CN109010144A - A kind of baby's maintenance cream and preparation method thereof - Google Patents
A kind of baby's maintenance cream and preparation method thereof Download PDFInfo
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- CN109010144A CN109010144A CN201811210125.1A CN201811210125A CN109010144A CN 109010144 A CN109010144 A CN 109010144A CN 201811210125 A CN201811210125 A CN 201811210125A CN 109010144 A CN109010144 A CN 109010144A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The embodiment of the invention discloses a kind of baby's maintenance cream and preparation method thereof rich in vegetable Chinese herbal medicine extraction component.The raw material of the maintenance cream includes moisturizer, pH adjusting agent, absorbent, emollient, skin conditioning agent and water etc.；Especially containing vegetable Chinese herbal medicines extraction components such as Radix Pulsatillae extract, Herba speranskiae tuberculatae extract, scutellariae,radix powder.The preferably a variety of natural traditional Chinese medicines of this product refine, natural, mild, releive, is hormone-free；It is easy to use simultaneously, economic cost is lower.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of baby's maintenance cream and preparation method thereof.
Background technique
The report display of health ministry cosmetics adverse reaction monitoring, causes the common composition of infant skin allergy for perfume
Material, pigment and preservative.It is easy currently, the products that many is used for infant in the market are all added to preservative, essence, pigment etc.
The ingredient to threaten to infantile health.
According to studies have shown that the healthy skin surface of infant is weakly acidic, skin barrier function is weak, and skin thickness only has
The features such as adult one third has the ability for adjusting soda acid equilibrium poor, and structural development is incomplete, is easy to generate baby
The skin diseases such as quick, eczema.Therefore for the higher and higher using product requirement and standard of infant.In recent years, extraneous to solve
The injury of environment and washing product to infant, use is prevention first, followed by when infant has mild skin disease
It waits, the mild product containing vegetable Chinese herbal medicine ingredient is taken to carry out maintenance.
The skin repair product for being currently used for infant is difficult to avoid that the addition of the chemical components such as preservative, essence, pigment,
It cannot be truly realized safe, natural, clean.
Summary of the invention
The embodiment of the present invention is designed to provide a kind of baby's maintenance cream, which uses the camellia seed oil of natural epidemic disaster in booth sum
Cooperating the Chinese medicinal herb essences such as kuh-seng, radix scutellariae, the delicate skin of maintenance baby of releiving aims at the no added preservation formulations of baby's research and development,
Baby's skin is enabled to feel more water profit soft and smooth.It is a maintenance cream really used suitable for baby, avoids any chemical component
Addition, be truly realized safety, natural, clean.The embodiment of the invention also provides the preparation methods of baby's maintenance cream.
To achieve the above object, the embodiment of the present invention provides a kind of baby's maintenance cream, and baby's maintenance cream includes medium-height grass
Medicine extraction component mixture, the Chinese herbal medicine extraction component include Europe radix tarxaci powder, Radix Pulsatillae extract, lopseed extraction
Object, scutellariae,radix powder, kuh-seng powder and coptis root/handle powder.
Further, baby's maintenance cream include moisturizer, pH adjusting agent, absorbent, emollient, skin conditioning agent and
Water, wherein the skin conditioning agent includes that borneol, allantoin, bisabolol, menthol and the Chinese herbal medicine extraction component are mixed
Close object.
Further, the Chinese herbal medicine extraction component mixture includes that water, butanediol, Europe radix tarxaci powder, the Chinese bulbul mention
Object, Herba speranskiae tuberculatae extract, scutellariae,radix powder, kuh-seng powder and coptis root/handle powder are taken, by weight percentage, the Chinese herbal medicine extraction
Content of the constituents mixt in baby's maintenance cream is 20%~25%.
Europe dandelion (TARAXACUM OFFICINALE) root powder extracts in the root by Europe dandelion, according to there is anti-inflammatory anti-
The effect of bacterium and conditioning skin, when high concentration can vasodilator, can be used for face cream, toner and convergence product and hair
In care product.
