CN102266280B - Application of refined deer oil to preparation of moisture preserving cosmetics - Google Patents

Application of refined deer oil to preparation of moisture preserving cosmetics Download PDF

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CN102266280B
CN102266280B CN2011102089548A CN201110208954A CN102266280B CN 102266280 B CN102266280 B CN 102266280B CN 2011102089548 A CN2011102089548 A CN 2011102089548A CN 201110208954 A CN201110208954 A CN 201110208954A CN 102266280 B CN102266280 B CN 102266280B
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deer
oil
deer oil
dermatitis
temperature
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CN102266280A (en
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胡耀辉
刘俊渤
王丽
刘俊梅
朴春红
于寒松
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Jilin Agricultural University
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Abstract

The invention relates to application of refined deer oil to the preparation of moisture preserving cosmetics, and belongs to application of economic animal oil in the field of the cosmetics. The deer oil has effects of skin moistening, moisture preserving and beauty treatment, and has the obvious curative effect on hormonal dermatitis, allergic dermatitis and atopic dermatitis. When the deer oil is used, the water retaining capacity of skin is enhanced, and desquamation, the hormonal dermatitis, the allergic dermatitis, the atopic dermatitis and the like which are caused by factors such as dry skin and the like are inhibited. After the cosmetics containing the deer oil are continuously used for a long time, the skin is moist, soft, smooth and tender and high in resilience, and weak skin quality is improved really.

Description

The application of refining deer oil in the preparation moisture-keeping cosmetics
Technical field
The present invention relates to the greasy application of a kind of special economic animal, especially refining Cervus nippon Temminck deer oil is in preparation moisture-keeping cosmetics Application for Field.
Background technology
Deer oil is the fatty oil of animal in deer family Cervus nippon Temminck, white solid under the room temperature, and body is softly soft, and main constituent is triglyceride.Already developing ground deer such as China northeast, northwest and the Inner Mongol has good geographical environmental condition, and especially Jilin Province is more with the Cervus nippon Temminck good variety, and production capacity forces its deer already to be developed has solid foundation and advantage.Along with the expansion in deer industry market and maturation progressively, the deer product demand is more and more vigorous, all has every year a large amount of deer oil to be not fully utilized as leftover bits and pieces.
Summary of the invention
The present invention provides the application of a kind of refining deer oil in the preparation moisture-keeping cosmetics.Its product healthy skin through repairing and strengthening the horny layer of epidermis barrier function, impels the skin moisture-keeping system to keep the horny layer water yield sufficient, simultaneously corticosteroid dermatitis, allergic dermatitis and atopic dermatitis etc. is had significant curative effect.
The application of refining deer oil in the preparation moisture-keeping cosmetics.
The application of refining deer oil in the cosmetics of preparation treatment corticosteroid dermatitis, allergic dermatitis and atopic dermatitis.
The refining deer oil that the present invention relates to is to extract through following technical proposal:
1), the deer body adipose tissue cleaned removes impurity, shred to particle diameter 1-2mm, drying and dehydrating; Supersound process: drying and dehydrating relative vacuum degree 0.08-0.09MPa; Under 90 ℃ of temperature, dry 1-3min is cooled to 45-50 ℃ then earlier; Dry again 90-100min, its water content of dry back is between 3%-7%; Through the 25-120KHz supersound process, ultrasonic temperature 35-40 ℃, ultrasonic time 15-20min;
2), in pretreated deer body adipose tissue, add percentage by weight 0.01%-0.04% sodium hydroxide wet method and boil and carry oil, temperature keeps boiling 90-150min between 50-110 ℃, melts thick deer oil;
3), thick deer oil is carried out vacuum decoloration, add 1: 1: 10 Powdered Activated Carbon of weight ratio, bentonite, zeolite be as decolorizing adsorbent, and bleaching temperature 90-95 ℃, decolouring relative vacuum degree 0.09MPa, bleaching time 20-30min, percent of decolourization 80-90%;
4), with thick deer oil coupling vacuum stripping distillation deodorize, relative vacuum degree 0.08-0.09MPa, temperature 130-150 ℃, time 4-6h obtains refining deer oil.
