CN108524385A - A kind of astaxanthin multiple-effect Essence and preparation method thereof - Google Patents
A kind of astaxanthin multiple-effect Essence and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of astaxanthin multiple-effect Essences, including：Any or arbitrary several mixture of Sodium Hyaluronate, acrylic copolymer, card wave, glycine betaine, propylene glycol, butanediol, methyl hydroxybenzoate, methylisothiazolinone, glucan, niacinamide, ursin, algae extract, triethanolamine, astaxanthin, essence, water and Gotu Kola P.E, german chamomile flower extract, aloe barbadensis Miller leaf extract and glycoprotein, preparation method are：Water, Sodium Hyaluronate, acrylic copolymer, card wave, glycine betaine, propylene glycol, butanediol, methyl hydroxybenzoate, methylisothiazolinone are mixed in parts by weight fully dispersed, is stirred after heating, be then allowed to stand cooling；It is fully dispersed to get to the astaxanthin multiple-effect Essence that remaining material is added in parts by weight.The effect of astaxanthin multiple-effect Essence of the present invention has good penetrability, easily absorbs, anti-aging.
Description
Technical field
The present invention relates to cosmetic field, it is related to a kind of Essence and preparation method thereof more particularly to a kind of astaxanthin is more
Imitate Essence and preparation method thereof.
Background technology
Skin aging is the various factors comprehensive function such as a progressive physiology course, and heredity, environment, social mentality
Result.As the improvement of people's living standards, the functional requirement to skin care item is higher and higher, has the skin care of anti-aging effects
Product also emerge one after another；Essence is a kind of skin care item of the high nutrition ingredient added with concentration, according to the specific aim of its formula, tool
Have it is anti-ageing, crease-resistant, compact, moisturizing, Bearberry Extract, but a variety of concentration essence are added in product composition, while being also added to
More preservatives are especially easy the carcinogenic preservative of sensitization, such as dibutyl hydroxy toluene and benzyl alcohol, in addition, current
Therefore the problem of Essence is not easy to absorb also in the prevalence of poor permeability, single effect seeks safer, milder, more
Effective skin care item are very urgent.
Astaxanthin i.e. 3,3 '-dihydroxy -4,4 '-diketo-β, β '-carrotene are terpenes unsaturated compounds.Shrimp
Green element is widely present in nature, and as in most of shellfish and salmon fishes body, the leaf of plant, flower, fruit, and fire are strong
The feather of bird is medium.Astaxanthin has a variety of physiological functions, such as inoxidizability, antitumor, pre- anti-cancer, strengthen immunity,
Improving eyesight etc. has certain effect, using the antioxygenic property that astaxanthin is excellent, can effectively improve Essence and prolong
The effect of slow aging, but have no any Essence using astaxanthin as active ingredient at present.
Invention content
In view of this, the present invention provides a kind of astaxanthin multiple-effect Essence and preparation method thereof, with prepare good penetrability,
Easily absorb, the skin that can releive, anti-aging astaxanthin-containing Essence.
To achieve the goals above, the present invention adopts the following technical scheme that：
A kind of astaxanthin multiple-effect Essence, includes the raw material of following parts by weight：
0.05-0.15 parts of Sodium Hyaluronate, 0.10-0.20 parts of acrylic copolymer, 0.1-0.2 parts of card wave, glycine betaine
1-3 parts, 2-5 parts of propylene glycol, 3-4 parts of butanediol, 0.1-0.2 parts of methyl hydroxybenzoate, 0.3-0.5 parts of methylisothiazolinone, Portugal it is poly-
2-5 parts sugared, 2-5 parts of niacinamide, 0.2-0.4 parts of ursin, 1-3 parts of algae extract, 0.2-0.4 parts of triethanolamine, astaxanthin
0.01-0.03 parts, 0.0005-0.001 parts of essence, 78-85 parts of water and Gotu Kola P.E, german chamomile flower extract, Curacao reed
Any or arbitrary 1-4 parts several of mixture of luxuriant growth leaf extract and glycoprotein；
Preferably, the parts by weight of above-mentioned raw materials are：
0.1 part of Sodium Hyaluronate, 0.15 part of acrylic copolymer, 0.2 part of card wave, 1 part of glycine betaine, 4 parts of propylene glycol, fourth
4 parts of glycol, 0.1 part of methyl hydroxybenzoate, 0.3 part of methylisothiazolinone, 2 parts of glucan, 2 parts of niacinamide, 0.4 part of ursin, algae
2 parts of extract, 0.2 part of triethanolamine, 0.01 part of astaxanthin, 0.0008 part of essence, 81.6 parts of water and Gotu Kola P.E, german chamomile
Any or arbitrary 2 parts several of mixture of flower extract, aloe barbadensis Miller leaf extract and glycoprotein.
