CN109172492A - A kind of fast more frost and preparation method thereof - Google Patents

A kind of fast more frost and preparation method thereof Download PDF

Info

Publication number
CN109172492A
CN109172492A CN201811402031.4A CN201811402031A CN109172492A CN 109172492 A CN109172492 A CN 109172492A CN 201811402031 A CN201811402031 A CN 201811402031A CN 109172492 A CN109172492 A CN 109172492A
Authority
CN
China
Prior art keywords
parts
extract
oil
speed
porous nano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811402031.4A
Other languages
Chinese (zh)
Inventor
叶文远
邹方
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd
Original Assignee
Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd filed Critical Saiduchen Pharmaceutical Biotechnology (shanghai) Co Ltd
Priority to CN201811402031.4A priority Critical patent/CN109172492A/en
Publication of CN109172492A publication Critical patent/CN109172492A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/606Nucleosides; Nucleotides; Nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of speed more frost and preparation method thereof, porous nano silica microballoon, India's poponax resin extract, creatine and the atriphos that the speed more frost is coated with aesculin and America reed tail grass extract is main activated feedstocks, the nutriments such as lactoprotein and serine are added, there is clearing and activating the channels and collaterals substance in conjunction with various naturals and motherwort, borneol, pepper seed extract and angelica extract etc., being organically combined together various natural nutrient substances by the selection and reasonable collocation of science makes it play more preferable effect.Speed provided by the present invention more frost can be absorbed by skin, it can be anti-oxidant, boost metabolism and cell repair, the raising smooth exquisiteness of human skin reach anti-aging effects.In addition, speed more frost provided by the present invention can also dredge the channels, activating microcirculation and removing stasis medicinal, swelling and pain relieving is effective in cure to subhealth symptoms such as cervical spondylosis and scapulohumeral periarthritis.