Refining deer oil room temperature is down for white solid state, and is tasteless, relative density 0.916, acid number (mg/g) 0.04-0.09, iodine number (g/100g) 37-40, moisture content<0.5%, saponification number (mg/g) 211-214, non-saponifiable matter<1.5%.
The refining deer oil of the present invention is used to prepare moisture-keeping cosmetics protection human epidermal; And when corticosteroid dermatitis, allergic dermatitis and atopic dermatitis etc. are treated, can be ointment, ointment, Emulsion, gel, cream, foam, solution, spray, facial film and synthetic detergent, shampoo, hair care agent etc.
When the refining deer oil of the present invention is used for moisture-keeping cosmetics, except that comprising conventional cosmetics carrier, can also comprise the additive that other are common, for example surfactant, thickening agent, binding agent, wetting agent, stabilizing agent, aromatic, antiseptic and conditioner etc.
Find the deer oil abundant nutrients after deliberation; Be rich in Palmic acid required in the body fat cell, stearic acid, oleic acid, linoleic acid; Can infiltrate keratodermatitis fast and directly replenish the lipid that this confluent monolayer cells film and iuntercellular play barrier function; Keep skin tissue cell (mainly being horn cell) and intercellular water content, strengthen the cuticlar water barrier function, make skin wet smooth; High resilience has significant curative effect for dermatosis such as corticosteroid dermatitis, allergic dermatitis and atopic dermatitiss simultaneously.
Along with improving constantly of living standard, people's the propensity to consume more and more tends to pursue nutrition, natural cosmetic raw materials.The deer oil composition is natural, has good trophism, affinity, permeability, can penetrate into subcutaneous tissue fast, repairs epidermis, prevents the epidermis water loss, has the epidermis cell of penetrating and still keeps its bioactive effect.Deer oil can enlarge the deer product applications as a kind of unique advanced skin care product additive, increases deer industry added value.
The invention has the advantages that: a kind of deer oil extractive technique of simplifying with respect to traditional extraction technique is provided, and the refining deer oil of gained is used to prepare the deer oil moisture-keeping cosmetics.Deer oil has the skin moistening beautification function of preserving moisture, and corticosteroid dermatitis, allergic dermatitis and atopic dermatitis are had obvious curative effects.The lipid material identical or similar with keratodermatitis cell membrane and iuntercellular lipid that is contained can infiltrate epidermis even intradermal fast and directly replenish the lipid of barrier action, and at skin surface formation continuous oil film, reduces or prevents the horny layer water loss; Promote the moisture that horny layer obtains spreading from lower-hierarchy; Contained bioactive ingredients can be removed free radical simultaneously, and the lipid and the lipoprotein of protection cell membrane are safeguarded the integrity of cell membrane and promoted tissue repair; The skin moisturizing ability is strengthened; Smooth soft and moist, high resilience, the inflammation such as corticosteroid dermatitis, allergic dermatitis and atopic dermatitis that factors such as inhibition xerosis cutis cause.After lasting use contains the moisture-keeping cosmetics of deer oil, fundamentally repair epidermis water barrier function, kept humidity of skin; Correct xerosis cutis, desquamation, chap and chap; Thereby make skin more moistening, soft, smooth, delicate, high resilience, and improve fragile skin matter conscientiously.
The specific embodiment
Embodiment 1
The refining deer oil that the present invention relates to is to extract through following technical proposal:
1), the deer body adipose tissue cleaned removes impurity, shred to particle diameter 1mm, drying and dehydrating; Supersound process: drying and dehydrating relative vacuum degree 0.08MPa, first under 90 ℃ of temperature, dry 1min; Be cooled to 45 ℃ then, dry again 90min, its water content of dry back is between 3%-7%; Through the 25KHz supersound process, 35 ℃ of ultrasonic temperature, ultrasonic time 15min;
2), in pretreated deer body adipose tissue, add percentage by weight 0.01% sodium hydroxide wet method and boil and carry oil, temperature keeps boiling 90min between 50 ℃, melts thick deer oil;
3), thick deer oil is carried out vacuum decoloration, add 1: 1: 10 Powdered Activated Carbon of weight ratio, bentonite, zeolite be as decolorizing adsorbent, 90 ℃ of bleaching temperatures, decolouring relative vacuum degree 0.09MPa, bleaching time 20min, percent of decolourization 80%;
4), with thick deer oil coupling vacuum stripping distillation deodorize, relative vacuum degree 0.08MPa, 130 ℃ of temperature, time 4h obtains refining deer oil.
