CN108354865A - Wrinkle antiallergic composition and preparation method thereof is removed in a kind of moisturizing - Google Patents
Wrinkle antiallergic composition and preparation method thereof is removed in a kind of moisturizing Download PDFInfo
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- CN108354865A CN108354865A CN201810341253.3A CN201810341253A CN108354865A CN 108354865 A CN108354865 A CN 108354865A CN 201810341253 A CN201810341253 A CN 201810341253A CN 108354865 A CN108354865 A CN 108354865A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/9789—Magnoliopsida [dicotyledons]
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Abstract
The invention discloses a kind of moisturizings to remove wrinkle antiallergic composition, including following components in percentage by weight：Biologically active polypeptide 0.002 0.5%, skin conditioning agent 5 15%, matrix components 10 30%, surplus are cold spring water.The present invention adds cold spring water of the acquisition from Wudalianchi Volcanic, rich in the comparable trace element of human body requirements ratio, human digestive function and body water-electrolyte metabolism can effectively be adjusted, body biological enzyme system function and internal system can be improved, it has good curative effect with good medical value, to skin disease；Trace element in biologically active polypeptide and Wudalianchi cold spring water is used in combination, peptide molecule is combined with ionic forms trace element, penetrate into epidermal cell, pass through blood microcirculation, it is sent to skin texture, skin texture cell is activated, has the effect of moisturizing moisturizing, crease-resistant, antiallergic, anti-inflammatory and light spot；It is applicable not only to general crowd, moreover it is possible to further improve skin disease.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to wrinkle antiallergic composition and its preparation side are gone in a kind of moisturizing
Method, and include the skin care item of the moisturizing wrinkle-smoothing composition.
Background technology
With being incremented by for age, the increase of operating pressure, the pollution of electronic product radiation increased with ambient enviroment is arrived
After certain age, the grease and collagen of skin skin are all being lost in, and aging gradually aggravates, thus face will appear microgroove,
The problems such as loose, obscure dark yellow, pigementation.Therefore, U.S. is pursued, public eternal theme is become.As people live
Beautiful is most asked in the raising of gentle economic level, and skin care item and cosmetics receive the favor of many female friends.
Existing market has various skin care item, but substantially skin care item will remind user to notice that determination on probation is
It is not no to have allergic phenomena, then be applied to face, therefore for skin allergy or have the crowd of skin disease, they cannot directly use
These skin care item.Because during use, these skin care item have certain irritation to skin, can make skin allergy, not only
The effect of skin care is not had, or even with opposite side effect.Therefore, for the crowd of skin allergy, want to buy a be suitble to
Skin care item be a more difficult completion task.
It is therefore desirable to develop a kind of moisturizing to remove the antianaphylactic skin care item that wrinkle, the person that makes skin allergy also can normally use should
Skin care item, and can further improve the allergic condition of allergic skin after use, enhance the barrier function of skin.
Invention content
The object of the present invention is to provide a kind of compositions for having effects that good moisturizing and going wrinkle antiallergy, and the composition is not
It is only applicable to general crowd to use, moreover it is possible to be suitable for skin allergy person, can further improve the mistake of allergic skin after use
Quick situation enhances the barrier function of skin.
The technical solution adopted by the present invention is：Wrinkle antiallergic composition is removed in a kind of moisturizing, including following weight percent
Component：
Biologically active polypeptide 0.002-0.5%,
Skin conditioning agent 5-15%,
Matrix components 10-30%,
Surplus is cold spring water.
Preferably, wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.01-0.1%,
Skin conditioning agent 8-12%,
Matrix components 12-25%,
Surplus is cold spring water.
Preferably, wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.05-0.3%,
Skin conditioning agent 10-12%,
Matrix components 15-20%,
Surplus is cold spring water.
Preferably, by weight percentage, it further includes the preservative of 0.1-1% that wrinkle antiallergic composition is removed in the moisturizing,
The preservative is parahydroxyacet-ophenone.
Preferably, the biologically active polypeptide is selected from palmityl tetrapeptide -7, palmityl tripeptides -1, palmityl tripeptides -3 and six
Win one or more of peptide.
Preferably, the total weight of wrinkle antiallergic composition is gone by moisturizing, the biologically active polypeptide is by following weight hundred
The group of ratio is divided to be grouped as：0.0008-0.2% palmityls tetrapeptide -7,0.0002-0.1% palmityl tripeptides -1,0.0005-0.1%
Palmityl tripeptides -3 and 0.0005-0.1% Argirelines.
Palmityl tetrapeptide -7 is used in beauty product can inhibit the generation of excessive cell interleukin.This interleukin meeting
The acute inflammatory reaction for triggering body causes glycosylation to damage, that is, glucose and protein cross and cohesive process is caused to damage,
Make the hardening of tissue, the support system of skin, such as collagen, elastin laminin and other protein are adversely affected, to
It is uneven to form wrinkle, relaxation and the colour of skin.And palmityl tetrapeptide -7 is easy to be absorbed by the skin, and has and eliminates the potential inflammation of skin,
The effect of antiallergic is generated to mitigating wrinkle, and restoring skin vigor has remarkable efficacy, can promote the growth of connective tissue, increases
Palmitoyl tripeptide 3 and four victory peptides are used in combination, can effectively facilitate into when collagen increases by the generation of the collagen in skin
The synthesis of collagen and hyaluronic acid, crease-resistant in fibrocyte, anti-inflammatory, the significant effect of antiallergic.
Palmityl tripeptides -1 and the fat-soluble of palmityl tripeptides -3 can be preferably absorbed by the skin by force, enhance face elasticity,
Promote cell activity, improve skin water content, improve the colour of skin, has to skin cell renewal, reparation, collagen synthesis apparent
Regulation and control and facilitation.The effect of palmitoyl tripeptide 3, can reach the cosmetic result of ossein injection.
Argireline is the core component of top skin care item, it is a kind of biologically active polypeptide, which can both reduce existing
Facial wrinkles, and new wrinkle can be effectively prevent to generate.Argireline can slow down the strength of contraction of muscle, allow loosening all muscles,
The activity of elastin can be increased, make face with microgroove, effective reorganization collagen elastic force is eliminated by reducing the generation of dynamic line
Lines loosen, smooth out wrinkles and improvement relaxation.By Argireline for being used as crease-resistant ingredient, excellent in cosmetics.
Argireline is a type creotoxin ingredient, has creotoxin repertoire, and is free of any toxicity, is non-toxic substance
Matter.Its main ingredient is the biogenetic products being composed of six amino acid ranges, although often quilt and clostridium botulinum are mentioned in the same breath,
But their mechanism is entirely different.Argireline can intercept the signal of contraction of muscle, mitigate the power of contraction of muscle, and then improve
The depth and length of microgroove.It has replaced creotoxin to become noticeable beauty new lover.
Preferably, the skin conditioning agent is selected from Rosa Damascana, hyaluronic acid, Radix Gentianae extract and chlorella extract
It is one or more.
Preferably, the total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following weight percent
The group of ratio is grouped as：0.5-1% Rosa Damascanas, 2-8% hyaluronic acids, 1-3% Radix Gentianae extracts and the extraction of 1.5-3% chlorellas
Object.
Preferably, the matrix components are selected from one or both of butanediol and glycerine polymethacrylates.
Preferably, the cold spring water is Wudalianchi Volcanic cold spring water, and pH value 6.5-7.5, micronutrient levels is：
Potassium 75-90mg/L, iron 0.1-0.5mg/L, sodium 60-75mg/L, cobalt 0.06-0.07mg/L, magnesium 75-90mg/L, iodine 0.01-
0.016mg/L, calcium 95-110mg/L, selenium 0.001-0.002mg/L, zinc 0.06-0.08mg/L, metasilicic acid 65-75mg/L, lithium
0.02-0.05mg/L, carbon dioxide 1300-1600mg/L, strontium 1.01-1.30mg/L.
The common skin-protection product of existing market is only applicable to the use of non-skin allergy sufferers, for having skin allergy or skin
The crowd of skin disease, they cannot directly use these skin care item, and the skin-protection product of the present invention had both had the work(of skin care
Effect, moreover it is possible to the effect for the treatment of allergic skin problem and improving allergic skin problem, equivalent medical aqua, but medicinal aqua is boundary again
It is scheduled on pharmaceuticals industry, cannot daily or be commonly used, and the raw material that we use, cold spring water is because of its distinctive micronutrient levels
With surprising consistent of blood of human body ratio, using polypeptide small molecule technology, by these elements and ingredient to skin beneficiating, infiltration
Epidermis lower layer reaches moisturizing moisturizing, goes antianaphylactic effect of wrinkling, the aging of delaying skin, moreover it is possible to improve skin disease problem, increase
Add the barrier function of skin.
