CN108451892A - A kind of Essence and preparation method thereof with long-acting moisture-keeping efficacy - Google Patents
A kind of Essence and preparation method thereof with long-acting moisture-keeping efficacy Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The invention discloses a kind of Essences and preparation method thereof with long-acting moisture-keeping efficacy.By mass percentage, the Essence is grouped as by the following raw material group:Long-acting moisturizing complexing agent 5 15%, solvent 80 90%, thickener 0.1 1%, pH adjusting agent 0.1 1%, skin conditioning agent 0.5 1%, preservative 0.2 1%, aromatic 0.05 0.5%.The long-acting moisturizing complexing agent includes:10 25% Mel extract, 20 40% Acer negundo extract, 15 30% saccharomycete/rice fermentation Product filtrate, 0.5 5% arginine HCl, 0.5 5% lysine HCl, 0.5 5% ornithine HCl, 0.5 5% Cer NP, 0.5 5% Cer AP II, 0.5 5% Cer EOS, 10 20% lauroyl dilactic acid sodium, 0.5 5% phytosphingosine, 0.5 5% cholesterine.The Essence of the present invention has the moistening effect up to 4 8h by optimizing the compounding and adding proportion of long-acting moisturizing complexing agent.
Description
Technical field
The present invention relates to a kind of moisturizing essence, belong to cosmetic technical field, and in particular to one kind having long-acting moisturizing
Essence of effect and preparation method thereof.
Background technology
Moisturizing, be carry out skin nursing most it is basic be also most important link.Whether the moisture of skin is full, not only directly
The external complexion of a people is influenced, or even a series of skin healths such as chapped skin, corrugation, husking, allergy can also be caused to be asked
Topic.Important category one of of the Essence as cosmetics, largely both having met the psychology of the high-end consumption of consumer needs
It asks, while being also the effective way that consumer carries out skin moisture-keeping supplement skin-nourishing.
The Essence of current moisturizing class on the market, common moisturizing ingredient is mostly water soluble humectants.Glycerine, butanediol etc.
Polyalcohol is easy to be absorbed by the skin because molecular weight is small, is usually used in basic moisturizing, but does not have the effect of long-acting moisturizing.Sea
The macromolecules moisturizer such as algae sugar, glucan, Sodium Hyaluronate, moistening effect is good, but the partially glutinous thickness of skin sense, use cost are also opposite
It is higher.And as oil moistures' ingredient such as vaseline, saualane, it is insoluble in water, is mostly used in lotion or cream dosage form.
Therefore, various to adapt to market there is an urgent need to a skin-protection product appearance for capableing of long-acting moisturizing skin
Selection demand.
Invention content
The purpose of the present invention is to provide a kind of Essences with long-acting moisture-keeping efficacy, wherein the long-acting moisturizing added is multiple
Mixture has organically combined plant moisturizing active matter, amino acid moisturizing ingredient, ceramide type skin repair ingredient, is disappeared with meeting
The various skin care item of the person of expense select demand.
It is a further object of the present invention to provide a kind of preparation methods for the Essence for having and continuing moistening effect.
To solve the above problems, the present invention uses following technical scheme:
A kind of Essence with long-acting moisture-keeping efficacy, the Essence contains long-acting moisturizing complexing agent, by quality percentage
Than meter, the long-acting moisturizing complexing agent is made of following components:
As priority, by mass percentage, the long-acting moisturizing complexing agent is made of following components:
The Essence also contain other raw materials, including solvent, thickener, pH adjusting agent, skin conditioning agent, preservative,
Aromatic, by mass percentage, the Essence are made of following raw material components:
Deionized water surplus.
Preferably, by mass percentage, the Essence is made of following raw material components:
Deionized water surplus.
Furthermore, the solvent is water and alcohol mixture, and the alcohol preferably is selected from glycerine, butanediol, sorb (sugar)
One kind in alcohol, polyethylene glycol -32 or their mixture.
The thickener of the Essence preferably is selected from carbomer, xanthans, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters
One kind in cross-linked polymer or their mixture.
The pH adjusting agent of the Essence preferably is selected from one kind in triethanolamine, citric acid, sodium citrate or theirs is mixed
Close object.Between control Essence pH ranging from 5.5-6.5.
