CN106421331A

CN106421331A - Traditional Chinese medicine composition for treating livestock and poultry cough with asthma and preparation method thereof

Info

Publication number: CN106421331A
Application number: CN201611002482.XA
Authority: CN
Inventors: 牛卫宁; 梁冰; 尹朋
Original assignee: Most Cas (beijing) Technology Development Co Ltd
Current assignee: Most Cas (beijing) Technology Development Co Ltd
Priority date: 2016-11-15
Filing date: 2016-11-15
Publication date: 2017-02-22

Abstract

The invention provides a traditional Chinese medicine composition for treating livestock and poultry cough with asthma, characterized by being prepared from snow pear (fresh), lily bulb, Radix Platycodi, dried tangerine peel, Fructus Perillae, Rhizoma Polygoni Cuspidati, Fructus Viticis, Rhizoma Pinelliae Preparata, and Fructus Trichosanthis. By using the traditional Chinese medicine compound preparation in large-scale pig farming, suckling pigs suffer less cough with asthma, feed intake is increased, appetite is enhanced, and the composition is suitable for popularization and application in large-scale pig farms.

Description

A kind of Chinese medicine composition treating livestock and poultry cough illness and preparation method thereof

Technical field

The invention belongs to Chinese medicine compound prescription field, it is related to a kind of Chinese medicine composition treating livestock and poultry cough illness and its preparation side Method.

Background technology

Pig cough illness is to be caused a kind of chronic respiratory tract disease of pig by mycoplasma hyopneumoniae, is pig endemicity lung again Inflammation, is a kind of chronic lung disease of pig, and main clinic symptoms are coughs and pant.Cardinal symptom is cough, asthma.The sick initial stage is short Promote, dry cough, flow out a small amount of serosity nose liquid simultaneously, stream canescence mucus or purulence nose liquid when seriously ill, it is existing that asthma in mid-term As.Body temperature normally, appetite no significant change.Sick stage asthma increases, and dehisces to breathe, lassitude, and pig body is become thin, no Hope is walked about.

Pig cough illness is most commonly seen with autumn and winter, and different cultivars, the pig at age all can infect.Sucking pig is to be easiest to infect, Next to that milking sow, being in chronic process or subclinical infection Adult Pig more.The incidence of disease of pig cough and asthma is higher, and after morbidity, feed-weight ratio increases Plus, poor growth, feed consumption rate also showed increased, cause feeding cost to increase, economic loss is serious.Therefore, it is badly in need of a kind of high treatment Effect, the Chinese medical extract of the preventing and treating piglet cough and asthma of low-residual, can effectively reduce cough and asthma, significantly reduce the morbidity of porcine respiratory disease Rate.

Content of the invention

It is an object of the invention to provide a kind of highly effective and safe, the Chinese medicine composition improving feed intake, treating livestock and poultry cough illness And preparation method thereof.

To achieve these goals, the technical solution adopted in the present invention is as follows：

A kind of Chinese medicine composition treating livestock and poultry cough illness it is characterised in that this Chinese medicine composition by following parts by weight raw material Medicine is prepared from：The fresh snow pear of 600-1000 part, 60-140 part lily, 10-60 part balloonflower root, 10-40 part dried orange peel, 10-50 part are purple Perillaseed, 10-60 part giant knotweed, 10-40 part fruit of negundo, 10-40 part prepared RHIZOMA PINELLIZE without adju-vant, 10-60 part Snakegourd Fruit.

Further, the Chinese medicine composition of described treatment livestock and poultry cough illness is it is characterised in that it is by following weight proportioning Bulk drug be prepared from：The fresh snow pear of 700-900 part, 70-130 part lily, 20-40 part balloonflower root, 15-35 part dried orange peel, 20-40 Part perilla seed, 20-50 part giant knotweed, 15-35 part fruit of negundo, 15-35 part prepared RHIZOMA PINELLIZE without adju-vant, 20-50 part Snakegourd Fruit.