The Chinese bulbul (PULSATILLA CHINENSIS) extract is the extract powder of ranunculaceae plant Chinese bulbul root, contains triterpene
Class saponin, have the function of it is clearing heat and detoxicating, remove heat from the blood and relieve diarrhea, removing dampness and destroying parasites, improving eyesight, disappear it is superfluous, have certain whitening efficacy.
Lopseed (PHRYMA LEPTOSTACHYA) extract is that euphorbia plant speranskia tuberculata or Balsaminaceae plant phoenix are celestial
Herb dry powder, with the deep effect of activating microcirculation and removing stasis medicinal, diuresis removing toxic substances, promoting menstruation.The swollen pain of boil, insect-bite can be controlled.With compared with
Good fungistatic effect.
Radix scutellariae (SCUTELLARIA BAICALENSIS) root powder is pale yellow powder made from the extracted drying of scutellariae,radix,
Have the function of anti-inflammatory, antimicrobial, antipyretic, calm.
Kuh-seng (SOPHORA FLAVESCENS) powder is powder made from the extracted drying of kuh-seng, the work with antibacterial anti-inflammatory
With, there is inhibiting effect to Propiobacterium, staphylococcus aureus, Escherichia coli, can be used for antiallergy, eases pain, treatment Huang
Subcutaneous ulcer, oedema are wet to itch.
The coptis (COPTIS CHINENSIS) root/handle powder is powder made from the extracted drying of coptis root/handle, contains barberry
Alkali (berberine), coptisine and jateorrhizine etc., to many types of shigella dysenteriae, typhoid fever, paratyphosum Bacterium, Escherichia coli, tubercle bacillus
Removing from office blue bacterium Deng majority has inhibiting effect.And has effects that clearing heat and detoxicating, hemostasis desinsection.
Further, the emollient includes cetostearyl alcohol, Parleam, dimethyl silicone polymer, deep-sea two
Save shepherd's purse (CRAMBE ABYSSINICA) seed oil, avocado (PERSEA GRATISSIMA) oil and camellia (CAMELLIA
JAPONICA) seed oil.
Further, the absorbent includes zinc oxide, and by weight percentage, the absorbent is in baby's maintenance
Content in cream is 4%-6%.
Further, the pH adjusting agent includes lactic acid, and by weight percentage, the pH adjusting agent is repaired in the baby
The content protected in cream is 0.2%-0.4%.
Further, the moisturizer includes glycerol, propylene glycol, butanediol and 1,2- pentanediol.
Further, baby's maintenance cream further includes antioxidant and emulsifier.For example, the antioxidant can be
Parahydroxyacet-ophenone, tocopherol acetate etc.；The emulsifier can be stearine, PEG-100 stearate etc..Or
Corresponding ingredient in prior art products also can be used in person, the antioxidant and emulsifier.
Further, baby's maintenance cream further includes antibacterial agent.For example, the antibacterial agent can be bright string ball
Bacterium/radish (RAPHANUS SATIVUS) root tunning filtrate.
The other side of the embodiment of the present invention additionally provides the preparation method of baby's maintenance cream, the method includes
The following steps:
(1) raw material are weighed according to certain proportion speed, while equipment keeps cleaning；
(2) allantoin mixed dissolution is added in water, part moisturizer at a certain temperature, is stirred evenly；
(3) emollient and emulsifier are uniformly mixed at a certain temperature, partial skin conditioner and pH adjusting agent are added,
It stirs evenly；
(4) step (2) and step (3) are mixed, homogeneous is simultaneously cooled to 45 DEG C；
(5) by remaining moisturizer, the remaining skin conditioning agent including the Chinese herbal medicine extraction component mixture, absorbent with
And other residual components are added in the mixture of step (4), stir evenly；
(6) mixture of step (5) is cooled to 38 DEG C, semi-finished product discharging；
(7) through filling, storage after the assay was approved.
