CN107961198A - Eye cream containing stem cell secretory factors - Google Patents
Eye cream containing stem cell secretory factors Download PDFInfo
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- CN107961198A CN107961198A CN201711297993.3A CN201711297993A CN107961198A CN 107961198 A CN107961198 A CN 107961198A CN 201711297993 A CN201711297993 A CN 201711297993A CN 107961198 A CN107961198 A CN 107961198A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Birds (AREA)
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- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention discloses an eye cream containing stem cell secretion factors, which comprises palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, acetyl tetrapeptide-5, stem cell secretion factors, coix seed extracting solution, red bean extracting solution, saffron extracting solution, hyaluronic acid and deionized water. According to the eye cream disclosed by the invention, the skin injury can be repaired, the eye wrinkles can be removed, meanwhile, the immunity of the eye skin can be improved, the tolerance and the resistance of the skin to the external environment can be enhanced, the effect of rejuvenating the eye skin can be really achieved, and the eye wrinkles can be resisted.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly, to a kind of eye cream containing stem cell secretion factor.
Background technology
Eye skin is the most thin skin of human body, while is the most frequent position of activity again, but also is to pull skin in makeup
The most place of skin number, is very easy to grow wrinkle；And with advancing age, eyes skin of lower eyelid can produce it is loose,
There is fold.The generation of eye microgroove means the exposure at age, therefore eye-care is even more important for women.
Existing eye-care eye cream, normally only has certain moist moisturizing or mitigates the symptoms such as livid ring around eye, pouch
The effect of effect, it improves wrinkle, microgroove, is relatively poor, moreover, existing eye cream on the market is generally the defensive eye cream of physics,
It is only capable of forming one layer of physical protection film on eye skin surface, to resist environmental nuisance, it can not fundamentally improve eye skin
The resistance of skin, to reach the effect that resistance eye wrinkle-removing is produced, slowed down aging.
The content of the invention
In view of this, it is an object of the invention to provide a kind of eye cream containing stem cell secretion factor, the eye cream to repair
Eye skin is damaged, while improving eye wrinkle-removing, moreover it is possible to is improved the immunity of eye skin cell, and then is resisted eye wrinkle-removing
Generation, fundamentally slow down aging.
To achieve the above object, the present invention provides a kind of eye cream containing stem cell secretion factor, including palmityl tetrapeptide-
7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, adlay extracting solution, red bean extracting solution, safflower extraction
Liquid, hyaluronic acid and deionized water.
Preferably, based on 100 parts by weight, the eye cream includes following components：0.5-1.5 parts of palmityl tetrapeptides -7,0.6-
1.0 parts of palmityl tripeptides -5,1.0-1.5 part acetyl group tetrapeptide -5,0.2-0.5 part stem cell secretion factors, 2-4 parts of adlay extractions
Liquid, 3-5 parts of red bean extracting solutions, 2.5-3.0 parts of crocus sativus, 0.5-1.0 parts of hyaluronic acids and deionized water surplus.
Preferably, based on 100 parts by weight, the eye cream includes following components：0.8-1.2 parts of palmityl tetrapeptides -7,0.7-
0.8 part of palmityl tripeptides -5,1.2-1.4 part acetyl group tetrapeptide -5,0.3-0.4 part stem cell secretion factor, 2.5-3.5 parts of adlays
Extracting solution, 3.5-4.5 parts of red bean extracting solutions, 2.6-2.8 parts of crocus sativus, 0.6-0.8 parts of hyaluronic acids and deionization
Water surplus.
Preferably, the eye cream further includes emulsifying agent, and the emulsifying agent is selected from glyceryl monostearate, cetearyl alcohol
At least one of alcohol, C9-15 alcohol phosphate, laruyl alcohol phosphate and C20-22 alcohol phosphates.
Preferably, in terms of 100 parts by weight, the content of the emulsifying agent is 4-8 parts.