The beneficial effects of the invention are as follows：The astaxanthin multiple-effect Essence of the present invention is with the main aging ingredient of astaxanthin, and one
Aspect locks moisture of skin, increases skin elasticity, and on the other hand there are many bio-extracts for addition in the present invention, penetrate into skin
Skin grown layer weakens the oxidation reaction of photon, can start the phosphorylated tyrosine kinase of specificity under the assistance of Tocopherol,
The oxidative damage of DNA is prevented, the expression of ultraviolet light human skin's fibroblast Collagenase is inhibited, protects skin
From damage, delaying skin aging, and suitable propylene glycol and butanediol are reasonably added, contributes to the work in Essence
Property ingredient penetrates into skin.Therefore, astaxanthin multiple-effect Essence of the invention not only has preferable moisturizing, moisturizing effect, strong
Big anti-aging ability, which also can be that skin is anti-ageing, provides endlessly power.
The preparation method of above-mentioned astaxanthin multiple-effect Essence includes the following steps：
Step 1) is by water, Sodium Hyaluronate, acrylic copolymer, card wave, glycine betaine, propylene glycol, butanediol, oxybenzene first
Ester, methylisothiazolinone mix in parts by weight, with 600-800rpm, the preferably fully dispersed 5- of the rotating speed of 600rpm
15min, preferably 5min are heated to 80-85 DEG C, stir 20-50min, preferably 30min after preferably 85 DEG C, be then allowed to stand drop
Temperature is to 30-45 DEG C, preferably 40 DEG C；
Glucan, niacinamide, ursin, algae extract, triethanolamine, astaxanthin, perfume (or spice) is added in step 2) in parts by weight
Essence and Gotu Kola P.E, german chamomile flower extract, aloe barbadensis Miller leaf extract and glycoprotein it is any or arbitrary several
Mixture, with 600-800rpm, the preferably fully dispersed 1-10min of the rotating speed of 600rpm, preferably 1min is to get green to the shrimp
Plain multiple-effect Essence.
The advantageous effect of preparation method of the present invention is：So that each raw material component in the present invention in astaxanthin multiple-effect Essence
It is fully dispersed and relatively high bioactivity can be kept.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below.
Embodiment 1
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 81.6g, Sodium Hyaluronate 0.1g, acrylic copolymer 0.15g, card wave 0.2g, glycine betaine 1g,
Propylene glycol 4g, butanediol 4g, methyl hydroxybenzoate 0.1g, methylisothiazolinone 0.3g mixing are fully dispersed with 600 rotating speed
5min stirs 30min after being heated to 85 DEG C, is then allowed to stand and is cooled to 40 DEG C；
Step 2) is added Gotu Kola P.E 2g and glucan 2g, niacinamide 2g, ursin 0.4g, algae extract 2g, and three
Ethanol amine 0.2g, astaxanthin 0.01g, essence 0.0008g, with the fully dispersed 1min of the rotating speed of 600rpm to get more to astaxanthin
Imitate Essence.
Embodiment 2
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 78g, Sodium Hyaluronate 0.05g, acrylic copolymer 0.10g, card wave 0.1g, glycine betaine 1g,
Propylene glycol 2g, butanediol 3g, methyl hydroxybenzoate 0.1g, methylisothiazolinone 0.3g mixing are fully dispersed with the rotating speed of 600rpm
5min is heated to 80 DEG C, stirs 20min afterwards, is then allowed to stand and is cooled to 30 DEG C；
Step 2) is added Gotu Kola P.E 1g and glucan 2g, niacinamide 2g, ursin 0.2g, algae extract 1g, and three
Ethanol amine 0.2g, astaxanthin 0.01g, essence 0.0005g, with the fully dispersed 1min of the rotating speed of 600rpm to get more to astaxanthin
Imitate Essence.
