CN111265431A

CN111265431A - Moisturizing and repairing composition

Info

Publication number: CN111265431A
Application number: CN202010116651.2A
Authority: CN
Inventors: 樊君
Original assignee: Hefei Junzitang Biotechnology Co Ltd
Current assignee: Hefei Junzitang Biotechnology Co Ltd
Priority date: 2020-02-25
Filing date: 2020-02-25
Publication date: 2020-06-12

Abstract

The invention relates to the technical field of skin care products, and particularly relates to a moisturizing and repairing composition. Comprises 3-9 parts of prinsepia utilis royle oil and 1-5 parts of saccharide isomerate by weight. Also provides a moisturizing repair skin care product, which comprises the moisturizing repair composition; the preparation raw materials comprise 5-15 parts of phase A, 4-10 parts of phase B, 6-15 parts of phase C and water for complementing 100 parts; the phase A comprises a first humectant, a thickening agent, a first emollient, a first emulsifier and an antioxidant; the phase B comprises a second emollient, a pH regulator, water, a second humectant and a second emulsifier; the phase C comprises bacteriostatic agent, third humectant, antiinflammatory agent, and water.

Description

Moisturizing and repairing composition

Technical Field

The invention relates to the technical field of skin care products, and particularly relates to a moisturizing and repairing composition.

Background

Moisturizing is the most basic step in the beauty treatment process, skin with sufficient moisture naturally transmits the perfect texture of luster, moisture, elasticity and transparency from inside to outside, on the contrary, when the skin lacks water, the skin immunity is reduced, the stimulation degree is enhanced, various stimulation phenomena such as skin dryness and itching can be caused, more seriously, skin cell atrophy, color spot deposition and skin keratinization are caused, the deterioration of skin texture is caused, the appearance defect is brought to people, and the psychological crisis is further caused.

However, the use of skin care products is not limited to the fields of moisturizing and skin care at present, and also extends to the field of adjuvant therapy of certain skin diseases. Such as: skin diseases such as sensitive skin, cosmetic dermatitis, hormone-dependent dermatitis, acne, chloasma, atopic dermatitis and the like are mostly treated by externally applying glucocorticoid or immunomodulator in the prior art, but the drugs have certain side effects, for example, the skin problems such as skin atrophy, pigmentation and the like can be caused by using the glucocorticoid for a long time. Also, there are cases where the skin barrier is impaired due to these skin diseases.

Therefore, the research of developing a skin care product having not only a moisturizing function but also a damaged skin repairing function has been the focus of the research of those skilled in the art.

Disclosure of Invention

In order to solve the technical problems, the invention provides a moisturizing repair composition in a first aspect, which comprises, by weight, 3-9 parts of prinsepia utilis royle oil and 1-5 parts of saccharide isomers.

In a second aspect, the present invention provides a moisturizing repair skin care product prepared from a moisturizing repair composition as described above.

As a preferable technical scheme of the invention, the preparation raw materials of the moisturizing and repairing skin care product comprise, by weight, 5-15 parts of phase A, 4-10 parts of phase B, 6-15 parts of phase C and 100 parts of water.

As a preferred technical solution of the present invention, the phase a includes a first humectant, a thickener, a first emollient, a first emulsifier and an antioxidant, wherein the mass ratio of the first humectant, the thickener, the first emollient, the first emulsifier and the antioxidant is (2-8): (0.2-0.6): (0.1-0.5): (2-6): (0.1-0.4).

As a preferred technical scheme, the first emollient is selected from one or more of dioctyl carbonate, isooctyl palmitate, cetyl ethyl hexanoate and allantoin.

As a preferable technical scheme of the present invention, the phase B includes a second emollient, a PH adjuster, water, a second humectant, and a second emulsifier, wherein the mass ratio of the second emollient, the PH adjuster, the water, the second humectant, and the second emulsifier is (0.5-2): (0.03-1.3): (0.5-1.5): (2-9): (0.3-1.5).

In a preferred embodiment of the present invention, the second emollient is one or more selected from polydimethylsiloxane, cyclopentadimethylsiloxane, polysiloxane-11, and cyclopentadimethylsiloxane.

As a preferred technical scheme of the present invention, the phase C includes a bacteriostatic agent, a third moisturizing agent, an anti-inflammatory agent, and water, wherein the mass ratio of the bacteriostatic agent to the third moisturizing agent to the anti-inflammatory agent to the water is (0.01-0.2): (1-10): (0.5-4): (0.5-1.5).

As a preferable technical solution of the present invention, the third humectant is one or more selected from hexanediol, butanediol, oat glucan, Ximin, sodium pyrrolidone carboxylate, and saccharide isomer.

