CN115590772A - Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof - Google Patents
Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof Download PDFInfo
- Publication number
- CN115590772A CN115590772A CN202211350791.1A CN202211350791A CN115590772A CN 115590772 A CN115590772 A CN 115590772A CN 202211350791 A CN202211350791 A CN 202211350791A CN 115590772 A CN115590772 A CN 115590772A
- Authority
- CN
- China
- Prior art keywords
- oil
- parts
- seed oil
- essential oil
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/03—Liquid compositions with two or more distinct layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the technical field of skin care essence, in particular to double-layer essence oil with anti-wrinkle repairing effect and a preparation method thereof, wherein the double-layer essence oil comprises the following raw materials: jojoba seed oil, meadowfoam seed oil, monkey bushy seed oil, peony seed oil, small fruit coffee seed oil, wheat germ oil, camelina sativa seed oil, kiwi seed oil, linseed oil, perilla seed oil, bilberry seed oil, brickel fruit oil, sunflower seed oil, gardenia extract, rose extract, sodium chloride, gentian extract, emollient, humectant, preservative, antioxidant, compound essential oil, oil control component, pH regulator and deionized water. The double-layer essence oil disclosed by the invention comprises various oily raw materials, various water-based raw materials and an antioxidant combination, so that the purposes of regulating skin feel, preventing aging, resisting wrinkles, compacting, moisturizing, relieving and the like are achieved.
Description
Technical Field
The invention relates to the technical field of skin care essence, in particular to double-layer essence oil with an anti-wrinkle repairing effect and a preparation method thereof.
Background
With the continuous progress of social economy and the abundance of material life, the skin care product becomes one of the indispensable daily necessities of modern people. The skin care products have various types and functions, such as the effects of moisturizing, whitening, moisturizing, controlling oil, resisting aging, moistening skin, shrinking pores, removing blackheads, removing freckles, eliminating fat and the like, wherein the essential oil is taken as a skin care product rich in concentrated high-nutrition components, and is gradually the mainstream in the field of skin care products because of the remarkable multiple effects of resisting wrinkles, resisting aging, tightening, moisturizing, whitening and the like.
The essential oil is favored by people mainly because of the obvious characteristics of the formula. The essential oil is an oily substance similar to makeup removing oil or essential oil, and is the biggest difference with cosmetics such as water, milk, cream and the like. Most of skin care products with the conventional formula are emulsion liquid formed by emulsifying water, oil, an emulsifier and a thickening agent after mixing, the largest content of the emulsion liquid is water, and polyhydric alcohol humectants such as glycerin and butanediol are added, so that people often apply a thick layer of skin care product, but the experience that the moistening degree is not enough is found. As many functional components beneficial to the skin are oil-soluble and the oily raw materials are easier to be absorbed by the skin compared with the aqueous raw materials, the essential oil can be selected to moisturize under the condition that common milk and cream cannot meet the moisturizing requirement, and the essential oil is used for improving the problems of skin barrier damage, dryness, water shortage and the like.
According to the difference of skin feel of the essential oil, the essential oil can be divided into the following three types in terms of components:
1. the formula contains three or less components, even only one oily raw material without water or water-based raw materials, and the essential oil only contains one oily raw material, so that the effects of ageing resistance, wrinkle resistance, moisture retention, firming, skin barrier repair and the like cannot be considered;
2. the variety of oily raw materials in the formula is more than three, and no water or water-based raw materials exist, and the essential oil does not lack 'oil' on the skin of a person with oily skin, is directly smeared, and is like a thick oil film, so that discomfort can be caused;
3. the formula contains more than three oily raw materials, and contains water and aqueous raw materials, although the essential oil contains aqueous and oily raw materials, the formula of the existing product essential oil does not fully consider the interaction relationship between the aqueous and oily raw materials, and the essential oil still cannot effectively adjust the water-oil balance of a sebum membrane aiming at the skin state of external oil and dry internal oil.
Therefore, aiming at the defects of the existing essence oil products, developing a novel double-layer essence oil to meet the requirements of dry, neutral and mixed skin is a technical problem which needs to be solved urgently by the technical personnel in the field.
Disclosure of Invention
The first purpose of the invention is to provide a double-layer essential oil with anti-wrinkle repair effect, which can effectively maintain the stable state of a skin barrier and adjust the balance of water and oil of a dry skin sebum membrane in external oil;
the second purpose of the invention is to provide a preparation method of the double-layer essential oil with the anti-wrinkle repair effect, the preparation method is simple and efficient, and the prepared essential oil comprises both oily raw materials and aqueous raw materials, so that the requirements of various skin types such as dry, neutral and mixed skin can be met.