Preferably, the eye cream further includes at least one of vitamin A and vitamin E.
Preferably, in terms of 100 parts by weight, the content of the vitamin A is 0.5-1.5 parts, and the content of the vitamin E is
0.5-1.5 parts.
Preferably, in terms of 100 parts by weight, the eye cream further includes 0.5-2.5 parts of antiseptic.
Preferably, the antiseptic presses 1 for potassium sorbate or pungent glycol with pentanediol:2-1:The Compositional antiseptic agent of 5 compositions.
The eye cream containing stem cell secretion factor provided according to the present invention, wherein containing adlay extracting solution, red bean extracting solution,
Crocus sativus and hyaluronic acid, can supplement eye part skin nutrition and moisture rapidly, recover the elasticity of eye part skin, together
When, also contain palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5 in the eye cream liquid, it can be with restoring ocular skin
Damage, eye wrinkle-removing is dispelled, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to improve eye
The immunity of portion's skin, strengthens tolerance and resistance of the skin to external environment, is really achieved the effect of eye skin rejuvenation
Fruit, so as to resist the generation of eye wrinkle-removing, delays the aging of eye skin.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obtain substantially, or recognized by the practice of the present invention.
Embodiment
In order to better illustrate the present invention, with reference to specific embodiment, the present invention will be further described.It is appreciated that
, these specific embodiments are exemplary, are only used for explaining the present invention, and are not considered as limiting the invention.
The embodiment of the present invention provides a kind of eye cream containing stem cell secretion factor, which includes palmityl tetrapeptide -7,
Palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, adlay extracting solution, red bean extracting solution, crocus sativus,
Hyaluronic acid and deionized water.
Palmityl tetrapeptide -7 be it is a kind of victory peptide is synthesized by four Amino acid profiles, can delay and to suppress excessive cell white
The generation of interleukin, so as to suppress some unnecessary inappropriate inflammatory reactions and glycosylation damage, there is significant anti-eyelid to float
Effect that is swollen, eliminating pouch, anti-inflammatory, can strengthen tolerance of the skin to external environment.Meanwhile it can also stimulate skin
The synthesis and development of collagen (I types, II type, IV type) and elastin laminin, reach the work(to compact with plentiful skin in skin corium
Effect.Palmityl tripeptides -5 can by increase stroma cell activity promote the synthesis of collagen (I types, II type familial combined hyperlipidemia) and
The generation of extracellular matrix protein, strengthens connective tissue, promotes cytoactive, while protect collagen not by matrix metal egg
White enzyme decomposes, both act synergistically, effective wrinkle reduction, improves skin quality, allows skin to seem more aobvious young and high resilience.Sugar
Collagen is cross-linked with each other used in change, its be produce pouch the reason for one of, acetyl tetrapeptide -5 can suppress saccharification, from
And being cross-linked with each other for collagen is reduced, reach the effect of mitigating pouch and resistance wrinkle, improve the elasticity and smoothness of skin.
Stem cell secretion factor contains the extremely strong growth factor of a large amount of physiological actions, can activate in vivo in a dormant state
Various stem cells, supplement various fresh cells for body, substitute aging and impaired volume cell, and then repair skin damage
Wound, wrinkle reduction, makes skin reach the state of overall rejuvenation.Meanwhile stem cell secretion factor is also containing being improved immunity
The factor, can stimulate leucocyte to regenerate, and improve cutaneous immunisation power, and then improve tolerance and resistance of the skin to adverse circumstances
Power, is significantly reduced the generation of skin problem.
It is understood that palmityl tetrapeptide -7 in the present invention, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell
Secretion factor can be prepared using method commonly used in the art, this is not described in detail in the present invention.