The skin conditioning agent of the Essence preferably is selected from hydrolecithin, double-PEG-18 methyl ethers dimethylsilanes, palm
Acyl tripeptides -1, palmityl tetrapeptide -7, one kind in sodium lactate or their mixture.The skin conditioning agent control Essence
Between pH ranging from 5.5-6.5.
The preservative of the Essence preferably is selected from one or both of methyl hydroxybenzoate, Phenoxyethanol.
In addition, the present invention also provides the preparation methods of the above-mentioned Essence with long-acting moisture-keeping efficacy, including walk as follows
Suddenly:
1) the A item components of 80-95% by mass percentage, are weighed:Solvent, thickener, preservative, are uniformly mixed;
2) the B item components of 0.1-0.5% by mass percentage, are weighed:PH adjusting agent, for use;
3) the C item components of 5-18% by mass percentage, are weighed:Long-acting moisturizing complexing agent, skin conditioning agent, aromatic,
It is uniformly mixed, for use;
4) A components are heated to 80-85 DEG C, insulated and stirred cools down after 30 minutes;
5) 45 DEG C are cooled to, B components, C components are added, are stirred until homogeneous.
Preferably, the A component includes:Water (To 100%), glycerine (2-5%), butanediol (3-6%), sorb
(sugar) alcohol (1-3%), carbomer (0.1-0.3%), xanthans (0.1-0.3%), methyl hydroxybenzoate (0.1-0.3%), benzene oxygen second
Alcohol (0.2-0.5%);
The B component:Triethanolamine (0.1-0.3%), citric acid (0.01-0.03%), sodium citrate (0.04-
0.1%);
The C component:Mel extract (1-3%), Acer negundo extract (1-4%), saccharomycete/rice fermentation product filter
Liquid (1-4%), arginine HCl (0.05-0.5%), lysine HCl (0.05-0.5%), ornithine HCl (0.05-0.5%),
Cer NP (0.05-0.5%), Cer AP II (0.05-0.5%), Cer EOS (0.05-0.5%), lauroyl breast
Acyl lactylate (1-5%), phytosphingosine (0.1-0.5%), cholesterine (0.1-0.5%), hydrolecithin (0.1-1%),
Palmityl tripeptides -1 (0.05-0.5%), palmityl tetrapeptide -7 (0.05-0.5%), essence (0.05-0.5%).
The property of important source material used in the present invention is as follows:
Mel extract (Melhydran LS 9876/BASF):Mel extract mainly plays length in keratoderma
Imitate moisture-keeping function.The component of the natural moisturizing factor NMF of Mel extract and human body is very close, rich in amino acid, oligosaccharides, has
The minerals such as machine acid, vitamin, calcium, magnesium, sodium, potassium, nutrition is provided for skin.It is wherein rich in abundant organic acid, it can be rapid soft
The cutin for changing dry hardening, restores the elasticity and flexibility of skin.There is oligosaccharides long-acting moistening effect, lockable moisture to improve
Skin hydration rate reduces water loss in skin.
Acer negundo (ACER SACCHARUM) extract (Maple Water/ICHIMARU):It is derived from Quebec, Canada portion
The Normal juice (age of tree 40 years or more, tree-walk 20CM or more) of region-by-region sugar maple tree trunk, rich in polysaccharide, Ca, K, Mg, Mn, malic acid,
Promote fibroblast proliferation, so as to improve cell water content, skin transepidermal water loss, water content of stratum corneum is improved, in skin
Outermost layer --- enhance skin barrier function in terms of the water of cuticula.
Saccharomycete/rice fermentation Product filtrate (ferment filtrate FC01/ Angel Yeast Co., Ltd):It is selected to originate from north
The organic glutinous rice in Zhongxiang City of township of 30 ° of longevities of latitude, ferments through unartificial yeast, containing abundant oligosaccharides, organic acid (tartaric acid), amino
Acid, small-molecule peptide etc. can enter skin corium quickly through cutin lamellar spacing, promote fibroblastic activity and collagen egg
In vain, elastic fibers and hyaluronic acid hyperplasia, active cell film water channel protein, endogenous increase the water content of skin.
