CN108566947A - A kind of foam disinfectant auxiliary agent, preparation method and foamaseptic prepared therefrom - Google Patents
A kind of foam disinfectant auxiliary agent, preparation method and foamaseptic prepared therefrom Download PDFInfo
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- CN108566947A CN108566947A CN201710142669.8A CN201710142669A CN108566947A CN 108566947 A CN108566947 A CN 108566947A CN 201710142669 A CN201710142669 A CN 201710142669A CN 108566947 A CN108566947 A CN 108566947A
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- disinfectant
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/16—Foams
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
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- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A kind of foam disinfectant auxiliary agent of present invention offer, preparation method and foamaseptic prepared therefrom, wherein containing quaternary surfactant, tackifier and stabilizer in the foam disinfectant auxiliary agent.Foam disinfectant auxiliary agent through the invention enables to the foam of disinfectant to hold time up to 30 45min, and foam disinfectant auxiliary agent can be in low dilution (1:1000) effective under acting on, foamaseptic has preferable stability, without cleaning after use, natural drying, greatly reduce the pollution to environment, it can be to livestock and poultry cultivation place, poultry house utensil, especially to having band rill, having mesh, in quick, thorough, the effective disinfection of the complicated body surface progress such as paliform.
Description
Technical field
The invention belongs to field of fine chemical, and in particular to a kind of foam disinfectant auxiliary agent, preparation method and by its system
Standby foamaseptic.
Background technology
The column home of livestock and poultry contact stain be infectious disease important channel, thoroughly cleaning and disinfection column home to epidemic preventing sanitary extremely
It closes important.The environmental sanitation situation several diseases larger to livestock birds health growth effect have：Colibacillosis, atrophic rhinitis,
Contagious pleuropneumonia, mammitis etc., it is therefore necessary to all contain cause of disease parasitic animal and plant and parasitic surface (means of transport,
Use article, poultry house place, obstetric table etc.) carry out cleaning-sterilizing, by effective cleaning and disinfection to be greatly decreased respiratory tract,
The diseases such as enteron aisle have great importance.
Traditional cleaning-sterilizing mode includes that machinery is rooted out, flame calcination, giant the methods of rinse at present, is then made
With quaternary ammonium salt (such as Deciquam, last of the ten Heavenly stems Matsubain), Operand (povidone iodine, acid iodide), organic chlorinated product (dichloroisocyanuric acid
Sodium, trichloroisocyanuric acid), the disinfectants such as caustic soda are sprayed or are splashed disinfection.But there is larger drawback, such as labor in these methods
Fatigue resistance is excessive, and the cleaning-sterilizing time is long, and cleaning effect is not thorough, and water resource waste is serious, and using caustic soda to equipment, column home
With human body, carcass corrosivity is too big the problems such as.It of particular concern is the bacterium in animal house with virus usually with biomembrane
Form is grown and breeding, and can regulate and control its physiological behavior according to population effect, escapes to conventional disinfectant and adverse circumstances generation
It keeps away and tolerance, there is very strong resistance；Therefore general cleaning and disinfectant measure cannot be killed effectively and be present in biology
Bacterium, virus in film, the generation of the various pathogenic bacteria of survival to the respiratory tract of next group livestock and poultry, alimentary canal and reproductive disease
Bring great risk.Therefore with the raising of cultivation large-scale degree, how within a short period of time to obstetric table, empty column, apparatus, field
The progress such as ground, which effectively, are thoroughly cleaned and sterilized, has become traditional cleaning-sterilizing mode problem in the urgent need to address.
