CN108403250A - Livestock body surface insect-repelling method - Google Patents
Livestock body surface insect-repelling method Download PDFInfo
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- CN108403250A CN108403250A CN201810101116.2A CN201810101116A CN108403250A CN 108403250 A CN108403250 A CN 108403250A CN 201810101116 A CN201810101116 A CN 201810101116A CN 108403250 A CN108403250 A CN 108403250A
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- body surface
- livestock body
- repelling method
- livestock
- bentonite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/40—Heating or cooling means; Combinations thereof
- A61J2200/42—Heating means
Abstract
The invention discloses a kind of livestock body surface insect-repelling method, the livestock body surface insect-repelling method is:Liquid medicine is sprayed to the livestock body surface, wherein the liquid medicine is prepared by the following method and obtains:Including:1)Chinese herbal medicine, ethyl alcohol and ethyl acetate are decocted, then filter to take filtrate so that extracting solution is made;2)Under ultrasound condition, extracting solution, nano-bentonite, rotenone, Albendazole are subjected to adsorption treatment, then filtered so that modified Nano bentonite is made;3)Modified Nano bentonite, cyclodextrin and water are subjected to ultrasonic vibration so that liquid medicine is made;Wherein, Chinese herbal medicine is azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and cacumen biotae.The livestock body surface insect-repelling method has excellent anthelminthic effect, and milder, nuisanceless to environment and livestock.
Description
Technical field
The present invention relates to a kind of livestock body surface insect-repelling methods.
Background technology
Animal husbandry refer to herd, stable breeding or the two combine mode, raising livestock and poultry to obtain animal product or the draught animal
Production division.It include livestock raise herd, home poultry raising, economic beasts are raised and train.Animal husbandry has important in national economy
Status and effect, predominantly:1. providing the animal foods such as meat, milk, eggs;2. for industry provide wool, cashmere, skin,
The raw materials such as hair on the neck, beast bone, casing;3. exporting acquisition of foreign currency by livestock products;4. the industry of animal husbandry input and livestock products is promoted to add
Industrial expansion increases labour employment chance;5. providing organic fertilizer for production estimation;6. increasing farmers' income;7. being agriculture
Industry and transportation provide animal power;8. promoting the economy and cultural development in vast pastoral area, strengthen the unity among nationalities.Thus
As it can be seen that the development of country is to be unable to do without the support of animal husbandry.
During developing animal husbandry, often need to livestock carry out expelling parasite processing, wherein be divided into internal expelling parasite and
Body surface area worm.Currently, body surface area worm is generally to carry out expelling parasite using chemically synthesized organic reagent, although can obtain certain
Anthelminthic effect;But on the one hand the health of livestock can be adversely affected by being chemical synthesis reagent, and then affect domestic animal
The meat and pelage quality of poultry, the chemically synthesized reagent of another aspect can cause environmental pollution.
Invention content
The object of the present invention is to provide a kind of livestock body surface insect-repelling method, which has excellent drive
Worm effect, and it is milder, nuisanceless to environment and livestock.
To achieve the goals above, the present invention provides a kind of livestock body surface insect-repelling method, livestock body surface expelling parasite sides
Method is:Liquid medicine is sprayed to the livestock body surface, wherein the liquid medicine is prepared by the following method and obtains:
1)Chinese herbal medicine, ethyl alcohol and ethyl acetate are decocted, then filter to take filtrate so that extracting solution is made;
2)Under ultrasound condition, extracting solution, nano-bentonite, rotenone, Albendazole are subjected to adsorption treatment, then filtered
Modified Nano bentonite is made;
3)Modified Nano bentonite, cyclodextrin and water are subjected to ultrasonic vibration so that liquid medicine is made;
Wherein, Chinese herbal medicine is azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and cacumen biotae.
