CN108883231B - 附带容器的注射器 - Google Patents
附带容器的注射器 Download PDFInfo
- Publication number
- CN108883231B CN108883231B CN201780020459.XA CN201780020459A CN108883231B CN 108883231 B CN108883231 B CN 108883231B CN 201780020459 A CN201780020459 A CN 201780020459A CN 108883231 B CN108883231 B CN 108883231B
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- syringe
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- nozzle
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Abstract
本发明的一形态提供一种将预充式注射器收容在容器中的附带容器的注射器,所述预充式注射器包括筒状的注射器主体及活塞,注射器主体中充填有具有发泡性的材料,活塞的一端侧被压入所述注射器主体的内部,所述容器具有主体收容部及活塞收容部,主体收容部以沿着所述注射器主体的形状凹陷的方式形成,用于收容所述注射器主体,活塞收容部以沿着所述活塞的形状凹陷的方式形成,用于收容所述活塞,沿着所述预充式注射器的軸方向,所述活塞收容部的长度小于所述活塞的长度。
Description
技术领域
本发明涉及一种附带容器的注射器。
背景技术
目前已有牙齿漂白用组成物,通过包含氧化氢或过氧化氢衍生物来提高牙齿漂白效果(例如,参照专利文献1)。从使用时的简便性及防污染等观点出发,通常将这种牙齿漂白用组成物预先充填在例如具有注射器主体、活塞的注射器内的状态提供给用户。
预先充填有牙齿漂白用组成物之类的药剂的注射器被称为预充式注射器,以附带容器的的状态被投入流通。
现有技术文献
专利文献
专利文献1:日本特开2009-242290号公报
发明内容
发明要解决的问题
在此,例如上述过氧化氢或过氧化氢衍生物分解而产生了过氧化氢的分解物的气泡时,注射器主体的内压提高,有时活塞会向着脱离注射器主体的方向变位。若发生这种活塞变位,可能会导致活塞脱离注射器主体而发生药剂泄漏、注射器脱离容器而破损、无法作为预充式注射器使用。
本发明的一个形态,是鉴于上述问题进行研发的成果,其目的在于提供一种可抑制活塞变位的附带容器的注射器。
用于解决问题的手段
本发明的一形态提供一种将预充式注射器收容在容器中的附带容器的注射器,所述预充式注射器包括筒状的注射器主体及活塞,注射器主体中充填有具有发泡性的材料,活塞的一端侧被压入所述注射器主体的内部,所述容器包括主体收容部及活塞收容部,主体收容部以沿着所述注射器主体的形状凹陷的方式形成,以收容所述注射器主体,活塞收容部以沿着所述活塞的形状凹陷的方式形成,以收容所述活塞,沿着所述预充式注射器的軸方向,所述活塞收容部的长度小于所述活塞的长度。
发明的效果
根据本发明的一个形态,提供一种可抑制活塞变位的附带容器的注射器。
附图说明
图1是例示本实施方式的附带容器的注射器的平面图。
图2是例示本实施方式的附带容器的注射器的正面图。
具体实施方式
以下,关于本发明的实施方式,根据附图进行说明。在各附图中,对同一构成部分采用同一符号,有时省略重复说明。
图1及图2例示了本实施方式的附带容器的注射器。
附带容器的注射器1的结构如图1及图2所示,预充式注射器10被收容在容器20中。
预充式注射器10具有喷嘴110、注射器主体120及活塞140。喷嘴110、注射器主体120及活塞140例如由塑料(plastic)形成。注射器主体120中充填有牙齿漂白用组成物121。预充式注射器10的使用者,通过将活塞140推入注射器主体120中,从注射器主体120挤出牙齿漂白用组成物121,而能够从喷嘴110的吐出口吐出牙齿漂白用组成物121。
喷嘴110被设置在注射器主体120的一端。喷嘴110在与注射器主体120为相反侧的端部具有吐出口,用于吐出从注射器主体120被挤出的牙齿漂白用组成物121。当预充式注射器10被收容在容器20中时,或不使用预充式注射器10时,如图1及图2所示,在喷嘴110上套上用于封堵吐出口的帽111。
