CN109260130A - A kind of children's mothproof toothpaste and preparation method thereof - Google Patents
A kind of children's mothproof toothpaste and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The invention discloses a kind of children's mothproof toothpastes to treat it as the process of brushing teeth is attached to decayed tooth facing by adding herb extract；Wherein Cortex Magnoliae Officinalis contains Cortex Magnoliae Officinalis alcohol, Cortex Magnoliae Officinalis alcohol has special, lasting myorelaxant effects and extremely strong antibacterial action, main cariogenic bacteria Streptococcus mutans in oral cavity etc. can be inhibited and be killed, mushroom contains lentinan body, it can inhibit intraoral pathogen growth, plaque is prevented to be formed, prevent saprodontia, Cortex Magnoliae Officinalis treatment decayed tooth can be cooperateed with, in addition mushroom also contains ergosterol, and ergosterol is through solar radiation, vitamin D can be transformed into, enhance human immunological competence, helps tooth growth, be further reduced the generation of saprodontia phenomenon；Betulin is natural inhibitor, is conducive to the health of tooth and gum, effectively prevent decayed tooth, gingivitis and periodontitis；And what is selected is all extract in natural Chinese medicinal herb, and it is nontoxic for children, children's torso will not be impacted when treating Pediatric Oral Emergency problem.
Description
Technical field
Present invention relates particularly to a kind of children's mothproof toothpastes and preparation method thereof.
Background technique
Decayed tooth, is being commonly called as saprodontia, is bacteriosis, can be with secondary pulpitis and periapical inflammation, or even can cause tooth
Slot bone and inflammation of jaws.It is such as not treated in time, lesion continues to develop, and forms cavity, destroys disappearance completely to corona eventually, develops
Final result be loss of tooth.Dental caries feature is disease incidence height, and distribution is wide.Be the main common disease in oral cavity and the mankind most
It is listed as the big keypoint control disease of the mankind three with tumour and cardiovascular disease by one of universal disease, the World Health Organization
Disease.Generally acknowledged etiology of dental caries theory is tetrad factor theory at present, mainly (refers to parasitic animal and plant including bacterium, oral environment, host
Including the parasitic organism thereon such as helminth, virus) and the time.Its basic point are as follows: cariogenicity sugar (especially sucrose
With purification carbohydrate) it is tightly attached at facing, the Acquired Pellicle formed by sialoprotein.This Acquired Pellicle is not only able to
It is firmly attached to facing, and there can be time enough to produce acid in bacterial plaque deep layer under preference temperature, tooth is invaded, makes
Demineralization, and destruction of organic material in turn generates cavity.It is directed to decayed tooth problem, occurs a variety of mothproof sound of baby talk cream on the market, but
It is most of these toothpaste is used for adult, for children, adult toothpaste moderate stimulation is too strong or may swallow and makes
Main body at the ingredient of children's torso discomfort, and current children's toothpaste ingredient is only subtracted accordingly based on adult toothpaste
Lack some ingredients that may cause children's torso damage, for example reduces the content of sodium fluoride, and the reduction of these effective components
The effect of children's toothpaste protection Pediatric Oral Emergency health can be weakened accordingly again.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of harmless to the body, mothproof sound of baby talk cream that suitable children use.
To solve the above-mentioned problems, the technical scheme is that
A kind of children's mothproof toothpaste, is made of the material of following weight: 20-36 parts of clam betel, sea-buckthorn 20-32
Part, 16-30 parts of betulin, 15-25 parts of mushroom, 10-20 parts of Cortex Magnoliae Officinalis, 9-17 parts of Chinese gall, 7-15 parts of rhizoma corydalis, galla turcica 7-
13 parts, 50-66 parts of sorbierite, 28-38 parts of eggshell, 9-13 parts of xylitol, 9-17 parts of Nisin, hydroxypropyl guar gum 5-11
Part, 7-11 parts of sodium lauroyl sarcosine and 36-50 parts of deionized water.
Further, children's mothproof toothpaste, is made of the material of following weight: 36 parts of clam betel, sea-buckthorn
20 parts, 16 parts of betulin, 15 parts of mushroom, 10 parts of Cortex Magnoliae Officinalis, 9 parts of Chinese gall, 7 parts of rhizoma corydalis, 7 parts of galla turcica, 50 parts of sorbierite,
28 parts of eggshell, 9 parts of xylitol, 9 parts of Nisin, 5 parts of hydroxypropyl guar gum, 7 parts of sodium lauroyl sarcosine and deionized water 36
Part.