The third aspect of the invention provides a preparation method of the moisturizing and repairing skin care product, which comprises the following steps:

(1) dissolving phase A in water, heating to 70-90 deg.C, maintaining the temperature for 5-15min, homogenizing for 1-5min, and cooling;

(2) cooling to 50-70 deg.C, adding phase B, homogenizing for 1-4min, and cooling;

(3) cooling to 40-50 deg.C, adding phase C, stirring, cooling to 30-45 deg.C, and discharging.

Has the advantages that: the invention provides a moisturizing and repairing composition, which is prepared by adopting a supercritical carbon dioxide extraction method to obtain prinsepia utilis royle oil, and the prinsepia utilis royle oil and saccharide isomerous body are compounded for use, so that the composition not only has the capability of repairing skin surface cells, but also can improve the capability of shrinking and moisturizing skin; in addition, the composition provided by the invention can be prepared into a moisturizing and repairing skin care product, has excellent storage stability, can play a role in moisturizing, relieving, resisting allergy and repairing, can repair damaged epidermis, enhances the barrier function of stratum corneum and improves the dry and water-deficient state of skin.

Detailed Description

The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.

The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.

When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.

The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.

Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.

In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.

In a preferred embodiment, the moisturizing and repairing composition comprises 4-7 parts by weight of prinsepia utilis royle oil and 1.5-3.5 parts by weight of saccharide isomer.

In a most preferred embodiment, the moisturizing repair composition comprises 5 parts by weight of prinsepia utilis royle oil and 2 parts by weight of saccharide isomer.

Prinsepia utilis Royle oil

The prinsepia utilis royle oil is extracted from prinsepia utilis royle according to a supercritical carbon dioxide extraction method. Prinsepia utilis Royle oil is a good high-grade natural nutritional vegetable oil, has important auxiliary effects on treating hyperlipidemia, reducing cholesterol, and preventing cardiovascular diseases after long-term administration, and can prolong life.

In a preferred embodiment, the extraction method of the prinsepia utilis royle oil comprises the following steps:

(1) removing pulp of Prinsepia utilis Royle to obtain kernel, cleaning, air drying surface water, pulverizing Prinsepia utilis Royle kernel, and sieving with 30 mesh sieve to obtain Prinsepia utilis Royle powder;

(2) placing Prinsepia utilis Royle powder in an extraction kettle, heating the extraction kettle and a separation kettle, and cooling a storage tank. When the temperature reaches the set temperature, the high-pressure pump is opened to pressurize the extraction kettle and the separation kettle, the extraction temperature is 40-60 ℃, the extraction pressure is 25-40MPa, the temperature of the separation kettle is 35-45 ℃, and the pressure is 3-6 MPa. When the pressure reaches the selected extraction pressure and separation pressure, the circulation extraction is started, and CO is regulated₂Dynamic flow, and extracting for 1.5-3h after the system is stable to obtain Prinsepia utilis Royle oil.

In a more preferred embodiment, the extraction method of the prinsepia utilis royle oil comprises the following steps:

(2) placing Prinsepia utilis Royle powder in an extraction kettle, heating the extraction kettle and a separation kettle, and cooling a storage tank. And when the temperature reaches the set temperature, opening the high-pressure pump to pressurize the extraction kettle and the separation kettle, wherein the extraction temperature is 55 ℃, the extraction pressure is 35MPa, the separation kettle temperature is 40 ℃, and the pressure is 4 MPa. When the pressure reaches the selected extraction pressure and separation pressure, the circulation extraction is started, and CO is regulated₂Dynamic flow, and extracting for 2h after the system is stable to obtain the prinsepia utilis royle oil.

At present, for the extraction of prinsepia utilis royle oil, the prior art usually adopts a squeezing method for extraction, but the method has low oil yield and a complicated preparation method, and also comprises the steps of steaming and frying in the oil extraction process, the temperature is higher in the period, the active ingredients in the prinsepia utilis royle are easy to inactivate and deteriorate, and the utilization rate is lower. In order to solve the technical problems, the supercritical carbon dioxide extraction method is adopted for extraction, the extraction temperature is controlled to be 40-60 ℃, on one hand, bioactive substances in the oil material can be effectively preserved, on the other hand, the oil yield can be improved, the content of saturated fatty acid, single unsaturated fatty acid and a plurality of unsaturated fatty acids of the Prinsepia utilis royle oil in the Prinsepia utilis royle oil is balanced, and the stability of the Prinsepia utilis royle oil in the transportation and storage processes is further improved.

