CN1145483C - 左旋丁哌卡因和它作为一个麻醉剂在孕妇中的作用 - Google Patents
左旋丁哌卡因和它作为一个麻醉剂在孕妇中的作用 Download PDFInfo
- Publication number
- CN1145483C CN1145483C CNB961939435A CN96193943A CN1145483C CN 1145483 C CN1145483 C CN 1145483C CN B961939435 A CNB961939435 A CN B961939435A CN 96193943 A CN96193943 A CN 96193943A CN 1145483 C CN1145483 C CN 1145483C
- Authority
- CN
- China
- Prior art keywords
- levobupivacaine
- patient
- marcaine
- medicine
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Description
UBF(子宫血流量,ml/分钟) | |||
时 间 | LB | R | B |
0 | 457±139 | 451±118 | 466±121 |
30 | 453±127 | 453±119 | 472±113 |
60 | 450±136 | 467±119 | 469±127 |
Claims (3)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9507677.4 | 1995-04-13 | ||
GBGB9507677.4A GB9507677D0 (en) | 1995-04-13 | 1995-04-13 | Pharmaceutical formulation and dose |
US08/549,408 US5849763A (en) | 1993-10-13 | 1995-10-27 | Use of levobupivacaine as an anesthetic agent |
US08/549,408 | 1995-10-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1184426A CN1184426A (zh) | 1998-06-10 |
CN1145483C true CN1145483C (zh) | 2004-04-14 |
Family
ID=26306876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB961939435A Expired - Lifetime CN1145483C (zh) | 1995-04-13 | 1996-04-15 | 左旋丁哌卡因和它作为一个麻醉剂在孕妇中的作用 |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0821588B1 (zh) |
JP (1) | JPH11503444A (zh) |
CN (1) | CN1145483C (zh) |
AT (1) | ATE243036T1 (zh) |
AU (1) | AU704806B2 (zh) |
CA (1) | CA2216583C (zh) |
DE (1) | DE69628743T2 (zh) |
DK (1) | DK0821588T3 (zh) |
ES (1) | ES2201179T3 (zh) |
HK (1) | HK1012847A1 (zh) |
HU (1) | HU224226B1 (zh) |
MX (1) | MX9707875A (zh) |
NO (1) | NO318548B1 (zh) |
PL (1) | PL184052B1 (zh) |
PT (1) | PT821588E (zh) |
WO (1) | WO1996032109A2 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU694453B2 (en) * | 1993-10-13 | 1998-07-23 | Darwin Discovery Limited | Analgesic agent and its use |
US5849763A (en) * | 1993-10-13 | 1998-12-15 | Darwin Discovery Limited | Use of levobupivacaine as an anesthetic agent |
GB9704349D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
GB9704352D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
GB9704351D0 (en) * | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
WO1999004771A2 (en) * | 1997-07-21 | 1999-02-04 | Darwin Discovery Limited | Use of levobupivacaine |
US6432986B2 (en) | 1997-07-21 | 2002-08-13 | Bruce H. Levin | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
CA2294921C (en) * | 1997-07-22 | 2009-04-07 | Darwin Discovery Limited | Levobupivacaine and its use |
EP3331567B1 (en) | 2015-07-24 | 2020-09-23 | Neon Laboratories Ltd. | Stabilized injectable emulsion of propofol and ketamine |
WO2019226599A1 (en) * | 2018-05-22 | 2019-11-28 | Alkalidx, Inc. | Diagnostics and treatments of anesthetic insensitive subjects |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU694453B2 (en) * | 1993-10-13 | 1998-07-23 | Darwin Discovery Limited | Analgesic agent and its use |
GB9321061D0 (en) * | 1993-10-13 | 1993-12-01 | Chiroscience Ltd | Analgestic agent and its use |
-
1996
- 1996-04-15 AU AU53395/96A patent/AU704806B2/en not_active Expired
- 1996-04-15 CA CA002216583A patent/CA2216583C/en not_active Expired - Lifetime
- 1996-04-15 PL PL96322763A patent/PL184052B1/pl unknown
- 1996-04-15 EP EP96910087A patent/EP0821588B1/en not_active Expired - Lifetime
- 1996-04-15 WO PCT/GB1996/000912 patent/WO1996032109A2/en active IP Right Grant
- 1996-04-15 DE DE69628743T patent/DE69628743T2/de not_active Expired - Lifetime
- 1996-04-15 HU HU9900507A patent/HU224226B1/hu active IP Right Grant
- 1996-04-15 PT PT96910087T patent/PT821588E/pt unknown
- 1996-04-15 AT AT96910087T patent/ATE243036T1/de active
- 1996-04-15 JP JP8530831A patent/JPH11503444A/ja active Pending
- 1996-04-15 ES ES96910087T patent/ES2201179T3/es not_active Expired - Lifetime
- 1996-04-15 DK DK96910087T patent/DK0821588T3/da active
- 1996-04-15 CN CNB961939435A patent/CN1145483C/zh not_active Expired - Lifetime
- 1996-04-15 MX MX9707875A patent/MX9707875A/es unknown
-
1997
- 1997-10-10 NO NO19974708A patent/NO318548B1/no not_active IP Right Cessation
-
1998
- 1998-12-10 HK HK98113067A patent/HK1012847A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE243036T1 (de) | 2003-07-15 |
WO1996032109A3 (en) | 1997-02-13 |
HK1012847A1 (en) | 1999-08-13 |
AU5339596A (en) | 1996-10-30 |
HUP9900507A2 (hu) | 1999-06-28 |
DE69628743D1 (de) | 2003-07-24 |
CA2216583C (en) | 2007-10-30 |
EP0821588A2 (en) | 1998-02-04 |
JPH11503444A (ja) | 1999-03-26 |
HU224226B1 (hu) | 2005-06-28 |
DE69628743T2 (de) | 2004-05-13 |
ES2201179T3 (es) | 2004-03-16 |
EP0821588B1 (en) | 2003-06-18 |
PL184052B1 (pl) | 2002-08-30 |
MX9707875A (es) | 1997-11-29 |
WO1996032109A2 (en) | 1996-10-17 |
PT821588E (pt) | 2003-11-28 |
NO318548B1 (no) | 2005-04-11 |
CN1184426A (zh) | 1998-06-10 |
PL322763A1 (en) | 1998-02-16 |
HUP9900507A3 (en) | 1999-11-29 |
AU704806B2 (en) | 1999-05-06 |
DK0821588T3 (da) | 2003-07-28 |
NO974708D0 (no) | 1997-10-10 |
CA2216583A1 (en) | 1996-10-17 |
NO974708L (no) | 1997-12-10 |
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CN1145483C (zh) | 左旋丁哌卡因和它作为一个麻醉剂在孕妇中的作用 | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: Chirotech Technology Ltd. Applicant before: Chiroscience Limited |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: CHIROSCIENCE LTD. TO: CHIROTECH TECHNOLOGY LTD. |
|
ASS | Succession or assignment of patent right |
Owner name: DARWIN DISCOVERY LTD. Free format text: FORMER OWNER: CHIROTECH TECHNOLOGY LTD. Effective date: 20030403 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20030403 Address after: cambridge Applicant after: Darwin Discovery Ltd. Address before: cambridge Applicant before: Chirotech Technology Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CX01 | Expiry of patent term |
Granted publication date: 20040414 |
|
EXPY | Termination of patent right or utility model |