10 to 50 parts of fruit of purple perilla, 10 to 60 parts of japanese knotweed, 10 to 40 parts of negundo chastetree fruit, 10 to 40 parts of rhizoma pinelliae preparata and 10 to 60 parts of snakegourd fruit.

Description

A kind of Chinese medicine composition of preventing and treating livestock and poultry cough illness and preparation method thereof

Technical field

The invention belongs to Chinese medicine compound prescription field, is related to a kind of Chinese medicine composition for treating livestock and poultry cough and asthma and preparation method thereof.

Background technology

Pig cough illness is a kind of chronic respiratory tract disease for being caused pig by mycoplasma hyopneumoniae, is called pig endemicity lung Inflammation, is a kind of chronic lung disease of pig, and main clinic symptoms are to cough and pant.Cardinal symptom is cough, asthma.The sick initial stage is short Promote, dry cough, while flowing out a small amount of serosity nose liquid, canescence mucus or purulence nose liquid are flowed when seriously ill, it is existing that asthma occurs in mid-term As.Normally, appetite is without significant change for body temperature.Sick stage asthma increases, and dehisces to breathe, and lassitude, pig body is become thin, no Hope is walked about.

Pig cough illness is most commonly seen with autumn and winter, and different cultivars, the pig at age can infect.Sucking pig is to be easiest to infection, Next to that milking sow, in chronic process or subclinical infection more than Adult Pig.The incidence of disease of pig cough and asthma is higher, and feed-weight ratio increases after morbidity Plus, poor growth, feed consumption rate also showed increased, cause feeding cost to increase, economic loss is serious.Therefore, it is badly in need of a kind of high treatment The Chinese medical extract of effect, the preventing and treating piglet cough and asthma of low-residual, can effectively reduce cough and asthma, significantly reduce the morbidity of porcine respiratory disease Rate.

Chicken is breathed with cough the extensive generation of disease (the dyspneic disease based on symptom of breathing with cough temporarily is referred to as disease of breathing with cough), provisions chicken Production causes larger economic loss.This course of disease is different in size, there is several days, Shi Jitian, or even is extended to and delivers for sale, hence it is evident that Reduce the economic benefit of colony.Pathogenic factor is more because bacterium, virus, metabolism, raising are not good at causing.The present invention is provided in one kind Medicine compound, it can reduce sucking pig cough and asthma number of times during large scale of pig farm, improve feed intake, whet the appetite, Can be applicable in large scale of pig farm factory.

The content of the invention

It is an object of the invention to provide a kind of highly effective and safe, the Chinese medicine composition for improving feed intake, treating livestock and poultry cough illness And preparation method thereof.

To achieve these goals, the technical solution adopted in the present invention is as follows：

A kind of Chinese medicine composition for treating livestock and poultry cough illness, is prepared from by the Chinese medicine material medicine of following weight proportioning： 600-1000 part snow pears (fresh), 60-140 part lilies, 10-60 part balloonflower roots, 10-40 part dried orange peels, 10-50 part perilla seeds, 10-60 parts Giant knotweed, 10-40 part fruits of negundo, 10-40 part prepared RHIZOMA PINELLIZE without adju-vant, 10-60 part Snakegourd Fruits.

Preferably, it is prepared from by the Chinese medicine material medicine of following weight proportioning：700-900 part snow pears (fresh), 70- 130 parts of lilies, 20-40 part balloonflower roots, 15-35 part dried orange peels, 20-40 part perilla seeds, 20-50 part giant knotweeds, 15-35 part fruits of negundo, 15- 35 parts of prepared RHIZOMA PINELLIZE without adju-vant, 20-50 part Snakegourd Fruits.

It is furthermore preferred that what it was prepared from by the Chinese medicine material medicine of following weight proportioning：750-850 part snow pears (fresh), 80- 120 parts of lilies, 25-35 part balloonflower roots, 20-30 part dried orange peels, 25-35 part perilla seeds, 30-40 part giant knotweeds, 20-30 part fruits of negundo, 25- 30 parts of prepared RHIZOMA PINELLIZE without adju-vant, 30-40 part Snakegourd Fruits.

The Chinese medicine composition for the treatment of livestock and poultry cough illness of the present invention, is powder, capsule, oral liquid, granule, ball Agent or tablet.