Saccharide isomerate

The saccharide isomerate of the invention is colorless or yellowish transparent liquid, is extracted from natural humectant of the cane sugar complex, and can assist water to combine with keratin in the horny layer to achieve the moisturizing effect. The D-glucan is a good water-retaining agent and a good emollient, has the functions of repairing epidermal cells and improving the skin moisturizing capability, is prepared by a biochemical technology, has a composition structure similar to the human cuticle, can be combined with epsilon-amino acid functional groups when being used on the skin, is firmly combined like a magnet, and can maintain the water magnetic field capability of the skin for a long time.

In a preferred embodiment, the saccharide isomers of the present invention are commercially available from manufacturers including, but not limited to, Dismann, Netherlands.

The inventor finds in experiments that the combination of the prinsepia utilis royle oil and the saccharide isomer can play a role in moisturizing and repairing and preventing dry and aging of skin, and the combination of the prinsepia utilis royle oil and the saccharide isomer has a better moisturizing and repairing effect than that of either one of the prinsepia utilis royle oil and the saccharide isomer. The possible reason is that the Prinsepia utilis royle oil obtained by the method is more reasonable in nutritional structure by adopting the supercritical carbon dioxide extraction method for extraction, the proportion of 3 fatty acids of the Prinsepia utilis royle oil is closer to the proportion of fatty acids of a human body, the fat solubility is better, the Prinsepia utilis royle oil not only can be quickly absorbed by the skin of the human body, but also can keep the moisture, nutrition and elasticity of the skin, obviously improves the moisture retention of the skin, improves the degeneration of the horny layer of the skin and repairs the rough. The skin moisturizing cream is rich in monounsaturated fatty acid, has certain oxidation resistance, and can prevent skin aging and realize the effect of skin regeneration and repair while increasing the skin moisturizing effect. The saccharide isomer contains D-glucan, which can be combined with epsilon-amino acid functional group when used on skin to assist water to combine with keratin in cuticle, and can maintain the water magnetic field capability of skin for a long time. The composition has a synergistic effect with prinsepia utilis royle oil, can enhance the repair of epidermal cells of the composition, can improve the skin moisturizing capability, promotes the synthesis of hyaluronic acid, increases the expression level of acid sphingomyelin enzyme-based bacteria, and enables the skin to be smooth and tender. However, the stability of the prinsepia utilis royle oil is poor, and the inventors surprisingly found that the technical problems can be effectively solved by adding the saccharide isomerate, and the inventors speculate that the polar groups distributed on the molecular chain of the saccharide isomerate interact to form various intramolecular hydrogen bonds, so that partial unsaturated fatty acid can be wrapped, the interference of oxygen is further prevented, and the stability of the prinsepia utilis royle oil is improved. In particular, the mass ratio of the prinsepia utilis royle oil to the saccharide isomerate is (3-9): the best effect was obtained in the case of (1-5).

In a preferred embodiment, the preparation raw materials of the moisturizing repair skin care product comprise, by weight, 5-15 parts of phase A, 4-10 parts of phase B, 6-15 parts of phase C and the balance of water to 100 parts.

Phase A

In a preferred embodiment, the phase a of the present invention comprises a first humectant, a thickener, a first emollient, a first emulsifier, and an antioxidant, wherein the mass ratio of the first humectant, the thickener, the first emollient, the first emulsifier, and the antioxidant is (2-8): (0.2-0.6): (0.1-0.5): (2-6): (0.1-0.4).

In a more preferred embodiment, the phase a of the present invention comprises a first humectant, a thickener, a first emollient, a first emulsifier, and an antioxidant, wherein the mass ratio of the first humectant, the thickener, the first emollient, the first emulsifier, and the antioxidant is (3-7): (0.3-0.5): (0.2-0.4): (3-5): (0.2-0.3).

In a most preferred embodiment, the phase a of the present invention comprises a first humectant, a thickener, a first emollient, a first emulsifier, and an antioxidant, wherein the mass ratio of the first humectant, the thickener, the first emollient, the first emulsifier, and the antioxidant is 5: 0.4: 0.3: 4: 0.25.

a first humectant

The first moisturizing agent is a cosmetic raw material with the functions of moisturizing and repairing a sebum membrane, and the raw material has a special molecular structure, can adsorb and retain moisture, and maintains the skin barrier function while maintaining the skin hydration.

In a preferred embodiment, the first humectant of the present invention is one or more of glycerin, pentanediol, and dipropylene glycol.

In a most preferred embodiment, the first humectant of the present invention is glycerin.

Thickening agent

The thickening agent can improve the viscosity of a system and keep the system in a uniform and stable stroking state or an opacified state.