Further, the Chinese medicine composition of described treatment livestock and poultry cough illness is it is characterised in that it is joined by following weight The bulk drug of ratio is prepared from：The fresh snow pear of 750-850 part, 80-120 part lily, 25-35 part balloonflower root, 20-30 part dried orange peel, 25- 35 parts of perilla seeds, 30-40 part giant knotweed, 20-30 part fruit of negundo, 25-30 part prepared RHIZOMA PINELLIZE without adju-vant, 30-40 part Snakegourd Fruits.

Further, described treatment livestock and poultry cough illness Chinese medicine composition it is characterised in that：Described Chinese medicine composition is Powder, capsule, oral liquid, granule, pill or tablet.

Present invention also offers the preparation method of the described Chinese medicine composition for the treatment of livestock and poultry cough illness is it is characterised in that walk Suddenly as follows：

1）Weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, Perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight is the alcohol reflux extraction 2-3 of 8-15 times amount water or 40%-70% Secondary, each 1-2 hour, filters, merges extract and snow pear juice, be evaporated to relative density 1.20-1.28（50℃）, decompression It is dried to dry cream；

2）Dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mix, prepare capsule, powder, granule or piece Agent.

Preferably, step 1）In, weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；Snow pear residue and recipe quantity Lily, balloonflower root, dried orange peel, perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight be 10-12 times amount water or 50%-60% Alcohol reflux extract 2 times, each 1-2 hour.

The present invention also provide Chinese medicine composition described in example preparation for treat or prevent livestock and poultry cough illness medicine in Application.

Medicine composition and analysis：

Snow pear（Fresh）：Snow pear, pears name, meat tenderness Bai Ruxue, therefore claim, it is a kind of common fruit.Sweet cold in nature, tool fluid dryness, The effect of clearing heat and eliminating phlegm, nourishing blood and promoting granulation, it is particularly suitable for autumn edible.According to《Compendium of Materia Medica》Record, " its property is descending for pears person, profit Fluently." it is medicinal to control wind-heat, moistening lung, the cool heart, dissolving phlegm, fall fire, removing toxic substances.Medical research proves, pears truly have moistening lung dry clearly, only Cough the effect of resolving sputum, nourishing blood and promoting granulation.The throat therefore patient of acute tracheitis and the infection of the upper respiratory tract being occurred does, itches, bitterly, Sound is mute, phlegm is thick, constipation, the red, eliminating the phlegm of urine all have good effect.Bright Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica fruit two pears》:Newborn pears are avenged Pears ... can be cured the disease.

Lily：For liliaceous plant tiger lily Lilium lancifolium Thunb., lily Lilium brownii F.E.Brown var.viridulum Baker or the dry meat scale leaf of Lilium tenuifolium Lilium Pumilum DC..Autumn Excavation, cleans, strips scale leaf, put slightly boiling hot in boiling water, is dried.Sweet, tremble with fear.The thoughts of returning home, lung channel.Function Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.With In yin chronic cough, blood-stained sputum, dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded.《Sheng Nong's herbal classic》：Sweet, put down.Cure mainly perverse trend Abdominal distension, pained, sharp stool, urine, tonifying middle-Jiao and Qi.《Haigoushen》：Make, slightly poisonous.Main hundred evil ghosts and goblins, weep more than, except epigastric oppression Full pain, control tinea pedis heat cough inverse.

Balloonflower root：For Campanulaceae balloonflower root Platycodon grandiflorum（Jacq.）The dry root of A DC..Spring, Qiu Erji excavate, clean, remove fibrous root, take advantage of fresh peel off crust or do not remove crust, be dried.Bitter, pungent, put down.Return lung warp.Function is declared Lung, profit pharynx, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, and sore purulence becomes not burst.《Not Record》：Sharp the five internal organs stomach, replenishing blood and vital energy, except fever and chills, wandering arthritis, middle benefit gas disappear paddy, treat laryngopharynx pain.《Haigoushen》：Control diarrhea, blood-breaking, go to amass Gas, disappear accumulation, sputum, main lung heat shortness of breath cough inverse, except crymodynia in abdomen, main in dislike and pediatric epilepsy scared.《Amplification on Materia Medica》：Control lung carbuncle. 《Pearl sac》：Treat sore-throat, sharp lung qi, control nasal obstruction.