Description

A kind of fast more frost and preparation method thereof
Technical field
The present invention relates to beauty skin care products, and in particular to a kind of fast more frost and preparation method thereof.
Background technique
As being constantly progressive for society is made with economic sustainable development, the variation of weather and environment to the living environment of the mankind At in increasingly severe pollution, especially air various pollutants matter and various harmful emitting electromagnetic radiations can induce Human body generates free radicals and other harmful organism active materials so as to cause human senility or even cause various diseases.This is because Biological damage can be caused to human body during generating free radicals, is exactly intuitively most that human skin can generate various forms Change and condition, such as dry, nigrescence, coarse and relaxation etc..In addition, plus the study of modern, work and life work It is excessive be easy to cause body endocrine disorder and metabolic disorder so that cause skin wrinkle, the colour of skin it is uneven, it is coarse, lack Elasticity, the gloomy jaundice of the colour of skin, color spot freckle, drying and coarse etc. the inferior health problem of pore.
Common people can select cosmetics or Orally taken health article etc. to reduce or postpone the generation of the above symptom, but external application only Health care product is fewer and fewer.For common skin care item based on moisturizing moisturizing, primary raw material is with moisture-keeping functions currently on the market Various oil compounds, its moisture-keeping functions compare shallow-layer to brought by skin change be also it is of short duration, do not have skin Skin cures the problem of function can not fundamentally improve skin aging, and with less dredging the channels, activating microcirculation and removing stasis medicinal, detumescence stops Bitterly, alleviate the healthcare function of the subhealth symptoms such as cervical spondylosis and scapulohumeral periarthritis.Although Orally taken health article has healthcare function, work The slow and improvement to skin aging and the effect for alleviating inferior health are not too ideal.
With the continuous improvement of people's living standards, requirement of the people to beauty and skin care cosmetics is also higher and higher, in day So, nutrition, in the upsurge to go back to nature, people increasingly tend to use natural health-care products.Therefore, various natural materials are utilized Radiation-resisting functional, anti-oxidizing activities and cell repair function come develop with antioxygen chemoprevention skin aging and promote cell generation The fast more frost for thanking, quickly repairing and alleviating inferior health is significantly.
Summary of the invention
It is an object of the invention to solve the disadvantage that existing external application moisturizing product, provide it is a kind of have it is anti-oxidant, anti-aging and Speed more frost and preparation method thereof of Skin Cell reparation can be rapidly promoted.
In order to achieve the above objectives, solution of the invention is:
A kind of speed is more white, which is characterized in that the more white material content of the speed is as follows in parts by weight: lactoprotein 1- 2 parts, 1-2 parts of serine, 0.5-1.5 parts of apple extract, 1-2.5 parts of resveratrol, 0.5-1.5 parts of moutan root bark, borneol 0.5-1.5 parts, 0.5-1.5 parts of Sodium Hyaluronate, 0.5-1.5 parts of motherwort, 0.1-0.6 parts of pepper seed extract, walnut oil 2-5 Part, 1-3 parts of Purple Perilla Seed Oil, 1-2 parts of Asian puccoon, 1-2 parts of lavender oil, 0.5-1.5 parts of oat, 0.5-1.5 parts of aurantiamarin, ginseng soap 0.1-0.5 parts of glycosides, 5-10 parts of olive oil PEG-6 esters, 0.5-1.5 parts of glutathione, 1.2-1.6 parts of ginger oil, astaxanthin 0.5-1.5 parts, 0.1-0.5 parts of atriphos, 2-5 parts of aesculin, 1-2 parts of angelica extract, America reed tail grass extract 3-7 parts, 0.5-1 parts of creatine, 0.02-0.05 parts of India's poponax resin extract, 0.02-0.05 parts of rhEGF, porous nano two 7-12 parts of silicon oxide microsphere, 30-65 parts of water.
A kind of preparation method that speed is more white, which is characterized in that specifically comprise the following steps:
(1) aesculin is dissolved in dehydrated alcohol, porous nano silica microballoon is then added, gained mixture is 45 DEG C heating stirring 1h, then 50 DEG C of dryings remove solvent for 24 hours and the coated porous nanometer two of aesculin are made in a vacuum drying oven Silicon oxide microsphere;
(2) America reed tail grass extract is dissolved in dehydrated alcohol, porous nano silica microballoon is then added, gained is mixed Object is closed in 45 DEG C of heating stirring 2h, then 50 DEG C of dryings remove solvent for 24 hours and the extraction of America reed tail grass is made in a vacuum drying oven The coated porous nano silica microsphere of object;