Wudalianchi Volcanic cold spring Shuifu County containing a variety of heavy carbonate and potassium, sodium, calcium, four kinds of macroelements of magnesium and barium, tin,
Fluorine, silicon, strontium, iron, chromium, zinc, cobalt, molybdenum, selenium, the kind trace element of nickel more than ten, salt ratio and human body fluid, blood different kinds of ions
Ratio is almost the same, can very well supplement the essential trace elements of the human body, meet the needs of health, and can also effectively adjust
Section human digestive function and body water-electrolyte metabolism, suitable ferrous ion are conducive to direct suction of the human body to hematopoietic element (iron)
It receives, the content of product intermediate ion calcium is especially high (95-110mg/L), and needed by human body calcium can be supplemented using the infiltration of technology peptide molecule
Matter, and body biological enzyme system function and internal system can be improved, especially more preferably to skin disease and other effects, moreover it is possible to improve machine
Body biology enzyme system etc. many diseases.
Preferably, the total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following weight percent
Group be grouped as：3-15% butanediols and 7-15% glycerine polymethacrylates.
The present invention also provides the preparation methods that wrinkle antiallergic composition is removed in moisturizing, include the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
The present invention also provides a kind of skin care item, the skin care item include that wrinkle antiallergic composition is removed in moisturizing, wherein by weight
Percentage meter is measured, the moisturizing goes wrinkle antiallergic composition to account for the 5-85% of skin care item total weight.It is furthermore preferred that the skin care item
Go wrinkle antiallergic composition, wherein percentage, the moisturizing that wrinkle antiallergic composition is gone to account for skin care item including moisturizing
The 20-80% of total weight；The skin care item include that wrinkle antiallergic composition, wherein percentage, the guarantor are gone in moisturizing
The wet 25-75% for going wrinkle antiallergic composition to account for skin care item total weight；The skin care item include that wrinkle antiallergic composition is removed in moisturizing,
Wherein percentage, the moisturizing go wrinkle antiallergic composition to account for the 30-70% of skin care item total weight.
Preferably, the skin care item include toner, lotion, Essence, face cream, eye cream, facial cleanser, foundation emulsion and isolation
Breast.
Trace element in biologically active polypeptide and Wudalianchi cold spring water is used in combination the present invention, by cold spring water
Functional trace element adjusts human body nerve ending, and peptide molecule is combined with ionic forms trace element, penetrates into epidermis
Functional element is sent to skin texture, activates skin texture cell, adjust human body by cell by blood microcirculation
Inner tissue's structural framing chain, absorbs crease-resistant, antiallergic, and the active principles such as anti-inflammatory reach moisturizing, crease-resistant, antiallergic, anti-inflammatory and light spot
Effect.
For product of the present invention on the basis of the function of common Moisturizer, crowd of the exploitation comprising sensitive skin can also
The skin care item used not only have good moisturizing whitening spot-removing and other effects, also have antiallergic performance, to the wrinkle being broken
Line has good reparation effect, greatly improves the ability of removal fine wrinkles, and there is the skin-protection product of preparation excellent moisturizing to mend
Water, light spot effect, anti-inflammatory effect.
The beneficial effects of the invention are as follows：It is rich from the cold spring water of Wudalianchi Volcanic, the cold spring water that the present invention adds acquisition
Containing trace elements such as potassium, sodium, calcium, magnesium, iron, manganese, fluorine, chromium, zinc, copper, barium, and these micronutrient levels and human body requirements ratio
Quite, human digestive function and body water-electrolyte metabolism can be effectively adjusted, body biological enzyme system function and endocrine can be improved
System has good curative effect with good medical value to skin disease；By biologically active polypeptide and Wudalianchi cold spring
Trace element is used in combination in water, and peptide molecule is combined with ionic forms trace element, epidermal cell is penetrated into, passes through blood
Functional element is sent to skin texture, activates skin texture cell by liquid microcirculation, has moisturizing moisturizing, crease-resistant, anti-
The effect of quick, anti-inflammatory and light spot；The skin care item of the present invention are applicable not only to general crowd, to skin sensitivity person or have skin
The crowd of disease is also suitable, moreover it is possible to further improve skin disease.
