CN108618987A - A kind of external preparation of skin nursing and preparation method thereof - Google Patents

A kind of external preparation of skin nursing and preparation method thereof Download PDF

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Publication number
CN108618987A
CN108618987A CN201710861602.XA CN201710861602A CN108618987A CN 108618987 A CN108618987 A CN 108618987A CN 201710861602 A CN201710861602 A CN 201710861602A CN 108618987 A CN108618987 A CN 108618987A
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oil
skin
extract
external preparation
purified water
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吴继群
张嘉恒
丰彬
刘婷婷
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Beijing Yu Mei Biotechnology Co Ltd
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Beijing Yu Mei Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers

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Abstract

The invention discloses a kind of external preparations of skin nursing, include the component of following weight percent (%):Astaxanthin:0.2‑1.0;Orange peel glucoside extract:0.2‑2.0;Lactoprotein:0.5‑3.0;Extractive of perilla:0.2‑2.0;Resveratrol:0.5‑3.0;Leonurus extract:0.2‑3.0;Pepper seed extract:0.2‑2.0;Walnut oil:2.0‑10.0;Purple Perilla Seed Oil:2.0‑10.0;Lavender oil:2.0‑10.0;Sodium Hyaluronate:0.2‑3.0;Ginger oil:0.2‑2.0;Serine:0.5‑3.0;Borneol (kapur):0.05‑0.5;6 polyglycereol of olive oil PEG, 6 esters:2.0‑10.0;Purified water:35.5‑89.05.Preparation method is further related to, prepares water phase components and oil phase components respectively, two components are mixed, emulsification obtains the external preparation.The external preparation of the skin nursing of the present invention uses natural component, can carry out profound reparation and nursing to being damaged skin, have the effect of skin whitening, anti-oxidant, moist, moisturizing, antiallergy, enhancing cutaneous immunisation power.

Description

A kind of external preparation of skin nursing and preparation method thereof
Technical field
The present invention relates to skin care fields more particularly to a kind of external preparation of skin nursing and preparation method thereof.
Background technology
Modern city air pollution is increasingly severe, and many people live under busy, high pressure and formed many undesirable lifes Custom living, it is often edible to contain the food of more chemical addition agent, and be chronically exposed under various radiation plus skin, this is just So that skin virtually by certain damage, is being susceptible to a series of diseases such as allergy, the colour of skin are obscure, aging is accelerated Shape.The appearance of anti-oxidant skin preparations for extenal use can be good at solving the problems, such as that the above skin occurs various, it is not only able to prevent The too fast oxidation of skin, aging, can also repair and profound nursing is damaged skin, skin preparations for extenal use it is included it is anti-oxidant because Son can be good at preventing the too fast oxidation of skin, delaying skin aging, skin whitening, moisturizing skin so that skin rich in gloss and Elasticity allows people to radiate the vigour of youth, and increases happiness to people’s lives.
But skin preparations for extenal use currently on the market, always will appear in various degree, variety classes the problem of, outside skin With agent because being all made of synthesis Antioxidative Factors, causes inoxidizability unstable, be used for a long time, cannot not only play reparation and protection The purpose of skin can also so that skin becomes intense darkness without light, skin becomes more stiff, to extraneous stimulation more insensitiveness;Or Person, it is inadequate containing more artificial synthesized chemical addition agent and oxidation resistance, there is different degrees of stimulation to skin, this is just So that skin becomes more sensitive, and the cuticula of skin is easy by different degrees of destruction, and skin own situation is further Deteriorate, the not oxidized purpose of protection skin is not achieved.Therefore, a kind of pure natural external preparation for skin with superpower oxidation resistance The appearance of agent becomes active demand of the people to skin care.
Natural astaxanthin (natural astacin) is one of strongest natural in the world, can be effectively in scavenger-cell Oxygen radical, enhance cytothesis ability, maintain organism balance and reduce senile cell accumulation, protect cell from inside to outside Hair growth, anti-aging is promoted to alleviate sports fatigue, invigorate to protect skin health with DNA health.From 2008 Since, domestic and international numerous studies confirm that astaxanthin has stronger antioxidant activity, are improving immunity, pre- preventing tumor, painstaking effort The occurrence and development of the chronic diseases such as pipe disease, diabetes, slow down aging etc. have positive facilitation.
According to the strong oxidizing property of astaxanthin, astaxanthin is mainly used for medical effect, as antibacterial, anti-inflammatory, medicines and health protection and Food, field of beverage, for skin nursing products first to there are blank.