Dried orange peel：Drying and ripening fruit for rutaceae orange Citrus reticulata Blanco and its variety Skin.Medicinal material is divided into " dried orange peel " and " citrus chachiensis hortorum ".Harvesting ripe fruit, strips pericarp, dries or low temperature drying.Bitter, pungent, temperature.Return Lung, the spleen channel.Function regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For chest gastral cavity turgor. deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.《Cure mainly secret wanting》Cloud is bitter Pungent beneficial gas, sharp lung, there are Radix Glycyrrhizae then tonifying lung, no then purging the lung of pathogenic fire.《Detailed outline》：" orange peel, hardship can rush down can dry, pungent energy dissipate, temperature can and.It is controlled All kinds of diseases and ailments, always take its qi-regulating to make an uproar wet work(, then mend with tonic, then rush down with cathartic, then rise with hydrargyrum oxydatum crudum, then drop with fall medicine.Spleen is unit The mother of gas, lung is the key taking the photograph gas, therefore orange peel is two medicines dividing through gas.

Perilla seed：Taste is pungent, warm in nature.Return lung warp.Indication sending down abnormally ascending dissolving phlegm, relievings asthma, ease constipation.For phlegm stops up the circulation of vital energy in the wrong direction, cough Asthma, dry constipation of intestines.《Do not record》：Main lower gas, in cold.《Haigoushen》：Your Majesty's gas is coughed inverse.Control wet wind knot in cold air and waist pin Gas.《Japan hanako materia medica》：In homophony, beneficial the five internal organs, lower gas, only cholera, vomiting, gastric disorder causing nausea, qi-restoratives labor, fertile strong people, sharp stool and urine, break Crux, disappear five diaphragms, cough-relieving, embellish lung, eliminating phlegm-retention.《Amplification on Materia Medica》：Control lung qi and breathe heavily urgency.《Detailed outline》：Control wind pleasant, sharp diaphragm width Intestines, solving toxin of fish and crab.《Book on Chinese herbal medicine converges》：Perillaseed, scattered gas is very prompt, can profit all gas up and down clearly, Dingchuan phlegm is active, and can lead to two just, removes Wind-cold-dampness arthralgia.If the deficiency of vital energy and fullness sensation in chest person, unavailable, or with tonic and Shi Yike.《This is former through meeting》：Zhu Xiang is all dry, only perillaseed Solely moisten, be the special medicine of cough due to consumptive disease.Gas under performance, thus the unfavorable person of chest diaphragm preferably it, Exocarpium Citri Rubrum be all cough except dihydroxypropyltheophylline, that dissolving phlegm is pleasant is good Agent.

Giant knotweed：Mildly bitter flavor, micro- cold in nature.Return liver, courage, lung channel.Indication expelling wind and removing dampness, scattered stasis pain, relieving cough and reducing sputum.With In joint pain, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum.The bitter fall of giant knotweed is let out Heat, and energy preventing phlegm from forming and stopping coughing, breath with cough for cough with lung heat, abundant expectoration, this product also has the effect of laxative defaecation.

Fruit of negundo：Fruit for Verbenaceae five-leaved chaste tree.Taste is pungent is bitter, warm in nature.Indication:Wind-dispelling, eliminating phlegm, promoting the circulation of qi, Pain relieving.Cure cold, cough, asthma, wandering arthritis, malaria, stomachache, hernia, anal fistula.《Yuhuan will》：Help digestion lower gas.《Guangzhou plant Will》：Wind-dispelling, wash phlegm, antibechic.《Nanning City's medicine will》：" temperature is through dissipating the stasis of blood, expelling pathogenic factors from muscles by diaphoresis.Cure cold, malaria, asthma."《Sichuan Chinese medicinal herbal》：Nourishing the liver removes wind, promoting qi circulation and relieving pain.The hiccup due to cold-evil that cures the wound is inverse, cough and asthma, food stagnation, and herria and anal fistula life are managed.

Snakegourd Fruit：Sweet, slight bitter, cold in nature.Return lung, stomach, large intestine channel.Indication：Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize cunning Intestines.For cough with lung heat, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, and acute appendicitis swells and ache, constipation.

The tuber of pinellia：Taste is pungent, warm in nature；Poisonous.Returns spleen, stomach, lung channel.Indication：Eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass. For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus；Life controlling outward carbuncle swells Subcutaneous nodule.Pinellia is used for stopping nausea and vomiting by lowering the adverse flow of QI.《This warp》：Main typhoid fever fever and chills, hardness in the epigastrium, lower gas, laryngopharynx swells and ache, and a dizzy chest is swollen, coughs Inverse, borborygmus, hidroschesis.《Do not record》：Disappearing, trusted subordinate's chest diaphragm phlegm heat is full to be tied, cough with dyspnea, acute pain in the epigastrium heavily fortified point ruffian, when gas vomit inverse；Subduing inflammation, Induced abortion, treats impotence Huang, pleases pool appearance.《Haigoushen》：Dissolving phlegm saliva, Appetizing spleen-tonifying, anti-nausea, go phlegm in the heart full, lower lung qi, master coughs Knot.New survivor painting carbuncle swells of rubbing do not disappear, and can remove knurl goitre.The deficiency of vital energy and have mental disorder, plus and use it.《Cure mainly secret wanting》Cloud, dry stomach is wet, changes Phlegm, Energy benefit taste gas, dispersing swelling and dissipating binds, except sputum in the heart.

The invention has the beneficial effects as follows：

The invention provides a kind of pharmaceutical composition treating livestock and poultry cough and asthma, and it is theoretical, in clearing lung-heat to provide Traditional Chinese Medicine animal doctor Prepare under the prescription foundation of resolving sputum and control principle, it not only has good clearing lung and eliminating phlegm, drying damp and strengthening spleen, wide chest dissipates The effects such as knot, but also have that clinical efficacy is obvious, side effect is low, noresidue, be not likely to produce drug resistance, with low cost, use The features such as facilitate, has good prevention and treatment effect for livestock and poultry cough and asthma.Using this kind of compound Chinese medicinal preparation in scale Livestock and poultry cough and asthma number of times can be reduced during cultivation, improve feed intake, whet the appetite, can promote in large-scale cultivation factory should With.Relieving cough and asthma effect of its medicine is extremely notable, and is safe to animal subject, reliably.

Specific embodiment

Based on the embodiment in the present invention, those of ordinary skill in the art are obtained under the premise of not making creative work The every other embodiment obtaining, broadly falls into the scope of protection of the invention.

Embodiment 1：

A kind of Chinese medicine compound prescription powder improving feed intake, reducing cough and asthma number of times, including：800g snow pear（Fresh）, 100g lily, 30g Balloonflower root, 25g dried orange peel, 30g perilla seed, 35g giant knotweed, 25g fruit of negundo, 25g prepared RHIZOMA PINELLIZE without adju-vant, 35g Snakegourd Fruit.Its concrete preparation method is such as Under：

1）Weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, Perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight is boiled 3 times for 12 times amount decoctings, 2 hours every time, filters, merging carries Take liquid and snow pear juice, be evaporated to relative density 1.25（50℃）, drying under reduced pressure become dry cream；

2）Dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mix, dry, pulverize, filling, obtain final product powder 200g.

Embodiment 2：

A kind of Chinese native medicine compound prescription pellet agent improving feed intake, reducing cough and asthma number of times, including：4000g snow pear（Fresh）, 560g lily, 240g balloonflower root, 160g dried orange peel, 200g perilla seed, 240g giant knotweed, 160g fruit of negundo, 160g prepared RHIZOMA PINELLIZE without adju-vant, 240g Snakegourd Fruit.It is specifically made Preparation Method is as follows：

Weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, purple Perillaseed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight be 10 times amount 60% alcohol reflux extract 2 times, 1 hour every time, mistake Filter, merges extract and is evaporated to no alcohol taste, adds snow pear juice to be evaporated to relative density 1.20（50℃）, vacuum drying Become dry cream, pulverize, cross 100 mesh sieves, add appropriate amount of auxiliary materials, plus appropriate amount of ethanol is pelletized, and prepares granule 1000g.

Embodiment 3：

A kind of Chinese medicine compound prescription powder improving feed intake, reducing cough and asthma number of times：Weigh each bulk drug, 600 parts of snow by following weight Pears（Fresh）, 60 portions of lilies, 10 parts of balloonflower root, 10 parts of dried orange peels, 10 parts of perilla seeds, 10 parts of giant knotweeds, 10 parts of fruits of negundo, 10 parts of prepared RHIZOMA PINELLIZE without adju-vant, 10 parts of Snakegourd Fruits.Its concrete preparation method is as follows：

1）Weigh the snow pear of recipe quantity（Fresh）, it is dried；

2）Weigh the lily of recipe quantity, balloonflower root, dried orange peel, perilla seed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, with dried snow Pears, mixing, after pulverizing, cross 80 mesh sieves, packing, obtain final product.

Embodiment 4：

A kind of Chinese medicine compound prescription tablet improving feed intake, reducing cough and asthma number of times, including：1800g snow pear（Fresh）, 140g lily, 40g Balloonflower root, 40g dried orange peel, 40g perilla seed, 40g giant knotweed, 30g fruit of negundo, 30g prepared RHIZOMA PINELLIZE without adju-vant, 40g Snakegourd Fruit.Its concrete preparation method is such as Under：

Weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, purple Perillaseed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, add weight be 10 times amount 50% alcohol reflux extract 2 times, 1.5 hours every time, Filter, merge extract and be evaporated to no alcohol taste, add snow pear juice to be evaporated to relative density 1.25（50℃）, vacuum do Dry one-tenth dry cream, pulverizes, and crosses 100 mesh sieves, adds appropriate amount of auxiliary materials, plus appropriate amount of ethanol is pelletized, compressing tablet, prepares 1000, tablet, 0.4g/ Piece.

The beneficial effect of the Chinese medicine compound prescription that the present invention relievings asthma is described below by way of concrete test example.

Test example 1

1 materials and methods

1.1 trial drug

Test drug：The Chinese medicine compound prescription of the present invention of embodiment 1 and embodiment 2 by happy people's peace（Beijing）The limited public affairs of development in science and technology Department provides.

Comparison medicine：Datura flower asthma relieving powder for animals

1.2 experimental animal

The Landrace of 2.5 kilograms about of 5 age in days providing for Beijing herding company and the bi-crossbreeding of Large White.Totally 120 Head pig, is randomly divided into three groups, every group 40, is treated using preparation embodiment 1 and embodiment 2 and control drug respectively.System Standby embodiment 1 or 2 medicines, in 30g medicine, addition 60ml is boiled puts in warm water, after stirring evenly, gavages, daily 2 times, is used in conjunction 7 My god.Control group is datura flower asthma relieving powder for animals, 30g, spice, and one time a day, is used in conjunction 7 days.

Efficacy determination：

Recovery from illness：Through treatment, ill sucking pig spirit, appetite, breathing recover normal, and clinical symptoms are wholly absent.

Effectively：Through treatment, ill sucking pig spirit preferably, gradually recover, and a small amount of sucking pig has syndrome characterized by dyspnea sound, and clinical symptoms are delayed by appetite Solution.

Invalid：Through treatment, ill sucking pig spirit, appetite no take a turn for the better, and cough and asthma no takes a turn for the better, aggravation or use other drugs instead Treatment, in addition dead.

1.3 experimental result：

1.3.1 sucking pig production performance changes

Every repetition average weight gain is counted according to the situation of weighing that each repeats pig, the results are shown in Table 1.

Table 1 early stage sucking pig production performance/head, kg

Group	Starting weight	End weight	Daily gain（ADG）
				Treatment group 1	2.58±0.02	4.12±0.04	0.22
Treatment group 2	2.75±0.05	4.22±0.05	0.21
				Control group	2.62±0.01	3.67±0.02	0.15

As can be seen from Table 1, the 2 groups of daily gains for the treatment of group 1 and treatment group adding Chinese medicine compound prescription are higher than control group, thus may be used See, the Chinese medicine compound prescription adding the present invention can improve the feed intake of sucking pig.