In a preferred embodiment, the thickener according to the invention is selected from one or more of hydroxyethylcellulose, hydroxypropylcellulose, carbomer, xanthan gum, guar gum, carrageenan.

In a most preferred embodiment, the thickener of the present invention is a carbomer.

First emollient

The first emollient of the present invention is a cosmetic ingredient that helps to maintain the soft, pliable, smooth appearance of skin. The function of emollients is to remain on the skin surface and to provide lubrication within the stratum corneum. Generally, the skin fills the spaces in the skin surface, replacing the lipid lost in the stratum corneum, reducing the scaly skin, and improving the appearance of the skin.

In a preferred embodiment, the first emollient of the present invention is selected from one or more of the group consisting of dioctyl carbonate, isooctyl palmitate, cetyl ethylhexanoate, allantoin.

In a most preferred embodiment, the first emollient of the present invention is allantoin.

The allantoin has good skin moistening effect, can restore the smoothness and the luster of chapped and rough skin, can enhance the water absorption capacity of the outermost layer of the skin and hair, improves the hydrophilic capacity of keratin molecules, restores the damaged cuticle and restores the natural water absorption capacity of the cuticle. The allantoin can promote the water absorption capacity of the outermost layer of the skin, reduce the water evaporation of the skin, and form a lubricating film on the surface of the skin to seal the water, thereby achieving the effect of moisturizing the skin. Allantoin has unique keratolytic properties, and therefore has the effect of softening keratin, and it removes the keratin, which is a metabolic waste, and fills the interstitial spaces with water to make the skin moist and shiny. The allantoin is an amphoteric compound, can be combined with multiple substances to form a double salt, and has the effects of protecting from light, sterilizing, preventing corrosion, relieving pain, and resisting oxidation.

First emulsifier

The first emulsifier of the present invention is a compound capable of forming a stable emulsion from a mixture of two or more immiscible components. The principle of action is that during the emulsification process, the dispersed phase is dispersed in the form of droplets (micron-sized) in the continuous phase, and the emulsifier reduces the interfacial tension of the components in the mixed system and forms a firmer film on the surface of the droplets or forms an electric double layer on the surface of the droplets due to the electric charge given by the emulsifier, thus preventing the droplets from aggregating with each other and maintaining a uniform emulsion.

In a preferred embodiment, the first emulsifier of the present invention is a nonionic surfactant.

In a more preferred embodiment, the nonionic surfactants of the present invention are commercially available from a manufacturer including, but not limited to, M68 from Diehigh (China) chemical Co., Ltd, LC available from Hallstar, Italy.

In a preferred embodiment, the nonionic surfactant of the present invention is M68 and LC, wherein the mass ratio of M68 to LC is (1-2): 1.

in a most preferred embodiment, the nonionic surfactant of the present invention is M68 and LC, wherein the mass ratio of M68 to LC is 1.7: 1.

the invention adopts the emulsifier to improve the dispersion effect of the prinsepia utilis royle oil in the system, thereby improving the moisturizing and repairing capabilities of the skin care product, but experiments find that the prepared moisturizing and repairing skin care product is easy to re-precipitate in the using or storing process, and the moisturizing and repairing performance of the prepared skin care product is poorer, and when the sodium acrylate/sodium acryloyldimethyl taurate copolymer (and) isocetyl alkane (and) polysorbate-80 are added in the system, the problems can be effectively improved, and the possible reason is that the nonionic glycosyl emulsifier is compounded with the acid ester type-alcohol ester type surfactant, can be adsorbed on the surface of the prinsepia utilis royle oil, can effectively reduce the surface free energy of the prinsepia utilis royle oil, form a firm emulsion film, thereby reducing the oil-water interfacial tension and effectively preventing the aggregation of liquid drops, however, the emulsification effect is deteriorated after a long time of standing, and it is likely that the surface tension of the oil is affected because the emulsifier is easily migrated during the standing. The sodium acrylate/sodium acryloyldimethyl taurate copolymer (and) isohexadecane (and) polysorbate-80 is a high molecular surfactant, has excellent film-separating property, can form a large network structure, and increases the dispersion stability of the prinsepia utilis royle oil in a water system.

Antioxidant agent

The antioxidant of the present invention is a substance that prevents adverse effects of oxygen. It is a class of substances that helps to trap and neutralize free radicals, thereby removing the damage that free radicals cause to the human body.

In a preferred embodiment, the antioxidant according to the invention is selected from one or more of vitamin C, vitamin E, vitamin a and derivatives thereof, ergothioneine, curcumin, tetrahydrocurcumin, tocopheryl acetate.