The invention provides double-layer essential oil with an anti-wrinkle repairing effect, which comprises the following raw materials in percentage by mass: 0.1-0.3 part of jojoba seed oil, 0.1-0.3 part of white pool flower seed oil, 0.1-0.3 part of Adiantum henryi seed oil, 0.1-0.3 part of peony seed oil, 0.03-0.1 part of California davidiana seed oil, 0.1-0.3 part of wheat germ oil, 0.1-0.3 part of camelina sativa seed oil, 0.03-0.1 part of Kiwi seed oil, 0.1-0.3 part of linseed oil, 0.1-0.3 part of perilla seed oil, 0.005-0.015 part of vaccinium myrtillus seed oil, 0.03-0.1 part of sunflower seed oil, 0.1-0.3 part of brier fruit oil, 0.005-0.015 part of gardenia extract, 30-45 parts of rose extract, 0.3-0.9 part of sodium chloride, 0.001-0.1 part of radix gentianae extract, 0.01-0.1 part of butanediol extract, 0.01-0.1 part of soft bark extract, 0.1-0.1.1.15-10 parts of a compound antioxidant, 0.1-10 parts of deionized water, 0.5-10 parts of pH regulator, 0.05-10 parts of pH regulator, 0.1-10 parts of deionized water, and 0.1-10 parts of compound humectant.
Wherein the rose extract comprises common rose extract and hybrid rose extract.
Preferably, the softening agent comprises any one or more of 0-8 parts of isohexadecane, 0-8 parts of squalane, 0-5 parts of undecane, 0-5 parts of tridecane, 0-4 parts of diethoxyethyl succinate and 0-5 parts of fermentation oil.
Preferably, the humectant comprises any one or more of 0-3 parts of glycerol, 0.02-0.06 part of ethylhexyl glycerol, 0-0.15 part of sodium hyaluronate, 1-4 parts of glyceryl polyether-26, 1-4 parts of butanediol, 0-1 part of 1, 2-pentanediol, 0-2 parts of trehalose, 0-2 parts of betaine, 0-2 parts of xylitol-based glucoside, 0-2 parts of dehydrated xylitol, 0-2 parts of xylitol and 0-0.01 part of acetylated sodium hyaluronate.
Preferably, the antioxidant comprises one or more of pentaerythritol (di-tert-butyl hydroxyhydrocinnamic acid) tetraester 0.08-0.12 parts, tocopherol acetate 0.3-0.7 parts, ascorbyl tetraisopalmitate 0.1-0.3 parts, and oil-soluble rosemary leaf extract 0.03-0.1 parts.
Preferably, the preservative component comprises any one or more of 0.6 part of 1, 2-hexanediol and 0.6 part of p-hydroxyacetophenone.
Preferably, in the technical solution, the oil-controlling component is succinic acid, and the pH adjuster is sodium hydroxide.
Preferably, the compound essential oil comprises any one or more of bergamot essential oil 0-0.01 parts, japanese pomelo essential oil 0-0.02 parts, geranium essential oil 0-0.01 parts, jasmine essential oil 0.01-0.1 parts, sandalwood essential oil 0-0.001 parts, carrot seed oil 0-0.002 parts, cedar essential oil 0-0.03 parts, north American juniper essential oil 0-0.02 parts, red tangerine peel oil 0-0.02 parts, pomelo peel oil 0-0.02 parts, cananga odorata essential oil 0-0.01 parts, eucalyptus globulus leaf essential oil 0-0.001 parts, orange leaf essential oil 0-0.001 parts and fennel essential oil 0-0.02 parts. In addition, the compound essential oil also comprises bergamot fruit oil.
The fermentation oil used in the invention is a fermentation product obtained by fermenting candida somnifera with glucose as a carbon source, and the specific rapeseed methyl oleate is derived from plant seed oils such as white chinquapin seed oil, jojoba seed oil, peony seed oil, macadamia chinensis seed oil, small fruit coffee seed oil, european cowberry seed oil, wheat germ oil, chinese gooseberry seed oil, camelina sativa seed oil, linseed oil and perilla seed oil.
The invention also discloses a preparation method of the double-layer essential oil, which comprises the following steps:
s1, sequentially adding squalane and isohexadecane into an oil phase tank, heating to 80-85 ℃, and stirring until the mixture is dissolved;
s2, adding an antioxidant, jojoba seed oil, white chinlon oil, papaveris seed oil, peony seed oil, sunflower seed oil, small fruit coffee seed oil, wheat germ oil, camelina sativa seed oil, kiwi seed oil, linseed oil, perilla seed oil, bridgkin fruit oil, european cowberry seed oil, fermentation oil and compound essential oil into the oil phase tank in the step S1 in sequence, stirring uniformly, and filtering to obtain an oil phase mixed solution, wherein the oil phase mixed solution is qualified when the sampling detection density is 0.80-0.84;
s3, sequentially adding deionized water and sodium hyaluronate into a production cylinder, and heating until the deionized water and the sodium hyaluronate are dissolved;
s4, sequentially adding the rose extract, the humectant, the gentian extract, the gardenia extract, the butanediol phellodendron amurense bark extract and succinic acid into the production cylinder in the step S3, and uniformly stirring;
s5, mixing and stirring deionized water, butanediol, 1, 2-pentanediol, 1, 2-hexanediol and p-hydroxyacetophenone until the deionized water, the butanediol, the 1, 2-pentanediol and the 1, 2-hexanediol are dissolved, adding the mixture into the production cylinder in the step S4, stirring uniformly, and adding sodium hydroxide to enable the pH value to be 5.5-7 to obtain a water phase mixed solution;
s6, uniformly mixing the oil phase mixed liquor and the water phase mixed liquor according to the weight ratio of 2;
wherein, the steps S1 and S3 have no requirement of sequence.
