CN105287340A - Whitening moisture-retention eye cream and preparation method thereof - Google Patents
Whitening moisture-retention eye cream and preparation method thereof Download PDFInfo
- Publication number
- CN105287340A CN105287340A CN201510799232.2A CN201510799232A CN105287340A CN 105287340 A CN105287340 A CN 105287340A CN 201510799232 A CN201510799232 A CN 201510799232A CN 105287340 A CN105287340 A CN 105287340A
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- parts
- extract
- eye cream
- skin
- aloe
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- A—HUMAN NECESSITIES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of cosmetics, and concretely relates to a whitening moisture-retention eye cream and a preparation method thereof. The whitening moisture-retention eye cream comprises Vaseline, hydroxyethyl cellulose, glycerin, butylene glycol, polydimethylsiloxane, coconut oil, cetostearyl alcohol, sorbitol, vitamin E, methyl glucose sesquistearate, an eucommia extract product, a seed of Job's tears extract product, an aloe extract product, pearl powder, roe essence, milk protein, carbomer, diethanolamine, tranexamic acid, polyethylene glycol fatty acid ester, essence, an antiseptic and water. The whitening moisture-retention eye cream has advantages of good permeability and easy absorption, has efficacy for enhancing skin elastic force around the eyes, improving drying and relax phenomena, restoring damaged or nutrition-lacked cells, and obviously delaying skin aging, full and round skin around the eyes can be recovered, and beautiful and bright eyes can be presented.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of whitening skin and preserving moisture eye cream and preparation method thereof.
Background technology
Eye cream, one of skin type cosmetic product, be used to the skin protecting around eyes thinner, it has moist effect, has certain effect to eye pouch, black eye, crows-feet, dry stricture of vagina, microgroove etc.Eye cream product has much in the market, but ubiquity poor permeability, not easily absorbs, the problems such as result of use is not obvious, and meanwhile, the skin of eye is very careful and fragile, easily comes to harm, and therefore, eye cream needs gentleness, do not stimulate, hypoallergenic.
Chinese patent 201310497741.0 discloses a kind of moisturizing whitening eye cream, and it comprises Margarita, Borax, muscone, oil phase, zinc carbonate hydroxide, alcohol-based mixtures, glycerol monostearate, nipasol, glycerol, polyacrylamide, EDETATE SODIUM, methyl hydroxybenzoate, soybean peptide, oxidoreductase, hydrolysis rice bran protein, polydimethylsiloxane, propyl hydroxybenzoate, citric acid, antiseptic imidazolidinyl urea, essence, deionized water.This eye cream has without greasy, easy painting exhibition, uses comfortable, strengthens eye cell viability performance, have consumption few, the advantage of instant effect, but this eye cream permeability is poor, not easily absorbs, and whitening skin and preserving moisture effect is not remarkable.
Therefore, be necessary to provide a kind of Thief zone, be easy to absorb, whitening skin and preserving moisture eye cream.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of whitening skin and preserving moisture eye cream, it is containing multiple natural nourishing composition, effectively can be gone directly dermal tissue, improves the collagen structure of skin corium more fast, strengthens skin around the eyes elastic force and improve drying, obscure phenomenon, repair impaired or innutritive cell, obvious continuity skin aging, makes skin around the eyes recover plentiful and mellow and full, regains bright two pupil of beautiful gloss.
To achieve these goals, technical scheme of the present invention is as follows:
A kind of whitening skin and preserving moisture eye cream, be made up of the component of following parts by weight: 2 ~ 6 parts, vaseline, hydroxyethyl-cellulose 0.5 ~ 2 part, glycerol 3 ~ 8 parts, butanediol 2 ~ 5 parts, polydimethylsiloxane 2 ~ 5 parts, Oleum Cocois 1.5 ~ 3 parts, cetearyl alcohol 1 ~ 3 part, sorbitol 0.5 ~ 2 part, vitamin E 0.5 ~ 2 part, Glucate SS 0.3 ~ 1.5 part, Cortex Eucommiae extract 6 ~ 12 parts, Semen Coicis extract 3 ~ 8 parts, Aloe extract 3 ~ 8 parts, Margarita powder 2 ~ 6 parts, roe elite 2 ~ 6 parts, milk protein 1 ~ 3 part, carbomer 0.05 ~ 0.5 part, diethanolamine 0.05 ~ 0.5 part, tranexamic acid 0.1 ~ 0.5 part, cithrol 0.002 ~ 0.1 part, 0.003 ~ 0.03 part, essence, antiseptic 0.01 ~ 0.2 part and 60 ~ 70 parts, water.
