CN113648231B - Astaxanthin facial mask liquid capable of brightening and moisturizing and preparation method thereof - Google Patents

Astaxanthin facial mask liquid capable of brightening and moisturizing and preparation method thereof Download PDF

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CN113648231B
CN113648231B CN202111166475.4A CN202111166475A CN113648231B CN 113648231 B CN113648231 B CN 113648231B CN 202111166475 A CN202111166475 A CN 202111166475A CN 113648231 B CN113648231 B CN 113648231B
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astaxanthin
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CN113648231A (en
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詹乐武
黄建谋
蒋连金
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Guangdong Meisi Kangchen Pharmaceutical Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

An astaxanthin skin-brightening and moisturizing mask liquid, A group preparation comprises water, dipropylene glycol, betaine, polyacrylate crosslinked polymer-6, disodium ethylenediamine tetraacetate and allantoin; the preparation of the group B comprises 1, 3-propylene glycol, hydrolyzed sodium hyaluronate, sodium hyaluronate and xanthan gum; group C formulations include 1, 3-propanediol, methylparaben; group D formulations include 1, 3-propanediol and panthenol; group E formulations include 1, 2-pentanediol, PEG-40 hydrogenated castor oil, perfume, tocopheryl acetate; group F formulations include 1, 3-propanediol, astaxanthin; the group G preparation comprises sodium pyrrolidone carboxylate, wild soybean seed extract, wheat seed extract, water, chamomile extract and phenoxyethanol, the mask liquid solves the problem of application limitation of astaxanthin in the mask liquid in the prior art, and meanwhile, the astaxanthin skin-whitening and moisturizing mask liquid provided by the invention also has good moisturizing and skin-whitening effects.