Preferably, in the present technical solution, step S3 specifically includes: sequentially adding water and sodium hyaluronate into production tank, heating to 80-85 deg.C, homogenizing to dissolve, stirring for 25-35min, and cooling to 40-50 deg.C.
Preferably, in step S6, sodium hydroxide is added to adjust the pH value to 5.5-7.0.
The functions and effects of the raw materials in the invention are as follows:
jojoba seed oil: the skin care product has good permeability, and the jojoba seed oil is added into the skin care product to increase the stability and help the skin to solve the problems of skin defects such as dryness, water shortage, roughness, darkness and the like; the jojoba seed oil contains abundant vitamins a, b and e, and minerals such as calcium, magnesium and the like, and the chemical molecular arrangement of the jojoba seed oil is very similar to that of human cortex, so that the jojoba seed oil is easy to be classified and absorbed by skin, and is suitable for all skin types, especially dry and dull skin types and skin types of whelks;
white Potentilla seed oil: the oil does not contain easily oxidized polyunsaturated fatty acid which is common in other vegetable oil, has the characteristics of oxidation resistance and stability of other vegetable oil; the product has rich texture, softness, moisture, quick absorption and good moisturizing performance, and can bring bright and smooth skin feeling to people;
monkey breads seed oil: the skin elasticity is increased, the reproduction of skin cells and tissues is promoted, pores are not blocked, and the normal breathing of the skin is not hindered;
and (3) peony seed oil: has effects in promoting generation of cathepsin and ceramide, and can be used as antioxidant in cosmetic for resisting aging; has strong inhibiting effect on staphylococcus, proteus, pseudomonas aeruginosa, escherichia coli, bacillus subtilis and the like, so the antibacterial and anti-inflammatory effects are achieved; has contraction effect on collagen fiber gel, and can be used as pore astringing agent;
and (3) small-fruit coffee seed oil: can improve the energy level of cells, slow down aging, help skin keep moisture for a long time, and can condition and tighten skin;
wheat germ oil: has antioxidant effect, can reduce lipid peroxide generation, promote skin moisture keeping effect, moisten skin, and delay aging; promoting metabolism and skin regeneration, removing wrinkle, preventing skin aging, and eliminating scar;
and (3) camelina sativa seed oil: skin conditioners, emollients;
kiwi seed oil: emollients, skin conditioners; the kiwi fruit contains a large amount of fruit acid, the fruit acid can inhibit the cohesion of keratinocyte and melanin, effectively dispel excessive cuticle or lighten black speck, and has obvious effect on improving dry and oily skin tissues; can promote the biosynthesis of cholesterol and has the function of moisturizing; promoting proliferation of epidermal cells, scavenging free radicals, and can be used in antiaging cosmetic;
linseed oil: a skin conditioning agent;
purple perilla seed oil: emollients, skin conditioners; has good moisturizing effect; can promote the generation of collagen, eliminate free radicals, and has anti-aging and anti-wrinkle effects;
european bilberry seed oil: can slow down the degradation of elastin and collagen, maintain the elasticity of skin, and can be used as cosmetic anti-wrinkle and anti-aging agent in combination with its antioxidant property; simultaneously can inhibit the activity of melanocytes and has certain whitening effect; can inhibit free histamine, and is used as antiallergic inhibitor; meanwhile, the composition also has certain anti-inflammatory effect;
sunflower seed oil: is an important base oil raw material of cosmetics and has the function of lubricating the skin; has activating effect on peroxidase-activated receptor, and has antiinflammatory effect for promoting skin wound healing; has certain inhibition effect on tyrosinase and certain whitening effect;
buric fruit oil: the emulsion prepared from the grease has good stability and good moisturizing effect;
gardenia extract: the skin moisturizing cream has excellent anti-inflammation and moisturizing effects, effectively improves the water retention of the skin, relieves sensitive and uncomfortable skin, forms a moisturizing barrier on the surface layer of the skin, reduces the loss of water and enables the skin to be rich in moisture and luster;
rose extract: the rose sugar has strong moisturizing and water locking functions, and can play a role in moisturizing and water locking for dry skin; the microelements such as selenium, zinc and copper contained in the rose can remove free radicals, so that the skin can recover moisture, tenderness and luster; it is rich in triterpenes, has skin aging delaying effect, and can effectively remove wrinkle;
and (3) gentian extract: has anti-inflammatory, moisture keeping, and antiaging effects;
isohexadecane: the main effect is the softening and refreshing experience;
squalane: squalane is a lipid closest to sebum of a human body, has strong affinity, can be integrated with the sebum membrane of the human body, and forms a natural barrier on the skin surface;
diethoxyethyl succinate: skin conditioning agent, emollient, water-soluble oil, and can improve smooth feeling and reduce greasy feeling of system;
glycerin: the moisturizer can moisten the skin and keep the skin moist for a long time;
ethyl hexyl glycerin: moisturizers, preservatives, skin feel modifiers;
sodium hyaluronate: the moisturizing and skin-care product can not only achieve the moisturizing effect, but also delay the aging of the skin, achieve the effects of maintaining beauty and keeping young, and achieve the repairing effect on damaged skin;
glyceryl polyether-26: the moisturizing agent can moisturize the skin to a certain extent, so that the skin becomes more mild and discomfort of the skin to the product is reduced;