Further, described whitening skin and preserving moisture eye cream, be made up of the component of following parts by weight: 2 parts, vaseline, hydroxyethyl-cellulose 0.5 part, glycerol 3 parts, butanediol 2 parts, polydimethylsiloxane 2 parts, Oleum Cocois 1.5 parts, cetearyl alcohol 1 part, sorbitol 0.5 part, vitamin E 0.5 part, Glucate SS 0.3 part, Cortex Eucommiae extract 6 parts, Semen Coicis extract 3 parts, Aloe extract 3 parts, Margarita powder 2 parts, roe elite 2 parts, milk protein 1 part, carbomer 0.05 part, diethanolamine 0.05 part, tranexamic acid 0.1 part, cithrol 0.002 part, 0.003 part, essence, antiseptic 0.01 part and 60 parts, water.
Further, described whitening skin and preserving moisture eye cream, be made up of the component of following parts by weight: 6 parts, vaseline, hydroxyethyl-cellulose 2 parts, glycerol 8 parts, butanediol 5 parts, polydimethylsiloxane 5 parts, Oleum Cocois 3 parts, cetearyl alcohol 3 parts, sorbitol 2 parts, vitamin E2 part, Glucate SS 1.5 parts, Cortex Eucommiae extract 12 parts, Semen Coicis extract 8 parts, Aloe extract 8 parts, Margarita powder 6 parts, roe elite 6 parts, milk protein 3 parts, carbomer 0.5 part, diethanolamine 0.5 part, tranexamic acid 0.5 part, cithrol 0.1 part, 0.03 part, essence, antiseptic 0.2 part and 70 parts, water.
Further, described whitening skin and preserving moisture eye cream, be made up of the component of following parts by weight: 4 parts, vaseline, hydroxyethyl-cellulose 1 part, glycerol 6 parts, butanediol 3 parts, polydimethylsiloxane 3 parts, Oleum Cocois 2 parts, cetearyl alcohol 2 parts, sorbitol 1 part, vitamin e1 part, Glucate SS 1 part, Cortex Eucommiae extract 9 parts, Semen Coicis extract 6 parts, Aloe extract 6 parts, Margarita powder 4 parts, roe elite 4 parts, milk protein 2 parts, carbomer 0.3 part, diethanolamine 0.3 part, tranexamic acid 0.3 part, cithrol 0.05 part, 0.05 part, essence, antiseptic 0.1 part and 65 parts, water.
Further, described antiseptic is made up of according to the weight ratio of 2:1 methyl hydroxybenzoate and propyl hydroxybenzoate.
Further, described Cortex Eucommiae extract is obtained by following steps:
S1: get the Cortex Eucommiae, drying and crushing, add the water soaking 45 ~ 60 minutes of medical material gross weight 5 ~ 12 times amount, reflux, extract, 1 ~ 3 time, each 4 ~ 9 hours, filters and retains filtering residue, merging filtrate, obtaining Aqueous extracts;
S2: adding medical material gross weight 5 ~ 12 times amount volume fraction in the filtering residue in S1 is the ethanol of 75 ~ 85%, reflux, extract, 2 ~ 3 times, each 3 ~ 8 hours, filter, merging filtrate, obtains alcohol extract;
S3: merge Aqueous extracts and alcohol extract, after stirring, leaves standstill 12 ~ 24 hours, centrifugal 10 ~ 15 minutes of 2000g, gets supernatant, carries out hyperfiltration treatment, temperature is 25 ~ 40 DEG C, material liquid pH is 6 ~ 8, and inlet pressure is 0.3MPa, the low 0.35kPa of liquid outlet pressure ratio inlet pressure, the pressure wave moment of periodic pressure fluctuation is 0.15 ~ 0.25MPa, when feed liquid stock solution reduces 1/8 ~ 1/4, then the ultrafiltration 1 ~ 2 time that adds water, merge ultrafiltrate; Obtain described Cortex Eucommiae extract.