Invention content
In conjunction with the deficiency of existing product technology, the present invention provides a kind of external preparation of skin nursing and preparation method thereof, Solve the problems, such as unstable existing external preparation inoxidizability and stimulation, damage skin.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of external preparation of skin nursing, the external preparation include the component of following weight percent (%):
Astaxanthin:0.2-1.0;Orange peel glucoside extract:0.2-2.0;Lactoprotein:0.5-3.0;
Extractive of perilla:0.2-2.0;Resveratrol:0.5-3.0;Leonurus extract:0.2-3.0:
Pepper seed extract:0.2-2.0;Walnut oil:2.0-10.0;Purple Perilla Seed Oil:2.0-10.0;
Lavender oil:2.0-10.0;Sodium Hyaluronate:0.2-3.0;Ginger oil:0.2-2.0;
Serine:0.5-3.0;Borneol (kapur):0.05-0.5;
- 6 esters of olive oil PEG-6 polyglycereol:2.0-10.0;Purified water:35.5-89.05;
The sum of the above components weight percent is 100%.
Further, the external preparation includes the component of following weight percent (%):
Astaxanthin:0.5-0.8;Orange peel glucoside extract:0.5-1.0;Lactoprotein:1.0-2.0;
Extractive of perilla:0.5-1.0;Resveratrol:1.0-2.0;Leonurus extract:1.0-2.0;
Pepper seed extract:0.5-1.0;Walnut oil:5.0-8.0;Purple Perilla Seed Oil:5.0-8.0;
Lavender oil:5.0-8.0;Sodium Hyaluronate:0.5-1.5;Ginger oil:0.5-1.0;
Serine:1.0-2.0;Borneol (kapur):0.2-0.4;
- 6 esters of olive oil PEG-6 polyglycereol:5.0-8.0;Purified water:70.0-80.0;
The sum of the above components weight percent is 100%.
Further, the external preparation includes the component of following weight percent (%):
Astaxanthin:0.5;Orange peel glucoside extract:0.5;Lactoprotein:1.0;
Extractive of perilla:0.5;Resveratrol:1.0;Leonurus extract:1.0;
Pepper seed extract:0.5;Walnut oil:2.0;Purple Perilla Seed Oil:5.0;
Lavender oil:5.0;Sodium Hyaluronate:0.5;Ginger oil:1.0;
Serine:1.0;Borneol (kapur):0.5;
- 6 esters of olive oil PEG-6 polyglycereol:2.0;Purified water:78.0;
The sum of the above components weight percent is 100%.
A kind of preparation method of the external preparation of skin nursing, includes the following steps
Step 1:Water phase components are prepared, purified water is divided into I groups purified water and II group purified waters, by I groups purified water, shrimp Green element, lactoprotein, serine, Leonurus extract weigh by weight percentage, and 30-50 DEG C is heated in closed container, turn Speed is stood after being mixed 30 minutes under 500-1000rad/ minutes;
Step 2:Oil phase component is prepared, respectively by Purple Perilla Seed Oil, walnut oil, lavender oil, olive oil PEG-6 polyglycereol- 6 esters and ginger oil weigh by weight percentage matches, and 30-50 DEG C is heated in closed container, rotating speed is in 1000-1500rad/ It is mixed 30 minutes under minute;
Step 3:The oil phase component after mixing is heated to 50-80 DEG C, is added to where the water phase components Mixer in, and by the extractive of perilla after weighing, pepper seed extract, orange peel glucoside extract, resveratrol, hyaluronic acid Sodium and borneol are added in mixture, are gradually cooling to room temperature, in cooling process with 1000-3000rad/ minutes rotating speeds into Row stirring and emulsifying 30-60 minutes, after II group purified waters are added in mixed liquor emulsify it is uniform.
Further, the ratio of the I groups purified water and II group purified waters is 2: 3.
