CN109464348A - A kind of creme and preparation method thereof with beauty and improvement subhealth symptom - Google Patents

A kind of creme and preparation method thereof with beauty and improvement subhealth symptom Download PDF

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Publication number
CN109464348A
CN109464348A CN201811401251.5A CN201811401251A CN109464348A CN 109464348 A CN109464348 A CN 109464348A CN 201811401251 A CN201811401251 A CN 201811401251A CN 109464348 A CN109464348 A CN 109464348A
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parts
extract
creme
oil
titanium dioxide
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叶文远
邹方
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Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd
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Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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Abstract

The invention discloses a kind of with beauty and improves the creme and preparation method thereof of subhealth symptom, the creme is with brown alga extract and porous nano titanium dioxide microballoon sphere, India's poponax resin extract, creatine and the atriphos of grey green soy bean seed extract cladding for main activated feedstock, the nutriments such as lactoprotein and serine are added, there is the substance of clearing and activating the channels and collaterals in conjunction with various naturals and motherwort and borneol etc., so that it is played more preferable effect by scientific selection and reasonably combined be organically combined together various natural nutrient substances.Creme provided by the present invention can be absorbed by skin, be boosted metabolism and cell repair, keep skin smooth fine and smooth to reach cosmetic result.In addition, creme provided by the present invention can also balanced human's endocrine, stimulation blood of human body circulates, and increases itself secreting hormone, fundamentally improves body immunity low, anxiety, agitation, insomnia and the inferior health problems such as deficient in energy.

Description

A kind of creme and preparation method thereof with beauty and improvement subhealth symptom
Technical field
The present invention relates to beauty skin care products, and in particular to it is a kind of with beauty and improve subhealth symptom creme and its Preparation method.
Background technique
As being constantly progressive for society is made with economic sustainable development, the variation of weather and environment to the living environment of the mankind At in increasingly severe pollution, especially air various pollutants matter and various harmful emitting electromagnetic radiations can induce Human body generates free radicals and other harmful organism active materials so as to cause human senility or even cause various diseases.This is because Biological damage can be caused to human body during generating free radicals, is exactly intuitively most that human skin can generate various forms Change and condition, such as dry, nigrescence, coarse and relaxation etc..In addition, plus the study of modern, work and life work It is excessive be easy to cause body endocrine disorder and metabolic disorder so that cause skin wrinkle, the colour of skin it is uneven, it is coarse, lack Elasticity, the gloomy jaundice of the colour of skin, color spot freckle, drying and the inferior health problems such as pore is coarse.
Common people can select cosmetics or Orally taken health article etc. to reduce or postpone the generation of the above symptom, but external application only Health care product is fewer and fewer.For common skin care item based on moisturizing moisturizing, primary raw material is with moisture-keeping functions currently on the market Various oil compounds, its moisture-keeping functions compare shallow-layer to brought by skin change be also it is of short duration, do not have skin Skin cures the problem of function can not fundamentally improve skin aging, with less other healthcare functions.Though Orally taken health article So there is healthcare function, but work slow and be not too ideal to the improvement of skin aging.
With the continuous improvement of people's living standards, requirement of the people to beauty and skin care cosmetics is also higher and higher, in day So, nutrition, in the upsurge to go back to nature, people increasingly tend to use natural health-care products.Therefore, various natural materials are utilized Radiation-resisting functional, anti-oxidizing activities and cell repair function come develop with antioxygen chemoprevention skin aging and promote skin it is thin The creme with beauty and improvement subhealth symptom that born of the same parents are metabolized and quickly repair is significantly.
Summary of the invention
It is an object of the invention to solve the disadvantage that existing external application moisturizing product, provide it is a kind of have it is anti-oxidant, anti-aging and The creme and preparation method thereof with beauty and improvement subhealth symptom of Skin Cell reparation can be rapidly promoted.