Further, in step (2), the range of whipping temp is between 80-85 DEG C.
Further, in step (3), the range of whipping temp is between 68~73 DEG C.
Further, in step (4), the homogenizing time is in 8~12min.
Further, during from step (5) to step (6), step (5) stirs 30-40min.
The embodiment of the present invention has the advantages that
It is natural, mild, releive 1. preferred a variety of natural Chinese medicinal herbs refine, it is hormone-free.The camellia seed of natural epidemic disaster in booth sum
The Chinese medicinal herb essences such as oil cooperation kuh-seng, radix scutellariae, the delicate skin of maintenance baby of releiving, the no added anti-corrosion for aiming at baby's research and development are matched
Side enables baby's skin feel more water profit soft and smooth.
2. rigorously control product pH is faintly acid, close to infant's acid-base scale of skin.
3. the skin conditioning agent vegetable Chinese herbal medicine extraction component taken, pungent-warm has heat-clearing and damp-drying drug, control outside eczema, wet sore,
Removing toxic substances stagnation resolvation etc., the skin discomfort slight for maintenance infant has good effect.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily.
It should be clear that structure depicted in this specification, ratio, size etc., only to cooperate the revealed content of specification,
So that those skilled in the art understands and reads, enforceable qualifications are not intended to limit the invention, therefore do not have technology
On essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size can be generated not influencing the present invention
The effect of and the purpose that can reach under, should all still fall in the range of disclosed technology contents obtain and can cover.Together
When, cited such as "upper" in this specification, "lower", " left side ", right ", the term of " centre ", be merely convenient to describe bright
, rather than to limit the scope of the invention, relativeness is altered or modified, and is changing technology contents without essence
Under, when being also considered as the enforceable scope of the present invention.
Embodiment 1
The cream of baby's maintenance described in the present embodiment includes following component (based on baby's maintenance by weight percentage
Cream): moisturizer includes glycerol 5%, propylene glycol 4%, butanediol 4% and 1,2- pentanediol 1.5%；PH adjusting agent includes lactic acid
0.3%；Absorbent includes zinc oxide 5%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, poly dimethyl silicon
Oxygen alkane 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes borneol
0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture (butanediol, Ou Pu
Radix Herba Taraxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water) 22%；Antioxygen
Agent includes parahydroxyacet-ophenone 0.5% and tocopherol acetate 0.8%；(stearine, PEG-100 are stearic for emulsifier
Acid esters) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.2%；Remaining is water.
Preparation method includes the following steps:
(1) raw material are weighed according to certain proportion speed, while equipment keeps cleaning；
(2) allantoin mixed dissolution is added in water, part moisturizer at a certain temperature, is stirred evenly；Whipping temp 80
℃；
(3) emollient and emulsifier are uniformly mixed at a certain temperature, partial skin conditioner and pH adjusting agent are added,
It stirs evenly；70 DEG C of whipping temp；
(4) step (2) and step (3) are mixed, homogeneous is simultaneously cooled to 45 DEG C；Homogenizing time 10min；
(5) by remaining moisturizer, the remaining skin conditioning agent including the Chinese herbal medicine extraction component mixture, absorbent with
And other residual components are added in the mixture of step (4), stir evenly；Stir 30min；
(6) mixture of step (5) is cooled to 38 DEG C, semi-finished product discharging；
(7) through filling, storage after the assay was approved.
Following example 2-6, relative to embodiment 1, in addition to the partial parameters in method and step are adjusted, preparation side
Method is the same as embodiment 1.
Embodiment 2
Moisturizer includes glycerol 4%, propylene glycol 3%, butanediol 5% and 1,2- pentanediol 2%；PH regulator includes cream
Acid 0.2%；Absorbent includes zinc oxide 4%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, poly- diformazan
Radical siloxane 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes
Borneol 0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture (butanediol,
Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water) 22%；
Antioxidant includes parahydroxyacet-ophenone 0.4% and tocopherol acetate 0.9%；Emulsifier (stearine, PEG-100
Stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.2%；Remaining is water.