The beneficial effects of the invention are as follows:
1, the present invention utilizes the strong oxidizing property of astaxanthin, and the oxidation for preventing skin too fast profoundly, aging, crumple are right Impaired skin carries out profound reparation and nursing, has skin whitening, anti-oxidant, moist, moisturizing, antiallergy, enhancing skin Immunity;
2, the present invention using astaxanthin as Strong oxdiative base while, using oxidant orange peel glucoside extract as tie, It can preferably be blended with other natural components, and then preferably reach skin whitening, anti-oxidant and enhancing cutaneous immunisation power Effect;
3, skin preparations for extenal use of the invention reaches skin whitening after while can play moisturizing, sterilization disappears Inflammation calms, goes to wrinkle and prevent allergy and enhance the effect of the immunity of skin, and after long-time service, skin, which becomes smooth, bullet Property, it is nontoxic to skin, have no stimulation, it because of malaise symptoms such as its allergy, will not more be suitble to the crowd of various skin quality to use, sexual valence Than high, environmentally protective;
4, skin preparations for extenal use of the invention is prepared separately using component during preparation, carries out specific environment later Emulsification, natural materials can be effectively kept, as extractive of perilla, pepper seed extract, orange peel glucoside extract, resveratrol, The loss or part composition structural damage of the medicinal ingredient of Sodium Hyaluronate and borneol itself, to ensure product component Effect maximizes.
Description of the drawings
Fig. 1 is the structural schematic diagram of ultraviolet light comparison skin effect.
Specific implementation mode
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented The component of example can be arranged and be designed with a variety of different configurations.Therefore, below to the reality of the present invention provided in the accompanying drawings The detailed description for applying example is not intended to limit the range of claimed invention, is merely representative of the selected embodiment of the present invention, Instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creative labor The every other embodiment obtained under the premise of dynamic, shall fall within the protection scope of the present invention.
Embodiment 1:
A kind of external preparation of skin nursing comprising the component of following weight percent (%):
Astaxanthin:0.5;Orange peel glucoside extract:0.5;Lactoprotein:1.0;
Extractive of perilla:0.5;Resveratrol:1.0;Leonurus extract:1.0;
Pepper seed extract:0.5;Walnut oil:2.0;Purple Perilla Seed Oil:5.0;
Lavender oil:5.0;Sodium Hyaluronate:0.5;Ginger oil:1.0;
Serine:1.0;Borneol (kapur):0.5;
- 6 esters of olive oil PEG-6 polyglycereol:2.0;Purified water:78.0.
Embodiment 2:
A kind of external preparation of skin nursing comprising the component of following weight percent (%):
Astaxanthin:0.2;Orange peel glucoside extract:0.2;Lactoprotein:0.5;
Extractive of perilla:1.0;Resveratrol:0.5;Leonurus extract:0.2;
Pepper seed extract:0.2;Walnut oil:5.0;Purple Perilla Seed Oil:2.0;
Lavender oil:2.0;Sodium Hyaluronate:0.2;Ginger oil:0.2;
Serine:0.5;Borneol (kapur):0.05;
- 6 esters of olive oil PEG-6 polyglycereol:5.0;Purified water:82.25.
Embodiment 3:
A kind of external preparation of skin nursing comprising the component of following weight percent (%):
Astaxanthin:0.5;Orange peel glucoside extract:1.0;Lactoprotein:2.0;
Extractive of perilla:0.2;Resveratrol:2.0;Leonurus extract:2.0;
Pepper seed extract:1.0;Walnut oil:8.0;Purple Perilla Seed Oil:8.0;
Lavender oil:8.0;Sodium Hyaluronate:1.5;Ginger oil:0.5;
Serine:2.0;Borneol (kapur):0.2;
- 6 esters of olive oil PEG-6 polyglycereol:8.0;Purified water:55.1.
Embodiment 4:
A kind of external preparation of skin nursing comprising the component of following weight percent (%):
Astaxanthin:1.0;Orange peel glucoside extract:2.0;Lactoprotein:3.0;
Extractive of perilla:2.0;Resveratrol:3.0;Leonurus extract:3.0;
Pepper seed extract:2.0;Walnut oil:10.0;Purple Perilla Seed Oil:10.0;
Lavender oil:10.0;Sodium Hyaluronate:3.0;Ginger oil:2.0;
Serine:3.0;Borneol (kapur):0.4;
- 6 esters of olive oil PEG-6 polyglycereol:10.0;Purified water:35.6.