Refining deer oil room temperature is down for white solid state, and is tasteless, relative density 0.916, acid number (mg/g) 0.04-0.09, iodine number (g/100g) 37-40, moisture content<0.5%, saponification number (mg/g) 211-214, non-saponifiable matter<1.5%.
Embodiment 2
1), the deer body adipose tissue cleaned removes impurity, shred to particle diameter 2mm, drying and dehydrating; Supersound process: drying and dehydrating relative vacuum degree 0.09MPa, first under 90 ℃ of temperature, dry 2min; Be cooled to 48 ℃ then, dry again 95min, its water content of dry back is between 3%-7%; Through the 70KHz supersound process, 37 ℃ of ultrasonic temperature, ultrasonic time 18min;
2), in pretreated deer body adipose tissue, add percentage by weight 0.02% sodium hydroxide wet method and boil and carry oil, temperature keeps boiling 120min between 80 ℃, melts thick deer oil;
3), thick deer oil is carried out vacuum decoloration, add 1: 1: 10 Powdered Activated Carbon of weight ratio, bentonite, zeolite be as decolorizing adsorbent, 92 ℃ of bleaching temperatures, decolouring relative vacuum degree 0.09MPa, bleaching time 25min, percent of decolourization 85%;
4), with thick deer oil coupling vacuum stripping distillation deodorize, relative vacuum degree 0.09MPa, 140 ℃ of temperature, time 5h obtains refining deer oil.
Embodiment 3
1), the deer body adipose tissue cleaned removes impurity, shred to particle diameter 2mm, drying and dehydrating; Supersound process: drying and dehydrating relative vacuum degree 0.08MPa, first under 90 ℃ of temperature, dry 3min; Be cooled to 50 ℃ then, dry again 100min, its water content of dry back is between 3%-7%; Through the 120KHz supersound process, 40 ℃ of ultrasonic temperature, ultrasonic time 20min;
2), in pretreated deer body adipose tissue, add percentage by weight 0.04% sodium hydroxide wet method and boil and carry oil, temperature keeps boiling 150min between 110 ℃, melts thick deer oil;
3), thick deer oil is carried out vacuum decoloration, add 1: 1: 10 Powdered Activated Carbon of weight ratio, bentonite, zeolite be as decolorizing adsorbent, 95 ℃ of bleaching temperatures, decolouring relative vacuum degree 0.09MPa, bleaching time 30min, percent of decolourization 90%;
4), with thick deer oil coupling vacuum stripping distillation deodorize, relative vacuum degree 0.09MPa, 150 ℃ of temperature, time 6h obtains refining deer oil.
Application implementation example 1 deer oil moisturizing emulsion
Prescription: see table 1
Table 1 deer oil moisturizing emulsion prescription
Figure BDA0000078368150000041
Method for preparing: after component A and B component be warming up to 85 ℃ respectively, component A insulation, B component is warming up to 90 ℃ of sterilization 15min again; B component is put into emulsator and is constantly stirred, and slowly adds component A, and constant temperature stirs the back fast cooling and adds component C; Continue to be stirred to room temperature, make the deer oil moisturizing emulsion.
The application implementation example 2 deer oil essence of preserving moisture
Prescription: see table 2
The table 2 deer oil essence prescription of preserving moisture
Figure BDA0000078368150000051
Method for preparing: B component is stirred to clarify at low temperatures; Component A, component C are heated to dissolving back sterilization fully; Slowly add successively be stirred to dissolving fully in the B component after, reduce to 40-50 ℃ and add component D again and continue to be stirred to room temperature, make the deer oil essence of preserving moisture.
The application implementation example 3 deer oil day cream of preserving moisture
Prescription: see table 3
The table 3 deer oil day cream prescription of preserving moisture
Figure BDA0000078368150000052
Method for preparing: with component A heat temperature raising to 75 ℃-85 ℃ of mix homogeneously of formula ratio; The B component heat temperature raising to 85 of getting formula ratio stirs by ℃-90 ℃, and it is subsequent use to sterilize, under 70 ℃-85 ℃ of temperature, whole A are slowly added mutually be stirred to emulsifying fully in the B component after, add component C and continue to be stirred to room temperature, make the deer oil day cream of preserving moisture.