Further, described Semen Coicis extract is obtained by following steps: pulverize after getting Semen Coicis cleaning, drying, cross 100 ~ 200 mesh sieves, adding Semen Coicis coarse powder weight 6 ~ 15 times amount volume fraction is the ethanol of 70 ~ 85%, soaks 7 ~ 12 hours, supersound extraction twice at 45 ~ 60 DEG C, each 35 ~ 60 minutes, supersonic frequency is 15 ~ 30kHz, filters, merging filtrate, during filtrate reduced in volume to 55 DEG C, relative density is the clear paste of 1.15 ~ 1.25, obtains Semen Coicis extract.
Further, described Aloe extract is obtained by following steps:
S1: get Aloe, cleans, and after drying, is squeezed obtain Aloe mixing juice with squeezer;
S2: the Aloe obtained mixing juice is put in filtering tank, removes impurity, obtain Aloe original juice;
S3: put in vacuum-concentrcted device by Aloe original juice liquid and concentrate, concentrated 2 ~ 3 times of circulation, obtains Aloe extract.
Present invention also offers the preparation method of above-mentioned whitening skin and preserving moisture eye cream, specifically comprise the following steps:
S1: hydroxyethyl-cellulose, Glucate SS, cetearyl alcohol, vaseline, polydimethylsiloxane, Oleum Cocois and antiseptic are placed in oil phase pot, stirs and is heated to 70 ~ 85 DEG C, being stirred to material and dissolving completely, obtain material A;
S2: put into the water of 1/2 in main cooker, opens homogenizing, is slowly sprinkled into by carbomer, stirring and dissolving evenly after by glycerol, sorbitol, butanediol, vitamin E and 1/2 water add in main cooker, be stirred to evenly, be heated to 70 ~ 85 DEG C, insulation 5 ~ 10min;
S3: by material A suction main cooker, then add diethanolamine, open homogenizing, homogenizing 3 ~ 8min, obtains material B, and material B carries out insulation froth breaking;
S4: be cooled to 35 ~ 45 DEG C after material B bubble-free, add after tranexamic acid is molten in advance, add Cortex Eucommiae extract, Semen Coicis extract, Aloe extract, Margarita powder, roe elite, milk protein and essence again, be stirred to evenly, finally add cithrol solvent in advance, be stirred to evenly, namely discharging obtains whitening skin and preserving moisture eye cream.
Cortex Eucommiae extract of the present invention is rich in the unsaturated fatty acid such as linolenic acid, linoleic acid, can safeguard the nutritive equilibrium of cell membrane, resists the infringement of external environment to skin, makes skin present efficient regeneration, moisturizing, the daily life function such as penetrating; Improve the quality of epidermal area, reduce the deposition of pigment, skin care, improves coarse, the obscure skin without light quality; In addition, eucommia ulmoides seed oil is also containing the functional component such as aucubin, chlorogenic acid, and it has good non-oxidizability and the ability of scavenging activated oxygen.
Described Semen Coicis extract contains rich in protein and vitamin, and skin can be made delicate fine and smooth, eliminating mottle with reducing wrinkle, eliminating pigment, thus improving the texture of skin, color and luster and brightness.Barbaloin energy regulation of skin contained by described Aloe extract, has the effect of obvious skin care and Palmitoleic Acid, can promote skin metabolism, be conducive to living again of outer skin tissue, have Promotive union effect to wound.
Described Margarita powder is the good nutritive effect composition of one of human body skin, effectively can improve the barrier function of skin, skin care, increases the degree of hydration of skin, effective restraint of tyrosinase, suppresses and removes free radical, improving skin obscure, improving skin gloss.
Described milk protein contains hydrophilic moisturizing ingredient can protect skin total moisture to prevent from running off, and several amino acids composition can promote the quick reparation of injured skin, can enrich the content of albumen in skin, prevents and reduces wrinkle, makes eye part skin plentiful and flexible.
The molecular structure of the fatty acid that described roe elite contains is extremely similar to human adipose's acid, highly can nourish, compact skin, and the level and smooth wrinkle of energy, increase elasticity, increase the Nutrient Absorption of sub-cloth skin, promote cell metabolism.
Whitening skin and preserving moisture eye cream of the present invention contains Cortex Eucommiae extract, Semen Coicis extract, Aloe extract, Margarita powder, roe elite, milk protein, again in conjunction with basic materials such as propylene glycol of the present invention, polydimethylsiloxane, cetearyl alcohol, each component is worked in coordination with, make whitening skin and preserving moisture eye cream good penetrability of the present invention, easy absorption, deep layer whitening skin and preserving moisture, nourish maintenance eye skin, strengthen skin around the eyes elastic force and improve drying, obscure phenomenon, repairing impaired or innutritive cell, that skin around the eyes is replied is plentiful and mellow and full, regains bright two pupil of beautiful gloss.
