CN106580762A - Skincare product composition with wrinkle smoothing and preventing effects, eye cream with wrinkle smoothing and preventing effects, and production method of eye cream - Google Patents
Skincare product composition with wrinkle smoothing and preventing effects, eye cream with wrinkle smoothing and preventing effects, and production method of eye cream Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
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Abstract
The invention relates to a skincare product composition with wrinkle smoothing and preventing effects, an eye cream with wrinkle smoothing and preventing effects, and a production method of the eye cream. The skincare product composition with wrinkle smoothing and preventing effects comprises Cedrus atlantica bark extract, seaweed extract and astaxanthin; and a mass ratio of the Cedrus atlantica bark extract to the seaweed extract to the astaxanthin is (0.2-5):(0.1-5):(0.01-0.5). The skincare product composition with wrinkle smoothing and preventing effects can be applied to the eye cream in order to integrally provide many nutrient components to eye skins, make the nutrient components easy to absorb, can effectively reduce irritation to eye skins, effectively removes or alleviates eye wrinkles, and improves the moisture retention effect and the elasticity of the skins.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of with skin care item group compound, the eye of comforting the crease-resistant effect of stricture of vagina
Frost and preparation method thereof.
Background technology
Wrinkle refers to that skin is affected by external environment, forms free free radical, free radical destruction normal cell membrane tissue
Interior collagen protein, active substance, oxidative cell and formed little microgroove, wrinkle.Facial wrinkles are divided into atrophy wrinkle and hypertrophy
Wrinkle two types.Atrophy wrinkle is referred to and occurs in thin, easy jackknifing and the wrinkle on dry skin, such as those nothings of circumference of eyes
The tiny wrinkle of number；Loose wrinkle refers to the wrinkle occurred in oily skin, and quantity is few, and texture is close and deep.Wherein, eye
Skin is the most thin skin of human body, very careful and fragile, it is easy to come to harm.
In addition, existing eye cream composition mainly based on emulsification system, can add the emulsifying agent will during eye cream is prepared
Together with oil phase is blended with water, the emulsifying agent major part for using on the market is artificial synthetic emulsifier, easily causes skin
The problems such as stimulation, allergy.Eye part skin can be more sensitive to stimulating, and researches and develops a gentle non-stimulated eye cream and has certain city
Field value.
The content of the invention
Based on this, it is necessary to provide a kind of with comforting composite skin care product, eye cream of the crease-resistant effect of stricture of vagina and preparation method thereof.
Concrete technical scheme is as follows：
It is a kind of with the composite skin care product for comforting the crease-resistant effect of stricture of vagina, comprising following components：Atlas cedar bark extract, sea
Algae seed extract and astaxanthin；The mass ratio of the Atlas cedar bark extract, Sargassum seed extract and astaxanthin is 0.2-
5：0.1-5：0.01-0.5.
It is wherein in some embodiments, described also to include acetyl group six with the composite skin care product for comforting the crease-resistant effect of stricture of vagina
One or more in peptide -8, plant sterol, artemia extract or yeast fermented product extract.
Wherein in some embodiments, the Atlas cedar bark extract, Sargassum seed extract, astaxanthin and yeast are sent out
The mass ratio of ferment extract is 0.2-5：0.1-5：0.01-0.5：0.5-1.
Wherein in some embodiments, the Atlas cedar bark extract, Sargassum seed extract, astaxanthin and yeast are sent out
The mass ratio of ferment extract is 1.2：1.5：0.2：0.8.
It is above-mentioned to prepare with skin care item or the change for comforting the crease-resistant effect of stricture of vagina with the composite skin care product for comforting the crease-resistant effect of stricture of vagina
Application in cosmetic.
It is a kind of with the eye cream for comforting the crease-resistant effect of stricture of vagina, prepared by acceptable adjuvant in above-mentioned composite skin care product and eye cream
Form.
Wherein in some embodiments, it is described with comfort the eye cream of stricture of vagina effect prepared by the raw material of following mass percent and
Into：Composite skin care product 0.8%-8%, plant source wedding agent 2%-5% described in any one of Claims 1-4, antioxidant
The deionized water of 0.1%-3%, wetting agent 1%-5%, thickening agent 0.2%-1%, vegetable oil 5%-10% and surplus.
