CA2991990C - Biological activities of lactobacillus fermentum qi6 biofilm for improving skin and/or mucosal barrier functions - Google Patents

Biological activities of lactobacillus fermentum qi6 biofilm for improving skin and/or mucosal barrier functions Download PDF

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Publication number
CA2991990C
CA2991990C CA2991990A CA2991990A CA2991990C CA 2991990 C CA2991990 C CA 2991990C CA 2991990 A CA2991990 A CA 2991990A CA 2991990 A CA2991990 A CA 2991990A CA 2991990 C CA2991990 C CA 2991990C
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Prior art keywords
biofilm
skin
composition
activity
human
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CA2991990A
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English (en)
French (fr)
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CA2991990A1 (en
Inventor
Eva A. Berkes
Nicholas T. MONSUL
Frederick T. BOEHM
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Quorum Innovations LLC
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Quorum Innovations LLC
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20Bacteria; Substances produced thereby or obtained therefrom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/143Fermentum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
CA2991990A 2015-07-20 2016-07-19 Biological activities of lactobacillus fermentum qi6 biofilm for improving skin and/or mucosal barrier functions Active CA2991990C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562194630P 2015-07-20 2015-07-20
US62/194,630 2015-07-20
PCT/US2016/042939 WO2017015275A1 (en) 2015-07-20 2016-07-19 Materials and methods for improving immune responses and the skin and/or mucosal barrier function

Publications (2)

Publication Number Publication Date
CA2991990A1 CA2991990A1 (en) 2017-01-26
CA2991990C true CA2991990C (en) 2024-04-16

Family

ID=57835147

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2991990A Active CA2991990C (en) 2015-07-20 2016-07-19 Biological activities of lactobacillus fermentum qi6 biofilm for improving skin and/or mucosal barrier functions

Country Status (17)

Country Link
US (5) US9706778B2 (enExample)
EP (1) EP3324986B1 (enExample)
JP (1) JP6727285B2 (enExample)
KR (1) KR102258415B1 (enExample)
CN (1) CN108135947B (enExample)
AU (1) AU2016297539B9 (enExample)
BR (1) BR112018001187B1 (enExample)
CA (1) CA2991990C (enExample)
DK (1) DK3324986T3 (enExample)
ES (1) ES2904555T3 (enExample)
HU (1) HUE057494T2 (enExample)
IL (1) IL256973B (enExample)
MX (1) MX395076B (enExample)
PL (1) PL3324986T3 (enExample)
PT (1) PT3324986T (enExample)
WO (1) WO2017015275A1 (enExample)
ZA (1) ZA201800209B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
CN108135947B (zh) * 2015-07-20 2022-06-14 群体创新有限责任公司 提高免疫应答和皮肤和/或粘膜屏障功能的材料和方法
WO2018146550A1 (en) 2017-02-10 2018-08-16 De Maio Domingos Mauricio Methods and systems for preventing, correcting, transforming, and modifying facial, aesthetics, and consulting patients regarding the same
US11400037B2 (en) * 2017-03-10 2022-08-02 Johnson & Johnson Consumer Inc. Composition having reduced residue
GB201807576D0 (en) 2018-05-09 2018-06-20 Skinbiotherapeutics Plc Compositions and uses thereof
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
EP3685669A1 (en) * 2019-01-23 2020-07-29 Chrisal NV Composition for the decontamination and inoculation of surfaces
EP3741398A1 (en) * 2019-05-20 2020-11-25 Medizinische Hochschule Hannover Method for coating a medical device and coated medical device
KR20220118438A (ko) * 2019-11-26 2022-08-25 쿼럼 이노베이션즈 엘엘씨 신규한 보호 장벽 조성물 및 그의 용도
CN115776986A (zh) * 2020-05-06 2023-03-10 群体创新有限责任公司 新型蛋白质及其治疗和美容用途
KR102167387B1 (ko) 2020-05-14 2020-10-19 코스맥스 주식회사 피부 장벽 강화, 피부 보습 또는 항노화를 위한 조성물
WO2021248111A1 (en) * 2020-06-06 2021-12-09 Quorum Innovations, Llc Materials and methods for inhibiting a viral infection, including a coronavirus infection
CA3193765A1 (en) * 2020-09-29 2022-04-07 Anindya Dasgupta A personal care composition comprising amino acids
KR102573754B1 (ko) * 2021-02-25 2023-09-01 주식회사 차메디텍 신규의 펩타이드 및 이를 포함하는 피부장벽 강화 또는 피부가려움증 억제를 위한 화장료 조성물
KR102389749B1 (ko) * 2021-05-14 2022-04-22 주식회사 세바바이오텍 피부장벽강화 및 항주름 활성을 갖는 피부 유래 락토바실러스 퍼멘텀 아종 세바­101 균주 및 이의 용도
CN113832050B (zh) * 2021-08-13 2022-10-21 广东省科学院微生物研究所(广东省微生物分析检测中心) 一株高效合成烟酰胺、抗光老化的发酵乳杆菌xjc60及其应用
CN114717162A (zh) * 2022-05-17 2022-07-08 廖梅香 发酵乳杆菌及其应用
CN118126875B (zh) * 2024-02-05 2024-11-05 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一株表皮葡萄球菌及其应用

