CN107982097A - Face cream containing stem cell secretion factors - Google Patents
Face cream containing stem cell secretion factors Download PDFInfo
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- CN107982097A CN107982097A CN201711297994.8A CN201711297994A CN107982097A CN 107982097 A CN107982097 A CN 107982097A CN 201711297994 A CN201711297994 A CN 201711297994A CN 107982097 A CN107982097 A CN 107982097A
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- face cream
- skin
- face
- stem cell
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a cream containing stem cell secretion factors, which comprises palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, acetyl tetrapeptide-5, stem cell secretion factors, silicone oil, jojoba seed oil, a plant extract, an emulsifier, a thickener and deionized water. According to the facial cream disclosed by the invention, the facial cream can repair skin injury, remove wrinkles, improve the immunity of facial skin, enhance the tolerance and resistance of the skin to the external environment, and really achieve the effect of facial skin rejuvenation, so that the facial wrinkles are resisted.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly, to a kind of face cream containing stem cell secretion factor.
Background technology
Skin of face is often subject to environmental stimuli and infringement, is very easy to cause skin injury, makes skin outside being chronically exposed to
Skin becomes dry, follows the string, and as the increase at age, facial wrinkles gradually show, this is for the women that likes to be beautiful
It is intolerable, therefore facial-care is even more important for women.
Existing facial-care product, normally only has certain moist moisturizing effect, is only capable of temporarily alleviating skin and lacks
, there are some facial-care face creams in the problem of water and claim with anti-aging on the market, but it improves wrinkle, work(of microgroove
Imitate relatively poor.Moreover, existing face cream on the market is generally the defensive face cream of physics, it is only capable of forming one on face skin surface
Layer physical protection film, to resist environmental nuisance, it can not fundamentally improve the resistance of skin of face, to reach resistance face
The effect that wrinkle is produced, really slowed down aging.
The content of the invention
In view of this, it is an object of the invention to provide a kind of face cream containing stem cell secretion factor, the face cream to repair
Face skin damages, while improving facial wrinkles, moreover it is possible to improves the immunity of face skin cell, and then resists facial wrinkles
Generation, fundamentally slow down aging.
To achieve the above object, the present invention provides a kind of face cream containing stem cell secretion factor, including palmityl tetrapeptide-
7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, silicone oil, jojoba seed oil, plant extracts, emulsifying agent,
Thickener and deionized water.
Preferably, based on 100 parts by weight, the face cream includes following components：1.0-1.5 parts of palmityl tetrapeptides -7,0.8-
2.0 parts of palmityl tripeptides -5,1.0-2.5 part acetyl group tetrapeptide -5,0.5-1.0 part stem cell secretion factors, 3-6 parts of silicone oil, 4-8
Part jojoba seed oil, 5-10 parts of plant extracts, 5-10 parts of emulsifying agents, 5-10 parts of thickeners and deionized water surplus.
Preferably, based on 100 parts by weight, the face cream includes following components：1.2-1.4 parts of palmityl tetrapeptides -7,1.0-
1.8 parts of palmityl tripeptides -5,1.5-2.0 part acetyl group tetrapeptide -5,0.6-0.8 part stem cell secretion factors, 4-5 parts of silicone oil, 5-7
Part jojoba seed oil, 6-8 parts of plant extracts, 6-8 parts of emulsifying agents, 6-9 parts of thickeners and deionized water surplus.
Preferably, the emulsifying agent is at least one in arachidic alcohol, cetostearyl alcohol, beeswax and laruyl alcohol phosphate
Kind.
Preferably, the thickener is at least one in carboxymethyl cellulose, sodium alginate, and polyethylene glycol
Kind.
Preferably, the plant extracts is one kind in adlay extract, Semen Ormosiae Semicastratae extract, safranine flower extract
It is or a variety of.
Preferably, in terms of 100 parts by weight, the face cream further includes 1.5-2.5 parts of hydrolytic collagens.
The face cream containing stem cell secretion factor provided according to the present invention, wherein contain silicone oil, jojoba seed oil and plant
Thing extract, can supplement skin of face nutrition and moisture rapidly, recover the elasticity of skin of face, meanwhile, in the face cream liquid also
Containing palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5, it can repair the damage of face skin, dispel face
Wrinkle, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to the immunity of skin of face is improved,
Strengthen skin to the tolerance and resistance of external environment, the effect of face skin rejuvenation is really achieved, so as to resist face
The generation of wrinkle, delays the aging of face skin.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obtain substantially, or recognized by the practice of the present invention.