In order to achieve the above objectives, solution of the invention is:
A kind of creme with beauty and improvement subhealth symptom, which is characterized in that described that there is beauty and improve sub- be good for The material content of the creme of health symptom is as follows in parts by weight: 1-2 parts of lactoprotein, 1-2 parts of serine, and apple extract 0.5-1.5 parts, 1-2.5 parts of resveratrol, 0.5-1.5 parts of moutan root bark, 0.5-1.5 parts of borneol, Sodium Hyaluronate 0.5-1.5 Part, 0.5-1.5 parts of motherwort, 0.1-0.6 parts of pepper seed extract, 2-5 parts of walnut oil, 1-3 parts of Purple Perilla Seed Oil, 1-2 parts of Asian puccoon, 1-2 parts of lavender oil, 0.5-1.5 parts of oat, 0.5-1.5 parts of aurantiamarin .1-0.5 parts of ginsengenin 20, olive oil PEG-6 esters 5-10 parts, 0.5-1.5 parts of glutathione, 1.2-1.6 parts of ginger oil, 0.5-1.5 parts of astaxanthin, 0.1-0.5 parts of atriphos, 2-5 parts of brown alga extract, 3-7 parts of grey green soy bean seed extract, 0.5-1 parts of creatine, India poponax resin extract 0.02-0.05 Part, 0.02-0.05 parts of rhEGF, 7-12 parts of porous nano titanium dioxide microballoon sphere, 30-65 parts of water.
A kind of preparation method with beauty and the creme for improving subhealth symptom, which is characterized in that specifically include as follows Step:
(1) brown alga extract is dissolved in dehydrated alcohol, porous nano titanium dioxide microballoon sphere is then added, gained mixture exists 45 DEG C of heating stirring 1h, then 50 DEG C of dryings remove solvent for 24 hours and are made that brown alga extract is coated porous receives in a vacuum drying oven Rice titanium dioxide microballoon sphere;
(2) grey green soy bean seed extract is dissolved in dehydrated alcohol, porous nano titanium dioxide microballoon sphere, gained mixing is then added Object is in 45 DEG C of heating stirring 2h, and then 50 DEG C of dryings remove solvent for 24 hours and grey green soy bean seed extract packet is made in a vacuum drying oven Cover porous nano titanium dioxide microballoon sphere;
(3) it is mixed after crushing moutan root bark, borneol, motherwort, Asian puccoon, oat, aesculin and aurantiamarin respectively, mistake Mixed-powder is made in sieve;
(4) serine, resveratrol, Sodium Hyaluronate, atriphos, glutathione and creatine are added to the water and are stirred It mixes and is heated uniformly to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) by lactoprotein, walnut oil, Purple Perilla Seed Oil, ginger oil, lavender oil, olive oil PEG-6 esters, ginsenoside, Astaxanthin and India's poponax resin extract are heated to 80 DEG C and 30 minutes obtained oil mixtures of constant temperature;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified;Emulsification pot temperature is down to 45 DEG C after emulsification, then sequentially adds step (1) In grey green soy bean seed extract cladding obtained in the coated porous nanometer titanium dioxide micro-sphere of brown alga extract obtained and step (2) Porous nano titanium dioxide microballoon sphere, stirs evenly;Then emulsification pot temperature is down to 35 DEG C, mixing obtained in rapid (3) is added Powder stirs evenly;Finally will emulsification pot temperature be down to 30 DEG C, sequentially add apple extract, pepper seed extract and RhEGF, each component discharges after mixing evenly can be prepared by the creme with beauty and improvement subhealth symptom.
Preferably, the average grain diameter of the porous nano titanium dioxide microballoon sphere is 50-90 nanometers.
Preferably, the partial size of step (3) described mixed-powder is 70-100 microns.
Chief active raw material used in the present invention is described in detail below:
The fucoidin contained in brown alga extract is also very comprehensively, in moisturizing antiallergic, to repair to the benefit of skin Skin barrier, anti-oxidant etc. have fine effect.The growing environment of brown alga is more severe, it can secret out of " fucoidin " To protect frond surface --- fucoidin can allow injury of the brown alga not by ultraviolet light and bacterium, and repair injured position Cell.
Grey green soy bean seed extract can adjust the cortisol in Skin Cell and beta-endorphin secretion, activate compressive resistance The expression of gene activates compressive resistance albumen, hence it is evident that improves the colour of skin.
Aesculin has anti-inflammatory, antibacterial, anticoagulant, analgesia isoreactivity, has significant diuresis to mouse.It can inhibit The aldose reductase of rat crystalline lens is the growth inhibitor of hay bacillus, while to chemically also having inhibiting effect to cancer.