The preparation method of the Chinese medicine composition of the present invention, step is as follows：

1) the fresh snow pear of recipe quantity is weighed, snow pear juice is squeezed to obtain, it is standby；It is snow pear residue and the lily of recipe quantity, balloonflower root, old Skin, perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight is extracted for the 8-15 times of alcohol reflux for measuring water or 40%-70% 2-3 time, each 1-2 hours are filtered, and merge extract and snow pear juice, be evaporated to relative density 1.20-1.28 (50 DEG C), Drying under reduced pressure is into dry cream；

2) dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mixed, prepare capsule, powder, granule Or tablet.

Wherein, step 1) in, the fresh snow pear of recipe quantity is weighed, snow pear juice is squeezed to obtain, it is standby；Snow pear residue and recipe quantity Lily, balloonflower root, dried orange peel, perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight measures water or 50%-60% for 10-12 times Alcohol reflux extract 2 times, each 1-2 hours.

Present invention additionally comprises the Chinese medicine composition of the present invention is in the medicine for treating or preventing livestock and poultry cough illness is prepared Application.

In the present invention, snow pear is monarch drug in a prescription, and lily is ministerial drug, and the effect of each component is as follows：

Snow pear (fresh)：Snow pear, pears name, meat tenderness Bai Ruxue, therefore claim, it is a kind of common fruit.It is sweet cold in nature, have profit of promoting the production of body fluid The effect of dry, clearing heat and eliminating phlegm, nourishing blood and promoting granulation, it is particularly suitable for autumn edible.According to《Compendium of Materia Medica》Record, " pears person, profit, its property It is descending fluent." it is medicinal to control wind-heat, moistening lung, the cool heart, dissolving phlegm, fall fire, removing toxic substances.Medical research proves that pears truly have moistening lung clear Dry, relieving cough and reducing sputum, nourishing blood and promoting granulation effect.Therefore the throat that the patient of acute tracheitis and the infection of the upper respiratory tract occurs is done, Itch, pain, sound is mute, phlegm is thick, constipation, urinate red, eliminating the phlegm have good effect.Bright Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica two pears of fruit》:Newborn pears are Snow pear ... can cure the disease.

Lily：For liliaceous plant tiger lily Lilium lancifolium Thunb., lily Lilium brownii The dry meat scale leaf of F.E.Brown var.viridulum Baker or Lilium tenuifolium Lilium Pumilum DC..Autumn Excavation, cleans, and strips scale leaf, puts in boiling water and slightly scalds, and is dried.It is sweet, tremble with fear.The thoughts of returning home, lung channel.Function Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.With In yin chronic cough, blood-stained sputum, dysphoria palpitates with fear, insomnia and dreamful sleep is absent-minded.《Sheng Nong's herbal classic》：It is sweet, put down.Cure mainly perverse trend Abdominal distension, pained, sharp stool, urine, tonifying middle-Jiao and Qi.《Haigoushen》：Make, it is slightly poisonous.Main hundred evil ghosts and goblins, weep more than, except epigastric oppression Full pain, control tinea pedis heat cough it is inverse.

Balloonflower root：For the dry root of Campanulaceae balloonflower root Platycodon grandiflorum (Jacq.) A DC..Spring, Qiu Erji excavate, clean, remove fibrous root, take advantage of it is fresh peel off crust or do not remove crust, be dried.It is bitter, pungent, put down.Return lung Jing.Function is declared Lung, profit pharynx, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, uncomfortable in chest smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, and sore purulence is not into bursting.《Not Record》：Sharp the five internal organs stomach, replenishing blood and vital energy, except fever and chills, wandering arthritis, middle benefit gas disappear paddy, treat laryngopharynx pain.《Haigoushen》：Diarrhea is controlled, product is gone in blood-breaking Gas, disappear accumulation, sputum, and main lung heat shortness of breath coughs inverse, except crymodynia in abdomen, dislikes and pediatric epilepsy scared in master.《Amplification on Materia Medica》：Control lung carbuncle. 《Pearl sac》：Sore-throat is treated, sharp lung qi controls nasal obstruction.

Dried orange peel：For rutaceae orange Citrus reticulata Blanco and its drying and ripening of variety fruit Skin.Medicinal material is divided into " dried orange peel " and " citrus chachiensis hortorum ".Harvesting ripe fruit, strips pericarp, dries or low temperature drying.It is bitter, pungent, temperature.Return Lung, the spleen channel.Function regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For chest gastral cavity turgor. deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.《Cure mainly secret wanting》Cloud is bitter Pungent beneficial gas, sharp lung has Radix Glycyrrhizae then tonifying lung, without then purging the lung of pathogenic fire.《Detailed outline》：" orange peel, hardship can rush down can it is dry, pungent energy dissipate, temperature can and.It is controlled All kinds of diseases and ailments, always take its qi-regulating and make an uproar wet work(, then mend with tonic, then rush down with cathartic, then rise with hydrargyrum oxydatum crudum, then drop with drop medicine.Spleen is unit The mother of gas, lung is the key for taking the photograph gas, therefore orange peel is the medicine of two Jing gas point.

