CN110251611A - A kind of Chinese medicine composition and its preparation method and application with skin repair effect - Google Patents
A kind of Chinese medicine composition and its preparation method and application with skin repair effect Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61Q19/00—Preparations for care of the skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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Abstract
The present invention provides a kind of Chinese medicine compositions with skin repair effect, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 60~70 parts of rhizoma polygonati, 45~60 parts of Radix Ophiopogonis, 40~55 parts of aloe, 40~50 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, 25~30 parts of Chinese prickly ash, 1~5 part of kuh-seng, 1~5 part of ginseng.The present invention also provides the preparation method of the Chinese medicine composition and purposes.The traditional chinese medicine composition of the invention multi-flavor medicine compatible use, can tonifying speen and tonifying kidney, boosting qi and nourishing yin promotes the production of body fluid, activating blood and clearing heat is detoxified, heat-clearing and damp-drying drug.The traditional chinese medicine composition of the invention effect is good, it is quick, natural safety does not stimulate, clinical tests prove that, it can effectively improve skin gloss and compact degree, have the effects that moisturizing cleaning whitening, inhibit bacterium to generate, anti-oxidant, antipruritic, antiperspirant deodorization, softening skin, skin undesirable condition can be improved, restore the apparent state of skin natural gloss.It can be used for tanning severely, have dry skin, the prevention and treatment of acne, scytitis etc..
Description
Technical background
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition and its system with skin repair effect
Preparation Method and application.
Background technique
Skin problem is a kind of problem that most people can all encounter in daily life, problem skin and aging bring
Skin injury directly influences the healthy living and human body natural's state of people.Common skin problem has: skin surface is shown
Evidence for senescence, certain skin diseases and some other problems, such as dry, be greasy.
Since Pre-Qin Times, China begins to utilize natural Chinese medicinal herb beautifying skin；In abundant Zhou king period, people are by swallow
The red blue flower leaf of growth smashes juice congealed fat and kermes beauty and make-up is made；The Huangdi's Internal Classics of Qin Han the period of Three Kingdoms and " Huatuo highly skilled doctor is close
Pass " all describe many drugs with beauty functions；After the Tang Dynasty, the kind of cosmetics is increasingly rich, and SUN Si miao is in " a thousand pieces of gold
Wing side " in say that " face rouge hand cream, clothing perfume (or spice) bath beans, the expensive victory of bodyguard people are all wanted." know that the application of beautifying drug is very universal；
The factory that row has built up China's the first household production of machinery cosmetics is extensively given birth in Hong Kong in 1905, starts to produce floral water, toilet cream
With the cosmetics such as face powder.Spreading unchecked with synthetic after World War II, environment is heavily contaminated, and human health is injured,
Chemical synthesis cosmetics equally face this problem, and synthesis material contained therein, compound essence, synthetic dyestuff etc. often induce
All kinds of skin diseases have then worldwide started the development upsurge of natural cosmetics.
Chinese herbal medicine is much smaller to the side effect of human body for synthetic, so its safety is higher.
Active skull cap components contained therein, are widely used in modern cosmetics, and play various effects, and such as whitening spot-removing is prevented
Decline crease-resistant, anti-acne, sun-proof, moisturizing, anti-dandruff and itching-relieving etc..Nowadays China cosmetic is wide in variety, Chinese medicine cosmetic skin care product tool
There are higher popularity and brand effect, and researcher also to the active constituent in Chinese herbal medicine and its extracts separation, pharmacology machine
System has all carried out a large amount of research.
Simultaneously as continuous attention of the people to health, the washing product that can be used for skin repair are also concerned.Market
On skin washing product skin repair product by the source point of effective component, the addition of pure Chinese medicine herb extract can be divided into and changed
Learn synthesis material addition.But the washing product effect of addition Chinese medical extract is not satisfactory merely on the market at present, and some are repaired
Product are reproduced in order to pursue effect, to attract customer, increase sale, being added to some functional components in the product, (such as: tartaric acid swashs
Element, lead mercury, antibiotic etc.), skin has been injured instead, and many skins is caused to generate sequelae.Therefore, it is necessary to develop a low
Stimulation, pure green fanout free region, and the skin repair product that effect is good, for broad masses' use.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition and its preparation method and application with skin repair effect.