In a most preferred embodiment, the antioxidant of the present invention is tocopheryl acetate.

Phase B

In a preferred embodiment, the phase B of the present invention comprises a second emollient, a PH adjuster, water, a second humectant, and a second emulsifier, wherein the mass ratio of the second thickener, the PH adjuster, the water, the second humectant, and the second emulsifier is (0.5-2): (0.03-1.3): (0.5-1.5): (2-9): (0.3-1.5).

In a more preferred embodiment, phase B of the present invention comprises a second emollient, a PH adjuster, water, a second humectant, and a second emulsifier, wherein the mass ratio of the second emollient, the PH adjuster, the water, the second humectant, and the second emulsifier is (0.8-1.2): (0.05-1): (0.8-1.2): (3-7): (0.5-1).

In a most preferred embodiment, phase B of the present invention comprises a second emollient, a PH adjuster, water, a second humectant, and a second emulsifier, wherein the mass ratio of the second emollient, the PH adjuster, the water, the second humectant, and the second emulsifier is 1: 0.08: 1: 5: 0.8.

second emollient

In a preferred embodiment, the second emollient of the present invention is selected from one or more of the group consisting of dimethicone, cyclopentadecyldimethicone, polysiloxane-11, and cyclopentadecyldimethicone.

In a most preferred embodiment, the second emollient of the present invention is polydimethylsiloxane, which is commercially available from a manufacturer including, but not limited to, dow corning under the designation DC 345.

PH regulator

In a preferred embodiment, the PH adjusting agent of the present invention is selected from one or more of sodium carbonate, sodium bicarbonate, and sodium hydroxide.

In a most preferred embodiment, the pH adjusting agent of the present invention is sodium hydroxide.

Second humectant

In a preferred embodiment, the second humectant of the present invention is prinsepia utilis royle oil.

Second emulsifier

In a preferred embodiment, the second emulsifier of the present invention is commercially available from a manufacturer including, but not limited to, Saybolt, under the trademark EG.

Phase C

In a preferred embodiment, the phase C of the present invention includes a bacteriostatic agent, a third moisturizing agent, an anti-inflammatory agent, and water, wherein the mass ratio of the bacteriostatic agent to the third moisturizing agent to the anti-inflammatory agent to the water is (0.01-0.2): (1-10): (0.5-4): (0.5-1.5).

In a more preferred embodiment, phase C of the present invention includes a bacteriostatic agent, a third moisturizing agent, an anti-inflammatory agent, and water, wherein the mass ratio of the bacteriostatic agent to the third moisturizing agent to the anti-inflammatory agent to the water is (0.05-0.15): (3-8): (1.5-3): (0.8-1.2).

In a most preferred embodiment, the phase C of the present invention includes a bacteriostatic agent, a third moisturizing agent, an anti-inflammatory agent, and water, wherein the mass ratio of the bacteriostatic agent to the third moisturizing agent to the anti-inflammatory agent to the water is 0.1: 6.9: 2.1: 1.

bacteriostatic agent

The bacteriostatic agent is a substance capable of inhibiting the growth of bacteria. The bacteriostatic agent may not kill bacteria, but it can inhibit the growth of bacteria, prevent the bacteria from breeding too much and endanger health.

In a preferred embodiment, the bacteriostatic agent of the present invention is selected from one or more of luteolin, arbutin, astragalin and caprylyl hydroximic acid.

In a most preferred embodiment, the bacteriostatic agent of the present invention is caprylhydroxamic acid.

Third moisturizing agent

In a preferred embodiment, the third humectant of the present invention is selected from one or more of hexylene glycol, butylene glycol, oat glucan, Ximin, sodium pyrrolidone carboxylate, saccharide isomerate.

In a preferred embodiment, the third humectant of the present invention is selected from hexylene glycol, butylene glycol, oat glucan, sodium oxypyrrolidone, a sugar isomer, wherein the mass ratio of hexylene glycol, butylene glycol, oat glucan, sodium oxyphenzyl, sodium pyrrolidonecarboxylate, sugar isomer is (0.1-1): (0.2-1): (1-6): (0.1-1): (0.1-1): (1-5).

In a more preferred embodiment, the third humectant of the present invention is selected from hexylene glycol, butylene glycol, oat glucan, sodium oxypyrrolidone, a sugar isomer, wherein the mass ratio of hexylene glycol, butylene glycol, oat glucan, sodium oxypyrrolidone carboxylate, sugar isomer is (0.3-0.7): (0.3-0.6): (2-5): (0.3-0.7): (0.3-0.7): (1-4).