Perilla seed：Taste is pungent, it is warm in nature.Return lung Jing.Indication sending down abnormally ascending dissolving phlegm, relievings asthma, ease constipation.For phlegm stops up the circulation of vital energy in the wrong direction, cough Asthma, dry constipation of intestines.《Do not record》：Main lower gas, in cold.《Haigoushen》：Your Majesty's gas is coughed inverse.Control wet wind knot in cold air and waist pin Gas.《Japan hanako materia medica》：In homophony, beneficial the five internal organs, lower gas, only cholera, vomiting, gastric disorder causing nausea, qi-restoratives labor, the strong people of fertilizer, sharp stool and urine is broken Crux, disappear five diaphragms, cough-relieving, embellish lung, eliminating phlegm-retention.《Amplification on Materia Medica》：Control lung qi and breathe heavily urgency.《Detailed outline》：Control wind pleasant, sharp diaphragm width Intestines, solving toxin of fish and crab.《Book on Chinese herbal medicine converges》：Perillaseed, scattered gas is very prompt, most can the upper and lower all gas of profit clearly, Dingchuan phlegm is active, and can lead to two just, removes Wind-cold-dampness arthralgia.It is unavailable if the deficiency of vital energy and fullness sensation in chest person, or with tonic and Shi Yike.《This Jing meets original》：Zhu Xiang is all dry, only perillaseed Solely profit, is the special medicine of cough due to consumptive disease.Gas under performance, thus the unfavorable person of chest diaphragm preferably it, Exocarpium Citri Rubrum be all cough except dihydroxypropyltheophylline, that dissolving phlegm is pleasant is good Agent.

Giant knotweed：Mildly bitter flavor, it is micro- cold in nature.Return liver, courage, lung channel.Indication expelling wind and removing dampness, scattered stasis pain is relieving cough and reducing sputum.With In joint pain, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum.The bitter drop of giant knotweed is let out Heat, and energy preventing phlegm from forming and stopping coughing, breath with cough for cough with lung heat, abundant expectoration, and this product also has the effect of laxative defaecation.

Fruit of negundo：For the fruit of Verbenaceae five-leaved chaste tree.Taste is pungent is bitter, warm in nature.Indication:Wind-dispelling, eliminating phlegm, promoting the circulation of qi, Pain relieving.Cure cold, cough, asthma, wandering arthritis, malaria, stomachache, hernia, anal fistula.《Yuhuan will》：Help digestion lower gas.《Guangzhou plant Will》：Wind-dispelling, wash phlegm, antibechic.《Nanning City's medicine will》：" temperature Jing dissipates the stasis of blood, expelling pathogenic factors from muscles by diaphoresis.Cure cold, malaria, asthma."《Sichuan Chinese medicinal herbal》：Nourishing the liver removes wind, promoting qi circulation and relieving pain.The hiccup due to cold-evil that cures the wound is inverse, cough and asthma, food stagnation, and herria and anal fistula life are managed.

Snakegourd Fruit：It is sweet, slight bitter, cold in nature.Return lung, stomach, large intestine channel.Indication：Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens moisturizes cunning Intestines.For cough with lung heat, the turbid Huang of phlegm is thick, and chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swells and ache, constipation.

The tuber of pinellia：Taste is pungent, it is warm in nature；It is poisonous.Returns spleen, stomach, lung channel.Indication：It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass. For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus；Life controlling outward carbuncle swells Subcutaneous nodule.Pinellia is used for stopping nausea and vomiting by lowering the adverse flow of QI.《This Jing》：Main typhoid fever fever and chills, hardness in the epigastrium, lower gas, laryngopharynx swells and ache, and a dizzy chest is swollen, coughs It is inverse, borborygmus, hidroschesis.《Do not record》：The full knot of trusted subordinate's chest diaphragm phlegm heat that disappears, cough with dyspnea, acute pain in the epigastrium heavily fortified point ruffian, when gas vomit it is inverse；Subduing inflammation, Induced abortion, treats impotence Huang, pleases pool appearance.《Haigoushen》：Dissolving phlegm saliva, Appetizing spleen-tonifying, anti-nausea goes phlegm in the heart to expire, and lower lung qi, master coughs Knot.New survivor painting carbuncle swells of rubbing do not disappear, and can remove knurl goitre.The deficiency of vital energy and have mental disorder, plus and use it.《Cure mainly secret wanting》Cloud, dry stomach is wet, changes Phlegm, Energy benefit taste gas, dispersing swelling and dissipating binds, except sputum in the heart.

