CN1089585C - 左布比卡因在面部手术中的用途 - Google Patents

左布比卡因在面部手术中的用途 Download PDF

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Publication number
CN1089585C
CN1089585C CN98802994A CN98802994A CN1089585C CN 1089585 C CN1089585 C CN 1089585C CN 98802994 A CN98802994 A CN 98802994A CN 98802994 A CN98802994 A CN 98802994A CN 1089585 C CN1089585 C CN 1089585C
Authority
CN
China
Prior art keywords
levobupivacaine
surgery
administered
bupivacaine
block
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN98802994A
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English (en)
Chinese (zh)
Other versions
CN1249684A (zh
Inventor
B·A·金纳利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of CN1249684A publication Critical patent/CN1249684A/zh
Application granted granted Critical
Publication of CN1089585C publication Critical patent/CN1089585C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN98802994A 1997-03-03 1998-03-03 左布比卡因在面部手术中的用途 Expired - Lifetime CN1089585C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9704352.5 1997-03-03
GBGB9704352.5A GB9704352D0 (en) 1997-03-03 1997-03-03 Levobupivacaine and its use

Publications (2)

Publication Number Publication Date
CN1249684A CN1249684A (zh) 2000-04-05
CN1089585C true CN1089585C (zh) 2002-08-28

Family

ID=10808603

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98802994A Expired - Lifetime CN1089585C (zh) 1997-03-03 1998-03-03 左布比卡因在面部手术中的用途

Country Status (20)

Country Link
US (1) US5919804A (enExample)
EP (1) EP0981347B1 (enExample)
JP (1) JP2001513812A (enExample)
KR (1) KR100516676B1 (enExample)
CN (1) CN1089585C (enExample)
AT (1) ATE240730T1 (enExample)
AU (1) AU730390B2 (enExample)
BR (1) BR9808303A (enExample)
CA (1) CA2279497C (enExample)
DE (1) DE69814851T2 (enExample)
DK (1) DK0981347T3 (enExample)
ES (1) ES2199423T3 (enExample)
GB (1) GB9704352D0 (enExample)
HU (1) HU225151B1 (enExample)
IL (1) IL131084A0 (enExample)
NO (1) NO322446B1 (enExample)
PL (1) PL190900B1 (enExample)
PT (1) PT981347E (enExample)
WO (1) WO1998038996A1 (enExample)
ZA (1) ZA981779B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9802536A (pt) * 1997-07-21 1999-07-20 Darwin Discovery Ltd Método para anestesiar um paciente humano antes de cirurgias
ES2198731T3 (es) * 1997-07-22 2004-02-01 Darwin Discovery Limited Utilizacion de levobupivacaina.
ATE554748T1 (de) 1997-11-14 2012-05-15 Pacira Pharmaceuticals Inc Herstellung von multivesikulären liposomen
WO2000003660A1 (en) 1998-07-17 2000-01-27 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
WO2002096368A2 (en) * 2001-05-31 2002-12-05 Skyepharma Inc. Encapsulation of nanosuspensions in liposomes and microspheres
CA2493581C (en) * 2002-07-30 2014-12-23 Omeros Corporation Ophthalmologic irrigation solutions and method
DE10260313A1 (de) * 2002-12-20 2004-07-15 Siemens Ag Elektrische Maschine mit Wicklungen aus Litze
US20050176823A1 (en) * 2004-02-10 2005-08-11 Diaz Robert L. Intra-operative procedure for post-operative pain control
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI809304B (zh) 2014-12-01 2023-07-21 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
CN117979970A (zh) 2021-10-14 2024-05-03 帕西拉制药有限公司 布比卡因多囊脂质体制剂及其用途
US12070454B1 (en) 2022-05-05 2024-08-27 Pfof Llc Anesthetic nerve block and method
JP2025515641A (ja) 2022-05-05 2025-05-20 ピィーエフオーエフ エルエルシィー 麻酔の神経ブロックおよび製法
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12251468B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
GB9321061D0 (en) * 1993-10-13 1993-12-01 Chiroscience Ltd Analgestic agent and its use
CN1145483C (zh) * 1995-04-13 2004-04-14 达尔文发现有限公司 左旋丁哌卡因和它作为一个麻醉剂在孕妇中的作用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Also Published As

Publication number Publication date
WO1998038996A1 (en) 1998-09-11
DK0981347T3 (da) 2003-09-15
HUP0000873A2 (hu) 2000-09-28
CA2279497A1 (en) 1998-09-11
NO994257D0 (no) 1999-09-02
CN1249684A (zh) 2000-04-05
BR9808303A (pt) 2000-05-16
KR100516676B1 (ko) 2005-09-22
ATE240730T1 (de) 2003-06-15
DE69814851T2 (de) 2004-01-22
JP2001513812A (ja) 2001-09-04
NO322446B1 (no) 2006-10-09
AU6630498A (en) 1998-09-22
ZA981779B (en) 1999-03-03
HUP0000873A3 (en) 2002-10-28
HK1022651A1 (en) 2000-08-18
DE69814851D1 (de) 2003-06-26
PT981347E (pt) 2003-09-30
ES2199423T3 (es) 2004-02-16
EP0981347B1 (en) 2003-05-21
IL131084A0 (en) 2001-01-28
GB9704352D0 (en) 1997-04-23
PL190900B1 (pl) 2006-02-28
NO994257L (no) 1999-11-02
PL335561A1 (en) 2000-05-08
CA2279497C (en) 2009-01-20
AU730390B2 (en) 2001-03-08
KR20000075896A (ko) 2000-12-26
EP0981347A1 (en) 2000-03-01
HU225151B1 (en) 2006-07-28
US5919804A (en) 1999-07-06

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C06 Publication
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SE01 Entry into force of request for substantive examination
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GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20020828