Wherein, astaxanthin is divided at following 4 points to the specific effect of skin, as shown in Figure 1:
(1) crease-resistant effect:Skin is made of three-decker:Epidermis, skin corium, subcutaneous tissue.Skin corium contains Collagen, elastin and other fibers constitute the skeleton of support skin.And these elements make skin seem smooth Youth, these same elements are also vulnerable to the damage of long wave ultraviolet (UVA) and short wavelength UV (UVB).This long waves of wherein UVA are purple Outside line can reach skin corium, main damage collagen and elastin laminin, and the skeleton of epidermis is supported to disappear, and cause epidermis different Degree collapses, and skin forms wrinkle;Short wavelength UV (UVB) then mainly acts on epidermis, leads to the heavy of sunburn or melanin Product forms spot or skin darkening.Ultraviolet light itself can promote the active oxygen and matrix metalloproteinase in situ that skin generates, this A little factors are the roots that wrinkle generates, because they have destroyed the collagen matrices of skin corium.Fortunately skin itself Repair mechanism is the collagen that can rebuild damage, however, if active oxygen (ROS) and matrix metalloproteinase (NMP) Destructive activity cannot effectively control, they will continue to damage these collagens, thus seriously hinder skin from The reparation process of body, astaxanthin can then be obviously reduced active oxygen (ROS) and matrix metalloproteinase (NMP) to skin corium collagen The destruction of albumen, elastin ensure that the eubolism of skin.
(2) anti-sunlight function:Astaxanthin has its unique molecular structure, and the absorption peak of substance is exactly 470nm or so, with The close therefore micro astaxanthin of long wave ultraviolet (UVA) wavelength (380-420nm) can absorb a large amount of UVA, can be efficient UV-induced free radical is quenched in ground ultraviolet radiation preventing, the sunburn for avoiding or mitigating ultraviolet light to skin, effectively prevents purple The degeneration of skin collagen matter, the formation of wrinkle and blackspot of outside line induction.In addition to this, it also can rapidly be restored by ultraviolet light The skin that burn is destroyed.
(3) freckle removing and whitening acts on:The generation that astaxanthin can effectively inhibit melanin is up to 40%, and can substantially reduce The precipitation of melanin.
(4) anti-aging effect:Skin is made of epidermis, skin corium, subcutaneous fat.Skin corium contains collagen egg In vain, elastin and other fibers constitute the skeleton of support skin.And these elements make skin seem smooth youth, together These elements of sample are also vulnerable to the damage of (UVA), short wavelength UV (UVB) and ozone or other oxidative factors.When skin corium After collagen is because above-mentioned a variety of causes aoxidized, is broken, the supporting role of epidermis is just disappeared, therefore cause epidermis It can collapse inhomogenously, such wrinkle just produces, and skin will become dimness, relaxation, drying and microgroove, crow's feet occurs Equal wrinkles.And astaxanthin can efficiently remove free radical, protection Skin Cell is injury-free, and collagen is prevented to decompose, to Keep cell state full, it is dynamic, restore skin-lifting, and the skin of recess is repaired again.
Orange peel glucoside extract:A kind of natural antioxidant has and maintains osmotic pressure, enhances capillary toughness, shortens Bleeding time, reduce cholesterol the effects that, contained by tartaric acid substance, have whitening, absolute oil, softness, tender skin the effect of.
Lactoprotein:A kind of skin conditioning agent has following effect to skin:(1) moist keratoderma is may expand, is made Pore is expanded, and facial blood circulation, absorption of the enhancing skin to nutriment and bioactie agent are promoted;(2) in lactoprotein Whole essential amino acids containing needed by human body and other amino acid are complete protein, are human skin, muscle, hair, blood The main constituents of the tissues such as slurry;(3) iron contained in lactoprotein can enhance hematopoiesis function, and skin is from sufficient blood It obtains required nutrition and moistens, fur also therefore can normal growth;(4) vitamin b2 contained in lactoprotein can be maintained The normal update of metabolic vigorous epithelial cell, can prevent face seborrhea, the bran scales of skin that peel off and dry skin, scabies Itch;(5) niacin contained in lactoprotein can prevent the pachylosis caused by solar dermatitis, thicken;(6) contained in lactoprotein Pantothenic acid, play the role of promoting hair regeneration, prevent from itching and alopecia, and with preventing pachylosis, eliminate fine wrinkles Effect;(7) lysozyme contained in lactoprotein, can prevent herpes zoster, flat wart, and contained sterol has well skin Permeability can keep the moisture of skin surface, promote skin metabolism, inhibit scytitis, prevent sunburn and skin Skin aging.