Embodiment 3
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 85g, Sodium Hyaluronate 0.15g, acrylic copolymer 0.20g, card wave 0.2g, glycine betaine 3g,
Propylene glycol 5g, butanediol 4g, methyl hydroxybenzoate 0.2g, methylisothiazolinone 0.5g mixing are fully dispersed with the rotating speed of 800rpm
15min is heated to 85 DEG C, stirs 50min afterwards, is then allowed to stand and is cooled to 45 DEG C；
Step 2) is added german chamomile flower extract 4g and glucan 5g, niacinamide 5g, ursin 0.4g, algae extract 3g, and three
Ethanol amine 0.4g, astaxanthin 0.03g, essence 0.001g, with the fully dispersed 10min of the rotating speed of 800rpm to get more to astaxanthin
Imitate Essence.
Embodiment 4
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 80g, Sodium Hyaluronate 0.1g, acrylic copolymer 0.15g, card wave 0.1g, glycine betaine 3g, and third
Glycol 5g, butanediol 3g, methyl hydroxybenzoate 0.2g, methylisothiazolinone 0.4g mixing are fully dispersed with the rotating speed of 700rpm
10min stirs 30min after being heated to 80 DEG C, is then allowed to stand and is cooled to 32 DEG C；
Aloe barbadensis Miller leaf extract 3g and glucan 3g, niacinamide 5g, ursin 0.3g, algae extract is added in step 2)
1g, triethanolamine 0.2g, astaxanthin 0.02g, essence 0.0008g, with the fully dispersed 5min of the rotating speed of 750rpm to get green to shrimp
Plain multiple-effect Essence.
Embodiment 5
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 82g, Sodium Hyaluronate 0.1g, acrylic copolymer 0.15g, card wave 0.15g, glycine betaine 2g,
Propylene glycol 4g, butanediol 4g, methyl hydroxybenzoate 0.1g, methylisothiazolinone 0.4g mixing are fully dispersed with the rotating speed of 750rpm
12min stirs 45min after being heated to 82 DEG C, is then allowed to stand and is cooled to 32 DEG C；
Any 3g and glucan 5g of step 2) addition glycoprotein, niacinamide 2g, ursin 0.3g, algae extract 2g,
Triethanolamine 0.3g, astaxanthin 0.02g, essence 0.0009g, with the fully dispersed 8min of the rotating speed of 750rpm to get to astaxanthin
Multiple-effect Essence.
Embodiment 6
The preparation method of astaxanthin multiple-effect Essence of the present invention includes：
Step 1) is by water 82g, Sodium Hyaluronate 0.12g, acrylic copolymer 0.18g, card wave 0.15g, glycine betaine 2g,
Propylene glycol 2g, butanediol 4g, methyl hydroxybenzoate 0.1g, methylisothiazolinone 0.5g mixing are fully dispersed with the rotating speed of 650rpm
12min is heated to 80 DEG C, stirs 48min afterwards, is then allowed to stand and is cooled to 32 DEG C；
Glucan 2g, niacinamide 3g, ursin 0.3g, algae extract 3g, triethanolamine 0.2g, astaxanthin is added in step 2)
0.03g, essence 0.0008g and Gotu Kola P.E, german chamomile flower extract, aloe barbadensis Miller leaf extract and glycoprotein are with 1：
1：1：1 quality is than blend mixture 3g, with the fully dispersed 5min of the rotating speed of 700rpm to get to astaxanthin multiple-effect Essence.
Performance detection
One, security test
It chooses to cosmetics without allergy, facial no acute inflammation, hormone medicine or immunosuppressor be not used, participate in
External preparation healthy volunteer 60 is not smeared in other clinical tests, by the astaxanthin multiple-effect prepared by 1-6 of the embodiment of the present invention
Essence carries out human skin patch and evaluates its safety.
As a result it shows：Each group subject is small 0.5,6,12,24,48 by the patch tests of embodiment 1-6 test samples
When observe dermoreaction, wherein 0 skin adverse reaction occurs, illustrate that composition prepared by 1-6 of the embodiment of the present invention is safety
Non-stimulated.
