CN108379107B - Composition with effects of moisturizing, whitening, removing yellow and preventing allergy and preparation method thereof - Google Patents

Composition with effects of moisturizing, whitening, removing yellow and preventing allergy and preparation method thereof Download PDF

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CN108379107B
CN108379107B CN201810341307.6A CN201810341307A CN108379107B CN 108379107 B CN108379107 B CN 108379107B CN 201810341307 A CN201810341307 A CN 201810341307A CN 108379107 B CN108379107 B CN 108379107B
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潘丽媛
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Wuchi Zhuhai Daily Chemical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention discloses a composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which comprises the following components in percentage by weight: bioactive polypeptide 0.002-0.5%, glabridin 3-8%, matrix component 16-38%, and cold spring water for the rest. The invention inhibits the formation of melanin from the skin source, and has the effects of moisturizing, whitening, removing yellow, fading color spots and making the skin tender and fair; the added cold spring water of the Wudalianchi volcano is rich in trace elements such as potassium, sodium, calcium, magnesium, iron, manganese, fluorine, chromium, zinc, copper, barium and the like, and the content of the trace elements is equivalent to the proportion required by a human body, so that the cold spring water can effectively regulate the digestive function and the water and salt metabolism of the human body, can improve the functions of a biological enzyme system and an endocrine system of the human body, has good medicinal value and has good curative effect on skin diseases; the skin care product is suitable for general people, people with sensitive skin or skin diseases, and can further improve the skin diseases.

Description

Composition with effects of moisturizing, whitening, removing yellow and preventing allergy and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a composition with the effects of moisturizing, whitening, removing yellow and preventing allergy and a preparation method thereof, namely a skin care product comprising the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy.
Background
With the increasing of age and working pressure, the radiation of electronic products is increased and the surrounding environment is polluted, after a certain age, the grease and collagen of skin and skin are lost, and the aging is gradually aggravated, so that the problems of fine lines, looseness, dark yellow and pigmentation and the like can occur on the face. Therefore, skin care products having the functions of moisturizing, whitening and removing yellow are favored by many female friends for the purpose of beauty.
Most of the skin care products in the current market have the effects of moisturizing and moisturizing, and people with skin allergy or skin diseases cannot directly use the skin care products. In the using process, the skin care products have certain irritation to the skin, can cause skin allergy, cannot play the role of skin care, and even have opposite side effects. Therefore, there is a need to develop a skin care product with the effects of moisturizing, whitening, removing yellow and preventing allergy, so that people with skin allergy can normally use the skin care product, and the allergic condition of allergic skin can be further improved after the skin care product is used.
Disclosure of Invention
The invention aims to provide a composition with good moisturizing, whitening and yellow-dispelling effects, which is not only suitable for general people, but also suitable for skin allergy patients, and can further improve the allergic conditions of allergic skin after use.
The technical scheme adopted by the invention is as follows: the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.002-1.0% of bioactive polypeptide,
3 to 10 percent of glabridin,
16 to 38 percent of matrix component,
the balance of cold spring water.
Preferably, the bioactive polypeptide is selected from one or more of carnosine, palmitoyl tripeptide-1, palmitoyl tripeptide-3, palmitoyl tetrapeptide-7 and hexapeptide.
Preferably, the bioactive polypeptide consists of the following components in percentage by weight based on the total weight of the composition: 0.0002-0.2% carnosine, 0.0005-0.2% palmitoyl tripeptide-1, 0.001-0.2% palmitoyl tripeptide-3, 0.0002-0.2% palmitoyl tetrapeptide-7, and 0.0001-0.2% hexapeptide.
The palmitoyl tripeptide-1 has strong lipid solubility, can be better absorbed by the skin, enhances the facial elasticity, promotes the cell activity, improves the water content of the skin, improves the skin color, and has obvious regulation and promotion effects on the renewal and repair of skin cells and the synthesis of collagen. The efficacy of the sanshengtai can achieve the beautifying effect of collagen injection.