Extractive of perilla:Purple perilla, Labiatae annual herb plant have special fragrance.Containing rich in its extract Rich vitamin C, potassium, iron etc., also contains abundant unsaturated fatty acid, has the function of that immune function is made normally to play, have Mitigate the anaphylactoid effects such as allergic dermatitis, pollinosis;Purple perilla can be additionally used in treating for skin disease, and perilla herb oil is to natural dirt The mould of dye has apparent restraint, and nipalgin acetic acid is substantially better than to the restraint of mould, and few, safe with dosage, The characteristics of not influenced by pH value factor.
Resveratrol:A kind of biological very strong polyphenols, can improve photoaging skin polyphenoils enzymatic activity, Change oxidation product content, reaches anti-skin photoage effect.
Leonurus extract:Containing various trace elements such as selenium, manganese etc., there is promoting blood circulation and removing blood stasis, enhancing skin cutaneous immunisation Power slows down skin aging, and anti-oxidant, aging and inhibition cancer cell generate, and can effectively remove face's grease, sterilizing, light Sliding skin has certain effect to treatment dark sore.
Pepper seed extract:Blood circulation can be stimulated, skin dead cell is removed, skin surface is made to obtain more oxygen Gas and nutrients.
Walnut oil:Rich in the spiny dogfish splendid with skin affinity and essential aliphatic acid for human body, can rapidly by percutaneous absorption, It effectively keeps skin elasticity and moistens, facial wrinkles can be eliminated, prevent skin aging, have the function of moisturizing the skin.
Purple Perilla Seed Oil:The vigor that superoxide dismutase in red blood cell (SOD) can be significantly improved, to delay body aging and Bodybuilding skin has apparent effect.
Lavender:It is as follows to the effect of skin:(1) water and oil balance is adjusted, skin overdrying is excessively oily, is all due to surface layer Caused by water oil imbalance, lavender deep layer adjusts skin ph value, and control table musculus cutaneus skin fat secretion utilizes the superpower benefit of cypress Water moisturizing ingredient restores the optimum state of skin water and oil balance;(2) prevent pore coarse, the dirt resistance in deep layer unclogging Plug, compact epidermis skin, restrains pore, inhibits epidermis grease excessive secretion, and it is coarse to prevent from being formed pore again, promotes cell again It is raw, improve obscure dry aged skin;(3) whelk is treated, Provencal first-class lavender adds with Australia tea tree, has pole Strong bactericidal antiphlogistic effect quickly enters hair follicle and removes small pox bacterium, eliminates epidermis whelk, acne, acne etc., repairs impaired thin Born of the same parents promote cytothesis;(4) scar, Lavender itself is gone to be good scar healing, it being capable of scar desalination pigment Deposition;(5) pore cleanser, it is object, lavender essence that blackhead, which is by being formed by black " bolt " in follicular orifice caused by hair follicle blocking, Oil can deep layer conditioning essential oil quickly enter hair follicle, remove deposit in hair follicle, dredging pore removes excess oil.
Sodium Hyaluronate:With powerful water absorbing capacity and moisture-keeping functions, unique protection skin can be played the role of, can be grown Moisten skin, keep skin smooth, exquisiteness, tender, high resilience, keep the moisture of skin, hair, moisturize the skin, hair, increases Gloss, and the generation of chapped skin and wrinkle can be prevented, with wrinkle resistant, crease-resistant, beauty and health care and restore skin physiology function Effect.
The extract of race:It contains gingerol, can adsorb superfluous grease and keep skin salubrious, in addition ginger oil contains There are many active constituents, can repair acne hole acne print, lighten the stain, improve coarse skin surface.Why ginger can desalinate face The color spot in portion is can to accelerate the aging of skin because of internal free radical, and the gingerol in ginger can weaken free radical, from And play the role of lightening the stain.
Serine:Because its small molecule structure is easy to, by percutaneous absorption, be more easy to play a role, to the main work of skin With as follows:(1) it can be damaged cutin by repairing, enables cuticula conserve more juicy, to help moisturizing, is helped by moisturizing It is fuel-displaced fierce to improve skin.It is fuel-displaced to have lacked skin to be not easy oil extraction naturally unsmooth and red and swollen emit acne;(2) repair of skin collagen peptide bond and Its spiral net-shaped structure is remolded in the fracture of elasticated net, and it is green to reverse aging phenomenons, the recovery of Q bullets such as original drying is wrinkled more, relaxation collapses Spring flesh;(3) the pit-hole damage of repair of skin, helps skin to resist free radical, prevents aging.
Borneol (kapur):It is to be laid equal stress on knot through steam distillation by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves It is brilliant and obtain, it is a kind of crystal of volatile oil containing there are many terpenoids, with clearly refreshing oneself and increase skin care item fragrance Effect.