butanediol: the moisturizing agent is fresh and cool in texture and not sticky, does not harm the skin after being used, and simultaneously can damage the living environment of bacteria, so that the moisturizing agent can not only moisturize the skin but also control the skin to grow more bacteria, and after being used, the skin is equivalently provided with a protective film to avoid water loss, so that the skin becomes more fresh and cool;
1, 2-pentanediol: the emollient and the humectant have the functions of moisturizing the skin and keeping moisture while preserving the skin, and can improve the skin feeling of the product, and have the problems of mildness, no stimulation and the like;
1, 2-hexanediol: the moisturizer is mainly used for improving the skin feel of the product;
xylitol-based glucoside: has good moisturizing effect, and can regulate the moisture content of skin;
dehydrated xylitol: moisturizers, skin conditioners;
xylitol: regulating the fine texture of the skin; regulating desquamation of skin; immediate and long lasting moisturization; strengthening the function of skin barrier; improving and balancing the effect of glycerol, and regulating the side effect of glycerol drying;
pentaerythritol (di-tert-butyl hydroxyhydrocinnamic acid) tetraester: antioxidant and skin conditioner, and has effects of scavenging free radicals, resisting oxidation, and preventing aging;
tocopherol acetate: belongs to the derivatives of vitamin E, has good antioxidant effect, and is a good nutritional moistening agent because of being oil-soluble natural substances; when added into skin care products, can prevent rancidity oxidation of grease and stabilize the grease; has good performance in moisturizing and maintaining connective tissues and protecting skin from ultraviolet rays; the composition can soften skin touch, keep skin moisture, promote wound healing, prevent inflammation, prevent skin roughness and chapping, and improve black spot;
and (3) tocopherol: fat-soluble vitamins, also one of the most important antioxidants;
ascorbic acid tetraisopalmitic acid: antioxidant, whitening agent, speckle removing agent and humectant, wherein the component is vitamin C derivative, and can inhibit activity of tyrosine ferment;
p-hydroxyacetophenone: simultaneously has the functions of antioxidation, sedation and relaxation; the composition has a synergistic effect when being compounded with other preservatives;
succinic acid: is dicarboxylic acid, has good skin tolerance and small irritation to skin, and can regulate sebum secretion and shrink pores;
sodium hydroxide: a pH adjusting agent;
phenoxyethanol: the antibacterial agent or the preservative can inhibit bacteria generated in the skin care product, reduce the problems caused by deterioration of the skin care product and prolong the service life of the skin care product;
compound essential oil: the compound essential oil consisting of the essential oil with specific composition is added into the double-layer essential oil, so that the double-layer essential oil can be endowed with the capability of adjusting the balance of water and oil of the outer oil and the inner dry skin sebum membrane, and can be suitable for dry, neutral, mixed oily skin and other skins.
The double-layer essential oil with the anti-wrinkle repair effect at least has the following technical effects:
1. the method selects 11 seed extracts of jojoba seed oil, chinaroot fruit seed oil, macadamia nut oil, peony seed oil, sunflower seed oil, small fruit coffee seed oil, camelina sativa seed oil, linseed oil, perilla seed oil, kiwi seed oil and European cowberry seed oil to be refined, so that the optimal ratio of linoleic acid to linolenic acid 1 in the outer oil and the inner dry skin can be simulated in a bionic mode, the linoleic acid and the linolenic acid are supplemented accurately, the anti-inflammatory performance of the skin is further improved, the stable state of the skin barrier is maintained, and the water-oil balance of the skin lipid membrane of the outer oil and the inner dry skin is adjusted;
2. according to the invention, the purple perilla seed oil, the meadowfoam seed oil, the kiwifruit seed oil, the ascorbic acid tetraisopalmitic acid and the pentaerythritol (di-tert-butyl hydroxy hydrocinnamic acid) tetraester antioxidant combination are preferably selected, and the raw materials are strongly combined to form a super antioxidant system, so that the double-layer essential oil is endowed with excellent antioxidant performance;
3. according to the invention, the xylitol-based glucoside, the dehydrated xylitol and the dehydrated xylitol are selected, the skin aquaporin AQP3 can be activated, sufficient water replenishing is realized from a basal layer to a horny layer, the sebum circulation of the skin is improved, and the effect of water-oil balance is achieved;
4. the rose extract is selected and refined to be matched with the succinic acid, so that the water-oil balance of the skin can be adjusted, and the natural pH balance of the skin can be maintained;
5. the double-layer essence oil disclosed by the invention comprises various oily raw materials and various water-based raw materials, so that the purposes of regulating skin feel and keeping the effects of preventing aging, resisting wrinkles, preserving moisture, whitening, removing freckles and the like are achieved, and the double-layer essence oil can have various effects on dry, neutral or mixed skin.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIGS. 1 to 3 are photographs showing the effects of improving pores by using a double-layer essential oil prepared in example 3 of the present invention (standard light source pattern photographs);
FIGS. 4 to 6 are photographs showing the effectiveness of the double-layer essential oil prepared in example 3 of the present invention in spot improvement;
fig. 7 to 9 are views showing examples (VC 20 light source mode photographs) of the effect of improving skin texture using the double-layer essential oil prepared in example 3 of the present invention.