Palmitoyl tetrapeptide-7 can be used in cosmetic product for inhibiting the production of excessive interleukin. This cytokine triggers an acute inflammatory response in the body, resulting in impaired glycosylation, i.e., impaired cross-linking and binding of glucose and proteins, hardening of the tissue, and adversely affecting the skin's supporting system, such as collagen, elastin and other proteins, resulting in wrinkles, laxity and uneven skin tone. The palmitoyl tetrapeptide-7 is easy to be absorbed by the skin, has the effects of eliminating the potential inflammation of the skin and resisting allergy, has remarkable effects of reducing the generation of wrinkles and recovering the vitality of the skin, can promote the growth of connective tissues and increase the generation of collagen in the skin, and when the collagen is increased, the sanshengtai and the sishengtai are used in combination, so that the synthesis of the collagen and the hyaluronic acid in fibroblasts can be effectively promoted, and the effects of resisting wrinkles, diminishing inflammation and resisting allergy are remarkable.
The hexapeptide is a core component of top-grade skin care products, is a bioactive polypeptide, and can reduce existing facial wrinkles and effectively prevent new wrinkles. The hexapeptide can slow down the force of muscle contraction, relax muscles, reduce the generation of dynamic lines, eliminate fine lines, effectively reorganize the elasticity of collagen, increase the activity of elastin, loosen facial lines, smooth wrinkles and improve relaxation. The hexapeptide is used as an anti-wrinkle component in cosmetics, and has an excellent effect.
The hexapeptide is a botulinum toxin-like component, has all functions of botulinum toxin, does not contain any toxicity, and is a non-toxic substance. The main component of the product is a biochemical product formed by arranging and combining six amino acids, although the biochemical product is usually compared with the botulinum, the mechanism of the biochemical product is completely different. The hexapeptide can intercept signals of muscle contraction, reduce the force of muscle contraction and further improve the depth and the length of fine wrinkles. It has become an attractive new beauty pet to replace botulinum toxin.
The glycation of the skin means that excessive sugar is released in blood in the whole day due to the fact that the skin metabolizes too slowly, the excessive sugar is attached to collagen, the collagen is broken or disordered, and wrinkles and roughness appear on the skin. Mashing appears as a white dough that is baked to turn into a yellow bread, a process by which the dough is mashed and sweet to eat. As a rule for the skin, glycation can darken the skin. Carnosine can enhance the skin's natural defenses against heat and sunlight attack, against free radicals and glycation reactions, against skin oxidation and saccharide production, and protect cells from UV damage.
Preferably, the matrix component is selected from one or more of butanediol, sodium hyaluronate and glycerol polymethacrylate.
Preferably, the matrix component consists of the following components in percentage by weight, based on the total weight of the composition: 2-8% of butanediol, 8-15% of sodium hyaluronate and 6-15% of glycerol polymethacrylate.
Preferably, the cold spring water is Wudalianchi volcano cold spring water, the pH value of the cold spring water is 6.5-7.5, and the contents of trace elements are as follows: 75-90mg/L of potassium, 0.1-0.5mg/L of iron, 60-75mg/L of sodium, 0.06-0.07 mg/L of cobalt, 75-90mg/L of magnesium, 0.01-0.016mg/L of iodine, 95-110mg/L of calcium, 0.001-0.002mg/L of selenium, 0.06-0.08mg/L of zinc, 65-75mg/L of metasilicic acid, 0.02-0.05mg/L of lithium, 1300 mg/L of carbon dioxide and 1600mg/L of sodium and 1.01-1.30mg/L of strontium.
Most of skin care products common in the market at present only have the effects of moisturizing and moisturizing, are only suitable for people without skin allergy, and for people with skin allergy or skin diseases, the skin care products can not be directly used by the people.
The salt proportion of the Wudalianchi volcano cold spring water is basically consistent with the proportion of various ions in human body fluid and blood, the digestion function of human body and the water and salt metabolism of the human body can be effectively regulated, a proper amount of ferrous ions are beneficial to the direct absorption of hematopoietic elements (iron) by the human body, the content of ionized calcium in the product is particularly high (95-110mg/L), the calcium required by the human body can be supplemented by adopting the technical polypeptide molecule permeation, the functions of a biological enzyme system and an endocrine system of the human body can be improved, particularly, the effect on skin diseases and the like is better, and a plurality of diseases of the biological enzyme system of the human body and the like can be improved.