Embodiment
In order to better illustrate the present invention, with reference to specific embodiment, the present invention will be further described.It is appreciated that
, these specific embodiments are exemplary, are only used for explaining the present invention, and are not considered as limiting the invention.
The embodiment of the present invention provides a kind of face cream containing stem cell secretion factor, which includes palmityl tetrapeptide -7,
Palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, silicone oil, jojoba seed oil, plant extracts, emulsifying agent, increases
Thick dose and deionized water.
Palmityl tetrapeptide -7 be it is a kind of victory peptide is synthesized by four Amino acid profiles, can delay and to suppress excessive cell white
The generation of interleukin, so as to suppress some unnecessary inappropriate inflammatory reactions and glycosylation damage, has and significantly smoothes away wrinkles
Effect, tolerance of the skin to external environment can be strengthened.Meanwhile it can also stimulate collagen (I in dermal layer of the skin
Type, II type, IV type) and elastin laminin synthesis and development, reach the effect of compacting with plentiful skin.Palmityl tripeptides -5 can be with
Promote the life of the synthesis of collagen (I type, II type familial combined hyperlipidemia) and extracellular matrix protein by increasing stroma cell activity
Into, strengthen connective tissue, promote cytoactive, while protect collagen not decomposed by matrix metalloproteinase, both cooperate with
Effect, effective wrinkle reduction, improves skin quality, allows skin to seem more aobvious young and high resilience.Make collagen used in saccharification
Be cross-linked with each other, its be produce wrinkle the reason for one of, acetyl tetrapeptide -5 can suppress saccharification, so as to reduce collagen
It is cross-linked with each other, reaches the effect of mitigating wrinkle and resistance wrinkle, improves the elasticity and smoothness of skin.
Stem cell secretion factor contains the extremely strong growth factor of a large amount of physiological actions, can activate in vivo in a dormant state
Various stem cells, supplement various fresh cells for body, substitute aging and impaired volume cell, and then repair skin damage
Wound, wrinkle reduction, makes skin reach the state of overall rejuvenation.Meanwhile stem cell secretion factor is also containing being improved immunity
The factor, can stimulate leucocyte to regenerate, and improve cutaneous immunisation power, and then improve tolerance and resistance of the skin to adverse circumstances
Power, is significantly reduced the generation of skin problem.
It is understood that palmityl tetrapeptide -7 in the present invention, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell
Secretion factor can be prepared using method commonly used in the art, this is not described in detail in the present invention.
Silicone oil has relatively low surface tension, and the good lubrication of skin is acted on, can form one layer of waterproof on the skin
The film of property, and without greasy feeling, antistatic, be not afraid of ultraviolet, do not influence to perspire, can permanent moisturizing, and then contribute to other
The absorption of active ingredient.Jojoba seed oil has good permeability, is to moisten well containing abundant vitamin D and protein
And moisturizing oil, it can safeguard moisture of skin, pre- anti-wrinkle and softening skin, be adapted to ripe and aging skin.
In some embodiments of the invention, based on 100 parts by weight, based on 100 parts by weight, the face cream is included with the following group
Point：1.0-1.5 parts of palmityl tetrapeptide -7,0.8-2.0 part palmityl tripeptides -5,1.0-2.5 part acetyl group tetrapeptides -5,0.5-1.0
Part stem cell secretion factor, 3-6 parts of silicone oil, 4-8 parts of jojoba seed oils, 5-10 parts of plant extracts, 5-10 parts of emulsifying agents, 5-10
Part thickener and deionized water surplus.Preferably, in other embodiments of the present invention, based on 100 parts by weight, the face
Frost includes following components：1.2-1.4 parts of palmityl tetrapeptide -7,1.0-1.8 part palmityl tripeptides -5,1.5-2.0 part acetyl group four
Peptide -5,0.6-0.8 part stem cell secretion factor, 4-5 parts of silicone oil, 5-7 parts of jojoba seed oils, 6-8 parts of plant extracts, 6-8 parts
Emulsifying agent, 6-9 parts of thickeners and deionized water surplus.
It is understood that the present invention is not particularly limited the species of plant extracts, it can be various this areas
Common plant extracts, as long as skin-nourishing can be supplemented.In some embodiments of the invention, the plant extracts
For selected from adlay extract, Semen Ormosiae Semicastratae extract, the one or more in safranine flower extract.