Therefore, compared with prior art, advantage of the present invention is:
(1) whitening skin and preserving moisture eye cream of the present invention contains Cortex Eucommiae extract, Semen Coicis extract, Aloe extract, Margarita powder, roe elite, milk protein nutritional labeling, deep layer whitening skin and preserving moisture, nourish maintenance skin, strengthen skin around the eyes elastic force and improve drying, obscure phenomenon, repair impaired or innutritive cell, skin around the eyes is replied plentiful and mellow and full, regain bright two pupil of beautiful gloss.
(2) whitening skin and preserving moisture eye cream safety and stability of the present invention, good penetrability, easily absorbs, and uses rear skin salubrious not sticky; And the preparation method of whitening skin and preserving moisture eye cream of the present invention is simple, condition is controlled, process stabilizing, can be applicable.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, whitening skin and preserving moisture eye cream of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
The raw material (with weight parts) of the embodiment of the present invention 1 ~ 3 and comparative example one, two whitening skin and preserving moisture eye cream is as follows:
The preparation method of whitening skin and preserving moisture eye cream of the present invention:
S1: get the Cortex Eucommiae, drying and crushing, add the water soaking 50 minutes of medical material gross weight 8 times amount, reflux, extract, 2 times, each 6 hours, filters and retains filtering residue, merging filtrate, obtaining Aqueous extracts; In filtering residue, add medical material gross weight 8 times amount volume fraction is the ethanol of 75%, reflux, extract, 3 times, each 6 hours, and filter, merging filtrate, obtains alcohol extract; Merge Aqueous extracts and alcohol extract, after stirring, leave standstill 12 hours, centrifugal 10 minutes of 2000g, gets supernatant, carries out hyperfiltration treatment, temperature is 36 DEG C, material liquid pH is 7, and inlet pressure is 0.3MPa, the low 0.35kPa of liquid outlet pressure ratio inlet pressure, the pressure wave moment of periodic pressure fluctuation is 0.2MPa, when feed liquid stock solution reduces 1/54, then the ultrafiltration 2 times that adds water, merge ultrafiltrate; Obtain described Cortex Eucommiae extract;
S2: get Semen Coicis and clean, crushed after being dried, cross 200 mesh sieves, adding Semen Coicis coarse powder weight 8 times amount volume fraction is the ethanol of 70 ~ 85%, soak 9 hours, supersound extraction twice at 45 DEG C, each 45 minutes, supersonic frequency was 20kHz, filter, merging filtrate, during filtrate reduced in volume to 55 DEG C, relative density is the clear paste of 1.20, obtains Semen Coicis extract;
S3: get Aloe, cleans, and after drying, is squeezed obtain Aloe mixing juice with squeezer; : the Aloe obtained mixing juice is put in filtering tank, removes impurity, obtain Aloe original juice; Put in vacuum-concentrcted device by Aloe original juice liquid and concentrate, concentrated 2 times of circulation, obtains Aloe extract;
S4: hydroxyethyl-cellulose, Glucate SS, cetearyl alcohol, vaseline, polydimethylsiloxane, Oleum Cocois and antiseptic are placed in oil phase pot, stirs and is heated to 75 DEG C, being stirred to material and dissolving completely, obtain material A;
S5: put into the water of 1/2 in main cooker, opens homogenizing, is slowly sprinkled into by carbomer, stirring and dissolving evenly after by glycerol, sorbitol, butanediol, vitamin E and 1/2 water add in main cooker, be stirred to evenly, be heated to 75 DEG C, insulation 10min;
S6: by material A suction main cooker, then add diethanolamine, open homogenizing, homogenizing 8min, obtains material B, and material B carries out insulation froth breaking;
S7: be cooled to 45 DEG C after material B bubble-free, add after tranexamic acid is molten in advance, add Cortex Eucommiae extract, Semen Coicis extract, Aloe extract, Margarita powder, roe elite, milk protein and essence again, be stirred to evenly, finally add cithrol solvent in advance, be stirred to evenly, namely discharging obtains whitening skin and preserving moisture eye cream.
Wherein, the rotating speed of described homogenizing is 3000rpm, and the mixing speed of described stirring is 50r/min.