Preferably, the wet whitening and yellow removing composition further comprises 0.1-1% of a preservative by weight percentage, wherein the preservative is p-hydroxyacetophenone.
The invention also provides a preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which comprises the following steps:
1) weighing bioactive polypeptide, glabridin, matrix component, preservative and cold spring water according to the weight ratio;
2) stirring cold spring water and matrix components uniformly, heating to 80-100 deg.C, keeping the temperature for 20-60min, cooling to 40-50 deg.C, adding bioactive polypeptide, glabridin and antiseptic, and stirring to obtain composition with effects of keeping moisture, whitening skin, removing yellow and preventing allergy.
The invention also provides a skin care product which comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 5-80% of the total weight of the skin care product in percentage by weight. More preferably, the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 20-80% of the total weight of the skin care product, and more preferably, the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 40-70% of the total weight of the skin care product.
Preferably, the skin care product comprises toner, lotion, essence, cream, eye cream, facial cleanser, foundation and isolation milk.
The invention combines bioactive polypeptide with trace elements in the cold spring water of the Wudalianchi pool, regulates the peripheral nerve of a human body through the functional trace elements in the cold spring water, combines polypeptide molecules with the trace elements in ionic forms, permeates into epidermal cells, delivers the functional elements to a skin tissue structure through blood microcirculation, activates the cells of the skin tissue structure, regulates the structural frame chain of the tissue structure in the human body, absorbs effective substances such as wrinkle resistance, allergy resistance, inflammation resistance and the like, and achieves the effects of moisturizing, wrinkle resistance, allergy resistance, inflammation resistance and speckle reduction.
The product of the invention develops a skin care product which can be used by people with sensitive skin on the basis of the functions of the common moisturizing skin care product, has good moisturizing, whitening, freckle removing and other effects, also has anti-sensitivity performance, has good repairing effect on broken wrinkles, greatly improves the capability of removing fine wrinkles, and has excellent freckle removing effect and anti-inflammation effect.
The invention has the beneficial effects that: the invention inhibits the formation of melanin from the skin source, and has the effects of moisturizing, whitening, removing yellow, lightening color spots and making the skin tender and fair; cold spring water collected from the volcano of the Wudalianchi is added, the cold spring water is rich in trace elements such as potassium, sodium, calcium, magnesium, iron, manganese, fluorine, chromium, zinc, copper, barium and the like, and the content of the trace elements is equivalent to the proportion required by a human body, so that the digestive function and the water and salt metabolism of the human body can be effectively regulated, the functions of a biological enzyme system and an endocrine system of the human body can be improved, and the cold spring water has good medicinal value and good curative effect on skin diseases; the skin care product is suitable for general people, people with sensitive skin or skin diseases, and can further improve the skin diseases.
Detailed Description
Example 1
The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.002% of bioactive polypeptide,
3 percent of glabridin,
the matrix component is 16 percent,
0.1 percent of preservative (hydroxyacetophenone),
the balance is the volcanic cold spring water of the five great junctures.
The bioactive polypeptide comprises the following components in percentage by weight based on the total weight of the composition: 0.0002% carnosine, 0.0005% palmitoyl tripeptide-1, 0.001% palmitoyl tripeptide-3, 0.0002% palmitoyl tetrapeptide-7, and 0.0001% hexapeptide.
The matrix component consists of the following components in percentage by weight based on the total weight of the composition: 2% of butanediol, 8% of sodium hyaluronate and 6% of glycerol polymethacrylate.
The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following steps:
1) weighing bioactive polypeptide, glabridin, matrix component, preservative and cold spring water according to the weight ratio;
2) stirring cold spring water and matrix components uniformly, heating to 80-100 deg.C, keeping the temperature for 20-60min, cooling to 40-50 deg.C, adding bioactive polypeptide, glabridin and antiseptic, and stirring to obtain composition with effects of keeping moisture, whitening skin, removing yellow and preventing allergy.