Resveratrol is a kind of natural antioxidant, inhibits coagulating platelets and vasodilation, keeps unobstructed blood, tool There are antiatherosclerosis and coronary heart disease, ischemic heart disease, the preventive and therapeutic effect of blood lipid.Have and brings down a fever and analgesic effect, angiocarpy Protective effect promotes immune system activity, free radical resisting, anti-inflammatory, antibacterial, promotes longevity.
Lactoprotein can be such that pore expands, and promote blood circulation, and enhance suction of the skin to nutriment and bioactie agent It receives.
Serine facilitates the generation of immunoglobulin and antibody, in manufacture processing, musculature and the encirclement of cell membrane Effect is all played in the synthesis of the sheath of nerve cell, silk ammonia serine can promote the metabolism of fat and fatty acid, help In maintenance immune system.
The warm-natured heat of pepper seed extract has good relaxation effect, and controls to stomach abdomen crymodynia, borborygmus diarrhea caused by stomach cold Treat anemofrigid cold, can cold dispelling, stomach invigorating etc., can improve a poor appetite, is aid digestion, inspiring sweat;Can also improve women abnormal leucorrhea and Epilepsy.
Purple perilla has relieving exterior syndrome and dispelling cold, and relieving QI stagnancy in the stomach is usually used in treating anemofrigid cold, cough evil of vomitting and fish and crab poisoning etc..
Aurantiamarin is the drug for treating hypertension and myocardial infarction, one of main composition of Chinese patent drug Maitong.Aurantiamarin tool There are lipid peroxidation inhibition, scavenging activated oxygen, anti-inflammatory, antiviral, antibacterial action, long-time service can delay senescence and anticancer.
Borneol has the function of inducing resuscitation of having one's ideas straightened out, clearing heat for detumescence, analgesic etc., can be used for treating divine coma, apoplexy coma due to blocking of the respiratory system, gas It faints, the diseases such as middle evil, sore swell and ache curative, aphtha, abscess of throat, eye illness, swelling and aching of gum.For the treatment of coronary heart diseases and angina pectoris, control It is scorching to treat chronic nasal cavity, can be used for neuralgia and anti-inflammatory.Borneol mucous membrane, subcutaneous tissue bacterium be easy absorb, and in vivo with grape Uronic acid excretes after combining.
Astaxanthin has a variety of physiological functions, such as in inoxidizability, antitumor, pre- anti-cancer, strengthen immunity and improvement Eyesight etc. has certain effect.
Motherwort has treatment menoxenia, vaginal bleeding during pregnancy difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia leakage Under, hematuria, rush down blood, carbuncle swells sore and platelet aggregation, there are also enhance body cellular immunity the effects of, increase coronary artery stream Amount reduces coronary resistance, reducing heart rate and the effect for reducing output quantity and left ventricular work, there is direct excitation.
Ginsenoside has rapid recovery fatigue, delays senescence, is anti-oxidant, accelerating cell repair and skin injury is promoted to be cured The effects of conjunction.
Apple extract vitamin C rich in has effects that toxin-expulsion oxidation-resistance, delaying skin aging, moisturizing and resists Wrinkle effect.
Moutan root bark can inhibit skin free radical to generate, and promote blood circulation, and improve the colour of skin and pore refining and other effects.
Glutathione oxidation resistance with super strength can quickly remove interior free yl, protective inner cell not by oxygen Change damage, anti-aging and antifatigue and anticancer function.
The beta glucan molecule that oat contains has the function of that enhancing immunocompetence improves blood lipid and anti-radiation.
Atriphos and creatine can store and transmit energy for Skin Cell, be the important sources of skin energy, can be with Skin Cell biologos is stimulated, skin ageing is continued, hence it is evident that improves skin quality and the colour of skin.
Sodium Hyaluronate can play unique protective effect to skin, and skin moisturizing can be kept smooth, fine and smooth tender, rich Elasticity has the function of wrinkle resistant, crease-resistant, beauty and health care and restores skin physiology function.