Adlay extracting solution, which has, controls the flat acne of wart, light speckles, beautification and white, moisturizing smoothing wrinkle and other effects, especially contained breaks down proteins
Ferment can soften skin keratin, vitamin E Wheat Protein；Red bean extracting solution has the health-care effects such as detumescence；Safflower
The main component of extracting solution is crocetin and crocin, it has effects that to increase skin elasticity, crease-resistant.Hyaluronic acid energy
The loss of hyaluronic acid, increases the collagen and elastomer in corium, eliminates cutis laxa, subtract in enough rapid supplement skin
Few wrinkle.It can also be appreciated that the adlay extracting solution in the present invention, red bean extracting solution, crocus sativus and transparent
The materials such as matter acid can be prepared using method commonly used in the art, this is not described in detail in the present invention.
In some embodiments of the invention, based on 100 parts by weight, based on 100 parts by weight, the eye cream is included with the following group
Point：0.5-1.5 parts of palmityl tetrapeptide -7,0.6-1.0 part palmityl tripeptides -5,1.0-1.5 part acetyl group tetrapeptides -5,0.2-0.5
Part stem cell secretion factor, 2-4 parts of adlay extracting solutions, 3-5 parts of red bean extracting solutions, 2.5-3.0 parts of crocus sativus, 0.5-
1.0 parts of hyaluronic acids and deionized water surplus.Preferably, in other embodiments of the present invention, based on 100 parts by weight,
The eye cream includes following components：0.8-1.2 parts of palmityl tetrapeptide -7,0.7-0.8 part palmityl tripeptides -5,1.2-1.4 part second
Acyl group tetrapeptide -5,0.3-0.4 part stem cell secretion factor, 2.5-3.5 parts of adlay extracting solutions, 3.5-4.5 parts of red bean extracting solutions,
2.6-2.8 parts of crocus sativus, 0.6-0.8 parts of hyaluronic acids and deionized water surplus.
In some embodiments of the invention, the eye cream can also contain emulsifying agent.It is understood that the present invention is right
The species of emulsifying agent is not particularly limited, it can be various emulsifying agents commonly used in the art, for example, the emulsifying agent can be
In glyceryl monostearate, cetostearyl alcohol, C9-15 alcohol phosphate, laruyl alcohol phosphate and C20-22 alcohol phosphates
It is at least one.In some embodiments of the invention, in terms of 100 parts by weight, the content of the emulsifying agent is 4-8 parts.
In some embodiments of the invention, the eye cream can also be including at least one in vitamin A and vitamin E
Kind.Vitamin is also known as vitamin, has very high security, and both effectiveness very good, can penetrate into epidermis, absorbs and turns into skin
Be changed into VA alcohol, can softening skin cutin, stimulate cell division, activating cell, improve skin elasticity.Vitamin A is a kind of tool
There is the material of retinol bioactivity, it may participate in the synthesis of glycoprotein, this normally forms, develops and maintain ten for epithelium
Divide important；Vitamin E is a kind of liposoluble vitamin, it is easy to it is absorbed by the skin, the metabolic function of skin can be promoted,
Prevent pigment deposition, meanwhile, vitamin E also can inhibit the lipid peroxidation reaction in ocular lens body, make peripheral vasodilation, change
Kind ocular circulation.In some embodiments of the invention, the content of the vitamin A is 0.5-1.5 parts, the vitamin
The content of E is 0.5-1.5 parts.
In some embodiments of the invention, in terms of 100 parts by weight, 0.5- can also be contained in eye cream provided by the invention
2.5 parts of antiseptic.It is understood that the present invention is not particularly limited the species of antiseptic, can be commonly used in the art
Various thickeners, for example, potassium sorbate, pungent glycol, pentanediol etc..In some embodiments of the invention, the antiseptic
For potassium sorbate or pungent glycol 1 is pressed with pentanediol:2-1:The Compositional antiseptic agent of 5 compositions.
The eye cream containing stem cell secretion factor provided according to the present invention, can use this area routine method preparation and
, the application no longer repeats this.
