CN104042529A - Anti-allergic cosmetic composition and preparation method thereof - Google Patents
Anti-allergic cosmetic composition and preparation method thereof Download PDFInfo
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- CN104042529A CN104042529A CN201410325409.0A CN201410325409A CN104042529A CN 104042529 A CN104042529 A CN 104042529A CN 201410325409 A CN201410325409 A CN 201410325409A CN 104042529 A CN104042529 A CN 104042529A
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- 230000003266 anti-allergic effect Effects 0.000 title claims abstract description 34
- 239000000203 mixture Substances 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims description 8
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- 239000002562 thickening agent Substances 0.000 claims abstract description 5
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- 238000000605 extraction Methods 0.000 claims description 6
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- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 2
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 2
- 238000009413 insulation Methods 0.000 claims description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 2
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 2
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- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- 241000572565 Alpinia oxyphylla Species 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
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- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 241001336701 Elleanthus Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
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- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
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- Cosmetics (AREA)
Abstract
The invention discloses an anti-allergic cosmetic composition. The anti-allergic cosmetic composition comprises the following components in parts by weight: 1-15 parts of plant extract, 2.55-7 parts of emulsifier, 4-26 parts of emollient, 2.5-20 parts of humectant, 0.1-0.3 part of dipotassium glycyrrhizinate, 0.1-2 parts of silica, 0.03-0.07 part of potassium hydroxide, 0.1-0.2 part of thickener, 0.05-2 parts of antioxidant, 0.201-1.01 parts of preservative and 40-75 parts of water, wherein the plant extract is a mixed liquid of a lycopus lucidus extract and an alpinia oxyphylla extract. As the mixed liquid of the lycopus lucidus extract and the alpinia oxyphylla extract is applied to the anti-allergic cosmetic, the sensitive skin can be repaired effectively and the allergy symptoms of the skin can be improved.
Description
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of cosmetic composition with antianaphylaxis function and preparation method thereof.
Background technology
Cosmetics are to smear, spray or other similar methods, impose on any position of human body surface (skin, fingernail, lip, the ripe film in oral cavity etc.), with the product that reaches clean, eliminates bad smell, skin protection, beauty treatment and modification object.
Everybody has a love of beauty, and the mankind just have continuous pursuit since ancient times to the cosmetics that beautify self.But; many people's skin is sensitive skin now; the skin condition that height does not tolerate, be vulnerable to the stimulation of various factors and produce twinge, burn, the subjective symptom such as tight, pruritus, skin appearance is normal or can be with slight desquamation, erythema, dry etc.These are exactly our frequent said allergy, and skin allergy is the overreaction of cutaneous nerve when accepting unit and being upset.And the symptom that overreaction shows will badly influence the comfortable and attractive in appearance of people.
Along with the development of cosmetics industry, natural plants series products due to use safety, action temperature and, the advantage such as successful welcome.Be generally to obtain by corresponding processing the plant extract that contains effective ingredient, and add in cosmetics.
At present, antiallergic cosmetics antiallergic effect is on the market not obvious, even can increase the weight of allergic phenomena.Therefore, selecting which kind of plant, and being applied in cosmetics of its safety reached to better antiallergic effect, is problem demanding prompt solution.
Summary of the invention
Based on this, the object of the present invention is to provide a kind of antiallergic cosmetic composition.
Concrete technical scheme is as follows:
A kind of antiallergic cosmetic composition, is characterized in that, by weight, comprises following component:
Wherein, described plant extraction liquid is the mixed liquor of Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution.
In an embodiment, the weight portion of described plant extraction liquid is 5～12 parts therein; The weight part ratio of described Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution is (0.5～10): (0.5～10).
In an embodiment, the weight part ratio of described Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution is (2～10): (2～10) therein.
In an embodiment, described thickening agent is carbomer therein; Described antioxidant is tocopherol.
In an embodiment, described emulsifying agent is that weight part ratio is (1～3): (1～3): (0.5～3) therein: the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters/Pyrusussuriensis, the smooth olive oil acid esters of the smooth cetylate/Pyrusussuriensis of spermol cetylate/Pyrusussuriensis, cetearyl alcohol and the stearic mixing of (0.05～2).
In an embodiment, described emollient is that weight part ratio is (1～5): (0.5～5): (0.5～5): (1～5): (0.5～5) therein: the mixing of shea butter, olive oil, caprylic/capric triglyceride, squalane, ring five polydimethylsiloxane and the polydimethylsiloxane of (0.5～2).