The preparation method of the preparation method reference embodiment of the present invention 3 of comparative example one, two.
Meet the pertinent regulations requirement of QB/T1857 ~ 2013 through inspection embodiment 1 ~ 3 product, sense index (color and luster, fragrance, structure) meets industry regulation, and physical and chemical index (PH, heat-resisting, cold-resistant, active matter) meets industry regulation.
test example one, Product Safety evaluation (experiment of human body skin patch)
One, trial target: the eye cream that embodiment 1 ~ 3, comparative example one, two prepare.
Tested crowd's number: 100 people, women.
Age: between 25 ~ 60 years old.
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: 5 groups, often organize 20 people, 28 ± 2 years old mean age.
Two, patch method: select qualified speckle examination device, with closed patch experiment method, tested material being about 0.025g ~ 0.025g drips in speckle examination device, external special adhesive tape is covered on experimenter back, tested material is removed after 24 hours, within after removing respectively 0.5,6,12,24,48 hour, observe dermoreaction, according to its result of dermoreaction grade scale record in " cosmetics health specification ".
Three, experimental result: human skin patch result shows: each group experimenter is by the patch test of the eye cream of embodiment 1 ~ 3, comparative example one, two, dermoreaction is observed at 0.5,6,12,24,48 hour, wherein there is skin adverse reaction in 0 example, the whitening skin and preserving moisture eye cream use safety described in explanation.
test example two, product effect assessment
part I:
One, trial target: the whitening skin and preserving moisture eye cream that embodiment 1 prepares.
Two, tested crowd
Sex number: female, 40 people.
Age: between 30 ~ 55 years old.
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Three, method of testing: adopt the skin elasticity CotometerMPA580 main frame that German Courage+Khazaka company manufactures, the probe used is ReviscometerRV600 elastic fibrous tissue test probe, surveys and averages for five times.Test zone: skin around the eyes.First measure the blank value (R2, R5, R7) of 20min after tested region clean, then specify that experimenter adheres to using above-mentioned trial target every day sooner or later, test test zone skin elasticity index R2, R5, R7 value (in test process, negative pressure is constant is 450mbar) after 1 week, 2 weeks, 3 weeks, 4 weeks respectively.
Index illustrates: skin elasticity index R2, R5, R7 are more close to 1, and the elasticity of skin is better.
R2=Ua/Uf;R5=Ur/Ue;R7=Ur/Uf
Uf---skin maximum tension amount
Ue---constant negative pressure is added to after on skin, the amount of tension of skin during 0.1 second, positioning elastic part amount of tension.
Ur---cancel after negative pressure, skin will restore to the original state rapidly state, is divided into elastic score value Ur equally, namely cancels negative pressure after 0.1 second, the recovery value of skin and visco-elastic portions value, or claim plastic value.
Ua---from cancelling the recovery value of negative pressure to skin when follow-on test skin surface adds negative pressure more next time.
Four, test result is as following table 1.
Table 1 embodiment 1 whitening skin and preserving moisture eye cream table with test results
From upper table 1: use whitening skin and preserving moisture eye cream first week rear R2, R5, R7 of embodiment 1 to increase to some extent, within 4th week, R2, R5, R7 all rise obviously, and R2, R5, R7 value levels off to 1, the skin elasticity index of experimenter has very large lifting, as can be seen here, this whitening skin and preserving moisture eye cream has increases skin elasticity, antidotal effect.
part II:
One, trial target: embodiment 1 ~ 3, eye cream prepared by comparative example one, two.
Two, tested crowd
Sex number: female, 100 people.
Age: between 38 ~ 55 years old.
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 5 groups, often organize 20 people, 40 ± 2 years old mean age.
Three, method of testing: respectively use-case 1 ~ 3, eye cream prepared by comparative example one, two, observes and experiences result of use.Using method: after experimenter cleans face, get the eye cream of a meter great little, dub in eye all around, with refer to abdomen along near the eyes gently bullet clap until thoroughly absorb, the every day of each use sooner or later once, adhere to use one month, at least check weekly once to understand with or without whole body and local untoward reaction, and itemized record result.
Four, testing evaluation result is as follows:
(one month) on probation feedback conclusive table of table 2 embodiment 1 whitening skin and preserving moisture eye cream
(one month) on probation feedback conclusive table of table 3 embodiment 2 whitening skin and preserving moisture eye cream
(one month) on probation feedback conclusive table of table 4 embodiment 3 whitening skin and preserving moisture eye cream
(one month) on probation feedback conclusive table of table 5 comparative example one eye cream
(one month) on probation feedback conclusive table of table 6 comparative example two eye cream
(1) from upper table 2 ~ 4, whitening skin and preserving moisture eye cream the liking and approving extensively by experimenter of the embodiment of the present invention 1 ~ 3, experimenter all represents whitening skin and preserving moisture eye cream good penetrability of the present invention, easy absorption, degree of depth whitening skin and preserving moisture, uses rear skin around the eyes salubrious not sticky, effectively calms down microgroove, reduce dry stricture of vagina and wrinkle, and effectively improve drying, relaxation, skin beauty water is moistened smooth, high resilience, wherein the highest with the degree of recognition of embodiment 1, therefore embodiment 1 is preferred embodiment.
(2) from upper table 5 ~ 6, comparative example one and comparative example two eye cream all lack some component in whitening skin and preserving moisture eye cream formula of the present invention, its result of use is all not as embodiment 1 ~ 3, illustrate that whitening skin and preserving moisture eye cream formula of the present invention is not obtained by the simple combination of each component, then further illustrate between each component of formula of the present invention and there is synergism.
There is not people to occur allergic phenomena in whole experimenter simultaneously, all do not occur the situations such as skin pruritus, twinge, redness yet.Therefore, the gentle safety of whitening skin and preserving moisture eye cream of the present invention, can life-time service.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.
Claims (9)
1. a whitening skin and preserving moisture eye cream, it is characterized in that, be made up of the component of following parts by weight: 2 ~ 6 parts, vaseline, hydroxyethyl-cellulose 0.5 ~ 2 part, glycerol 3 ~ 8 parts, butanediol 2 ~ 5 parts, polydimethylsiloxane 2 ~ 5 parts, Oleum Cocois 1.5 ~ 3 parts, cetearyl alcohol 1 ~ 3 part, sorbitol 0.5 ~ 2 part, vitamin E 0.5 ~ 2 part, Glucate SS 0.3 ~ 1.5 part, Cortex Eucommiae extract 6 ~ 12 parts, Semen Coicis extract 3 ~ 8 parts, Aloe extract 3 ~ 8 parts, Margarita powder 2 ~ 6 parts, roe elite 2 ~ 6 parts, milk protein 1 ~ 3 part, carbomer 0.05 ~ 0.5 part, diethanolamine 0.05 ~ 0.5 part, tranexamic acid 0.1 ~ 0.5 part, cithrol 0.002 ~ 0.1 part, 0.003 ~ 0.03 part, essence, antiseptic 0.01 ~ 0.2 part and 60 ~ 70 parts, water.
2. whitening skin and preserving moisture eye cream as claimed in claim 1, it is characterized in that, be made up of the component of following parts by weight: 2 parts, vaseline, hydroxyethyl-cellulose 0.5 part, glycerol 3 parts, butanediol 2 parts, polydimethylsiloxane 2 parts, Oleum Cocois 1.5 parts, cetearyl alcohol 1 part, sorbitol 0.5 part, vitamin E 0.5 part, Glucate SS 0.3 part, Cortex Eucommiae extract 6 parts, Semen Coicis extract 3 parts, Aloe extract 3 parts, Margarita powder 2 parts, roe elite 2 parts, milk protein 1 part, carbomer 0.05 part, diethanolamine 0.05 part, tranexamic acid 0.1 part, cithrol 0.002 part, 0.003 part, essence, antiseptic 0.01 part and 60 parts, water.
3. whitening skin and preserving moisture eye cream as claimed in claim 1, it is characterized in that, be made up of the component of following parts by weight: 6 parts, vaseline, hydroxyethyl-cellulose 2 parts, glycerol 8 parts, butanediol 5 parts, polydimethylsiloxane 5 parts, Oleum Cocois 3 parts, cetearyl alcohol 3 parts, sorbitol 2 parts, vitamin E2 part, Glucate SS 1.5 parts, Cortex Eucommiae extract 12 parts, Semen Coicis extract 8 parts, Aloe extract 8 parts, Margarita powder 6 parts, roe elite 6 parts, milk protein 3 parts, carbomer 0.5 part, diethanolamine 0.5 part, tranexamic acid 0.5 part, cithrol 0.1 part, 0.03 part, essence, antiseptic 0.2 part and 70 parts, water.