The invention has the beneficial effects as follows：

The invention provides a kind of pharmaceutical composition for treating livestock and poultry cough and asthma, and it is theoretical there is provided Traditional Chinese Medicine animal doctor, Prepare under the prescription foundation of clearing lung and eliminating phlegm and control principle, it not only has good clearing lung and eliminating phlegm, drying damp and strengthening spleen, width The effects such as chest dissipating bind, but also with clinical efficacy it is obvious, side effect is low, noresidue, be not likely to produce drug resistance, it is with low cost, Easy to use the features such as, for livestock and poultry cough and asthma has good prevention and treatment effect.Using this kind of compound Chinese medicinal preparation in rule Modelling can reduce livestock and poultry cough and asthma number of times during cultivating, improve feed intake, whet the appetite, and can promote in large-scale cultivation factory Using.Relieving cough and asthma effect of its medicine is extremely notable, and to animal subject be it is safe, reliably.

Specific embodiment

Based on the embodiment in the present invention, those of ordinary skill in the art are obtained under the premise of creative work is not made The every other embodiment for obtaining, belongs to the scope of protection of the invention.

Embodiment 1：

One kind improves feed intake, reduces the Chinese medicine compound prescription powder of cough and asthma number of times, including：800 parts of snow pears (fresh), 100 part hundred Conjunction, 30 parts of balloonflower roots, 25 parts of dried orange peels, 30 parts of perilla seeds, 35 parts of giant knotweeds, 25 parts of fruits of negundo, 25 parts of prepared RHIZOMA PINELLIZE without adju-vant, 35 parts of Snakegourd Fruits

Its concrete preparation method is as follows：

1) the fresh snow pear of recipe quantity is weighed, snow pear juice is squeezed to obtain, it is standby；It is snow pear residue and the lily of recipe quantity, balloonflower root, old Skin, perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight measures water for 10-12 times or the alcohol reflux of 50%-60% is carried Take 2 times, each 1-2 hours.Filter, merge extract and snow pear juice, be evaporated to relative density 1.20-1.28 (50 DEG C), Drying under reduced pressure is into dry cream；

Embodiment 2：

One kind improves feed intake, reduces the Chinese medicine compound prescription powder of cough and asthma number of times, including：850 parts of snow pears (fresh), 120 part hundred Conjunction, 35 parts of balloonflower roots, 30 parts of dried orange peels, 35 parts of perilla seeds, 40 parts of giant knotweeds, 30 parts of fruits of negundo, 30 parts of prepared RHIZOMA PINELLIZE without adju-vant, 40 parts of Snakegourd Fruits

Its concrete preparation method is as follows：

Embodiment 3：

One kind improves feed intake, reduces the Chinese medicine compound prescription powder of cough and asthma number of times, including：750 parts of snow pears (fresh), 80 part hundred Conjunction, 25 parts of balloonflower roots, 20 parts of dried orange peels, 25 parts of perilla seeds, 30 parts of giant knotweeds, 20 parts of fruits of negundo, 25 parts of prepared RHIZOMA PINELLIZE without adju-vant, 30 parts of Snakegourd Fruits

Embodiment 4：

One kind improves feed intake, reduces the Chinese medicine compound prescription powder of cough and asthma number of times, including：750-850 part snow pears (fresh), 80- 120 parts of lilies, 25-35 part balloonflower roots, 20-30 part dried orange peels, 25-35 part perilla seeds, 30-40 part giant knotweeds, 20-30 part fruits of negundo, 25- 30 parts of prepared RHIZOMA PINELLIZE without adju-vant, 30-40 part Snakegourd Fruits.

Its concrete preparation method is as follows：

The beneficial effect of the Chinese medicine compound prescription that the present invention relievings asthma is illustrated below by way of concrete test example.

Test example 1

1 materials and methods

1.1 trial drugs

Test drug：Scattered, embodiment 1 prepared by embodiment 1 lacks the scattered and embodiment 1 of monarch drug in a prescription preparation and lacks dissipating for ministerial drug preparation Chinese medicine compound prescription of the invention by please the people peace (Beijing) development in science and technology Co., Ltd provide.