- 6 esters of olive oil PEG-6 polyglycereol:As a kind of emulsifier, since its unique molecular structure (contains one end Lipophilic group is contained in hydrophilic radical, one end) so that it can be good at oil phase is mixed with water uniformly, and it can be with Dirt in pore is removed, nourishes rough skin increases the volume gloss and elasticity of skin, eliminates and wrinkle is delayed to occur, it is old to slow down skin Change, anticracking is antipruritic.
A kind of preparation method of the external preparation of skin nursing, includes the following steps:
Step 1:Water phase components are prepared, purified water is divided into I groups purified water and II group purified waters, by I groups purified water, shrimp Green element, lactoprotein, serine, Leonurus extract weigh by weight percentage, and 30-50 DEG C is heated in closed container, turn Speed is stood after being mixed 30 minutes under 500-1000rad/ minutes;
Wherein, the ratio of I groups purified water and II group purified waters is 2: 3.
Step 2:Oil phase component is prepared, respectively by Purple Perilla Seed Oil, walnut oil, lavender oil, olive oil PEG-6 polyglycereol- 6 esters and ginger oil weigh by weight percentage matches, and 30-50 DEG C is heated in closed container, rotating speed is in 1000-1500rad/ It is mixed 30 minutes under minute;
Step 3:The oil phase component after mixing is heated to 50-80 DEG C, is added to where the water phase components Mixer in, and by the extractive of perilla after weighing, pepper seed extract, orange peel glucoside extract, resveratrol, hyaluronic acid Sodium and borneol are added in mixture, are gradually cooling to room temperature, in cooling process with 1000-3000rad/ minutes rotating speeds into Row stirring and emulsifying 30-60 minutes, after II group purified waters be added in mixed liquor emulsify uniform, the external application of final obtained skin nursing Agent.
Finally it should be noted that:Above-described embodiments are merely to illustrate the technical scheme, rather than to it Limitation;Although the present invention is described in detail referring to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: It can still modify to the technical solution recorded in previous embodiment, or to which part or all technical features into Row equivalent replacement;And these modifications or substitutions, it does not separate the essence of the corresponding technical solution various embodiments of the present invention technical side The range of case.

Claims (5)

1. a kind of external preparation of skin nursing, it is characterised in that:The external preparation includes the component of following weight percent (%):
Astaxanthin:0.2-1.0;Orange peel glucoside extract:0.2-2.0;Lactoprotein:0.5-3.0;
Extractive of perilla:0.2-2.0;Resveratrol:0.5-3.0;Leonurus extract:0.2-3.0;
Pepper seed extract:0.2-2.0;Walnut oil:2.0-10.0;Purple Perilla Seed Oil:2.0-10.0;
Lavender oil:2.0-10.0;Sodium Hyaluronate:0.2-3.0;Ginger oil:0.2-2.0;
Serine:0.5-3.0;Borneol:0.05-0.5;
- 6 esters of olive oil PEG-6 polyglycereol:2.0-10.0;Purified water:35.5-89.05;
The sum of the above components weight percent is 100%.
2. the external preparation of skin nursing as described in claim 1, it is characterised in that:The external preparation includes following weight percent The component of (%):
Astaxanthin:0.5-0.8;Orange peel glucoside extract:0.5-1.0;Lactoprotein:1.0-2.0;
Extractive of perilla:0.5-1.0;Resveratrol:1.0-2.0;Leonurus extract:1.0-2.0;
Pepper seed extract:0.5-1.0;Walnut oil:5.0-8.0;Purple Perilla Seed Oil:5.0-8.0;
Lavender oil:5.0-8.0;Sodium Hyaluronate:0.5-1.5;Ginger oil:0.5-1.0;
Serine:1.0-2.0;Borneol:0.2-0.4;
- 6 esters of olive oil PEG-6 polyglycereol:5.0-8.0;Purified water:70.0-80.0;
The sum of the above components weight percent is 100%.
3. the external preparation of skin nursing as described in claim 1, it is characterised in that:The external preparation includes following weight percent The component of (%):
Astaxanthin:0.5;Orange peel glucoside extract:0.5;Lactoprotein:1.0;
Extractive of perilla:0.5;Resveratrol:1.0;Leonurus extract:1.0;
Pepper seed extract:0.5;Walnut oil:2.0;Purple Perilla Seed Oil:5.0;
Lavender oil:5.0;Sodium Hyaluronate:0.5;Ginger oil:1.0;
Serine:1.0;Borneol:0.5;
- 6 esters of olive oil PEG-6 polyglycereol:2.0;Purified water:78.0.