4. whitening skin and preserving moisture eye cream as claimed in claim 1, it is characterized in that, be made up of the component of following parts by weight: 4 parts, vaseline, hydroxyethyl-cellulose 1 part, glycerol 6 parts, butanediol 3 parts, polydimethylsiloxane 3 parts, Oleum Cocois 2 parts, cetearyl alcohol 2 parts, sorbitol 1 part, vitamin e1 part, Glucate SS 1 part, Cortex Eucommiae extract 9 parts, Semen Coicis extract 6 parts, Aloe extract 6 parts, Margarita powder 4 parts, roe elite 4 parts, milk protein 2 parts, carbomer 0.3 part, diethanolamine 0.3 part, tranexamic acid 0.3 part, cithrol 0.05 part, 0.05 part, essence, antiseptic 0.1 part and 65 parts, water.
5. the whitening skin and preserving moisture eye cream as described in any one of claim 1 ~ 4, is characterized in that, described antiseptic is made up of according to the weight ratio of 2:1 methyl hydroxybenzoate and propyl hydroxybenzoate.
6. the whitening skin and preserving moisture eye cream as described in any one of claim 1 ~ 4, is characterized in that, described Cortex Eucommiae extract is obtained by following steps:
S1: get the Cortex Eucommiae, drying and crushing, add the water soaking 45 ~ 60 minutes of medical material gross weight 5 ~ 12 times amount, reflux, extract, 1 ~ 3 time, each 4 ~ 9 hours, filters and retains filtering residue, merging filtrate, obtaining Aqueous extracts;
S2: adding medical material gross weight 5 ~ 12 times amount volume fraction in the filtering residue in S1 is the ethanol of 75 ~ 85%, reflux, extract, 2 ~ 3 times, each 3 ~ 8 hours, filter, merging filtrate, obtains alcohol extract;
S3: merge Aqueous extracts and alcohol extract, after stirring, leaves standstill 12 ~ 24 hours, centrifugal 10 ~ 15 minutes of 2000g, gets supernatant, carries out hyperfiltration treatment, temperature is 25 ~ 40 DEG C, material liquid pH is 6 ~ 8, and inlet pressure is 0.3MPa, the low 0.35kPa of liquid outlet pressure ratio inlet pressure, the pressure wave moment of periodic pressure fluctuation is 0.15 ~ 0.25MPa, when feed liquid stock solution reduces 1/8 ~ 1/4, then the ultrafiltration 1 ~ 2 time that adds water, merge ultrafiltrate; Obtain described Cortex Eucommiae extract.
7. the whitening skin and preserving moisture eye cream as described in any one of claim 1 ~ 4, it is characterized in that, described Semen Coicis extract is obtained by following steps: get Semen Coicis and clean, crushed after being dried, cross 100 ~ 200 mesh sieves, adding Semen Coicis coarse powder weight 6 ~ 15 times amount volume fraction is the ethanol of 70 ~ 85%, soak 7 ~ 12 hours, supersound extraction 2 times at 45 ~ 60 DEG C, each 35 ~ 60 minutes, supersonic frequency was 15 ~ 30kHz, filter, merging filtrate, during filtrate reduced in volume to 55 DEG C, relative density is the clear paste of 1.15 ~ 1.25, obtains Semen Coicis extract.
8. the whitening skin and preserving moisture eye cream as described in any one of claim 1 ~ 4, is characterized in that, described Aloe extract is obtained by following steps:
S1: get Aloe, cleans, and after drying, is squeezed obtain Aloe mixing juice with squeezer;
S2: the Aloe obtained mixing juice is put in filtering tank, removes impurity, obtain Aloe original juice;
S3: put in vacuum-concentrcted device by Aloe original juice liquid and concentrate, concentrated 2 ~ 3 times of circulation, obtains Aloe extract.