The present invention provides a kind of Chinese medicine compositions with skin repair effect, it is by the bulk pharmaceutical chemicals of following parts by weight
Be prepared: 60~70 parts of rhizoma polygonati, 45~60 parts of Radix Ophiopogonis, 40~55 parts of aloe, 40~50 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle,
25~30 parts of Chinese prickly ash, 1~5 part of kuh-seng, 1~5 part of ginseng.
Further, Chinese medicine composition above-mentioned is prepared by the bulk pharmaceutical chemicals of following parts by weight: 60~65 parts of rhizoma polygonati,
45~55 parts of Radix Ophiopogonis, 40~50 parts of aloe, 40~45 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, 25~30 parts of Chinese prickly ash, kuh-seng 1~5
Part, 1~5 part of ginseng.
Further, Chinese medicine composition above-mentioned is prepared by the bulk pharmaceutical chemicals of following parts by weight: 65~70 parts of rhizoma polygonati,
55~60 parts of Radix Ophiopogonis, 50~55 parts of aloe, 45~50 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, 25~30 parts of Chinese prickly ash, kuh-seng 1~5
Part, 1~5 part of ginseng.
Further, Chinese medicine composition above-mentioned is prepared by the bulk pharmaceutical chemicals of following parts by weight: 62 parts of rhizoma polygonati, Radix Ophiopogonis
47 parts, 43 parts of aloe, 42 parts of Rhizoma Chuanxiong, 30 parts of honeysuckle, 26 parts of Chinese prickly ash, 2 parts of kuh-seng, 2 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 63 parts of rhizoma polygonati, 48 parts of Radix Ophiopogonis, 43 parts of aloe, Rhizoma Chuanxiong 42
Part, 31 parts of honeysuckle, 26 parts of Chinese prickly ash, 3 parts of kuh-seng, 2 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 68 parts of rhizoma polygonati, 55 parts of Radix Ophiopogonis, 50 parts of aloe, Rhizoma Chuanxiong 48
Part, 34 parts of honeysuckle, 26 parts of Chinese prickly ash, 2 parts of kuh-seng, 4 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 70 parts of rhizoma polygonati, 58 parts of Radix Ophiopogonis, 53 parts of aloe, Rhizoma Chuanxiong 48
Part, 32 parts of honeysuckle, 27 parts of Chinese prickly ash, 3 parts of kuh-seng, 2 parts of ginseng.
The present invention also provides a kind of method for preparing Chinese medicine composition above-mentioned, it the following steps are included:
(1) raw material of each weight proportion is weighed；
(2) raw material mixed powder is broken, water heating extracting is distilled, is concentrated under reduced pressure, obtains extracting solution；
(3) by extracting solution it is cooling after, water extract-alcohol precipitation is concentrated under reduced pressure, it is dry to get.
Further,
In the step (2), heating extraction is to add water to cook 2 times, and one decocts the distilled water for adding 10~12 times of amounts (v/w), leaching
40min is steeped, is boiled, and keep slightly boiled 60min, is filtered；Two decoct the distilled water for adding 10~12 times of amounts (v/w), boil, and keep slightly boiled
Decoct 40min, filtering, merging filtrate；
And/or in step (2), it is concentrated under reduced pressure as combined filtrate decompression is concentrated into relative density at 60~70 DEG C
1.03~1.06 medical fluid；
And/or in step (3), being concentrated under reduced pressure to concentrate filtrate to relative density at 60~70 DEG C is 1.20
~1.30 clear cream；
And/or in step (3), dry is vacuum freeze drying or spray drying.
The present invention also provides Chinese medicine compositions above-mentioned to have cleaning moisture-keeping function, skin care, to skin in preparation
It is non-stimulated, with skin repair effect, easy cleaning washing product in purposes；
Preferably, it is described have skin repair as improve skin gloss and compact degree, whitening, inhibit bacterium generation,
Anti-oxidant, antipruritic, antiperspirant deodorization, softening skin, prevention and treatment sunburn, prevention and treatment dry skin, prevention and treatment acne, prevention and treatment scytitis.
Further, the washing product is shower cream, body lotion, body frost, protection cream.