Control medicine：Datura flower asthma relieving powder

1.2 experimental animals

The Landrace of 5.5 kilograms or so of 23 age in days provided for Beijing Hui Chuanzhaoliang animal husbandry Co., Ltd and the two of Large White First hybridized pig.Totally 160 pigs, are randomly divided into four groups, and 40 per group, experimental group 1 is dissipating for the preparation of embodiment 1, and experimental group 2 is real Apply example 1 and lack dissipating for monarch drug in a prescription preparation, experimental group 3 is that embodiment 1 lacks dissipating for ministerial drug preparation, and control group is controlled using datura flower asthma relieving powder Treat.Experimental group medicine is added respectively in the boiled water for putting temperature of 15ml in 7.5g medicines, after stirring evenly, is gavaged, and daily 2 times, is used in conjunction 7 My god.Control group is datura flower asthma relieving powder, 10g, spice, and one time a day, is used in conjunction 7 days.

Efficacy determination：

Recovery from illness：Jing is treated, and ill sucking pig spirit, appetite, breathing recover normal, and clinical symptoms are wholly absent.

Effectively：Jing is treated, and ill sucking pig spirit preferably, gradually recover by appetite, and a small amount of sucking pig has syndrome characterized by dyspnea sound, and clinical symptoms are delayed Solution.

It is invalid：Jing is treated, and, without improvement, cough and asthma is without improvement, aggravation or uses other drugs instead for ill piglet spirit, appetite Treatment, in addition it is dead.

1.3 experimental results：

1.3.1 weaned piglets change

Every repetition average weight gain is counted according to the situation of weighing of each repetition pig, 1 is the results are shown in Table.

Table 1 early stage weaned piglets/head, kg

Group	Starting weight	End weight	Daily gain (ADG)
				Experimental group 1	6.65±0.03	8.62±0.02	0.28
Experimental group 2	6.68±0.04	7.81±0.03	0.16
				Experimental group 3	6.56±0.04	8.03±0.04	0.21
Control group	6.73±0.02	7.81±0.03	0.15

As can be seen from Table 1, daily gain experimental group 1>3 groups of experimental group>Experimental group 2>Control group, it can be seen that, the present invention Chinese medicine compound prescription group of formula rationally, the feed intake of piglet can be improved.

1.3.1 piglet cough and asthma degree

The total effective rate of the medicine of experimental group 1 is 97.5%, and experimental group 2 is 17.5%, and experimental group 3 is 45.0%, control group For 85.0%, the total effective rate of experimental group 1 is apparently higher than other groups.The cure rate of the medicine of experimental group 1 is 95.0%, and experimental group 2 is 12.5%, experimental group 3 is 40.0%, and control group is 80.0%, and the cure rate of experimental group 1 is apparently higher than other groups.Illustrate the present invention Chinese medicine compound prescription group have preferable therapeutic action to pig cough and asthma, its therapeutic action to livestock and poultry cough and asthma is the results detailed in Table 1.

The cough and asthma degree treatment results of the sucking pig of table 1

1.4 conclusions：

Prevention piglet cough and asthma is the difficult point of aquaculture, and the result of this test shows, addition Chinese medicine compound prescription can improve feed intake, Cough and asthma number of times is significantly reduced, makes cough and asthma symptom disappear, relieving cough and asthma effect of its medicine is extremely notable, and is to animal subject Safety, reliably.

Test example 2

Clinical trial animal selects 3 week old chickens, and clinical symptoms are decreased obviously for feed intake, spiritual depressed, unilateral or bilateral Nasal sinus, eyelid swelled, appetite is remarkably decreased, and gets rid of head, coughs, sneezes, expiratory dyspnea.The isolation of ill chicken is individually raised, is raised Complete feed is fed, and is randomly divided into 5 groups, 100 per group, 5 groups of feeding environments are identical, and experimental period is carried out altogether 5 days；It is blank Control group is left intact, and control drug used by positive controls " Maxingshigan oral liquid " is used according to an instruction treatment, 1,2,3 groups of experimental group is consistent with test example 1, day dose be：Per 100g present composition spices 1kg feedings, daily 1-2 It is secondary；The purpose for the treatment of disease is reached after oral by gastrointestinal absorption.Computational methods：The death rate=dead animal number/test is moved Thing number × 100%, cure rate=healing number of animals/experimental animal number × 100%.Following table is the result at the end of experiment.

