CN108135947B - 提高免疫应答和皮肤和/或粘膜屏障功能的材料和方法 - Google Patents

提高免疫应答和皮肤和/或粘膜屏障功能的材料和方法 Download PDF

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CN108135947B
CN108135947B CN201680042640.6A CN201680042640A CN108135947B CN 108135947 B CN108135947 B CN 108135947B CN 201680042640 A CN201680042640 A CN 201680042640A CN 108135947 B CN108135947 B CN 108135947B
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biofilm
skin
composition
human
culture
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CN108135947A (zh
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埃瓦·A·贝尔克斯
尼古拉斯·T·蒙苏尔
弗雷德里克·T·勃姆
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Quorum Innovations Inc
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/143—Fermentum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
CN201680042640.6A 2015-07-20 2016-07-19 提高免疫应答和皮肤和/或粘膜屏障功能的材料和方法 Active CN108135947B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562194630P 2015-07-20 2015-07-20
US62/194,630 2015-07-20
PCT/US2016/042939 WO2017015275A1 (en) 2015-07-20 2016-07-19 Materials and methods for improving immune responses and the skin and/or mucosal barrier function

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CN108135947A CN108135947A (zh) 2018-06-08
CN108135947B true CN108135947B (zh) 2022-06-14

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US (6) US9706778B2 (enExample)
EP (1) EP3324986B1 (enExample)
JP (1) JP6727285B2 (enExample)
KR (1) KR102258415B1 (enExample)
CN (1) CN108135947B (enExample)
AU (1) AU2016297539B9 (enExample)
BR (1) BR112018001187B1 (enExample)
CA (1) CA2991990C (enExample)
DK (1) DK3324986T3 (enExample)
ES (1) ES2904555T3 (enExample)
HU (1) HUE057494T2 (enExample)
IL (1) IL256973B (enExample)
MX (1) MX395076B (enExample)
PL (1) PL3324986T3 (enExample)
PT (1) PT3324986T (enExample)
WO (1) WO2017015275A1 (enExample)
ZA (1) ZA201800209B (enExample)

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BRPI0811530B1 (pt) 2007-05-14 2019-01-02 Research Foundation Of State Univ Of New York composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície
WO2017015275A1 (en) * 2015-07-20 2017-01-26 Quorum Innovations, Llc Materials and methods for improving immune responses and the skin and/or mucosal barrier function
EP3579930B1 (en) 2017-02-10 2026-05-20 De Maio Domingos, Mauricio METHOD FOR PROVIDING AN INJECTION TREATMENT PLAN FOR A SUBJECT WITH A TIRED APPEARANCE
US11253454B2 (en) * 2017-03-10 2022-02-22 Johnson & Johnson Consumer Inc. Method for affecting touch
GB201807576D0 (en) 2018-05-09 2018-06-20 Skinbiotherapeutics Plc Compositions and uses thereof
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
EP3685669A1 (en) * 2019-01-23 2020-07-29 Chrisal NV Composition for the decontamination and inoculation of surfaces
EP3741398A1 (en) * 2019-05-20 2020-11-25 Medizinische Hochschule Hannover Method for coating a medical device and coated medical device
IL293368B2 (en) * 2019-11-26 2026-05-01 Quorum Innovations Llc New barrier and protective preparations and their use
US12195502B2 (en) 2020-05-06 2025-01-14 Quorum Innovations, Llc Protein, and therapeutic and cosmetic uses thereof
KR102167387B1 (ko) * 2020-05-14 2020-10-19 코스맥스 주식회사 피부 장벽 강화, 피부 보습 또는 항노화를 위한 조성물
CN116133669A (zh) 2020-06-06 2023-05-16 群体创新有限责任公司 用于抑制包括冠状病毒感染的病毒感染的材料和方法
MX2023003595A (es) * 2020-09-29 2023-04-05 Unilever Ip Holdings B V Una composicion para el cuidado personal que comprende aminoacidos.
US20220142560A1 (en) * 2020-11-06 2022-05-12 Johnson & Johnson Consumer Inc. Microbiome and metobolome clusters to evaluate skin health
KR102573754B1 (ko) * 2021-02-25 2023-09-01 주식회사 차메디텍 신규의 펩타이드 및 이를 포함하는 피부장벽 강화 또는 피부가려움증 억제를 위한 화장료 조성물
KR102389749B1 (ko) * 2021-05-14 2022-04-22 주식회사 세바바이오텍 피부장벽강화 및 항주름 활성을 갖는 피부 유래 락토바실러스 퍼멘텀 아종 세바­１０１ 균주 및 이의 용도
CN113832050B (zh) * 2021-08-13 2022-10-21 广东省科学院微生物研究所(广东省微生物分析检测中心) 一株高效合成烟酰胺、抗光老化的发酵乳杆菌xjc60及其应用
CN114717162A (zh) * 2022-05-17 2022-07-08 廖梅香 发酵乳杆菌及其应用
CN118126875B (zh) * 2024-02-05 2024-11-05 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一株表皮葡萄球菌及其应用

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US20260034184A1 (en) 2026-02-05
HUE057494T2 (hu) 2022-05-28
AU2016297539A1 (en) 2018-02-08
US10004772B2 (en) 2018-06-26
PL3324986T3 (pl) 2022-04-04
EP3324986B1 (en) 2021-11-24
US20170020139A1 (en) 2017-01-26
JP6727285B2 (ja) 2020-07-22
US11564957B2 (en) 2023-01-31
ZA201800209B (en) 2018-12-19
IL256973A (en) 2018-03-29
BR112018001187B1 (pt) 2022-02-15
US12440521B2 (en) 2025-10-14
US20230165915A1 (en) 2023-06-01
IL256973B (en) 2020-06-30
CA2991990A1 (en) 2017-01-26
JP2018527322A (ja) 2018-09-20
AU2016297539B9 (en) 2019-11-28
PT3324986T (pt) 2022-01-26
MX395076B (es) 2025-03-24
US20170296599A1 (en) 2017-10-19
AU2016297539B2 (en) 2019-10-31
KR20180023012A (ko) 2018-03-06
ES2904555T3 (es) 2022-04-05
WO2017015275A1 (en) 2017-01-26
DK3324986T3 (da) 2022-01-31
US20170224748A1 (en) 2017-08-10
US9706778B2 (en) 2017-07-18
CA2991990C (en) 2024-04-16
EP3324986A1 (en) 2018-05-30
KR102258415B1 (ko) 2021-05-28
BR112018001187A2 (pt) 2018-09-11
HK1253067A1 (zh) 2019-06-06
CN108135947A (zh) 2018-06-08
EP3324986A4 (en) 2019-01-09
US10617726B2 (en) 2020-04-14
US20200215130A1 (en) 2020-07-09
MX2018000870A (es) 2018-05-15

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