Wherein in some embodiments, the plant source wedding agent is selected from lecithin, alkyl androstanediol, inulin ester or Fructus Citri Limoniae
One or more in acid esters；
The one kind or many of the thickening agent in sodium polyacrylate, xanthan gum, hydroxyethyl cellulose or methylcellulose
Kind；
The vegetable oil selected from Jojoba oil, Semen pruni armeniacae oil, olive oil, camellia seed oil, Semen Tritici aestivi germ oil, safflower oil,
One or more in Oleum Vitis viniferae or white Limnanthes Alba Seed Oil；
The antioxidant is in tocopherol, Ubidecarenone, beta-carotene, lycopene, tea polyphenols or vitamin C
One or more；
The wetting agent is protected selected from hyaluronate sodium, pyrrolidone sodium carboxylate, ceramide, Sargassum extract, aminoacid
One or more in humectant, glycerol caprylate or 1,2- hexanediol.
Wherein in some embodiments, the plant source wedding agent selected from soybean lecithin, cetearyl glucoside and
The mixture of inulin lauryl carbamate：The vegetable oil is selected from the mixed of Jojoba oil, safflower oil and white Limnanthes Alba Seed Oil
Compound；Mixture of the antioxidant selected from Ubidecarenone, lycopene and tea polyphenols；The wetting agent is selected from hyaluronic acid
The mixture of sodium, ceramide, glycerol caprylate and 1,2- hexanediol；The thickening agent is selected from sodium polyacrylate and xanthan gum
Mixture.
The above-mentioned preparation method with the eye cream for comforting the crease-resistant effect of stricture of vagina, by composite skin care product described above and adjuvant Jing
System breast is mixed, is obtained final product.
The present invention has the advantages that：
The long-term experience accumulation of Jing inventor and substantial amounts of experimentation, it is of the present invention with comforting the crease-resistant effect of stricture of vagina
Composite skin care product includes Atlas cedar bark extract, Sargassum seed extract and astaxanthin, triplicity, with good association
With crease-resistant effect.
The present invention by screen natural origin, gentle above-mentioned composite skin care product, wetting agent, plant source wedding agent and
The compounding of vegetable oil, makes without synthetic oil, essence and preservative in the formula system of eye cream, without acrylamide list
Body, provides more nutritional labelings to eye skin, it is easy to absorb, and can effectively reduce the thorn to eye skin on the whole
Swash, improve the cuticular moisture content of eye, improve moisturizing and wrinkle removing effect of compacting, strengthen skin elasticity, can effectively reduce right
The stimulation of eye skin, and with salubrious skin sense, effectively remove or alleviate eye wrinkle-removing.
The preparation process with the eye cream for comforting the crease-resistant effect of stricture of vagina of the present invention is simple, reliable, and the eye cream of preparation being capable of heatproof
Degree change, good stability are adapted to industrialized production.
Description of the drawings
Nothing.
Specific embodiment
Below in conjunction with specific embodiment to the present invention with composite skin care product, eye cream and its system for comforting the crease-resistant effect of stricture of vagina
Preparation Method is further described in detail.
Raw material sources
Atlas cedar bark extract, hundred Hao Bo company limiteies of Guangzhou
Nipa palm seed extract, hundred Hao Bo company limiteies of Guangzhou
Argireline, celestial graceful (world) company limited
Plant sterol, Guangzhou You Ran bio tech ltd
Astaxanthin, Guangzhou day of snow of oozing use Chemical Co., Ltd.
Artemia extract, Guangzhou Rong Dao Chemical Co., Ltd.s
Yeast fermented product extract, celestial graceful (world) company limited
Other adjuvants are also commercially available prod.
Embodiment 1
A kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina is provided, 1 is shown in Table.