Foam type cleaning and sterilizing agent is a kind of novel product, is to be formed by disinfectant and foam disinfectant auxiliary combination, and lead to
It crosses related foam device and converts the cleaning and sterilizing agent of liquid to gas phase form of foam, foam directly connects with disinfecting surface to be cleaned
After touch by mode the effects that wetting, emulsification, infiltration, dispersion and solubilising, grease, protein, dirt, the biomembrane on surface are removed
Deng to achieve the purpose that while clean and disinfection.Compared with common cleaning and sterilizing mode, foamaseptic Disinfection Effect has
Following advantages：1. sterilizing good：Foamaseptic and pathogen extended durations of action, especially band rill have mesh, are in paliform
Etc. complicated body surface, Disinfection Effect is more preferably；2. more thoroughly：Foam disinfectant is visual, avoids disinfection blind area, disinfection is more
Uniformly, thoroughly；3. water-saving saves medicine：Disinfectant caused by reducing high-pressure fog repeats sprinkling and the waste of water；4. corrosion-free：To cage
Tool and equipment are not corroded；5. people is harmless：Reduce the liquid soakage of operating personnel.
But the stability of foamaseptic at present on the market is poor, and decontaminant concentration is higher, disinfection is left later
Residuals not easy cleaning, can cause damages to the health of poultry.
Invention content
Present invention solves the technical problem that being:The stability for improving foamaseptic, reduces decontaminant concentration, overcomes
Disinfection residual harm caused by poultry later, can be to livestock and poultry cultivation place, poultry house utensil, especially to tool band ditch
Line has mesh, carries out quick, thorough, effective disinfection in the complicated body surface such as paliform.
To solve the deficiencies in the prior art, the purpose of the present invention is to provide a kind of foam disinfectant auxiliary agent, the foam disappears
Contain quaternary surfactant 40-80% (W/V), tackifier 0.1-1.5% (W/V), stabilizer 0.5-2% in malicious auxiliary agent
(W/V)。
Another object of the present invention is to provide a kind of preparation methods of above-mentioned foam disinfectant auxiliary agent, including following step
Suddenly：
1) quaternary surfactant is weighed in the ratio of whole content 40%-80%W/V, suitable water, heating is added to make it
Dissolving；
2) stabilizer is weighed in the ratio of whole content 0.5-2%W/V, a small amount of water is added, be gradually heated to 80 DEG C, keep temperature
Degree stirring 20min, until it is completely dissolved；And
3) tackifier of complete stabilizer and whole content 0.1-1.5%W/V, essence will be dissolved in step 2), cleaning helps
Agent is mixed evenly with liquid in step 1), waits for liquid cooled to room temperature, adjusts pH value to about 7.0, adds suitable quantity of water constant volume,
Up to the foam disinfectant auxiliary agent.
It is still another object of the present invention to provide a kind of foamaseptic, the foamaseptic includes of the present invention
Foam disinfectant auxiliary agent and disinfectant.
It is still another object of the present invention to provide a kind of foam disinfectant auxiliary agent of the present invention or the foam disinfectants
The application of agent, which is characterized in that the foam disinfectant auxiliary agent or the foamaseptic be applied to livestock and poultry cultivation place,
Poultry house utensil, especially to having with rill, having mesh, in the disinfection of the complicated body surface such as paliform.
The advantageous effect that technical solution of the present invention is brought：
Realize disinfection rapidly and efficiently：Disinfectant is become foam by foam disinfectant auxiliary agent, is sprayed on the object tables such as wall, utensil
Face, foam are sticked to body surface and do not flow down；And foam is multiple overlapping, substantially prolongs disinfectant and is sterilized body surface
Time of contact (disinfectant foam is held time up to 30-45min), thus with pathogen extended durations of action, especially with ditch
Line has mesh, in the complicated body surface such as paliform, compared with simple disinfectant, disinfection more rapidly, it is better.
Disinfection is more thorough：It is visual strong when the addition of foam disinfectant auxiliary agent makes disinfection, avoid disinfection blind area, disinfection more equal
It is even, thorough；
It can be used under the conditions of dilution for many times：It is not required to clean, natural drying, residue is to poultry fanout free region, to ring
Border pollution is small.
Stability is strong：Foamaseptic has stronger stability, and foam length of holding time.