Further, children's mothproof toothpaste, is made of the material of following weight: 20 parts of clam betel, sea-buckthorn
32 parts, 30 parts of betulin, 25 parts of mushroom, 20 parts of Cortex Magnoliae Officinalis, 17 parts of Chinese gall, 15 parts of rhizoma corydalis, 13 parts of galla turcica, sorbierite 66
Part, 38 parts of eggshell, 13 parts of xylitol, 17 parts of Nisin, 11 parts of hydroxypropyl guar gum, 11 parts of sodium lauroyl sarcosine and go from
50 parts of sub- water.
Further, children's mothproof toothpaste, is made of the material of following weight: 28 parts of clam betel, sea-buckthorn
26 parts, 23 parts of betulin, 20 parts of mushroom, 15 parts of Cortex Magnoliae Officinalis, 13 parts of Chinese gall, 11 parts of rhizoma corydalis, 10 parts of galla turcica, sorbierite 58
Part, 33 parts of eggshell, 11 parts of xylitol, 13 parts of Nisin, 8 parts of hydroxypropyl guar gum, 9 parts of sodium lauroyl sarcosine and deionization
43 parts of water.
Beneficial effects of the present invention: by add herb extract, make its with the process of brushing teeth be attached to decayed tooth facing into
Row treatment；Wherein contain Cortex Magnoliae Officinalis alcohol in Cortex Magnoliae Officinalis extract, Cortex Magnoliae Officinalis alcohol has special, lasting myorelaxant effects and extremely strong
Antibacterial action can be inhibited and be killed to main cariogenic bacteria Streptococcus mutans in oral cavity etc., and mushroom contains lentinan body, energy
Inhibit intraoral pathogen growth, prevent plaque from being formed, prevent saprodontia, Cortex Magnoliae Officinalis inhibition and killing oral cavity can be cooperateed with mainly cariogenic
Bacterium, in addition mushroom also contains ergosterol, and ergosterol can be transformed into vitamin D through solar radiation, enhance human immunological competence,
Tooth growth is helped, the generation of saprodontia phenomenon is further reduced；Betulin is natural inhibitor, is conducive to tooth and gum
Health effectively prevent decayed tooth, gingivitis and periodontitis；And what is selected is all extract in natural Chinese medicinal herb, for children
It is nontoxic, children's torso will not be impacted when treating Pediatric Oral Emergency problem.
Specific implementation method
Embodiment 1
A kind of children's mothproof toothpaste, is made of the material of following weight: 36 parts of clam betel, 20 parts of sea-buckthorn, white birch
16 parts of lipidol, 15 parts of mushroom, 10 parts of Cortex Magnoliae Officinalis, 9 parts of Chinese gall, 7 parts of rhizoma corydalis, 7 parts of galla turcica, 50 parts of sorbierite, 28 parts of eggshell,
9 parts of xylitol, 9 parts of Nisin, 5 parts of hydroxypropyl guar gum, 7 parts of sodium lauroyl sarcosine and 36 parts of deionized water.
A kind of preparation method of children's mothproof toothpaste, comprising the following steps:
1) 36 parts of clam betel are taken, dissection is cleaned, slurry is then stirred for by blender, and pass through extrusion by its
Filtering is squeezed, removal fiber impurity obtains the first slurries, and finally sealed saves, spare；
2) 20 parts of sea-buckthorn, 9 parts of Chinese gall, 7 parts of galla turcica are taken, puts into and is crushed to 400 mesh in pulverizer, then carry out hot pressing
Processing, hot-pressing processing temperature are 120 DEG C, pressure 1.2MPa, time 16min and temperature are finally promoted to 150 DEG C, pressure
It will be 0.7MPa, time 9min, hot pressing mixed-powder is made, it is spare；
3) 15 parts of mushroom, 10 parts of Cortex Magnoliae Officinalis, 7 parts of rhizoma corydalis are taken, puts into and is crushed to 400 mesh in pulverizer, then put baking into
In case, 5min is toasted using 100 DEG C of temperature, then temperature is improved to 130 DEG C, continue baking time 26min, baking powder is made
End, it is spare；
4) the first slurries are made in step 1), hot pressing mixed-powder is made in step 2) and step 3) is made baking powder and puts into
It is stirred mixing in container, then carries out supercritical carbon dioxide extracting, control carbon dioxide flow is 100L/h, initial temperature
Degree is 60 DEG C, pressure 70MPa, time 36min, and temperature is then promoted to 85 DEG C, and pressure is reduced to 13MPa, time 5h,
Temperature is finally reduced to 40 DEG C, pressure is reduced to 7MPa, extracts and supercritical carbon dioxide extracting object is made, spare；
5) 28 parts of eggshell are taken, is put into baking box, 16min is toasted using 130 DEG C of temperature, then cools the temperature to 60
DEG C, continue baking time 9min, finally puts baked eggshell into ball mill ball grinds, the ball milling speed of ball mill is
Baking eggshell powder is made in 600rpm, spare；
6) 9 parts of xylitol, 9 parts of Nisin, 5 parts of hydroxypropyl guar gum, 7 parts of sodium lauroyl sarcosine and deionized water are taken
It 36 parts, puts into blender and is stirred, then mixing speed 800rpm, time 30min put into and carry out water-bath in container
Heating, and controlling bath temperature is 40 DEG C, heating time 18min, and heating water bath material is made, it is spare；
7) supercritical carbon dioxide extracting object is made in step 4), baking eggshell powder is made in step 5) and step 6) is made
Heating water bath material is put into emulsion pot, is then added 50 parts and 16 parts of betulin of sorbierite and is stirred mixing, stirring is completed
After emulsified, finally by the lotion being emulsified into carry out vacuum outgas to get.