The moisture-keeping cosmetics that contains deer oil that the present invention relates to, the concrete test method of its moistening effect is following:
Deer oil is preserved moisture product as sample in the foregoing description 1~3, sample 1: the deer oil moisturizing emulsion; Sample 2: the deer oil essence of preserving moisture; Sample 3: the deer oil day cream of preserving moisture; Control samples is three kinds of moisture-keeping cosmetics of stochastic buying from the market, measures the rate of preserving moisture of product respectively.
Will be by saturated K 2CO 3Aqueous solution places 22 ℃ of isoperibols as the exsiccator of relative humidity (RH) 60%, and medical air-permeable adhesive tape is affixed on 7.5cm * 7.5cm glass plate, in 80 ℃ of baking ovens, dries to constant weight, and sample is got 0.4000g, is equivalent to 7.0mg/cm 2Quantity of sample is coated in equably on the breathable adhesive tape of glass plate, puts in the exsiccator and weigh at set intervals, calculate the rate of preserving moisture.Test determination the preserve moisture rate of product in 24h, 3 results' meansigma methods is got in the experiment parallel repetition 3 times of at every turn preserving moisture, its test result is seen table 4.
Calculate: the rate of preserving moisture (%)=M 2/ M 1* 100%
In the formula: M 2Place back moisture weight (g)
M 1Moisture weight (g) before placing
Table 4 different product is at the RH60% rate % (22 ℃ of room temperatures) that preserves moisture
Figure BDA0000078368150000061
Result of the test shows: the cosmetics that contained deer oil in 24 hours are preserved moisture rate between 20.0%-70.0%; The plain edition cosmetics rate of preserving moisture than buying on the market exceeds about 10.0-30.0%, and the moisture-keeping cosmetics that therefore contains deer oil has fabulous moistening effect.
The cosmetics that contain deer oil that the present invention relates to, following to corticosteroid dermatitis, allergic dermatitis and treatment of atopic dermatitis effect:
1, physical data
The sick kind: desquamation 30 examples, corticosteroid dermatitis 30 examples, allergic dermatitis 30 examples, atopic dermatitis 30 examples.
Sex: women's 120 examples.
Age: 25 years old~30 years old, 10 examples; 30 years old~35 years old, 25 examples; 35 years old~40 years old, 25 examples; 40 years old~45 years old, 30 examples; 45 years old~50 years old, 30 examples.
The course of treatment: one the course of treatment cured person 48 examples, produce effects 44 examples, effective 22 examples, invalid 6 examples.
Normal person's group: routine 30 examples of woman.
2, the course of treatment and method for using
The course of treatment: be a course of treatment all around.
Method for using: deer oil moisturizing emulsion and deer oil are preserved moisture essence every day 2 times, each 1 time sooner or later, evenly are applied to face; Deer oil is preserved moisture day cream every day early 1 time, evenly is applied to face.
3, curative effect determinate standard
Cure: desquamation or inflammation disappear more than 90%, and disease symptoms obviously improves
Produce effects: desquamation or inflammation disappear 70%~90%, and disease symptoms improves.
Effectively: desquamation or inflammation disappear 30~70%, and disease symptoms makes moderate progress.
Invalid: desquamation or inflammation disappear below 30%, and disease symptoms improves very little.
4, therapeutic effect is seen table 5
The routine treating skin disease effect of table 5100
Figure BDA0000078368150000071
5, normal person's observed result is seen table 6
The routine normal person's observed result of table 630
Figure BDA0000078368150000072
6, conclusion
Deer oil has the skin moistening beautification function of preserving moisture, and corticosteroid dermatitis, allergic dermatitis and atopic dermatitis are had significant curative effect.Contain lipid material and can infiltrate epidermis even intradermal fast and directly replenished the lipid of barrier action; Reduce or prevent the horny layer water loss; Promote the moisture that horny layer obtains spreading from lower-hierarchy; Contained bioactive ingredients can be removed free radical simultaneously, and the lipid and the lipoprotein of protection cell membrane are safeguarded the integrity of cell membrane and promoted tissue repair; The skin moisturizing ability is strengthened, desquamation, corticosteroid dermatitis, allergic dermatitis and atopic dermatitis etc. that factors such as inhibition xerosis cutis cause.After lasting use contains the cosmetics of deer oil, can make skin more moistening, soft, smooth, delicate, high resilience, and improve fragile skin matter conscientiously.