Lavender can be clearing heat and detoxicating, cleaning skin, controls oil, freckle removing and whitening, the tender skin of anti-wrinkle, eye haustra -dsipelling are black Eyelet may additionally facilitate the skin-protecting functions such as regeneration of damaged tissue recovery.
The gingerol and its derivative contained in ginger oil has very strong oxidation resistance, especially very strong to anti-grease The effect of brown element, can substantially reduced senile plaque.
India's poponax resin extract has activating microcirculation and removing stasis medicinal, swelling and pain relieving and inhibition scytitis and other effects.
RhEGF recombinant human epidermal growth factor have with natural hEGF's said function, cell can be promoted Reparation and regeneration, have for the wound repair of the wound repair of skin, cornea tissue, ontogeny and internal organs very heavy The effect wanted.
The principle of the present invention and gain effect are as follows:
(1) the present invention provides a kind of with multi-functional and effect with beauty and improves the creme of subhealth symptom, Organically being combined together above-mentioned natural nutrient substance by the selection and reasonable collocation of science plays it preferably Effect.The creme of tool provided by the present invention is uniformly applied to skin surface, Transdermal absorption is carried out by massage, it can antioxygen Change, boost metabolism and cell repair, improves the smooth exquisiteness of human skin, and then reach anti-aging effects, fundamentally change Kind human skin aging problem.
(2) by it is provided by the present invention with beauty and improve subhealth symptom creme be applied to Dazhui acupoint, tripe flesh and Then the positions such as low back pass through massage progress Transdermal absorption, its energy balanced human's endocrine, stimulation blood of human body circulates, increases certainly Status krinin makes body return back to equilibrium state at an early age, fundamentally improve low body immunity, anxiety, agitation, Insomnia and the inferior health problems such as deficient in energy.
(3) the invention belongs to brown alga extract and grey green soy bean seed extract are creatively loaded to porous nano two for the first time In titania microsphere, the brown alga extract and grey green soy bean seed extract energy that are supported on porous nano titanium dioxide microballoon sphere in this way It is constantly persistently played in having effects that beauty and the creme for improving subhealth symptom, plays the role of sustained release, this is more advantageous to Absorption of the skin to brown alga extract and grey green soy bean seed extract, effectively improves the utilization efficiency of both nutriments. In addition, nano-titanium dioxide itself also has uvioresistant, antibacterial and Bearberry Extract, and nontoxic, tasteless, pollution-free making up It is widely used in product and food.
(4) primary raw material selected by the present invention is natural products, environmentally protective, simple and easy to get.The present invention prepares tool The method for having beauty and improving the creme of subhealth symptom also has many advantages, such as simple and easy, mild condition and easily controllable.
Specific embodiment
Further below in conjunction with the embodiments with the present invention will be described in detail.It will similarly be understood that following embodiment is served only for this Invention is further described, and should not be understood as limiting the scope of the invention, specific quality, reaction time in example With the example that temperature, technological parameter etc. are also only in OK range, those skilled in the art is according to the present invention above-mentioned Some nonessential modifications and adaptations that content is made all belong to the scope of protection of the present invention.
Agents useful for same is not further purified as being commercial reagents without particularly pointing out using preceding.