(3) it mixes, is sieved after crushing moutan root bark, borneol, motherwort, Asian puccoon, oat and aurantiamarin respectively, be made mixed Close powder;
(4) serine, resveratrol, Sodium Hyaluronate, atriphos, glutathione and creatine are added to the water and are stirred It mixes and is heated uniformly to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) by lactoprotein, walnut oil, Purple Perilla Seed Oil, ginger oil, lavender oil, olive oil PEG-6 esters, ginsenoside, Astaxanthin and India's poponax resin extract are heated to 80 DEG C and 30 minutes obtained oil mixtures of constant temperature;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified;Emulsification pot temperature is down to 45 DEG C after emulsification, then sequentially adds step (1) In America reed tail grass extract cladding obtained in the coated porous nano silica microsphere of aesculin obtained and step (2) Porous nano silica microballoon, stirs evenly;Then emulsification pot temperature is down to 35 DEG C, mixing obtained in rapid (3) is added Powder stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, apple extract, angelica extract, pepper seed is sequentially added and mentions Object and rhEGF are taken, each component discharges after mixing evenly can be prepared by the speed more frost.
Preferably, the average grain diameter of the porous nano silica microballoon is 30-50 nanometers.
Preferably, the partial size of step (3) described mixed-powder is 70-100 microns.
Chief active raw material used in the present invention is described in detail below:
Aesculin has anti-inflammatory, antibacterial, anticoagulant, analgesia isoreactivity, has significant diuresis to mouse.It can inhibit The aldose reductase of rat crystalline lens is the growth inhibitor of hay bacillus, while to chemically also having inhibiting effect to cancer.
It is old that America reed tail grass extract can resist tissue sorrow, can remove free radical, prevent cell membrane by free radical and Aging Damage is resisted in air pollution, can be played blood circulation of releiving, be eliminated what climacteric obstacle delayed senescence with conditioning skin and losing Effect, for tumour, chemicotherapy repairing effect is can be improved in disease patient, is had for endocrine disorder and is restored cell activity oxygen content, Improve bone density, prevent mammary gland tumour, maintains endometrium function and other effects.
Containing substances such as Ligustilide, n-butene acyl lactone and ferulic acids in angelica extract, there is blood-nourishing and blood, tune of enriching blood Through with promoting blood circulation and stopping pain and other effects.
Resveratrol is a kind of natural antioxidant, inhibits coagulating platelets and vasodilation, keeps unobstructed blood, tool There are antiatherosclerosis and coronary heart disease, ischemic heart disease, the preventive and therapeutic effect of blood lipid.Have and brings down a fever and analgesic effect, angiocarpy Protective effect promotes immune system activity, free radical resisting, anti-inflammatory, antibacterial, promotes longevity.
Lactoprotein can be such that pore expands, and promote blood circulation, and enhance suction of the skin to nutriment and bioactie agent It receives.
Serine facilitates the generation of immunoglobulin and antibody, in manufacture processing, musculature and the encirclement of cell membrane Effect is all played in the synthesis of the sheath of nerve cell, silk ammonia serine can promote the metabolism of fat and fatty acid, help In maintenance immune system.
The warm-natured heat of pepper seed has good relaxation effect, and treats chill to stomach abdomen crymodynia, borborygmus diarrhea caused by stomach cold Flu, can cold dispelling, stomach invigorating etc., can improve a poor appetite, is aid digestion, inspiring sweat;Women abnormal leucorrhea and epilepsy can also be improved.
Purple perilla has relieving exterior syndrome and dispelling cold, and relieving QI stagnancy in the stomach is usually used in treating anemofrigid cold, cough evil of vomitting and fish and crab poisoning etc..
Aurantiamarin is the drug for treating hypertension and myocardial infarction, one of main composition of Chinese patent drug Maitong.Aurantiamarin tool There are lipid peroxidation inhibition, scavenging activated oxygen, anti-inflammatory, antiviral, antibacterial action, long-time service can delay senescence and anticancer.
Borneol has the function of inducing resuscitation of having one's ideas straightened out, clearing heat for detumescence, analgesic etc., can be used for treating divine coma, apoplexy coma due to blocking of the respiratory system, gas It faints, the diseases such as middle evil, sore swell and ache curative, aphtha, abscess of throat, eye illness, swelling and aching of gum.For the treatment of coronary heart diseases and angina pectoris, control It is scorching to treat chronic nasal cavity, can be used for neuralgia and anti-inflammatory.Borneol mucous membrane, subcutaneous tissue bacterium be easy absorb, and in vivo with grape Uronic acid excretes after combining.