Detailed Description
It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms also include the plural forms unless the context clearly dictates otherwise, and further, it is understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of the stated features, steps, operations, devices, components, and/or combinations thereof.
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The preparation method comprises the following steps:
s11, sequentially adding the materials in the first procedure into an oil phase tank, heating to 80 ℃, and stirring until the materials are completely dissolved and transparent.
S12, sequentially adding the materials in the second procedure into the oil phase tank, uniformly stirring, sampling, detecting, and filtering after qualification to obtain an oil phase mixed solution;
s13, sequentially adding the materials in the third procedure into a production cylinder, heating to 80 ℃, homogenizing uniformly until the materials are completely dissolved and transparent, keeping the temperature and stirring for 30min, and cooling to 45 ℃;
s14, adding the materials of the fourth process into the production cylinder in sequence, and stirring uniformly.
S15, mixing and stirring the materials in the fifth procedure in a clean container until the materials are completely dissolved, adding the materials into the production cylinder in the step S4, uniformly stirring, adding sodium hydroxide, and adjusting the pH value to 5.5-7.0 to obtain a water phase mixed solution;
and S16, uniformly mixing the oil phase mixed solution and the water phase mixed solution according to the weight ratio of 2.
Example 2
The preparation method comprises the following steps:
s21, sequentially adding the materials in the first procedure into an oil phase tank, heating to 85 ℃, and stirring until the materials are completely dissolved and transparent.
S22, sequentially adding the materials in the second procedure into the oil phase tank, uniformly stirring, sampling, detecting, and filtering after qualification to obtain an oil phase mixed solution;
s23, sequentially adding the materials in the third procedure into a production cylinder, heating to 85 ℃, homogenizing uniformly until the materials are completely dissolved and transparent, keeping the temperature and stirring for 30min, and cooling to 45 ℃;
and S24, sequentially adding the materials in the fourth process into the production cylinder, and uniformly stirring.
S25, mixing and stirring the materials in the fifth procedure in a clean container until the materials are completely dissolved, adding the materials into the production cylinder in the step S4, uniformly stirring, and adding sodium hydroxide to adjust the pH value to 5.5-7.0 to obtain a water phase mixed solution;
and S26, uniformly mixing the oil-phase mixed solution and the water-phase mixed solution according to the weight ratio of 2.
Example 3
The preparation method comprises the following steps:
s31, sequentially adding the materials in the first procedure into an oil phase tank, heating to 85 ℃, and stirring until the materials are completely dissolved and transparent.
S32, sequentially adding the materials in the second procedure into the oil phase tank, uniformly stirring, sampling, detecting, and filtering after qualification to obtain an oil phase mixed solution;
s33, sequentially adding the materials in the third procedure into a production cylinder, heating to 85 ℃, homogenizing uniformly until the materials are completely dissolved and transparent, keeping the temperature and stirring for 30min, and cooling to 45 ℃;
and S34, sequentially adding the materials in the fourth process into the production cylinder, and uniformly stirring.
S35, mixing and stirring the materials in the fifth procedure in a clean container until the materials are completely dissolved, adding the materials into the production cylinder in the step S4, uniformly stirring, and adding sodium hydroxide to adjust the pH value to 5.5-7.0 to obtain a water phase mixed solution;
and S36, uniformly mixing the oil phase mixed solution and the water phase mixed solution according to the weight ratio of 2.
Comparative example 1
The patent publication with application number of 202110986530.8 entitled "a vegetable oil composition with skin aging delaying effect and its application" is used as reference.
Comparative example 2
The substitute methyl glucitol polyether-20 of xylitol-based glucoside, anhydroxylitol and xylitol was selected, the amount of which was 2%, and other raw materials and preparation methods were the same as those of example 3.
Comparative example 3
Methyl propylene glycol was used instead of succinic acid, and other raw materials and preparation methods were the same as in example 3.
Test example 1 anti-wrinkle and tightening efficacy test
The test method comprises the following steps:
characterized by evaluating the inhibition of elastase by the test samples. Elastase is synthesized and secreted mainly by fibroblasts and is capable of degrading elastin in the skin resulting in skin aging. The experimental principle of inhibiting the elastase is that the porcine pancreatic elastase and an enzyme substrate are subjected to catalytic reaction, the absorbance changes after an active substance is added, and the inhibition rate of the elastase inhibitor is reflected by the change of the absorbance.
The test refers to a laboratory method (HMC-WI-028 elastase inhibition rate), the results of elastase inhibition rate tests on a test sample and a negative control are compared, and if the inhibition rate of the test sample is higher than that of the negative control and has significant difference (P is less than 0.05), the test sample can be considered to have certain anti-wrinkle and tightening effects.
Table 1 wrinkle resistance, tightening efficacy test results
| Product(s) | Test results (%) | P value |
| Example 1 | 45.49 | <0.05 |
| Example 2 | 50.36 | <0.05 |
| Example 3 | 46.24 | <0.05 |
| Comparative example 1 | 20.12 | <0.05 |
| Comparative example 2 | 43.56 | <0.05 |
| Comparative example 3 | 42.29 | <0.05 |
| Negative control | -9.150±8.319 | <0.05 |
| Positive control | 71.739±3.394 | <0.05 |
As can be seen from table 1, the inhibition ratio of the positive control elastase is greater than 50%, the reaction system is effective, when the sample is diluted into 0.1% aqueous solution, the inhibition ratio of the elastase is 45.49%, and the significant difference (P < 0.05) is realized compared with the negative control, which indicates that the sample has certain anti-wrinkle and tightening effects.