Embodiment 2
A kind of children's mothproof toothpaste, is made of the material of following weight: 20 parts of clam betel, 32 parts of sea-buckthorn, white birch
30 parts of lipidol, 25 parts of mushroom, 20 parts of Cortex Magnoliae Officinalis, 17 parts of Chinese gall, 15 parts of rhizoma corydalis, 13 parts of galla turcica, 66 parts of sorbierite, eggshell 38
Part, 13 parts of xylitol, 17 parts of Nisin, 11 parts of hydroxypropyl guar gum, 11 parts of sodium lauroyl sarcosine and 50 parts of deionized water.
A kind of preparation method of children's mothproof toothpaste, comprising the following steps:
1) 20 parts of clam betel are taken, dissection is cleaned, slurry is then stirred for by blender, and pass through extrusion by its
Filtering is squeezed, removal fiber impurity obtains the first slurries, and finally sealed saves, spare；
2) 32 parts of sea-buckthorn, 17 parts of Chinese gall, 13 parts of galla turcica are taken, puts into and is crushed to 300 mesh in pulverizer, then carries out heat
Pressure processing, hot-pressing processing temperature are 100 DEG C, pressure 0.8MPa, time 10min, temperature are finally promoted to 130 DEG C, pressure
Power will be 0.5MPa, time 5min, and hot pressing mixed-powder is made, spare；
3) 25 parts of mushroom, 20 parts of Cortex Magnoliae Officinalis, 15 parts of rhizoma corydalis are taken, puts into and is crushed to 300 mesh in pulverizer, then put baking into
In case, 3min is toasted using 90 DEG C of temperature, then temperature is improved to 120 DEG C, continue baking time 20min, baking powder is made
End, it is spare；
4) the first slurries are made in step 1), hot pressing mixed-powder is made in step 2) and step 3) is made baking powder and puts into
It is stirred mixing in container, then carries out supercritical carbon dioxide extracting, control carbon dioxide flow is 80L/h, initial temperature
Degree is 50 DEG C, pressure 60MPa, time 30min, and temperature is then promoted to 75 DEG C, and pressure is reduced to 7MPa, time 3h,
Temperature is finally reduced to 30 DEG C, pressure is reduced to 3MPa, extracts and supercritical carbon dioxide extracting object is made, spare；
5) 38 parts of eggshell are taken, is put into baking box, 10min is toasted using 120 DEG C of temperature, then cools the temperature to 50
DEG C, continue baking time 7min, finally puts baked eggshell into ball mill ball grinds, the ball milling speed of ball mill is
Baking eggshell powder is made in 500rpm, spare；
6) take 13 parts of xylitol, 17 parts of Nisin, 11 parts of hydroxypropyl guar gum, 11 parts of sodium lauroyl sarcosine and go from
50 parts of sub- water, puts into blender and is stirred, mixing speed 600rpm, time 20min, then puts into container and carries out
Heating water bath, and controlling bath temperature is 30 DEG C, heating time 10min, and heating water bath material is made, it is spare；
7) supercritical carbon dioxide extracting object is made in step 4), baking eggshell powder is made in step 5) and step 6) is made
Heating water bath material is put into emulsion pot, is then added 66 parts and 30 parts of betulin of sorbierite and is stirred mixing, stirring is completed
After emulsified, finally by the lotion being emulsified into carry out vacuum outgas to get.