Specific implementation mode
Embodiment 1
Wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.01%,
Skin conditioning agent 5%,
Matrix components 12%,
Preservative (parahydroxyacet-ophenone) 0.2%,
Surplus is Wudalianchi Volcanic cold spring water.
By moisturizing go wrinkle antiallergic composition total weight, the biologically active polypeptide by following weight percent group
It is grouped as：0.001% palmityl tetrapeptide -7,0.002% palmityl tripeptides -1,0.005% palmityl tripeptides -3 and 0.002% 6
Win peptide.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following components in percentage by weight
Composition：0.5% Rosa Damascana, 2% hyaluronic acid, 1% Radix Gentianae extract and 1.5% chlorella extract.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following components in percentage by weight group
At：5% butanediol and 7% glycerine polymethacrylates.
The preparation method of wrinkle antiallergic composition is gone in a kind of moisturizing, is included the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
Embodiment 2
Wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.05%,
Skin conditioning agent 7%,
Matrix components 15%,
Preservative to (hydroxy acetophenone) 0.3%,
Surplus is Wudalianchi Volcanic cold spring water.
By moisturizing go wrinkle antiallergic composition total weight, the biologically active polypeptide by following weight percent group
It is grouped as：0.02% palmityl tetrapeptide -7,0.01% palmityl tripeptides -1,0.01% palmityl tripeptides -3 and 0.01% 6 victory
Peptide.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following components in percentage by weight
Composition：0.5% Rosa Damascana, 3% hyaluronic acid, 1.5% Radix Gentianae extract and 2% chlorella extract.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following components in percentage by weight group
At：5% butanediol and 10% glycerine polymethacrylates.
The preparation method of wrinkle antiallergic composition is gone in a kind of moisturizing, is included the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
Moisturizing goes the moisturizing of preparation method and the embodiment 1 of wrinkle antiallergic composition to go to the preparation side of wrinkle antiallergic composition
Method is identical.
Embodiment 3
Wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.2%,
Skin conditioning agent 12%,
Matrix components 18%,
Preservative (hydroxy acetophenone) 0.1%,
Surplus is Wudalianchi Volcanic cold spring water.
By moisturizing go wrinkle antiallergic composition total weight, the biologically active polypeptide by following weight percent group
It is grouped as：0.01% palmityl tetrapeptide -7,0.06% palmityl tripeptides -1,0.05% palmityl tripeptides -3 and 0.08% 6 victory
Peptide.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following components in percentage by weight
Composition：0.8% Rosa Damascana, 7.2% hyaluronic acid, 2% Radix Gentianae extract and 2% chlorella extract.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following components in percentage by weight group
At：10% butanediol and 8% glycerine polymethacrylates.
The preparation method of wrinkle antiallergic composition is gone in a kind of moisturizing, is included the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
Moisturizing goes the moisturizing of preparation method and the embodiment 1 of wrinkle antiallergic composition to go to the preparation side of wrinkle antiallergic composition
Method is identical.
Embodiment 4
Wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.3%,
Skin conditioning agent 13%,
Matrix components 25%,
Preservative (hydroxy acetophenone) 0.3%,
Surplus is Wudalianchi Volcanic cold spring water.
By moisturizing go wrinkle antiallergic composition total weight, the biologically active polypeptide by following weight percent group
It is grouped as：0.1% palmityl tetrapeptide -7,0.06% palmityl tripeptides -1,0.06% palmityl tripeptides -3 and 0.08% Argireline.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following components in percentage by weight
Composition：1% Rosa Damascana, 8% hyaluronic acid, 2% Radix Gentianae extract and 2% chlorella extract.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following components in percentage by weight group
At：12% butanediol and 13% glycerine polymethacrylates.
The preparation method of wrinkle antiallergic composition is gone in a kind of moisturizing, is included the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
Moisturizing goes the moisturizing of preparation method and the embodiment 1 of wrinkle antiallergic composition to go to the preparation side of wrinkle antiallergic composition
Method is identical.
Embodiment 5
Wrinkle antiallergic composition, including following components in percentage by weight are removed in a kind of moisturizing：
Biologically active polypeptide 0.5%,
Skin conditioning agent 15%,
Matrix components 30%,
Preservative (hydroxy acetophenone) 1%,
Surplus is Wudalianchi Volcanic cold spring water.