Test example 2 product oxidation resistance test
By testing the double-layer essential oil on DPPH free radical and ABTS + The scavenging ability of free radicals, and the corresponding antioxidant efficacy thereof were tested, and the test results are shown in table 2.
The test method comprises the following steps:
0.0100g of DPPH powder (molecular weight is about 394) is precisely weighed and placed in a volume of 250mL, dissolved by a proper amount of 95% ethanol, and then the volume is determined to be 250mL by 95% ethanol, thus obtaining the DPPH reagent with the concentration of 0.1 mmol/L.
Sequentially adding 4.0ml of prepared DPPH solution and 1.0ml of 95% ethanol into a 10ml test tube, mixing, shaking, reacting in dark for 30min, stabilizing, measuring absorbance at 517nm with 95% ethanol as reference, and recording as A 0 。
Sequentially adding 4.0ml 95% ethanol solution and 1.0ml to-be-detected sample solution into 10ml test tube, mixing, shaking, reacting in dark for 30min, stabilizing, measuring absorbance at 517nm with 95% ethanol as reference, and recording as A s 。
Sequentially adding 4.0ml of prepared DPPH solution and 1.0ml of sample solution to be detected into a 10ml test tube, mixing, shaking, reacting in a dark place for 30min, stabilizing, measuring the light absorption value at 517nm with 95% ethanol as reference, and recording as A r 。
The same sample was tested 3 times and the clearance was calculated according to the following formula.
DPPH radical clearance (%) = {1- (a) r -A s )/A 0 }*100％
Wherein A is r The absorbance of the DPPH solution after the antioxidant is added for reaction;
A s absorbance of a solution of antioxidant and 95% ethanol alone without DPPH;
A 0 absorbance of DPPH and 95% ethanol alone was added without antioxidant.
Taking 4ml of ABTS + Working solution → 1mL sample → mix 10s → keep standing in the dark at 25 ℃ for 6min → measure absorbance at 734 nm. A sample of 4mLPBS +1mL is used as a reference Sample(s) ；
Taking 4ml of ABTS + Working solution → 1mLPBS → mixed 10s → kept standing at 25 ℃ for 6min in the dark → absorbance is measured at 734 nm. Using PBS as reference, note A o 。
ABTS + Radical clearance (%) = (a) 0 -A Sample(s) )/A 0 }*100％
TABLE 2 substances in relation to DPPH radical and ABTS + Cleaning capability of
| Concentration of | DPPH clearance (%) | ABTS + clearance (%) |
| Vitamin C | 99.21 | 99.52 |
| Example 1 | 89.36 | 95.23 |
| Example 2 | 87.42 | 93.18 |
| Example 3 | 85.46 | 92.22 |
| Comparative example 1 | 77.09 | 79.37 |
| Comparative example 2 | 78.2 | 85.28 |
| Comparative example 3 | 79.35 | 85.34 |
Test example 3 product efficacy test
91 volunteers aged 26-65, 13 men and 78 women were recruited into 7 groups of 13 persons each, and 1-7 groups used example 1, example 2, example 3, control 1, control 2, control 3, blank sample, respectively. The efficacy of the samples was evaluated by instrumental testing by comparing the skin values before and after using the samples, the test methods and items are shown in table 3:
blank control: no treatment is done and the sample is not smeared.
TABLE 3 test methods and items
Wherein D0 refers to the first day of visit of the subject, D7 refers to the day of visit of the subject after 7 days of sample use, D14 refers to the day of visit of the subject after 14 days of sample use, and D28 refers to the day of visit of the subject after 28 days of sample use.
1. Water content of horny layer of skin
TABLE 4 skin stratum corneum moisture content
Note: percent improvement (%) = (test value N days using sample-test value before use)/test value before use%
TABLE 5 Perdermic Water loss Rate
Note: (ii) improvement rate (%) = (test value N days using sample-test value before use)/test value before use × 100%
TABLE 6 skin oil content test results
Note: percent improvement (%) = (using sample N days test value-before use test value)/before use test value 100%
TABLE 7 skin roughness parameter SEr value test results
Note: (ii) improvement (%) = (test value N days using sample-test value before use)/test value before use 100%
TABLE 8 skin wrinkle parameter SEw value test results
Note: percent improvement (%) = (test value N days using sample-test value before use)/test value before use%
TABLE 10 results of the skin elasticity R2 value test
Note: (ii) improvement rate (%) = (test value N days using sample-test value before use)/test value before use × 100%
Table 10 skin pore area ratio test
Note: improvement (%) = (test value N days using sample-test value before use)/test value before use = 100%
8. Skin firmness
Table 11 skin firmness test results
Note: improvement (%) = (test value N days using sample-test value before use)/test value before use = 100%
In conclusion, the double-layer essential oil has good effects of moisturizing, firming skin, shrinking pores, resisting wrinkles and lines, and can effectively improve skin glossiness, reduce skin oil, reduce roughness and enable skin to be fine and smooth.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and these modifications or substitutions do not depart from the spirit of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. The double-layer essence oil with the anti-wrinkle repairing effect is characterized by comprising the following raw materials in percentage by mass: 0.1-0.3 part of jojoba seed oil, 0.1-0.3 part of white pool flower seed oil, 0.1-0.3 part of Adiantum henryi seed oil, 0.1-0.3 part of peony seed oil, 0.03-0.1 part of California davidiana seed oil, 0.1-0.3 part of wheat germ oil, 0.1-0.3 part of camelina sativa seed oil, 0.03-0.1 part of Kiwi seed oil, 0.1-0.3 part of linseed oil, 0.1-0.3 part of perilla seed oil, 0.005-0.015 part of vaccinium myrtillus seed oil, 0.03-0.1 part of sunflower seed oil, 0.1-0.3 part of brier fruit oil, 0.005-0.015 part of gardenia extract, 30-45 parts of rose extract, 0.3-0.9 part of sodium chloride, 0.001-0.1 part of radix gentianae extract, 0.01-0.1 part of butanediol extract, 0.01-0.1 part of soft bark extract, 0.1-0.1.1.15-10 parts of a compound antioxidant, 0.1-10 parts of deionized water, 0.5-10 parts of pH regulator, 0.05-10 parts of pH regulator, 0.1-10 parts of deionized water, and 0.1-10 parts of compound humectant.