The present invention also provides a kind of washing product, the washing product be with Chinese medicine composition above-mentioned be effectively at
Point, in addition daily chemicals field acceptable auxiliary material is prepared.
Further, the washing product is shower cream, body lotion, body frost, protection cream.
In the present invention, v/w is volume mass ratio, unit mL/g.
The traditional chinese medicine composition of the invention is by rhizoma polygonati, Radix Ophiopogonis, aloe, Rhizoma Chuanxiong, honeysuckle, Chinese prickly ash, kuh-seng, ginseng eight traditional chinese medicines
Composition.
Using rhizoma polygonati, Radix Ophiopogonis, aloe, Rhizoma Chuanxiong as monarch drug in a prescription, the sweet flat matter profit of rhizoma polygonati, effect mitigates Chinese medicine composition, enter spleen,
Lung, kidney channel, for the product of flat tonifying Qi yin；Radix Ophiopogonis hardship in sweet flavor rushes down, slightly cold heat-clearing, enters lung, the heart, stomach meridian, to nourish clear and rich product；Aloe
Bitter cold rushes down clearly, settles downlink, enters large intestine and Liver Channel, can purgating heat and bowels and, moreover it is possible to desinsection.Rhizoma Chuanxiong pungent-warm row dissipates,
Kind blood-activating and qi-promoting, wind-expelling pain-stopping.Sweet light, the thin fragrance thoroughly of trembling with fear of honeysuckle, can clearing heat and detoxicating dispelling wind and heat from the body；The hot perfume of Chinese prickly ash is dry,
Enter spleen, stomach, kidney channel, it is slightly poisonous and power is stronger.Energy desinsection, until abdominal pain due to enterositosis and pruitus.Kuh-seng bitter cold is dry clearly, under sedimentation
Row.Both it is apt to heat-clearing and damp-drying drug, wind dispelling insecticide and antipruritic, diuresis；Ginseng sweet and slight bitter, tepor and it is not very scorching, the efficacy of a drug is powerful, to mend
The key medicine of gas salubrity.
The traditional chinese medicine composition of the invention multi-flavor medicine compatible use, can tonifying speen and tonifying kidney, boosting qi and nourishing yin promote the production of body fluid, activating blood and clearing heat solution
Poison, heat-clearing and damp-drying drug.The traditional chinese medicine composition of the invention effect is good, quick, and natural safety does not stimulate, clinical tests prove that, it can be with
Effectively improve skin gloss and compact degree, have moisturizing cleaning whitening, inhibit bacterium generation, anti-oxidant, antipruritic, antiperspirant deodorization,
The effects of softening skin, can improve skin undesirable condition, restore the apparent state of skin natural gloss.It can be used for tanning severely, skin
The prevention and treatment of drying, acne, scytitis etc..
Obviously, above content according to the present invention is not being departed from according to the ordinary technical knowledge and customary means of this field
Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The specific embodiment of form by the following examples remakes further specifically above content of the invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on above content of the present invention
The technology realized all belongs to the scope of the present invention.
Specific embodiment
If the raw material used in the embodiment of the present invention is the common raw material of this field, embodiment without Special Statement
Employed in method, be the conventional method of this field.
1 present invention of embodiment has the preparation of the Chinese medicine composition of skin repair effect
1, raw material: 62 parts of rhizoma polygonati, 47 parts of Radix Ophiopogonis, 43 parts of aloe, 42 parts of Rhizoma Chuanxiong, 30 parts of honeysuckle, 26 parts of Chinese prickly ash, kuh-seng 2
Part, 2 parts of ginseng.
2, preparation method:
(1) each raw material is weighed in proportion；
(2) it by after above-mentioned each component co-grinding, with distillation water heating extracting, decocts altogether 2 times, pan-fried plus 11 times of amount (v/
W) water is impregnated 40 minutes, is boiled, and is kept for slightly boiled 60 minutes, filtering；Two decoct the water for adding 10 times of amounts (v/w), boil, and keep micro-
Boiling decocts 40 minutes, filtering, merging filtrate；At 60~70 DEG C by combined filtrate decompression be concentrated into relative density 1.03~
1.06 medical fluid obtains the extracting solution of medicinal material；
(3) by after extracting solution cooling, water extract-alcohol precipitation, it is 1.20 that relative density is concentrated filtrate at 60~70 DEG C
~1.30 clear cream；By clear cream vacuum freeze drying to get the Chinese medicine composition with skin repair function.