Embodiment 1:
Preparation step with beauty and the creme for improving subhealth symptom is as follows:
(1) 200g brown alga extract is dissolved in 1.5L dehydrated alcohol, it is 50-90 nanometers that 250g average grain diameter, which is then added, Porous nano titanium dioxide microballoon sphere, gained mixture is in 45 DEG C of heating stirring 1h, then 50 DEG C of dryings in a vacuum drying oven Solvent is removed for 24 hours, and the coated porous nanometer titanium dioxide micro-sphere of brown alga extract is made, it is spare;
(2) 300g ash green soy bean seed extract is dissolved in 2L dehydrated alcohol, 450g average grain diameter is then added and is received for 50-90 The porous nano titanium dioxide microballoon sphere of rice, gained mixture in 45 DEG C of heating stirring 2h, then in a vacuum drying oven 50 DEG C it is dry The coated porous nanometer titanium dioxide micro-sphere of grey green soy bean seed extract is made in the dry solvent that removes for 24 hours;
(3) 50g moutan root bark, 50g borneol, 50g motherwort, 100g Asian puccoon, 50g oat and 50g aurantiamarin difference are weighed It is mixed after crushing, 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, and mixed-powder is made;
(4) by 100g serine, 100g resveratrol, 50g Sodium Hyaluronate, 10g atriphos, 50g glutathione It is added in 3L water to stir evenly with 50g creatine and is heated to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) by 100g lactoprotein, 200g walnut oil, 100g Purple Perilla Seed Oil, 100g lavender oil, 120g ginger oil, 500g Olive oil PEG-6 esters, 10g ginsenoside, 50g astaxanthin and 2g India poponax resin extract are heated to 80 DEG C and constant temperature 30 Minute obtained oil mixture;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 1 hour, and emulsification pot temperature is down to 45 after emulsification DEG C, then sequentially add system in the coated porous nanometer titanium dioxide micro-sphere of brown alga extract obtained in step (1) and step (2) The grey coated porous nanometer titanium dioxide micro-sphere of green soy bean seed extract obtained, stirs evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, 50g apple is sequentially added and mentions Take object, 10g pepper seed extract and 2g rhEGF, each component discharges after mixing evenly can be prepared by described having beauty and improvement The creme of subhealth symptom.
Embodiment 2
(1) 500g brown alga extract is dissolved in 4L dehydrated alcohol, it is 50-90 nanometers that 500g average grain diameter, which is then added, Porous nano titanium dioxide microballoon sphere, gained mixture is in 45 DEG C of heating stirring 3h, then 50 DEG C of dry 48h in a vacuum drying oven It removes solvent and the coated porous nanometer titanium dioxide micro-sphere of brown alga extract is made, it is spare;
(2) 700g ash green soy bean seed extract is dissolved in 7L dehydrated alcohol, 700g average grain diameter is then added and is received for 50-90 The porous nano titanium dioxide microballoon sphere of rice, gained mixture in 45 DEG C of heating stirring 5h, then in a vacuum drying oven 50 DEG C it is dry Dry 48h removes solvent and the coated porous nanometer titanium dioxide micro-sphere of grey green soy bean seed extract is made;
(3) 150g moutan root bark, 150g borneol, 150g motherwort, 200g Asian puccoon, 150g oat, 500g bark of ash first are weighed Element and 150g aurantiamarin mix after crushing respectively, and 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, are made mixed Close powder;
(4) by 200g serine, 250g resveratrol, 150g Sodium Hyaluronate, 50g atriphos, 150g gluathione Peptide and 100g creatine, which are added in 6.5L water to stir evenly, is heated to 75 DEG C and 90 minutes obtained aqueous mixtures of constant temperature;
(5) by 200g lactoprotein, 500g walnut oil, 300g Purple Perilla Seed Oil, 200g lavender oil, 160g ginger oil, 1000g Olive oil PEG-6 esters, 50g ginsenoside, 150g astaxanthin and 5g India poponax resin extract are heated to 80 DEG C and constant temperature 90 minutes obtained oil mixtures;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 3 hours, and emulsification pot temperature is down to 45 after emulsification DEG C, then sequentially add system in the coated porous nanometer titanium dioxide micro-sphere of brown alga extract obtained in step (1) and step (2) The grey coated porous nanometer titanium dioxide micro-sphere of green soy bean seed extract obtained, stirs evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds 150g apple Extract, 60g pepper seed extract and 5g rhEGF, each component discharge after mixing evenly can be prepared by it is described have beauty and change The creme of kind subhealth symptom.
Embodiment 3:
(1) 350g brown alga extract is dissolved in 2.7L dehydrated alcohol, it is 50-90 nanometers that 450g average grain diameter, which is then added, Porous nano titanium dioxide microballoon sphere, gained mixture is in 45 DEG C of heating stirring 2h, then 50 DEG C of dryings in a vacuum drying oven 36h removes solvent and the coated porous nanometer titanium dioxide micro-sphere of brown alga extract is made, spare;
(2) 500g ash green soy bean seed extract is dissolved in 5L dehydrated alcohol, 550g average grain diameter is then added and is received for 50-90 The porous nano titanium dioxide microballoon sphere of rice, gained mixture in 45 DEG C of heating stirring 3h, then in a vacuum drying oven 50 DEG C it is dry Dry 36h removes solvent and the coated porous nanometer titanium dioxide micro-sphere of grey green soy bean seed extract is made;
(3) 100g moutan root bark, 100g borneol, 100g motherwort, 150g Asian puccoon, 100g oat, 350g bark of ash first are weighed Element and 100g aurantiamarin mix after crushing respectively, and 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, are made mixed Close powder;
(4) by 150g serine, 200g resveratrol, 100g Sodium Hyaluronate, 30g atriphos, 100g gluathione Peptide and 30g creatine, which are added in 5L water to stir evenly, is heated to 75 DEG C and 60 minutes obtained aqueous mixtures of constant temperature;
(5) by 150g lactoprotein, 350g walnut oil, 200g Purple Perilla Seed Oil, 150g lavender oil, 140g ginger oil, 750g Olive oil PEG-6 esters, 25g ginsenoside, 100g astaxanthin and 3.5g India poponax resin extract are heated to 80 DEG C and perseverance Warm 60 minutes obtained oil mixtures;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 2 hours, and emulsification pot temperature is down to 45 after emulsification DEG C, then sequentially add system in the coated porous nanometer titanium dioxide micro-sphere of brown alga extract obtained in step (1) and step (2) The grey coated porous nanometer titanium dioxide micro-sphere of green soy bean seed extract obtained, stirs evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds 100g apple Extract, 35g pepper seed extract and 3g rhEGF, each component discharge after mixing evenly can be prepared by it is described have beauty and change The creme of kind subhealth symptom.
The prepared measure of merit with beauty and the creme for improving subhealth symptom of the invention is as follows:
The test of 1 beautifying face of case:
Cooperate with Shanghai and beauty parlor, 100, Jiangsu Province, chooses 1000 40~60 years old age level women and try out, it will The creme with beauty and improvement subhealth symptom that the present invention tries out uniformly is applied to face, and suitably massage promotes to inhale It receives, once in the morning and once at night, 5 as a treatment course, collects trial effect application form every other day, and collected application form data are whole Reason obtains using effect statistical data and is shown in Table 1.
Table 1 has beauty and improves the creme of subhealth symptom to facial improvement statistical data
It has clear improvement It is not improved It is uncertain
After 1 day 687 people 185 people 128 people
After 5 days 812 people 100 people 88 people
After 10 days 897 65 38
After January 975 10 15
As can be seen from Table 1 using the creme provided by the present invention with beauty and improvement subhealth symptom to facial skin The improvement of skin is not only quick, efficient to be also up to 97.5%.
Test is alleviated in 2 inferior health of case:
Cooperate with Shanghai and massage parlour, 50, Jiangsu Province, chooses 500 25~45 years old age levels and asked in the presence of insomnia inferior health The personage (each 250 of men and women) of topic tries out, the creme with beauty and improvement subhealth symptom that the present invention is tried out It is uniformly applied on Dazhui acupoint, tripe flesh and low back, and suitably massage promotes to absorb, once a day, 5 as a treatment course, daily The Intelligent bracelet dormant data for being distributed to user is collected, collected application form data preparation is obtained into using effect statistical number According to being shown in Table 2, wherein sleeping time is more than 40% positive effect that has been denoted as compared to extension before use, and the sleep extension time is more than Effect is general for 10% being denoted as lower than 40%, sleep extension time being denoted as in vain lower than 10%.By collected application form number 2 are shown in Table according to acquisition using effect statistical data is arranged.
Table 2 has beauty and improves the creme of subhealth symptom to inferior health remission effect statistical data
There is positive effect Effect is general In vain
After 1 day 355 people 68 people 77 people
After 5 days 410 people 46 people 44 people
After 10 days 455 21 24
After January 495 2 3
As can be seen from Table 2 using the creme provided by the present invention with beauty and improvement subhealth symptom to inferior health Remission effect it is not only quick, effective percentage also above 98%.