Two, efficacy test
1) crowd is tested：The healthy volunteer 70 for choosing dry skin, thering are the wrinkles such as dry line, microgroove, expression line to perplex,
It is age 38-50 Sui, 43 years old average, to cosmetics without allergy, facial no acute inflammation, unused hormone medicine or immunosupress
Other clinical tests are not participated in agent, do not smear external preparation.7 groups are randomly divided into, every group of 10 people use the present invention respectively successively
Astaxanthin multiple-effect Essence prepared by embodiment 1-6, and as a control group with certain commercially available brand Essence.
2) test method：After each group volunteer warm water cleaning skin, corresponding test sample is uniformly smeared in face, often
It each 1 time sooner or later, after being used continuously 8 weeks, moisture of skin measuring instrument Corneometer CM825 is used to measure facial skin keratin
Water content in layer, and calculated hydration rate (%)；Facial forehead skin is measured using skin oil and fat content measuring instrument Sebumeter
Fat content；Testing facial skin elasticity using skin elasticity tester MPA580, (negative pressure is constant in test process is
450mpa), ratios of the springback capacity Ur (recovery value for cancelling negative pressure skin after 0.1 second) with the maximum tension amount Uf of skin is as a result used
Value indicates that numerical value illustrates that skin elasticity is better closer to 1；The above experimental results such as table 1.
1 each test sample test result of table
The above results show that lotion prepared by composition of the embodiment of the present invention has good replenishing water and preserving moisture effect, and
The secretion of grease can be effectively reduced, increases elasticity of skin, has the function that moisturizing, oil-control and anti-aging.
Three, normal individual trial is evaluated
1) test population：210,20-50 Sui, oiliness, skin are intense darkness without light subject that is damp and being sensitive skin, gender
At random, it is divided into 7 groups, every group of 30 people, every group of average age 38 ± 2 years old.
2) test sample：
Astaxanthin multiple-effect Essence prepared by 1-6 of the embodiment of the present invention, and as a contrast with certain commercially available brand Essence
Group.
3) test method：After subject cleans face, test sample is applied to face, uses 2 times weekly, continuously makes at night
With 4 weeks.Degree and elastic, oil-control effect mainly are moistened to moisturizing moisturizing, skin and effect of releiving is evaluated, evaluation result is such as
Under：
(1) moisturizing moisturizing effect：Through statistics, in the volunteer of astaxanthin multiple-effect Essence in embodiment 1-6 85% is used
Indicate the skin moisture-keeping time at 10 hours or so；The skin moisture-keeping time is indicated using in the volunteer of comparative example Essence 73% not
Foot 8 hours.
(2) skin moistens degree and elasticity：Through statistics, using in the volunteer of astaxanthin multiple-effect Essence in embodiment 1-6
93% indicates obviously to moisturize the skin, and increases skin elasticity, and skin becomes fine and smooth；In volunteer using comparative example Essence
65% indicates that dry skin can be improved, and 45% indicates to feel not enough to moisten, without feeling to increase skin after 52% expression use
Elasticity, skin do not become fine and smooth.
(3) oil-control effect：Through statistics, indicated using in the volunteer of astaxanthin multiple-effect Essence in embodiment 1-6 83%
The water content of skin can be significantly improved, fat secretion significantly reduces；Being indicated using in the volunteer of comparative example Essence 65% can
Increased with skin water content, 45% expression skin still there are glossy, oil-control effect unobvious.
(4) it releives effect：Through statistics, Essence in astaxanthin multiple-effect Essence in embodiment 1-6 and comparative example is used
Volunteer does not occur any allergy discomfort phenomenon, wherein in the volunteer using astaxanthin multiple-effect Essence in embodiment 1-6
The red blood silk of 80% expression face, which has, obviously to shoal；The red blood for indicating face using in the volunteer of Essence in comparative example 50%
Silk only slightly shoals, and the red blood silk of 50% expression face is simultaneously not improved.