In an embodiment, described wetting agent is that weight part ratio is (1～10): (1～10): (0.1～3): the mixing of glycerol, butanediol, trehalose and the hyaluronate sodium of (0.01～0.1) therein.
In an embodiment, described antiseptic is that weight part ratio is (0.2～1): the phenoxyethanol of (0.001～0.01) and the mixing of Methylisothiazolinone therein.
Herba Lycopi's extracting solution of the present invention and Fructus Alpiniae Oxyphyllae extracting solution can be by conventional alcohol extracting method preparations, ensure to greatest extent the antiallergic performance of two kinds of extracting solution with this, preferably following extracting method: dry plant (Herba Lycopi or Fructus Alpiniae Oxyphyllae) is added to deionized water by the mass ratio of 1:8～1:12, lixiviate 2～5h at 70～90 DEG C of temperature.Subsequently, extracting solution is filtered with filter cloth, more centrifugalize obtains plant (Herba Lycopi or Fructus Alpiniae Oxyphyllae) extracting solution.
The preparation method of above-mentioned antiallergic cosmetic composition, comprises the steps:
(1) emollient, emulsifying agent and antioxidant are dropped into oil phase pot, be heated to 70～85 DEG C, wait all components to melt rear insulation, obtain A phase;
(2) wetting agent, Silicon stone, thickening agent, glycyrrhizic acid dipotassium and water are dropped into emulsifying pot, be heated to 70～85 DEG C, be incubated 15～30 minutes, obtain B phase;
(3) by the emulsifying pot of the A phase suction step (2) in step (1), homogenizing 3～15 minutes, stir speed (S.S.) is 2000～4000rpm, then insulated and stirred 15～45 minutes, stir speed (S.S.) is 20～40rpm;
(4) emulsion in step (3) is cooled to 40～45 DEG C, adds sodium hydroxide, stir;
(5) add plant extraction liquid and antiseptic, stir, obtain antiallergic cosmetic composition.
Allergy is a kind of immunological diseases, is that in human body, immune function imbalance presents unbalanced situation.Allergic constitution patient, the time-division of investigation clinically, often find that multiple irritated repercussion disease is often found in same patient, with normal person's comparison, allergic constitution patients serum IgE (IgE) is showing and is raising, and the IgE receptor on the more and cell membrane of Number of Mast cells is also more.And a kind of semiochemicals that histamine is neurocyte to be discharged in the time being upset, the excessive release of histamine and the activity increase of IgE cell all can cause allergic phenomena.
Herba Lycopi has another name called tiger orchid, lycopus lucidus, red stalk grass etc., is the dry herb in ground of labiate lycopus lucidus.Herba Lycopi all has distribution in the most of place of China, and aboundresources, mainly originates in the ground such as Heilungkiang, Jilin, Liaoning, Hebei.Gather summer and autumn, dries.Herba Lycopi's extracting solution has inhibitory action to IgE cell, Herba Lycopi's extracting solution has inhibition to legionella pneumophilia, legionella pneumophilia is a class active bacterial infection under air conditioner surroundings, can cause scytitis or other inflammation, and the interaction energy of this two aspect effectively improves the allergic phenomena of skin.
Fructus Alpiniae Oxyphyllae has another name called Fructus Alpiniae Oxyphyllae, Fructus Alpiniae Oxyphyllae, is the fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae.When fruit is by green reddening between summer and autumn, gather, dry or cold drying.Main product is in Hainan Island, and there is a small amount of distribution in the Lezhou Peninsula, and there is cultivation in the provinces (district) such as Guangxi, Yunnan, Fujian.Fructus Alpiniae Oxyphyllae extract has inhibition to legionella pneumophilia, and legionella pneumophilia is to cause one of some dermopathic reasons under air conditioner surroundings, and Fructus Alpiniae Oxyphyllae extract can suppress the release of allergin histamine, thereby improves the allergic symptom of skin.
The glycyrrhizic acid dipotassium adding in antiallergic cosmetic composition of the present invention has good antiinflammatory antiallergic effect, can neutralize or lower the noxious substance of cosmetics, prevent anaphylaxis, share and can accelerate the absorption of skin to them and potentiation with emollient, wetting agent.
The emollient energy moistening skin adding in antiallergic cosmetic composition of the present invention, lubricated skin, protection and softening skin, and can improve the time of staying of moisture in skin; The effect of wetting agent is to form thin film at skin surface, and moisture content is sealed in skin to prevent water evaporates, does not hinder the absorption of skin for water in air part simultaneously, thereby keeps the suitable humidity of skin.