The formula table of the eye cream of 1 embodiment 1 of table
Eye cream is prepared according to the formula in table 1 below, is comprised the steps：
(1) A phase components are added in oil phase pot and is warming up to 80 DEG C, be incubated 10min, obtain oil phase mixed liquor；
(2) B phase components are sequentially added and in water phase pot, is warming up to 85 DEG C, homogenizing 5min is incubated 30min, obtains water and mix
Liquid；
(3) water that 3/4 times of above-mentioned cumulative volume is measured is mixed in liquid suction emulsifying pot, opens the stirring of emulsifying pot, stirring
Speed is 1500rap/min, under agitation, slowly by emulsifying after oil phase mixed liquor suction emulsifying pot, then will be remaining overall
The water of 1/4 times of long-pending amount is mixed in liquid suction emulsifying pot；
After homogenizing 5min, then 10min is persistently stirred, mixing speed is 1500rap/min；
(4) cooling water is opened, after pot temperature to be emulsified is down to 45 DEG C, adds C phase components stirring 10min, mixing speed
1000rap/min；
(5) D phase components stirring 10min is added, room temperature is cooled to, is discharged, obtain final product.
Embodiment 2
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 2.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The formula table of the eye cream of 2 embodiment 2 of table
Embodiment 3
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 3.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The no added bright eyes of 3 embodiment 3 of table comfort the formula table of stricture of vagina anti-wrinkle eye cream
Embodiment 4
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 4.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The no added bright eyes of 4 embodiment 4 of table comfort the formula table of stricture of vagina anti-wrinkle eye cream
Embodiment 5
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 5.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The no added bright eyes of 5 embodiment 5 of table comfort the formula table of stricture of vagina anti-wrinkle eye cream
Embodiment 6
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 6.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The no added bright eyes of 6 embodiment 6 of table comfort the formula table of stricture of vagina anti-wrinkle eye cream
Embodiment 7
The present embodiment provides a kind of formula with the eye cream for comforting the crease-resistant effect of stricture of vagina, is shown in Table 7.Should have and comfort the crease-resistant effect of stricture of vagina
Eye cream preparation method referring to embodiment 1.
The no added bright eyes of 7 embodiment 7 of table comfort the formula table of stricture of vagina anti-wrinkle eye cream
Embodiment 8
Stability analyses are carried out to embodiment 1-7, and standard is performed with reference to skin moistening cream QB/T 1857-2013 is carried out, and is counted
The results are shown in Table 8.
(1) resistance to Thermal test
The no added bright eyes that Example 1-7 is produced are comforted stricture of vagina anti-wrinkle eye cream and are placed under 48 DEG C of environment, observe after standing 90 days.
(2) resist cold and test
The no added bright eyes that Example 1-7 is produced are comforted stricture of vagina anti-wrinkle eye cream and are placed under -10 DEG C of environment, see after standing 90 days
Examine.
(3) cold and heat loop test：
The no added bright eyes that Example 1-7 is produced are comforted stricture of vagina anti-wrinkle eye cream and are placed under 48 DEG C of environment, stand 12h；Again will be real
Apply the no added bright eyes that a 1-7 produces and comfort stricture of vagina anti-wrinkle eye cream and be placed under -10 DEG C of environment；Continuously repeat this circulation three times.
8 no added bright eyes of table comfort the stability study of stricture of vagina anti-wrinkle eye cream
As shown in Table 8, what prepared by embodiment 1-7 low temperature resistant can change with high temperature with the eye cream for comforting the crease-resistant effect of stricture of vagina,
Good stability.
Embodiment 9
Hypersensitive test
Healthy albino guinea-pig is taken, body weight 250-300g, male and female dual-purpose reject both sides dorsal body setae before test, per 3 × 3cm of side, with
Machine is divided into test group 1 to 7, blank control group and positive controls.Eye cream of the test group 1 to 7 using the embodiment of the present invention 1 to 7；
Positive controls DNFB, sensitization are 1% using its mass concentration, and it is 0.1% to excite using its mass concentration.
The eye cream for taking the embodiment of the present invention 1 to 7 is applied to back and goes to hair-fields, the next day 1 time, totally 3 times.14 after last contact
My god, at back, the same area smears the eye cream, is at once observed after removing medicine after 6h, and whether there is in 24h, 48h, 72h observation
Quick reaction.Blank control group and the same method of positive controls excite contact and observe.
Result of the test：
The animal skin of positive controls occurs localized erythema and slight edema, 24h anaphylaxiss after sensitization 1h
Exacerbation of symptoms, sensitization rate are 100%.There is not any symptoms of allergic in test group and blank control group animal skin, cause
Quick rate is 0%.
Test result indicate that the formula with the eye cream for comforting the crease-resistant effect of stricture of vagina of the present invention is gentle, non-stimulated.