Adlay extract, which has, controls the flat acne of wart, light speckles, beautification and white, moisturizing smoothing wrinkle and other effects, especially contained breaks down proteins
Ferment can soften skin keratin, vitamin E Wheat Protein；Semen Ormosiae Semicastratae extract has the health-care effects such as detumescence；Safflower
The main component of extract is crocetin and crocin, it has effects that to increase skin elasticity, crease-resistant.Hyaluronic acid energy
The loss of hyaluronic acid, increases the collagen and elastomer in corium, eliminates cutis laxa, subtract in enough rapid supplement skin
The wrinkle of few face.It can also be appreciated that the adlay extract in the present invention, Semen Ormosiae Semicastratae extract, safranine flower extract with
And the material such as hyaluronic acid can be prepared using method commonly used in the art, this is not described in detail in the present invention.
It is understood that the present invention is not particularly limited the species of emulsifying agent, it can be breast commonly used in the art
Agent, for example, in some embodiments of the invention, the emulsifying agent is selected from arachidic alcohol, cetostearyl alcohol, beeswax and bay
At least one of alcohol phosphate.
Thickener can improve the mobility, dispersiveness and permeability of face cream, so as to promote the percutaneous suction of face cream component
Yield.It is understood that the present invention is not particularly limited the species of thickener, can be various thickenings commonly used in the art
Agent, for example, in some embodiments of the invention, the thickener is selected from carboxymethyl cellulose, sodium alginate, and poly- second two
At least one of alcohol.
Hydrolytic collagen can also be added in the face cream of the present invention.Hydrolytic collagen can easily be absorbed by the body, rapid supplement
The Collagen material being lost in is organized, and then recovers skin elasticity.It is described in some embodiments of the invention in terms of 100 parts by weight
The content of hydrolytic collagen is 1.5-2.5 parts.
The face cream containing stem cell secretion factor provided according to the present invention, can use this area routine method preparation and
, the application no longer repeats this.
The face cream containing stem cell secretion factor provided according to the present invention, wherein contain silicone oil, jojoba seed oil and plant
Thing extract, can supplement skin of face nutrition and moisture rapidly, recover the elasticity of skin of face, meanwhile, in the face cream liquid also
Containing palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5, it can repair the damage of face skin, dispel face
Wrinkle, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to the immunity of skin of face is improved,
Strengthen skin to the tolerance and resistance of external environment, the effect of face skin rejuvenation is really achieved, so as to resist face
The generation of wrinkle, delays the aging of face skin.
The invention is further illustrated by the following examples, but the embodiment is merely to illustrate the present invention rather than limitation
The present invention.
Formula as described in table 1 prepares face cream, then carries out using effect test and carries out effect statistics.
Table 1
The method of using effect test：
60 female volunteers are selected, age distribution is 16-40 Sui, is randomly divided into six groups, every group 10 of A, B, C, D, E, F
People.The face cream that wherein application of A groups is prepared by formula 1 in the above-mentioned table 1 of the present invention, the application of B groups in the above-mentioned table 1 of the present invention by being formulated 2
The face cream of preparation, the face cream that the application of C groups is prepared by formula 3 in the above-mentioned table 1 of the present invention, the application of D groups in the above-mentioned table 1 of the present invention by matching somebody with somebody
Face cream prepared by side 4, the face cream that the application of E groups is prepared by formula 5 in the above-mentioned table 1 of the present invention, the face cream of F groups application routine, respectively
Continuous use 4 weeks after detect face skin wrinkle situation, and thus disable face cream product detect after 8 weeks face skin exist
Testing result is shown in Table 2.
Table 2
| A groups | After 4 weeks, facial wrinkles are reduced；8 weeks rear face wrinkles are disabled without increase. |
| B groups | After 4 weeks, facial wrinkles are reduced；8 weeks rear face wrinkles are disabled without increase. |
| C groups | After 4 weeks, facial wrinkles are reduced；8 weeks rear face wrinkles are disabled without increase. |
| D groups | After 4 weeks, facial wrinkles are reduced；8 weeks rear face wrinkles are disabled without increase. |
| E groups | After 4 weeks, facial wrinkles are reduced；8 weeks rear face wrinkles are disabled without increase. |
| F groups | After 4 weeks, facial wrinkles are somewhat reduced；It is more apparent to disable rear face wrinkle increase in 8 weeks. |
Can be seen that the face cream provided by the invention containing stem cell secretion factor from the using effect in upper table can repair
The damage of face skin, dispels facial wrinkles, but also can resist the generation of facial wrinkles, so as to really slow down aging.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not
In the case of departing from the principle of the present invention and objective a variety of change, modification, replacement and modification can be carried out to these embodiments, this
The scope of invention is limited by claim and its equivalent.
