CN107320419A - A kind of gentle reparation urea frost - Google Patents

A kind of gentle reparation urea frost Download PDF

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Publication number
CN107320419A
CN107320419A CN201710674713.XA CN201710674713A CN107320419A CN 107320419 A CN107320419 A CN 107320419A CN 201710674713 A CN201710674713 A CN 201710674713A CN 107320419 A CN107320419 A CN 107320419A
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urea
skin
reparation
gentle
frost
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CN107320419B (en
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袁观华
梁伟绍
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Guangzhou Mestract Bio-Tech Co Ltd
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Guangzhou Mestract Bio-Tech Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Epidemiology (AREA)
  • Birds (AREA)
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  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of gentle reparation urea frost, it is made up of skin quality conditioner component, helper component and water, the mass percent of the skin quality conditioner component is as follows:Cetearyl glucoside 1 3%, cetostearyl alcohol 2 5%, stearine 0.2 1%, the stearates 1 3% of PEG 100, tocopherol 0.1 1%, vaseline 3 8%, caprylic/capric triglyceride 5 10%, shea butter 4 9%, saualane 2 6%, Dormant oils 4 9%, allantoin 0.05 0.15%, urea 3 15%, hyaluronic acid 0.01 0.1%, glycerine 6 10%, propane diols 5 9%, bletilla striata root extract 1 5%, bisabolol 0.1 0.5%.The gentle reparation urea frost of the present invention, formula repairs the perfect adaptation of composition using urea and Chinese medicine, while reaching reparation chap skin, any stimulation and allergy will not be brought to skin, skin is gently nursed.