In preparation method, 83 DEG C of whipping temp of step (2)；72 DEG C of whipping temp of step (3)；Step (4) homogenizing time
In 8min；Step (5) stirs 35min.
Embodiment 3
Moisturizer includes glycerol 6%, propylene glycol 5%, butanediol 3% and 1,2- pentanediol 1%；PH regulator includes cream
Acid 0.4%；Absorbent includes zinc oxide 6%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, poly- diformazan
Radical siloxane 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes
Borneol 0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture (butanediol,
Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water) 22%；
Antioxidant includes parahydroxyacet-ophenone 0.6% and tocopherol acetate 0.7%；Emulsifier (stearine, PEG-100
Stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.2%；Remaining is water.
In preparation method, 85 DEG C of whipping temp of step (2)；71 DEG C of whipping temp of step (3)；Step (4) homogenizing time
In 9min；Step (5) stirs 40min.
Embodiment 4
Moisturizer includes glycerol 4.5%, propylene glycol 3.5%, butanediol 4.5% and 1,2- pentanediol 1.5%；PH is adjusted
Agent includes lactic acid 0.3%；Absorbent includes zinc oxide 5.5%；Emollient includes cetostearyl alcohol 11%, Parleam
9%, dimethyl silicone polymer 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin tune
Managing agent includes borneol 0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture
(butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract,
Water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.6% and tocopherol acetate 0.6%；Emulsifier (stearine,
PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.5%；Remaining is water.
In preparation method, 82 DEG C of whipping temp of step (2)；69 DEG C of whipping temp of step (3)；Step (4) homogenizing time
In 12min；Step (5) stirs 30min.
Embodiment 5
Moisturizer includes glycerol 5.5%, propylene glycol 4.5%, butanediol 3.5% and 1,2- pentanediol 2%；PH adjusting agent
Including lactic acid 0.3%；Absorbent includes zinc oxide 4.5%；Emollient include cetostearyl alcohol 11%, Parleam 9%,
Dimethyl silicone polymer 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin condition
Agent includes borneol 0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture
(butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract,
Water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.5% and tocopherol acetate 0.7%；Emulsifier (stearine,
PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.4%；Remaining is water.
In preparation method, 81 DEG C of whipping temp of step (2)；73 DEG C of whipping temp of step (3)；Step (4) homogenizing time
In 11min；Step (5) stirs 35min.
Embodiment 6
Moisturizer includes glycerol 5%, propylene glycol 4%, butanediol 4% and 1,2- pentanediol 1%；PH regulator includes cream
Acid 0.4%；Absorbent includes zinc oxide 4.5%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, poly- two
Methylsiloxane 4.5%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent packet
Include borneol 0.4%, allantoin 0.2%, bisabolol 0.2%, menthol 0.2% and Chinese herbal medicine extraction component mixture (fourth two
Alcohol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water)
22%；Antioxidant includes parahydroxyacet-ophenone 0.4% and tocopherol acetate 0.8%；Emulsifier (stearine,
PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.3%；Remaining is water.
In preparation method, 84 DEG C of whipping temp of step (2)；68 DEG C of whipping temp of step (3)；Step (4) homogenizing time
In 10min；Step (5) stirs 40min.
Following comparative example 1-4, relative to embodiment 1, in addition to not adding the ingredient lacked, preparation method is the same as embodiment 1.
Comparative example 1
Moisturizer includes glycerol 5%, butanediol 4% and 1,2- pentanediol 1.5%；PH adjusting agent includes lactic acid 0.5%；It inhales
Receiving agent includes zinc oxide 5%；Emollient includes Parleam 9%, dimethyl silicone polymer 4.5%, two section shepherd's purse seed of deep-sea
Oil 0.1%, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes allantoin 0.3%, bisabolol 0.2%, thin
Lotus alcohol 0.2% and Chinese herbal medicine extraction component mixture (butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, hardship
Join root powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.5% and tocopherol
Acetic acid esters 0.8%；Emulsifier (stearine, PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root fermentation
Product, water) 1.2%；Remaining is water.
