CN109310702A - 用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒 - Google Patents

用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒 Download PDF

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CN109310702A
CN109310702A CN201780031000.XA CN201780031000A CN109310702A CN 109310702 A CN109310702 A CN 109310702A CN 201780031000 A CN201780031000 A CN 201780031000A CN 109310702 A CN109310702 A CN 109310702A
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ncp
lipid
cancer
nano
prodrug
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林文斌
段晓品
陈怀芷
韩文博
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University of Chicago
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University of Chicago
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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CN201780031000.XA 2016-05-20 2017-05-22 用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒 Pending CN109310702A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662339594P 2016-05-20 2016-05-20
US62/339,594 2016-05-20
PCT/US2017/033822 WO2017201528A1 (en) 2016-05-20 2017-05-22 Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof

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US (1) US11246877B2 (enExample)
EP (1) EP3439666A4 (enExample)
JP (2) JP7090034B2 (enExample)
CN (1) CN109310702A (enExample)
WO (1) WO2017201528A1 (enExample)

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CN110507613A (zh) * 2019-07-29 2019-11-29 苏州大学 一种脂质体制剂及其制备方法与应用
CN110862546A (zh) * 2019-10-12 2020-03-06 厦门大学 一种甲氨蝶呤金属配位聚合物及其制备方法和应用
CN111840228A (zh) * 2019-04-09 2020-10-30 中国科学院上海药物研究所 肿瘤免疫脂质体，其制备方法和用途
CN112022324A (zh) * 2019-06-03 2020-12-04 纳诺贝克特里公司 用于通过冷冻疗法治疗个体的身体部分的包含纳米颗粒的冷冻系统
CN112321615A (zh) * 2020-10-30 2021-02-05 华中科技大学 一种基于喜树碱的二聚体化合物、其制备和应用
CN113975392A (zh) * 2021-10-29 2022-01-28 成都大学 一种光动力介导抗肿瘤免疫应答的二氢青蒿素纳米制剂及其制备方法与应用
US11246877B2 (en) 2016-05-20 2022-02-15 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
CN114053223A (zh) * 2020-08-07 2022-02-18 中国科学院上海药物研究所 复合脂质体、其制备方法及用途
WO2022088679A1 (zh) * 2020-10-30 2022-05-05 华中科技大学 一种清除肿瘤干细胞的方法、抗癌药物、载药系统及其应用
CN114588268A (zh) * 2022-03-25 2022-06-07 清华大学 提高激活sting通路和抗肿瘤t细胞应答的方法
CN114983943A (zh) * 2022-06-16 2022-09-02 苏州卫生职业技术学院 一种青蒿琥酯纳米靶向制剂及其制备方法与应用
CN116249525A (zh) * 2020-08-21 2023-06-09 芝加哥大学 用于癌症疗法的含有多个可裂解前体药物的纳米颗粒
CN116963779A (zh) * 2020-09-02 2023-10-27 国立大学法人东京大学 癌症免疫微环境的调节物质及其预防、诊断或治疗
US11826426B2 (en) 2017-08-02 2023-11-28 The University Of Chicago Nanoscale metal-organic layers and metal-organic nanoplates for x-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
US11872311B2 (en) 2011-07-08 2024-01-16 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
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US20190314324A1 (en) 2018-04-13 2019-10-17 The University Of Chicago Combination of micheliolide derivatives or nanoparticles with ionizing radiation and checkpoint inhibitors for cancer therapy
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CN110872324B (zh) * 2018-08-29 2021-09-14 中国科学院上海药物研究所 奥沙利铂偶联前药、其制备方法及用途
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WO2020217472A1 (ja) * 2019-04-26 2020-10-29 株式会社Jimro 治療抵抗性がんの予防又は治療用の医薬組成物
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WO2021237209A1 (en) * 2020-05-22 2021-11-25 The University Of Chicago Metal-organic frameworks deliver small molecules and biomacromolecules for cancer immunotherapy
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