7, model case
Case one:
Zhang, the woman, 39 years old, the salesman, skin of face is coarse, desquamation once used other product effects of preserving moisture not remarkable, with outer sooner or later being coated with deer oil moisturizing emulsion every day, use a week continuously after, the desquamation symptom all disappears, the appearance skin moisturizing is moist.
Case two:
Cross certain, woman, 32 years old; The company clerk, because of facial seborrheic dermatitis, frequent external " PIYANPING " etc.; Half a year, rear face was to thermo-responsive, and is often red and swollen, is diagnosed as steroid-dependent dermatitis; With deer oil outer sooner or later being coated with essence every day of preserving moisture, use continuously two week the back red swelling of the skins and subjective symptoms improvement is all arranged.The bimester after, it is normal that skin recovers.
Case three:
The Wang, the woman, 45 years old, the university teacher, because of serious drying of skin and allergic constitution, face has erythema, is diagnosed as atopic dermatitis, is coated with outward every day with the deer oil day cream of preserving moisture, and uses all rear face erythema to reduce continuously, and skin wet is soft.After two weeks, it is normal that skin recovers.

Claims (1)

1. the application of refining deer oil in the cosmetics of preparation treatment corticosteroid dermatitis, allergic dermatitis and atopic dermatitis, the method for preparing of said refining deer oil is following:
1), the deer body adipose tissue cleaned removes impurity, shred to particle diameter 1-2mm, drying and dehydrating; Supersound process: drying and dehydrating relative vacuum degree 0.08-0.09MPa; Under 90 ℃ of temperature, dry 1-3min is cooled to 45-50 ℃ then earlier; Dry again 90-100min, its water content of dry back is between 3%-7%; Through the 25-120KHz supersound process, ultrasonic temperature 35-40 ℃, ultrasonic time 15-20min;
2), in pretreated deer body adipose tissue, add percentage by weight 0.01%-0.04% sodium hydroxide wet method and boil and carry oil, temperature keeps boiling 90-150min between 50-110 ℃, melts thick deer oil;
3), thick deer oil is carried out vacuum decoloration, add the Powdered Activated Carbon of weight ratio 1:1:10, bentonite, zeolite be as decolorizing adsorbent, and bleaching temperature 90-95 ℃, decolouring relative vacuum degree 0.09MPa, bleaching time 20-30min, percent of decolourization 80-90%;
4), with thick deer oil coupling vacuum stripping distillation deodorize, relative vacuum degree 0.08-0.09MPa, temperature 130-150 ℃, time 4-6h obtains refining deer oil.
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CN106109269B (en) * 2016-06-29 2018-12-07 李华忠 The cosmetics and skincare product of deer oil and antler polypeptide compatibility, preparation method and application
CN107245394A (en) * 2017-05-18 2017-10-13 吉林农业大学 A kind of Multifunctional cold handmade soap containing the fiery sesame oil of deer oil and preparation method thereof
KR101998621B1 (en) * 2017-11-08 2019-09-27 주식회사 바이오스탠다드 Extraction method of deer fat mixed extract and cosmetic composition including the same
CN107739654A (en) * 2017-11-14 2018-02-27 苏洁 A kind of method of low-temperature purifying method deer oil
CN107997985A (en) * 2017-12-07 2018-05-08 吉林农业大学 Application of the deerskin polysaccharide in moisture-keeping cosmetics are prepared
CN108559625A (en) * 2018-01-19 2018-09-21 东北师范大学 Dry fractionation deer is oily and is applied in preparing skin care item
CN110090175A (en) * 2019-04-19 2019-08-06 吉林省东鳌鹿业科技开发有限公司 A kind of deer pasta film and preparation method thereof

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