CN107898657A - Eye mask containing stem cell secretion factors - Google Patents

Eye mask containing stem cell secretion factors Download PDF

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Publication number
CN107898657A
CN107898657A CN201711296320.6A CN201711296320A CN107898657A CN 107898657 A CN107898657 A CN 107898657A CN 201711296320 A CN201711296320 A CN 201711296320A CN 107898657 A CN107898657 A CN 107898657A
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CN
China
Prior art keywords
eye mask
eye
parts
skin
stem cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201711296320.6A
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Chinese (zh)
Inventor
陈海佳
葛啸虎
王飞
王一飞
王小燕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Saliai StemCell Science and Technology Co Ltd
Original Assignee
Guangzhou Saliai StemCell Science and Technology Co Ltd
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Filing date
Publication date
Application filed by Guangzhou Saliai StemCell Science and Technology Co Ltd filed Critical Guangzhou Saliai StemCell Science and Technology Co Ltd
Priority to CN201711296320.6A priority Critical patent/CN107898657A/en
Publication of CN107898657A publication Critical patent/CN107898657A/en
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses an eye mask containing stem cell secretion factors, which comprises eye mask base cloth and eye mask liquid, wherein the eye mask liquid comprises palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, acetyl tetrapeptide-5, stem cell secretion factors, a humectant, hyaluronic acid and deionized water. The eye mask disclosed by the invention can repair skin injury, dispel eye wrinkles, improve the immunity of eye skin, enhance the tolerance and resistance of skin to the external environment, and really achieve the effect of rejuvenating the eye skin, so that the eye wrinkles are resisted.