4. the preparation method of the external preparation of skin nursing as described in any one of claim 1-3, it is characterised in that:Including with Lower step,
Step 1:Prepare water phase components, purified water be divided into I groups purified water and II group purified waters, by I groups purified water, astaxanthin, Lactoprotein, serine, Leonurus extract weigh by weight percentage, 30-50 DEG C are heated in closed container, rotating speed exists Lower mixing in 500-1000rad/ minutes is stood after 30 minutes;
Step 2:Oil phase component is prepared, respectively by Purple Perilla Seed Oil, walnut oil, lavender oil, -6 ester of olive oil PEG-6 polyglycereol Class and ginger oil weigh by weight percentage matches, and 30-50 DEG C is heated in closed container, rotating speed is at 1000-1500rad/ points It is mixed 30 minutes under clock;
Step 3:The oil phase component after mixing is heated to 50-80 DEG C, is added to mixed where the water phase components In clutch, and by the extractive of perilla after weighing, pepper seed extract, orange peel glucoside extract, resveratrol, Sodium Hyaluronate and Borneol is added in mixture, is gradually cooling to room temperature, is stirred with 1000-3000rad/ minutes rotating speeds in cooling process Mix emulsification 30-60 minute, after will II group purified waters be added mixed liquor in emulsification uniformly.
5. preparation method as claimed in claim 4, it is characterised in that:The ratio of the I groups purified water and II group purified waters is 2 ∶3。
CN201710861602.XA 2017-09-21 2017-09-21 A kind of external preparation of skin nursing and preparation method thereof Pending CN108618987A (en)

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CN109172491A (en) * 2018-11-22 2019-01-11 赛杜恳医药生物科技(上海)有限公司 A kind of creme and preparation method thereof with anti-aging and activating microcirculation and removing stasis medicinal function
CN109172492A (en) * 2018-11-22 2019-01-11 赛杜恳医药生物科技(上海)有限公司 A kind of fast more frost and preparation method thereof
CN109464348A (en) * 2018-11-22 2019-03-15 赛杜恳医药生物科技(上海)有限公司 A kind of creme and preparation method thereof with beauty and improvement subhealth symptom
CN111568780A (en) * 2020-05-09 2020-08-25 广东华辰凯太健康管理有限公司 Herbal gel with myotonin and preparation method thereof
CN115317429A (en) * 2022-08-30 2022-11-11 马应龙大健康有限公司 Composition containing recombinant collagen and having repairing and relieving effects, eye cream containing composition, preparation method and application
CN115350260A (en) * 2022-09-05 2022-11-18 东莞市容大生物科技有限公司 Daily care biological agent with sleep-aiding function for skin and preparation method thereof

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109172491A (en) * 2018-11-22 2019-01-11 赛杜恳医药生物科技(上海)有限公司 A kind of creme and preparation method thereof with anti-aging and activating microcirculation and removing stasis medicinal function
CN109172492A (en) * 2018-11-22 2019-01-11 赛杜恳医药生物科技(上海)有限公司 A kind of fast more frost and preparation method thereof
CN109464348A (en) * 2018-11-22 2019-03-15 赛杜恳医药生物科技(上海)有限公司 A kind of creme and preparation method thereof with beauty and improvement subhealth symptom
CN111568780A (en) * 2020-05-09 2020-08-25 广东华辰凯太健康管理有限公司 Herbal gel with myotonin and preparation method thereof
CN115317429A (en) * 2022-08-30 2022-11-11 马应龙大健康有限公司 Composition containing recombinant collagen and having repairing and relieving effects, eye cream containing composition, preparation method and application
CN115317429B (en) * 2022-08-30 2023-05-26 马应龙大健康有限公司 Composition containing recombinant collagen and having repairing and relieving effects, eye cream containing composition, preparation method and application
CN115350260A (en) * 2022-09-05 2022-11-18 东莞市容大生物科技有限公司 Daily care biological agent with sleep-aiding function for skin and preparation method thereof
CN115350260B (en) * 2022-09-05 2024-02-23 东莞市容大生物科技有限公司 Daily care biological agent with sleep-aiding function for skin and preparation method thereof

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Application publication date: 20181009