The eye cream containing stem cell secretion factor provided according to the present invention, wherein containing adlay extracting solution, red bean extracting solution,
Crocus sativus and hyaluronic acid, can supplement eye part skin nutrition and moisture rapidly, recover the elasticity of eye part skin, together
When, also contain palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5 in the eye cream liquid, it can be with restoring ocular skin
Damage, eye wrinkle-removing is dispelled, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to improve eye
The immunity of portion's skin, strengthens tolerance and resistance of the skin to external environment, is really achieved the effect of eye skin rejuvenation
Fruit, so as to resist the generation of eye wrinkle-removing, delays the aging of eye skin.
The invention is further illustrated by the following examples, but the embodiment is merely to illustrate the present invention rather than limitation
The present invention.
Formula as described in table 1 prepares eye cream, then carries out using effect test and carries out effect statistics.
Table 1
The method of using effect test：
60 female volunteers are selected, age distribution is 16-40 Sui, is randomly divided into six groups, every group 10 of A, B, C, D, E, F
People.The eye cream that wherein application of A groups is prepared by formula 1 in the above-mentioned table 1 of the present invention, the application of B groups in the above-mentioned table 1 of the present invention by being formulated 2
The eye cream of preparation, the eye cream that the application of C groups is prepared by formula 3 in the above-mentioned table 1 of the present invention, the application of D groups in the above-mentioned table 1 of the present invention by matching somebody with somebody
Eye cream prepared by side 4, the eye cream that the application of E groups is prepared by formula 5 in the above-mentioned table 1 of the present invention, the eye cream of F groups application routine, respectively
Eye part skin wrinkle condition is detected after 4 weeks in continuous use, and is thus disabled eye cream product and eye part skin situation is detected after 8 weeks existed
Testing result is shown in Table 2.
Table 2
| A groups | After 4 weeks, eye wrinkle-removing is reduced；Eye wrinkle-removing is without increase after disabling 8 weeks. |
| B groups | After 4 weeks, eye wrinkle-removing is reduced；Eye wrinkle-removing is without increase after disabling 8 weeks. |
| C groups | After 4 weeks, eye wrinkle-removing is reduced；Eye wrinkle-removing is without increase after disabling 8 weeks. |
| D groups | After 4 weeks, eye wrinkle-removing is reduced；Eye wrinkle-removing is without increase after disabling 8 weeks. |
| E groups | After 4 weeks, eye wrinkle-removing is reduced；Eye wrinkle-removing is without increase after disabling 8 weeks. |
| F groups | After 4 weeks, eye wrinkle-removing is somewhat reduced；Eye wrinkle-removing increase is obvious after disabling 8 weeks. |
Can be seen that the eye cream provided by the invention containing stem cell secretion factor from the using effect in upper table can repair
The damage of eye skin, dispels eye wrinkle-removing, but also can resist the generation of eye wrinkle-removing, so as to really slow down aging.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not
In the case of departing from the principle of the present invention and objective a variety of change, modification, replacement and modification can be carried out to these embodiments, this
The scope of invention is limited by claim and its equivalent.
Claims (9)
1. a kind of eye cream containing stem cell secretion factor, it is characterised in that the eye cream includes palmityl tetrapeptide -7, palmityl three
Peptide -5, acetyl group tetrapeptide -5, stem cell secretion factor, adlay extracting solution, red bean extracting solution, crocus sativus, hyaluronic acid
And deionized water.
2. eye cream as claimed in claim 1, it is characterised in that based on 100 parts by weight, the eye cream includes following components：
0.5-1.5 parts of palmityl tetrapeptide -7,0.6-1.0 part palmityl tripeptides -5,1.0-1.5 part acetyl group tetrapeptides -5,0.2-0.5 part are dry
Cell-secretion factor, 2-4 parts of adlay extracting solutions, 3-5 parts of red bean extracting solutions, 2.5-3.0 parts of crocus sativus, 0.5-1.0 parts
Hyaluronic acid and deionized water surplus.