Comparative example 2
Moisturizer includes glycerol 5%, propylene glycol 4% and 1,2- pentanediol 1.5%；PH adjusting agent includes lactic acid 0.5%；It inhales
Receiving agent includes zinc oxide 5%；Emollient includes cetostearyl alcohol 11%, dimethyl silicone polymer 4.5%, two section shepherd's purse seed oil of deep-sea
0.1%, camellia seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes borneol 0.4%, bisabolol 0.2%, menthol
0.2% and Chinese herbal medicine extraction component mixture (butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae
Powder, coptis root/handle powder, Herba speranskiae tuberculatae extract, water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.5% and tocopheryl acetate
Ester 0.8%；Emulsifier (stearine, PEG-100 stearate) 4%；(bright string coccus/radish root fermentation produces antibacterial agent
Object, water) 1.2%；Remaining is water.
Comparative example 3
Moisturizer includes glycerol 5%, propylene glycol 4% and butanediol 4%；PH adjusting agent includes lactic acid 0.1%；Absorbent packet
Include zinc oxide 5%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, two section shepherd's purse seed oil 0.1% of deep-sea, camellia
Seed oil 0.1% and avocado oil 0.1%；Skin conditioning agent includes borneol 0.4%, allantoin 0.2%, menthol 0.2% and medium-height grass
Medicine extraction component mixture (butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/
Handle powder, Herba speranskiae tuberculatae extract, water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.8% and tocopherol acetate 0.5%；Cream
Agent (stearine, PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.2%；
Remaining is water.
Comparative example 4
Moisturizer includes propylene glycol 4%, butanediol 4% and 1,2- pentanediol 1.5%；PH adjusting agent includes lactic acid 0.1%；
Absorbent includes zinc oxide 5%；Emollient includes cetostearyl alcohol 11%, Parleam 9%, dimethyl silicone polymer
4.5%；Skin conditioning agent includes borneol 0.4%, allantoin 0.2%, bisabolol 0.2% and Chinese herbal medicine extraction component mixture
(butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, scutellariae,radix powder, radix sophorae powder, coptis root/handle powder, Herba speranskiae tuberculatae extract,
Water) 22%；Antioxidant includes parahydroxyacet-ophenone 0.8% and tocopherol acetate 0.5%；Emulsifier (stearine,
PEG-100 stearate) 4%；Antibacterial agent (bright string coccus/radish root tunning, water) 1.2%；Remaining is water.
Detect test result
1,5g sample is respectively taken to the above embodiments 1-6 and comparative example 1-4 product obtained, according to Q/BT 1857-2013
Detection in terms of " moisturizing cream " standard requirements, progress organoleptic indicator and physical and chemical index, judgment basis are as follows:
Appearance (Q/BT 1857-2013): lotion is fine and smooth, the uniformity (product of addition insoluble granule or insoluble powder
Except)；
Fragrance (Q/BT 1857-2013): meet regulation odor type；
PH value (Q/BT 1857-2013): 4.0-8.5；
Heat-resisting (Q/BT 1857-2013): (40 ± 1) DEG C are kept for 24 hours, restore anhydrous oil separation phenomenon after room temperature；
Cold-resistant (Q/BT 1857-2013): (- 8 ± 2) DEG C are kept for 24 hours, preceding without explicitly with test after recovery room temperature
Shape difference.
As a result it see the table below.
1 organoleptic indicator of table and physical and chemical index testing result
It can be seen from Table 1 that the sample in embodiment 1-6 all meets every organoleptic indicator and physical and chemical index detection mark
Standard, wherein embodiment 1-3 has better desirable appearance and color relative to embodiment 4-6；Also, embodiment 1 has best
Appearance and color, be the yellow lotion of uniform and smooth, and as the suitable pH value of moisturizing cream.