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AUPS057102A0 (en) * 2002-02-15 2002-03-07 Vri Biomedical Ltd Compositions and methods for treatment of skin disorders
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
EP1736537A1 (en) * 2005-06-22 2006-12-27 OrganoBalance GmbH Methods and means for protecting the skin against pathogenic microorganisms
JP2007284360A (ja) * 2006-04-13 2007-11-01 Mitsukan Group Honsha:Kk 乳酸菌由来のppar依存的遺伝子転写活性化組成物
BRPI0719431A2 (pt) * 2006-12-01 2013-12-03 Organobalance Gmbh Composição, kit, uso de uma combinação de microorganismo, e, método para a produção da composição ou do kit.
EP2227239A2 (en) * 2007-12-06 2010-09-15 Arla Foods Amba Probiotic bacteria and regulation of fat storage
CZ2009724A3 (cs) * 2009-11-04 2011-02-09 Bio Agens Research And Development - Bard, S.R.O. Protiplísnová smes s houbovým organismem Pythium oligandrum
CN103025328A (zh) * 2010-04-16 2013-04-03 达沃斯生命科学有限公司 用于皮肤应用的至少一种维生素e成分和酪氨酸酶抑制剂协同相互作用
JP6149279B2 (ja) * 2011-02-09 2017-06-21 オーガノバランス ゲーエムベーハー 皮膚状態の治療に使用するためのペプチド
CN103687604A (zh) 2011-03-01 2014-03-26 群体创新有限责任公司 用于治疗与致病生物膜相关之病症的材料和方法
CN102226157B (zh) * 2011-05-06 2013-01-09 北京龙科方舟生物工程技术有限公司 一株发酵乳杆菌及其应用
CN104010648A (zh) * 2011-12-07 2014-08-27 可尔必思株式会社 包含乳酸菌或其处理物的脂质代谢和/或糖代谢改善剂
CN108135947B (zh) * 2015-07-20 2022-06-14 群体创新有限责任公司 提高免疫应答和皮肤和/或粘膜屏障功能的材料和方法

Also Published As

Publication number Publication date
US9706778B2 (en) 2017-07-18
US10617726B2 (en) 2020-04-14
HUE057494T2 (hu) 2022-05-28
JP6727285B2 (ja) 2020-07-22
CN108135947A (zh) 2018-06-08
US20170224748A1 (en) 2017-08-10
DK3324986T3 (da) 2022-01-31
CA2991990A1 (en) 2017-01-26
PT3324986T (pt) 2022-01-26
WO2017015275A1 (en) 2017-01-26
US20200215130A1 (en) 2020-07-09
BR112018001187A2 (pt) 2018-09-11
BR112018001187B1 (pt) 2022-02-15
US20170020139A1 (en) 2017-01-26
IL256973B (en) 2020-06-30
EP3324986A4 (en) 2019-01-09
JP2018527322A (ja) 2018-09-20
EP3324986B1 (en) 2021-11-24
AU2016297539A1 (en) 2018-02-08
KR20180023012A (ko) 2018-03-06
MX2018000870A (es) 2018-05-15
CN108135947B (zh) 2022-06-14
US10004772B2 (en) 2018-06-26
MX395076B (es) 2025-03-24
ES2904555T3 (es) 2022-04-05
US11564957B2 (en) 2023-01-31
EP3324986A1 (en) 2018-05-30
AU2016297539B9 (en) 2019-11-28
PL3324986T3 (pl) 2022-04-04
HK1253067A1 (zh) 2019-06-06
IL256973A (en) 2018-03-29
US20170296599A1 (en) 2017-10-19
AU2016297539B2 (en) 2019-10-31
KR102258415B1 (ko) 2021-05-28
ZA201800209B (en) 2018-12-19
US12440521B2 (en) 2025-10-14
US20230165915A1 (en) 2023-06-01

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