By moisturizing go wrinkle antiallergic composition total weight, the biologically active polypeptide by following weight percent group
It is grouped as：0.2% palmityl tetrapeptide -7,0.1% palmityl tripeptides -1,0.1% palmityl tripeptides -3 and 0.1% Argireline.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the skin conditioning agent is by following components in percentage by weight
Composition：1% Rosa Damascana, 8% hyaluronic acid, 3% Radix Gentianae extract and 3% chlorella extract.
The total weight of wrinkle antiallergic composition is gone by moisturizing, the matrix components are by following components in percentage by weight group
At：15% butanediol and 15% glycerine polymethacrylates.
The preparation method of wrinkle antiallergic composition is gone in a kind of moisturizing, is included the following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50
DEG C, biologically active polypeptide, skin conditioning agent and preservative is added, stirring obtains moisturizing and removes wrinkle antiallergic composition.
Moisturizing goes the moisturizing of preparation method and the embodiment 1 of wrinkle antiallergic composition to go to the preparation side of wrinkle antiallergic composition
Method is identical.
Embodiment 6
Wrinkle antiallergic composition, wherein percentage are removed in a kind of toner, including moisturizing prepared by embodiment 3,
The moisturizing goes wrinkle antiallergic composition to account for the 33% of toner total weight, and surplus is deionized water, isoprene, essence.
Test the using effect for the toner that wrinkle antiallergic composition is removed containing the moisturizing.
Tested crowd：80 23-50 Sui female volunteers divide 10 groups, and every group of 8 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, the toner prepared respectively using the present invention using 1 month, is used 2 times a day
Skin surface analysis instrument observes skin roughness, wrinkle depth, skin shine, and observes and records the effect used.Wherein, make
With rear, in use, there is not the case where skin allergy, and sensitive skin has prodigious change in the women of sensitive skin
It is kind.
1 skin roughness test result of table
| Roughness reduced rate | 80% or more | 70-80% | 60-70% | 50-60% | 40-50% | 30-40% | 30 or less |
| Number | 30 | 19 | 13 | 8 | 6 | 2 | 2 |
| Ratio | 37.5% | 23.75% | 16.25% | 10% | 7.5% | 2.5% | 2.5% |
2 wrinkle test result of table
| Wrinkle decrease rate | 40% or more | 30-40% | 20-30% | 10-20% | 10% or less |
| Number | 11 | 35 | 19 | 12 | 3 |
| Ratio | 13.75% | 43.75% | 23.75% | 15% | 3.75% |
3 skin shine test result of table
Embodiment 7
Wrinkle antiallergic composition, wherein percentage, institute are gone in a kind of lotion, including moisturizing prepared by embodiment 3
Stating moisturizing goes wrinkle antiallergic composition to account for the 48% of lotion total weight, and surplus is deionized water, isopropyl myristate, neural acyl
Amine 3, xanthans and carbomer etc..
Test the using effect for the lotion that wrinkle antiallergic composition is removed containing the moisturizing.
Tested crowd：80 23-50 Sui female volunteers divide 10 groups, and every group of 8 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face and smears toner, the lotion prepared respectively using the present invention is made 2 times a day
With 1 month, skin roughness, wrinkle depth, skin shine are observed with skin surface analysis instrument, and observe and record the effect used
Fruit.Wherein, after use, in use, there is not the case where skin allergy, and sensitive skin has in the women of sensitive skin
Prodigious improvement.
4 skin roughness test result of table
| Roughness reduced rate | 80% or more | 70-80% | 60-70% | 50-60% | 40-50% | 30-40% | 30 or less |
| Number | 12 | 31 | 19 | 12 | 3 | 2 | 1 |
| Ratio | 15% | 38.75% | 23.75% | 15% | 3.75% | 2.5% | 1.25% |
5 wrinkle test result of table
6 skin shine test result of table
Embodiment 8
Wrinkle antiallergic composition, wherein percentage are removed in a kind of Essence, including moisturizing prepared by embodiment 3,
The moisturizing goes wrinkle antiallergic composition to account for the 45% of Essence total weight, and surplus is deionized water, glycerine, pungent glycol, nerve
Amide 1, cholesterine etc..
Test the using effect for the Essence that wrinkle antiallergic composition is removed containing the moisturizing.