Description

A kind of eye mask containing stem cell secretion factor
Technical field
The present invention relates to cosmetic technical field, more particularly, to a kind of eye mask containing stem cell secretion factor.
Background technology
Eye skin is the most thin skin of human body, while is the most frequent position of activity again, and modern often stays up late, during rest Between deficiency, be very easy to cause eyes muscular fatigue;And with advancing age, face skin, orbital septum aponeurosis, orbicular muscle of eye under eyes It is loose that degeneration change can be produced, fold occur, the generation of eye microgroove means the exposure at age, therefore eye-care for It is even more important for women.
Existing eyeware products and solution for lenses and contact lenses, normally only has effects that to moisten or mitigate the symptoms such as livid ring around eye, pouch, it improves The effect of wrinkle, microgroove, is relatively poor.Even if some products can repair skin injury to a certain extent, dispel eye wrinkle Line, but these products be only conceived to eye part skin problem occur after how to solve or repair, its while alleviation or reparation, The resistance of eye part skin can not be fundamentally improved, to reach the generation of resistance eye wrinkle-removing.
The content of the invention
In view of this, it is an object of the invention to provide a kind of eye mask containing stem cell secretion factor, the eye mask to repair Eye skin is damaged, while dispelling eye wrinkle-removing, moreover it is possible to improve the immunity of eye skin cell, resist the production of eye wrinkle-removing It is raw.
To achieve the above object, the present invention provides a kind of eye mask containing stem cell secretion factor, the eye mask to include eye mask Base fabric and eye mask liquid, the eye mask liquid include palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion The factor, moisturizer, hyaluronic acid and deionized water.
Preferably, based on 100 parts by weight, the eye mask liquid includes following components:0.4-1 parts of palmityl tetrapeptides -7,0.3- 0.8 part of palmityl tripeptides -5,0.8-1.2 part acetyl group tetrapeptide -5,0.5-0.8 part stem cell secretion factor, 6-9 parts of moisturizer, 0.5-1.0 parts of hyaluronic acids and deionized water surplus.
Preferably, based on 100 parts by weight, the eye mask liquid includes following components:0.5-0.8 parts of palmityl tetrapeptide -7, 0.4-0.6 parts of palmityl tripeptides -5,0.9-1.0 part acetyl group tetrapeptide -5,0.6-0.8 part stem cell secretion factors, 7-8 parts of moisturizings Agent, 0.6-0.8 parts of hyaluronic acids and deionized water surplus.
Preferably, the moisturizer is the one or more in glycerine, Sodium Hyaluronate and butanediol.
Preferably, the eye mask liquid further includes water-soluble thickener, and based on 100 parts by weight, the eye mask liquid includes 6-8 parts Thickener.
Preferably, the thickener is in xanthans, hydroxyethyl cellulose, carbomer, mosanom and Sodium Hyaluronate It is at least one.
Preferably, the eye mask base fabric is by keratin fiber, cotton fiber, wood fibre, bamboo charcoal fiber, silk, chitosan One or more kinds of materials in fiber and alginate fibre are made.
The eye mask containing stem cell secretion factor provided according to the present invention, contains moisturizer and hyalomitome in its eye mask liquid Acid, can supplement eye part skin moisture rapidly, recover the elasticity of eye part skin, meanwhile, palmityl four is also contained in the eye mask liquid Peptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5, it can be dispelled eye wrinkle-removing, matched somebody with somebody at the same time with the damage of restoring ocular skin Stem cell secretion factor is closed, while skin injury is repaired, additionally it is possible to improve the immunity of eye part skin, enhancing skin is external The tolerance and resistance of boundary's environment, are really achieved the effect of eye skin rejuvenation, so as to resist the generation of eye wrinkle-removing.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description Obtain substantially, or recognized by the practice of the present invention.
Embodiment
In order to better illustrate the present invention, with reference to specific embodiment, the present invention will be further described.It is appreciated that , these specific embodiments are exemplary, are only used for explaining the present invention, and are not considered as limiting the invention.
The embodiment of the present invention provides a kind of eye mask containing stem cell secretion factor, which includes eye mask base fabric and eye mask Liquid, the eye mask liquid include palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, moisturizing Agent, hyaluronic acid and deionized water.
Palmityl tetrapeptide -7 be it is a kind of victory peptide is synthesized by four Amino acid profiles, can delay and to suppress excessive cell white The generation of interleukin, so as to suppress some unnecessary inappropriate inflammatory reactions and glycosylation damage, there is significant anti-eyelid to float Effect that is swollen, eliminating pouch, anti-inflammatory, can strengthen tolerance of the skin to external environment.Meanwhile it can also stimulate skin The synthesis and development of collagen (I types, II type, IV type) and elastin laminin, reach the work(to compact with plentiful skin in skin corium Effect.Palmityl tripeptides -5 can by increase stroma cell activity promote the synthesis of collagen (I types, II type familial combined hyperlipidemia) and The generation of extracellular matrix protein, strengthens connective tissue, promotes cytoactive, while protect collagen not by matrix metal egg White enzyme decomposes, both act synergistically, effective wrinkle reduction, improves skin quality, allows skin to seem more aobvious young and high resilience.Sugar Collagen is cross-linked with each other used in change, its be produce pouch the reason for one of, acetyl tetrapeptide -5 can suppress saccharification, from And being cross-linked with each other for collagen is reduced, reach the effect of mitigating pouch and resistance wrinkle, improve the elasticity and smoothness of skin.
Stem cell secretion factor contains the extremely strong growth factor of a large amount of physiological actions, can activate in vivo in a dormant state Various stem cells, supplement various fresh cells for body, substitute aging and impaired volume cell, and then repair skin damage Wound, wrinkle reduction, makes skin reach the state of overall rejuvenation.Meanwhile stem cell secretion factor is also containing being improved immunity The factor, can stimulate leucocyte to regenerate, and improve cutaneous immunisation power, and then improve tolerance and resistance of the skin to adverse circumstances Power, is significantly reduced the generation of skin problem.