Example 2
The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.01 percent of bioactive polypeptide,
glabridin 5 percent,
the matrix component is 20 percent,
0.3 percent of preservative (hydroxyacetophenone),
the balance is the volcanic cold spring water of the five great junctures.
The bioactive polypeptide comprises the following components in percentage by weight based on the total weight of the composition: 0.002% carnosine, 0.004% palmitoyl tripeptide-1, 0.001% palmitoyl tripeptide-3, 0.002% palmitoyl tetrapeptide-7, and 0.001% hexapeptide.
The matrix component consists of the following components in percentage by weight based on the total weight of the composition: 3% of butanediol, 10% of sodium hyaluronate and 7% of glycerol polymethacrylate.
The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is the same as that of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy in example 1.
Example 3
The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.05 percent of bioactive polypeptide,
the glabridin accounts for 6 percent,
25 percent of the matrix component,
0.5 percent of preservative (hydroxyacetophenone),
the balance is the volcanic cold spring water of the five great junctures.
The bioactive polypeptide comprises the following components in percentage by weight based on the total weight of the composition: 0.01% carnosine, 0.01% palmitoyl tripeptide-1, 0.01% palmitoyl tripeptide-3, 0.01% palmitoyl tetrapeptide-7, and 0.01% hexapeptide.
The matrix component consists of the following components in percentage by weight based on the total weight of the composition: 6% of butanediol, 9% of sodium hyaluronate and 10% of glycerol polymethacrylate.
The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is the same as that of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy in example 1.
Example 4
The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.1 percent of bioactive polypeptide,
the glabridin accounts for 7 percent,
32 percent of the matrix component,
0.8 percent of preservative (hydroxyacetophenone),
the balance is the volcanic cold spring water of the five great junctures.
The bioactive polypeptide comprises the following components in percentage by weight based on the total weight of the composition: 0.01% carnosine, 0.02% palmitoyl tripeptide-1, 0.03% palmitoyl tripeptide-3, 0.02% palmitoyl tetrapeptide-7, and 0.02% hexapeptide.
The matrix component consists of the following components in percentage by weight based on the total weight of the composition: 6% of butanediol, 12% of sodium hyaluronate and 14% of glycerol polymethacrylate.
The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is the same as that of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy in example 1.
Example 5
The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy comprises the following components in percentage by weight:
0.8 percent of bioactive polypeptide,
the glabridin accounts for 8 percent,
the matrix component is 38 percent,
1 percent of preservative (hydroxyacetophenone),
the balance is the volcanic cold spring water of the five great junctures.
The bioactive polypeptide comprises the following components in percentage by weight based on the total weight of the composition: 0.1% carnosine, 0.2% palmitoyl tripeptide-1, 0.2% palmitoyl tripeptide-3, 0.1% palmitoyl tetrapeptide-7, and 0.2% hexapeptide.
The matrix component consists of the following components in percentage by weight based on the total weight of the composition: 8% of butanediol, 15% of sodium hyaluronate and 15% of glycerol polymethacrylate.
The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is the same as that of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy in example 1.
Example 6
The toner comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which is prepared in example 3, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 35% of the total weight of the toner in percentage by weight, and the balance is deionized water, isoprene glycol and essence.
The using effect of the toner containing the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is tested.
The test population: 100 female volunteers 28-50 years old, divided into 10 groups of 10 persons each, with normal, dry and sensitive skin; the test method comprises the following steps: after the subjects clean the faces, the skin roughness, wrinkle depth and skin glossiness are observed by a skin surface analyzer and the using effect is observed and recorded by using the toner prepared by the invention respectively for 2 times a day and 1 month. After the skin care product is used, women with sensitive skin have no skin allergy in the using process, and the sensitive skin is greatly improved.
Table 1 skin roughness test results
Rate of reduction of roughness 80% or more 70-80% 60-70% 50-60% 40-50% 30-40% Less than 30
Number of people 42 28 14 8 6 2 0
Ratio of 42% 28% 14% 8% 6% 2% 0%
Table 2 wrinkle test results
Figure BDA0001630723470000061
Figure BDA0001630723470000071
Table 3 skin gloss test results
Figure BDA0001630723470000072
Example 7
An emulsion comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which is prepared in example 3, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 50% of the total weight of the emulsion in percentage by weight, and the balance is deionized water, isopropyl myristate, ceramide 3, xanthan gum, carbomer and the like.