Water-saving saves medicine：Disinfectant caused by reducing high-pressure fog repeats sprinkling and the waste of water, without cleaning after use, from
It is so dry, greatly reduce the pollution to environment.
It is non-corrosive：Without alkaline matter, the problems such as corroding will not be generated to equipment, column home and human body, carcass.
Specific implementation mode
The purpose of the present invention is to provide a kind of foam disinfectant auxiliary agent, quaternary ammonium salt surface is contained in the foam disinfectant auxiliary agent
Activating agent 40-80% (W/V), tackifier 0.1-1.5% (W/V), stabilizer 0.5-2% (W/V).
Preferably, each component of foam disinfectant auxiliary agent according to the present invention and each component content be for：
As without particularly pointing out, W/V is kg/L.Wherein percentage indicates the grams containing the ingredient in 100ml solution.It is more excellent
Selection of land, each component and each component content of foam disinfectant auxiliary agent according to the present invention are：
Preferably, quaternary surfactant of the present invention is benzalkonium bromide or benzalkonium chloride.
Principal component benzalkonium bromide or benzalkonium chloride are a kind of cation surface activatings in foam disinfectant auxiliary agent of the present invention
Agent, soluble easily in water, transparent solution have good foamability.The additionally ability with sterilizing, it is stingless to skin
Swash, it is non-toxic, metal is not corroded, property is relatively stablized, even if also stablizing in boiling water.
Preferably, tackifier of the present invention are dodecyldimethylamine oxide, empgen BB, dodecyl
One in ethyoxyl sulfobetaines, myristamide propyl hydroxypropyl sulfobetaines, octadecyl dihydroxy ethyl amine-oxides
Kind is several.
One of the present invention significantly has the technical effect that by the way that such as dodecyldimethylamine oxide or dodecyl is added
The tackifier of glycine betaine enable foam disinfectant auxiliary agent to generate strength stickiness and abundant foam.This tackifier is amphoteric ion
Surfactant has good thickening, antistatic, soft, foam enhancing performance；Scourability is excellent, foaming abundancy is stablized, blistering
The tackifier of the remote unconventional such as coconut oil diethanol amide 6501 of ability.
Preferably, stabilizer of the present invention is Arabic gum, mosanom, xanthans, laruyl alcohol, lauroyl diethanol amine
One or more of.
Preferably, cleaning additive of the present invention is four sodium of iminodisuccinic acid.
Of the invention another significantly has the technical effect that four sodium of cleaning additive iminodisuccinic acid be added is a kind of life
State environment-friendly type complexing agent, it is easily biological-degradable, nontoxic to the ecosystem；Compatibility is excellent, to manganese, calcium, zinc and other transition
The chelating ability of metal ion is suitable with EDTA, especially splendid to iron, copper metal ion chelating ability, is more than the chelating ability of EDTA；Clearly
Hard surface is washed to be used together with surfactant, can to band rill, have mesh, in the complicated object such as paliform
Play extraordinary cleaning performance in surface.
Preferably, pH adjusting agent of the present invention is phosphoric acid or acetic acid.
As a kind of further preferred embodiment of the present invention, each component and each component content of the foam disinfectant auxiliary agent
For：
Or
Or
Or
The foam disinfectant auxiliary agent of the present invention, property are stablized, and have strength stickiness, foaming capacity is strong and stablizes, and has extremely strong
Dirt penetrating power, solution, which is neutrality, non-corrosive, Environmental Safety, and dilution for many times (1000 times), still has preferable hair
Bubble ability.
