CN107982168A - Lipstick containing stem cell secretion factors - Google Patents

Lipstick containing stem cell secretion factors Download PDF

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Publication number
CN107982168A
CN107982168A CN201711299092.8A CN201711299092A CN107982168A CN 107982168 A CN107982168 A CN 107982168A CN 201711299092 A CN201711299092 A CN 201711299092A CN 107982168 A CN107982168 A CN 107982168A
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CN
China
Prior art keywords
lipstick
parts
stem cell
skin
tetrapeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201711299092.8A
Other languages
Chinese (zh)
Inventor
葛啸虎
陈海佳
王飞
王一飞
王小燕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Saliai StemCell Science and Technology Co Ltd
Original Assignee
Guangzhou Saliai StemCell Science and Technology Co Ltd
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Filing date
Publication date
Application filed by Guangzhou Saliai StemCell Science and Technology Co Ltd filed Critical Guangzhou Saliai StemCell Science and Technology Co Ltd
Priority to CN201711299092.8A priority Critical patent/CN107982168A/en
Publication of CN107982168A publication Critical patent/CN107982168A/en
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a lipstick containing stem cell secretion factors, which comprises beeswax, jojoba oil, shea butter, a plant extract, glycerol, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, acetyl tetrapeptide-5, stem cell secretion factors and hyaluronic acid. The lipstick provided by the invention can rapidly supplement nutrition and moisture of lip skin, can keep moisture for a long time, and can repair lip skin damage, improve skin immunity and enhance the tolerance and resistance of the skin to the external environment.