Cer NP, Cer AP II, Cer EOS (SK-Influx/EVONIK):Ceramide is also known as neurolemma
Lipid is a kind of lipid for being present in skin, and the barrier of one layer of waterproof is formed in skin surface.When skin occur drying, furfur,
Cracking phenomena, when barrier function is substantially reduced, skin supplement ceramide can restore rapidly moisturizing and barrier function.The present invention
Ceramide used is originated from tonka bean, the biotechnology production through saccharomycetes to make fermentation, with naturally occurring god in application on human skin
Double-deck stereo chemical constitution through amide is consistent, to enhance skin barrier function in terms of the property of fat source.
The beneficial effects of the present invention are:
1) Essence of the invention combines plant moisturizing active matter, amino acid is protected due to containing long-acting moisturizing complexing agent
Wet ingredient, ceramide type skin repair ingredient can fast lifting keratodermas from water and fat source property angle on both side
Hydration content (CAP), significantly reduce keratoderma water loss rate (TEWL), maintain the water and oil balance of skin.Single makes
With after 4-8 hours, still there is good moistening effect.
2) technical scheme of the present invention as a whole, is used in conjunction with each other, by optimizing constituent content so that final
Formula reach said effect.
Specific implementation mode
Below by specific preferred embodiment combination effete test embodiment, technical scheme of the present invention is made further specific
Illustrate, but the present invention is not limited in following embodiment.
A kind of Essence with long-acting moisture-keeping efficacy disclosed by the invention, containing long-acting moisturizing complexing agent, by quality hundred
Divide than meter, the long-acting moisturizing complexing agent includes:The Mel extract of 10-25%, Acer negundo extract, the 15-30% of 20-40%
Saccharomycete/rice fermentation Product filtrate, 0.5-5% arginine HCl, 0.5-5% lysine HCl, 0.5-5% bird ammonia
The moon of the Cer NP of sour HCl, 0.5-5%, the Cer EOS of Cer AP II, 0.5-5% of 0.5-5%, 10-20%
The cholesterine of osmanthus acyl dilactic acid sodium, the phytosphingosine of 0.5-5%, 0.5-5%.The Essence of the present invention is grown by optimizing
The compounding and adding proportion of moisturizing complexing agent are imitated, there is the moistening effect up to 4-8h.
Embodiment 1
A kind of Essence with long-acting moisture-keeping efficacy, by mass percentage, the Essence is by following raw material components
It constitutes:
A components:Water (To 100%), glycerine (3%), butanediol (5%), sorb (sugar) alcohol (2%), carbomer
(0.15%), xanthans (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%);
B components:Triethanolamine (0.15%), citric acid (0.02%), sodium citrate (0.08%);
C components:Mel extract (1.08%), Acer negundo extract (1.8%), saccharomycete/rice fermentation Product filtrate
(1.32%), arginine HCl (0.06%), lysine HCl (0.06%), ornithine HCl (0.06%), Cer NP
(0.24%), Cer AP II (0.12%), Cer EOS (0.12%), lauroyl dilactic acid sodium (0.9%), plant sheath
Ammonia alcohol (0.12%), cholesterine (0.12%), hydrolecithin (0.5%), palmityl tripeptides -1 (0.1%), palmityl tetrapeptide -
7 (0.1%), essence (0.06%).
The preparation method of the above-mentioned Essence with long-acting moisture-keeping efficacy, includes the following steps:
1) A components by mass percentage, are weighed:Solvent (water, glycerine, butanediol, sorb (sugar) alcohol), thickener (card
Wave nurse, xanthans), preservative (methyl hydroxybenzoate, Phenoxyethanol) is uniformly mixed;
2) B components by mass percentage, are weighed:PH adjusting agent (triethanolamine, citric acid, sodium citrate), for use;
3) C components by mass percentage, are weighed:Long-acting moisturizing complexing agent (Mel extract, Acer negundo extract, yeast
Bacterium/rice fermentation Product filtrate, arginine HCl, lysine HCl, ornithine HCl, Cer NP, Cer AP II, nerve
Amide 1, lauroyl dilactic acid sodium, phytosphingosine, cholesterine), skin conditioning agent (hydrolecithin, palmityl tripeptides -1,
Palmityl tetrapeptide -7), aromatic (essence GGC-49412), be uniformly mixed to it is transparent, for use;
4) A components are heated to 80-85 DEG C, insulated and stirred cools down after 30 minutes;
5) 45 DEG C are cooled to, B components, C components are added, are stirred until homogeneous transparent.
Embodiment 2
A kind of Essence with long-acting moisture-keeping efficacy, by mass percentage, the Essence is by following raw material components
It constitutes:
A components:Water (To 100%), glycerine (3%), butanediol (5%), sorb (sugar) alcohol (2%), carbomer
(0.15%), xanthans (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%);
B components:Triethanolamine (0.15%), citric acid (0.02%), sodium citrate (0.08%);
C components:Mel extract (1.44%), Acer negundo extract (2.4%), saccharomycete/rice fermentation Product filtrate
(1.76%), arginine HCl (0.08%), lysine HCl (0.08%), ornithine HCl (0.08%), Cer NP
(0.32%), Cer AP II (0.16%), Cer EOS (0.16%), lauroyl dilactic acid sodium (1.2%), plant sheath
Ammonia alcohol (0.16%), cholesterine (0.16%), hydrolecithin (0.5%), palmityl tripeptides -1 (0.1%), palmityl tetrapeptide -
7 (0.1%), essence (0.06%).
The Essence preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Embodiment 3
A kind of Essence with long-acting moisture-keeping efficacy, by mass percentage, the Essence is by following raw material components
It constitutes:
A components:Water (To 100%), glycerine (3%), butanediol (5%), sorb (sugar) alcohol (2%), carbomer
(0.15%), xanthans (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%);
B components:Triethanolamine (0.15%), citric acid (0.02%), sodium citrate (0.08%);
C components:Mel extract (1.8%), Acer negundo extract (3%), saccharomycete/rice fermentation Product filtrate
(2.2%), arginine HCl (0.1%), lysine HCl (0.1%), ornithine HCl (0.1%), Cer NP (0.4%),
Cer AP II (0.2%), Cer EOS (0.2%), lauroyl dilactic acid sodium (1.5%), phytosphingosine
(0.2%), cholesterine (0.2%), hydrolecithin (0.5%), palmityl tripeptides -1 (0.1%), palmityl tetrapeptide -7
(0.1%), essence (0.06%).
The Essence preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Embodiment 4
A kind of Essence with long-acting moisture-keeping efficacy, by mass percentage, the Essence is by following raw material components
It constitutes:
A components:Water (To 100%), glycerine (3%), butanediol (5%), sorb (sugar) alcohol (2%), carbomer
(0.15%), xanthans (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%);
B components:Triethanolamine (0.15%), citric acid (0.02%), sodium citrate (0.08%);
C components:Mel extract (2.16%), Acer negundo extract (3.6%), saccharomycete/rice fermentation Product filtrate
(2.64%), arginine HCl (0.12%), lysine HCl (0.12%), ornithine HCl (0.12%), Cer NP
(0.48%), Cer AP II (0.24%), Cer EOS (0.24%), lauroyl dilactic acid sodium (1.8%), plant sheath
Ammonia alcohol (0.24%), cholesterine (0.24%), hydrolecithin (0.5%), palmityl tripeptides -1 (0.1%), palmityl tetrapeptide -
7 (0.1%), essence (0.06%).
The Essence preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Control group 1:
Commercially available certain brand Essence N (being free of long-acting moisturizing complexing agent).
Effect example 1:Security test
Reference《Cosmetics safety technical specification》(version in 2015) Part V human skin enclosed type patch experimental method,
30 volunteers are chosen, takes each embodiments of above-mentioned 1-4 and blank control group (deionized water) sample to synchronize and carries out enclosed type spot
Patch test, is showed no rubefaction or the allergic phenomenas such as erythema (being shown in Table 1) occurs, illustrate essence made from various embodiments of the present invention
Liquid is safe, does not cause any bad phenomenon.
1 enclosed type patch test result of table
Effect example 2:Moistening effect tests (8h)
With reference to QB/T 4256-2011 cosmetics moisture-keeping efficacy evaluation guides, each sample chooses 20 testers, takes
It states the sample amounts in each embodiments of 1-4 and control group and is applied to forearm delineation position.Using instrument MOISTUREMETERSC
MSC1212 (DELFIN) and instrument TAPOMETER SWL5167 (DELFIN) is measured respectively (is not used sample using 0h after sample
Initial value), 0.5h, 1h, 2h, 4h, 8h keratoderma hydration content and percutaneous water loss rate score, record institute total
It is worth and calculates average value, the results are shown in Table 2 and table 3.