In a most preferred embodiment, the third humectant of the present invention is selected from hexylene glycol, butylene glycol, oat glucan, sodium oxypyrrolidone, a sugar isomer, wherein the mass ratio of hexylene glycol, butylene glycol, oat glucan, sodium oxypyrrolidone carboxylate, sugar isomer is 0.5: 0.4: 3: 0.5: 0.5: 2.

in a preferred embodiment, the sodium pyrrolidone carboxylate of the present invention is commercially available from a source including, but not limited to, Korea International trade, Inc. under the designation NL-50.

The inventor finds that oat glucan and saccharide isomerate are used as a humectant and have a certain synergistic effect, so that the oat glucan can effectively help skin to keep moisture and prevent the moisture from losing through the epidermis, is a better skin protection immune promoter, can promote the proliferation of skin cells and the synthesis of collagen and elastin, strengthen cell metabolism, delay skin aging and efficiently repair the skin, and on the other hand, the oat glucan mainly comprises β -glucan, wherein a molecular chain contains a large amount of active groups, and the active groups are compounded with the saccharide isomerate to form a large amount of intra-molecular and intermolecular hydrogen bonds, so that the contact of unsaturated fatty acid in the prinsepia utilis royle oil and oxygen is effectively prevented, and the stability of the prinsepia royle oil in the skin is further improved.

In addition, the moisturizer also comprises Xiyan and sodium pyrrolidone carboxylate, the Xiyan belongs to a skin conditioner, is an acidic mucopolysaccharide, can absorb 1000 times of moisture of the body weight of the Xiyan, so as to achieve the purposes of keeping the moisture of the skin, preventing the moisture from losing through the epidermis and repairing the barrier when the skin is damaged, so that the skin does not feel dry and glossy after being used, the Xiyan moisturizer can improve the skin nutrition metabolism, make the skin soft and smooth, remove wrinkles, increase the elasticity and prevent aging, and is a good transdermal absorption promoter while keeping moisture. The compound can be used together with sodium pyrrolidone carboxylate which is a natural component of skin, has the function of strengthening cutin, is used for enhancing the self moisturizing capability of the skin, and can play a more ideal effect of promoting nutrient absorption.

Anti-inflammatory agents

In a preferred embodiment, the anti-inflammatory agent of the present invention is a combination of the glycyrrhizic acid xylem and the gentiana macrophylla extract, wherein the mass ratio of the glycyrrhizic acid xylem to the gentiana macrophylla extract is (0.15-0.15): (1-3).

In a most preferred embodiment, the anti-inflammatory agent of the present invention is a combination of dimethyl glycyrrhizinate and an extract of gentiana macrophylla, wherein the mass ratio of the dimethyl glycyrrhizinate to the extract of gentiana macrophylla is 0.1: 2.

the third aspect of the invention provides a preparation method of a moisturizing and repairing skin care product, which comprises the following steps:

In a most preferred embodiment, the method for preparing the moisturizing and repairing skin care product comprises the following steps:

(1) dissolving A phase in water, heating to 85 deg.C, maintaining the temperature for 10min, homogenizing for 3min, and cooling;

(2) cooling to 60 deg.C, adding phase B, homogenizing for 2min, and cooling;

(3) cooling to 45 deg.C, adding phase C, stirring, cooling to 40 deg.C, and discharging.

It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.

In addition, the raw materials used are commercially available from national chemical reagents, unless otherwise specified.

Examples

In order to better understand the above technical solutions, the following detailed descriptions will be provided with reference to specific embodiments. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention. In addition, the raw materials are commercially available and the extraction methods of the extract are all conventional extraction methods, if not otherwise specified.

Example 1

Provides a moisturizing and repairing skin care product, which comprises the following raw materials of, by weight, 9.95 parts of phase A, 7.88 parts of phase B, 10.1 parts of phase C and 100 parts of water.

The phase A comprises a first humectant, a thickening agent, a first emollient, a first emulsifier and an antioxidant, wherein the mass ratio of the first humectant, the thickening agent, the first emollient, the first emulsifier and the antioxidant is 5: 0.4: 0.3: 4: 0.25.

the first humectant is glycerin.

The thickening agent is carbomer.

The first emollient is allantoin.

The first emulsifier is a nonionic surfactant.

The nonionic surfactant is commercially available from M68 of dielgar (china) chemical limited, LC available from Hallstar corporation, italy, wherein the mass ratio of M68 to LC is 1.7: 1.

the antioxidant is tocopherol acetate.

And the phase B comprises a second emollient, a pH regulator, water, a second humectant and a second emulsifier, wherein the mass ratio of the second emollient to the pH regulator to the water to the second humectant to the second emulsifier is 1: 0.08: 1: 5: 0.8.

the second emollient is polydimethylsiloxane, commercially available from Dow Corning, and is available under the designation DC 345.

