CN108513574B - N-磺酰化吡唑并[3，4-b]吡啶-6-甲酰胺和使用方法 - Google Patents

N-磺酰化吡唑并[3，4-b]吡啶-6-甲酰胺和使用方法 Download PDF

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CN108513574B
CN108513574B CN201680069459.4A CN201680069459A CN108513574B CN 108513574 B CN108513574 B CN 108513574B CN 201680069459 A CN201680069459 A CN 201680069459A CN 108513574 B CN108513574 B CN 108513574B
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pyridine
carboxamide
pyrazolo
phenyl
cyclobutyl
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CN201680069459.4A
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Chinese (zh)
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CN108513574A (zh
Inventor
R.阿卡里
L.J.阿尔维
X.M.波克
B.S.布朗
P.I.R.克莱斯
M.D.科瓦特
E.德勒莫斯
N.德斯罗伊
B.杜蒂安
G.A.格菲泽尔
R.L.M.戈斯米尼
C.G.霍斯曼
K.K.詹森
纪建国
P.R.凯姆
J-M.勒弗朗索瓦
O.马莫利蒂
C.J.M.梅内特
N.M.梅拉尤
G.J.R.纽索姆
A.M.E.帕利斯
S.V.帕特尔
M.R.皮佐内罗
A.什雷斯塔
E.C.斯威夫特
S.E.范德普拉斯
王学庆
A.德布利克
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Galapagos NV
AbbVie Inc
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Galapagos NV
AbbVie Inc
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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CN201680069459.4A 2015-10-09 2016-10-07 N-磺酰化吡唑并[3，4-b]吡啶-6-甲酰胺和使用方法 Active CN108513574B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562239647P 2015-10-09 2015-10-09
US62/239647 2015-10-09
US201662309794P 2016-03-17 2016-03-17
US62/309794 2016-03-17
PCT/IB2016/056029 WO2017060874A1 (en) 2015-10-09 2016-10-07 N-sulfonylated pyrazolo[3,4-b]pyridin-6-carboxamides and method of use

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CN108513574A CN108513574A (zh) 2018-09-07
CN108513574B true CN108513574B (zh) 2021-01-05

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