3. eye cream as claimed in claim 2, it is characterised in that based on 100 parts by weight, the eye cream includes following components：
0.8-1.2 parts of palmityl tetrapeptide -7,0.7-0.8 part palmityl tripeptides -5,1.2-1.4 part acetyl group tetrapeptides -5,0.3-0.4 part are dry
Cell-secretion factor, 2.5-3.5 parts of adlay extracting solutions, 3.5-4.5 parts of red bean extracting solutions, 2.6-2.8 parts of crocus sativus,
0.6-0.8 parts of hyaluronic acids and deionized water surplus.
4. eye cream as claimed in claim 1, it is characterised in that the eye cream further includes emulsifying agent, the emulsifying agent be selected from
In glyceryl monostearate, cetostearyl alcohol, C9-15 alcohol phosphate, laruyl alcohol phosphate and C20-22 alcohol phosphates at least
It is a kind of.
5. eye cream as claimed in claim 4, it is characterised in that in terms of 100 parts by weight, the content of the emulsifying agent is 4-8 parts.
6. eye cream as claimed in claim 1, it is characterised in that the eye cream is further included in vitamin A and vitamin E at least
It is a kind of.
7. eye cream as claimed in claim 6, it is characterised in that in terms of 100 parts by weight, the content of the vitamin A is 0.5-
1.5 parts, the content of the vitamin E is 0.5-1.5 parts.
8. eye cream as claimed in claim 1, it is characterised in that in terms of 100 parts by weight, the eye cream further includes 0.5-2.5 parts
Antiseptic.
9. eye cream as claimed in claim 8, it is characterised in that the antiseptic is pressed for potassium sorbate or pungent glycol with pentanediol
1:2-1:The Compositional antiseptic agent of 5 compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711297993.3A CN107961198A (en) | 2017-12-08 | 2017-12-08 | Eye cream containing stem cell secretory factors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711297993.3A CN107961198A (en) | 2017-12-08 | 2017-12-08 | Eye cream containing stem cell secretory factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107961198A true CN107961198A (en) | 2018-04-27 |
Family
ID=61998374
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711297993.3A Withdrawn CN107961198A (en) | 2017-12-08 | 2017-12-08 | Eye cream containing stem cell secretory factors |
Country Status (1)
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110464685A (en) * | 2019-09-11 | 2019-11-19 | 天津天之禹化妆品有限公司 | A kind of agalloch eaglewood tax eye cream living containing the cell repair factor |
| CN111035609A (en) * | 2020-01-10 | 2020-04-21 | 上海赵小蝶化妆品有限公司 | Micromolecular polypeptide eye essence and preparation method thereof |
| CN113786376A (en) * | 2021-09-26 | 2021-12-14 | 湖北省麦诗特生物科技有限公司 | Eye cream composition with eyeprint removing effect and preparation method thereof |
| CN114028259A (en) * | 2020-08-11 | 2022-02-11 | 广东长昊药业股份有限公司 | Eye cream and preparation method thereof |
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| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
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| 王建新 等: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110464685A (en) * | 2019-09-11 | 2019-11-19 | 天津天之禹化妆品有限公司 | A kind of agalloch eaglewood tax eye cream living containing the cell repair factor |
| CN111035609A (en) * | 2020-01-10 | 2020-04-21 | 上海赵小蝶化妆品有限公司 | Micromolecular polypeptide eye essence and preparation method thereof |
| CN114028259A (en) * | 2020-08-11 | 2022-02-11 | 广东长昊药业股份有限公司 | Eye cream and preparation method thereof |
| CN113786376A (en) * | 2021-09-26 | 2021-12-14 | 湖北省麦诗特生物科技有限公司 | Eye cream composition with eyeprint removing effect and preparation method thereof |
| CN113786376B (en) * | 2021-09-26 | 2024-02-23 | 湖北省麦诗特生物科技有限公司 | Eye cream composition with eye pattern removing effect and preparation method thereof |
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