In the above-mentioned technical solutions, the present invention passes through first by the mixed liquor of ethyl alcohol and ethyl acetate composition to Chinese herbal medicine
Decoct and then obtains extracting solution;Then, extracting solution, rotenone, Albendazole are adsorbed by nano-bentonite
And then modified Nano bentonite is made;Then, modified Nano bentonite is coated by cyclodextrin, while utilizes cyclodextrin
Outer rim is hydrophilic and characteristic that inner cavity is hydrophobic so as to soluble in water and then liquid medicine for livestock body surface expelling parasite is made.It should
Livestock body surface insect-repelling method carries out livestock using the liquid medicine and carries out body surface expelling parasite, has an excellent anthelminthic effect, and to environment and
Livestock is milder, nuisanceless.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Specific implementation mode
The specific implementation mode of the present invention is described in detail below.It should be understood that described herein specific
Embodiment is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
The present invention provides a kind of livestock body surface insect-repelling method, the livestock body surface insect-repelling method is:By liquid medicine to described
Livestock body surface sprays, wherein the liquid medicine is prepared by the following method and obtains:
1)Chinese herbal medicine, ethyl alcohol and ethyl acetate are decocted, then filter to take filtrate so that extracting solution is made;
2)Under ultrasound condition, extracting solution, nano-bentonite, rotenone, Albendazole are subjected to adsorption treatment, then filtered
Modified Nano bentonite is made;
3)Modified Nano bentonite, cyclodextrin and water are subjected to ultrasonic vibration so that liquid medicine is made;
Wherein, Chinese herbal medicine is azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and cacumen biotae.
In the step 1 of the present invention)In, the dosage of each material can select in a wide range, but in order to make the livestock
Body surface insect-repelling method has superior anthelminthic effect and mildness, it is preferable that in step 1)In, Chinese herbal medicine, ethyl alcohol and second
The weight ratio of acetoacetic ester is 10:35-45:10-15;In Chinese herbal medicine, azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali,
The weight ratio of buckeye and cacumen biotae is 10:5-8:15-20:8-12:3-6:10-12:8-15.
In the step 1 of the present invention)In, the condition of decoction can select in a wide range, but in order to make the livestock body
Table insect-repelling method has superior anthelminthic effect and mildness, it is preferable that decoction meets the following conditions:Decocting temperature is
79-83 DEG C, decocting time 2-4h.
In the step 2 of the present invention)In, the dosage of each substance can select in a wide range, but in order to make the livestock
Body surface insect-repelling method has superior anthelminthic effect and mildness, it is preferable that in step 2)In, extracting solution, nanometer swelling
Soil, rotenone, Albendazole weight ratio be 100:30-40:5-8:2-6.
In the step 2 of the present invention)In, the condition of adsorption treatment can select in a wide range, but in order to make the domestic animal
Carcass table insect-repelling method has superior anthelminthic effect and mildness, it is preferable that in step 2)In, adsorption treatment meet with
Lower condition:Treatment temperature is 40-50 DEG C, processing time 6-8h, supersonic frequency 25-30KHz.
In the step 3 of the present invention)In, the dosage of each substance can select in a wide range, but in order to make the livestock
Body surface insect-repelling method has superior anthelminthic effect and mildness, it is preferable that in step 3)In, modified Nano bentonite,
The weight ratio of cyclodextrin and water is 10:4-6:200-220.
In the step 3 of the present invention)In, the condition of ultrasonic vibration can select in a wide range, but in order to make the domestic animal
Carcass table insect-repelling method has superior anthelminthic effect and mildness, it is preferable that in step 3)In, ultrasonic vibration meet with
Lower condition:It is 15-35 DEG C to shake temperature, and the concussion time is 3-5h, supersonic frequency 35-40KHz.
In the present invention, the average grain diameter of nano-bentonite can select in a wide range, but in order to make the livestock
Body surface insect-repelling method has superior anthelminthic effect and mildness, it is preferable that the average grain diameter of nano-bentonite is 15-
30nm。
In the present invention, the sprinkling frequency of liquid medicine can select in a wide range, but in order to make the livestock body surface drive
Worm method has superior anthelminthic effect, it is preferable that the sprinkling frequency of the liquid medicine is 3-5 times/day, monthly sprays a week
Phase, a cycle are 5-7 days.
In the present invention, the fountain height of liquid medicine can select in a wide range, but in order to make the livestock body surface expelling parasite
Method has superior anthelminthic effect, it is preferable that on the basis of the livestock of 100kg, the fountain height of each liquid medicine is 30-
50mL。
The present invention will be described in detail by way of examples below.