2 keratoderma hydration content (a.u) of table
Time | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Control group N |
0h | 21.12 | 21.08 | 20.63 | 20.40 | 21.31 |
0.5h | 35.59 | 43.44 | 45.56 | 46.62 | 45.37 |
1h | 50.11 | 65.62 | 67.34 | 69.74 | 62.88 |
2h | 59.28 | 72.38 | 75.13 | 76.86 | 55.32 |
4h | 45.07 | 59.97 | 62.24 | 64.30 | 36.70 |
8h | 38.37 | 50.05 | 54.98 | 55.21 | 30.49 |
The percutaneous water loss rate (g/m of 3 skin of table2h)
Time | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Control group N |
0h | 9.38 | 9.41 | 9.50 | 9.55 | 9.32 |
0.5h | 6.19 | 5.63 | 5.46 | 5.54 | 5.57 |
1h | 5.28 | 3.56 | 3.37 | 3.26 | 3.85 |
2h | 4.87 | 2.92 | 2.69 | 2.56 | 5.15 |
4h | 5.42 | 4.07 | 3.81 | 3.70 | 6.24 |
8h | 6.10 | 5.29 | 5.04 | 5.01 | 8.19 |
As shown in Table 2:1-4 of the embodiment of the present invention, after using sample 2h, keratoderma hydration content is quick
It is promoted, and reaches maximum value after 2h, wherein embodiment 3 and 4 is respectively 75.13 and 76.86 in the maximum value of 2h, is divided after 4-8h
54.98 and 55.21 are not fallen back to.And then the cuticula hydration content after using 1h reaches maximum value 62.88 to control group N, then
Gradually start to fall after rise, drops to 30.49 after 8h.Therefore, various embodiments of the present invention, by optimizing answering for long-acting moisturizing complexing agent
Match and adding proportion has more efficient more significant moistening effect compared with control group N.
From the result of table 3 can with it is further seen that:2-4 of the embodiment of the present invention is after using sample 2h, the percutaneous moisture of skin
Turnover rate is reduced to the sections 2.5-3.0, after 8h, and gradually goes back up to the sections 5.0-5.5.And after using control group N samples 1h, skin
The percutaneous water loss rate of skin is then reduced within the scope of 3.5-4.0, then bottom out, after 8h, and gradually goes back up to the areas 8.0-8.5
In, illustrate that control group M does not have the effect of long-acting moisturizing.
And the essence liquid product of the embodiment of the present invention 1-4 still maintains the percutaneous moisture of lower skin after 4-8h
Turnover rate, this further illustrates the present invention each embodiment, after adding long-acting moisturizing complexing agent and optimizing adding proportion, has more
Lengthen the moistening effect of effect.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore
It is every without departing from technical solution of the present invention content, simply repaiied to any made by above example according to the technical essence of the invention
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (8)
1. a kind of Essence with long-acting moisture-keeping efficacy, it is characterised in that:The Essence contains long-acting moisturizing complexing agent, presses
Mass percent meter, the long-acting moisturizing complexing agent are made of following components:
2. the Essence according to claim 1 with long-acting moisture-keeping efficacy, it is characterised in that:The long-acting moisturizing is compound
Agent is made of following components:
3. the Essence according to claim 1 or 2 with long-acting moisture-keeping efficacy, it is characterised in that:The Essence is also
Containing other raw materials, including solvent, thickener, pH adjusting agent, skin conditioning agent, preservative, solubilizer, aromatic, by quality
Percentages, the Essence are made of following raw material components:
4. the Essence according to claim 3 with long-acting moisture-keeping efficacy, it is characterised in that:By mass percentage,
The Essence is made of following raw material components:
5. the Essence according to claim 4 with long-acting moisture-keeping efficacy, it is characterised in that:The solvent is water and alcohol
Mixture, the alcohol are selected from glycerine, butanediol, sorb (sugar) alcohol, one kind in polyethylene glycol -32 or their mixture;
The thickener is selected from carbomer, xanthans, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers
A kind of or their mixture;
The one kind or their mixture of the pH adjusting agent in triethanolamine, citric acid, sodium citrate;
The skin conditioning agent is selected from hydrolecithin, double-PEG-18 methyl ethers dimethylsilanes, palmityl tripeptides -1, palm
One kind in acyl tetrapeptide -7, sodium lactate or their mixture;
The preservative is selected from one or both of methyl hydroxybenzoate, Phenoxyethanol.