10 eye cream measure of merit of embodiment
(1) comfort the crease-resistant measure of merit of stricture of vagina
The eye cream of user above-described embodiment 1 to 7 is determined respectively using after 60d, and statistics is using zest incidence rate and resists
Wrinkle effect effective percentage, statistical result are shown in Table 9.Its criterion of therapeutical effect is as follows：
It is effective：Skin smooth high resilience, wrinkle are substantially desalinated, and little microgroove disappears；
Effectively：Skin is relatively smooth, and elasticity makes moderate progress, and little microgroove is substantially desalinated, but wrinkle is still present；
It is invalid：Little microgroove, wrinkle are still present, or even have the trend of intensification.
9 anti-wrinkle effect statistical table of table
| Group | Effective number | Efficiently individual quantity | Invalid number | Effective percentage |
| Embodiment 1 | 5 | 10 | 5 | 75% |
| Embodiment 2 | 6 | 11 | 3 | 85% |
| Embodiment 3 | 7 | 8 | 5 | 75% |
| Embodiment 4 | 6 | 9 | 5 | 75% |
| Embodiment 5 | 6 | 12 | 4 | 80% |
| Embodiment 6 | 9 | 10 | 1 | 95% |
| Embodiment 7 | 1 | 8 | 11 | 45% |
(2) eye part skin moisturizing and skin elasticity measure of merit
Age is met into tested standard volunteer between 30-35 year, is randomly assigned as 7 groups, 20 per group.Volunteer is every
Day smears eye cream according to correct maneuver after cleaning sooner or later face.
User the 0th week and 4th week, the water content of eye part skin, using moisture of skin tester (Germany are determined respectively
CK, CM825-MDD), when determining indices, room temperature is 20 DEG C～25 DEG C, and humidity is 35%～70%, and is required tested
Person shifts to an earlier date 30min and enters test environment, and the measurement of indices is carried out after rest.Per group of embodiment is averaged, statistics knot
Fruit is shown in Table 10.
10 moistening effect statistical table of table
| Group | Water content of stratum corneum the 0th week | Water content of stratum corneum the 4th week |
| Embodiment 1 | 60.17 | 65.21 |
| Embodiment 2 | 61.23 | 67.81 |
| Embodiment 3 | 60.88 | 66.08 |
| Embodiment 4 | 62.01 | 67.45 |
| Embodiment 5 | 61.55 | 66.10 |
| Embodiment 6 | 60.96 | 70.05 |
| Embodiment 7 | 60.46 | 64.72 |
User the 0th week and 4th week, the water content of eye part skin, using skin elasticity tester are determined respectively
Cutometer MPA580 (German CK companies) are tested to the volunteer of per group of embodiment, and statistical result is shown in Table 11.
11 skin elasticity effect statistical table of table
| Group | Water content of stratum corneum the 0th week | Water content of stratum corneum the 4th week |
| Embodiment 1 | 57.41 | 68.69 |
| Embodiment 2 | 58.02 | 71.23 |
| Embodiment 3 | 56.98 | 70.10 |
| Embodiment 4 | 57.11 | 70.91 |
| Embodiment 5 | 57.36 | 69.02 |
| Embodiment 6 | 56.67 | 73.59 |
| Embodiment 7 | 57.86 | 63.50 |
From table 9 to table 11, compared with Example 7, the no added bright eyes of embodiment 1-6 are comforted stricture of vagina anti-wrinkle eye cream and are respectively provided with
Moistening effect, can effectively strengthen the elasticity of eye part skin well, hence it is evident that the effect with the wrinkle removing that compacts, smooth skin.
Each technical characteristic of embodiment described above arbitrarily can be combined, to make description succinct, not to above-mentioned reality
Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, the scope of this specification record is all considered to be.
Embodiment described above only expresses the several embodiments of the present invention, and its description is more concrete and detailed, but and
Therefore can not be construed as limiting the scope of the patent.It should be pointed out that for one of ordinary skill in the art comes
Say, without departing from the inventive concept of the premise, some deformations and improvement can also be made, these belong to the protection of the present invention
Scope.Therefore, the protection domain of patent of the present invention should be defined by claims.