The following composition title that the application occurs is the title of INCI (International Nomenclaure Cosmetic Ingredient, i.e. international cosmetic raw material name) defined: the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters/Pyrusussuriensis, the smooth olive oil acid esters of the smooth cetylate/Pyrusussuriensis of spermol cetylate/Pyrusussuriensis and caprylic/capric triglyceride.
Advantage of the present invention is as follows:
Compared with prior art, antiallergic cosmetic composition of the present invention maintenance sensitive skin effectively, improves the allergic symptom of skin.
Detailed description of the invention
Below in conjunction with specific embodiment, present techniques scheme is described further.
The preparation of Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution:
Dry plant (Herba Lycopi) is added to deionized water by the mass ratio of 1:8, lixiviate 3h at 75 DEG C of temperature.Subsequently, extracting solution is filtered with filter cloth, then under rotating speed 3000r/min, centrifugalize 30 minutes, obtains Herba Lycopi's extracting solution.
Dry plant (Fructus Alpiniae Oxyphyllae) is added to deionized water by the mass ratio of 1:10, lixiviate 5h at 85 DEG C of temperature.Subsequently, extracting solution is filtered with filter cloth, then under rotating speed 3000r/min, centrifugalize 30 minutes, obtains Fructus Alpiniae Oxyphyllae extracting solution.
The formula of the antiallergic cosmetic composition of embodiment 1-3 and comparative example 1-3 is in table 1.
Table 1
The formula of the antiallergic cosmetic composition of embodiment 4-6 and comparative example 4-6 is in table 2.
Table 2
The formula of the antiallergic cosmetic composition of embodiment 7-9 and comparative example 7-9 is in table 3.
Table 3
The formula of the antiallergic cosmetic composition of embodiment 10-12 and comparative example 10-12 is in table 4.
Table 4
The cosmetics that above-described embodiment and comparative example make, try out 30 days continuously through 100 personnel of 30～55 years old respectively, and the antiallergic effect of prepared cosmetics in the various embodiments described above is evaluated in relative analysis.Wherein, described antiallergic effect is that skin is itched, the improvement situation of sensation of pricking, tight sense, erythema, tiny squama etc., the results are shown in Table 5.
Table 5
The cosmetic composition of above-described embodiment 1-12 and comparative example 1-12 is not all found zest and allergic phenomena in process on probation.
As known from Table 5: in embodiment each product to skin itch, the improvement degree of sensation of pricking, tight sense, erythema, tiny squama etc. is obviously high than the improvement degree of each product in matched group; And the weight portion of Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution is larger, improvement degree is higher, is 5～12 o'clock at the mixed liquor weight portion of Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution, and the cost performance of product is the highest.
The cosmetic composition of above-described embodiment 1-12 and comparative example 1-12 makes by following preparation method:
(1) above-mentioned A phase component is dropped into oil phase pot, be heated to 75 DEG C, wait all components to melt rear heat preservation for standby use;
(2) above-mentioned B phase component is dropped into emulsifying pot, be heated to 80 DEG C, be incubated 20 minutes;
(3) by step 1) in A phase suction step 2) emulsifying pot in, homogenizing (homogenizing stir speed (S.S.) is 3000rpm) insulated and stirred (stir speed (S.S.) is 30rpm) 25 minutes after 5 minutes;
(4) emulsion in step (3) is cooled to 40 DEG C, adds above-mentioned C phase component, stir;
(5) add D phase and E phase component, stir, obtain the cosmetics of antiallergic composition.
The above embodiment has only expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (9)
1. an antiallergic cosmetic composition, is characterized in that, by weight, comprises following component:
Wherein, described plant extraction liquid is the mixed liquor of Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution.
2. antiallergic cosmetic composition according to claim 1, is characterized in that, the weight portion of described plant extraction liquid is 5～12 parts; The weight part ratio of described Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution is (0.5～10): (0.5～10).
3. antiallergic cosmetic composition according to claim 2, is characterized in that, the weight part ratio of described Herba Lycopi's extracting solution and Fructus Alpiniae Oxyphyllae extracting solution is (2～10): (2～10).
4. according to antiallergic cosmetic composition described in claim 1-3 any one, it is characterized in that, described thickening agent is carbomer; Described antioxidant is tocopherol.