9. the preparation method of the whitening skin and preserving moisture eye cream as described in any one of claim 1 ~ 8, is characterized in that, comprise the following steps:
S1: hydroxyethyl-cellulose, Glucate SS, cetearyl alcohol, vaseline, polydimethylsiloxane, Oleum Cocois and antiseptic are placed in oil phase pot, stirs and is heated to 70 ~ 85 DEG C, being stirred to material and dissolving completely, obtain material A;
S2: put into the water of 1/2 in main cooker, opens homogenizing, is slowly sprinkled into by carbomer, stirring and dissolving evenly after by glycerol, sorbitol, butanediol, vitamin E and 1/2 water add in main cooker, be stirred to evenly, be heated to 70 ~ 85 DEG C, insulation 5 ~ 10min;
S3: by material A suction main cooker, then add diethanolamine, open homogenizing, homogenizing 3 ~ 8min, obtains material B, and material B carries out insulation froth breaking;
S4: be cooled to 35 ~ 45 DEG C after material B bubble-free, add after tranexamic acid is molten in advance, add Cortex Eucommiae extract, Semen Coicis extract, Aloe extract, Margarita powder, roe elite, milk protein and essence again, be stirred to evenly, finally add cithrol solvent in advance, be stirred to evenly, namely discharging obtains whitening skin and preserving moisture eye cream.
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CN106137867A (en) * | 2016-08-24 | 2016-11-23 | 秦艳红 | A kind of moisturizing eye cream |
CN106580792A (en) * | 2016-12-24 | 2017-04-26 | 严志海 | Whitening facial cream and preparation method thereof |
CN106821922A (en) * | 2016-11-26 | 2017-06-13 | 无锡市汉方八珍科技有限公司 | A kind of roe Essence and preparation method thereof |
CN108785226A (en) * | 2018-06-06 | 2018-11-13 | 广东巴松那生物科技有限公司 | It is a kind of to highlight the color eye essence and preparation method thereof of eye god |
CN109692137A (en) * | 2017-10-20 | 2019-04-30 | 陈静 | A kind of moisturizing emulsion and preparation method thereof |
CN112603846A (en) * | 2021-01-07 | 2021-04-06 | 上海南滨江细胞生物科技有限公司 | Preparation method of eye cream of autologous adipose-derived stem cell cytokine extracting solution |
CN113827538A (en) * | 2021-10-11 | 2021-12-24 | 英德市东顺精细化工实业有限公司 | Roe essence repair cream and preparation process thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040166170A1 (en) * | 2003-02-26 | 2004-08-26 | Hunter Gary L. | Method for therapeutically treating mammals |
CN104546630A (en) * | 2013-10-22 | 2015-04-29 | 罗鹏程 | Wrinkle-removing moisturizing efficient eye cream and preparation method thereof |
CN104958231A (en) * | 2015-06-29 | 2015-10-07 | 济南正骐生物科技有限公司 | Black eye removing eye cream |
-
2015
- 2015-11-18 CN CN201510799232.2A patent/CN105287340B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040166170A1 (en) * | 2003-02-26 | 2004-08-26 | Hunter Gary L. | Method for therapeutically treating mammals |
CN104546630A (en) * | 2013-10-22 | 2015-04-29 | 罗鹏程 | Wrinkle-removing moisturizing efficient eye cream and preparation method thereof |
CN104958231A (en) * | 2015-06-29 | 2015-10-07 | 济南正骐生物科技有限公司 | Black eye removing eye cream |
Non-Patent Citations (3)
Title |
---|
刘雅娟: "《女性饮食营养全书》", 31 January 2012, 吉林科学技术出版社 * |
王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
采薇: "《天然美肤面膜300例》", 31 July 2012, 中国纺织出版社 * |
Cited By (7)
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CN106137867A (en) * | 2016-08-24 | 2016-11-23 | 秦艳红 | A kind of moisturizing eye cream |
CN106821922A (en) * | 2016-11-26 | 2017-06-13 | 无锡市汉方八珍科技有限公司 | A kind of roe Essence and preparation method thereof |
CN106580792A (en) * | 2016-12-24 | 2017-04-26 | 严志海 | Whitening facial cream and preparation method thereof |
CN109692137A (en) * | 2017-10-20 | 2019-04-30 | 陈静 | A kind of moisturizing emulsion and preparation method thereof |
CN108785226A (en) * | 2018-06-06 | 2018-11-13 | 广东巴松那生物科技有限公司 | It is a kind of to highlight the color eye essence and preparation method thereof of eye god |
CN112603846A (en) * | 2021-01-07 | 2021-04-06 | 上海南滨江细胞生物科技有限公司 | Preparation method of eye cream of autologous adipose-derived stem cell cytokine extracting solution |
CN113827538A (en) * | 2021-10-11 | 2021-12-24 | 英德市东顺精细化工实业有限公司 | Roe essence repair cream and preparation process thereof |
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