The using effect of the emulsion containing the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is tested.
The test population: 100 female volunteers 28-50 years old, divided into 10 groups of 10 persons each, with normal, dry and sensitive skin; the test method comprises the following steps: after the subjects cleaned their faces, the emulsions prepared according to the present invention were used 2 times a day for 1 month, respectively, and the skin roughness, wrinkle depth, skin gloss were observed with a skin surface analyzer, and the effects of the use were observed and recorded. After the skin care product is used, women with sensitive skin have no skin allergy in the using process, and the sensitive skin is greatly improved.
Table 4 skin roughness test results
Rate of reduction of roughness 80% or more 70-80% 60-70% 50-60% 40-50% 30-40% Less than 30
Number of people 21 42 21 13 2 1 0
Ratio of 21% 42% 21% 13% 2% 1% 0%
Table 5 wrinkle test results
Reduction rate of wrinkles 40% or more 30-40% 20-30% 10-20% Less than 10%
Number of people 13 43 30 13 1
Ratio of 13% 43% 30% 13% 1%
Table 6 skin gloss test results
Figure BDA0001630723470000073
Example 8
An essence comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which is prepared in example 3, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 45% of the total weight of the essence in percentage by weight, and the balance is deionized water, glycerol, caprylyl glycol, ceramide 1, cholesterol and the like.
The using effect of the essence containing the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is tested.
The test population: 100 female volunteers 28-50 years old, divided into 10 groups of 10 persons each, with normal, dry and sensitive skin; the test method comprises the following steps: after the subjects cleaned their faces, the skin roughness, wrinkle depth, skin gloss were observed with a skin surface analyzer 2 times a day for 1 month, and the effects of the use were observed and recorded, respectively, using the essence prepared according to the present invention. After the skin care product is used, women with sensitive skin have no skin allergy in the using process, and the sensitive skin is greatly improved.
Table 7 skin roughness test results
Rate of reduction of roughness 80% or more 70-80% 60-70% 50-60% 40-50% 30-40% Less than 30
Number of people 18 36 23 16 6 1 0
Ratio of 18% 36% 23% 16% 6% 1% 0%
Table 8 wrinkle test results
Reduction rate of wrinkles 40% or more 30-40% 20-30% 10-20% Less than 10%
Number of people 13 43 30 13 1
Ratio of 13% 43% 30% 13% 1%
Table 9 skin gloss test results
Figure BDA0001630723470000081
Example 9
A facial cream comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which is prepared in example 3, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 60% of the total weight of the facial cream, and the balance is deionized water, L-ascorbic acid, 2-glucoside, Babaifang, oat beta-glucan and the like.
The using effect of the cream containing the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is tested.
The test population: 100 female volunteers 28-50 years old, divided into 10 groups of 10 persons each, with normal, dry and sensitive skin; the test method comprises the following steps: after the subjects cleaned their faces, the creams prepared according to the present invention were used 2 times a day for 1 month, respectively, and the skin roughness, wrinkle depth, skin gloss were observed with a skin surface analyzer, and the effects of the use were observed and recorded. After the skin care product is used, women with sensitive skin have no skin allergy in the using process, and the sensitive skin is greatly improved.
TABLE 10 skin roughness test results
Rate of reduction of roughness 80% or more 70-80% 60-70% 50-60% 40-50% 30-40% Less than 30
Number of people 11 52 20 14 2 1 0
Ratio of 11% 52% 20% 14% 2% 1% 0%
Table 11 wrinkle test results
Reduction rate of wrinkles 40% or more 30-40% 20-30% 10-20% Less than 10%
Number of people 13 43 30 13 1
Ratio of 13% 43% 30% 13% 1%
Table 12 skin gloss test results
Figure BDA0001630723470000091
Example 10
An eye cream comprises the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, which is prepared in example 3, wherein the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy accounts for 65% of the total weight of the eye cream in percentage by weight, and the balance is deionized water, porphyridium extract, polyethylene glycol-90M, glycosyl trehalose, willow extract and the like.