Embodiment 3
A kind of children's mothproof toothpaste, is made of the material of following weight: 28 parts of clam betel, 26 parts of sea-buckthorn, white birch
23 parts of lipidol, 20 parts of mushroom, 15 parts of Cortex Magnoliae Officinalis, 13 parts of Chinese gall, 11 parts of rhizoma corydalis, 10 parts of galla turcica, 58 parts of sorbierite, eggshell 33
Part, 11 parts of xylitol, 13 parts of Nisin, 8 parts of hydroxypropyl guar gum, 9 parts of sodium lauroyl sarcosine and 43 parts of deionized water.
A kind of preparation method of children's mothproof toothpaste, comprising the following steps:
1) 28 parts of clam betel are taken, dissection is cleaned, slurry is then stirred for by blender, and pass through extrusion by its
Filtering is squeezed, removal fiber impurity obtains the first slurries, and finally sealed saves, spare；
2) 26 parts of sea-buckthorn, 13 parts of Chinese gall, 10 parts of galla turcica are taken, puts into and is crushed to 350 mesh in pulverizer, then carries out heat
Pressure processing, hot-pressing processing temperature are 110 DEG C, pressure 1.0MPa, time 13min, temperature are finally promoted to 140 DEG C, pressure
Power will be 0.6MPa, time 7min, and hot pressing mixed-powder is made, spare；
3) 20 parts of mushroom, 15 parts of Cortex Magnoliae Officinalis, 11 parts of rhizoma corydalis are taken, puts into and is crushed to 350 mesh in pulverizer, then put baking into
In case, 4min is toasted using 95 DEG C of temperature, then temperature is improved to 125 DEG C, continue baking time 23min, baking powder is made
End, it is spare；
4) the first slurries are made in step 1), hot pressing mixed-powder is made in step 2) and step 3) is made baking powder and puts into
It is stirred mixing in container, then carries out supercritical carbon dioxide extracting, control carbon dioxide flow is 90L/h, initial temperature
Degree is 55 DEG C, pressure 65MPa, time 33min, and temperature is then promoted to 80 DEG C, and pressure is reduced to 10MPa, time 4h,
Temperature is finally reduced to 35 DEG C, pressure is reduced to 5MPa, extracts and supercritical carbon dioxide extracting object is made, spare；
5) 33 parts of eggshell are taken, is put into baking box, 13min is toasted using 125 DEG C of temperature, then cools the temperature to 55
DEG C, continue baking time 8min, finally puts baked eggshell into ball mill ball grinds, the ball milling speed of ball mill is
Baking eggshell powder is made in 550rpm, spare；
6) 11 parts of xylitol, 13 parts of Nisin, 8 parts of hydroxypropyl guar gum, 9 parts of sodium lauroyl sarcosine and deionization are taken
It 43 parts of water, puts into blender and is stirred, then mixing speed 700rpm, time 25min put into and carry out water in container
Bath heating, and controlling bath temperature is 35 DEG C, heating time 14min, and heating water bath material is made, it is spare；
7) supercritical carbon dioxide extracting object is made in step 4), baking eggshell powder is made in step 5) and step 6) is made
Heating water bath material is put into emulsion pot, is then added 58 parts and 23 parts of betulin of sorbierite and is stirred mixing, stirring is completed
After emulsified, finally by the lotion being emulsified into carry out vacuum outgas to get.
Experimental example:
Experimental subjects: choosing 40 children with decayed tooth and be divided into four groups, every group of 10 people.
It is control group, the other three groups teeth prepared using the embodiment of the present invention that one group, which is chosen, using the mothproof sound of baby talk cream of sodium fluoride
Cream is experimental group.
Requirement of experiment, four groups are brushed teeth 30 days using toothpaste respectively.
Table 1 is acquisition information acquired results after experimental subjects experiment
Table 1
Table 2 is that the toothpaste in experiment uses GB8372-2001 testing standard test result
Table 2
In conjunction with table 1 and table 2, the preventing child decayed tooth of the mothproof sound of baby talk cream of sodium fluoride and preparation of the embodiment of the present invention is compared
Cream, it can be seen that a kind of children's mothproof toothpaste of the present invention not only has good anti-decayed tooth performance, moreover it is possible to tooth-whitening and right
Oral cavity is non-stimulated and non-hazardous to body, and can satisfy toothpaste examination criteria.