2 present invention of embodiment has the preparation of the Chinese medicine composition of skin repair effect
1, raw material: 63 parts of rhizoma polygonati, 48 parts of Radix Ophiopogonis, 43 parts of aloe, 42 parts of Rhizoma Chuanxiong, 31 parts of honeysuckle, 26 parts of Chinese prickly ash, kuh-seng 3
Part, 2 parts of ginseng.
2, preparation method:
(1) each raw material is weighed in proportion；
(2) it by after above-mentioned each component co-grinding, with distillation water heating extracting, decocts altogether 2 times, pan-fried plus 11 times of amount (v/
W) water is impregnated 40 minutes, is boiled, and is kept for slightly boiled 60 minutes, filtering；Two decoct the water for adding 10 times of amounts (v/w), boil, and keep micro-
Boiling decocts 40 minutes, filtering, merging filtrate；At 60~70 DEG C by combined filtrate decompression be concentrated into relative density 1.03~
1.06 medical fluid obtains the extracting solution of medicinal material；
(3) by after extracting solution cooling, water extract-alcohol precipitation, it is 1.20 that relative density is concentrated filtrate at 60~70 DEG C
~1.30 clear cream；Clear cream is spray-dried to get the Chinese medicine composition with skin repair function.
3 present invention of embodiment has the preparation of the Chinese medicine composition of skin repair effect
1, raw material: 68 parts of rhizoma polygonati, 55 parts of Radix Ophiopogonis, 50 parts of aloe, 48 parts of Rhizoma Chuanxiong, 34 parts of honeysuckle, 26 parts of Chinese prickly ash, kuh-seng 2
Part, 4 parts of ginseng.
2, preparation method:
(1) each raw material is weighed in proportion；
(2) it by after above-mentioned each component co-grinding, with distillation water heating extracting, decocts altogether 2 times, pan-fried plus 11 times of amount (v/
W) water is impregnated 40 minutes, is boiled, and is kept for slightly boiled 60 minutes, filtering；Two decoct the water for adding 10 times of amounts (v/w), boil, and keep micro-
Boiling decocts 40 minutes, filtering, merging filtrate；At 60~70 DEG C by combined filtrate decompression be concentrated into relative density 1.03~
1.06 medical fluid obtains the extracting solution of medicinal material；
(3) by after extracting solution cooling, water extract-alcohol precipitation, it is 1.20 that relative density is concentrated filtrate at 60~70 DEG C
~1.30 clear cream；Clear cream is spray-dried to get the Chinese medicine composition with skin repair function.
4 present invention of embodiment has the preparation of the Chinese medicine composition of skin repair effect
1, raw material: 70 parts of rhizoma polygonati, 58 parts of Radix Ophiopogonis, 53 parts of aloe, 48 parts of Rhizoma Chuanxiong, 32 parts of honeysuckle, 27 parts of Chinese prickly ash, kuh-seng 3
Part, 2 parts of ginseng.
2, preparation method:
(1) each raw material is weighed in proportion；
(2) it by after above-mentioned each component co-grinding, with distillation water heating extracting, decocts altogether 2 times, pan-fried plus 11 times of amount (v/
W) water is impregnated 40 minutes, is boiled, and is kept for slightly boiled 60 minutes, filtering；Two decoct the water for adding 10 times of amounts (v/w), boil, and keep micro-
Boiling decocts 40 minutes, filtering, merging filtrate；At 60~70 DEG C by combined filtrate decompression be concentrated into relative density 1.03~
1.06 medical fluid obtains the extracting solution of medicinal material；
(3) by after extracting solution cooling, water extract-alcohol precipitation, it is 1.20 that relative density is concentrated filtrate at 60~70 DEG C
~1.30 clear cream；By clear cream vacuum freeze drying to get the Chinese medicine composition with skin repair function.
The shower cream with skin repair function of 5 the traditional chinese medicine composition of the invention of embodiment preparation
1, shower cream of the present invention is grouped as by the group of following mass percentage: deionized water 74.79%, laureth
Sulfuric ester ammonium 10%, Cocoamidopropyl betaine 3%, coconut oleoyl amine MEA1%, laruyl alcohol sodium sulfovinate 4%, Chinese traditional medicine composition
Object 2%, panthenol 0.1%, urea 0.1%, glycerol 0.1%, lactic acid 0.1%, Anjidew NL50 0.1%, sodium chloride 0.4%, 1,2- oneself two
Alcohol 0.1%, pungent glycol 0.1%, allantoin 0.1%, Sodium Hyaluronate 0.1%, polyquaternium -7 1.5%, acrylic acid (ester) class
Copolymer 2%, EDETATE SODIUM 0.1%, methylisothiazolinone 0.01%, essence 0.3%.
2, shower cream of the present invention the preparation method is as follows:
(1) all production apparatus are cleaned and is disinfected；
(2) deionized water, laureth sulfuric ester ammonium, cocamidopropyl propyl amide is added according to formula rate in vacuum kettle
Glycine betaine, coconut oleoyl amine MEA, laruyl alcohol sodium sulfovinate, EDETATE SODIUM, are stirred evenly, and heat up with the revolving speed of 10~15r/min
To 80~85 DEG C, after stirring to no particle-liquid, 20 minutes are kept the temperature, cooling；
(3) after cooling to 60 degree, the cooling water-reducible acrylic acid of ion (ester) analog copolymer of addition (dilution ratio 1:
1), continue to stir at low speed cooling after mixing evenly.
(4) after cooling to 45 degree, remaining whole raw materials are added, stirring 20min is uniform to Material.It takes a shower up to the present invention
Dew.
Beneficial effects of the present invention are illustrated below by way of test example.
The evaluation of 1 the traditional chinese medicine composition of the invention of test example
According to " cosmetics safety technical specification " (version in 2015), the Chinese medicine of " company standard " evaluation Examples 1 to 4 preparation
Composition, physico index and microbiological indicator result are as shown in Table 1 and Table 2.
The physico metrics evaluation result of 1 the traditional chinese medicine composition of the invention of table
The microbiological indicator evaluation result of 2 the traditional chinese medicine composition of the invention of table
| Strain | Standard regulation | Microbiological indicator evaluation result of the present invention |
| Total plate count (CFU/g or CFU/mL) | ≤500 | Meet regulation |
| Yeast and mold sum (CFU/g or CFU/mL) | ≤1000 | Meet regulation |
| Heat-resisting coliform/g (or mL) | It must not detect | It is not detected |
| Staphylococcus aureus/g (or mL) | It must not detect | It is not detected |
| Pseudomonas aeruginosa/g (or mL) | It must not detect | It is not detected |
Testing result is shown, in the traditional chinese medicine composition of the invention, reduces lead, total arsenic, the content of the heavy metals such as total mercury, by lead
Content control within 10mg/kg, the content of total arsenic controls within 2mg/kg, the content control of total mercury 1mg/kg with
It is interior, it has no toxic and side effect to human body, and microorganism indices reach criterion of acceptability.
The performance measurement of the shower cream of the present invention of test example 2
According to GB/T 34857-2017 bath agent national standard to the shower cream prepared by Examples 1 to 4 Chinese medicine composition
Physico-chemical tests are carried out, gained Testing index result is as follows.
(1) character detects
Shower cream of the invention is white pearlescent shape mucus, has peat-reek, fine and smooth uniform.
(2) pH value detects
Shower cream of the invention is sampled, is measured with pH meter, measuring pH value is 4~5.
(3) viscosity number detects
Shower cream of the invention is sampled, is measured with viscosimeter, measuring viscosity number is 2000.
(4) Detection of Stability
Sample shower cream of the invention, be encapsulated in transparence cosmetic bottle, be respectively placed in quartz lamp illumination, -15 DEG C,
5 DEG C, 2 DEG C, under 48 DEG C of experiment conditions, appearance, fragrance, pH value, viscosity and other days are carried out with lasting survey in 3 months by a definite date
Examination, sees whether the bad phenomenons such as bleed, layering, separation, precipitating, discoloration, peculiar smell, demulsification occur, testing result shows above
Bad result does not appear in test process, and illustrating shower cream of the invention, it has good stability.