Description

Astaxanthin facial mask liquid capable of brightening and moisturizing and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics and preparation thereof, and particularly relates to astaxanthin skin-brightening and moisturizing mask liquid and a preparation method thereof.
Background
The facial mask is a common skin care product in daily life, and utilizes short time covered on the face to promote pore expansion of the skin, promote sweat gland secretion and metabolism, increase oxygen content of the skin, promote the skin to remove products of surface cell metabolism and accumulated grease substances, and enable high-concentration nutrient components in the facial mask essence to enter the skin rapidly, so that the skin is quickly and effectively nursed.
Astaxanthin is a chain-breaking antioxidant. Has extremely strong antioxidant capacity, can remove nitrogen dioxide, sulfide, disulfide and the like, can reduce lipid peroxidation, and effectively inhibits lipid peroxidation caused by free radicals, but the application of the lipid peroxidation inhibitor in mask liquid can not well exert the efficacy.
Along with the continuous improvement of the living standard of people, the beauty concept is also greatly changed, and the safety and the high efficiency are paid more attention to while the beauty is pursued, but in practice, most of the existing mask liquid has poor whitening and repairing effects on the skin, meanwhile, the requirements of people on natural and healthy skin care products cannot be effectively met, and some similar products on the market have comprehensive effects, but are irritative, not mild enough and even contain substances violating the legal regulations of cosmetics, so that the mask liquid is unfavorable for the health of human skin and even human body.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the astaxanthin moisturizing facial mask liquid and the preparation method thereof, which solve the problem of application limitation of astaxanthin in the facial mask liquid in the prior art, and simultaneously the astaxanthin moisturizing facial mask liquid provided by the invention also has good moisturizing and skin color brightening effects. The invention comprises the following specific contents:
the invention aims to provide astaxanthin brightening moisturizing mask liquid, which has the technical points that: a formulation comprising group A, B, C, D, E, F, G;
the components of the A group preparation comprise water, dipropylene glycol, betaine, polyacrylate crosslinked polymer-6, disodium ethylenediamine tetraacetate and allantoin;
the components of the preparation in the group B comprise 1, 3-propylene glycol, hydrolyzed sodium hyaluronate, sodium hyaluronate and xanthan gum;
the components of the preparation in the group C comprise 1, 3-propylene glycol and methylparaben;
the components of the group D preparation comprise 1, 3-propanediol and panthenol;
the component of the E group preparation comprises 1, 2-pentanediol, PEG-40 hydrogenated castor oil, essence and tocopheryl acetate;
the components of the F group preparation comprise 1, 3-propylene glycol and astaxanthin;
the component of the G group preparation comprises sodium pyrrolidone carboxylate, wild soybean seed extract, wheat seed extract, water, chamomile extract and phenoxyethanol.
In some embodiments of the present invention, the astaxanthin skin-lightening and moisturizing mask liquid of the present invention comprises, by weight, 80-82 parts of water, 1-3 parts of dipropylene glycol, 1-3 parts of betaine, 0.2-0.4 part of polyacrylate crosslinked polymer-6, 0.02-0.04 part of disodium edetate, and 0.1-0.3 part of allantoin.
In some embodiments of the present invention, the astaxanthin skin-brightening and moisturizing mask liquid of the present invention comprises, by weight, 1-3 parts of 1, 3-propanediol, 0.04-0.06 parts of hydrolyzed sodium hyaluronate, 0.04-0.08 parts of sodium hyaluronate, and 0.14-0.16 parts of xanthan gum.
In some embodiments of the present invention, the astaxanthin skin-brightening and moisturizing mask liquid of the present invention comprises, by weight, 0.8-1.2 parts of 1, 3-propanediol and 0.08-0.12 parts of methylparaben.
In some embodiments of the invention, the astaxanthin skin-brightening and moisturizing mask liquid comprises 1.5-2.5 parts by weight of 1, 3-propanediol and 0.4-0.6 part by weight of panthenol.
In some embodiments of the present invention, the astaxanthin skin-brightening and moisturizing mask liquid of the present invention comprises, by weight, 1-3 parts of 1, 2-pentanediol, 0.06-0.10 parts of PEG-40 hydrogenated castor oil, 0.004-0.006 parts of essence, and 0.08-0.12 parts of tocopheryl acetate.
In some embodiments of the invention, the astaxanthin skin-brightening and moisturizing mask liquid comprises 1-3 parts by weight of 1, 3-propanediol and 0.01-0.03 part by weight of astaxanthin.
In some embodiments of the present invention, the astaxanthin skin-lightening and moisturizing mask liquid of the present invention comprises, by weight, 1-3 parts of sodium pyrrolidone carboxylate, 0.4-0.6 parts of wild soybean seed extract, 0.1-0.3 parts of wheat seed extract, 0.5-0.6 parts of water, 0.4-0.6 parts of chamomile flower extract, and 0.1-0.3 parts of phenoxyethanol.
The second aim of the invention is to provide a preparation method of astaxanthin skin-brightening and moisturizing mask liquid, which has the technical points that: the method comprises the following steps:
step one, cleaning and sterilizing all the production tools and pot groups for standby, and dispersing and dissolving the A group preparation and the G group preparation respectively for standby;
step two, adding the preparation of the group A into an emulsifying pot, stirring and heating to 80-90 ℃ to dissolve uniformly;
step three, uniformly stirring and dispersing the preparation of the group B, adding the preparation into an emulsifying pot, and stirring and cooling to 40-50 ℃;
step four, stirring and dissolving the preparation of the group C and the preparation of the group D respectively, and uniformly adding the mixture into an emulsifying pot;
step five, adding the preparation of the group E into an emulsifying pot and uniformly stirring;
step six, adding the preparation of the group F into an emulsifying pot and uniformly stirring;
and seventhly, sequentially adding the raw materials of the group G preparation into an emulsifying pot, uniformly stirring, taking a semi-finished product for detection, discharging to a standing room after the semi-finished product is qualified, filling and packaging.
Compared with the prior art, the astaxanthin skin-brightening and moisturizing mask liquid and the preparation method thereof have the beneficial effects that:
the astaxanthin skin-brightening and moisturizing mask liquid comprises A, B, C, D, E, F, G group of preparations, wherein the group A of preparations comprises water, dipropylene glycol, betaine, polyacrylate crosslinked polymer-6, disodium ethylenediamine tetraacetate and allantoin; the component of the preparation B comprises 1, 3-propylene glycol, hydrolyzed sodium hyaluronate, sodium hyaluronate and xanthan gum; the component of the preparation of the group C comprises 1, 3-propylene glycol and methylparaben; the component of the group D preparation comprises 1, 3-propylene glycol and panthenol; the component of the E group preparation comprises 1, 2-pentanediol, PEG-40 hydrogenated castor oil, essence and tocopheryl acetate; the component of the F group preparation comprises 1, 3-propylene glycol and astaxanthin; the composition of the G group preparation comprises sodium pyrrolidone carboxylate, wild soybean seed extract, wheat seed extract, water, chamomile extract and phenoxyethanol, the mask liquid solves the problem of application limitation of astaxanthin in the mask liquid in the prior art, and meanwhile, the astaxanthin skin-whitening and moisturizing mask liquid provided by the invention also has good effects of moisturizing and brightening skin colors.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to examples, but it will be understood by those skilled in the art that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer.
Example 1
The mask liquid of the examples was prepared according to the following formulation:
table 1 astaxanthin skin-brightening moisturizing mask liquid formula
Figure BDA0003291510960000051
/>
Figure BDA0003291510960000061
/>
Figure BDA0003291510960000071
Example 2
The mask liquid of the examples was prepared according to the following formulation:
table 2 astaxanthin skin-brightening moisturizing mask liquid formula
Figure BDA0003291510960000072
/>
Figure BDA0003291510960000081
Example 3
The mask liquid of the examples was prepared according to the following formulation:
table 3 astaxanthin skin-brightening moisturizing mask liquid formula
Figure BDA0003291510960000082
/>
Figure BDA0003291510960000091
Test examples
Selecting 60 patients with dark yellow face skin color, dry skin and obvious molting for test, dividing the patients into 3 groups, 20 positions each group, soaking mask paper in the astaxanthin skin-brightening and moisturizing mask liquid prepared in the examples 1-3 for 2min, spreading the mask paper on the face, sticking the mask paper for about 10min each time, cleaning the mask paper with clear water, using the mask paper once every day for 3 days, counting the number of patients healed, effective, improved and ineffective after 30 days, and calculating the total effective rate (%); curative effect judgment criteria: (1) and (3) healing: skin color improvement (white and transparent), complete elimination of molt, smooth and moist skin with elasticity; (2) the effect is shown: the skin color is improved to a great extent (fair and transparent), and the molt is obviously resolved; (3) improvement: skin color is improved (fair and transparent) and molt is resolved; (4) invalidation: skin tone, molt change was not apparent or aggravated, and the experimental results are shown in table 4:
TABLE 4 Table 4
Figure BDA0003291510960000101
While particular embodiments of the present invention have been illustrated and described, it will be appreciated that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