Efficacy assessment standard：

It is invalid：Spirit is highly depressed, drives to walk, and appetite is remarkably decreased, and gets rid of head, coughs, sneezes, tracheae rale.Cut open Visible annulus trachealis hyperemia, bleeding are examined, there is more serosity, Catarrhal and cheesy exudate；Visible bleeding in lung's bronchus, Kidney uric acid mineralization.It is inefficiency that invalid chicken number accounts for the percentage of this group of chicken number.

Effectively：Spiritual preferable, appetite is gradually recovered, and a small amount of chicken gets rid of head, coughs, sneezes.Cut open inspection observes visible tracheae A small amount of serosity and Catarrhal mucus, annulus trachealis is slight congested, rubescent, and kidney lithate is deposited on a small quantity.Effectively chicken number accounts for this The percentage of group chicken number is efficient.

Recovery from illness：Spirit, appetite, breathing recover normal, the tissue no abnormality seen such as cut open inspection trachea-bronchial epithelial cell, lungs, kidney. It is cure rate that recovery from illness chicken number accounts for the percentage of this group of chicken number.

Total effective rate：The percentage of this group of chicken number is effectively accounted for recovery from illness chicken number summation.

Table 2 is the situation contrast that the present invention and other medicines treat chicken respiratory tract disease

This clinical effectiveness statistical analysis, experimental group of the present invention 1 and numb apricot stone glucoside oral liquid group phase in terms of cure rate Compare indifference, hence it is evident that better than experimental group 2 and experimental group 3.The present invention is found surprisingly that the collocation of each component of the present invention has collaboration Synergistic effect.

Claims

1. a kind of Chinese medicine composition for treating livestock and poultry cough illness, it is characterised in that its by following weight proportioning Chinese medicine material medicine system Standby：600-1000 part snow pears (fresh), 60-140 part lilies, 10-60 part balloonflower roots, 10-40 part dried orange peels, 10-50 part purple perillas Son, 10-60 part giant knotweeds, 10-40 part fruits of negundo, 10-40 part prepared RHIZOMA PINELLIZE without adju-vant, 10-60 part Snakegourd Fruits.

2. it is according to claim 1 treatment livestock and poultry cough illness Chinese medicine composition, it is characterised in that it is matched somebody with somebody by following weight What the Chinese medicine material medicine of ratio was prepared from：700-900 part snow pears (fresh), 70-130 part lilies, 20-40 part balloonflower roots, 15-35 parts are old Skin, 20-40 part perilla seeds, 20-50 part giant knotweeds, 15-35 part fruits of negundo, 15-35 part prepared RHIZOMA PINELLIZE without adju-vant, 20-50 part Snakegourd Fruits.

3. it is according to claim 1 treatment livestock and poultry cough illness Chinese medicine composition, it is characterised in that it is matched somebody with somebody by following weight What the Chinese medicine material medicine of ratio was prepared from：800 parts of snow pears (fresh), 100 parts of lilies, 30 parts of balloonflower roots, 25 parts of dried orange peels, 30 parts of purple perillas Son, 35 parts of giant knotweeds, 25 parts of fruits of negundo, 25 parts of prepared RHIZOMA PINELLIZE without adju-vant, 35 parts of Snakegourd Fruits.

4. it is according to claim 1 treatment livestock and poultry cough illness Chinese medicine composition, it is characterised in that：The Chinese medicine composition For powder, capsule, oral liquid, granule, pill or tablet.

5., according to the preparation method of the arbitrary described Chinese medicine composition for treating livestock and poultry cough illness of claim 1-4, its feature exists It is as follows in step：

1) the fresh snow pear of recipe quantity is weighed, snow pear juice is squeezed to obtain, it is standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, Perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight extracts 2-3 for the 8-15 times of alcohol reflux for measuring water or 40%-70% Secondary, each 1-2 hours are filtered, and merge extract and snow pear juice, are evaporated to relative density 1.20-1.28 (50 DEG C), decompression It is dried to dry cream；

2) dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mixed, prepare capsule, powder, granule or piece Agent.

6. it is according to claim 5 treatment livestock and poultry cough illness Chinese medicine composition preparation method, it is characterised in that：Step 1) in, the fresh snow pear of recipe quantity is weighed, squeezes to obtain snow pear juice, it is standby；Lily, balloonflower root, dried orange peel, the purple of snow pear residue and recipe quantity Perillaseed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight is extracted 2 times for the 10-12 times of alcohol reflux for measuring water or 50%-60%, Each 1-2 hours.

7. a kind of Chinese medicine composition according to claim 1 is in the medicine for treating or preventing livestock and poultry cough illness is prepared Application.