2. The double-layer essence oil according to claim 1, wherein the emollient comprises any one or more of isohexadecane 0-8 parts, squalane 0-8 parts, undecane 0-5 parts, tridecane 0-5 parts, diethoxyethyl succinate 0-4 parts, and fermentation oil 0-5 parts.
3. The double-layer essential oil according to claim 1, wherein the moisturizer comprises any one or more of 0-3 parts of glycerin, 0.02-0.06 parts of ethylhexylglycerin, 0-0.15 parts of sodium hyaluronate, 1-4 parts of glyceryl polyether, 1-4 parts of butanediol, 0-1 part of 1, 2-pentanediol, 0-2 parts of trehalose, 0-2 parts of betaine, 0-2 parts of xylitol-based glucoside, 0-2 parts of dehydrated xylitol, 0-2 parts of xylitol, and 0-0.01 parts of acetylated sodium hyaluronate.
4. The bi-layer essential oil according to claim 1, wherein the antioxidant comprises any one or more of pentaerythritol (di-t-butyl hydroxyhydrocinnamate) tetraester 0.08-0.12 parts, tocopherol acetate 0.3-0.7 parts, ascorbyl tetraisopalmitate 0.1-0.3 parts, and oil-soluble rosemary leaf extract 0.03-0.1 parts.
5. The dual-layer essential oil according to claim 1, wherein the preservative component comprises any one or more of 0.6 parts of 1, 2-hexanediol and 0.6 parts of p-hydroxyacetophenone.
6. The bi-layer essential oil according to claim 1, wherein the oil-controlling component is succinic acid, and the pH regulator is sodium hydroxide.
7. The dual-layer essential oil of claim 1, wherein the compound essential oil comprises any one or more of bergamot essential oil 0-0.01 parts, japanese pomelo essential oil 0-0.02 parts, geranium essential oil 0-0.01 parts, jasmine essential oil 0.01-0.1 parts, sandalwood essential oil 0-0.001 parts, carrot seed oil 0-0.002 parts, cedar essential oil 0-0.03 parts, north American juniper essential oil 0-0.02 parts, red tangerine peel oil 0-0.02 parts, pomelo peel oil 0-0.02 parts, cananga odorata essential oil 0-0.01 parts, eucalyptus globulus leaf essential oil 0-0.001 parts, orange leaf essential oil 0-0.001 parts and fennel essential oil 0-0.02 parts.
8. The method for preparing the double-layer essential oil of any one of claims 1 to 7, which is characterized by comprising the following steps of:
s1, sequentially adding squalane and isohexadecane into an oil phase tank, heating to 80-85 ℃, and stirring until the mixture is dissolved;
s2, sequentially adding an antioxidant, jojoba seed oil, white chinlon oil, papaveris seed oil, peony seed oil, sunflower seed oil, small fruit coffee seed oil, wheat germ oil, camelina sativa seed oil, kiwi seed oil, linseed oil, perilla seed oil, bridgkin fruit oil, european cowberry seed oil, fermentation oil and compound essential oil into the oil phase tank in the step S1, uniformly stirring, sampling, detecting and filtering after qualification to obtain an oil phase mixed solution;
s3, sequentially adding deionized water and sodium hyaluronate into a production cylinder, and heating until the deionized water and the sodium hyaluronate are dissolved;
s4, sequentially adding the rose extract, the humectant, the gentian extract, the gardenia extract, the butanediol phellodendron amurense bark extract and succinic acid into the production cylinder in the step S3, and uniformly stirring;
s5, mixing and stirring deionized water, butanediol, 1, 2-pentanediol, 1, 2-hexanediol and p-hydroxyacetophenone until the deionized water, the butanediol, the 1, 2-pentanediol and the 1, 2-hexanediol are dissolved, adding the mixture into the production cylinder in the step S4, stirring uniformly, and adding sodium hydroxide to obtain a water-phase mixed solution;
s6, uniformly mixing the oil phase mixed solution and the water phase mixed solution according to the weight ratio of 2;
wherein, the steps S1 and S3 have no requirement of the sequence.