Description

A kind of lipstick containing stem cell secretion factor
Technical field
The present invention relates to cosmetic technical field, more particularly, to a kind of lipstick containing stem cell secretion factor.
Background technology
Lipstick is the common cosmetics of modern female, and one layer of just right lipstick is applied on lip can make one to seem especially It is coquettish.The color saturation of lipstick is high, and color mileage is strong, and due to being that solid is generally not easy since cheilogramma is too deep and outer Overflow, commonly use it to modify lip, lip color.
Most of lipstick currently on the market is all to form one layer of tempered oil film on the surface of lip, although lip can be supplemented Moisture, and there is certain moistening effect, but its gas permeability is excessively poor, and skin of lip can not breathe, and also can not directly improve dry Dry impaired lip skin, also influences the eubolism of lip skin, can not comprehensively improve lip due to environment, season, day Caused by the reasons such as gas the problems such as drying, cracking, decortication, pain, tarnish etc..
The content of the invention
In view of this, it is an object of the invention to provide a kind of lipstick containing stem cell secretion factor, the lipstick to supplement While lip moisture, moisturizing, moreover it is possible to repair impaired lip skin, improve the immunity of lip Skin Cell.
To achieve the above object, the present invention provides a kind of lipstick containing stem cell secretion factor, it includes beeswax, lotus lotus Bar oil, shea butter, plant extracts, glycerine, palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell point Secrete the factor, and hyaluronic acid.
Preferably, by weight, the lipstick includes following components:70-80 parts of beeswaxs, 5-10 parts of SIMMONDSIA CHINENSIS SEED OILs, 5- 10 parts of shea butters, 0.5-1.0 parts of plant extracts, 5-10 parts of glycerine, 0.2-0.6 parts of palmityl tetrapeptide -7,0.3-0.5 part palm fibres Palmitic acid acyl tripeptides -5,0.2-0.4 part acetyl group tetrapeptide -5,0.05-0.15 part stem cell secretion factor, and 0.05-0.3 parts of hyalomitomes Acid.
Preferably, by weight, the lipstick includes following components:75-80 parts of beeswaxs, 6-8 parts of SIMMONDSIA CHINENSIS SEED OILs, 6-8 Part shea butter, 0.8-1.0 parts of plant extracts, 6-8 parts of glycerine, 0.2-0.5 parts of palmityl tetrapeptide -7,0.3-0.4 part palms Acyl tripeptides -5,0.2-0.3 part acetyl group tetrapeptide -5,0.1-0.15 part stem cell secretion factor, and 0.15-0.3 parts of hyaluronic acids.
Preferably, the plant extracts is one in Rosmarinus officinalis extract, bamboo extractive, pot marigold extract Kind is a variety of.
Preferably, by weight, the lipstick further includes 0.5-1.5 parts of antioxidants.
Preferably, the antioxidant is one in TBHQ, butylated hydroxy anisole, dibutyl hydroxy toluene, VE Kind is a variety of.
Preferably, in parts by weight, the lipstick further includes 1.5-2.5 parts of preservative.
Preferably, the preservative is one kind in Phenoxyethanol, methyl hydroxybenzoate, ethyl hydroxy benzoate, and Nipasol It is or a variety of.
The lipstick containing stem cell secretion factor provided according to the present invention, wherein contain beeswax, SIMMONDSIA CHINENSIS SEED OIL, breast wood fruit Oil, plant extracts, glycerine and hyaluronic acid, can supplement nutrition and the moisture of lip skin, and lasting moisturizing rapidly, be double Lip pins moisture and provides barrier, meanwhile, also contain palmityl tetrapeptide -7 in the lipstick, palmityl tripeptides -5 and acetyl group tetrapeptide - 5, it can repair the damage of lip skin, effectively moist lip skin, while coordinate stem cell secretion factor, repair skin damage While wound, additionally it is possible to improve the immunity of skin, strengthen tolerance and resistance of the skin to external environment, so that comprehensively Improve lip due to drying, cracking, decortication, pain, tarnish etc. caused by the reasons such as environment, season, weather the problems such as.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description Obtain substantially, or recognized by the practice of the present invention.
Embodiment
In order to better illustrate the present invention, with reference to specific embodiment, the present invention will be further described.It is appreciated that , these specific embodiments are exemplary, are only used for explaining the present invention, and are not considered as limiting the invention.
The embodiment of the present invention provides a kind of lipstick containing stem cell secretion factor, which includes beeswax, SIMMONDSIA CHINENSIS SEED OIL, Shea butter, plant extracts, glycerine, palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion because Son, and hyaluronic acid.
In the formula of lipstick provided by the invention, beeswax can play the role of nourishing and protection lip, have outstanding Moisture-keeping efficacy, lip moisture can be kept not to be lost in, reduce the dry and cracked symptom of lip lip appearance.In addition also have in beeswax more The kind important component beneficial to skin of lip, is conducive to absorption of the people to these nutritional ingredients.SIMMONDSIA CHINENSIS SEED OIL has good Permeability, containing abundant vitamin D and protein, is good moist and moisturizing oil, can safeguard lip skin moisture, pre- wrinkle resistant Line and softening lip skin.Shea butter has splendid humectant properties, containing the three fat component of vegetable glycerides being in admirable proportion, And be conducive to safeguard the stability of formula, increase formula system viscosity and pliability so that formula is more stable, provides cutaneous sense Characteristic.Plant extracts contains the nutritional ingredient needed for abundant skin, can supplement skin nutrition, recovers elasticity of skin.Thoroughly Bright matter acid can help skin to draw substantial amounts of moisture, can be with moment deep moisturizing, increase skin elasticity and tension force, and can Contribute to the normal oil-water balance of recovery skin, improve drying machine relaxation skin.Taurine is acted on extraordinary skin-active, can To strengthen transdermal absorption factor of the skin to various nutrients, and it is capable of providing the lasting moisture-retaining capacity of skin.Therefore, the present invention carries The lipstick of confession can supplement lip skin moisture, and permanent moisturizing, increase elasticity rapidly.
Meanwhile also contain palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group four in the formula of lipstick provided by the invention Peptide -5, stem cell secretion factor.
Wherein, palmityl tetrapeptide -7 be it is a kind of victory peptide is synthesized by four Amino acid profiles, can delay and suppress excessive The generation of interleukin, so as to suppress some unnecessary inappropriate inflammatory reactions and glycosylation damage, has significant anti- The effect of edema, anti-inflammatory, can strengthen tolerance of the skin to external environment.Meanwhile it can also stimulate dermal layer of the skin Middle collagen (I types, II type, IV type) and the synthesis and development of elastin laminin, reach the effect of compacting with plentiful skin.Palm Acyl tripeptides -5 can promote the synthesis of collagen (I types, II type familial combined hyperlipidemia) and extracellular by increasing stroma cell activity The generation of stromatin, strengthens connective tissue, promotes cytoactive, while protects collagen not by matrix metalloproteinase point Solution, both act synergistically, are effectively improved skin quality, allow skin to seem high resilience.Acetyl tetrapeptide -5 can suppress saccharification, So as to reduce being cross-linked with each other for collagen, the effect of reaching mitigation and resist wrinkle, the elasticity and smoothness of skin are improved.