Description

A kind of gentle reparation urea frost
Technical field
The present invention relates to cosmetic field, a kind of gentle reparation urea frost is specifically related to.
Background technology
Autumn and winter dry season, trick is very easy to produce chap because of desiccation, the lighter's skin occur dry peel, Cracking, serious breach is deep to corium, causes bleeding and pain.At present, conventional product is urea frost, with preserving moisture and protecting skin, The antifreeze effect more split, there is good repairing effect to chapped skin.Most of product on the market, the addition of urea compares Height, while repairing skin, causes to stimulate, and bring other skin problems such as allergy to skin.Therefore, how urea frost is improved Gentle degree, its application could be improved, the problem of as current urgent need to resolve.
The content of the invention
In view of the shortcomings of the prior art and the puzzlement of above-mentioned skin surface pair is solved, it is an object of the invention to provide one The gentle perfect adaptation repaired urea frost, be formulated using urea and Chinese medicine reparation composition is planted, while reaching reparation chap skin, Any stimulation and allergy will not be brought to skin, skin is gently nursed.What the present invention was realized particular by following technical scheme:
A kind of gentle reparation urea frost, is made up of, the skin quality conditioner group skin quality conditioner component, helper component and water The mass percent divided is as follows:
Cetearyl glucoside:1-3%
Cetostearyl alcohol:2-5%
Stearine:0.2-1%
PEG-100 stearates:1-3%
Tocopherol:0.1-1%
Vaseline:3-8%
Caprylic/capric triglyceride:5-10%
Shea butter:4-9%
Saualane:2-6%
Dormant oils:4-9%
Allantoin:0.05-0.15%
Urea:3-15%
Hyaluronic acid:0.01-0.1%
Glycerine:6-10%
Propane diols:5-9%
Bletilla striata root extract:1-5%
Bisabolol:0.1-0.5%.
Further, helper component by odorant, preservative, thickener any one or more constitute.
The gentle application method for repairing urea frost of the invention:After clean skin, position needed for taking appropriate smear to absorption.
Gentle effect for repairing urea frost of the invention:Maintenance elasticity of skin, increase skin moisturizing and water lock degree, it is gentle to repair Chap skin.
Hyaluronic acid in the present invention, standard Chinese title:Sodium Hyaluronate (No. CAS:9004-61-9), lactic acid is passed through Coccus fermentation is made, and is one of composition of human body skin, is that the acid glutinous sugar of most wide one kind is distributed in human body, is present in connective group In the matrix knitted, with good moisture-keeping function.Have simultaneously and go to wrinkle, repair effect well.
Shea butter in the present invention, standard Chinese title:Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat (No. CAS:68920-03-6), its main component is triglycerides and unsaponifiable matters, and wherein unsaponifiable matters are main by Chinese cassia tree Acid esters and terpenol composition, with good anti-inflammatory and the effect for promoting human collagen albumen to synthesize, the skin that sallow can be made rough Skin becomes smooth exquisiteness.
Tocopherol in the present invention, standard Chinese title:Tocopherol (vitamin E) (No. CAS:59-02-9), with very strong Antioxidation, can also improve skin elasticity, anti-aging.
Vaseline in the present invention, standard Chinese title:Vaseline (No. CAS:8009-03-8), there is good water-resistance, in flesh Skin formation diaphragm, prevents moisture loss.
Saualane in the present invention, standard Chinese title:Saualane (No. CAS:111-01-3), have preferably affine to skin Property, allergy and stimulation will not be caused, other active components in formula can be accelerated to be permeated into skin.
Urea in the present invention, standard Chinese title:Urea (No. CAS:111-01-3), skin barrier can be strengthened, with excellent Elegant moisture-retaining capacity, makes dry skin become soft smooth flexible.
Bletilla striata root extract in the present invention, standard Chinese title:The bletilla striata (BLETILLA STRIATA) root extract, to skin Skin has a good repair, and activation can activate Skin Cell and powerful moistening effect, and this makes the bletilla striata in basic nursing and quick Sense skin nursing, skin repair field are yielded unusually brilliant results.
Bisabolol in the present invention, standard Chinese title:Bisabolol (No. CAS:515-69-5) there is anti-inflammatory, mitigate thorn Swash, it is pure natural, suitable for sensitive skin.
The gentle reparation urea frost of the present invention, complies fully with country's promulgation《Cosmetics safety technical specification》(2015 editions) In indices, said composition do not contain any noxious material.
The gentle reparation urea frost of the present invention, is that one kind can be applied directly to skin.It is mainly used in repairing chap skin.