Claims (4)

1. a kind of creme with beauty and improvement subhealth symptom, which is characterized in that described that there is beauty and improve inferior health The material content of the creme of symptom is as follows in parts by weight: 1-2 parts of lactoprotein, 1-2 parts of serine, and apple extract 0.5- 1.5 parts, 1-2.5 parts of resveratrol, 0.5-1.5 parts of moutan root bark, 0.5-1.5 parts of borneol, 0.5-1.5 parts of Sodium Hyaluronate, benefit 0.5-1.5 parts of Brittle Falsepimpernel Herb, 0.1-0.6 parts of pepper seed extract, 2-5 parts of walnut oil, 1-3 parts of Purple Perilla Seed Oil, 1-2 parts of Asian puccoon, smoke clothing Careless 1-2 parts of oil, 0.5-1.5 parts of oat, 0.5-1.5 parts of aurantiamarin .1-0.5 parts of ginsengenin 20, olive oil PEG-6 esters 5-10 Part, 0.5-1.5 parts of glutathione, 1.2-1.6 parts of ginger oil, 0.5-1.5 parts of astaxanthin, 0.1-0.5 parts of atriphos, brown alga 2-5 parts of extract, 2-5 parts of aesculin, 3-7 parts of grey green soy bean seed extract, 0.5-1 parts of creatine, India's poponax resin extract 0.02-0.05 parts, 0.02-0.05 parts of rhEGF, 7-12 parts of porous nano titanium dioxide microballoon sphere, 30-65 parts of water.
2. a kind of preparation method with beauty and the creme for improving subhealth symptom, feature as described in claim 1 exist In specifically comprising the following steps:
(1) brown alga extract is dissolved in dehydrated alcohol, porous nano titanium dioxide microballoon sphere is then added, gained mixture is at 45 DEG C Heating stirring 1h, then 50 DEG C of dryings remove the porous nano that brown alga extract cladding is made in solvent for 24 hours in a vacuum drying oven Titanium dioxide microballoon sphere;
(2) grey green soy bean seed extract is dissolved in dehydrated alcohol, porous nano titanium dioxide microballoon sphere is then added, gained mixture exists 45 DEG C of heating stirring 2h, then 50 DEG C of dryings remove solvent for 24 hours and grey green soy bean seed extract cladding are made in a vacuum drying oven Porous nano titanium dioxide microballoon sphere;
(3) it mixes, is sieved after crushing moutan root bark, borneol, motherwort, Asian puccoon, oat, aesculin and aurantiamarin respectively, Mixed-powder is made;
(4) serine, resveratrol, Sodium Hyaluronate, atriphos, glutathione and creatine are added to the water and are stirred It is even to be heated to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) lactoprotein, walnut oil, Purple Perilla Seed Oil, ginger oil, lavender oil, olive oil PEG-6 esters, ginsenoside, shrimp is green Element and India's poponax resin extract are heated to 80 DEG C and 30 minutes obtained oil mixtures of constant temperature;
(6) in emulsion pot 80 DEG C be vigorously stirred the lower aqueous mixture that will be made in step (4) and be slowly added into system in step (5) The oil mixture obtained is emulsified;Emulsification pot temperature is down to 45 DEG C after emulsification, then sequentially adds system in step (1) Grey green soy bean seed extract obtained is coated porous in the coated porous nanometer titanium dioxide micro-sphere of brown alga extract and step (2) obtained Nanometer titanium dioxide micro-sphere stirs evenly;Then emulsification pot temperature is down to 35 DEG C, mixed-powder obtained in rapid (3) is added, It stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds apple extract, pepper seed extract and rhEGF, each group Discharging after mixing evenly is divided to can be prepared by the creme with beauty and improvement subhealth symptom.
3. the preparation method according to claim 2 with beauty and the creme for improving subhealth symptom, which is characterized in that The average grain diameter of the porous nano titanium dioxide microballoon sphere is 50-90 nanometers.
4. the preparation method according to claim 2 with beauty and the creme for improving subhealth symptom, which is characterized in that The partial size of step (3) described mixed-powder is 70-100 microns.
CN201811401251.5A 2018-11-22 2018-11-22 A kind of creme and preparation method thereof with beauty and improvement subhealth symptom Pending CN109464348A (en)

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CN116712342B (en) * 2023-06-09 2024-03-08 诺德溯源(广州)生物科技有限公司 High-permeability inclusion for relieving skin redness, heat and pain, and preparation method and application thereof

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Application publication date: 20190315