Beneficial effects of the present invention: by add herb extract, make its with the process of brushing teeth be attached to decayed tooth facing into
Row treatment；Wherein contain Cortex Magnoliae Officinalis alcohol in Cortex Magnoliae Officinalis extract, Cortex Magnoliae Officinalis alcohol has special, lasting myorelaxant effects and extremely strong
Antibacterial action can be inhibited and be killed to main cariogenic bacteria Streptococcus mutans in oral cavity etc., and mushroom contains lentinan body, energy
Inhibit intraoral pathogen growth, prevent plaque from being formed, prevent saprodontia, Cortex Magnoliae Officinalis inhibition and killing oral cavity can be cooperateed with mainly cariogenic
Bacterium, in addition mushroom also contains ergosterol, and ergosterol can be transformed into vitamin D through solar radiation, enhance human immunological competence,
Tooth growth is helped, the generation of saprodontia phenomenon is further reduced；Betulin is natural inhibitor, is conducive to tooth and gum
Health effectively prevent decayed tooth, gingivitis and periodontitis；And what is selected is all extract in natural Chinese medicinal herb, for children
It is nontoxic, children's torso will not be impacted when treating Pediatric Oral Emergency problem.
Typical case arranges: Wu, 6 years old little girl, has decayed tooth in oral cavity, ineffective and small using a plurality of mothproof sound of baby talk cream
Child be unwilling using；A kind of children's mothproof toothpaste of the invention is used upon somebody's introduction, and after one month, decayed tooth is disappeared, tooth
Also bleach, child also oneself can actively brush teeth.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
The change or replacement expected without creative work, should be covered by the scope of protection of the present invention.
Claims (4)
1. a kind of children's mothproof toothpaste, it is characterised in that: be made of the material of following weight: 20-36 parts of clam betel, sand
20-32 parts of spine, 16-30 parts of betulin, 15-25 parts of mushroom, 10-20 parts of Cortex Magnoliae Officinalis, 9-17 parts of Chinese gall, 7-15 parts of rhizoma corydalis,
7-13 parts of galla turcica, 50-66 parts of sorbierite, 28-38 parts of eggshell, 9-13 parts of xylitol, 9-17 parts of Nisin, hydroxypropyl guar
5-11 parts of glue, 7-11 parts of sodium lauroyl sarcosine and 36-50 parts of deionized water.
2. a kind of children's mothproof toothpaste as described in claim 1, it is characterised in that: be made of the material of following weight:
36 parts of clam betel, 20 parts of sea-buckthorn, 16 parts of betulin, 15 parts of mushroom, 10 parts of Cortex Magnoliae Officinalis, 9 parts of Chinese gall, 7 parts of rhizoma corydalis, galla turcica
7 parts, 50 parts of sorbierite, 28 parts of eggshell, 9 parts of xylitol, 9 parts of Nisin, 5 parts of hydroxypropyl guar gum, sodium lauroyl sarcosine 7
Part and 36 parts of deionized water.
3. a kind of children's mothproof toothpaste as described in claim 1, it is characterised in that: be made of the material of following weight:
20 parts of clam betel, 30 parts of betulin, 25 parts of mushroom, 20 parts of Cortex Magnoliae Officinalis, 17 parts of Chinese gall, 15 parts of rhizoma corydalis, is not eaten at 32 parts of sea-buckthorn
Sub 13 parts, 66 parts of sorbierite, 38 parts of eggshell, 13 parts of xylitol, 17 parts of Nisin, 11 parts of hydroxypropyl guar gum, lauroyl flesh
11 parts and 50 parts of deionized water of propylhomoserin sodium.
4. a kind of children's mothproof toothpaste as described in claim 1, it is characterised in that: be made of the material of following weight:
28 parts of clam betel, 23 parts of betulin, 20 parts of mushroom, 15 parts of Cortex Magnoliae Officinalis, 13 parts of Chinese gall, 11 parts of rhizoma corydalis, is not eaten at 26 parts of sea-buckthorn
Sub 10 parts, 58 parts of sorbierite, 33 parts of eggshell, 11 parts of xylitol, 13 parts of Nisin, 8 parts of hydroxypropyl guar gum, lauroyl flesh ammonia
9 parts and 43 parts of deionized water of sour sodium.
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| CN201811261016.2A CN109260130A (en) | 2018-10-26 | 2018-10-26 | A kind of children's mothproof toothpaste and preparation method thereof |
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| CN201811261016.2A CN109260130A (en) | 2018-10-26 | 2018-10-26 | A kind of children's mothproof toothpaste and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2751810C1 (en) * | 2020-12-18 | 2021-07-19 | Федеральное государственное автономное образовательное учреждение высшего образования "Северо-Восточный федеральный университет имени М.К.Аммосова" | Method for treatment of chronic periodontitis |
| RU2784726C1 (en) * | 2022-10-20 | 2022-11-29 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кировский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Therapeutic and prophylactic toothpaste based on betulin |
| CN115554334A (en) * | 2022-09-23 | 2023-01-03 | 拜斯特药业(广州)有限公司 | Caries preventing coating agent capable of being applied to teeth and having relieving effect and preparation method thereof |
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