注射器主体120为圆筒状,其内部充填有牙齿漂白用组成物121。注射器主体120的一端设有喷嘴110,另一端的开口供活塞140插入。在注射器主体120的与喷嘴110为相反侧的端部,形成有向外侧突出的檐状的突缘130。
活塞140为柱状,一端侧被插入注射器主体120内。在活塞140的被插入到注射器主体120内的侧的端部,设有衬垫141。衬垫141例如由橡胶等树脂材料形成,用于密封注射器主体120的内部空间。活塞140被压入到注射器主体120的内部时,被衬垫141挤出的牙齿漂白用组成物121将从喷嘴110吐出。
在此,牙齿漂白用组成物121是充填在预充式注射器10的注射器主体120中的材料的一个例子。牙齿漂白用组成物121,例如被涂敷附着于牙齿上,对有色素沉着的牙齿进行漂白。
在此,充填在预充式注射器10中的材料,只要是具有发泡性的材料,并不限定于牙齿漂白用组成物121。
牙齿漂白用组成物121包含过氧化氢或过氧化氢衍生物,还优选包含增稠剂、溶媒。
过氧化氢或过氧化氢衍生物具有漂白作用。
作为过氧化氢衍生物,例如可以举出过氧化脲(urea peroxide)、过硼酸盐(perborate)、过碳酸盐(percarbonate)、过磷酸盐、过硫酸盐类、过氧化钙、过氧化镁、过氧化氢聚乙烯吡咯烷酮(Polyvinylpyrrolidone)等。作为过氧化氢衍生物优选使用过氧化脲。
牙齿漂白用组成物121因包含过氧化氢或过氧化氢衍生物,过氧化氢的分解物产生气泡,而成为具有发泡性的材料。
牙齿漂白用组成物121中的过氧化氢或过氧化氢衍生物的含量,换算成过氧化氢的量,优选为1质量%~30质量%。牙齿漂白用组成物121中的过氧化氢或过氧化氢衍生物的含量为1质量%以上时,容易获得牙齿漂白用组成物121的漂白効果,30质量%以下时,可以提高牙齿漂白用组成物121的保存稳定性。
作为增稠剂,例如可以举出,羧甲基纤维素钠(Sodium carboxyl cellul ose)、海藻酸钠(Sodium alginate)、海藻酸丙二醇酯(Propylene glycol a lginate)、聚羧乙烯(Carboxy polymethylene)、羧甲基纤维素(Carboxy methyl cellulose)、羧甲基纤维素钠(Carboxy methylcellulose sodium)、羧甲基纤维素钙(Carboxy methyl-cellulosecalcium)、甲基乙烯基醚(Met hyl vinyl ether)/马来酸酐(maleic anhydride)共聚物、二甲聚硅氧烷(Di methylpolysiloxane)、羧甲基淀粉钠(Sodium starch glycolate)、淀粉磷酸酯钠(Sodium starch phosphate)、聚丙烯酸钠(Sodium polyacrylate)、甲基纤维素(Methyl cellulose)、羟甲基纤维素(Hydroxy methyl cellulose)、羟乙基纤维素(Hydroxy ethyl cellulose)、羟丙基纤维素(Hydroxy propyl cellulose)、聚乙烯吡咯烷酮(Polyvinyl pyrrolidone)、丙烯酸/山嵛酸(be henic acid)共聚物、结晶纤维素等有机增稠剂类;瓜尔胶(Guar gum)、槐豆胶(Carob bean gum)、塔拉胶(Tara gum)、罗望子胶(Tamarind seed gum)、阿拉伯树胶(Gum arabic)、黄蓍胶(Gum tragacanth)、卡拉牙胶(Karaya gum)、海藻酸(Alginic acid)、卡拉胶(carrageenan)、黄原胶(Xanthan gum)、结兰胶(Gellan gum)、可德胶(Curdlan,凝胶多糖)、几丁质(甲壳素,Chitin)、几丁聚糖(壳聚糖,Chitosan)、壳糖胺(Chitosamine)等天然增稠剂;碳酸钙、硅酸钙、硅酸镁、硅酸镁钙、硅酸钠镁锂、硅粉、各种玻璃类、非晶质含水硅酸、气相二氧化硅(fumed silica)等无机增稠剂类。作为增稠剂,优选使用聚乙烯吡咯烷酮、聚羧乙烯、甲基乙烯基醚/马来酸酐共聚物。
牙齿漂白用组成物121中的增稠剂的含量优选为0.5质量%~30质量%。牙齿漂白用组成物121中的增稠剂的含量为0.5质量%以上时,牙齿漂白用组成物121的粘度提高,而容易附着在牙齿上。另外,牙齿漂白用组成物121中的增稠剂的含量为30质量%以下时,牙齿漂白用组成物121变软,容易从注射器主体120中挤出牙齿漂白用组成物121。
作为溶媒,可以使用水及/或酒精(alcohol)。
另外,作为酒精,考虑到对牙齿的附着操作性,优选使用乙醇、硬脂醇、1-丙醇、2-丙醇、2-甲基-2-丙醇、聚乙二醇单甲醚(Polyethylene glycol mon omethylether)、多元醇。
作为多元醇,考虑到良好的安全性、与牙齿的亲和性,优选使用甘油(Glycerine)、二甘油(Diglycerine)等聚甘油(Polyglycerine)、乙二醇(Ethylene glycol))、二乙二醇(Diethylene glycol)、聚乙二醇(Polyethylene glycol)、丙二醇(Propylene glycol)、二丙二醇(Dipropylene glycol)、聚丙二醇(Polypropylene glycol)、1,2-戊二醇(1,2-pentanediol)、1,2-己二醇(1,2-hexanediol)、1,2-辛二醇(1,2-octanediol)、山梨醇(Sorbitol)、甘露醇(Mannitol)或这些的混合物。
作为溶媒优选使用水及/或多元醇,作为多元醇优选使用甘油、聚乙二醇、丙二醇。
牙齿漂白用组成物121中的溶媒含量优选为50质量%~85质量%。牙齿漂白用组成物121中的溶媒含量为50质量%以上时,牙齿漂白用组成物121会变软,容易从注射器主体120挤出牙齿漂白用组成物121。另外,牙齿漂白用组成物121中的溶媒含量为85质量%以下时,可提高牙齿漂白用组成物121的保存稳定性。
此外,牙齿漂白用组成物121中,除了过氧化氢或过氧化氢衍生物、增稠剂、溶媒之外,还可以包含例如、氧化钛、酸化亜鉛、氮氧化钛等金属氧化物、参杂氮的氧化钛、金属盐、金属粉末、用于使过氧化氢活性化的催化剂、钙螯合剂、pH调整剂等。
容器20例如使用塑料(plastic)薄片,成型为底面开放的箱形,注射器收容部200、冲击吸收部201及凹部202分别被形成为从上面凹陷的形状。另外,容器20还可以具有用于覆盖被放置在注射器收容部200中的预充式注射器10的盖子。
沿着预充式注射器10的形状,以从容器20的上面凹陷的方式形成注射器收容部200,用于放置预充式注射器10。
在与注射器收容部200不同的位置,以从容器20的上面凹陷的方式形成冲击吸收部210,其用于吸收例如附带容器的注射器1掉落时的冲击或搬运附带容器的注射器1时的振动等,从而防止预充式注射器10的破损。
如图2所示,在预充式注射器10的注射器主体120的軸方向的中央附近,以从容器20的上面凹陷的方式形成有凹部202。由此,预充式注射器10的使用者,通过握持注射器主体120,容易从容器20中取出预充式注射器10。
此外,附带容器的注射器1中,容器20上形成有2个注射器收容部200,然而容器20上形成的注射器收容部200的个数并不限定于2个。
在此,图1中为了展示注射器收容部200的形状,显示了从一个注射器收容部200中取出预充式注射器10后的状态。
另外,冲击吸收部201及凹部202的形状、位置、个数等的构成方式并不限定于图1及图2所例示的结构。
注射器收容部200包括喷嘴收容部210、主体收容部220、突缘收容部230及活塞收容部240。
喷嘴收容部210以沿着预充式注射器10的喷嘴110及帽111的形状的方式,形成从容器20的上面凹陷的半圆筒状。喷嘴收容部210用于收容带有帽111的喷嘴110。
主体收容部220以沿着预充式注射器10的注射器主体120的形状的方式,形成从容器20的上面凹陷的半圆筒状。主体收容部220用于收容预充式注射器10的注射器主体120。
突缘收容部230以沿着预充式注射器10的注射器主体120上设有的突缘130的形状的方式,形成从容器20的上面凹陷的半圆筒状。突缘收容部230用于收容预充式注射器10的突缘130。
活塞收容部240以沿着预充式注射器10的活塞140的形状的方式,形成从容器20的上面凹陷的半圆筒状。活塞收容部240用于收容预充式注射器10的活塞140。
喷嘴收容部210、主体收容部220、突缘收容部230及活塞收容部240分别迎合预充式注射器10的各部分的形状,进深(图1中的左右方向的宽度)及始于上面的深度相异。
被收容在注射器收容部200的预充式注射器10,其注射器主体120被深度相异的喷嘴收容部210及主体收容部220之间的阶差所卡止,因此可限制该被收容在注射器收容部200中的预充式注射器10沿着軸方向(图1及图2中的上下方向)朝向喷嘴110侧发生变位。另外,预充式注射器10,其突缘130被突缘收容部230卡止,因此可抑制该被收容在注射器收容部200的预充式注射器10沿着軸方向发生变位。
另外,沿着被收容在注射器收容部200的预充式注射器10的軸方向,活塞收容部240的长度Lc小于活塞140(包含衬垫141)的长度Lp。
在此,充填在注射器主体120中的牙齿漂白用组成物121,例如,因过氧化氢衍生物经时分解或过氧化氢衍生物被加热分解而生成的分解物导致产生气泡,使注射器主体120的内压增大,有时会将活塞140推至喷嘴110的相反侧。
在此情况下,因活塞收容部240的长度Lc小于活塞140的长度Lp,在活塞140脱离注射器主体120之前,衬垫141的相反侧的端部就会接触到活塞收容部240的壁面240a。另外,因注射器主体120及突缘130被注射器收容部200卡止,预充式注射器10沿着活塞140的軸方向的变位受到限制,基本被固定。
根据上述结构,例如,即使在牙齿漂白用组成物121因发泡而推压活塞140的情况下,活塞140脱离注射器主体120之前,端部就会接触到活塞收容部240的壁面240a,而不会有进一步的变位。如上所述,因活塞140沿着軸方向的变位受到限制,因此可降低活塞140从注射器主体120脱落、预充式注射器10从容器20脱落等问题的发生。
如上所述,根据附带容器的注射器1,即使在被充填在注射器主体120中的牙齿漂白用组成物121发泡的情况下,也能够抑制活塞140沿着軸方向发生变位。因此,能够降低活塞140沿着軸方向发生变位的不良问题的发生。
以上说明了本实施方式的附带容器的注射器,但本发明并不限定于上述实施方式,在本发明的范围内可进行各种变更及改良。
本国际申请根据2016年3月31日提出的日本国专利申请2016-071321请求优先权,并且,本国际申请引用日本国专利申请2016-071321的所有内容。
附图标记说明
1 附带容器的注射器
10 预充式注射器
20 容器
110 喷嘴
120 注射器主体
121 牙齿漂白用组成物
130 突缘
140 活塞
200 注射器收容部
210 喷嘴收容部
220 主体收容部
230 突缘收容部
240 活塞收容部
Claims (5)
1.一种将预充式注射器收容在容器内的附带容器的注射器,其特征在于,
所述预充式注射器包括:
筒状的注射器主体,充填有具有发泡性的材料,
喷嘴,设置于所述注射器主体的一端,以及
活塞,所述活塞的一端侧被压入所述注射器主体内部,
所述容器具有:
主体收容部,以沿着所述注射器主体的形状凹陷的方式形成,用于收容所述注射器主体,
喷嘴收容部,以沿着所述喷嘴的形状凹陷的方式形成,用于收容所述喷嘴,以及
活塞收容部,以沿着所述活塞的形状凹陷的方式形成,用于收容所述活塞,
沿着所述预充式注射器的轴方向,所述活塞收容部的长度小于所述活塞的长度,
所述预充式注射器的所述注射器主体被所述喷嘴收容部及深度比所述喷嘴收容部深的所述主体收容部之间的阶差所卡止,从而,限制被收容在所述容器中的所述预充式注射器沿着轴方向朝向所述喷嘴侧的变位。
2.根据权利要求1所述的附带容器的注射器,其特征在于,
在所述注射器主体形成有突缘,
所述容器具有突缘收容部,所述突缘收容部以沿着所述突缘的形状凹陷的方式形成,用于收容所述突缘。
3.根据权利要求1所述的附带容器的注射器,其特征在于,
所述具有发泡性的材料包含过氧化氢或过氧化氢衍生物。
4.根据权利要求3所述的附带容器的注射器,其特征在于,
所述具有发泡性的材料还包含增稠剂及溶媒。
5.根据权利要求4所述的附带容器的注射器,其特征在于,
所述具有发泡性的材料中,所述过氧化氢或过氧化氢衍生物的含量按换算成过氧化氢的量为1质量%~30质量%,所述增稠剂的含量为0.5质量%~30质量%,所述溶媒的含量为50质量%~85质量%。
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WO2020100525A1 (ja) * | 2018-11-16 | 2020-05-22 | 株式会社Kortuc | 過酸化水素溶液に適したシリンジ及びキット |
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