9. The method according to claim 8, wherein step S3 specifically comprises: sequentially adding water and sodium hyaluronate into production cylinder, heating to 80-85 deg.C, homogenizing to dissolve, stirring for 25-35min, and cooling to 40-50 deg.C.
10. The method according to claim 8, wherein in step S6, sodium hydroxide is added to adjust the pH to 5.5 to 7.0.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211350791.1A CN115590772A (en) | 2022-10-31 | 2022-10-31 | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211350791.1A CN115590772A (en) | 2022-10-31 | 2022-10-31 | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115590772A true CN115590772A (en) | 2023-01-13 |
Family
ID=84851721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211350791.1A Pending CN115590772A (en) | 2022-10-31 | 2022-10-31 | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115590772A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117695168A (en) * | 2024-02-04 | 2024-03-15 | 广州优理氏生物科技有限公司 | Composition with anti-aging repairing effect, freeze-dried powder and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000212027A (en) * | 1999-01-26 | 2000-08-02 | Kose Corp | Preparation for external use for skin |
| CN109498509A (en) * | 2018-11-26 | 2019-03-22 | 张庆 | A kind of stoste and preparation method thereof with a variety of skin effects |
| CN110384634A (en) * | 2019-09-06 | 2019-10-29 | 广州留今科学研究有限公司 | A kind of man's shower cream and preparation method thereof of more foam easy cleanings |
| CN113712862A (en) * | 2021-08-26 | 2021-11-30 | 北京茂思商贸有限公司 | Vegetable oil composition with skin aging delaying effect and application thereof |
-
2022
- 2022-10-31 CN CN202211350791.1A patent/CN115590772A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000212027A (en) * | 1999-01-26 | 2000-08-02 | Kose Corp | Preparation for external use for skin |
| CN109498509A (en) * | 2018-11-26 | 2019-03-22 | 张庆 | A kind of stoste and preparation method thereof with a variety of skin effects |
| CN110384634A (en) * | 2019-09-06 | 2019-10-29 | 广州留今科学研究有限公司 | A kind of man's shower cream and preparation method thereof of more foam easy cleanings |
| CN113712862A (en) * | 2021-08-26 | 2021-11-30 | 北京茂思商贸有限公司 | Vegetable oil composition with skin aging delaying effect and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 北京茂思商贸有限公司: "阿芙十一籽发酵油精华液", pages 1, Retrieved from the Internet <URL:https://hzpba.nmpa.gov.cn/gccx/chakan.html?prodId=1136667889357553664&gb=G> * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117695168A (en) * | 2024-02-04 | 2024-03-15 | 广州优理氏生物科技有限公司 | Composition with anti-aging repairing effect, freeze-dried powder and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110787093B (en) | Double-dosage essence and preparation method thereof | |
| CN110974767A (en) | Composition for skin barrier regeneration repair and application thereof | |
| CN114159347B (en) | Composition with whitening and repairing effects and preparation method and application thereof | |
| CN110638707A (en) | Eye care cream and preparation method thereof | |
| CN113693962A (en) | Fibronectin-containing multiple protein repair composition and preparation method thereof | |
| JP5253862B2 (en) | Melanin production inhibitor / collagen production promoter | |
| CN113018231A (en) | Cosmetic oil capable of repairing skin barrier | |
| CN111773122A (en) | Heating mask with moistening effect and preparation method thereof | |
| KR20140060928A (en) | Skin external composition containing thioredoxin | |
| CN115590772A (en) | Double-layer essential oil with anti-wrinkle repairing effect and preparation method thereof | |
| CN104188859A (en) | Anti-wrinkle skin-tendering emulsion containing natural component extracts and preparation method thereof | |
| CN112353705A (en) | Cosmetic composition, preparation method thereof and cosmetic with wrinkle removing and aging delaying effects | |
| CN113616541B (en) | Double-layer essence and preparation method thereof | |
| CN115645293A (en) | Essence oil with antioxidant effect and preparation method and application thereof | |
| CN115813774A (en) | Water-oil double-layer refined composition with whitening effect and preparation method and application thereof | |
| KR101775485B1 (en) | Cosmetic composition containing fermentative extract of Spatholobus suberectus Dunn as active ingredient | |
| CN115154375A (en) | Stable cleaning composition with repairing and relieving effects | |
| CN111494270A (en) | Multi-effect relieving essence composition, multi-effect relieving essence lotion and preparation method of multi-effect relieving essence lotion | |
| CN113413354A (en) | Active dressing with wound surface repairing and/or barrier regenerating effects, application of active dressing and skin repairing BB cream | |
| CN111265431A (en) | Moisturizing and repairing composition | |
| CN113384483A (en) | Composition for improving skin elasticity and delaying aging and preparation method thereof | |
| KR102108116B1 (en) | A cosmetic composition comprising a natural component and an oil component | |
| CN112402335A (en) | Water-bursting powder and preparation method thereof | |
| KR20160020038A (en) | Cosmetic Composition containing Frangipani Oil or Fermented Frangipani Oil | |
| KR20210001045A (en) | A cosmetic composition having prevention of lipid peroxidation, improved damaged skin and soothing effect on redness of skin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |