CN108884164B - 用于免疫疗法的经修饰细胞 - Google Patents

用于免疫疗法的经修饰细胞 Download PDF

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Publication number
CN108884164B
CN108884164B CN201780012682.XA CN201780012682A CN108884164B CN 108884164 B CN108884164 B CN 108884164B CN 201780012682 A CN201780012682 A CN 201780012682A CN 108884164 B CN108884164 B CN 108884164B
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cell
cells
gly
antibody
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CN108884164A (zh
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G·多蒂
E·兰多尼
A·沙姆谢夫
T·克雷兹施玛
M·德罗斯特
D·菲利普斯
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Cell Medica Switzerland AG
University of North Carolina at Chapel Hill
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Cell Medica Switzerland AG
University of North Carolina at Chapel Hill
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K35/14—Blood; Artificial blood
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K—PEPTIDES
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    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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CN201780012682.XA 2016-02-25 2017-02-24 用于免疫疗法的经修饰细胞 Expired - Fee Related CN108884164B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16020057 2016-02-25
EP16020057.2 2016-02-25
PCT/US2017/019301 WO2017147383A1 (en) 2016-02-25 2017-02-24 Modified cells for immunotherapy

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CN108884164A CN108884164A (zh) 2018-11-23
CN108884164B true CN108884164B (zh) 2022-12-27

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CN201780012682.XA Expired - Fee Related CN108884164B (zh) 2016-02-25 2017-02-24 用于免疫疗法的经修饰细胞
CN201780012727.3A Expired - Fee Related CN108699153B (zh) 2016-02-25 2017-02-24 Pd-l1的结合成员
CN202211150762.0A Pending CN116082505A (zh) 2016-02-25 2017-02-24 Pd-l1的结合成员

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US (3) US11434294B2 (enExample)
EP (3) EP4086285A1 (enExample)
JP (3) JP7080819B2 (enExample)
KR (2) KR20180111870A (enExample)
CN (3) CN108884164B (enExample)
AU (2) AU2017224843A1 (enExample)
BR (2) BR112018067696A2 (enExample)
CA (2) CA3014067A1 (enExample)
ES (1) ES2903408T3 (enExample)
RU (2) RU2018128462A (enExample)
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KR20180111870A (ko) * 2016-02-25 2018-10-11 셀 메디카 스위처란트 아게 Pd-l1에 대한 결합 성분
TW202408578A (zh) 2016-05-13 2024-03-01 美商再生元醫藥公司 藉由投予pd-1抑制劑治療皮膚癌之方法
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US11278570B2 (en) 2016-12-16 2022-03-22 B-Mogen Biotechnologies, Inc. Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
US11292842B2 (en) 2017-02-21 2022-04-05 Regeneron Pharmaceuticals, Inc. Anti-PD-1 antibodies for treatment of lung cancer
SG10202111394XA (en) 2017-04-13 2021-12-30 Senti Biosciences Inc Combinatorial cancer immunotherapy
JP2020517913A (ja) 2017-04-28 2020-06-18 ファイブ プライム セラピューティクス， インコーポレイテッド Ｃｄ８０細胞外ドメインポリペプチドによる治療方法
KR20250010750A (ko) * 2017-12-20 2025-01-21 포세이다 테라퓨틱스, 인크. Vcar 조성물 및 사용 방법
KR102795692B1 (ko) 2018-01-19 2025-04-16 밀테니 비오텍 비.브이. & 씨오. 케이지 키메라 항원 수용체를 발현하는 조절 t 세포
MX2020009116A (es) 2018-03-02 2020-12-07 Cdr Life Ag Proteinas triespecificas de union a antigenos.
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