The pH regulator is sodium hydroxide.

The second humectant is prinsepia utilis royle oil.

The second emulsifier is commercially available from a manufacturer as Saibox under the brand EG.

The phase C comprises a bacteriostatic agent, a third humectant, an anti-inflammatory agent and water, wherein the mass ratio of the bacteriostatic agent to the third humectant to the anti-inflammatory agent to the water is 0.1: 6.9: 2.1: 1.

the bacteriostatic agent is caprylyl hydroximic acid.

The third humectant is selected from glycol, butanediol, oat glucan, Ximin, sodium pyrrolidone carboxylate and saccharide isomerate, wherein the mass ratio of the glycol, the butanediol, the oat glucan, the Ximin, the sodium pyrrolidone carboxylate and the saccharide isomerate is 0.5: 0.4: 3: 0.5: 0.5: 2.

the sodium pyrrolidone carboxylate is commercially available from Korea International trade Shanghai Co., Ltd under the trade designation NL-50.

The anti-inflammatory agent is a combination of the dimethyl glycyrrhizinate and the gentiana macrophylla extract, wherein the mass ratio of the dimethyl glycyrrhizinate to the gentiana macrophylla extract is 0.1: 2.

the preparation method of the moisturizing and repairing skin care product comprises the following steps:

(2) cooling to 60 deg.C, adding phase B, homogenizing for 2min, and cooling;

Example 2

Provides a moisturizing and repairing skin care product, which comprises the following raw materials of 5 parts of phase A, 4 parts of phase B, 6 parts of phase C and 100 parts of water in parts by weight.

the first humectant is glycerin.

The thickening agent is carbomer.

The first emollient is allantoin.

The first emulsifier is a nonionic surfactant.

the antioxidant is tocopherol acetate.

The pH regulator is sodium hydroxide.

The second humectant is prinsepia utilis royle oil.

the bacteriostatic agent is caprylyl hydroximic acid.

(2) cooling to 60 deg.C, adding phase B, homogenizing for 2min, and cooling;

Example 3

The moisturizing and repairing skin care product is prepared from 15 parts by weight of phase A, 10 parts by weight of phase B, 15 parts by weight of phase C and 100 parts by weight of water.

the first humectant is glycerin.

The thickening agent is carbomer.

The first emollient is allantoin.

The first emulsifier is a nonionic surfactant.

the antioxidant is tocopherol acetate.

The pH regulator is sodium hydroxide.

The second humectant is prinsepia utilis royle oil.

the bacteriostatic agent is caprylyl hydroximic acid.

(2) cooling to 60 deg.C, adding phase B, homogenizing for 2min, and cooling;

Example 4

Similar to example 1, except that the second humectant was absent from phase B.

Example 5

Similar to example 1, except that the second emulsifier in phase B was polyoxyethylene laurate, commercially available from Haian petrochemical company, Inc. under the LAE-4 designation.

Example 6

Similar to example 1, except that no second emulsifier was present in phase B.

Example 7

Similar to example 1, except that the third humectant in phase C was free of oat glucan.

Example 8

Similar to example 1, except that the third humectant in phase C contains no sugar isotopolymer isomers.

Example 9

Similar to example 1, except that the mass ratio of oat glucan to saccharide isomer in the third humectant was 1: 5.

example 10

Similar to example 1, except that the mass ratio of oat glucan to saccharide isomer in the third humectant was 6: 1.

evaluation of Performance

1. And (3) stability testing: the moisturizing repair compositions prepared in examples 1 to 10 were subjected to the following tests, and the test results are shown in table 1 below;

sensory testing: visually observing the properties of the product to see whether the product is abnormal or not;

heat resistance test: putting the sample into an electric heating constant temperature incubator at the temperature of (40 +/-1) DEG C for 24 hours, and observing whether phenomena such as thinning, discoloration, layering, hardness change and the like exist after the temperature is recovered to judge the heat resistance of the sample;

cold resistance test: putting the sample into a refrigerator at the temperature of-5 ℃ for 24 hours, and observing whether phenomena such as thinning, color change, layering, hardness change and the like exist after the room temperature is recovered so as to judge the cold resistance of the sample;

and (3) centrifugal test: and (3) placing the sample in a centrifuge, testing for 30min at the rotating speed of 3000r/min, and observing the separation and delamination conditions of the sample.

TABLE 1 stability test results

2. Test of moisturizing Effect

Experimental products: the moisturizing repair skin care products prepared in examples 1, 4, 7-10.