Stem cell secretion factor contains the extremely strong growth factor of a large amount of physiological actions, can activate in vivo in a dormant state Various stem cells, supplement various fresh cells for body, substitute aging and impaired cell, and then repair skin damage Wound, wrinkle reduction, makes skin reach the state of overall rejuvenation.Meanwhile stem cell secretion factor is also containing being improved immunity The factor, can stimulate leucocyte to regenerate, and improve cutaneous immunisation power, and then improve tolerance and resistance of the skin to adverse circumstances Power, is significantly reduced the generation of skin problem.
Therefore, lipstick provided by the invention can repair the damage of lip skin, while skin injury is repaired, moreover it is possible to The immunity of lip skin is enough improved, strengthens tolerance and resistance of the lip skin to external environment, so as to comprehensively improve Lip is due to drying, cracking, decortication, pain, tarnish etc. caused by the reasons such as environment, season, weather the problems such as.
It is understood that palmityl tetrapeptide -7 in the present invention, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell Secretion factor can be prepared using method commonly used in the art, this is not described in detail in the present invention.
In some embodiments of the invention, by weight, the lipstick includes following components:70-80 parts of beeswaxs, 5- 10 parts of SIMMONDSIA CHINENSIS SEED OILs, 5-10 parts of shea butters, 0.5-1.0 parts of plant extracts, 5-10 parts of glycerine, 0.2-0.6 parts of palmityls four Peptide -7,0.3-0.5 part palmityl tripeptides -5,0.2-0.4 part acetyl group tetrapeptide -5,0.05-0.15 part stem cell secretion factor, and 0.05-0.3 parts of hyaluronic acids.Preferably, the present invention other embodiments in, by weight, the lipstick include with Lower component:75-80 parts of beeswaxs, 6-8 parts of SIMMONDSIA CHINENSIS SEED OILs, 6-8 parts of shea butters, 0.8-1.0 parts of plant extracts, 6-8 parts of glycerine, 0.2-0.5 parts of palmityl tetrapeptide -7,0.3-0.4 part palmityl tripeptides -5,0.2-0.3 part acetyl group tetrapeptides -5,0.1-0.15 part Stem cell secretion factor, and 0.15-0.3 parts of hyaluronic acids.
Plant extracts contains the nutrient needed for various skins, can supplement skin-nourishing.It is it is understood that of the invention The species of plant extracts is not particularly limited, can be plant extracts commonly used in the art, for example, the one of the present invention In a little embodiments, the plant extracts be one kind in Rosmarinus officinalis extract, bamboo extractive, pot marigold extract or It is a variety of.It can also be appreciated that the material such as the Rosmarinus officinalis extract in the present invention, bamboo extractive, pot marigold extract is equal It can be prepared using method commonly used in the art, this is not described in detail in the present invention.
In some embodiments of the invention, antioxidant can also be added with lipstick provided by the invention.It can manage Solution, the present invention are not particularly limited the species of antioxidant, it can be various antioxidants commonly used in the art, example Such as, in some embodiments of the invention, antioxidant is selected from TBHQ, butylated hydroxy anisole, dibutyl hydroxy toluene, VE In one or more.In some embodiments of the invention, by weight, the content of the antioxidant is 0.5-1.5 Part.
In some embodiments of the invention, in parts by weight, 0.5-2.5 can also be contained in lipstick provided by the invention The preservative of part.Can be commonly used in the art each it is understood that the present invention is not particularly limited the species of preservative Kind preservative, for example, the one or more in Phenoxyethanol, methyl hydroxybenzoate, ethyl hydroxy benzoate, and Nipasol etc..
The lipstick containing stem cell secretion factor provided according to the present invention, can use this area routine method preparation and , the application no longer repeats this.
The lipstick containing stem cell secretion factor provided according to the present invention, wherein contain beeswax, SIMMONDSIA CHINENSIS SEED OIL, breast wood fruit Oil, plant extracts, glycerine and hyaluronic acid, can supplement nutrition and the moisture of skin, and lasting moisturizing rapidly, be locked for lips Firmly moisture provides barrier, meanwhile, palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5 are also contained in the lipstick, its The damage of lip skin can be repaired, effectively moist lip skin, while coordinate stem cell secretion factor, repairing skin injury At the same time, additionally it is possible to improve the immunity of skin, strengthen tolerance and resistance of the skin to external environment, so as to comprehensively improve Lip is due to drying, cracking, decortication, pain, tarnish etc. caused by the reasons such as environment, season, weather the problems such as.
The invention is further illustrated by the following examples, but the embodiment is merely to illustrate the present invention rather than limitation The present invention.
Formula as described in table 1 prepares lipstick, then carries out using effect test and carries out effect statistics.
Table 1
The method of using effect test:
60 female volunteers are selected, age distribution is 25-40 Sui, is randomly divided into six groups, every group 10 of A, B, C, D, E, F People.Wherein A groups are respectively respectively made sooner or later daily using the lipstick once prepared by formula 1 in the above-mentioned table 1 of the present invention, B groups sooner or later daily With once by being formulated 2 lipsticks prepared in the above-mentioned table 1 of the present invention, C groups respectively use sooner or later daily matches somebody with somebody in once above-mentioned table 1 of the invention Lipstick prepared by side 3, the D groups lipstick that the morning and evening is respectively prepared using formula 4 in once above-mentioned table 1 of the invention daily, E groups are daily sooner or later Each lipstick prepared using formula 5 in once above-mentioned table 1 of the invention, F groups are daily sooner or later respectively using once conventional lipstick, difference Lip wrinkle of skin situation is detected after being used continuously 8 weeks, while lip wrinkle of skin situation is detected after disabling 8 weeks.
Table 2
Can be seen that the lipstick provided by the invention containing stem cell secretion factor from the using effect in upper table can supplement Lip skin moisture, recovers lip skin water profit elasticity, while can also repair the damage of lip skin, and enhancing lip skin is to extraneous ring The tolerance and resistance in border, thus comprehensively improve lip is dry caused by the reasons such as environment, season, weather, crack, The problems such as decortication, pain, tarnish etc..
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that:Not In the case of departing from the principle of the present invention and objective a variety of change, modification, replacement and modification can be carried out to these embodiments, this The scope of invention is limited by claim and its equivalent.