5. according to antiallergic cosmetic composition described in claim 1-3 any one, it is characterized in that, described emulsifying agent is that weight part ratio is (1～3): (1～3): (0.5～3): the smooth olive oil acid esters of cetearyl alcohol olive oil acid esters/Pyrusussuriensis, the smooth olive oil acid esters of the smooth cetylate/Pyrusussuriensis of spermol cetylate/Pyrusussuriensis, cetearyl alcohol and the stearic mixing of (0.05～2).
6. according to antiallergic cosmetic composition described in claim 1-3 any one, it is characterized in that, described emollient is that weight part ratio is (1～5): (0.5～5): (0.5～5): (1～5): (0.5～5): the mixing of shea butter, olive oil, caprylic/capric triglyceride, squalane, ring five polydimethylsiloxane and the polydimethylsiloxane of (0.5～2).
7. according to antiallergic cosmetic composition described in claim 1-3 any one, it is characterized in that, described wetting agent is that weight part ratio is (1～10): (1～10): (0.1～3): the mixing of glycerol, butanediol, trehalose and the hyaluronate sodium of (0.01～0.1).
8. according to the cosmetics of antiallergic composition described in claim 1-3 any one, it is characterized in that, described antiseptic is that weight part ratio is (0.2～1): the phenoxyethanol of (0.001～0.01) and the mixing of Methylisothiazolinone.
9. a preparation method for antiallergic cosmetic composition described in claim 1-9 any one, is characterized in that, comprises the following steps:
(1) emollient, emulsifying agent and antioxidant are dropped into oil phase pot, be heated to 70～85 DEG C, wait all components to melt rear insulation, obtain A phase;
(2) wetting agent, Silicon stone, thickening agent, glycyrrhizic acid dipotassium and water are dropped into emulsifying pot, be heated to 70～85 DEG C, be incubated 15～30 minutes, obtain B phase;
(3) by the emulsifying pot of the A phase suction step (2) in step (1), homogenizing 3～15 minutes, stir speed (S.S.) is 2000～4000rpm, then insulated and stirred 15～45 minutes, stir speed (S.S.) is 20～40rpm;
(4) emulsion in step (3) is cooled to 40～45 DEG C, adds sodium hydroxide, stir;
(5) add plant extraction liquid and antiseptic, stir, obtain antiallergic cosmetic composition.
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| CN104688631A (en) * | 2015-03-31 | 2015-06-10 | 苏州维泰生物技术有限公司 | Moisturizer for sensitive skin and preparation method thereof |
| CN105686978A (en) * | 2016-03-22 | 2016-06-22 | 广东嘉丹婷日用品有限公司 | Skin cleaning composition with lasting moisture maintaining effect |
| CN105878107A (en) * | 2016-04-13 | 2016-08-24 | 广州丹奇日用化工厂有限公司 | Skin-care product composition for sensitive skin |
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| CN109793697A (en) * | 2019-03-25 | 2019-05-24 | 韩兴旺 | A kind of Anti-allergic cosmetic composition and its preparation process containing plant active peptides |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104688631A (en) * | 2015-03-31 | 2015-06-10 | 苏州维泰生物技术有限公司 | Moisturizer for sensitive skin and preparation method thereof |
| CN105686978A (en) * | 2016-03-22 | 2016-06-22 | 广东嘉丹婷日用品有限公司 | Skin cleaning composition with lasting moisture maintaining effect |
| CN105686978B (en) * | 2016-03-22 | 2019-03-19 | 广东嘉丹婷日用品有限公司 | A kind of skin cleansing compositions of lasting moisturizing |
| CN105878107A (en) * | 2016-04-13 | 2016-08-24 | 广州丹奇日用化工厂有限公司 | Skin-care product composition for sensitive skin |
| CN105997566A (en) * | 2016-06-18 | 2016-10-12 | 广州丹奇日用化工厂有限公司 | Beautifying repairing cream containing herba cichorii polysaccharide and preparation method of cream |
| CN107260595A (en) * | 2017-06-01 | 2017-10-20 | 南京辅安堂药业有限公司 | One Plant Extracts antiallergy cream and preparation method thereof |
| CN107858205A (en) * | 2017-11-05 | 2018-03-30 | 成重任 | A kind of hydrosol liquid, processing method and the application of cordyceps sinensis ginseng |
| CN107823098A (en) * | 2017-12-08 | 2018-03-23 | 佛山实瑞先导材料研究院（普通合伙） | A kind of resisting skin allergy composition |
| CN109793697A (en) * | 2019-03-25 | 2019-05-24 | 韩兴旺 | A kind of Anti-allergic cosmetic composition and its preparation process containing plant active peptides |
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