Number of test population: 60 people, female; age: between 25-60 years of age, divided into 6 groups of 10 people each.

Testing an instrument: a skin moisture tester Corneometer CM 825 is used for detecting the moisture content of the stratum corneum of the skin;

test area: the inner side of the forearm of the right hand;

the test method comprises the following steps: the test sample is (2.0 +/-0.1) mg/cm²The amount of (a) was applied in a single pass, using a latex finger cuff to apply the sample to a 3cm x 3cm test area;

and (3) testing period: 0h, 2h, 4h and 6 h;

scheme design: 0 h: no product is used 2-3 days before the tested part, and water can not be contacted for 1-3 h. Before the test, the inner side of the forearm is cleaned uniformly and wiped clean. Prior to testing, subjects sit still in a laboratory at a temperature of 21. + -. 1 ℃ and a relative humidity of 50. + -. 10% for 20min, without drinking water or drink, with the forearms exposed. After the test is started, the parameter measurement of the moisture content of the stratum corneum of the skin is carried out on the sample smearing area.

2 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.

4 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.

6 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.

The moisture content of the inner horny layer of the left and right forearms was measured in 10 subjects of each group, and the average of the moisture content of the inner right arm of the 10 subjects was obtained from the data, and the results are shown in table 2.

TABLE 2 Performance test results

3. Skin barrier repair test

The experimental method comprises the following steps: 60 volunteer subjects with different hormonal dermatitis degrees in 20-50 years old are selected for application test, the skin care product prepared by the method is continuously used for 4 months, the repair efficacy performance project is subjected to sensory evaluation, and 60 subjects are randomly divided into 6 groups. The statistical results are shown in table 3 below:

the criteria for determination are as follows:

the effect is shown: after the skin is inspected, the redness and itching symptoms are completely disappeared, the skin becomes smooth, and no inflammation exists;

the method has the following advantages: the symptoms are obviously relieved after the medicine is used;

and (4) invalidation: after use, the symptoms are not reduced or are aggravated.

TABLE 3 data results

	Show effect	Is effective	Invalidation
				Example 1	8	2	0
Example 2	3	3	4
				Example 3	4	4	2
Example 4	3	4	3
				Example 5	6	2	2
Example 6	6	3	1

The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims

1. The moisturizing and repairing composition is characterized by comprising, by weight, 3-9 parts of prinsepia utilis royle oil and 1-5 parts of saccharide isomerate.

2. A moisturizing repair skin care product characterized in that it is prepared from a raw material comprising the moisturizing repair composition according to claim 1.

3. The moisturizing repairing skin care product according to claim 2, characterized in that the preparation raw materials comprise, by weight, 5-15 parts of phase A, 4-10 parts of phase B, 6-15 parts of phase C and water for making up 100 parts.

4. The moisturizing repair skin care product according to claim 3, wherein the phase A comprises a first humectant, a thickener, a first emollient, a first emulsifier and an antioxidant, wherein the mass ratio of the first humectant, the thickener, the first emollient, the first emulsifier and the antioxidant is (2-8): (0.2-0.6): (0.1-0.5): (2-6): (0.1-0.4).

5. The moisturizing repair skin care product of claim 4, wherein the first emollient is selected from one or more of dioctyl carbonate, isooctyl palmitate, cetyl ethylhexanoate, allantoin.

6. The moisturizing repair skin care product of claim 3, wherein the phase B comprises a second emollient, a pH regulator, water, a second humectant and a second emulsifier, wherein the mass ratio of the second emollient, the pH regulator, the water, the second humectant and the second emulsifier is (0.5-2): (0.03-1.3): (0.5-1.5): (2-9): (0.3-1.5).

7. The moisturizing repair skin care product of claim 6, wherein the second emollient is selected from one or more of dimethicone, cyclopentadimethicone, polysiloxane-11, cyclopentadimethicone.

8. The moisturizing and repairing skin care product according to claim 3, wherein the phase C comprises a bacteriostatic agent, a third moisturizing agent, an anti-inflammatory agent and water, wherein the mass ratio of the bacteriostatic agent to the third moisturizing agent to the anti-inflammatory agent to the water is (0.01-0.2): (1-10): (0.5-4): (0.5-1.5).

9. The moisturizing repair skin care product of claim 8, wherein the third moisturizer is selected from one or more of hexylene glycol, butylene glycol, oat glucan, Ximin, sodium pyrrolidone carboxylate, saccharide isomerate.

10. The preparation method of the moisturizing repairing skin care product according to any one of claims 2 to 9, wherein the preparation method comprises the following steps: