CN110141557A - 氢化可的松控制释放制剂 - Google Patents

氢化可的松控制释放制剂 Download PDF

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Publication number
CN110141557A
CN110141557A CN201910452557.1A CN201910452557A CN110141557A CN 110141557 A CN110141557 A CN 110141557A CN 201910452557 A CN201910452557 A CN 201910452557A CN 110141557 A CN110141557 A CN 110141557A
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CN
China
Prior art keywords
hydrocortisone
purposes
composition
pharmaceutical composition
adrenal
Prior art date
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Pending
Application number
CN201910452557.1A
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English (en)
Chinese (zh)
Inventor
希珀·华单
理查德·罗斯
马丁·惠特克
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Immedica UK Ltd
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Diurnal Ltd
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Publication of CN110141557A publication Critical patent/CN110141557A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61P5/00—Drugs for disorders of the endocrine system
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Addiction (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201910452557.1A 2012-02-13 2013-02-12 氢化可的松控制释放制剂 Pending CN110141557A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB1202433.7A GB201202433D0 (en) 2012-02-13 2012-02-13 Controlled drug release
GB1202433.7 2012-02-13
US201261599704P 2012-02-16 2012-02-16
US61/599,704 2012-02-16
US201261600958P 2012-02-20 2012-02-20
US61/600,958 2012-02-20
CN201380008921.6A CN104105481A (zh) 2012-02-13 2013-02-12 氢化可的松控制释放制剂

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380008921.6A Division CN104105481A (zh) 2012-02-13 2013-02-12 氢化可的松控制释放制剂

Publications (1)

Publication Number Publication Date
CN110141557A true CN110141557A (zh) 2019-08-20

Family

ID=45930017

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201910452557.1A Pending CN110141557A (zh) 2012-02-13 2013-02-12 氢化可的松控制释放制剂
CN201380008921.6A Pending CN104105481A (zh) 2012-02-13 2013-02-12 氢化可的松控制释放制剂

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CN201380008921.6A Pending CN104105481A (zh) 2012-02-13 2013-02-12 氢化可的松控制释放制剂

Country Status (29)

Country Link
US (2) US9750704B2 (enExample)
EP (1) EP2814469B1 (enExample)
JP (1) JP6293678B2 (enExample)
KR (1) KR102023559B1 (enExample)
CN (2) CN110141557A (enExample)
AU (1) AU2013220139B2 (enExample)
BR (1) BR112014020008B1 (enExample)
CA (1) CA2864031C (enExample)
CY (1) CY1123202T1 (enExample)
DK (1) DK2814469T3 (enExample)
ES (1) ES2792069T3 (enExample)
GB (2) GB201202433D0 (enExample)
HK (1) HK1203824A1 (enExample)
HR (1) HRP20200780T1 (enExample)
HU (1) HUE048904T2 (enExample)
IL (2) IL234061B (enExample)
IN (1) IN2014DN06808A (enExample)
LT (1) LT2814469T (enExample)
ME (1) ME03742B (enExample)
MX (1) MX361407B (enExample)
NZ (2) NZ715616A (enExample)
PL (1) PL2814469T3 (enExample)
PT (1) PT2814469T (enExample)
RS (1) RS60346B1 (enExample)
RU (1) RU2619869C2 (enExample)
SI (1) SI2814469T1 (enExample)
SM (1) SMT202000286T1 (enExample)
WO (1) WO2013121184A1 (enExample)
ZA (1) ZA201508728B (enExample)

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FR3057775B1 (fr) * 2016-10-26 2018-11-02 Crossject Solution pharmaceutique d’hydrocortisone pour dispositif d’injection
KR101982287B1 (ko) * 2019-01-04 2019-05-24 (주)청아굿푸드 천연 추출물 함유 서방성 제제 및 그 제조방법
WO2022152863A1 (en) 2021-01-15 2022-07-21 Galventa Gmbh Pulsatile release caffeine formulation
MX2023012437A (es) * 2021-04-22 2023-11-07 Civi Biopharma Inc Administracion oral de oligonucleotidos.
US11904046B1 (en) 2022-11-14 2024-02-20 Eton Pharmaceuticals, Inc. Hydrocortisone oral liquid formulations
WO2025240605A1 (en) * 2024-05-15 2025-11-20 Neurocrine Biosciences, Inc. Combination treatment

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