The use effect of the eye cream containing the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is tested.
The test population: 100 female volunteers 28-50 years old, divided into 10 groups of 10 persons each, with normal, dry and sensitive skin; the test method comprises the following steps: after the face of a subject is cleaned, the eye cream prepared by the invention is respectively used for smearing the eye part for 2 times per day for 1 month, the roughness, the wrinkle depth and the skin glossiness of the eye part skin are observed by a skin surface analyzer, and the using effect is observed and recorded. After the eye-skin allergy-free facial mask is used, women with sensitive skin do not have the situation of eye skin allergy in the using process. Table 13 skin roughness test results
Rate of reduction of roughness 80% or more 70-80% 60-70% 50-60% 40-50% 30-40% Less than 30
Number of people 23 46 18 11 1 1 0
Ratio of 23% 46% 18% 11% 1% 1% 0%
Table 14 wrinkle test results
Figure BDA0001630723470000092
Figure BDA0001630723470000101
Table 15 skin gloss test results
Figure BDA0001630723470000102
The above analysis shows that the moisturizing, whitening and yellow-removing composition prepared by the invention has excellent moisturizing, anti-wrinkle, anti-allergy, anti-inflammation and speckle-lightening effects, and can be added into skin care products such as toner, emulsion, essence, cream, eye cream, barrier emulsion and the like.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and they are included in the scope of the present invention.

Claims (5)

1. The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy is characterized by comprising the following components in percentage by weight:
0.002-1.0% of bioactive polypeptide,
3 to 10 percent of glabridin,
16 to 38 percent of matrix component,
0.1 to 1 percent of preservative,
the balance of cold spring water;
the bioactive polypeptide comprises the following components in percentage by weight: 0.0002-0.2% carnosine, 0.0005-0.2% palmitoyl tripeptide-1, 0.001-0.2% palmitoyl tripeptide-3, 0.0002-0.2% palmitoyl tetrapeptide-7, and 0.0001-0.2% hexapeptide;
the matrix component comprises the following components in percentage by weight based on the total weight of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy: 2-8% of butanediol, 8-15% of sodium hyaluronate and 6-15% of glycerol polymethacrylate;
the cold spring water is volcano cold spring water of Wudalianchi, the pH value is 6.5-7.5, and the contents of trace elements are as follows: 75-90mg/L of potassium, 0.1-0.5mg/L of iron, 60-75mg/L of sodium, 0.06-0.07 mg/L of cobalt, 75-90mg/L of magnesium, 0.01-0.016mg/L of iodine, 95-110mg/L of calcium, 0.001-0.002mg/L of selenium, 0.06-0.08mg/L of zinc, 65-75mg/L of metasilicic acid, 0.02-0.05mg/L of lithium, 1300 mg/L of carbon dioxide and 1600mg/L of sodium and 1.01-1.30mg/L of strontium.
2. The composition with the effects of moisturizing, whitening, removing yellow and preventing allergy according to claim 1, wherein the preservative is p-hydroxyacetophenone.
3. The preparation method of the composition with the effects of moisturizing, whitening, removing yellow and preventing allergy, according to claim 1 or 2, is characterized by comprising the following steps:
1) weighing bioactive polypeptide, glabridin, matrix component, preservative and cold spring water according to the weight ratio;
2) stirring cold spring water and matrix components uniformly, heating to 80-100 deg.C, keeping the temperature for 20-60min, cooling to 40-50 deg.C, adding bioactive polypeptide, glabridin and antiseptic, and stirring to obtain composition with effects of keeping moisture, whitening skin, removing yellow and preventing allergy.
4. A skin care product is characterized by comprising the composition with the effects of moisturizing, whitening, yellowing and preventing allergy according to claim 1 or 2, wherein the composition with the effects of moisturizing, whitening, yellowing and preventing allergy accounts for 5-80% of the total weight of the skin care product in percentage by weight.
5. The skin care product of claim 4, wherein the skin care product comprises a toner, an emulsion, a serum, a cream, an eye cream, a facial cleanser, a foundation, and a barrier cream.
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