In contrast, the sample in comparative example 1-4, appearance and character are not satisfactory；In addition, this four samples are heat-resisting
With occur different degrees of separation and/or caking phenomenon in cold-resistant detection.
Furthermore the sample in embodiment 1-6, relative to the sample in comparative example 1-4, pH value is distributed in relatively narrow range
It is interior, be conducive to product control；And the sample pH fluctuation in comparative example 1-4 is larger.
All test samples all meet fragrance examination criteria；But embodiment 4-6 is omited relative to the smell of other embodiments
Greatly, it may cause discomfort (such as to fragrance sensitive group) in some cases.
2, toxicology test is carried out to 1 sample of embodiment according to Ministry of Public Health's " cosmetics safety technical specification " (version in 2015)
(skin irritation test).
Tested material: yellow lotion, when experiment as former state.
2.1 experimental animals: 4 adults, healthy, skin zero damage regular grade new zealand rabbit are selected, by Guangdong Province's medicine
Experimental Animal Center (three water basely) provides [animal productiong licensing number: SCXK (Guangdong) 2014-0035, Quality of Experimental Animals conjunction
Lattice card number: 44411600004414], feed is supplied by collaboration medical bioengineering Co., Ltd of Jiangsu Province.
2.2 feeding managements: in regular grade animal house, (experimental animal uses credit number: SYXK (Guangdong) for new zealand rabbit raising
2016-0110), single cage is raised, free water feed, laboratory temperature: 16-26 DEG C, relative humidity: 40-70%RH.
2.3 contamination methods: regular grade new zealand rabbit 4, half male and half female.By experimental animal back backbone two sides quilt before test
Hair is cut, the left and right each about 3cm × 3cm of unhairing range.Tested material about 0.5g is taken to be applied on the left of animal on skin, application area
About 2.5cm × 2.5cm is smeared once daily, and continuous to smear 14 days, blank control is made in the other side.Since second day, apply every time
Preceding cropping is smeared, removes residual tested material with pure water, same processing is made in check plot.Result is observed after one hour.
2.4 observation operations: dermoreaction is observed under available light, is pressed " cosmetics safety technical specification " (version in 2015)
The standards of grading that skin irritation/corrosion test table 1 " skin wound repair scoring " provides carry out erythema and oedema
Scoring, is observed continuously 14 days.
2.5 evaluation of result: being calculated according to the following formula daily every animal average integral after the test, by " cosmetics peace
Full technical specification " (version in 2015) skin irritation/corrosion test table 2 " skin irritatin strength grading " determine skin irritatin it is strong
Degree.
2.6 test results: there is skin wound repair in tested new zealand rabbit skin within the observation period, and sample sets are every daily
Animal integral mean value is 0.48 point.According to " cosmetics safety technical specification " (version in 2015) skin irritation/corrosion test
Standard judges that the multiple skin irritatin intensity of baby's maintenance cream of sample is nonirritant in 1-6 of the embodiment of the present invention.It the results are shown in Table
2。
2 tested material of table is to the multiple skin irritation test result of new zealand rabbit
Conclusion: tested material is nonirritant to the multiple skin irritation of new zealand rabbit.
3,7 sex hormone are carried out to 1 sample of embodiment according to Ministry of Public Health's " cosmetics safety technical specification " (version in 2015)
Detection, testing result are shown in Table 3.
Table 3 tested material, 7 sex hormone testing results
Conclusion: 7 sex hormone testing results of tested material are qualification.
4,40 a kind of measurement liquid chromatogram/series connection of glucocorticoid in product " is transferred according to GB/T 24800.2-2009
Mass spectrography and thin layer chromatography ", Ministry of Public Health's " cosmetics safety technical specification " (version in 2015) to 1 sample of embodiment carry out 41
Kind glucocorticoid measurement.Measurement result is shown in Table 4.
Table 4 tested material, 41 kinds of glucocorticoid measurement results
Conclusion: 41 kinds of glucocorticoid measurement results of tested material are qualification.