Tested crowd：80 23-50 Sui female volunteers divide 10 groups, and every group of 8 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face and smears toner, the Essence prepared respectively using the present invention, 2 times a day,
Using 1 month, with skin surface analysis instrument observation skin roughness, wrinkle depth, skin shine, and observes and records and use
Effect.Wherein, after use, in use, there is not the case where skin allergy, and sensitive skin in the women of sensitive skin
There is prodigious improvement.
7 skin roughness test result of table
| Roughness reduced rate | 80% or more | 70-80% | 60-70% | 50-60% | 40-50% | 30-40% | 30 or less |
| Number | 11 | 27 | 21 | 13 | 6 | 2 | 0 |
| Ratio | 13.75% | 33.75% | 26.25% | 16.25% | 7.5% | 2.5% | 0% |
8 wrinkle test result of table
| Wrinkle decrease rate | 40% or more | 30-40% | 20-30% | 10-20% | 10% or less |
| Number | 7 | 30 | 29 | 13 | 1 |
| Ratio | 8.75% | 37.5% | 36.25% | 16.25% | 1.25% |
9 skin shine test result of table
Embodiment 9
Wrinkle antiallergic composition, wherein percentage, institute are gone in a kind of face cream, including moisturizing prepared by embodiment 3
Stating moisturizing goes wrinkle antiallergic composition to account for the 58% of face cream total weight, surplus be deionized water, L-AA, 2- glucosides,
Eight white sides and avenabeta glucosan etc..
Test the using effect for the face cream that wrinkle antiallergic composition is removed containing the moisturizing.
Tested crowd：80 23-50 Sui female volunteers divide 10 groups, and every group of 8 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face and smears toner, the face cream prepared respectively using the present invention is made 2 times a day
With 1 month, skin roughness, wrinkle depth, skin shine are observed with skin surface analysis instrument, and observe and record the effect used
Fruit.Wherein, after use, in use, there is not the case where skin allergy, and sensitive skin has in the women of sensitive skin
Prodigious improvement.
10 skin roughness test result of table
| Roughness reduced rate | 80% or more | 70-80% | 60-70% | 50-60% | 40-50% | 30-40% | 30 or less |
| Number | 5 | 38 | 18 | 12 | 4 | 2 | 1 |
| Ratio | 6.25% | 47.5% | 22.5% | 15% | 5% | 2.5% | 1.25% |
11 wrinkle test result of table
| Wrinkle decrease rate | 40% or more | 30-40% | 20-30% | 10-20% | 10% or less |
| Number | 6 | 32 | 28 | 12 | 2 |
| Ratio | 7.5% | 40% | 35% | 15% | 2.5% |
12 skin shine test result of table
Embodiment 10
Wrinkle antiallergic composition, wherein percentage, institute are gone in a kind of eye cream, including moisturizing prepared by embodiment 3
Stating moisturizing goes wrinkle antiallergic composition to account for the 66% of eye cream total weight, and surplus is deionized water, purple ball algae extract, poly- second two
Alcohol -90M, glycosyl trehalose and gorgonian extract etc..
Test the using effect for the eye cream that wrinkle antiallergic composition is removed containing the moisturizing.
Tested crowd：80 23-50 Sui female volunteers divide 10 groups, and every group of 8 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, eye, the eye cream smearing eye prepared respectively using the present invention is made 2 times a day
With 1 month, eye skin roughness, wrinkle depth, skin shine are observed with skin surface analysis instrument, and observe and record use
Effect.Wherein, after use, in use, there is not the case where eye part skin allergy in the women of sensitive skin.Table 13
Skin roughness test result
| Roughness reduced rate | 80% or more | 70-80% | 60-70% | 50-60% | 40-50% | 30-40% | 30 or less |
| Number | 15 | 34 | 17 | 10 | 2 | 1 | 1 |
| Ratio | 18.75% | 42.5% | 21.25% | 12.5% | 2.5% | 1.25% | 1.25% |
14 wrinkle test result of table
| Wrinkle decrease rate | 40% or more | 30-40% | 20-30% | 10-20% | 10% or less |
| Number | 3 | 43 | 21 | 11 | 2 |
| Ratio | 3.75% | 53.75% | 26.25% | 13.75% | 2.5% |
15 skin shine test result of table
By above-mentioned analysis it is found that moisturizing prepared by the present invention go wrinkle antiallergy have excellent moisturizing, crease-resistant, antiallergic,
The effect of anti-inflammatory can go the moisturizing wrinkle antiallergy to make an addition to toner, lotion, Essence, face cream, eye cream and isolation breast etc.