(5) centrifugation detection
Shower cream of the invention is sampled, is encapsulated in centrifuge tube and is centrifuged 30min under 3000r/min revolving speed, is observed
Whether not dispersion component is occurred, and testing result shows not dispersion component do not occur, illustrates its Combination of shower cream of the invention
It is good.
(6) stimulation anaphylaxis detects
Shower cream of the invention is sampled, it is applied on volunteer (18~58 years old, 300 people) the back of the hand in right amount and observes 30min,
See whether it phenomena such as redness, dermexanthesis, blistering occurs, observation indicate that, ill symptoms do not occur, and illustrate of the invention wash one's hair
Bath lotion will not generate stimulation and allergic phenomena to skin.
(7) shower cream resultant effect detects
Using opinion poll point system, commented by asking volunteer to try out shower cream of the invention and filling in table on probation to integrate
Valence.Respectively choose different age group volunteer (18~38 years old, 100 people；38~58 years old, 100 people) as object on probation, daily
It has a bath 1 time, is used continuously three months, fill in table on probation after on probation and score.Every using effect total score is 5 in grade form
Point: 5 points are best results, are indicated very satisfied；4 points are preferably, to be relatively satisfied with；3 points are that can receive；3 points the following are not
Acceptable range.Every using effect average situation is shown in Table 3.(note: with 1~3 Chinese medicine composition of the embodiment of the present invention
The shower cream of preparation is test sample).
The shower cream resultant effect testing result of the present invention of table 3
| Using effect | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Clean level | 4.98 | 5.00 | 4.98 |
| Moisturizing degree | 4.95 | 4.9 | 4.85 |
| Foam degree | 4.96 | 4.93 | 4.96 |
| The degree of moistening | 4.94 | 4.86 | 4.96 |
| Rinse complexity | 4.94 | 4.95 | 4.80 |
| Non-stimulated degree | 5.00 | 4.92 | 4.94 |
| Skin repair | 5.00 | 4.90 | 5.00 |
| Total score | 34.77 | 34.46 | 34.49 |
As shown in table 3, the shower cream of 1~3 Chinese medicine composition of embodiment of the present invention preparation is in skin care, moisturizing, flushing
Good effect is obtained in terms of difficulty, cleaning effect, non-stimulated degree, especially skin repair.
To sum up, the traditional chinese medicine composition of the invention multi-flavor medicine compatible use, can tonifying speen and tonifying kidney, boosting qi and nourishing yin promote the production of body fluid, invigorate blood circulation, clearly
Thermal detoxification, heat-clearing and damp-drying drug.The traditional chinese medicine composition of the invention effect is good, quick, and natural safety does not stimulate, clinical tests prove that,
It can effectively improve skin gloss and compact degree, there is moisturizing cleaning whitening, bacterium generation, anti-oxidant, antipruritic, antiperspirant is inhibited to prevent
The effects of smelly, softening skin, can improve skin undesirable condition, restore the apparent state of skin natural gloss.It can be used for tanning severely, skin
The prevention and treatment of skin drying, acne, scytitis etc..
Claims (10)
1. a kind of Chinese medicine composition with skin repair effect, it is characterised in that: it is by the bulk pharmaceutical chemicals system of following parts by weight
It is standby to form: 60~70 parts of rhizoma polygonati, 45~60 parts of Radix Ophiopogonis, 40~55 parts of aloe, 40~50 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, flower
25~30 parts of green pepper, 1~5 part of kuh-seng, 1~5 part of ginseng.
2. Chinese medicine composition according to claim 1, it is characterised in that: it be by following parts by weight bulk pharmaceutical chemicals preparation and
At: 60~65 parts of rhizoma polygonati, 45~55 parts of Radix Ophiopogonis, 40~50 parts of aloe, 40~45 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, Chinese prickly ash 25
~30 parts, 1~5 part of kuh-seng, 1~5 part of ginseng.
3. Chinese medicine composition according to claim 1, it is characterised in that: it be by following parts by weight bulk pharmaceutical chemicals preparation and
At: 65~70 parts of rhizoma polygonati, 55~60 parts of Radix Ophiopogonis, 50~55 parts of aloe, 45~50 parts of Rhizoma Chuanxiong, 30~35 parts of honeysuckle, Chinese prickly ash 25
~30 parts, 1~5 part of kuh-seng, 1~5 part of ginseng.