6. the Essence according to claim 5 with long-acting moisture-keeping efficacy, it is characterised in that:The skin conditioning agent control
Between the pH of Essence processed ranging from 5.5-6.5.
7. the preparation method of the Essence with long-acting moisture-keeping efficacy described in any one of claim 3-6, which is characterized in that
Include the following steps:
1) the A item components of 80-95% by mass percentage, are weighed:Solvent, thickener, preservative, are uniformly mixed;
2) 0.1-0.5%B components by mass percentage, are weighed:PH adjusting agent, for use;
3) the C item components of 5-18% by mass percentage, are weighed:Long-acting moisturizing complexing agent, skin conditioning agent, aromatic, stirring
It is uniformly mixed, for use;
4) A components are heated to 80-85 DEG C, insulated and stirred cools down after 30 minutes;
5) 45 DEG C are cooled to, B components, C components are added, are stirred until homogeneous.
8. the preparation method of the Essence according to claim 7 with long-acting moisture-keeping efficacy, it is characterised in that:
The A component include:Water (To 100%), glycerine (2-5%), butanediol (3-6%), sorb (sugar) alcohol (1-3%),
Carbomer (0.1-0.3%), xanthans (0.1-0.3%), methyl hydroxybenzoate (0.1-0.3%), Phenoxyethanol (0.2-0.5%);
The B component:Triethanolamine (0.1-0.3%), citric acid (0.01-0.03%), sodium citrate (0.04-0.1%);
The C component:Mel extract (1-3%), Acer negundo extract (1-4%), saccharomycete/rice fermentation Product filtrate
(1-4%), arginine HCl (0.05-0.5%), lysine HCl (0.05-0.5%), ornithine HCl (0.05-0.5%), god
Through amide 3 (0.05-0.5%), Cer AP II (0.05-0.5%), Cer EOS (0.05-0.5%), lauroyl lactoyl
Sodium lactate (1-5%), phytosphingosine (0.1-0.5%), cholesterine (0.1-0.5%), hydrolecithin (0.1-1%), palm fibre
Palmitic acid acyl tripeptides -1 (0.05-0.5%), palmityl tetrapeptide -7 (0.05-0.5%), essence (0.05-0.5%).
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109381358A (en) * | 2018-12-13 | 2019-02-26 | 上海尚颜进出口贸易有限公司 | A kind of replenishing water and preserving moisture facial mask liquor manufacture method |
CN111228209A (en) * | 2020-03-19 | 2020-06-05 | 广东鑫美鑫化妆品有限公司 | Cosmetic composition, preparation method and application thereof, and cosmetic essence |
CN112494399A (en) * | 2020-12-14 | 2021-03-16 | 广州欧正化妆品技术研究院有限公司 | Moisturizing skin-brightening repair essence containing saccharomycete rice fermentation product filtrate and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105326678A (en) * | 2015-10-28 | 2016-02-17 | 嘉兴市蝶柔化妆品有限公司 | Multi-effect ceramide face cream |
CN106109392A (en) * | 2016-06-27 | 2016-11-16 | 上海乐宝日化股份有限公司 | Biofibre facial mask |
-
2018
- 2018-07-02 CN CN201810706695.3A patent/CN108451892B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105326678A (en) * | 2015-10-28 | 2016-02-17 | 嘉兴市蝶柔化妆品有限公司 | Multi-effect ceramide face cream |
CN106109392A (en) * | 2016-06-27 | 2016-11-16 | 上海乐宝日化股份有限公司 | Biofibre facial mask |
Non-Patent Citations (1)
Title |
---|
裘炳毅等: "《现代化妆品科学与技术 中》", 31 March 2016 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109381358A (en) * | 2018-12-13 | 2019-02-26 | 上海尚颜进出口贸易有限公司 | A kind of replenishing water and preserving moisture facial mask liquor manufacture method |
CN111228209A (en) * | 2020-03-19 | 2020-06-05 | 广东鑫美鑫化妆品有限公司 | Cosmetic composition, preparation method and application thereof, and cosmetic essence |
CN112494399A (en) * | 2020-12-14 | 2021-03-16 | 广州欧正化妆品技术研究院有限公司 | Moisturizing skin-brightening repair essence containing saccharomycete rice fermentation product filtrate and preparation method thereof |
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