Astaxanthin has a variety of physiological functions, such as in inoxidizability, antitumor, pre- anti-cancer, strengthen immunity and improvement Eyesight etc. has certain effect.
Motherwort has treatment menoxenia, vaginal bleeding during pregnancy difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia leakage Under, hematuria, rush down blood, carbuncle swells sore and platelet aggregation, there are also enhance body cellular immunity the effects of, increase coronary artery stream Amount reduces coronary resistance, reducing heart rate and the effect for reducing output quantity and left ventricular work, there is direct excitation.
Ginsenoside has rapid recovery fatigue, delays senescence, is anti-oxidant, accelerating cell repair and skin injury is promoted to be cured The effects of conjunction.
Apple extract vitamin C rich in has effects that toxin-expulsion oxidation-resistance, delaying skin aging, moisturizing and resists Wrinkle effect.
Moutan root bark can inhibit skin free radical to generate, and promote blood circulation, and improve the colour of skin and pore refining and other effects.
Glutathione oxidation resistance with super strength can quickly remove interior free yl, protective inner cell not by oxygen Change damage, anti-aging and antifatigue and anticancer function.
The beta glucan molecule that oat contains has the function of that enhancing immunocompetence improves blood lipid and anti-radiation.
Atriphos and creatine can store and transmit energy for Skin Cell, be the important sources of skin energy, can be with Skin Cell biologos is stimulated, skin ageing is continued, hence it is evident that improves skin quality and the colour of skin.
Sodium Hyaluronate can play unique protective effect to skin, and skin moisturizing can be kept smooth, fine and smooth tender, rich Elasticity has the function of wrinkle resistant, crease-resistant, beauty and health care and restores skin physiology function.
Lavender can be clearing heat and detoxicating, cleaning skin, controls oil, freckle removing and whitening, the tender skin of anti-wrinkle, eye haustra -dsipelling are black Eyelet may additionally facilitate the skin-protecting functions such as regeneration of damaged tissue recovery.
The gingerol and its derivative contained in ginger oil has very strong oxidation resistance, especially very strong to anti-grease The effect of brown element, can substantially reduced senile plaque.
India's poponax resin extract has activating microcirculation and removing stasis medicinal, swelling and pain relieving and inhibition scytitis and other effects.
RhEGF recombinant human epidermal growth factor have with natural hEGF's said function, cell can be promoted Reparation and regeneration, have for the wound repair of the wound repair of skin, cornea tissue, ontogeny and internal organs very heavy The effect wanted.
The principle of the present invention and gain effect are as follows:
(1) the present invention provides a kind of, and the speed with multi-functional and effect is more white, by the selection of science and reasonably takes It is set to play more preferable effect with above-mentioned natural nutrient substance to be organically combined together.Speed provided by the present invention is cured White to be uniformly applied to skin surface and carry out Transdermal absorption by massage, it can be anti-oxidant, boosts metabolism and cell repair, mentions The high smooth exquisiteness of human skin, and then reach anti-aging effects, fundamentally improve human skin aging problem.
(2) by speed provided by the present invention more frost be applied to positions such as Dazhui acupoint, tripe flesh and low back and then pass through massage into Row Transdermal absorption, it can dredge the channels, activating microcirculation and removing stasis medicinal, and swelling and pain relieving is effective in cure to cervical spondylosis scapulohumeral periarthritis etc..
(3) it is micro- creatively to be loaded to porous nano silica by the present invention for aesculin and America reed tail grass extract In ball, the aesculin and America reed tail grass extract being supported on porous nano silica microballoon in this way can be more white in speed In constantly persistently play effect, play the role of sustained release, this is more advantageous to skin to aesculin and America reed tail grass extract Absorption, effectively improve the utilization efficiency and curative effect of both nutriments.In addition, nano silica itself also has To anti-ultraviolet optical property, and nontoxic, tasteless, pollution-free it is widely used in cosmetics.
(4) primary raw material selected by the present invention is natural products, environmentally protective, simple and easy to get.The present invention prepares speed More white method also has many advantages, such as simple and easy, mild condition and easily controllable.
Specific embodiment
Further below in conjunction with the embodiments with the present invention will be described in detail.It will similarly be understood that following embodiment is served only for this Invention is further described, and should not be understood as limiting the scope of the invention, specific quality, reaction time in example With the example that temperature, technological parameter etc. are also only in OK range, those skilled in the art is according to the present invention above-mentioned Some nonessential modifications and adaptations that content is made all belong to the scope of protection of the present invention.
Agents useful for same is not further purified as being commercial reagents without particularly pointing out using preceding.
Embodiment 1:
The more white preparation step of speed is as follows:
(1) 200g aesculin is dissolved in 1.5L dehydrated alcohol, it is 30-50 nanometers that 250g average grain diameter, which is then added, Porous nano silica microballoon, gained mixture is in 45 DEG C of heating stirring 1h, and then 50 DEG C of dryings are for 24 hours in a vacuum drying oven It removes solvent and the coated porous nano silica microsphere of aesculin is made, it is spare;
(2) America 300g reed tail grass extract is dissolved in 2L dehydrated alcohol, it is 30-50 that 450g average grain diameter, which is then added, The porous nano silica microballoon of nanometer, gained mixture is in 45 DEG C of heating stirring 2h, and then in a vacuum drying oven 50 DEG C The coated porous nano silica microsphere of America reed tail grass extract is made in the dry solvent that removes for 24 hours;
(3) 50g moutan root bark, 50g borneol, 50g motherwort, 100g Asian puccoon, 50g oat and 50g aurantiamarin difference are weighed It is mixed after crushing, 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, and mixed-powder is made;
(4) by 100g serine, 100g resveratrol, 50g Sodium Hyaluronate, 10g atriphos, 50g glutathione It is added in 3L water to stir evenly with 50g creatine and is heated to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) by 100g lactoprotein, 200g walnut oil, 100g Purple Perilla Seed Oil, 100g lavender oil, 120g ginger oil, 500g Olive oil PEG-6 esters, 10g ginsenoside, 50g astaxanthin and 2g India poponax resin extract are heated to 80 DEG C and constant temperature 30 Minute obtained oil mixture;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 1 hour, and emulsification pot temperature is down to 45 after emulsification DEG C, it then sequentially adds and is made in the coated porous nano silica microsphere of aesculin obtained in step (1) and step (2) The coated porous nano silica microsphere of America reed tail grass extract, stir evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, 50g apple is sequentially added and mentions Object, 100g angelica extract, 10g pepper seed extract and 2g rhEGF are taken, each component discharges after mixing evenly can be prepared by institute It is more white to state speed.
Embodiment 2
(1) 500g aesculin is dissolved in 4L dehydrated alcohol, it is 30-50 nanometers more that 500g average grain diameter, which is then added, Hole nano silica microsphere, gained mixture is in 45 DEG C of heating stirring 3h, and then 50 DEG C of dry 48h are removed in a vacuum drying oven Go solvent that the coated porous nano silica microsphere of aesculin is made, it is spare;
(2) America 700g reed tail grass extract is dissolved in 7L dehydrated alcohol, it is 30-50 that 700g average grain diameter, which is then added, The porous nano silica microballoon of nanometer, gained mixture is in 45 DEG C of heating stirring 5h, and then in a vacuum drying oven 50 DEG C Dry 48h removes solvent and the coated porous nano silica microsphere of America reed tail grass extract is made;
(3) 150g moutan root bark, 150g borneol, 150g motherwort, 200g Asian puccoon, 150g oat and 150g aurantiamarin are weighed It is mixed after crushing respectively, 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, and mixed-powder is made;
(4) by 200g serine, 250g resveratrol, 150g Sodium Hyaluronate, 50g atriphos, 150g gluathione Peptide and 100g creatine, which are added in 6.5L water to stir evenly, is heated to 75 DEG C and 90 minutes obtained aqueous mixtures of constant temperature;
(5) by 200g lactoprotein, 500g walnut oil, 300g Purple Perilla Seed Oil, 200g lavender oil, 160g ginger oil, 1000g Olive oil PEG-6 esters, 50g ginsenoside, 150g astaxanthin and 5g India poponax resin extract are heated to 80 DEG C and constant temperature 90 minutes obtained oil mixtures;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 3 hours, and emulsification pot temperature is down to 45 after emulsification DEG C, it then sequentially adds and is made in the coated porous nano silica microsphere of aesculin obtained in step (1) and step (2) The coated porous nano silica microsphere of America reed tail grass extract, stir evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds 150g apple Extract, 200g angelica extract, 60g pepper seed extract and 5g rhEGF, each component discharge can be prepared by after mixing evenly The speed is more white.
Embodiment 3:
(1) 350g aesculin is dissolved in 2.7L dehydrated alcohol, it is 30-50 nanometers that 450g average grain diameter, which is then added, Porous nano silica microballoon, gained mixture is in 45 DEG C of heating stirring 2h, then 50 DEG C of dry 36h in a vacuum drying oven It removes solvent and the coated porous nano silica microsphere of aesculin is made, it is spare;
(2) America 500g reed tail grass extract is dissolved in 5L dehydrated alcohol, it is 30-50 that 550g average grain diameter, which is then added, The porous nano silica microballoon of nanometer, gained mixture in 45 DEG C of heating stirring 3h,
Then 50 DEG C of dry 36h remove solvent and the coated porous nanometer of America reed tail grass extract are made in a vacuum drying oven Silicon dioxide microsphere;
(3) 100g moutan root bark, 100g borneol, 100g motherwort, 150g Asian puccoon, 100g oat and 100g aurantiamarin are weighed It is mixed after crushing respectively, 130 mesh of sieving are mixed to the partial size of powder between 70-100 microns, and mixed-powder is made;
(4) by 150g serine, 200g resveratrol, 100g Sodium Hyaluronate, 30g atriphos, 100g gluathione Peptide and 30g creatine, which are added in 5L water to stir evenly, is heated to 75 DEG C and 60 minutes obtained aqueous mixtures of constant temperature;
(5) by 150g lactoprotein, 350g walnut oil, 200g Purple Perilla Seed Oil, 150g lavender oil, 140g ginger oil, 750g Olive oil PEG-6 esters, 25g ginsenoside, 100g astaxanthin and 3.5g India poponax resin extract are heated to 80 DEG C and perseverance Warm 60 minutes obtained oil mixtures;
(6) in emulsion pot 80 DEG C be vigorously stirred it is lower will in step (4) be made aqueous mixture be slowly added into step (5) In oil mixture obtained emulsified, which takes around 2 hours, and emulsification pot temperature is down to 45 after emulsification DEG C, it then sequentially adds and is made in the coated porous nano silica microsphere of aesculin obtained in step (1) and step (2) The coated porous nano silica microsphere of America reed tail grass extract, stir evenly;Then emulsification pot temperature is down to 35 DEG C, Mixed-powder obtained in rapid (3) is added, stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds 100g apple Extract, 150g angelica extract, 35g pepper seed extract and 3g rhEGF, each component discharge can be prepared by after mixing evenly The speed is more white.
The more white measure of merit of speed prepared by the present invention is as follows:
The test of 1 beautifying face of case:
Cooperate with Shanghai and beauty parlor of 100, Jiangsu Province, chooses 1000 40~60 years old age level women and try out, it will The speed that the present invention tries out more frost is uniformly applied to face, and suitably massage promotes to absorb, and once in the morning and once at night, 5 are one A course for the treatment of collects trial effect application form every other day, and collected application form data preparation acquisition using effect statistical data is shown in Table 1.
1 speed of table more frost is to facial improvement statistical data
It is not only quick to the improvement of skin of face using speed provided by the present invention more frost as can be seen from Table 1, It is efficient to be also up to 97.2%.
Case 2 alleviates cervical spondylosis test:
Massaging and physiotherapeutical institute cooperates with 10, Shanghai City, choose 100 35~55 years old age levels there are the personage of cervical spondylosis into Row is on probation, and speed provided by the present invention more frost is uniformly applied on cervical vertebra, and suitably massage promotes to absorb, once a day, 5 days It is as a treatment course, trial effect application form is collected every other day, and collected application form data preparation is obtained into using effect statistical number According to being shown in Table 2.
2 speed of table more frost is to cervical spondylosis remission effect statistical data
It is relieved It is not relieved It is uncertain
After 1 day 85 people 9 people 6 people
After 5 days 94 people 3 people 3 people
After 10 days 97 1 2
After January 99 0 1
It is not only quick to the remission effect of cervical spondylosis using speed provided by the present invention more frost as can be seen from Table 2, have Efficiency is up to 99%.

Claims (4)

1. a kind of speed is more white, which is characterized in that the more white material content of the speed is as follows in parts by weight: lactoprotein 1-2 Part, 1-2 parts of serine, 0.5-1.5 parts of apple extract, 1-2.5 parts of resveratrol, 0.5-1.5 parts of moutan root bark, borneol 0.5- 1.5 parts, 0.5-1.5 parts of Sodium Hyaluronate, 0.5-1.5 parts of motherwort, 0.1-0.6 parts of pepper seed extract, 2-5 parts of walnut oil, 1-3 parts of Purple Perilla Seed Oil, 1-2 parts of Asian puccoon, 1-2 parts of lavender oil, 0.5-1.5 parts of oat, 0.5-1.5 parts of aurantiamarin, ginsenoside 0.1-0.5 parts, 5-10 parts of olive oil PEG-6 esters, 0.5-1.5 parts of glutathione, 1.2-1.6 parts of ginger oil, astaxanthin 0.5- 1.5 parts, 0.1-0.5 parts of atriphos, 2-5 parts of aesculin, 1-2 parts of angelica extract, America reed tail grass extract 3-7 Part, 0.5-1 parts of creatine, 0.02-0.05 parts of India's poponax resin extract, 0.02-0.05 parts of rhEGF, porous nano titanium dioxide 7-12 parts of silicon microballoon, 30-65 parts of water.
2. a kind of preparation method that speed as described in claim 1 is more white, which is characterized in that specifically comprise the following steps:
(1) aesculin is dissolved in dehydrated alcohol, porous nano silica microballoon is then added, gained mixture adds at 45 DEG C Thermal agitation 1h, then 50 DEG C of dryings remove the porous nano dioxy that aesculin cladding is made in solvent for 24 hours in a vacuum drying oven SiClx microballoon;
(2) America reed tail grass extract is dissolved in dehydrated alcohol, porous nano silica microballoon, gained mixture is then added In 45 DEG C of heating stirring 2h, then 50 DEG C of dryings remove solvent for 24 hours and America reed tail grass extract packet are made in a vacuum drying oven The porous nano silica microballoon covered;
(3) it mixes, is sieved after crushing moutan root bark, borneol, motherwort, Asian puccoon, oat and aurantiamarin respectively, mixed powder is made End;
(4) serine, resveratrol, Sodium Hyaluronate, atriphos, glutathione and creatine are added to the water and are stirred It is even to be heated to 75 DEG C and 40 minutes obtained aqueous mixtures of constant temperature;
(5) lactoprotein, walnut oil, Purple Perilla Seed Oil, ginger oil, lavender oil, olive oil PEG-6 esters, ginsenoside, shrimp is green Element and India's poponax resin extract are heated to 80 DEG C and 30 minutes obtained oil mixtures of constant temperature;
(6) in emulsion pot 80 DEG C be vigorously stirred the lower aqueous mixture that will be made in step (4) and be slowly added into system in step (5) The oil mixture obtained is emulsified;Emulsification pot temperature is down to 45 DEG C after emulsification, then sequentially adds system in step (1) America reed tail grass extract obtained is coated porous in the coated porous nano silica microsphere of aesculin and step (2) obtained Nano silica microsphere stirs evenly;Then emulsification pot temperature is down to 35 DEG C, mixed-powder obtained in rapid (3) is added, It stirs evenly;Emulsification pot temperature is finally down to 30 DEG C, sequentially adds apple extract, angelica extract, pepper seed extract And rhEGF, each component discharges after mixing evenly can be prepared by the speed more frost.
3. the more white preparation method of speed according to claim 2, which is characterized in that the porous nano silica microballoon Average grain diameter be 30-50 nanometers.
4. the more white preparation method of speed according to claim 2, which is characterized in that the grain of step (3) described mixed-powder Diameter is 70-100 microns.
CN201811402031.4A 2018-11-22 2018-11-22 A kind of fast more frost and preparation method thereof Pending CN109172492A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811402031.4A CN109172492A (en) 2018-11-22 2018-11-22 A kind of fast more frost and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811402031.4A CN109172492A (en) 2018-11-22 2018-11-22 A kind of fast more frost and preparation method thereof

Publications (1)

Publication Number Publication Date
CN109172492A true CN109172492A (en) 2019-01-11

Family

ID=64938235

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811402031.4A Pending CN109172492A (en) 2018-11-22 2018-11-22 A kind of fast more frost and preparation method thereof

Country Status (1)

Country Link
CN (1) CN109172492A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112022778A (en) * 2019-06-03 2020-12-04 江苏光博士医疗科技有限公司 Composition containing yellow wine extract and application of composition in washing and caring products

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1394593A (en) * 2002-05-15 2003-02-05 孙和平 Equilibrium cream and its preparation method
KR20030018863A (en) * 2001-08-31 2003-03-06 주식회사 알로에마임 A Silica Composition Containing an Aloe and a Cosmetic Composition Containing a Silica Composition and Method of Manufacturing a Cosmetic Composition Utilizing Aloe
CN102085172A (en) * 2011-01-25 2011-06-08 深圳市金因生物技术有限公司 Skin care cosmetic taking American wild yam extract as main component and preparation method thereof
CN105616174A (en) * 2016-01-28 2016-06-01 广州媛点生物科技有限公司 Microsphere wrapped with skin-whitening active ingredient, preparation method of microsphere wrapped with skin-whitening active ingredient and skin-whitening cosmetic
KR20160148450A (en) * 2015-06-16 2016-12-26 (주) 우노코스 Multifunctional cosmetic composition comprising porous silica impregnated with plant complex extract as effective component
CN108309857A (en) * 2018-04-04 2018-07-24 上海易点电子商务股份有限公司 Equilibrium cream and preparation method thereof
CN108553359A (en) * 2018-05-26 2018-09-21 四川宏泰业新科技有限公司 A kind of Shu Huoshuan and preparation method thereof with relaxing tendons and activating collaterals effect
CN108618987A (en) * 2017-09-21 2018-10-09 北京幽美生物科技有限公司 A kind of external preparation of skin nursing and preparation method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030018863A (en) * 2001-08-31 2003-03-06 주식회사 알로에마임 A Silica Composition Containing an Aloe and a Cosmetic Composition Containing a Silica Composition and Method of Manufacturing a Cosmetic Composition Utilizing Aloe
CN1394593A (en) * 2002-05-15 2003-02-05 孙和平 Equilibrium cream and its preparation method
CN102085172A (en) * 2011-01-25 2011-06-08 深圳市金因生物技术有限公司 Skin care cosmetic taking American wild yam extract as main component and preparation method thereof
KR20160148450A (en) * 2015-06-16 2016-12-26 (주) 우노코스 Multifunctional cosmetic composition comprising porous silica impregnated with plant complex extract as effective component
CN105616174A (en) * 2016-01-28 2016-06-01 广州媛点生物科技有限公司 Microsphere wrapped with skin-whitening active ingredient, preparation method of microsphere wrapped with skin-whitening active ingredient and skin-whitening cosmetic
CN108618987A (en) * 2017-09-21 2018-10-09 北京幽美生物科技有限公司 A kind of external preparation of skin nursing and preparation method thereof
CN108309857A (en) * 2018-04-04 2018-07-24 上海易点电子商务股份有限公司 Equilibrium cream and preparation method thereof
CN108553359A (en) * 2018-05-26 2018-09-21 四川宏泰业新科技有限公司 A kind of Shu Huoshuan and preparation method thereof with relaxing tendons and activating collaterals effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
柳红芳: "《常用中草药彩色图谱》", 31 January 2017, 辽宁科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112022778A (en) * 2019-06-03 2020-12-04 江苏光博士医疗科技有限公司 Composition containing yellow wine extract and application of composition in washing and caring products

Similar Documents

Publication Publication Date Title
CN109464348A (en) A kind of creme and preparation method thereof with beauty and improvement subhealth symptom
CN104921983A (en) Medical biological repairing dressing for pregnant woman striae gravidarum and preparation method thereof
CN104041828A (en) Lycium ruthenicum murr tablets with functions of whitening and removing freckles
CN106265137A (en) Pure Chinese medicine whitening and speckle dispelling beautifying facial mask powder and preparation technology thereof
CN109172491A (en) A kind of creme and preparation method thereof with anti-aging and activating microcirculation and removing stasis medicinal function
CN103860449A (en) Skin care product with effect of removing stretch marks and preparation method thereof
CN104116022B (en) For composite heal-care food improving climacteric syndrome and preparation method thereof
CN103877247B (en) Medicine being used for the treatment of decubital ulcer and preparation method thereof
CN104126744A (en) Lycium ruthenicum Murr anti-agingbeauty tablet
CN101028027A (en) Chewing gum with breast-enlarging and beautifying functions
CN103892269A (en) Black medlar sun-screening and whitening tablet
CN106362125A (en) Health-care foot patch and application method thereof
CN109172492A (en) A kind of fast more frost and preparation method thereof
CN102008083B (en) Health food for alleviating physical fatigue and removing chloasma
CN101953971A (en) Nourishing wine
CN110179708A (en) A kind of plant assigns essential oil living and preparation method
CN101297705B (en) Compound Tibet sheep placenta capsule for removing wrinkle and resisting aging
CN108030012A (en) A kind of healthy food with body beautification moistening face
CN111011855B (en) Composition for improving skin complexion and promoting hair growth
CN1238032C (en) Tincture for curing acne and preparation method
CN107156817A (en) Matrimony vine breast augmentation ferment
CN102266427A (en) Cartialgenous and angelica wine for maintaining beauty and keeping young as well as preparation method and application thereof
CN106074732A (en) A kind of antipsoriatics thing and preparation method thereof
CN1358532A (en) Traditional Chinese medicine for treating arthralgia-syndrome
CN109646359A (en) Rose-agaric mud membrane paste with effects of cleaning, purifying, maintaining beauty and keeping young and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20190111

RJ01 Rejection of invention patent application after publication