Above-described embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
Claims (8)
1. a kind of astaxanthin multiple-effect Essence, which is characterized in that include the raw material of following parts by weight：
0.05-0.15 parts of Sodium Hyaluronate, 0.10-0.20 parts of acrylic copolymer, 0.1-0.2 parts of card wave, glycine betaine 1-3
Part, 2-5 parts of propylene glycol, 3-4 parts of butanediol, 0.1-0.2 parts of methyl hydroxybenzoate, 0.3-0.5 parts of methylisothiazolinone, glucan 2-
5 parts, 2-5 parts of niacinamide, 0.2-0.4 parts of ursin, 1-3 parts of algae extract, 0.2-0.4 parts of triethanolamine, astaxanthin 0.01-
0.03 part, 0.0005-0.001 parts of essence, 78-85 parts of water and Gotu Kola P.E, german chamomile flower extract, Aloe Barbadensis Miller carry
Take any or arbitrary 1-4 parts several of mixture of object and glycoprotein.
2. a kind of astaxanthin multiple-effect Essence according to claim 1, which is characterized in that include the original of following parts by weight
Material：
0.1 part of Sodium Hyaluronate, 0.15 part of acrylic copolymer, 0.2 part of card wave, 1 part of glycine betaine, 4 parts of propylene glycol, butanediol
4 parts, 0.1 part of methyl hydroxybenzoate, 0.3 part of methylisothiazolinone, 2 parts of glucan, 2 parts of niacinamide, 0.4 part of ursin, algae extraction
2 parts of object, 0.2 part of triethanolamine, 0.01 part of astaxanthin, 0.0008 part of essence, 81.6 parts of water and Gotu Kola P.E, Flos Chrysanthemi carry
Take any of object, aloe barbadensis Miller leaf extract and glycoprotein or arbitrary 2 parts several of mixture.
3. according to a kind of astaxanthin multiple-effect Essence of claim 1-2 any one of them, which is characterized in that the astaxanthin is more
The preparation method of effect Essence includes the following steps：
Step 1) by water, Sodium Hyaluronate, acrylic copolymer, card wave, glycine betaine, propylene glycol, butanediol, methyl hydroxybenzoate,
Methylisothiazolinone mixes fully dispersed in parts by weight, is stirred after heating, is then allowed to stand cooling；
Step 2) be added in parts by weight glucan, niacinamide, ursin, algae extract, triethanolamine, astaxanthin, essence and
Any or arbitrary several mixing of Gotu Kola P.E, german chamomile flower extract, aloe barbadensis Miller leaf extract and glycoprotein
Object is fully dispersed to get to the astaxanthin multiple-effect Essence.
4. a kind of astaxanthin multiple-effect Essence according to claim 3, which is characterized in that disperses described in step 1) turns
Speed is 600-800rpm, jitter time 5-15min.
5. a kind of astaxanthin multiple-effect Essence according to claim 3, which is characterized in that be heated to be described in step 1) and add
Heat is to 80-85 DEG C.
6. a kind of astaxanthin multiple-effect Essence according to claim 3, which is characterized in that mixing time described in step 1)
For 20-50min.
7. a kind of astaxanthin multiple-effect Essence according to claim 3, which is characterized in that cooling described in step 1) is drop
Temperature is to 30-45 DEG C.
8. a kind of astaxanthin multiple-effect Essence according to claim 3, which is characterized in that disperses described in step 2) turns
Speed is 600-800rpm, jitter time 1-10min.
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| CN109998967A (en) * | 2019-01-21 | 2019-07-12 | 秋臣化妆品有限公司 | A kind of small pox disappears Essence and preparation method thereof |
| CN110731912A (en) * | 2019-11-20 | 2020-01-31 | 广州瑞誉化工科技有限公司 | whitening and anti-aging essence |
| CN111920750A (en) * | 2020-09-01 | 2020-11-13 | 广州市鑫晞莱生物科技有限公司 | Preparation method of skin care essence stock solution |
| CN113143808A (en) * | 2021-03-02 | 2021-07-23 | 珠海市何伟有机食品有限公司 | Firming and repairing essence containing Adiantum henryi seed flower extract and preparation method thereof |
| CN113303474A (en) * | 2021-06-09 | 2021-08-27 | 云南爱尔发生物技术股份有限公司 | A nutritional food containing astaxanthin hyaluronic acid |
| CN113648231A (en) * | 2021-09-30 | 2021-11-16 | 广东美思康宸药业股份有限公司 | Astaxanthin facial brightening and moisturizing mask liquid and preparation method thereof |
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Application publication date: 20180914 |