1.3.1 sucking pig cough and asthma degree

The total effective rate of embodiment 1 medicine and experimental example 2 medicine is respectively 97.5% and 95.0%, and control group is 90.0%, test group Compare with control group, test group is higher than control group.The cure rate of embodiment 1 medicine and embodiment 2 medicine is respectively 75.05% He 72.%, control group is 60.0%, and test group is compared with control group, and cure rate is significantly raised, illustrates that this medicine has preferably to pig cough and asthma Therapeutic action, it is to the therapeutic action of livestock and poultry cough and asthma the results detailed in Table 1.

The cough and asthma degree treatment results of table 1 sucking pig

Group	Number of cases	Recovery from illness	Effectively	Invalid	Efficient %
						Treatment group 1	40	30	9	1	97.5%
Treatment group 2	40	29	9	2	95.0%
						Control group	30	18	9	3	90.0%

1.4 conclusion：

Prevention sucking pig cough and asthma is the difficult point of aquaculture, and the result of this test shows, adds Chinese medicine compound prescription and can improve feed intake, significantly Reduce cough and asthma number of times, so that cough and asthma symptom is disappeared, relieving cough and asthma effect of its medicine is extremely notable, and is safety to animal subject , reliably.

Claims

1. a kind of Chinese medicine composition treating livestock and poultry cough illness is it is characterised in that it is by the bulk drug preparation of following weight proportioning Become：600-1000 part snow pear（Fresh）, 60-140 part lily, 10-60 part balloonflower root, 10-40 part dried orange peel, 10-50 part perilla seed, 10-60 part giant knotweed, 10-40 part fruit of negundo, 10-40 part prepared RHIZOMA PINELLIZE without adju-vant, 10-60 part Snakegourd Fruit.

2. the Chinese medicine composition for the treatment of livestock and poultry cough illness according to claim 1 is it is characterised in that it is joined by following weight The bulk drug of ratio is prepared from：700-900 part snow pear（Fresh）, 70-130 part lily, 20-40 part balloonflower root, 15-35 part dried orange peel, 20-40 part perilla seed, 20-50 part giant knotweed, 15-35 part fruit of negundo, 15-35 part prepared RHIZOMA PINELLIZE without adju-vant, 20-50 part Snakegourd Fruit.

3. the Chinese medicine composition for the treatment of livestock and poultry cough illness according to claim 1 is it is characterised in that it is joined by following weight The bulk drug of ratio is prepared from：750-850 part snow pear（Fresh）, 80-120 part lily, 25-35 part balloonflower root, 20-30 part dried orange peel, 25-35 part perilla seed, 30-40 part giant knotweed, 20-30 part fruit of negundo, 25-30 part prepared RHIZOMA PINELLIZE without adju-vant, 30-40 part Snakegourd Fruit.

4. according to claim 1 treatment livestock and poultry cough illness Chinese medicine composition it is characterised in that：Described Chinese medicine composition For powder, capsule, oral liquid, granule, pill or tablet.

5. the preparation method of the Chinese medicine composition according to the arbitrary described treatment livestock and poultry cough illness of claim 1-4, its feature exists As follows in step：

6. according to claim 5 treatment livestock and poultry cough illness Chinese medicine composition preparation method it is characterised in that：Step 1）In, weigh the fresh snow pear of recipe quantity, squeeze to obtain snow pear juice, standby；The lily of snow pear residue and recipe quantity, balloonflower root, dried orange peel, purple Perillaseed, giant knotweed, fruit of negundo, prepared RHIZOMA PINELLIZE without adju-vant, Snakegourd Fruit, the alcohol reflux extraction for 10-12 times amount water or 50%-60% for the add weight 2 times, often Secondary 1-2 hour.

7. a kind of Chinese medicine composition according to claim 1 preparation for treat or prevent livestock and poultry cough illness medicine in Application.