Embodiment 1
1)By Chinese herbal medicine(Azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and the weight ratio of cacumen biotae are 10:
7:35:10:5:11:12), ethyl alcohol and ethyl acetate is according to 10:40:13 weight ratio is decocted(It is 80 DEG C to decoct temperature, is decocted
It is 3h to boil the time), filtrate is then filtered to take so that extracting solution is made;
2)Under ultrasound condition, by extracting solution, nano-bentonite(Average grain diameter is 20nm), rotenone, Albendazole according to
100:35:7:4 weight ratio carries out adsorption treatment(Treatment temperature is 45 DEG C, processing time 7h, supersonic frequency 28KHz),
Then it filters so that modified Nano bentonite is made;
3)By modified Nano bentonite, cyclodextrin and water according to 10:5:200 weight ratio carries out ultrasonic vibration(Shaking temperature is
25 DEG C, the concussion time is 4h, supersonic frequency 38KHz)The liquid medicine A1 for livestock body surface expelling parasite is made.
Embodiment 2
1)By Chinese herbal medicine(Azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and the weight ratio of cacumen biotae are 10:
5:15:8:3:10:8), ethyl alcohol and ethyl acetate is according to 10:35:10 weight ratio is decocted(It is 79 DEG C to decoct temperature, is decocted
Time is 2h), filtrate is then filtered to take so that extracting solution is made;
2)Under ultrasound condition, by extracting solution, nano-bentonite(Average grain diameter is 15nm), rotenone, Albendazole according to
100:30:5:2 weight ratio carries out adsorption treatment(Treatment temperature is 40 DEG C, processing time 6h, supersonic frequency 25KHz),
Then it filters so that modified Nano bentonite is made;
3)By modified Nano bentonite, cyclodextrin and water according to 10:4:210 weight ratio carries out ultrasonic vibration(Shaking temperature is
15 DEG C, the concussion time is 3h, supersonic frequency 35KHz)The liquid medicine A2 for livestock body surface expelling parasite is made.
Embodiment 3
1)By Chinese herbal medicine(Azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and the weight ratio of cacumen biotae are 10:
8:20:12:6:12:15), ethyl alcohol and ethyl acetate is according to 10:45:15 weight ratio is decocted(It is 83 DEG C to decoct temperature, is decocted
It is 4h to boil the time), filtrate is then filtered to take so that extracting solution is made;
2)Under ultrasound condition, by extracting solution, nano-bentonite(Average grain diameter is 30nm), rotenone, Albendazole according to
100:40:8:6 weight ratio carries out adsorption treatment(Treatment temperature is 50 DEG C, processing time 8h, supersonic frequency 30KHz),
Then it filters so that modified Nano bentonite is made;
3)By modified Nano bentonite, cyclodextrin and water according to 10:6:250 weight ratio carries out ultrasonic vibration(Shaking temperature is
35 DEG C, the concussion time is 5h, supersonic frequency 40KHz)The liquid medicine A3 for livestock body surface expelling parasite is made.
Comparative example 1
It carries out that liquid medicine B1 is made according to the method for embodiment 1, unlike, step 2)Extracting solution is not used.
Comparative example 2
It carries out that liquid medicine B2 is made according to the method for embodiment 1, unlike, step 3)Cyclodextrin is not used.
Application examples 1
The ox for choosing six weight 500kg or so is experimental subjects, detects the jump of the body surface of ox by sampling method before the experiments
Then flea density 1 periodically sprinkles above-mentioned liquid medicine(The sprinkling frequency of liquid medicine is 4 times/day, monthly sprays a cycle, a week
Phase is 6 days, and the fountain height of liquid medicine is 40mL), the flea density 2 of the body surface of ox is detected after one month;Wherein, blank control group is sprayed
Watering;Concrete outcome is shown in Table 1.
Table 1
The substance of sprinkling | Flea density 1(Only/dm2) | Flea density 2(Only/dm2) |
A1 | 8 | 0 |
A2 | 10 | 0 |
A3 | 12 | 0 |
B1 | 15 | 65 |
B2 | 13 | 38 |
Water | 9 | 122 |
The preferred embodiment of the present invention has been described above in detail, still, the tool during present invention is not limited to the embodiments described above
Body details can carry out a variety of simple variants, these letters to technical scheme of the present invention within the scope of the technical concept of the present invention
Monotropic type all belongs to the scope of protection of the present invention.
It is further to note that specific technical features described in the above specific embodiments, in not lance
In the case of shield, can be combined by any suitable means, in order to avoid unnecessary repetition, the present invention to it is various can
The combination of energy no longer separately illustrates.
In addition, various embodiments of the present invention can be combined randomly, as long as it is without prejudice to originally
The thought of invention, it should also be regarded as the disclosure of the present invention.