Skin care kind.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, others are any should all without departing from the change made under spirit and principles of the present invention, modification, replacement, combination and simplification
For equivalent substitute mode, it is included in protection scope of the present invention.
Claims (10)
1. wrinkle antiallergic composition is removed in a kind of moisturizing, which is characterized in that including following components in percentage by weight：
Biologically active polypeptide 0.002-0.5%,
Skin conditioning agent 5-15%,
Matrix components 10-30%,
Surplus is cold spring water.
2. wrinkle antiallergic composition is removed in moisturizing according to claim 1, which is characterized in that by weight percentage, described
It further includes the preservative of 0.1-1% that wrinkle antiallergic composition is removed in moisturizing, and the preservative is parahydroxyacet-ophenone.
3. wrinkle antiallergic composition is removed in moisturizing according to claim 1 or 2, which is characterized in that the biologically active polypeptide
Selected from one or more of palmityl tetrapeptide -7, palmityl tripeptides -1, palmityl tripeptides -3 and Argireline.
4. wrinkle antiallergic composition is removed in moisturizing according to claim 3, which is characterized in that go wrinkle antiallergy combination by moisturizing
The total weight of object, the biologically active polypeptide consist of the following components in percentage by weight：0.0008-0.2% palmityls four
Peptide -7,0.0002-0.1% palmityl tripeptides -1,0.0005-0.1% palmityl tripeptides -3 and 0.0005-0.1% Argirelines.
5. wrinkle antiallergic composition is removed in moisturizing according to claim 1 or 2, which is characterized in that the skin conditioning agent choosing
From the one or more of Rosa Damascana, hyaluronic acid, Radix Gentianae extract and chlorella extract.
6. wrinkle antiallergic composition is removed in moisturizing according to claim 5, which is characterized in that go wrinkle antiallergy combination by moisturizing
The total weight of object, the skin conditioning agent consist of the following components in percentage by weight：0.5-1% Rosa Damascanas, 2-8% are saturating
Bright matter acid, 1-3% Radix Gentianae extracts and 1.5-3% chlorella extracts.
7. wrinkle antiallergic composition is removed in moisturizing according to claim 1 or 2, which is characterized in that the matrix components are selected from
One or both of butanediol and glycerine polymethacrylates；The cold spring water is Wudalianchi Volcanic cold spring water, PH
Value is 6.5-7.5, and micronutrient levels is：Potassium 75-90mg/L, iron 0.1-0.5mg/L, sodium 60-75mg/L, cobalt 0.06-
0.07mg/L, magnesium 75-90mg/L, iodine 0.01-0.016mg/L, calcium 95-110mg/L, selenium 0.001-0.002mg/L, zinc 0.06-
0.08mg/L, metasilicic acid 65-75mg/L, lithium 0.02-0.05mg/L, carbon dioxide 1300-1600mg/L, strontium 1.01-1.30mg/
L。
8. wrinkle antiallergic composition is removed in moisturizing according to claim 7, which is characterized in that go wrinkle antiallergy combination by moisturizing
The total weight of object, the matrix components consist of the following components in percentage by weight：3-15% butanediols and 7-15% glycerine
Polymethacrylates.
9. the preparation method of wrinkle antiallergic composition is gone in the moisturizing described in any one of claim 1-8, which is characterized in that including
Following steps：
1) biologically active polypeptide, skin conditioning agent, matrix components, preservative and cold spring water are weighed by weight ratio；
2) cold spring water and matrix components are stirred evenly, is heated to 80-100 DEG C, kept the temperature 20-60min, be cooled to 40-50 DEG C, add
Enter biologically active polypeptide, skin conditioning agent and preservative, stir, obtains moisturizing and remove wrinkle antiallergic composition.
10. a kind of skin care item, which is characterized in that the skin care item include that the moisturizing described in any one of claim 1-8 goes to wrinkle
Antiallergic composition, wherein percentage, the moisturizing go wrinkle antiallergic composition to account for the 5- of skin care item total weight
85%.
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Application publication date: 20180803 |