It is understood that palmityl tetrapeptide -7 in the present invention, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell Secretion factor can be prepared using method commonly used in the art, this is not described in detail in the present invention.
Moisturizer is added in eye mask can ensure that eye mask has good moistening effect, it is to be understood that the present invention Moisturizer commonly used in the art can be provided in the eye mask of offer.Preferably, in some embodiments of the invention, the moisturizing Agent is the one or more in glycerine, Sodium Hyaluronate and butanediol.Glycerine can give the cuticula supplement water of eye skin Point, adjust skin sense;Sodium Hyaluronate penetrates readily through skin, is deep to reach into skin corium and is combined with water, while keeping moisture of skin Moisture in absorbable air, the effect of playing dual moisturizing water lock, it can also improve the microcirculation and nutrition of local skin Absorb, promote the regeneration of eye part skin cell, Firm is crease-resistant;Butanediol is small molecule moisturizing composition, has moisture-keeping function, at the same time Also there is certain bacteriostasis.
In some embodiments of the invention, the eye mask liquid further includes water-soluble thickener, i.e. the water-soluble thickener It is water miscible or the polymer being dispersed in water can be mixed with water, it can improves the viscosity of eye mask liquid, so as to make eye Film liquid can be preferably attracted in eye mask base fabric, meanwhile, water-soluble thickener can also improve the mobility of eye mask liquid, disperse Property and permeability, so as to promote the percutaneous absorbtion of eye mask liquid, promote skin metabolism and microcirculation.
In some embodiments of the invention, based on 100 parts by weight, the eye mask liquid includes 6-8 parts of thickeners.It can manage Solve, the water-soluble thickener in the present invention can use water-soluble thickener commonly used in the art, and the present invention is not special Limitation.Preferably, in some embodiments of the invention, the water-soluble thickener is xanthans, hydroxyethyl cellulose, card ripple At least one of nurse, mosanom and Sodium Hyaluronate.
Eye mask provided by the invention includes eye mask base fabric, and eye mask base fabric is as medium, and for adsorbing eye mask liquid, it is being used When, eye specific location can be fixed on, forms confining bed, promotes the absorption of eye mask liquid.Eye mask base fabric is to eye mask liquid The factors such as the affinity of adsorption capacity, gas permeability and skin have material impact to the use feeling and effect of eye mask.It is appreciated that , of the invention that eye mask base fabric is not particularly limited, it can be eye mask base fabric commonly used in the art.Preferably, in this hair In some bright embodiments, the eye mask base fabric is gathered by keratin fiber, cotton fiber, wood fibre, bamboo charcoal fiber, silk, shell One or more kinds of materials in sugared fiber and alginate fibre are made.
In some embodiments of the invention, based on 100 parts by weight, the eye mask liquid includes following components:0.4-1 parts of palm fibres Palmitic acid acyl tetrapeptide -7,0.3-0.8 part palmityl tripeptides -5,0.8-1.2 part acetyl group tetrapeptide -5,0.5-0.8 part stem cell secretion because Son, 6-9 parts of moisturizer, 0.5-1.0 parts of hyaluronic acids and deionized water surplus.Preferably, in other implementations of the present invention In example, based on 100 parts by weight, the eye mask liquid includes following components:0.5-0.8 parts of palmityl tetrapeptide -7,0.4-0.6 part palms Acyl tripeptides -5,0.9-1.0 part acetyl group tetrapeptide -5,0.6-0.8 part stem cell secretion factor, 7-8 parts of moisturizer, 0.6-0.8 parts Hyaluronic acid and deionized water surplus.
The eye mask containing stem cell secretion factor provided according to the present invention, can use this area routine method preparation and , the application no longer repeats this.
The eye mask containing stem cell secretion factor provided according to the present invention, contains moisturizer and hyalomitome in its eye mask liquid Acid, can supplement eye part skin moisture rapidly, recover the elasticity of eye part skin, meanwhile, palmityl four is also contained in the eye mask liquid Peptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5, it can be dispelled eye wrinkle-removing, matched somebody with somebody at the same time with the damage of restoring ocular skin Stem cell secretion factor is closed, while skin injury is repaired, additionally it is possible to improve the immunity of eye part skin, enhancing skin is external The tolerance and resistance of boundary's environment, are really achieved the effect of eye skin rejuvenation, so as to resist the generation of eye wrinkle-removing.
The invention is further illustrated by the following examples, but the embodiment is merely to illustrate the present invention rather than limitation The present invention.
Formula as described in table 1 prepares eye mask, carries out using effect test and carries out effect statistics.
Table 1
The method of using effect test:
60 female volunteers are selected, age distribution is 16-40 Sui, is randomly divided into six groups, every group 10 of A, B, C, D, E, F People.The eye mask that wherein application of A groups is prepared by formula 1 in the above-mentioned table 1 of the present invention, the application of B groups in the above-mentioned table 1 of the present invention by being formulated 2 The eye mask of preparation, the eye mask that the application of C groups is prepared by formula 3 in the above-mentioned table 1 of the present invention, the application of D groups in the above-mentioned table 1 of the present invention by matching somebody with somebody Eye mask prepared by side 4, the eye mask that the application of E groups is prepared by formula 5 in the above-mentioned table 1 of the present invention, the eye mask of F groups application routine, respectively Eye part skin situation is detected after 6 weeks in continuous use, and is thus disabled eye mask product and eye part skin situation is detected after 4 weeks detected It the results are shown in Table 2.
Table 2
Can be seen that the eye mask provided by the invention containing stem cell secretion factor from the using effect in upper table can repair The damage of eye skin, dispels eye wrinkle-removing, but also can resist the generation of eye wrinkle-removing, so as to really slow down aging.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that:Not In the case of departing from the principle of the present invention and objective a variety of change, modification, replacement and modification can be carried out to these embodiments, this The scope of invention is limited by claim and its equivalent.

Claims (7)

1. a kind of eye mask containing stem cell secretion factor, it is characterised in that the eye mask includes eye mask base fabric and eye mask liquid, described Eye mask liquid includes palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, moisturizer, hyalomitome Acid and deionized water.
2. eye mask as claimed in claim 1, it is characterised in that based on 100 parts by weight, the eye mask liquid includes following components: 0.4-1 parts of palmityl tetrapeptide -7,0.3-0.8 part palmityl tripeptides -5,0.8-1.2 part acetyl group tetrapeptides -5,0.5-0.8 part are dry thin The intracrine factor, 6-9 parts of moisturizer, 0.5-1.0 parts of hyaluronic acids and deionized water surplus.
3. eye mask as claimed in claim 2, it is characterised in that based on 100 parts by weight, the eye mask liquid includes following components: 0.5-0.8 parts of palmityl tetrapeptide -7,0.4-0.6 part palmityl tripeptides -5,0.9-1.0 part acetyl group tetrapeptides -5,0.6-0.8 part are dry Cell-secretion factor, 7-8 parts of moisturizer, 0.6-0.8 parts of hyaluronic acids and deionized water surplus.
4. eye mask as claimed in claim 1, it is characterised in that the moisturizer is selected from glycerine, Sodium Hyaluronate and fourth two One or more in alcohol.
5. eye mask as claimed in claim 1, it is characterised in that the eye mask liquid further includes water-soluble thickener, by 100 weight Part meter, the eye mask liquid include 6-8 parts of thickeners.
6. eye mask as claimed in claim 4, it is characterised in that the water-soluble thickener for xanthans, hydroxyethyl cellulose, At least one of carbomer, mosanom and Sodium Hyaluronate.
7. eye mask as claimed in claim 1, it is characterised in that the eye mask base fabric is by keratin fiber, cotton fiber, wooden fibre One or more kinds of materials in dimension, bamboo charcoal fiber, silk, chitin fiber and alginate fibre are made.
CN201711296320.6A 2017-12-08 2017-12-08 Eye mask containing stem cell secretion factors Withdrawn CN107898657A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108714123A (en) * 2018-06-15 2018-10-30 广州无添加主义化妆品有限公司 A kind of multiple-effect eye mask liquid, eye mask and preparation method thereof
CN109998939A (en) * 2019-04-26 2019-07-12 广州恒雅生物化工有限公司 Crease-resistant Firm composition, crease-resistant Firm Essence and preparation method thereof
CN110115693A (en) * 2019-05-22 2019-08-13 上海璞萃生物科技有限公司 A kind of supermolecule peptide composition and preparation method thereof for anti-ageing anti-wrinkle
CN111035609A (en) * 2020-01-10 2020-04-21 上海赵小蝶化妆品有限公司 Micromolecular polypeptide eye essence and preparation method thereof
CN113786376A (en) * 2021-09-26 2021-12-14 湖北省麦诗特生物科技有限公司 Eye cream composition with eyeprint removing effect and preparation method thereof

Citations (1)

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CN102068391A (en) * 2010-12-30 2011-05-25 广州赛莱拉化妆品科技有限公司 Application of human steam cell growth factors in cosmetics

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN102068391A (en) * 2010-12-30 2011-05-25 广州赛莱拉化妆品科技有限公司 Application of human steam cell growth factors in cosmetics

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* Cited by examiner, † Cited by third party
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钟星 等: ""胜肽在化妆品中的应用和最新进展"", 《日用化学品科学》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108714123A (en) * 2018-06-15 2018-10-30 广州无添加主义化妆品有限公司 A kind of multiple-effect eye mask liquid, eye mask and preparation method thereof
CN109998939A (en) * 2019-04-26 2019-07-12 广州恒雅生物化工有限公司 Crease-resistant Firm composition, crease-resistant Firm Essence and preparation method thereof
CN110115693A (en) * 2019-05-22 2019-08-13 上海璞萃生物科技有限公司 A kind of supermolecule peptide composition and preparation method thereof for anti-ageing anti-wrinkle
CN111035609A (en) * 2020-01-10 2020-04-21 上海赵小蝶化妆品有限公司 Micromolecular polypeptide eye essence and preparation method thereof
CN113786376A (en) * 2021-09-26 2021-12-14 湖北省麦诗特生物科技有限公司 Eye cream composition with eyeprint removing effect and preparation method thereof

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Application publication date: 20180413