Claims (10)
1. a kind of livestock body surface insect-repelling method, which is characterized in that the livestock body surface insect-repelling method is:By liquid medicine to the livestock
Body surface sprays, wherein the liquid medicine is prepared by the following method and obtains:
1)Chinese herbal medicine, ethyl alcohol and ethyl acetate are decocted, then filter to take filtrate so that extracting solution is made;
2)Under ultrasound condition, the extracting solution, nano-bentonite, rotenone, Albendazole are subjected to adsorption treatment, then
Filtering is to be made modified Nano bentonite;
3)The modified Nano bentonite, cyclodextrin and water are subjected to ultrasonic vibration so that liquid medicine is made;
Wherein, the Chinese herbal medicine is azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, raw Radix Astragali, buckeye and cacumen biotae.
2. livestock body surface insect-repelling method according to claim 1, wherein in step 1)In, the Chinese herbal medicine, ethyl alcohol and second
The weight ratio of acetoacetic ester is 10:35-45:10-15;
In the Chinese herbal medicine, the azedarach, radix ranunculi ternati, manyleaf meadowure rhizome and root, semen momordicae, the weight for giving birth to Radix Astragali, buckeye and cacumen biotae
Amount is than being 10:5-8:15-20:8-12:3-6:10-12:8-15.
3. livestock body surface insect-repelling method according to claim 1, wherein the decoction meets the following conditions:Decoct temperature
It is 79-83 DEG C, decocting time 2-4h.
4. the livestock body surface insect-repelling method according to any one of claim 1-3, wherein in step 2)In, it is described to carry
Take liquid, nano-bentonite, rotenone, Albendazole weight ratio be 100:30-40:5-8:2-6.
5. livestock body surface insect-repelling method according to claim 4, wherein in step 2)In, the adsorption treatment meet with
Lower condition:Treatment temperature is 40-50 DEG C, processing time 6-8h, supersonic frequency 25-30KHz.
6. the livestock body surface insect-repelling method according to claim 1-3, any one of 5, wherein in step 3)In, it is described
The weight ratio of modified Nano bentonite, cyclodextrin and water is 10:4-6:200-220.
7. the livestock body surface insect-repelling method according to claim 1-3, any one of 5, wherein in step 3)In, it is described
Ultrasonic vibration meets the following conditions:It is 15-35 DEG C to shake temperature, and the concussion time is 3-5h, supersonic frequency 35-40KHz.
8. the livestock body surface insect-repelling method according to claim 1-3, any one of 5, wherein the nano-bentonite
Average grain diameter is 15-30nm.
9. the livestock body surface insect-repelling method according to claim 1-3, any one of 5, wherein the sprinkling frequency of the liquid medicine
Rate is 3-5 times/day, monthly sprays a cycle, and a cycle is 5-7 days.
10. livestock body surface insect-repelling method according to claim 9, wherein on the basis of the livestock of 100kg, each liquid medicine
Fountain height be 30-50mL.
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CN106377656A (en) * | 2016-10-21 | 2017-02-08 | 江西正邦动物保健品有限公司 | Traditional Chinese medicine pre-mixing agent for expelling parasites and preparation method thereof |
CN106490026A (en) * | 2016-10-31 | 2017-03-15 | 郑州思辩科技有限公司 | A kind of storage pest insecticide and preparation method thereof |
CN106857726A (en) * | 2017-01-23 | 2017-06-20 | 嵊州市派特普科技开发有限公司 | Pure natural insecticide and preparation method thereof |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN102100661A (en) * | 2009-12-17 | 2011-06-22 | 苏州知微堂生物科技有限公司 | Process for preparing novel formulation of integrative traditional Chinese medicine and production method thereof |
CN101732336A (en) * | 2009-12-18 | 2010-06-16 | 华中师范大学 | Antiparasitic solution for external use |
CN103341053A (en) * | 2013-07-26 | 2013-10-09 | 广东药学院 | Purification method for large ligusticum wallichii oral liquid |
CN105418217A (en) * | 2015-11-27 | 2016-03-23 | 颍上县永祥旱粮研究所 | Corn compound fertilizer with slow-release and insect-resistant effects |
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CN106490026A (en) * | 2016-10-31 | 2017-03-15 | 郑州思辩科技有限公司 | A kind of storage pest insecticide and preparation method thereof |
CN106857726A (en) * | 2017-01-23 | 2017-06-20 | 嵊州市派特普科技开发有限公司 | Pure natural insecticide and preparation method thereof |
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