Claims (8)

1. a kind of lipstick containing stem cell secretion factor, it is characterised in that the lipstick includes beeswax, SIMMONDSIA CHINENSIS SEED OIL, breast wood fruit Oil, plant extracts, glycerine, palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, and thoroughly Bright matter acid.
2. lipstick as claimed in claim 1, it is characterised in that by weight, the lipstick includes following components:70-80 Part beeswax, 5-10 parts of SIMMONDSIA CHINENSIS SEED OILs, 5-10 parts of shea butters, 0.5-1.0 parts of plant extracts, 5-10 parts of glycerine, 0.2-0.6 parts Palmityl tetrapeptide -7,0.3-0.5 part palmityl tripeptides -5,0.2-0.4 part acetyl group tetrapeptide -5,0.05-0.15 part stem cell point Secrete the factor, and 0.05-0.3 parts of hyaluronic acids.
3. lipstick as claimed in claim 2, it is characterised in that by weight, the lipstick includes following components:75-80 Part beeswax, 6-8 parts of SIMMONDSIA CHINENSIS SEED OILs, 6-8 parts of shea butters, 0.8-1.0 parts of plant extracts, 6-8 parts of glycerine, 0.2-0.5 parts of palm fibres Palmitic acid acyl tetrapeptide -7,0.3-0.4 part palmityl tripeptides -5,0.2-0.3 part acetyl group tetrapeptide -5,0.1-0.15 part stem cell secretion because Son, and 0.15-0.3 parts of hyaluronic acids.
4. lipstick as claimed in claim 1, it is characterised in that the plant extracts is selected from Rosmarinus officinalis extract, the leaf of bamboo Extract, the one or more in pot marigold extract.
5. lipstick as claimed in claim 1, it is characterised in that by weight, the lipstick further includes 0.5-1.5 parts of antioxygens Agent.
6. lipstick as claimed in claim 5, it is characterised in that the antioxidant be selected from TBHQ, butylated hydroxy anisole, One or more in dibutyl hydroxy toluene, VE.
7. lipstick as claimed in claim 2, it is characterised in that in parts by weight, the lipstick further includes 1.5-2.5 parts anti- Rotten agent.
8. lipstick as claimed in claim 7, it is characterised in that the preservative is selected from Phenoxyethanol, methyl hydroxybenzoate, oxybenzene One or more in ethyl ester, and Nipasol.
CN201711299092.8A 2017-12-08 2017-12-08 Lipstick containing stem cell secretion factors Withdrawn CN107982168A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904897A (en) * 2020-09-16 2020-11-10 上海海盈通感光材料有限公司 Nourishing type lip cosmetic and preparation method thereof
CN114569520A (en) * 2022-04-19 2022-06-03 广州市悦锐生物科技有限公司 Composition for plumping and moistening lips and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068391A (en) * 2010-12-30 2011-05-25 广州赛莱拉化妆品科技有限公司 Application of human steam cell growth factors in cosmetics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068391A (en) * 2010-12-30 2011-05-25 广州赛莱拉化妆品科技有限公司 Application of human steam cell growth factors in cosmetics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
钟星等: "胜肽在化妆品中的应用和最新进展", 《日用化学品科学》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904897A (en) * 2020-09-16 2020-11-10 上海海盈通感光材料有限公司 Nourishing type lip cosmetic and preparation method thereof
CN114569520A (en) * 2022-04-19 2022-06-03 广州市悦锐生物科技有限公司 Composition for plumping and moistening lips and application thereof

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