Baby's maintenance cream obtained of the embodiment of the present invention, using Chinese medicinal herb essence formula, and to various composition carry out section
Rationally compounding, the delicate skin of maintenance baby of releiving are learned, enables baby's skin feel more water profit soft and smooth.It is a really suitable for baby
The maintenance cream used, avoids the addition of any chemical component, has been truly realized safe, natural, clean.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (10)
1. a kind of baby's maintenance cream, which is characterized in that baby's maintenance cream includes Chinese herbal medicine extraction component mixture, it is described in
Herbal medicine extraction component includes Europe radix tarxaci powder, Radix Pulsatillae extract, Herba speranskiae tuberculatae extract, scutellariae,radix powder, kuh-seng powder and the coptis
Root/handle powder.
2. baby's maintenance cream according to claim 1, which is characterized in that baby's maintenance cream includes moisturizer, pH tune
Save agent, absorbent, emollient, skin conditioning agent and water, wherein the skin conditioning agent include borneol, allantoin, bisabolol,
Menthol and the Chinese herbal medicine extraction component mixture.
3. baby's maintenance cream according to claim 2, which is characterized in that the Chinese herbal medicine extraction component mixture includes
Water, butanediol, Europe radix tarxaci powder, Radix Pulsatillae extract, Herba speranskiae tuberculatae extract, scutellariae,radix powder, kuh-seng powder and coptis root/handle
Powder, by weight percentage, content of the Chinese herbal medicine extraction component mixture in baby's maintenance cream be 20%~
25%.
4. baby's maintenance cream according to claim 3, which is characterized in that the emollient includes cetostearyl alcohol, hydrogenation
Polyisobutene, dimethyl silicone polymer, two section shepherd's purse seed oil of deep-sea, avocado oil and camellia seed oil.
5. baby's maintenance cream according to claim 4, which is characterized in that the absorbent includes zinc oxide, with weight hundred
Divide than meter, content of the absorbent in baby's maintenance cream is 4%-6%.
6. baby's maintenance cream according to claim 5, which is characterized in that the pH adjusting agent includes lactic acid, with weight hundred
Divide than meter, content of the pH adjusting agent in baby's maintenance cream is 0.2%-0.4%.
7. baby's maintenance cream according to claim 6, which is characterized in that the moisturizer includes glycerol, propylene glycol, fourth two
Pure and mild 1,2- pentanediol.
8. baby's maintenance cream according to claim 7, which is characterized in that baby's maintenance cream further include antioxidant,
Emulsifier and antibacterial agent.
9. the preparation method of baby's maintenance cream according to claim 8, which is characterized in that the method includes following steps
It is rapid:
(1) raw material are weighed according to certain proportion speed, while equipment keeps cleaning；
(2) allantoin mixed dissolution is added in water, part moisturizer at a certain temperature, is stirred evenly；
(3) emollient and emulsifier are uniformly mixed at a certain temperature, partial skin conditioner and pH adjusting agent, stirring is added
Uniformly；
(4) step (2) and step (3) are mixed, homogeneous is simultaneously cooled to 45 DEG C；
(5) by remaining moisturizer, the remaining skin conditioning agent including the Chinese herbal medicine extraction component mixture, absorbent and its
Its residual components is added in the mixture of step (4), stirs evenly；
(6) mixture of step (5) is cooled to 38 DEG C, semi-finished product discharging；
(7) through filling, storage after the assay was approved.
10. preparation method according to claim 9, which is characterized in that
In step (2), the range of whipping temp is between 80-85 DEG C；
In step (3), the range of whipping temp is between 68~73 DEG C；
In step (4), the homogenizing time is in 8~12min；And
During from step (5) to step (6), step (5) stirs 30-40min.
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Cited By (1)
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| CN110787097A (en) * | 2019-12-19 | 2020-02-14 | 天津达仁堂京万红药业有限公司 | Plant extract body soothing milk and preparation method thereof |
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