Compared with prior art, the beneficial effect of gentle reparation urea frost of the invention is that formula uses urea and Chinese medicine The perfect adaptation of composition is repaired, while reaching reparation chap skin, any stimulation and allergy will not be brought to skin, gentle shield Manage skin.
Embodiment
The present invention is described in further detail with reference to embodiment.
Embodiment 1:
A kind of gentle reparation urea frost, is made up of the raw material of following percentage by weight:
Cetearyl glucoside:2%
Cetostearyl alcohol:3%
Stearine:0.5%
PEG-100 stearates:1.5%
Tocopherol:0.3%
Vaseline:4%
Caprylic/capric triglyceride:6%
Shea butter:5%
Saualane:2%
Dormant oils:5%
Allantoin:0.1%
Urea:15%
Hyaluronic acid:0.03%
Glycerine:8%
Propane diols:6%
Bletilla striata root extract:1%
Bisabolol:0.1%
Methyl hydroxybenzoate:0.15%
Nipasol:0.1%
Bis(hydroxymethyl)imidazolidinyl urea:0.03%
Essence:0.01%
Water:Surplus.
The above-mentioned gentle preparation method for repairing urea frost is as follows:
(1) water, glycerine, hyaluronic acid, urea, allantoin, propane diols, methyl hydroxybenzoate are placed on heated aqueous to 80-85 ℃;
(2) by cetearyl glucoside, cetostearyl alcohol, stearine, PEG-100 stearates, tocopherol, Vaseline, caprylic/capric triglyceride, shea butter, saualane, Dormant oils, Nipasol are placed on oil phase and are heated to 80-85 DEG C;
(3) first aqueous phase is pumped into emulsification pot, then oil phase is pumped into emulsification pot, adjust the temperature to 80 DEG C, homogeneous 5 minutes; Less than 45 DEG C, plus Bis(hydroxymethyl)imidazolidinyl urea, essence are then cooled to, is stirred more than 10 minutes;
(4) bletilla striata root extract, bisabolol are eventually adding, stirs to homogeneous and produces.
Comparative example 1~3:
The system of embodiment 1 is repeated by the content for the shea butter, bletilla striata root extract, bisabolol specified in table 1 below Preparation Method, the species and content of other unlisted components are identical, respectively obtain the different repair cream of component.
Table 1
Skin quality conditioner component Comparative example 1 Comparative example 2 Comparative example 3
Shea butter 5% Nothing Nothing
Bletilla striata root extract Nothing 1% Nothing
Bisabolol Nothing Nothing 0.1%
The embodiment of the present invention 1 and the Piglet s colibacillosis of the repair cream of comparative example 1~3:
(1) test object:60 volunteers, 25~45 years old age are chosen, skin has different degrees of drying, chap, Without skin disease and allergy medical history, non-sensitive skin can be by Normalization rule cosmetics, and cooperating personnel complete to comment on request Valency works, with certain expressive faculty, the impression after energy actual response use;It is randomly divided into 4 test groups, every group 15;
(2) application method:Each test group volunteer is individually using the embodiment of the present invention 1, comparative example 1~3 Repair cream, uses 2 times, continues 15 days daily;
(3) tester:VISA digital skins analyzer (U.S.), Mexameter MX18 dermal melanins and ferroheme Tester (Germany), MPA580 skin elasticities tester (Germany), Aomei health Y-B2006 moisture of skin tester (domestic);
(4) test event:Moisturizing degree, reparation degree, smoothness, elasticity;
(5) standards of grading are:Very satisfied 5 points (test result is compared to improvement degree before experiment more than 30%), is satisfied with 3 Divide (test result is in 20~30% compared to improvement degree before experiment), general 1 point (test result is preceding compared to experiment to be improved Degree is in 0~10%), it is unsatisfied with 0 point (test result compared to experiment before without any improvement);
(7) test result:Embodiment 1, the average of the repair cream of comparative example 1~3 the results are shown in Table 2:
Table 2
From the result of table 2, the gentle reparation urea frost of embodiment 1 improve skin moisture-keeping degree, reparation degree, smoothness, Elastic aspect has excellent effect.Pass through embodiment 1 and the result of the test of comparative example 1~3, it is seen then that the present invention is implemented The gentle reparation urea frost of example 1 with the addition of the shea butter 0.5%, bletilla striata root extract 1%, opopanax of following mass percent Alcohol 0.1%, the effect of Synergistic is generated in terms of skin moisture-keeping degree, reparation degree, smoothness, elasticity, this area is achieved The unexpected technique effect of technical staff.
Above-described embodiment is only currently preferred case study on implementation, it is impossible to model claimed of the invention is limited with this Enclose, any unsubstantiality and replacement that those skilled in the art is done on the basis of the present invention belongs to application claims The scope of protection.