Claims (2)

1. An astaxanthin skin brightening moisturizing mask liquid is characterized in that: is composed of A, B, C, D, E, F, G group preparations;
the A group preparation consists of 80-82 parts by weight of water, 1-3 parts by weight of dipropylene glycol, 1-3 parts by weight of betaine, 0.2-0.4 part by weight of polyacrylate crosslinked polymer-6, 0.02-0.04 part by weight of disodium ethylenediamine tetraacetate and 0.1-0.3 part by weight of allantoin;
the preparation in group B consists of 1-3 parts by weight of 1, 3-propylene glycol, 0.04-0.06 part by weight of hydrolyzed sodium hyaluronate, 0.04-0.08 part by weight of sodium hyaluronate and 0.14-0.16 part by weight of xanthan gum;
the preparation of the group C consists of 0.8-1.2 parts by weight of 1, 3-propanediol and 0.08-0.12 part by weight of methylparaben;
the group D preparation consists of 1.5-2.5 parts by weight of 1, 3-propanediol and 0.4-0.6 part by weight of panthenol;
the E group preparation consists of 1-3 parts by weight of 1, 2-pentanediol, 0.06-0.10 part by weight of PEG-40 hydrogenated castor oil, 0.004-0.006 part by weight of essence and 0.08-0.12 part by weight of tocopheryl acetate;
the F group preparation consists of 1-3 parts by weight of 1, 3-propanediol and 0.01-0.03 part by weight of astaxanthin according to parts by weight;
the group G preparation consists of 1-3 parts by weight of sodium pyrrolidone carboxylate, 0.4-0.6 part by weight of wild soybean seed extract, 0.1-0.3 part by weight of wheat seed extract, 0.5-0.6 part by weight of water, 0.4-0.6 part by weight of mother chrysanthemum extract and 0.1-0.3 part by weight of phenoxyethanol.
2. The method for preparing the astaxanthin skin-brightening moisturizing mask liquid according to claim 1, which is characterized in that: the method comprises the following steps:
step one, cleaning and sterilizing all the production tools and pot groups for standby, and dispersing and dissolving the A group preparation and the G group preparation respectively for standby;
step two, adding the preparation of the group A into an emulsifying pot, stirring and heating to 80-90 ℃ to dissolve uniformly;
step three, uniformly stirring and dispersing the preparation of the group B, adding the preparation into an emulsifying pot, and stirring and cooling to 40-50 ℃;
step four, stirring and dissolving the preparation of the group C and the preparation of the group D respectively, and uniformly adding the mixture into an emulsifying pot;
step five, adding the preparation of the group E into an emulsifying pot and uniformly stirring;
step six, adding the preparation of the group F into an emulsifying pot and uniformly stirring;
and seventhly, sequentially adding the raw materials of the group G preparation into an emulsifying pot, uniformly stirring, taking a semi-finished product for detection, discharging to a standing room after the semi-finished product is qualified, filling and packaging.
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Citations (1)

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Publication number Priority date Publication date Assignee Title
CN108524385A (en) * 2018-03-27 2018-09-14 赵金椿 A kind of astaxanthin multiple-effect Essence and preparation method thereof

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CN112386511A (en) * 2019-08-14 2021-02-23 李和伟 Carrier-free facial mask and preparation method and application thereof
CN110448472A (en) * 2019-09-25 2019-11-15 珠海伊斯佳科技股份有限公司 A kind of facial mask liquid and preparation method thereof that water oil two-phase mixes immediately
JP7269855B2 (en) * 2019-09-30 2023-05-09 久光製薬株式会社 gel sheet mask

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