4. described in any item Chinese medicine compositions according to claim 1~3, it is characterised in that: it is by the original of following parts by weight
Material medicine be prepared: 62 parts of rhizoma polygonati, 47 parts of Radix Ophiopogonis, 43 parts of aloe, 42 parts of Rhizoma Chuanxiong, 30 parts of honeysuckle, 26 parts of Chinese prickly ash, 2 parts of kuh-seng,
2 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 63 parts of rhizoma polygonati, 48 parts of Radix Ophiopogonis, 43 parts of aloe, 42 parts of Rhizoma Chuanxiong,
31 parts of honeysuckle, 26 parts of Chinese prickly ash, 3 parts of kuh-seng, 2 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 68 parts of rhizoma polygonati, 55 parts of Radix Ophiopogonis, 50 parts of aloe, 48 parts of Rhizoma Chuanxiong,
34 parts of honeysuckle, 26 parts of Chinese prickly ash, 2 parts of kuh-seng, 4 parts of ginseng；
Or, it is prepared by the bulk pharmaceutical chemicals of following parts by weight: 70 parts of rhizoma polygonati, 58 parts of Radix Ophiopogonis, 53 parts of aloe, 48 parts of Rhizoma Chuanxiong,
32 parts of honeysuckle, 27 parts of Chinese prickly ash, 3 parts of kuh-seng, 2 parts of ginseng.
5. a kind of method for preparing Chinese medicine composition described in Claims 1 to 4 any one, it is characterised in that: it include with
Lower step:
(1) raw material of each weight proportion is weighed；
(2) raw material mixed powder is broken, water heating extracting is distilled, is concentrated under reduced pressure, obtains extracting solution；
(3) by extracting solution it is cooling after, water extract-alcohol precipitation is concentrated under reduced pressure, it is dry to get.
6. according to the method described in claim 5, it is characterized by:
In the step (2), heating extraction is to add water to cook 2 times, and one decocts the distilled water for adding 10~12 times of amounts (v/w), impregnates
40min boils, and keeps slightly boiled 60min, filtering；Two decoct the distilled water for adding 10~12 times of amounts (v/w), boil, and keep slightly boiled and decoct
40min is boiled, is filtered, merging filtrate；
And/or in step (2), it is concentrated under reduced pressure as combined filtrate decompression is concentrated into relative density 1.03 at 60~70 DEG C
~1.06 medical fluid；
And/or in step (3), to be concentrated under reduced pressure to concentrate filtrate to relative density at 60~70 DEG C be 1.20~
1.30 clear cream；
And/or in step (3), dry is vacuum freeze drying or spray drying.
7. Chinese medicine composition described in Claims 1 to 4 any one has cleaning moisture-keeping function, skin care, right in preparation
Skin is non-stimulated, with skin repair effect, easy cleaning washing product in purposes；
Preferably, described that there is skin repair as improving skin gloss and compact degree, whitening, inhibit bacterium generation, antioxygen
Change, antipruritic, antiperspirant deodorization, softening skin, prevention and treatment sunburn, prevention and treatment dry skin, prevention and treatment acne, prevention and treatment scytitis.
8. purposes according to claim 7, it is characterised in that: the washing product is shower cream, body lotion, body are white,
Protection cream.
9. a kind of washing product, it is characterised in that: the washing product is to be with Chinese medicine composition described in Claims 1 to 4
Effective component, in addition daily chemicals field acceptable auxiliary material is prepared.
10. washing product according to claim 9, it is characterised in that: the washing product is shower cream, body lotion, body
Body frost, protection cream.
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| CN111214428A (en) * | 2020-03-02 | 2020-06-02 | 上海珈凯生物科技有限公司 | Traditional Chinese medicine extract composition with skin irritation resisting function and preparation method thereof |
| CN112057400A (en) * | 2020-09-15 | 2020-12-11 | 深圳市琉璃光生物科技有限公司 | Antiperspirant and preparation method thereof |
| WO2023278500A1 (en) * | 2021-06-30 | 2023-01-05 | The Procter & Gamble Company | Cleansing composition with pyrrolidone carboxylic acid |
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Application publication date: 20190920 |