Claims (7)
1. a kind of face cream containing stem cell secretion factor, it is characterised in that the face cream includes palmityl tetrapeptide -7, palmityl three
Peptide -5, acetyl group tetrapeptide -5, stem cell secretion factor, silicone oil, jojoba seed oil, plant extracts, emulsifying agent, thickener and
Deionized water.
2. face cream as claimed in claim 1, it is characterised in that based on 100 parts by weight, the face cream includes following components：
1.0-1.5 parts of palmityl tetrapeptide -7,0.8-2.0 part palmityl tripeptides -5,1.0-2.5 part acetyl group tetrapeptides -5,0.5-1.0 part are dry
Cell-secretion factor, 3-6 parts of silicone oil, 4-8 parts of jojoba seed oils, 5-10 parts of plant extracts, 5-10 parts of emulsifying agents, 5-10 parts of increasings
Thick dose and deionized water surplus.
3. face cream as claimed in claim 2, it is characterised in that based on 100 parts by weight, the face cream includes following components：
1.2-1.4 parts of palmityl tetrapeptide -7,1.0-1.8 part palmityl tripeptides -5,1.5-2.0 part acetyl group tetrapeptides -5,0.6-0.8 part are dry
Cell-secretion factor, 4-5 parts of silicone oil, 5-7 parts of jojoba seed oils, 6-8 parts of plant extracts, 6-8 parts of emulsifying agents, 6-9 parts of thickenings
Agent and deionized water surplus.
4. face cream as claimed in claim 1, it is characterised in that the emulsifying agent is selected from arachidic alcohol, cetostearyl alcohol, beeswax
And at least one of laruyl alcohol phosphate.
5. face cream as claimed in claim 1, it is characterised in that the thickener is the sodium alginate selected from carboxymethyl cellulose,
And at least one of polyethylene glycol.
6. face cream as claimed in claim 1, it is characterised in that the plant extracts is to be carried selected from adlay extract, red bean
Take thing, the one or more in safranine flower extract.
7. face cream as claimed in claim 1, it is characterised in that in terms of 100 parts by weight, the face cream further includes 1.5-2.5 parts
Hydrolytic collagen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711297994.8A CN107982097A (en) | 2017-12-08 | 2017-12-08 | Face cream containing stem cell secretion factors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711297994.8A CN107982097A (en) | 2017-12-08 | 2017-12-08 | Face cream containing stem cell secretion factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107982097A true CN107982097A (en) | 2018-05-04 |
Family
ID=62037079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711297994.8A Withdrawn CN107982097A (en) | 2017-12-08 | 2017-12-08 | Face cream containing stem cell secretion factors |
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| Country | Link |
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| CN (1) | CN107982097A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125107A (en) * | 2018-09-20 | 2019-01-04 | 深圳市维琪医药研发有限公司 | A kind of peptide composition being effectively improved and repair therapy of facial hormone dependent dermatitis |
| CN112675063A (en) * | 2020-12-30 | 2021-04-20 | 王超云 | Skin-tendering anti-wrinkle composition containing PDRN and application thereof |
| CN113786376A (en) * | 2021-09-26 | 2021-12-14 | 湖北省麦诗特生物科技有限公司 | Eye cream composition with eyeprint removing effect and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
-
2017
- 2017-12-08 CN CN201711297994.8A patent/CN107982097A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
Non-Patent Citations (1)
| Title |
|---|
| 钟星等: "胜肽在化妆品中的应用和最新进展", 《日用化学品科学》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125107A (en) * | 2018-09-20 | 2019-01-04 | 深圳市维琪医药研发有限公司 | A kind of peptide composition being effectively improved and repair therapy of facial hormone dependent dermatitis |
| CN112675063A (en) * | 2020-12-30 | 2021-04-20 | 王超云 | Skin-tendering anti-wrinkle composition containing PDRN and application thereof |
| CN113786376A (en) * | 2021-09-26 | 2021-12-14 | 湖北省麦诗特生物科技有限公司 | Eye cream composition with eyeprint removing effect and preparation method thereof |
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Application publication date: 20180504 |