Another object of the present invention is to provide a kind of preparation methods of above-mentioned foam disinfectant auxiliary agent, including following step
Suddenly：
1) quaternary surfactant is weighed in the ratio of whole content 40%-80%W/V, suitable water, heating is added to make it
Dissolving；
2) stabilizer is weighed in the ratio of whole content 0.5-2%W/V, a small amount of water is added, be gradually heated to 80 DEG C, keep temperature
Degree stirring 20min, until it is completely dissolved；And
3) tackifier of complete stabilizer and whole content 0.1-1.5%W/V, essence will be dissolved in step 2), cleaning helps
Agent is mixed evenly with liquid in step 1), waits for liquid cooled to room temperature, adjusts pH value to about 7.0, adds suitable quantity of water constant volume,
Up to the foam disinfectant auxiliary agent.
It is still another object of the present invention to provide a kind of foamaseptic, the foamaseptic includes of the present invention
Foam disinfectant auxiliary agent and disinfectant.
Preferably, after the foamaseptic is diluted to 50~1000 times by the foam disinfectant auxiliary agent, with the disinfection
Agent presses 1:1~1:10 ratio mixing composition.
It is highly preferred that after the foamaseptic is diluted to 50~1000 times by the foam disinfectant auxiliary agent, disappear with described
Toxic agent presses 1:5 ratio mixing composition.
Preferably, the disinfectant is glutaraldehyde benzalkonium bromide, Iodophor, povidone iodine, bleaching powder, sodium hypochlorite, dioxy
Change at least one of chlorine, Peracetic acid and hydrogen peroxide.
It is still another object of the present invention to provide a kind of foam disinfectant auxiliary agent of the present invention or the foam disinfectants
The application of agent, which is characterized in that the foam disinfectant auxiliary agent or the foamaseptic are mainly used in livestock and poultry cultivation
Place, poultry house utensil, especially to having with rill, having mesh, in the disinfection of the complicated body surface such as paliform.
The present invention is specifically described with reference to specific embodiment, but is not intended to limit present disclosure.
Embodiment 1：
Foam disinfectant auxiliary agent prescription of the present invention and preparation method
Sample 1
Preparation method is as follows：
1) 40 grams of benzalkonium bromide is weighed, is placed in glass container, suitable water, heating water bath is added to make it dissolve；
2) 0.5 gram of Arabic gum is weighed, a small amount of water is added, 80 DEG C are gradually heated under water bath condition, temperature is kept to stir
20min is mixed, until it is completely dissolved；And
3) by the complete Arabic gum of dissolving in step 2) and 0.1 gram of dodecyldimethylamine oxide, flavoring apple essence 1.0
Gram, solution is mixed evenly in 1 gram of four sodium of iminodisuccinic acid and step 1), waits for liquid cooled to room temperature, adds
When water is to close to 100ml, appropriate pH adjusting agent tune pH value is added to about 7.0 (being controlled with pH meter), water is added to be settled to 100ml.
Bottling is to get the foam disinfectant auxiliary agent.
Sample 2
Preparation method is as follows：
1) 40 grams of benzalkonium chloride is weighed, is placed in glass container, suitable water, heating water bath is added to make it dissolve.
2) 0.5 gram of Arabic gum is weighed, 80 DEG C are gradually heated under water bath condition, temperature is kept to stir 20min, until its
It is completely dissolved.
3) by the complete Arabic gum of dissolving in step 2) and 0.1 gram of dodecyldimethylamine oxide, flavoring apple essence 1.0
Gram, solution is mixed evenly in 1 gram of four sodium of iminodisuccinic acid and step 1), waits for liquid cooled to room temperature, adds
When water is to close to 100ml, appropriate pH value adjustment agent tune pH value is added to about 7.0 (being controlled with pH meter), water is added to be settled to 100ml.
Bottling is to get the foam disinfectant auxiliary agent.
Other prescriptions prepare gained foam disinfectant auxiliary agent and are shown in Table 1.
1. other prescriptions of foam disinfectant auxiliary agent of the present invention of table
Other contents and preparation method are the same as sample 1, sample 2 in prescription.
Embodiment 2：
The preparation of foamaseptic
It (is usually 50~1000 that a certain amount of water of foam disinfectant auxiliary agent prepared by embodiment 1, which is matched into a certain concentration,
Solution is uniformly mixed with disinfectant with certain proportion compatibility again), you can foamaseptic is made.The disinfectant is glutaraldehyde benzene
It pricks in bromine ammonium salt solution, Iodophor, povidone iodine, bleaching powder, sodium hypochlorite, chlorine dioxide, Peracetic acid and hydrogen peroxide at least
It is a kind of.
Preferably, disinfectant is glutaraldehyde benzalkonium bromide solution.Preferably, disinfectant and foam disinfectant additive compatibility ratio
It is 5:1
Compatibility prepares gained each prescription of foamaseptic and is shown in Table 2.
2. foamaseptic prescription of the present invention of table
Embodiment 3：
The evaluation of foamaseptic
Since this laboratory condition limits, we carry out commenting for foamaseptic using improvement Warring Blender methods
Valence.Foamaseptic 9,10,11, the 12 4 each 100ml of prescription obtained by the present invention are taken, 30min is quickly stirred, uses magnetic force
Blender most high speed stirring (rotating speed 800-1200 turn/min), every time at the end of there are about 50ml liquid not at foam-like, by foam
And liquid all pours into graduated cylinder, (i.e. liquid is precipitated to quarter in foam for observation foam volume (including liquid volume) and half foam life period
The time required to spending 100ml).Test result see the table below.
3 foamaseptic foam volume of table and half-life period investigate result
| Lot number | Foam volume (ml) | Half foam life period (min) |
| Prescription 9 | 589 | 38 |
| Prescription 10 | 578 | 42 |
| Prescription 11 | 543 | 35 |
| Prescription 12 | 592 | 37 |
By result it can be seen that：The foam volume that the foamaseptic sample of tetra- prescriptions of 100ml can be generated is all higher than
The half-life period of 500ml, foam are all higher than 30min, illustrate that this foamaseptic frostproof froth n ability is strong, hold time long.
Embodiment 4：
The long-term stable experiment of foamaseptic
4.1. classical isothermal method predicts the term of validity
Take foamaseptic 9,10,11,12 4 prescriptions obtained by the present invention, be respectively put into 90 DEG C, 85 DEG C, 80 DEG C,
70 DEG C of 4 temperature are primary every 1h samplings, measure the content of quaternary ammonium salt in foamaseptic 4, and last time sample time is
10h.According to the situation of change of quaternary ammonium salt content, the temperature and decomposition rate equation of change of each sample are listed, when finding out 25 DEG C
The term of validity.
Classical isothermal method predicts, the term of validity of prescription 9,10,11,12 is respectively 2.58,2.31,2.42,2.23
Year.The term of validity of foamaseptic can be speculated up to 2 years or more.
4.2. the accelerated test of the foamaseptic obtained by the present invention
Foamaseptic 9,10,11,12 4 prescriptions obtained by the present invention are taken, the artificial gas of SPX-250 micro computers is put into
Case is waited, 40 DEG C ± 2 DEG C of temperature, relative humidity 75% ± 5% are selected, is placed six months with this condition, in the 0th, 1,2,3,6
Moon sampling, investigates relevant item, and the testing result with 0 month compares, and test result is shown in Table 4.
4 accelerated test of table investigates result
Test result is shown, by 6 months accelerated tests, the character of prescription 9,10,11,12, pH value, quaternary ammonium salt content
Without significant change, to further prove that the foamaseptic of the present invention has stronger stability.
Embodiment 5：
Clinical test：Foamaseptic is with folk prescription disinfectant to the surface on-site disinfection test comparative example of natural bacteria
5.1. test method：
With reference to Ministry of Health of the People's Republic of China《Disinfection technology standard》(version in 2002) and the People's Republic of China (PRC) agricultural
Portion《Disinfectant for animals technical specification》(version in 1992) carry out disinfection experiment.
5.2. test drug：
Disinfectant is glutaraldehyde benzalkonium bromide solution, is provided by Luoyang Huizhong Veterinary Medicine Co. Ltd.；Foamaseptic：This hair
Bright obtained foamaseptic prescription 9.
5.3. test site and place election：
Luoyang is used as test site at great Qin industry Co., Ltd Ma Po at big chicken farm (equal 4 of every henhouse or more colony house)
Ground.
5.4. concrete operations
5.4.1. experiment grouping
(1) tested disinfectant group：Glutaraldehyde benzalkonium bromide solution+foam disinfectant auxiliary agent (V/V, 5:1)
(2) disinfectant group is compareed：Glutaraldehyde benzalkonium bromide solution
5.4.2. sampling sites
Feeding troughs of the Ma Po at henhouse in big chicken farm (equal 4 of every henhouse or more colony house), ground, each position adopts 3
A point.
5.4.3. concrete operations are tested
(1) it marks and sterilizes
4 colony houses are selected, 4 groups of A, B, C, D, each corresponding trial drug A, B, C, D group are respectively labeled as.Respectively in each circle
It gives up different sampling sites and respectively draws 3 regions, area is 5 × 5cm2Sampled point.It is respectively labeled as before sterilizing, after disinfection
60min after 40min, disinfection after 20min, disinfection.First disinfection forefoot area is sampled.Afterwards use corresponding decontaminant concentration into
Row disinfection, after disinfection 20min, 40min, 60min to A, B, C, D group echo be 40min after 20min, disinfection after disinfection,
The area sampling of 60min after disinfection.
(2) it samples
Sterile cotton swab is bedewed in the test tube of the sample solution containing 5ml, wherein the sample solution before disinfection is sterile physiological salt
Water, the sample solution after disinfection are sterile neutralizer.Sterile cotton swab after adhesional wetting squeezes on tube wall removes surplus liquid, in sampled point
Swabing sampling is carried out, respectively firmly wiping 10 times, rotate cotton swab in sampling, after sampling, swab cotton end is cut anyhow
Enter containing in former test tube, seals centrifuge tube, centrifuge tube is eluted bacterium with 2500 revs/min of mixing 30s in vortex vortex mixer, it is spare.
(3) count of bacteria
The sample washing lotion adopted before disinfection does 10 times of gradient dilutions with sterile saline, is diluted to 10-3Times.
Henhouse is sampled, bacterial counting is as follows：
To the sample 10 before disinfection-1、10-220min, 40min, 60min eluent stoste, 10 after dilution and disinfection-1It is dilute
It releases liquid and carries out count of bacteria.Every part is drawn 100 μ l sample liquids on Martin's agar plate containing 10% serum, and each sample is inoculated with
2 plates put 37 DEG C of constant incubator culture 12-14h, carry out count of bacteria.Simultaneously by used same batch neutralizer, dilution
Each 100 μ l inoculation mediums of liquid, as negative control group sample, and calculate sterilizing rate.
Jun Shuo ╳ 100% living before sterilizing rate %=(viable count after viable count-disinfection before disinfection)/disinfection
(4) test result
Foamaseptic the results are shown in Table henhouse crib and ground natural bacteria surface on-site disinfection test with folk prescription disinfectant
5, table 6.
According to the disinfectant in table 5 to henhouse crib on-the-spot disinfection result,
Glutaraldehyde benzalkonium bromide+foam disinfectant auxiliary combination solution can be realized and quickly and effectively be sterilized, dilute by 200 times
After releasing disinfection 20min, sterilizing rate is up to 98.27% or more, and different extension rates are to henhouse crib natural bacteria Disinfection Effect
It has no significant effect；Simple glutaraldehyde benzalkonium bromide solution is by 200 times of dilutions, after sterilizing 20min, sterilizing rate highest 94.26%,
With the increase of extension rate, bactericidal effect gradually lowers other multiple bactericidal effects, illustrates that the addition of foam disinfectant auxiliary agent makes to disappear
Chemical agent decontamination effect and efficiency are remarkably reinforced, and foam disinfectant auxiliary agent is still effective under the action of high dilution (1000 times),
Obtained foamaseptic has preferable stability
Disinfectant in table 6 can learn henhouse ground on-the-spot disinfection result and the comparison of table 5, glutaraldehyde benzalkonium bromide
+ foam disinfectant auxiliary combination solution is suitable with crib to the Disinfection Effect on henhouse ground, and simple glutaraldehyde benzalkonium bromide solution
Crib is better than to the Disinfection Effect on henhouse ground, illustrates that the addition of foam disinfectant auxiliary agent makes disinfectant to being in paliform, having dead angle
Extraordinary Disinfection Effect is played etc. complicated body surface.
5 disinfectant of table is to henhouse crib natural bacteria surface on-site disinfection test result
6 disinfectant of table is to henhouse ground natural bacteria surface on-site disinfection test result
Claims (10)
1. a kind of foam disinfectant auxiliary agent, which is characterized in that contain quaternary surfactant 40- in the foam disinfectant auxiliary agent
80% (W/V), tackifier 0.1-1.5% (W/V), stabilizer 0.5-2% (W/V).
2. foam disinfectant auxiliary agent according to claim 1, which is characterized in that its each component and each component content are：
Preferably, each component of the foam disinfectant auxiliary agent and each component content are：
It is highly preferred that the cleaning additive is four sodium of iminodisuccinic acid.
3. foam disinfectant auxiliary agent according to claim 1, which is characterized in that the quaternary surfactant is benzene
Prick bromine ammonium or benzalkonium chloride.
4. foam disinfectant auxiliary agent according to claim 1, which is characterized in that the tackifier are dimethyl
Base amine oxide or empgen BB.
5. foam disinfectant auxiliary agent according to claim 1, which is characterized in that the stabilizer is Arabic gum or sea
Mosanom.
6. foam disinfectant auxiliary agent according to claim 1, which is characterized in that its each component and each component content are：
7. a kind of preparation method according to claims 1-6 any one of them foam disinfectant auxiliary agents includes the following steps：
1) quaternary surfactant is weighed in the ratio of whole content 40%-80%W/V, suitable water, heating is added to make it dissolve；
2) stabilizer is weighed in the ratio of whole content 0.5-2%W/V, a small amount of water is added, be gradually heated to 80 DEG C, temperature is kept to stir
20min is mixed, until it is completely dissolved；And
3) will in step 2) the complete stabilizer of dissolving and whole content 0.1-1.5%W/V tackifier, essence, cleaning additive with
Liquid is mixed evenly in step 1), waits for liquid cooled to room temperature, adjusts pH value to about 7.0, add suitable quantity of water constant volume to get
The foam disinfectant auxiliary agent.
8. a kind of foamaseptic, which is characterized in that the foamaseptic includes according to described in claims any one of 1-6
Foam disinfectant auxiliary agent and disinfectant；
Preferably, it after the foamaseptic is diluted to 50~1000 times by the foam disinfectant auxiliary agent, is pressed with the disinfectant
1:1~1:10 ratio mixing composition；
It is highly preferred that after the foamaseptic is diluted to 50~1000 times by the foam disinfectant auxiliary agent, with the disinfectant
By 1:5 ratio mixing composition.
9. foamaseptic according to claim 8, it is characterized in that, the disinfectant be glutaraldehyde benzalkonium bromide, Iodophor,
At least one of povidone iodine, bleaching powder, sodium hypochlorite, chlorine dioxide, Peracetic acid and hydrogen peroxide.
10. a kind of foam disinfectant auxiliary agent according to claim 1, or foamaseptic according to claim 8,
Application, which is characterized in that the foam disinfectant auxiliary agent or the foamaseptic are applied to livestock and poultry cultivation place, poultry
Pouity dwelling place utensil, especially to having with rill, having mesh, in the disinfection of the complicated body surface such as paliform.
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