Claims (10)
1. it is a kind of with the composite skin care product for comforting the crease-resistant effect of stricture of vagina, it is characterised in that comprising following components：Atlas cedar bark
Extract, Sargassum seed extract and astaxanthin；The quality of the Atlas cedar bark extract, Sargassum seed extract and astaxanthin
Than for 0.2-5：0.1-5：0.01-0.5.
2. it is according to claim 1 with the composite skin care product for comforting the crease-resistant effect of stricture of vagina, it is characterised in that also including acetyl
One or more in base hexapeptide -8, plant sterol, artemia extract or yeast fermented product extract.
3. it is according to claim 2 with the composite skin care product for comforting the crease-resistant effect of stricture of vagina, it is characterised in that the north African snow
The mass ratio of Cortex Pini Massonianae extract, Sargassum seed extract, astaxanthin and yeast fermented product extract is 0.2-5：0.1-5：0.01-
0.5：0.5-1.
4. it is according to claim 3 with the cosmetic composition for comforting the crease-resistant effect of stricture of vagina, it is characterised in that the north African snow
The mass ratio of Cortex Pini Massonianae extract, Sargassum seed extract, astaxanthin and yeast fermented product extract is 1.2：1.5：0.2：0.8.
5. having in preparation with the composite skin care product for comforting the crease-resistant effect of stricture of vagina any one of Claims 1-4 comforts stricture of vagina
Application in the skin care item or cosmetics of crease-resistant effect.
6. it is a kind of with the eye cream for comforting the crease-resistant effect of stricture of vagina, it is characterised in that the skin protection by any one of Claims 1-4
In product compositionss and eye cream, acceptable adjuvant is prepared from.
7. the eye cream for comforting the crease-resistant effect of stricture of vagina stated according to claim 6, it is characterised in that by the raw material system of following mass percent
It is standby to form：Composite skin care product 0.8%-8%, plant source wedding agent 2%-5% described in any one of Claims 1-4, antioxygen
The deionized water of agent 0.1%-3%, wetting agent 1%-5%, thickening agent 0.2%-1%, vegetable oil 5%-10% and surplus.
8. the eye cream of the crease-resistant effect of stricture of vagina is comforted as claimed in claim 7, it is characterised in that the plant source wedding agent is selected from lecithin
One or more in fat, alkyl androstanediol, inulin ester or citrate；
One or more in sodium polyacrylate, xanthan gum, hydroxyethyl cellulose or methylcellulose of the thickening agent；
The vegetable oil is selected from Jojoba oil, Semen pruni armeniacae oil, olive oil, camellia seed oil, Semen Tritici aestivi germ oil, safflower oil, Fructus Vitis viniferae
One or more in seed oil or white Limnanthes Alba Seed Oil；
The antioxidant in tocopherol, Ubidecarenone, beta-carotene, lycopene, tea polyphenols or vitamin C one
Plant or various；
The wetting agent selected from hyaluronate sodium, pyrrolidone sodium carboxylate, ceramide, Sargassum extract, amino acid humectant,
One or more in glycerol caprylate or 1,2- hexanediol.
9. the eye cream of the crease-resistant effect of stricture of vagina is comforted as claimed in claim 8, it is characterised in that the plant source wedding agent is selected from Semen sojae atricolor
The mixture of lecithin, cetearyl glucoside and inulin lauryl carbamate：The vegetable oil selected from Jojoba oil,
Safflower oil and the mixture of white Limnanthes Alba Seed Oil；Mixing of the antioxidant selected from Ubidecarenone, lycopene and tea polyphenols
Thing；Mixture of the wetting agent selected from hyaluronate sodium, ceramide, glycerol caprylate and 1,2- hexanediol；The thickening
Agent is selected from the mixture of sodium polyacrylate and xanthan gum.
10. the preparation method with the eye cream for comforting the crease-resistant effect of stricture of vagina any one of claim 6 to 9, it is characterised in that
By the composite skin care product and adjuvant described in any one of Claims 1-4 blended stirring system breast, obtain final product.
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| CN107496245A (en) * | 2017-09-15 | 2017-12-22 | 澳宝化妆品（惠州）有限公司 | A kind of anti-aging liposome composition and its preparation method and application |
| CN107496245B (en) * | 2017-09-15 | 2020-04-03 | 澳宝化妆品（惠州）有限公司 | Anti-aging liposome composition and preparation method and application thereof |
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