Claims (4)

1. a kind of gentle reparation urea frost, is made up of, it is characterised in that the skin skin quality conditioner component, helper component and water The mass percent of matter conditioner component is as follows:
Cetearyl glucoside:1-3%
Cetostearyl alcohol:2-5%
Stearine:0.2-1%
PEG-100 stearates:1-3%
Tocopherol:0.1-1%
Vaseline:3-8%
Caprylic/capric triglyceride:5-10%
Shea butter:4-9%
Saualane:2-6%
Dormant oils:4-9%
Allantoin:0.05-0.15%
Urea:3-15%
Hyaluronic acid:0.01-0.1%
Glycerine:6-10%
Propane diols:5-9%
Bletilla striata root extract:1-5%
Bisabolol:0.1-0.5%.
2. a kind of gentle reparation urea frost according to claim 1, it is characterised in that helper component is by odorant, anti-corrosion Any one of agent, thickener or more is constituted.
3. a kind of gentle reparation urea frost according to claim 1 or 2, it is characterised in that by following percentage by weight Raw material is made:
Cetearyl glucoside:2%
Cetostearyl alcohol:3%
Stearine:0.5%
PEG-100 stearates:1.5%
Tocopherol:0.3%
Vaseline:4%
Caprylic/capric triglyceride:6%
Shea butter:5%
Saualane:2%
Dormant oils:5%
Allantoin:0.1%
Urea:15%
Hyaluronic acid:0.03%
Glycerine:8%
Propane diols:6%
Bletilla striata root extract:1%
Bisabolol:0.1%
Methyl hydroxybenzoate:0.15%
Nipasol:0.1%
Bis(hydroxymethyl)imidazolidinyl urea:0.03%
Essence:0.01%
Water:Surplus.
4. a kind of gentle reparation urea frost according to claim 3, it is characterised in that preparation method is as follows:
(1) water, glycerine, hyaluronic acid, urea, allantoin, propane diols, methyl hydroxybenzoate are placed on heated aqueous to 80-85 DEG C;
(2) by cetearyl glucoside, cetostearyl alcohol, stearine, PEG-100 stearates, tocopherol, all scholars Woods, caprylic/capric triglyceride, shea butter, saualane, Dormant oils, Nipasol are placed on oil phase and are heated to 80-85 DEG C;
(3) first aqueous phase is pumped into emulsification pot, then oil phase is pumped into emulsification pot, adjust the temperature to 80 DEG C, homogeneous 5 minutes;Then Less than 45 DEG C, plus Bis(hydroxymethyl)imidazolidinyl urea, essence are cooled to, is stirred more than 10 minutes;
(4) bletilla striata root extract, bisabolol are eventually adding, stirs to homogeneous and produces.
CN201710674713.XA 2017-08-08 2017-08-08 Mild repairing urea cream Active CN107320419B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107913217A (en) * 2017-11-17 2018-04-17 广州今盛美精细化工有限公司 A kind of Noni fruit ferment elite breast and preparation method thereof
CN108078841A (en) * 2017-12-25 2018-05-29 陕西佰傲再生医学有限公司 A kind of moisturiser of preservative free and preparation method thereof
CN108158859A (en) * 2018-02-02 2018-06-15 连云港市谭笑生物科技研究所 A kind of body maintenance frost
CN115463059A (en) * 2022-01-10 2022-12-13 陈启红 Mild and refreshing repairing composition and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265121A (en) * 2016-10-08 2017-01-04 广州丹奇日用化工厂有限公司 Leaf mustard polypeptide repairs the application in cosmetics in preparation whitening
CN106511249A (en) * 2016-12-24 2017-03-22 张涉应 Plant facial mask with efficacies of preserving moisture and whitening skin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265121A (en) * 2016-10-08 2017-01-04 广州丹奇日用化工厂有限公司 Leaf mustard polypeptide repairs the application in cosmetics in preparation whitening
CN106511249A (en) * 2016-12-24 2017-03-22 张涉应 Plant facial mask with efficacies of preserving moisture and whitening skin

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107913217A (en) * 2017-11-17 2018-04-17 广州今盛美精细化工有限公司 A kind of Noni fruit ferment elite breast and preparation method thereof
CN108078841A (en) * 2017-12-25 2018-05-29 陕西佰傲再生医学有限公司 A kind of moisturiser of preservative free and preparation method thereof
CN108158859A (en) * 2018-02-02 2018-06-15 连云港市谭笑生物科技研究所 A kind of body maintenance frost
CN115463059A (en) * 2022-01-10 2022-12-13 陈启红 Mild and refreshing repairing composition and preparation method thereof
CN115463059B (en) * 2022-01-10 2023-11-24 陈启红 Mild and refreshing repairing composition and preparation method thereof

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